LOCUS       DAVKEV010000001       103510 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVKEV010000001 DAVKEV010000000
VERSION     DAVKEV010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 103510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 103510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..103510
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.001"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            491..1009
                     /locus_tag="VWZ68_000001"
     CDS             491..1009
                     /locus_tag="VWZ68_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEU9371114.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            1139..1645
                     /locus_tag="VWZ68_000002"
     CDS             1139..1645
                     /locus_tag="VWZ68_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEU9371115.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            1645..1815
                     /locus_tag="VWZ68_000003"
     CDS             1645..1815
                     /locus_tag="VWZ68_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371116.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            1847..3079
                     /gene="clpX"
                     /locus_tag="VWZ68_000004"
     CDS             1847..3079
                     /gene="clpX"
                     /locus_tag="VWZ68_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEU9371117.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            3088..3675
                     /locus_tag="VWZ68_000005"
     CDS             3088..3675
                     /locus_tag="VWZ68_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEU9371118.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            3686..4066
                     /locus_tag="VWZ68_000006"
     CDS             3686..4066
                     /locus_tag="VWZ68_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEU9371119.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            4118..5008
                     /gene="rapZ"
                     /locus_tag="VWZ68_000007"
     CDS             4118..5008
                     /gene="rapZ"
                     /locus_tag="VWZ68_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEU9371120.1"
                     /translation="MTKKQFHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            5005..5982
                     /locus_tag="VWZ68_000008"
     CDS             5005..5982
                     /locus_tag="VWZ68_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEU9371121.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            5979..6890
                     /gene="whiA"
                     /locus_tag="VWZ68_000009"
     CDS             5979..6890
                     /gene="whiA"
                     /locus_tag="VWZ68_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEU9371122.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(6978..8105)
                     /locus_tag="VWZ68_000010"
     CDS             complement(6978..8105)
                     /locus_tag="VWZ68_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU9371123.1"
                     /translation="MWMEELPNGKFKYFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSESVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESD
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(8384..9334)
                     /locus_tag="VWZ68_000011"
     CDS             complement(8384..9334)
                     /locus_tag="VWZ68_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HEU9371124.1"
                     /translation="MKPFKTIEEQIATLKIRGLSITDESKAAKYLLSNNYYNIINGYS
                     KFFQHPGTDTYIDGVTFDEVSSLYTFDKDVKRAILQAILEAEHHIKSITAHRFAEAYP
                     SQKYAYLNTNSYADNKILDVGFIVSKLSKIINTNKRYRGNSIHHYAHTHSDVPIWVLT
                     DYLEFGDLRTIIENLPNSLQNEIARDLVSFISTNIPDFNDVFPPETLISFLKNINEVR
                     NKCAHNNRLLNFRCRSNSTFWETIHNKEILMGDDSRKTVYSTIISLQCFISKAAFNIL
                     WNTLRKKVIKLEKKLPSIDINVINQSLGFPNDWHRNEPKV"
     gene            complement(9483..10274)
                     /locus_tag="VWZ68_000012"
     CDS             complement(9483..10274)
                     /locus_tag="VWZ68_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9371125.1"
                     /translation="MDEKKRMQIIAENITHFRKQRGITQKELAKEVGITASTMTDYMK
                     LRSAPSFGVIQKLADYFGVKKSDIDTTFKEESTNSLPDAPDSLTQQIMDKVVQLTPPN
                     QKIVLRTSEELLESQNEEETKINEVSEVISLYQVEVVSETAAASGFNYGFGYDDTDRE
                     TIEVDERPPRHDIATKVSGDSMQPDYQDGDILYLVDKGLTTYNGDLAIIAYGDRSYFK
                     KIYTENGRLRLVSLNDKYEDIILDFPPAEDTHIKIYAVVGVYRGE"
     gene            complement(10518..11207)
                     /locus_tag="VWZ68_000013"
     CDS             complement(10518..11207)
                     /locus_tag="VWZ68_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEU9371126.1"
                     /translation="MIFRVKVNSSVSRPVTVEDICPNCKKPTNPDLVNSSYFSLGENK
                     TSLVLTCRCLGCKHFWTEEFIATRFLINDYTEKYEIEHIKVIPNLPSDIPISDDVEIV
                     SPIGKQIYVQALKAEHEQLDHIAGIGYRKALEFFVKDFSIVTNPDDEDKIIKMSLKQV
                     IEKYIKDEDLKTFALASAYIGNDEGHYYRNNPDKGFTDLKNYLHGVIHYMEMKLNFLD
                     AQELVNRSKKS"
     gene            11414..11578
                     /locus_tag="VWZ68_000014"
     CDS             11414..11578
                     /locus_tag="VWZ68_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371127.1"
                     /translation="MKENIEHLHERIKHFQSLIAYMSEHEKKYYLEKDWFDNPTLISI
                     EDAKKEVELL"
     gene            11597..11812
                     /locus_tag="VWZ68_000015"
     CDS             11597..11812
                     /locus_tag="VWZ68_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001198773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9371128.1"
                     /translation="MQWTLEAMRINKGLTQAELAEKFEVSSQTIARLEKDSSDIGYQL
                     LKKYMFFFNVKFDDIFLGKKYENFVNN"
     gene            11844..12044
                     /locus_tag="VWZ68_000016"
     CDS             11844..12044
                     /locus_tag="VWZ68_000016"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371129.1"
                     /translation="MESVLESLKQEKDHLEKIIKVVTSGGKFLRLPYQKKSRSISENL
                     KLISQNLDKLSEQVQQTTNQHS"
     gene            complement(12443..12634)
                     /locus_tag="VWZ68_000017"
     CDS             complement(12443..12634)
                     /locus_tag="VWZ68_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371130.1"
                     /translation="MKSFKDFRESLTAEDMQAISAKANEATKQIDHTDGLQLGKVSGL
                     TSVITTIELLEKYHEWLHS"
     gene            12753..12896
                     /locus_tag="VWZ68_000018"
     CDS             12753..12896
                     /locus_tag="VWZ68_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371131.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     RTV"
     gene            12893..13063
                     /locus_tag="VWZ68_000019"
     CDS             12893..13063
                     /locus_tag="VWZ68_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371132.1"
                     /translation="MKEAVKEFLKFRSRFTKIEWFEINQAVEARLNQKADQLKLDDVD
                     LEIISSRLEKVI"
     gene            complement(13056..13295)
                     /locus_tag="VWZ68_000020"
     CDS             complement(13056..13295)
                     /locus_tag="VWZ68_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371133.1"
                     /translation="MTEIHACLCGNWVNLSADDDCVMGPNMASPYIWWEENAELYSPI
                     SKPEANSMYHQDYIYIHYRGADYRIHPMFIQIVSR"
     gene            13413..13685
                     /locus_tag="VWZ68_000021"
     CDS             13413..13685
                     /locus_tag="VWZ68_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371134.1"
                     /translation="MEAVEIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETSKKMRSAG"
     gene            13682..13897
                     /locus_tag="VWZ68_000022"
     CDS             13682..13897
                     /locus_tag="VWZ68_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371135.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEKRWNIFTW"
     gene            13876..14064
                     /locus_tag="VWZ68_000023"
     CDS             13876..14064
                     /locus_tag="VWZ68_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371136.1"
                     /translation="MEYIYLVTIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMNL
                     RNSDKQFTYDVEPPEGLK"
     gene            14076..14417
                     /locus_tag="VWZ68_000024"
     CDS             14076..14417
                     /locus_tag="VWZ68_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371137.1"
                     /translation="MTQAERIREYYREHPAASYDEVAEVVGTTNSNVRANLAKDIKAG
                     RCVRLEDKSYDYSPYYNHTQALTELVDWKNDNRREWVDMLTRAAEKETDSNVMRLLIK
                     EANKLMKEVTK"
     gene            14418..14648
                     /locus_tag="VWZ68_000025"
     CDS             14418..14648
                     /locus_tag="VWZ68_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371138.1"
                     /translation="MVRNKIGDLTNTLFAQLETLDDRDLTADELKVELHRSKQMVAIS
                     GQILQAGQLALDAEKFKDKVGEVNAPIALLEG"
     gene            14662..15384
                     /locus_tag="VWZ68_000026"
     CDS             14662..15384
                     /locus_tag="VWZ68_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEU9371139.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTNYNKSQIGGVRKRLGLAVGKV
                     YQGRLLTKEQHDYLVLIQKNKISRNVANEMNQKFGLSLTEKQIKSYRRNNNLHSGLTG
                     RFEKGQTPHNKGKKYPNMPKNGGQFKKGNRPPNYVPVGTINYTTNGYPKEKIGEPNQW
                     VLKHRKVWEDHHGLIPKGYSIVFLDGDKTNYDISNLACLSKNEIARMNQNHLFTSNAD
                     LTKSGIGLTKLTNKIREVEKNG"
     gene            15377..15859
                     /locus_tag="VWZ68_000027"
     CDS             15377..15859
                     /locus_tag="VWZ68_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEU9371140.1"
                     /translation="MASLYELTGQFLTIYQLDIDDETKADTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQVAQKKLDYVKDNIMAAMNVTGQTEVKSGALII
                     KIAKNPESVKVNEDDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAELVRTEKLVIK
                     "
     gene            15859..16218
                     /locus_tag="VWZ68_000028"
     CDS             15859..16218
                     /locus_tag="VWZ68_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371141.1"
                     /translation="MELMNKTRVTDSLAVVIGPESIEVLVTEGFLFDVAIRFVKVDET
                     NLDQGNEKPVFTPEYKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQN
                     WFNTALYPGVLTEKVGV"
     gene            16218..16703
                     /locus_tag="VWZ68_000029"
     CDS             16218..16703
                     /locus_tag="VWZ68_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371142.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNDKSKDNSVAETIAYIQLCYPGAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            16666..17859
                     /locus_tag="VWZ68_000030"
     CDS             16666..17859
                     /locus_tag="VWZ68_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HEU9371143.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKGVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFQNYESYISSLPNFFRWEEIEGIENAVENNGFEIKF
                     YQKRVASGNPEKLAEFRKLNLVTVDGKTAMAKQSFGRKTFERYLNQTGVAVDFPKLKP
                     VNADTPLMLQLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKFV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            17877..18194
                     /locus_tag="VWZ68_000031"
     CDS             17877..18194
                     /locus_tag="VWZ68_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371144.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            18194..19021
                     /locus_tag="VWZ68_000032"
     CDS             18194..19021
                     /locus_tag="VWZ68_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU9371145.1"
                     /translation="MAFTLPANKPQVPKDTPRNFFIYGETMSGKSYLANEFPNPIVLN
                     TDGNAEANTVPSIQLINEKDDKGRITNSVIKQLGDILLALQTQKHSYETVVIDVIDDV
                     IEMIKIAVCDELTPVGKPRLKSLSEIPYGKGYDFFNQAITELVIDLKALPMNVIYISR
                     QVSEYDDNGNATKDKPSLKDKYVNLINGNSDLMIHTEKLGNNYNREVDRKRKTYYADQ
                     VDDKAILKILATIRGAVEPAKGKLAPKKEAAKTTKPAKTEKTKEAPKKEVDSDDELF"
     gene            19041..19547
                     /locus_tag="VWZ68_000033"
     CDS             19041..19547
                     /locus_tag="VWZ68_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371146.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKNLDWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALQRKAVGSYYNLVISVTKGKDGREFRNYDLEEEEAQPLTEAD
                     IDEDDLPF"
     gene            19720..20541
                     /locus_tag="VWZ68_000034"
     CDS             19720..20541
                     /locus_tag="VWZ68_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEU9371147.1"
                     /translation="MPSMKEYALQYQKLGFSVIPINPKNKMPLIEFADKPAMTPSEIE
                     NFWDGYPNANIALKTTNFFVIDIDKHGKSNGFESLKKWKHLNLIEPTLQAKTASGGKH
                     LFYFKREDEPITQMIGFLPGVDIKAHENNYVLVAPSATDKGQYEWDLEKSKEGGTMVT
                     PSKYLIQSIKKQYGETHGYKYDGKDGLRDLVRRSHTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPTPLPEKEMMRTIESMIKKDRR"
     gene            20544..21887
                     /locus_tag="VWZ68_000035"
     CDS             20544..21887
                     /locus_tag="VWZ68_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU9371148.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSSQAMLDGMET
                     FFSERSYNPVIEYMEKAAEKWDGRKRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFILARTTNQTEYLKDKTGER
                     RFLPVMADSKRQKKHPMEIEPETIEQIWGEAVTIYRAGADLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKSTKGFVRVKDSEKTNR"
     gene            22180..22335
                     /locus_tag="VWZ68_000036"
     CDS             22180..22335
                     /locus_tag="VWZ68_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371149.1"
                     /translation="MSYTVTLFFDNMVDETHFFKKESDAAKCKAQLESKYRGNRMYKV
                     KQEKLEE"
     gene            22332..23027
                     /locus_tag="VWZ68_000037"
     CDS             22332..23027
                     /locus_tag="VWZ68_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEU9371150.1"
                     /translation="MNKQELIKRIEDLPYTEGPIADTIEINRNWILKSIEQLAESEIG
                     HADEAPRYVKNILARLRELPLHDREFWLKAIMSEFEQDFSHAKWREGYEQGKIEGMVE
                     REKVIVPQCVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPDWFYENNIEKFCLAWLDG
                     YEVEKEKRYFVKIKGNIKENMLVYGELLKRYFFTKSFSLDDVIYSHTRKELENAKIGW
                     VFDCEGFEIEEVE"
     gene            23185..23445
                     /locus_tag="VWZ68_000038"
     CDS             23185..23445
                     /locus_tag="VWZ68_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HEU9371151.1"
                     /translation="MKRFIAIWILLSAGLNIWQSIYIKKLEEKRPIVVYKADNAGAEI
                     FGKVVEKGRHGKLYTLTIRDYGVFVVTKDVYEKVKVGDEVLL"
     gene            23445..23903
                     /locus_tag="VWZ68_000039"
     CDS             23445..23903
                     /locus_tag="VWZ68_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371152.1"
                     /translation="MDDILQALAKMLNMTVDEVSSLLTTFKGNAPQIYEMFVKEKMFY
                     DLFSLFQIMSIVIFSISAVVLAVLTLIYFTYDGGFVYSYDIRTGKTEEEIKLERIERK
                     RKDLKIPLKISCISSSASLITLVIAIVLKATLAPNYIFIVNEILPKLTKR"
     gene            23951..24019
                     /locus_tag="VWZ68_000040"
                     /pseudo
     CDS             23951..24019
                     /locus_tag="VWZ68_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022916.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            24016..24453
                     /locus_tag="VWZ68_000041"
     CDS             24016..24453
                     /locus_tag="VWZ68_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371153.1"
                     /translation="MIPKFRVWVKIGKRMVFSDDILAIDYENKEIVTQQVYFENGLPD
                     DRDIYCYDFDEIELMQSTGLKDKNGKEIFEGDIVRTTRFLGRADEIGGFYEYDKEFIG
                     IVKQLEGSWVIDTGSDAVCLWTEIEENEIIGNIYENKEFGGRK"
     gene            24450..24821
                     /locus_tag="VWZ68_000042"
     CDS             24450..24821
                     /locus_tag="VWZ68_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371154.1"
                     /translation="MRPCKYPYSGRRKKQETPSPIFSARPIFDEVPIVEEVKVEFGVE
                     ASMGRIYPETLIHLDISGYGNRVHSVHRFPGILLSVGESIQLKMLFYKRLRNFTTDRF
                     LTFRESDWKFFIRDLVNEFKH"
     gene            24894..25298
                     /locus_tag="VWZ68_000043"
     CDS             24894..25298
                     /locus_tag="VWZ68_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEU9371155.1"
                     /translation="MNKAKELLKELQDLDMDIQSRIDEINELEAGLLSSPKWSEVKVQ
                     GGQTRKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRMINRLKNPKYRAVLRMTYINK
                     GTADSVCYDLNMSRTTYYRLKNEAVLALEEVI"
     gene            25379..25461
                     /locus_tag="VWZ68_000044"
     tRNA            25379..25461
                     /locus_tag="VWZ68_000044"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25410..25412,aa:Tyr,seq:gta)
     gene            25728..26207
                     /locus_tag="VWZ68_000045"
     CDS             25728..26207
                     /locus_tag="VWZ68_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEU9371156.1"
                     /translation="MAFFDYSKGGDGKLSGLRIKQKRFADEYIISGNATEAYKKAGYR
                     VSSDRVAGVEGHKLLKNPKIKSYIDERLKQLDSEKIADQQEVLGYLTSVMRGETQEQT
                     LISIGELGQTITDIDVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDISD"
     gene            26185..27483
                     /locus_tag="VWZ68_000046"
     CDS             26185..27483
                     /locus_tag="VWZ68_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEU9371157.1"
                     /translation="MSQTYQIKQNDIVVDLPKTVGAGYGQFWRSRSLYRVVKGSRGSK
                     KSKTTALNYVIRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDIGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETRRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFNKDELLQDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAESRL
                     IEELRSEHGISRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            27495..28964
                     /locus_tag="VWZ68_000047"
     CDS             27495..28964
                     /locus_tag="VWZ68_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEU9371158.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHNTESSRLKNLKSYYM
                     GDHAILNHKRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMTELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKHQAEVFTENLHYHMVLRSTDSGTTQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNKD
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRPVR"
     gene            28873..29904
                     /locus_tag="VWZ68_000048"
                     /pseudo
     CDS             28873..29904
                     /locus_tag="VWZ68_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795723.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
     gene            30264..30491
                     /locus_tag="VWZ68_000049"
     CDS             30264..30491
                     /locus_tag="VWZ68_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HEU9371159.1"
                     /translation="MAILDDLQALYDNGWDASFNYNGQVCGIFPNSIYDVVVIIADDE
                     YRASSFDDLISLQIEGKTLPEIMNEVEVQYG"
     gene            30640..30852
                     /locus_tag="VWZ68_000050"
     CDS             30640..30852
                     /locus_tag="VWZ68_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371160.1"
                     /translation="MEEWKERFKKEYYELKERFQKLDMMIGKYEKGQLEFESKCPIDS
                     LKGQRSTMWNYLRILEQRAKIEEIKL"
     gene            31022..31606
                     /locus_tag="VWZ68_000051"
     CDS             31022..31606
                     /locus_tag="VWZ68_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEU9371161.1"
                     /translation="MSEEINATVSTESTETVDTQGNVDSVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTSAETVSQSVAVLQKSWEQAVQKGVQEKLKGGAPMKQAPV
                     DSDGITKEEFARMGYQSRNELYQKNPELYKKLKG"
     gene            31613..32458
                     /locus_tag="VWZ68_000052"
     CDS             31613..32458
                     /locus_tag="VWZ68_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HEU9371162.1"
                     /translation="MTAGQTKLATMVNPEVMADMVAAKLPKLIKFTPLAYVETKLEGQ
                     PGSTLTVPAWEYAGDATEIEEGQAITPDQLTTKKTTMTIKKAGKGYEITDESLLSGLG
                     DPLGQATYQLGLAIANKIDNDLVAVAKTATQHITETPTTLEAIDKALDIFEDEEDAQY
                     VAIINPKDATKLKTAVAKEWIKGSELGANMVVSGTFGEVDGVQIVRSKKVDEGKGFLV
                     KVSPSQTQTDDANKYGAFVILLKRDVAIETDRDILKKTTVITGDEHYGVYLYDPTRVV
                     KFGGA"
     gene            32470..32652
                     /locus_tag="VWZ68_000053"
     CDS             32470..32652
                     /locus_tag="VWZ68_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HEU9371163.1"
                     /translation="MSLLLRRHYIQEEQVNQYSDLENKTLEELKDLAKEAGVAGAYKL
                     TKAEIVEVLEELKSEI"
     gene            32642..32830
                     /locus_tag="VWZ68_000054"
     CDS             32642..32830
                     /locus_tag="VWZ68_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371164.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNIASNGVT
                     ISDVLEKILPEPEFLEED"
     gene            32832..33143
                     /locus_tag="VWZ68_000055"
     CDS             32832..33143
                     /locus_tag="VWZ68_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEU9371165.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGEHSRTEGGIAVVYGENGLSTDLLQRIRMHRLARVAGHVFEA
                     E"
     gene            33124..33462
                     /locus_tag="VWZ68_000056"
     CDS             33124..33462
                     /locus_tag="VWZ68_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371166.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            33437..33952
                     /locus_tag="VWZ68_000057"
     CDS             33437..33952
                     /locus_tag="VWZ68_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEU9371167.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQASHSGISPEV
                     SVTYKSSPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            33949..34317
                     /locus_tag="VWZ68_000058"
     CDS             33949..34317
                     /locus_tag="VWZ68_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371168.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGIVDLHSELVFQFRMEN"
     gene            34320..34733
                     /locus_tag="VWZ68_000059"
     CDS             34320..34733
                     /locus_tag="VWZ68_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEU9371169.1"
                     /translation="MLANGITLSYGETKDSYTKLVGLKEVPEFGIELEKVENTTLEDT
                     VKKYEFGIGDIGELEYKFSYNNSSATAPYRVLRKAADDKKKLYFEQAYPDGTKVIFEG
                     QVSVKLGGGGVNAVIDFTLKIALQSNLTFTDGIGG"
     gene            34738..35118
                     /locus_tag="VWZ68_000060"
     CDS             34738..35118
                     /locus_tag="VWZ68_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371170.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSLEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKDKKTSKKKMTVDK"
     gene            35157..35507
                     /locus_tag="VWZ68_000061"
     CDS             35157..35507
                     /locus_tag="VWZ68_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371171.1"
                     /translation="MFLDIEGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYR
                     LSQMISNHVSLLLSKDAKAFEFWEYAPELFVEEQQAVEQERQKQALLLHKERMREFAE
                     RHNRKRKEEVNGNS"
     gene            35494..39147
                     /locus_tag="VWZ68_000062"
     CDS             35494..39147
                     /locus_tag="VWZ68_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371172.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSSSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIESTEAFKKFANGQSWQQLDYQTQQQ
                     IRLMAILEQATAKYGDTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIERIKT
                     ALDQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSITTIGLGIGVFLAESIANG
                     LGRQKERITRALVALFDNIGNISEAVGNIAQDFSSTFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVAPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLADAIKLVADGFTVFSDWCKENKEPILALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFGETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTS
                     PITWIIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICRAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIVNIFSGIGEWFSGVFQGAWDAIVNIFTPIGSWFGQ
                     RWADVTSALANIGAWFTDIFQKAWTGLTNIFSKLGLWFGERWADVTSVLANVSSWFGN
                     MFTSAYNAVKNAFSSIGGFFSGVWSTVQSIFVNAGQKVGSAVGGAFKSAVNAVLGTIE
                     NVVNDFIGMINGVLGVVRNLPGLGWVGSVSTVSLPRLARGGIVDSPTIAMIGEAGKEA
                     VVPLENTGFIQTLGRVVSSAVVNAMAGISPQGGFSSDGDIVIQIAGHEFGRVAIQEIN
                     KEHERAGQTLLKI"
     gene            39156..39506
                     /locus_tag="VWZ68_000063"
     CDS             39156..39506
                     /locus_tag="VWZ68_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371173.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSKFFEVSYPDPMDGQVTKTFYVGDRTAPSYTFTEK
                     LKPWSGAKFNLVER"
     gene            39511..45126
                     /locus_tag="VWZ68_000064"
     CDS             39511..45126
                     /locus_tag="VWZ68_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEU9371174.1"
                     /translation="MDALTRRQFDRAMFAKERTLAIRVGEYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQIAGITCKTDKKSLTVGMTTGRSLELDNVFITQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFIFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGFEAKIQAQIEAADKDFDQKVDKIKKDFNDQVELAKARAEEVKRE
                     LSDTINQRFNSFDNGPLKEAKRKAEEALRNAGASSSLAQESKRIGLDSVARLEAFKSQ
                     TTSAQTALSGDLDVLKRTIANDIRPKQAQAEAEIAKQVEALSRTKNELDGASTLLAQE
                     AKRIELDSVARLEAFKSQTTSAQTALSGDLDVLKRTIANDIRPKQAQAEAEIAKQVEA
                     LSRTKNELAGVKSAQATYEETTTRRLSELTNLANGKASKSELTQTAEELASRIASVQA
                     SGRNLFLNSLFKQDISKTGIWTTSTYTATIDSESKYLGYNALKIIGLNPSGRDGGNPK
                     VTYPVLGQFGKVIPGSTTNQDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIK
                     RYVVHIPKGWTNESKQTTNEWLFNFNQEGTVWIWMPKFEISDVDTSYSEAPEDIEGQI
                     STVESTFKQRVNSLEAGVNRLTEGLRTKADISALNVTAENIRQSVKSLETDTQNKLNQ
                     KLSQAEFEVRAGSIRQEILNATKDKADKTLVVSEAGKLREEFSKMKVGGRNLWIKSKT
                     VGAVIEKLPENHVTGQKECYRLENNSTLTFNLEPDFSSRLYQKVTFSAWIKYENVVQG
                     RNFWNVFNCFKHYLFRKNSETGVQSGPDYATLGMYKGSADWKYITFTYDYSEKTNFDQ
                     LKTSLRFNLEGATSGTAWVTGIKVEIGSVATDWSPAPEDGENELLVAKTEFKRTADGL
                     STKMAAVESYVGQDGQRQEALQRYTREESTRQATAVRELVNRDFVGKATYQEDVKGIN
                     QRIEAVKTSANKDIASQIASYRQSVDGKFTDISSQITTYKQDVGGQISGLSNRLTSSE
                     QGTTTQISNISNRINSNKQGTDNQISNLKTQVATNKDNAERQMGRISDQVSANKANAD
                     SQFANVTNQLARKVETTDFQRVKETSKLYERILGNTENGIADKVARMALTNQLFQVEV
                     GKYSVSGPNLIKNSDFKNATNEWGSTQNLGRLVKHSFYHNGQKDLMRLSNATKNENFL
                     YSHRFNLERNTDYVLNFRGFNNSALASYDVYILGRRAGESDGFTIVKKVVSSKKLSTS
                     RCEDVSVTFNSGEMDNAYIRFDNNGSSSGTADLYITEVDLYKGYKPRTWQPHPEDAVA
                     DANKKLEATQTKMTQLAGSWVVENINSAGDIISGINLGANGHNRFVGKLTHITGETLI
                     DRAVIKSAMVDKLKTGNFEAGSVTTTILDAEAVTAEKLKVDDALIRKLTANDAFIDRL
                     TSKRIFSTKVESVISSSTFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGAG
                     HGVRTAFWANWGNNWNYAGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRANFYGNTT
                     FSRSPVFSNGIELGSKDVLGDGWNPKGGRNAVVWWNQVGSGSVKYWMEQKSDRRLKEN
                     ITDTAVKALDKINRLRMVAFDFIENKKHEEIGLIAQEAETIVPRIVSRDPENPDGYLH
                     IDYTALVPYLIKAIQELNQKIEKMEKTIA"
     gene            45221..45424
                     /locus_tag="VWZ68_000065"
     CDS             45221..45424
                     /locus_tag="VWZ68_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371175.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMITNNILSIQLDEQREGNQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            45427..45777
                     /locus_tag="VWZ68_000066"
     CDS             45427..45777
                     /locus_tag="VWZ68_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371176.1"
                     /translation="MAETNQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQLKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTDPTVKPKE"
     gene            45787..46086
                     /locus_tag="VWZ68_000067"
     CDS             45787..46086
                     /locus_tag="VWZ68_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371177.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHAVGDIQKEMVRMNDRMEEIEKGE"
     gene            46090..46422
                     /locus_tag="VWZ68_000068"
     CDS             46090..46422
                     /locus_tag="VWZ68_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEU9371178.1"
                     /translation="MQQITEIITNGAISILVILAGIAVKAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            46426..47382
                     /locus_tag="VWZ68_000069"
     CDS             46426..47382
                     /locus_tag="VWZ68_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU9371179.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKQDIENGLRAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKNTWYYLDAKEG
                     AMVSNAFVQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            complement(47634..48602)
                     /locus_tag="VWZ68_000070"
     CDS             complement(47634..48602)
                     /locus_tag="VWZ68_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU9371180.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELESVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFVPSQLLGDGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            48738..49595
                     /locus_tag="VWZ68_000071"
     CDS             48738..49595
                     /locus_tag="VWZ68_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEU9371181.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            49582..50361
                     /locus_tag="VWZ68_000072"
     CDS             49582..50361
                     /locus_tag="VWZ68_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEU9371182.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            50385..51737
                     /locus_tag="VWZ68_000073"
     CDS             50385..51737
                     /locus_tag="VWZ68_000073"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEU9371183.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            51811..52185
                     /locus_tag="VWZ68_000074"
     CDS             51811..52185
                     /locus_tag="VWZ68_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEU9371184.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            52187..53035
                     /locus_tag="VWZ68_000075"
     CDS             52187..53035
                     /locus_tag="VWZ68_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU9371185.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASEFPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            53312..54079
                     /locus_tag="VWZ68_000076"
     CDS             53312..54079
                     /locus_tag="VWZ68_000076"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEU9371186.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            54091..55275
                     /locus_tag="VWZ68_000077"
     CDS             54091..55275
                     /locus_tag="VWZ68_000077"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEU9371187.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDIASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDLDLLLQAENLRQAQGKEVNPQVIKETYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            55272..57143
                     /locus_tag="VWZ68_000078"
     CDS             55272..57143
                     /locus_tag="VWZ68_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9371188.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLTTLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(57286..58470)
                     /gene="mntE"
                     /locus_tag="VWZ68_000079"
     CDS             complement(57286..58470)
                     /gene="mntE"
                     /locus_tag="VWZ68_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEU9371189.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            58774..61470
                     /locus_tag="VWZ68_000080"
     CDS             58774..61470
                     /locus_tag="VWZ68_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU9371190.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            61483..62274
                     /gene="yghU"
                     /locus_tag="VWZ68_000081"
     CDS             61483..62274
                     /gene="yghU"
                     /locus_tag="VWZ68_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEU9371191.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTESVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            62390..62800
                     /locus_tag="VWZ68_000082"
     CDS             62390..62800
                     /locus_tag="VWZ68_000082"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU9371192.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            62812..64407
                     /locus_tag="VWZ68_000083"
     CDS             62812..64407
                     /locus_tag="VWZ68_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371193.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            64474..64638
                     /locus_tag="VWZ68_000084"
     CDS             64474..64638
                     /locus_tag="VWZ68_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEU9371194.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            64717..65445
                     /gene="yaaA"
                     /locus_tag="VWZ68_000085"
     CDS             64717..65445
                     /gene="yaaA"
                     /locus_tag="VWZ68_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEU9371195.1"
                     /translation="MKILIPTAKEMNTDLPSIEAISLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTTQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(65722..66270)
                     /locus_tag="VWZ68_000086"
     CDS             complement(65722..66270)
                     /locus_tag="VWZ68_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU9371196.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            66591..67079
                     /locus_tag="VWZ68_000087"
     CDS             66591..67079
                     /locus_tag="VWZ68_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEU9371197.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGISQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            67076..68263
                     /locus_tag="VWZ68_000088"
     CDS             67076..68263
                     /locus_tag="VWZ68_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9371198.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            68256..68621
                     /locus_tag="VWZ68_000089"
     CDS             68256..68621
                     /locus_tag="VWZ68_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9371199.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            68637..69983
                     /gene="asnS"
                     /locus_tag="VWZ68_000090"
     CDS             68637..69983
                     /gene="asnS"
                     /locus_tag="VWZ68_000090"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEU9371200.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVKNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            70136..70426
                     /locus_tag="VWZ68_000091"
     CDS             70136..70426
                     /locus_tag="VWZ68_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEU9371201.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            70438..70908
                     /gene="ssbA"
                     /locus_tag="VWZ68_000092"
     CDS             70438..70908
                     /gene="ssbA"
                     /locus_tag="VWZ68_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEU9371202.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            70940..71179
                     /locus_tag="VWZ68_000093"
     CDS             70940..71179
                     /locus_tag="VWZ68_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEU9371203.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            71474..72874
                     /locus_tag="VWZ68_000094"
     CDS             71474..72874
                     /locus_tag="VWZ68_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEU9371204.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSIRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            72876..73235
                     /locus_tag="VWZ68_000095"
     CDS             72876..73235
                     /locus_tag="VWZ68_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEU9371205.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEKKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            73289..74038
                     /locus_tag="VWZ68_000096"
     CDS             73289..74038
                     /locus_tag="VWZ68_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEU9371206.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            74028..74327
                     /locus_tag="VWZ68_000097"
     CDS             74028..74327
                     /locus_tag="VWZ68_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEU9371207.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            74398..75333
                     /locus_tag="VWZ68_000098"
     CDS             74398..75333
                     /locus_tag="VWZ68_000098"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEU9371208.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRIITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENHHAFLAGAVSRKKQVVPQLTESFNA"
     gene            75419..75931
                     /locus_tag="VWZ68_000099"
     CDS             75419..75931
                     /locus_tag="VWZ68_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEU9371209.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERDLHDSDF"
     gene            75956..76564
                     /locus_tag="VWZ68_000100"
     CDS             75956..76564
                     /locus_tag="VWZ68_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEU9371210.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDRKYELAIDFDKERLTFYLA"
     gene            76665..76859
                     /locus_tag="VWZ68_000101"
     CDS             76665..76859
                     /locus_tag="VWZ68_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU9371211.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(76905..78350)
                     /locus_tag="VWZ68_000102"
     CDS             complement(76905..78350)
                     /locus_tag="VWZ68_000102"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEU9371212.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMEKSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGVDCYQIIQGKKESYPGDTAVAENYL"
     gene            78456..80078
                     /locus_tag="VWZ68_000103"
     CDS             78456..80078
                     /locus_tag="VWZ68_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU9371213.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            80281..82239
                     /locus_tag="VWZ68_000104"
     CDS             80281..82239
                     /locus_tag="VWZ68_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9371214.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            82411..83346
                     /locus_tag="VWZ68_000105"
     CDS             82411..83346
                     /locus_tag="VWZ68_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9371215.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTIYSRSKGSSVALENLLAVPKEKFE"
     gene            83371..84093
                     /locus_tag="VWZ68_000106"
     CDS             83371..84093
                     /locus_tag="VWZ68_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9371216.1"
                     /translation="MNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPSGSGKSTIV
                     RLLERFYKPLSGYILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEIL
                     IFDESTANLDADSEYAIISILYSALKEKTVVIIAHRLSTVKDVDCIFFLEGGKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            84251..85345
                     /locus_tag="VWZ68_000107"
     CDS             84251..85345
                     /locus_tag="VWZ68_000107"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU9371217.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDTRDLIADLRQALEG"
     gene            85353..86519
                     /locus_tag="VWZ68_000108"
     CDS             85353..86519
                     /locus_tag="VWZ68_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9371218.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVVTFAKR"
     gene            86612..89710
                     /locus_tag="VWZ68_000109"
     CDS             86612..89710
                     /locus_tag="VWZ68_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9371219.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVVVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            89758..90375
                     /locus_tag="VWZ68_000110"
     CDS             89758..90375
                     /locus_tag="VWZ68_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU9371220.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVQPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            90386..91720
                     /locus_tag="VWZ68_000111"
     CDS             90386..91720
                     /locus_tag="VWZ68_000111"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEU9371221.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEVEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            91730..92194
                     /locus_tag="VWZ68_000112"
     CDS             91730..92194
                     /locus_tag="VWZ68_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9371222.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            92191..92685
                     /locus_tag="VWZ68_000113"
     CDS             92191..92685
                     /locus_tag="VWZ68_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9371223.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            92766..94421
                     /gene="mltG"
                     /locus_tag="VWZ68_000114"
     CDS             92766..94421
                     /gene="mltG"
                     /locus_tag="VWZ68_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEU9371224.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGSETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            94492..94974
                     /gene="greA"
                     /locus_tag="VWZ68_000115"
     CDS             94492..94974
                     /gene="greA"
                     /locus_tag="VWZ68_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEU9371225.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            95256..95654
                     /locus_tag="VWZ68_000116"
     CDS             95256..95654
                     /locus_tag="VWZ68_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9371226.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAL
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            96075..97082
                     /locus_tag="VWZ68_000117"
                     /pseudo
     CDS             96075..97082
                     /locus_tag="VWZ68_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            97157..97357
                     /locus_tag="VWZ68_000118"
     CDS             97157..97357
                     /locus_tag="VWZ68_000118"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEU9371227.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            97392..98108
                     /gene="atpB"
                     /locus_tag="VWZ68_000119"
     CDS             97392..98108
                     /gene="atpB"
                     /locus_tag="VWZ68_000119"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEU9371228.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNILEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            98122..98616
                     /gene="atpF"
                     /locus_tag="VWZ68_000120"
     CDS             98122..98616
                     /gene="atpF"
                     /locus_tag="VWZ68_000120"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEU9371229.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            98616..99152
                     /locus_tag="VWZ68_000121"
     CDS             98616..99152
                     /locus_tag="VWZ68_000121"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEU9371230.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            99167..100672
                     /locus_tag="VWZ68_000122"
     CDS             99167..100672
                     /locus_tag="VWZ68_000122"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEU9371231.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            100688..101566
                     /locus_tag="VWZ68_000123"
     CDS             100688..101566
                     /locus_tag="VWZ68_000123"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEU9371232.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            101652..103058
                     /gene="atpD"
                     /locus_tag="VWZ68_000124"
     CDS             101652..103058
                     /gene="atpD"
                     /locus_tag="VWZ68_000124"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEU9371233.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            103069..103488
                     /locus_tag="VWZ68_000125"
     CDS             103069..103488
                     /locus_tag="VWZ68_000125"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEU9371234.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
BASE COUNT        31970 a        18878 c        23452 g        29210 t
ORIGIN      
        1 atttgaaaga gggatgtgat agtagcaccc tctttttctt tgttttatga tagttcatcc
       61 tcgagtaaat tcaagatctt gctcggaaat gaagcttata tagtagattg aatatagaca
      121 aagaccttgt gattggtaaa acattttaga aattcattta cctttcctaa tcgacttggt
      181 ttcatcttat ttcaatctat tatagtattg gggaatttct tcaaaccaca tcagcttggt
      241 cagttctacc tgcgacctca aaacttgtgc tttggtcaag ctgggtttag tttcctagtt
      301 tgctgatgga tttccattga ctataagcat ccaaccctct tttttgtctt ctaaagaatt
      361 cttaaattat cagtctattg caacttttct catataagtt ctttgtcttg ctattggttt
      421 tccttagtag tatactaagg tagtaatcat taagaagtgg ttacaaaaaa taatgaatga
      481 ggtaaagaaa atggtagaat tgaaaaaaga agcagtaaaa gacgtaacat cattgacaaa
      541 agcagcgcca gtagcattgg caaaaacaaa ggaagtcttg aaccaagctg ttgctgattt
      601 gtatgtagct cacgttgctt tgcaccaagt gcactggtat atgcatggtc gtggtttcct
      661 tgtatggcat ccaaaaatgg atgagtacat ggaagctctt gacggtcaat tggatgaaat
      721 cagcgaacgc ttgattacac tcggtggaag cccattctct acattgacag agttccttca
      781 aaatagtgaa atcgaagaag aagctggtga ataccgtaat gttgaagaaa gcttggaacg
      841 tgttcttgtt atctaccgtt acttgtcaga acttttccaa aaaggtttgg atgtcactga
      901 tgaagaaggt gacgatgtaa caaacggtat ctttgcaggc gctaaaactg aaacagataa
      961 aacaatttgg atgcttgcag ccgaacttgg acaagcacct ggtttgtaag aaataaggaa
     1021 acatagataa atctgtagga aatttcttac agattttttc tattttgtaa gctattccaa
     1081 accagtcttt ttttgagttt tttgataaaa tagtactatc agtgaaaagg atggaagcat
     1141 gactaagaaa atcgtagcta tttgggccca ggatgaagag ggtgtgattg gtaaggaaaa
     1201 tcgtctgcct tggcatttgc cagcagaatt gcagcacttt aaagaaacaa ctctgaatca
     1261 tgctatcttg atggggcgtg tgacctttga tgggatgggg cgtcgcttgc ttccaaaacg
     1321 ggaaaccctg attttgacgc gtaatccgga agaaaagata gatggggttg ctacttttca
     1381 ggacgtccag tctgttcttg actggtatca ggatcaagaa aagaatctct acattatcgg
     1441 tgggaagcaa atttttcagg cttttgaacc ttaccttgat gaagtgattg tcactcacat
     1501 tcatgctcgg gtggaaggag atacctattt ccctgaagag cttgacttgt ctctttttga
     1561 gacagtttca agcaaatttt acgccaaaga tgagaagaat ccttatgatt ttaccatcca
     1621 ataccgcaag agaaaggaag tctaatggaa cggagtttat ttggtctatt cacggctttt
     1681 ctgtgtttca tctgctttct ggcaggagca caggcttttc gtaaaaagcg ttacgggctt
     1741 tctatcctcc tttggttaaa tgcctttacc aatctggtca atagtattca tgctttttac
     1801 atgaccttat tttagataga atgacagtat agaatggaag gaaatcatgt ctacaaatag
     1861 aaaaaatgat atgatggttt attgctcatt ttgtggcaaa aaccaagaag aagtacaaaa
     1921 aataattgct ggcaacaatg cttttatttg taatgaatgc gtggagttag ctcaggaaat
     1981 cattcgagaa gaattggttg aggaagtctt ggcagacttg tctgaggtgc caaaaccaat
     2041 tgaactcctc catatcttga accactatgt aattggtcaa gatcgtgcca agcgtgcctt
     2101 ggcagtggcg gtttataacc actacaaacg catcaatttc cacgatacac gcgaagagtc
     2161 agaagatgtg gatttgcaga agtcaaacat tttgatgatt ggcccaactg gttcagggaa
     2221 aactttcctt gcccagacct tggctaagag cttgaatgtg ccttttgcta ttgcggatgc
     2281 gacagctctg acggaggctg gttatgtggg tgaggacgtg gaaaatatcc tcctcaaact
     2341 cttgcaggtt gctgacttta acatcgaacg tgcagagcgt ggcattatct atgtggatga
     2401 aattgacaag attgccaaga agagtgagaa tgtgtctatc acacgtgatg tttctggtga
     2461 aggggtgcaa caagcccttc tcaagattat cgagggaact gttgctagcg tgccgcctca
     2521 aggtggacgc aaacatccac aacaagagat gattcaagtg gatacaaaaa atatcctctt
     2581 catcgtgggt ggtgcttttg atggtattga agaaattgtc aaacaacgtc tgggtgaaaa
     2641 agtcatcgga tttggtcaaa ataataaggc gattgacgaa aacagctcat atatgcaaga
     2701 aatcatcgct gaagacattc aaaaatttgg tattatccct gagttgattg gacgcttgcc
     2761 tgtttttgcg gctcttgagc aattgaccgt tgatgacttg gttcgcatct tgaaagagcc
     2821 aagaaatgcc ttggtgaaac aataccaaac tttgctttct tatgatgatg ttgagttgga
     2881 atttgacgac gaagcccttc aagagattgc taataaagca atcgaacgga agacaggggc
     2941 gcgtggactt cgctccatta tcgaagaaac catgctagat gttatgtttg aggtgccgag
     3001 tcaggaaaat gtgaaattgg ttcgcatcac taaagaaact gtcgatggaa cggataaacc
     3061 gatcctagaa acagcctaga ggtgactatg gaacttaata cacacaatgc tgaaatcttg
     3121 ctcagtgcag ctaataagtc ccactatccg caggatgaac tgccagagat tgccctagca
     3181 gggcgttcaa atgttggtaa atccagcttt atcaacacta tgttgaaccg taagaatctc
     3241 gcccgtacat caggaaaacc tggtaaaacc cagctcctga acttttttaa cattgatgac
     3301 aagatgcgct ttgtggatgt gcctggttat ggctatgctc gtgtttctaa aaaggaacgt
     3361 gaaaagtggg ggtgcatgat tgaggagtac ttaacgactc gggaaaatct ccgtgcggtt
     3421 gtcagtctag ttgaccttcg tcatgacccg tcagcagatg atgtgcagat gtacgaattt
     3481 ctcaagtatt atgagattcc agtcatcatt gtggcgacca aggcggacaa gattcctcgt
     3541 ggtaaatgga acaagcatga atcagcaatc aaaaagaaat taaactttga cccgagtgac
     3601 gatttcatcc tcttttcatc tgtcagcaag gcagggatgg atgaggcttg ggatgcaatc
     3661 ttagaaaaat tgtgaggaaa agaaaatggc aaaaacaatt catacagata aggccccaaa
     3721 ggctatcgga ccctatgttc aaggaaaaat cgttggcaac cttttgtttg ctagcggtca
     3781 agttccccta tcccctgaaa ctggggaaat tgtaggagag aatatccaag aacagacaga
     3841 gcaagtcttg aaaaacatcg gtgctatttt ggcagaagca ggaacagact ttgaccatgt
     3901 tgtcaaaaca acttgcttct tgagcgatat gaacgacttt gttcctttta atgaggttta
     3961 ccaaacggcc ttcaaagagg aattcccagc tcgttcagct gtggaggtag ctcgtcttcc
     4021 tcgtgatgta aaagtcgaaa ttgaagtcat cgcagagatt ggataagcta gttgaagttt
     4081 ggtgttgcca aacttctttt gatataagga gaaaaagatg acaaagaaac aatttcactt
     4141 ggtgattgtg acagggatga gtggcgcagg gaaaactgta gccattcagt ccttcgagga
     4201 tctaggttat ttcaccattg ataatatgcc gccagctctc ttgcctaagt ttttgcagct
     4261 ggttgaaatt aaggaagaca atcctaagtt ggccttggta gtggatatgc gtagccgttc
     4321 tttcttttca gagattcaag ctgttttgga tgagttggaa aatcaagatg gtttggattt
     4381 caaaatcctc tttttggatg cggctgataa ggaattggtc gctcgttaca aggaaaccag
     4441 acggagtcac ccactagcag cagacggtcg tattttagat ggaatcaagt tggaacgtga
     4501 actcttggca cctttgaaaa atatgagcca aaatgtggtg gatacgactg aactcactcc
     4561 acgtgagctg cgcaaaaccc ttgcagagca gttttcagac caagaacaag cccagtcttt
     4621 ccgtatcgaa gtcatgtctt tcggatttaa gtatggaatc ccgattgatg cggacttggt
     4681 ctttgatgtc cgtttcttgc caaatcccta ttatctacca gaactgagaa accaaacggg
     4741 tgtggatgaa cctgtttatg attatgtcat gaaccatcct gagtcagaag acttttatca
     4801 acatttattg gccttgattg agccgattct gccaagttac caaaaggaag gtaagtccgt
     4861 tttgaccatt gccatgggat gtacgggtgg acaacaccgt agtgtggcat ttgctaaacg
     4921 cttggcgcag gacttatcca agaattggtc tgttaatgaa gggcatcgcg acaaagaccg
     4981 cagaaaggaa acggtaaacc gttcatgaga aaaccaaaga taacggtgat tggtggaggg
     5041 actggaattc ccgtcattct aaaaagtctg cgggaaaaag atgtggaaat cgcagctatc
     5101 gtgacggtgg cagatgatgg tggttcttca ggtgaactcc gaaaaaatat gcaacagttg
     5161 acaccgccag gtgatcttcg taatgtcctt gtggccatgt cggatatgcc taagttttat
     5221 gagaaggtct ttcagtatcg gttctctgag gatgccggag cctttgctgg ccatccattg
     5281 ggaaatctca tcattgctgg cttgtcagaa atgcagggtt caacctataa tgccatgcag
     5341 ttattgagca aatttttcca tacaacaggg aaaatttatc cttccagtga ccatcctttg
     5401 acccttcatg cagtctttca ggatgggaca gaagtggctg gagagagtca tattgtagac
     5461 catcgaggca taattgacaa tgtctatgtg accaatgccc taaacgatga tacgcctctg
     5521 gccagccgtc gagtagtgca gaccatcctt gaaagtgaca tgattgtcct agggccaggt
     5581 tccctcttta cctctatttt gcccaatatc gtgattaagg aaattgggcg ggctcttttg
     5641 gaaactaagg cagaaattgc ctatgtctgc aatatcatga cccaacgtgg ggagacggaa
     5701 cactttacag atagcgacca cgtggaagtc ttgcatcgtc accttggtcg cccttttatc
     5761 gacactgtct tggtgaatat tgaaaaagtg cctcaggaat acatgaattc caaccgtttt
     5821 gatgaatact tggtgcaagt ggaacacgat tttgtaggtc tttgtaagca agtttcgcgc
     5881 gtgatttcat ctaacttcct tcgtctggaa aatggcggtg ccttccacga tggagatttg
     5941 attgtggacg agttgatgcg cattatacag gtgaaaaaat gagtttcaca gtagcagtaa
     6001 aagaagaaat cctgggccaa caccatctga gctggcatga attatctgcc attatcaaaa
     6061 tgtctggtag catcggtctc tcgacttcgg gcttgacttt gtcagttgtg acagaaaatg
     6121 ccaaactggc ccgtcacctc tatgagtcct ttctccattt ctatgaaatc aaatctgaaa
     6181 ttcgtcacca ccaacggagc aatcttcgca agaatcgcgt ctataccgtt tttacagatg
     6241 aaaaggtgca ggatttgtta agtgatttgc acttggcaga ctctttcttt ggcctggaaa
     6301 caggtattga tgaggcgatt ttatcggatg aggaagcagg tcgtgcctat ctctgtggcg
     6361 ctttcttggc aaatgggagc attcgtgacc ctgagtcagg caagtaccag ttggaaatca
     6421 gttctgttta tctggaccac gcgcaaggaa ttgcctccct tctccaacag tttttactgg
     6481 atgccaaggt gcttgagcgc aagaaggggg ctgtgaccta tctccagcga gcagaagaca
     6541 ttatggactt cttgatagta ataggagcca tgcaggcacg tgatgatttt gagcgggtta
     6601 agattttgcg agaaacccgt aacgacctca atcgggctaa taatgccgag acagctaata
     6661 tcgctcggac agtttctgcc agcatgaaga ccattaacaa tatcagtaaa atcaaagata
     6721 tcatgggctt agaaaatttg ccagtagatt tgcaggaagt ggcgcaactg aggattcagc
     6781 acccagacta ctctatccag cagttagcag atagtctcag cacccctctg accaaaagtg
     6841 gtgtcaatca cagactcaga aaaatcaata agatagcgga tgaattataa cgatataaag
     6901 caaccccttg aattatcaat atcttcaagg ggttttgttg tgttatgaaa tcaaaaaggg
     6961 gcaatcaagg ggcagaatta aaaaatagta tctaatttat tgaccagttt atcctccata
     7021 tcctcagtag tatgagaata gatttccaaa gtcatttttg catttgagtg cccaactcga
     7081 tccattattg attttattgg gaggtcagac tctgctaaaa acgaaatatg agaatgccta
     7141 aaaatatggc tagataagtt tttttctatt ttggcctgtt ttccatattt ttttaatatc
     7201 tgtatgaagc aagctattgt tgtaggttga ttccattttt caaaacagaa aatataatca
     7261 tcgcttgaca atggctggaa acgttcgcta agtcgtacta tttgtctttg aatagcttct
     7321 atgacactct ctgatacttt gattgtccgt attgaatttg tagtctttgg tagcgtcttg
     7381 attttgttta ctgaatcaaa attacctgtg atctcaattt tgttgttttc gaagtctata
     7441 ttcttcagtt gtaaggcagt taactcacca tatctcatac cagttaatgt cagcacaaga
     7501 accatatcag cgtacttttg gtgatattct cgacgattaa ggacatcgac aagtgctttt
     7561 atttcttgca tggtgagaaa gttgttacgc tttttttcca gttcttctaa agtctttggt
     7621 ttttgaggaa tcgtagtata atcgacctcg ttgttttcaa tgtaagagta ttgaacagcg
     7681 taattaaaga tacctctgag cctatgccgt acttttttag ctgtaatata tccgttgctt
     7741 tcaataattt tttcaatagc ctcttgaaga aaacgcctgt caagattagc aagtatggta
     7801 tcggatggta tgacttcctt catcttctta tcaactgatt tacaattatg ttttgttgat
     7861 tcctttactg tttgcgccca tgatttatag aaaaggttat agatttcttc aaatgtaatg
     7921 ctttctactt gttttgtgct gagtttttta tttatcttct cttgtaacaa gatagcagct
     7981 tgatttcttg cctggggagt tttcttctcc atggttactg aaactttttt taatttctca
     8041 gtatatggat ctttatatcg ctcaaaatat ttaaatttgc catttggcaa ttcttccatc
     8101 cacattgcgt ttacctcact tttttgttaa aatgggtaca agaaaactac ctttttaatg
     8161 gttgtttcct atacatgatt tcctcacact ctccttggcc aaaatttgag tgtggggatt
     8221 ttttggttgc tatctcgtca gataataaaa taaggtgtac ctcttagaag tacaccagac
     8281 gattttatcc ttgacgaaca aggctttttt acattcttag tgtatttctt tttttaattt
     8341 ctgtcaagca gttatttcct aaatggaaat agttggtttt aatttatact tttggttcat
     8401 tacggtgcca atcattagga aaacctaaag actggttgat tacattgatg tctatagaag
     8461 gcagcttttt ctctagtttg ataacttttt ttctaagagt attccacaaa atgttgaatg
     8521 ctgctttact aataaagcat tgaaggctaa taattgttga atatacagtt tttctactgt
     8581 catctcccat caagatctct ttgttatgaa tcgtttccca aaacgtacta ttagaacggc
     8641 atctgaagtt taataagcga ttattgtgag cgcatttgtt tcgtacctcg ttaatatttt
     8701 ttagaaaaga tatcaaggtt tctggtggga aaacatcgtt aaagtcaggt atgtttgtgc
     8761 ttataaaact tactaaatcc cgtgcgattt cattttggag tgaattaggc aggttttcaa
     8821 taatcgtgcg taaatctcca aactctagat aatcagttag tacccagatt gggacatctg
     8881 aatgagtatg tgcgtagtgg tgaattgaat ttcctctgta tcgcttgttt gtgtttatga
     8941 ttttggatag ttttgataca ataaatccca cgtctaatat tttattatct gcataagaat
     9001 tggtgtttaa ataagcgtat ttttgactgg ggtaagcttc ggcgaatctg tgagcagtga
     9061 ttgacttgat atggtgttca gcttcaagaa tagcttgcaa aatggctcgt tttacatctt
     9121 tgtcaaatgt atagagactt gaaacttcgt caaatgtgac gccgtcaata taagtgtcag
     9181 taccagggtg ttgaaaaaac ttactgtatc cattgataat attgtagtaa ttgttactta
     9241 gcaggtactt agctgcttta gattcatctg taatggataa ccctctgatt tttagtgttg
     9301 cgatttgttc ctcgattgtt ttaaatggct tcaaaaaaac tcccccattc taatttagaa
     9361 tgaaggagtt tccccgtatc ggtccccgta gagatcccga cgctttttct ctaatgaatt
     9421 cattctaaat gattttttta aaaaagtcaa ctgtttttta atatttttaa aaaataattt
     9481 ttttattccc ctctatacac cccgactact gcataaatct tgatgtgtgt gtcttcggct
     9541 ggtgggaagt ctaggatgat gtcttcgtac ttgtcattga gtgacactag gcgtaagcgt
     9601 ccgttttcgg tatatatctt cttgaagtaa gaacggtctc catatgcgat aattgctaaa
     9661 tctccgttgt aggtagtcag tcctttgtct actaaataga gaatgtctcc gtcttggtag
     9721 tcgggttgca tggagtctcc actgaccttg gtcgcaatat cgtggcgtgg tggtcgctcg
     9781 tcaacctcta tagtctctct gtctgtatcg tcgtacccaa atccatagtt aaatccagaa
     9841 gctgctgccg tctcagatac aacctcaact tggtacaagc tgataacttc cgatacttcg
     9901 tttatcttcg tttcttcttc gttttggctc tccagaagct cctcagaggt ccgtagcacg
     9961 attttttgat tgggtggggt taattgcact accttatcca ttatctgctg tgtgagcgaa
    10021 tctggagcgt ctggcagtga gttggtggat tcttctttaa aagtagtatc tatatctgat
    10081 tttttaacac cgaaataatc agccagtttt tggataacac caaaagaagg agcgcttctt
    10141 aacttcatat agtctgtcat agtacttgct gtaattccaa cttctttagc caactctttt
    10201 tgggtgatgc cacgttgctt tctaaagtgt gtaatatttt cagcaataat ttgcattcgt
    10261 tttttttcgt ccatttacga ttacctcgta ttttttataa ttacattata tatcattttt
    10321 gaatgataaa caatcaaaaa tacgaaaaaa tcctattttt ttgataaaaa ctattgacaa
    10381 tacgaaaaaa tcgtattata attaaatcaa gcttaaggaa aaggaggtaa ggcaaatgaa
    10441 cgaactagaa agaacagccc tcaatgagat attgaggact gtgacatata tagctgagaa
    10501 gttggatgaa gtagattcta agatttcttt gaacgattca caagctcttg agcatcaagg
    10561 aaattgagtt tcatttccat gtagtgaata actccgtgta ggtagttctt taggtctgta
    10621 aaacctttat caggattatt tctatagtaa tgaccttcgt cgttaccgat ataagcagat
    10681 gcaagcgcaa atgttttaag gtcttcatcc ttgatatatt tttcaataac ttgttttaat
    10741 gacattttaa tgattttatc ttcatcatca ggatttgtaa caatggagaa atctttaaca
    10801 aagaactcaa gcgccttacg gtatccaata cctgcaatgt ggtctagttg ttcgtgttca
    10861 gctttcagtg cttggacata gatttgctta ccaattggag aaactatctc tacatcgtca
    10921 gatataggta tatcgctcgg aagattaggg attactttga tatgttcaat ttcgtatttt
    10981 tcggtatagt cattgattaa aaatcttgta gctataaact cctctgtcca aaagtgctta
    11041 caacctaagc atctacatgt taatactaag cttgttttat tttctccaag agaaaaataa
    11101 gaagagttca caagatctgg attggttggt tttttacaat ttgggcaaat gtcttcaacg
    11161 gttacaggcc tagaaacaga agaatttact ttcactcgaa atatcataag atttctccaa
    11221 tcgttttatt ttgattatac catatttgaa agggggtgag gaaatgagac caagacgata
    11281 tccgtatagt gggaaaaaag agtccacctt cgtaaaggca gaccctgagt taatgttgaa
    11341 tatcaataag attgatgttg gaaatataca agcgaaaaat atatttggaa aaatttaagg
    11401 agtaggagga tggatgaaag aaaatataga acatcttcat gaacgcataa agcattttca
    11461 gtcattgatt gcttatatgt ctgagcatga gaaaaagtat tatttagaaa aagattggtt
    11521 cgataaccca accctaattt ctatagaaga cgcaaaaaaa gaagtagaac tactttaaca
    11581 gaaaggaggt aggaacgtgc agtggacttt agaagctatg agaatcaaca aaggacttac
    11641 tcaagcagag ttggcagaaa aatttgaagt ttcaagtcaa acaattgcta gattagaaaa
    11701 agatagctct gatatcggtt atcagctatt gaaaaaatac atgttttttt tcaatgtgaa
    11761 attcgatgat atttttttag ggaaaaaata cgaaaatttc gtaaataact agaaacaaaa
    11821 aaataagaag gaggaacaca tagatggaaa gcgttcttga aagcttgaaa caagaaaaag
    11881 accacctcga aaaaatcatt aaggtagtta cctctggtgg taaatttctg agattgccgt
    11941 atcaaaaaaa gtcacgctcg attagtgaga atctgaaatt gatttctcaa aatcttgata
    12001 aattgagcga gcaagttcaa caaaccacga atcagcattc atgatttcaa gatgacgaaa
    12061 gaaacctgtt ttgatttcca gtttgatatc atgttacagc gactcgataa agcgattagt
    12121 gattaaattt ttgagatgta agtttttttc atgtcaaact ttttcatgtc aaatttttta
    12181 cactaataaa tattaactaa caacaagtat taaaagacaa ccagtcctac ttctctaaat
    12241 aaaagagagg gtagaaaaaa taaatacaaa ggaggtgagg aaatgagacc aagacgatat
    12301 ccgtatagtg ggaaaaaaga gtccaccttt gtaaaggcag accctgagtt agttgaaaaa
    12361 cttttaagaa acactagttt tcttgagcgt ttacaaaaaa agcctatcaa ttttcagata
    12421 gactcagaag aatttaagcg tcttagctat gaagccattc atgatacttc tcaagtaact
    12481 caatagtagt tattacagaa gtcaaaccac tgaccttccc cagttgcaat ccgtctgtat
    12541 ggtcaatctg tttagtagct tcattagctt tagcagagat agcttgcata tcttcagctg
    12601 ttaaagattc tcgaaaatct ttaaaggatt tcataaaaac tcctcctttc tattggaatt
    12661 ttgactaaaa cggtgagagg tcctagtcga gattattata gcaatttagg aggatattac
    12721 atcggtcttg aggctgattt ttggaggcaa tattggaaga taaaatcata gaacttgctg
    12781 attacttcat cagcgaatct acaacgtaca gagaagcaaa aatagcgtgt gagaagctat
    12841 tgaaacaagt cagccacgag attgaactca gggcgatgga aagtaggaca gtatgaaaga
    12901 agcagtaaag gaatttctaa aattcaggag ccgatttaca aaaatagaat ggtttgaaat
    12961 caaccaagct gtcgaagctc gtttaaatca aaaagccgac cagttgaaac tggacgacgt
    13021 agatttagaa atcatttcta gcagactaga aaaagttatc tagaaacgat ttgaatgaac
    13081 attggatgga tacgatagtc agcgccacga tagtgaatgt agatataatc ctgatggtac
    13141 atcgagtttg cttcaggttt agaaattggt gagtagagtt ctgcattttc ttcccaccaa
    13201 atgtaaggac tagccatatt tggtcccatt acacaatcgt cgtcggctga taggttcacc
    13261 caatttccgc aaagacatgc gtgaatttca gtcataatat tacctccttt ctggtttcat
    13321 tatagcagaa aaggagatag caaaaaagca cctgacggaa atcaggcgca tacttaaata
    13381 ttcaacatga ttataacacg aaaggagcaa aaatggaagc agttgaaatt gtaagaatta
    13441 aagatgtgat tattgaaaaa gtctctgcta atgatgaaga gttaaaacgt atctttggat
    13501 gttcaaaacg acaagcagga gagcgaagaa gagaaatgca aaaactccct agtcagcaaa
    13561 aacatctttt ggatagtgga caacttgtaa cgattaaagg tttctatgaa tacttgcaat
    13621 atcgtggaac taaagcttgg aaaaaagaaa tggaaacaag caagaaaatg aggtcagcag
    13681 gatgaaccta ctatcaagaa tcaaaaacta tttttcggaa gaggtcaaag aaactaatct
    13741 cgactggaaa gaggtcgctt tagacctcaa tcaatcacta attgaaacac aggaaaaact
    13801 tcaagaagcg aatcaagaaa tcgcagactt gaagaaaatc gtagcaatct ataaagaaaa
    13861 ggagaaagaa aaacgatgga atatatttac ctggtaacaa tcgtaggaat tggactatgg
    13921 tcgctagtaa ataaactaga tgaccacgct gaaatgaaac aaaaagagcg ccagctgatg
    13981 gcaaacaatg tcgcacggat gaatctgaga aattcagata agcaatttac ttatgatgta
    14041 gaaccgcctg aagggttgaa ataaggagga gaaacatgac tcaagctgaa cgaattaggg
    14101 aatattatag agagcaccct gctgcctcat atgatgaagt ggctgaggtc gttggtacaa
    14161 caaatagtaa tgtgagagcg aacctggcca aagacatcaa ggcaggcaga tgcgttcgct
    14221 tggaagataa gtcatacgat tactcgcctt actataacca tacacaggca ctcactgagt
    14281 tggttgactg gaagaatgac aacagacgtg agtgggtgga tatgctgaca agagcagcag
    14341 agaaagaaac ggatagcaac gttatgcgtt tgttaatcaa agaagcaaat aaattgatga
    14401 aagaggtgac taagtagatg gtacgaaata aaataggtga tttaactaac acgctcttcg
    14461 ctcaattaga gactctggat gatagggatc ttacagcaga tgaattaaaa gtagaattac
    14521 accgctcgaa acaaatggtc gcaatctcag gtcaaatctt acaagcaggt caattggcgc
    14581 tagatgctga aaaattcaaa gacaaggtag gtgaagtcaa tgccccgatc gctttgctgg
    14641 aaggatgagt acacggagta catgcatgaa atatgccctg gtcgtttaac tcctgaagta
    14701 accaggttgc tgaatgaaaa atttggtacg aattataaca agagtcaaat cggtggcgta
    14761 cgcaaacgtc tagggttagc agttggaaaa gtctatcaag gtcgattgct gacaaaggag
    14821 caacatgatt atcttgtatt gatccaaaaa aataagattt ctcgtaatgt cgcaaatgaa
    14881 atgaaccaaa aatttggctt atcgctaact gagaaacaga ttaagagtta tcggagaaat
    14941 aataatctac atagtggttt gacaggaaga ttcgagaaag gtcagactcc tcacaataag
    15001 gggaagaagt accccaatat gccaaaaaac ggcgggcagt tcaaaaaagg taatcgacct
    15061 ccgaattatg tacctgtcgg tactatcaac tacacaacaa acggttatcc aaaagaaaag
    15121 attggagaac ctaatcaatg ggttttgaaa caccgcaagg tttgggagga ccatcacggg
    15181 ctgataccaa aagggtactc aatcgttttt ctggacggtg ataaaacaaa ctatgatatt
    15241 tcaaatctgg catgtttatc taagaacgaa attgctagaa tgaatcaaaa tcatttattc
    15301 acgtccaacg ctgatttgac taaatcaggt attggactaa caaaacttac aaataaaatc
    15361 agagaggtag aaaaaaatgg ctagtttata cgaactaaca ggtcagttcc tgacaattta
    15421 ccaattggat atcgatgacg aaacaaaagc agacacgctt gaggccatcg attggcaaga
    15481 acaatttgaa cagaaagcag aaggatatgc ccatgttatc aagaatctag aagccgacgt
    15541 ggcaatgtac aaggctgagg aagagagctt caaagccaag aaacaggtgg cacagaaaaa
    15601 gctggattat gtcaaggata acattatggc agctatgaat gtcacggggc aaaccgaagt
    15661 taagagtggt gccctgatta taaaaattgc taagaatcca gaatcagtca aggtcaacga
    15721 agacgacctt ccgaaaaaat attttacaaa aaaagtgacg cttgcgccgg acaaaaaaac
    15781 actcaaagag ttgcttaaat ctggcaagaa agtcaaaggt gcggagcttg tccggacaga
    15841 aaagttggtg attaagtaat ggaattgatg aataaaacac gagtaacaga ttcactagca
    15901 gttgtgattg gaccagaatc gattgaagta cttgttactg aaggttttct atttgatgtt
    15961 gcgattcgtt ttgtaaaagt agacgaaaca aatcttgatc aaggaaatga aaagccagta
    16021 ttcactccgg aatacaagct ggtcacagtt gctaaataca aggaaaaacc tatctttgaa
    16081 tcggaggaag atattcgaaa atttgagaag caagcaaaag aagttaaatc gctatttgcc
    16141 tttgcaaagg taaataaaca aaattggttt aacactgccc tttatccagg agtgctgact
    16201 gagaaagttg gtgtttgatg aaaattttag ctattgatcc aagtagtaat aaaattgaaa
    16261 ccagcacaac aggagttgtc ttgttggata atgcaagatt agttgatagc tgggttgtct
    16321 cttatggtat gagaggtttc gctgattggt ttcacgaaat cggaacaaat cttgaattcg
    16381 atgtagttat tgttgaagaa tttaaggcga gggataacga caagtcgaaa gataatagcg
    16441 tggcagaaac catcgcctat atccaacttt gctatccagg tgccattctt caattcaatg
    16501 caggttacaa gtcggatatt ccaaacgatc ttttgaaaat cttagacctt tggaaatttg
    16561 aaaaaagtca tcatcaagat attcgagcag cagcaagact tggattattt tgggcaatga
    16621 gaaatgatat tgaagaagtg gttcatgata tcggaaaggt ggtgagtgag tatcacaata
    16681 acgctaagaa agtggcaagc tgaagcgatt aaaagaagtg aacatttatc taatggaatc
    16741 tttttagagg ctcttggggg cagaggcaaa actatctgtg cacttgctat tgcaaaacat
    16801 aaaaaagcta aaaaaatcat catcacaaac aatcgactag ctattctgaa tggttggata
    16861 gatgcagtca agtttatgaa ttttgataaa ggtgttgaga ttatcattca gacagataga
    16921 tatcttcaaa atcaagtcaa aaaggggcat aaattagatt gtgatgtgct gatagtagac
    16981 gaatggcaga atatgtcttc tgacaaacaa gtggccttat atcgcaaaat aaagcgaaaa
    17041 tacacgatag gtctttcagc gacaccaatt cggaaaaaag gacaaaattt ctatccgctt
    17101 gaaaaaacgg tatttggttg ggcaacccca aataataaat ttgactggca aaagactcat
    17161 ggaaaaatgg tctatgatcc atttagctat tcaaaagaga agtgggaaga ttttcaaaat
    17221 tatgaaagtt atatctcgag cttgcctaat ttcttccgct gggaagagat tgaaggaatt
    17281 gagaatgcag ttgagaataa cggttttgag attaagtttt accaaaagag agtcgcctct
    17341 ggcaatccag aaaaacttgc agaatttaga aaactaaatc ttgtaacagt ggacggcaaa
    17401 actgcaatgg ccaagcaatc gtttggaaga aagacctttg aacgctacct taatcaaaca
    17461 ggcgtagcag tcgattttcc aaaattaaag ccagtaaatg cggatacgcc attgatgtta
    17521 caacttgacg gtttaatcga acgagcacca cacgatatgt tgattgtcag taaatctaag
    17581 cagattgtca acgtcattag cgagcgccat cctgaaattg gaatctggac gggcgatatt
    17641 caagaaggac tttataagaa attcgtggtt gctactagtc aagtgttagg tgtcggagta
    17701 gacggcttgc aacacaaata ccaaactatt gtcgtattgg atccagtaga agaaggttct
    17761 ggagaatatg atgattatcg acaattgctc tggcgcataa caggaagtcg tcagcagcat
    17821 gatgtaaatg taattgaatt ttattataaa gaaagttaaa aaaagaggaa aacaaaatga
    17881 ataaaacaac tgaaatgatc gtatttcgta gccgtaaaac tggagaattt cttaattctt
    17941 acaaggacag aagttcttta gcatttgcag ctgacttttg cagcttggaa tattgtttga
    18001 agcttcctcg taaaaaatac gaagacaaca aaaagactta caaggctctt gctgcagctt
    18061 ttgactgtga aattgtcgca gttgaagcgg aatacaaatt gacctatccg aatggatcag
    18121 aagttgaacc tatcaagcgt gaccgttcat caattgagga catgattaag gatattattg
    18181 gaggggttct ctaatggcat ttacacttcc agcaaataaa ccacaagttc ctaaagatac
    18241 cccacgaaat tttttcatct acggcgaaac catgagcgga aagtcttatc ttgcaaatga
    18301 attcccaaat ccaatcgttt tgaacacaga cgggaatgca gaagctaaca ctgttccaag
    18361 cattcagctg atcaatgaaa aagatgacaa gggacgaatt accaattcag taattaagca
    18421 gcttggagat atcttgcttg ctctccagac acagaagcac tcttatgaaa cagtcgttat
    18481 tgatgtaatt gacgatgtta ttgaaatgat taagattgca gtttgtgatg aattaacccc
    18541 agttggtaaa cctcgcttga aatccttgtc ggaaattcca tacggcaaag gatacgactt
    18601 ctttaaccaa gctatcacag aattagtcat tgacctcaaa gcattgccaa tgaatgttat
    18661 ttacatcagc cgtcaggtat ctgaatatga tgacaatggc aatgccacca aagacaagcc
    18721 aagcttgaaa gataagtatg tcaatcttat caatggaaac tctgatttga tgatccacac
    18781 tgaaaaactc ggcaacaact acaaccgtga ggttgaccgc aagcgtaaga cctattatgc
    18841 ggaccaggtt gatgacaagg ccatcttgaa aatcttggca actatccgtg gggctgttga
    18901 gcctgcaaag ggcaagctag cccctaaaaa agaagcagct aagacaacta aaccagctaa
    18961 gaccgaaaaa acaaaagagg cacctaagaa agaagttgac tctgatgatg aactatttta
    19021 agaaataaag gagaatacac atgagcttac tagatatcgc aaaatcaatc aaaaaagagg
    19081 gctttgaccc acgcaaagac agcgccaacg gtcctgcacc aatcccagct ggtacttatc
    19141 cagtagtcct gaagaaagca accttcaacg tatcggacaa aggctgggaa agccttggtt
    19201 atcaatttga aatccgtggc ggtgattaca gtggacgctc tgaatttgca acatttggca
    19261 cactgactga atggaacggt aagaaccttg actgggcagt tgaacgcact atgaaattct
    19321 ttatcaaagc cttggtcctt gctggcgaca gtatgcaagg aaatgaagaa gacggtaaag
    19381 ccttggaaga ggctctacaa cgtaaggcag ttggctctta ctacaacctt gttatctctg
    19441 tgactaaggg gaaagatggc cgtgagttcc gaaactatga ccttgaagaa gaagaagcac
    19501 aaccgctgac tgaagctgat atcgatgaag atgacctccc tttctaaaaa atagcaagtt
    19561 ttgggtcatt gatgaaactg atgaaagatt aggaccattc aatacatttg aagaggctta
    19621 tcaatcgttg ttattttatt taaaaatgac tgaagatgaa tatcagtcaa actatacggc
    19681 ccaggaactt gtttatattt acaaagagga gaaaaaacca tgccgtcgat gaaagaatac
    19741 gcattacagt accaaaagtt agggttctca gtcattccaa tcaatcctaa aaacaagatg
    19801 cctttaatcg aatttgctga taaaccagcc atgactccat ctgagattga aaacttttgg
    19861 gacggctacc ctaatgcaaa cattgcccta aagactacca acttctttgt cattgatatt
    19921 gacaaacacg gcaaatcgaa cggttttgaa tcgctaaaaa aatggaaaca tctaaattta
    19981 atcgaaccga cactgcaagc taagacggct agtggcggta aacatctatt ctacttcaaa
    20041 cgagaagatg agccgatcac tcagatgatt ggattcttgc ctggtgttga tattaaggct
    20101 cacgaaaata attatgtgtt agtcgcaccc tctgccacag ataaagggca gtatgagtgg
    20161 gatctggaaa agtctaagga aggtggcacg atggtcactc cttcaaaata tttaatccag
    20221 tctataaaaa aacagtatgg cgaaactcac ggttataagt atgatggtaa ggacggtctt
    20281 agggatttag ttagacgttc acatactaga gaccgaacac agactacaga tctctttgaa
    20341 accatcgccc ttggttttgg tgatgaaggt ggacgaaatg acaaactagc aaaattcgta
    20401 ggtggtctct tatatcgtgc ggtcgacgat ggtgtagttg ttcaacttgc aagattagca
    20461 aatgcaaata gtccaacccc tttgcctgaa aaggaaatga tgcgtactat tgaaagtatg
    20521 attaaaaaag ataggaggtg attgtgattg gtaatgtagt aagtattgac tcacaaccta
    20581 agatgataac gactgccaag ggagacatca aggccaacag tccaagtaat gtgttgatgt
    20641 ctttcaaagc tgatgatcag ttgagtattt acctaaagca caacgatttt tcccaagagc
    20701 atgaactcct taaagatatc aagatcggca acactctttt taaaaaaggt gagctccctt
    20761 ctaactttga ttcagtcgta aaagtttact ttgaaagtgt gttaggtgtt gctttctcta
    20821 gccaggcgat gctggacggc atggaaactt ttttctcaga acgttcttac aatccagtca
    20881 ttgagtatat ggaaaaggct gctgaaaaat gggatggtcg taaacgaatt gaccgaatgc
    20941 ttcaggttta cctgggggct gaagatatcc ctttagtttc taaaatcgct caaatgtggc
    21001 tagttggtgc agttgctaaa gtttatgatc catacgttaa gtttgactat gttctggatc
    21061 tagtcggtgg acaaggagtt gggaaaacat ccctccttca aaaattgggt ggcgaatggt
    21121 atacggatgc cgtaacagat ttctctaata aagataatta cgacattatg ttaaagagtc
    21181 taatcgtcaa cgacgacgaa atggtggcca gtaatcggat gagctttgca gaaactaagg
    21241 cctttatttc taaaactagc ctacgttatc gtaaaccata catgaaacgc acagaagagt
    21301 ttgccaaaaa cttcatttta gctagaacta ctaaccaaac agaatacctc aaggacaaaa
    21361 ccggtgaacg tcgttttcta ccagttatgg cagatagtaa acggcaaaaa aaacatccaa
    21421 tggaaatcga gccagagaca attgaacaaa tctggggcga agccgttaca atctatcgtg
    21481 ctggtgctga tttgatgttt gatgaaaata cagaggatga actgaatatc taccgtgaac
    21541 agttcatgta tcgtgatgaa gttgaattac aagtgcttga atatcttgat atgcccgtcc
    21601 ctgaaaattg gcaaaactgg tctattcagc aacaacatca atacacaagt aaatatttcg
    21661 ataatagtag cgactttgat cctggaagca aaaaactaga taaggtctca actcgtgaaa
    21721 tgatgtacaa cttatttatg agaaattcga atgacaggaa gctgtcaacg aagattaaca
    21781 tgatcatgga taatcatcct gattggaaaa aaagtgtttt ccgggcagga ggtaaaagta
    21841 caaaagggtt cgtaagagtg aaagattcgg aaaaaactaa tcggtagcaa ttaaaaaatt
    21901 atcggtagtc atcggtagca gttgaggggg agatcggtag cattctaccg ataaaatagg
    21961 acatcggtag cacatcggta gcagtctaac cccttgatat tactgacttt tatttaatat
    22021 ttatatataa tgctactctt ctacctatat ttttaaaaaa agtatataaa ataatagtaa
    22081 taataaagaa agcctataga atagggattc ttgaaaaaaa ctttttactt tttagaattt
    22141 atcggtagca cggtagcagt ttagaaaaaa gaggtaaaaa tgtcatacac agtaacatta
    22201 ttttttgaca acatggtaga cgaaactcac ttttttaaga aagagagtga tgctgccaaa
    22261 tgcaaggctc agttagaaag caagtatcga gggaatcgaa tgtataaagt taagcaggag
    22321 aaattggaag aatgaataag caggaactga ttaaacgtat cgaggatttg ccttatacag
    22381 aggggcctat cgcagataca atcgaaatta atagaaattg gatattgaaa tcaattgaac
    22441 agctagccga atccgaaata ggtcacgcag atgaagctcc acgctacgta aagaacatac
    22501 tagcacgatt gcgagaattg ccattgcatg atagagagtt ttggttaaag gctatcatga
    22561 gcgaatttga acaggatttt agccatgcaa aatggcgaga gggctacgag caaggtaaaa
    22621 ttgagggtat ggttgaacgt gaaaaagtca tagttccgca gtgtgtggcg gaatatatag
    22681 aatttaaaaa gaaaaacaat tttcatgttt acggtgcaat gagagtaatt gaagatcatt
    22741 atgataagaa agttcctgat tggttttacg aaaataacat cgaaaaattc tgtcttgctt
    22801 ggcttgacgg ctacgaggtt gaaaaagaga agcggtattt tgttaagatt aaagggaata
    22861 ttaaagaaaa tatgttggtt tatggagaac ttttgaaaag gtatttcttt acaaaaagct
    22921 ttagtttaga cgatgttata tattcccaca cccgtaaaga actagaaaat gcaaaaatcg
    22981 gctgggtgtt tgattgtgaa gggtttgaga ttgaggaggt ggagtgatga gccttacgct
    23041 aaatagcaca attggagact tagttttggc aatcggagaa attatcgttg gttctgatgg
    23101 taaaaccact acagcgatac tggagatacc tgatcaaagc ttttacttag agattgagct
    23161 taaattgaag gaggaggtca taaattgaaa cgattcatag ctatctggat tctgctatct
    23221 gctggattga atatctggca gagtatctac attaaaaagt tagaagaaaa gcgccctatt
    23281 gtcgtctata aagctgataa cgcaggcgct gagatattcg gtaaagtcgt cgagaaagga
    23341 cggcatggca agctatacac gcttaccatt cgtgactacg gggtgttcgt ggttacgaag
    23401 gacgtgtatg agaaagtgaa agtaggggat gaggtgttac tctaatggat gatattttac
    23461 aagctttagc aaaaatgcta aatatgactg ttgatgaagt aagttctttg cttacaacat
    23521 ttaaagggaa tgcaccacag atttatgaaa tgttcgttaa agaaaagatg ttttatgatc
    23581 tcttcagtct ttttcaaatc atgtcaattg taatatttag tatttctgca gtagttttag
    23641 cagttttaac tctcatatat tttacatacg atggtggttt tgtttattcc tatgatatac
    23701 gtacaggaaa aaccgaggaa gaaattaaat tagaacgcat tgaacggaaa agaaaggact
    23761 taaaaatacc actaaaaatt agttgcattt catcaagcgc aagtttgata acattagtta
    23821 ttgcaattgt tttaaaagca actcttgcac ctaattatat attcatcgtg aatgagattt
    23881 taccaaaatt aacgaagaga taggagttat catgaacgca ctagaaaaag tcgaacaatg
    23941 gtttatcgac cgtgaaatca aagaccgaaa aggtcgctgg attgatggct cgtttgtcaa
    24001 agaggaggat ttggcatgat accgaaattt agagtgtggg taaaaatagg aaaacgtatg
    24061 gttttttcag atgacattct tgctattgac tacgaaaaca aagaaatagt gacacaacaa
    24121 gtttattttg agaatggttt accagacgat agagatatct attgttatga ttttgacgaa
    24181 atcgaactca tgcaatcaac aggactcaaa gacaagaacg gcaaggaaat ctttgaaggc
    24241 gatattgtac gaactactag atttttgggt agagctgacg aaattggcgg tttctatgag
    24301 tatgacaagg aatttatagg gattgttaag cagcttgagg gttcttgggt aattgatacg
    24361 ggcagtgacg cagtatgttt atggactgaa attgaagaaa atgaaatcat cggcaacatc
    24421 tatgaaaata aggagtttgg aggacgcaaa tgagaccttg taaatatcca tattcaggaa
    24481 gaagaaaaaa acaagaaacg ccgtcgccaa tattttctgc acgaccaatt tttgacgaag
    24541 ttccaattgt agaagaagtt aaggttgagt tcggagttga agctagtatg gggcgcatat
    24601 atccagaaac gttaatacat ttagatattt ctggatacgg aaatagagtg cattcagtac
    24661 atcgcttccc cggtatttta ctgagtgttg gtgagtcaat ccaactaaag atgcttttct
    24721 ataaaagact tagaaatttt actacagatc gtttcttgac gtttagagaa tctgattgga
    24781 agttctttat ccgggacctg gtcaacgaat ttaagcatta aaaaaagcca agacactctc
    24841 tgcctcagct aatagttctc gcaaagacta ttatatcaca aaggagacag agagtgaaca
    24901 aggctaaaga gctcttgaaa gagttgcagg atctggacat ggacatccaa agccgtatag
    24961 acgaaattaa cgagcttgag gcaggtttgc tctcaagccc taaatggtcc gaggttaaag
    25021 tccaaggtgg acagactaga aaagttgatg atgtctatac tcagttggta gtgatgaaag
    25081 aggctataga gcaggatact aaagaggtca ttaacagaaa acttgaatta ggtagaatga
    25141 tcaataggct taaaaatcca aagtacaggg cagtattaag aatgacttac atcaacaaag
    25201 gcaccgctga tagcgtttgt tatgatttga atatgagtcg tacaacctac tacaggttaa
    25261 aaaatgaggc ggtcttagct ttggaagaag ttatctaacc tcatagtgag cttatgggac
    25321 tttttggaac agcacggttc taaaaatctg ttagaatggt agtatcaaga attgaaaaga
    25381 gaggtctcag aattggtaga tggttacctg taatgtcagg gggctgtaat ggccttggag
    25441 gttcaagtcc tcccctctcc tttgagtgtt tgtgtcccag aatgagttaa atcttctggg
    25501 tggggattca catatcactc attaactcct atcactcatt aacttaaaaa tggttgcgga
    25561 agcgactgga cctcgcatga ttgcgtagct aattatattc cggataagtt ataagctaga
    25621 gggtttgatt ccctcagagg ttttaaagac tacaaaaaat aaaaaagaag tcaaaattta
    25681 atacgcacgc aaggtagtag tcgccttgca agaaggtcgc acatcgtgtg gctttttttg
    25741 attattcgaa gggtggtgat ggaaaattga gtggattgag aataaaacaa aagagatttg
    25801 cagatgagta catcatctca ggtaatgcga cggaagccta taagaaagca ggttatcgtg
    25861 tttctagtga tagagtggca ggcgttgaag gacataagtt actaaagaat cctaagatta
    25921 aaagctatat agatgaacga ctgaaacagc ttgattctga aaagattgcg gatcagcaag
    25981 aggtcttagg ttatctaact tcagtcatgc gaggagagac gcaagaacag accttgataa
    26041 gcattggaga actagggcag acgattacgg atatagatgt aggagctaaa gatagaatca
    26101 aggcggctga acttcttggt aaacggcata ggctttggac ggataaggta gaggcggatg
    26161 tttctggaac ggtggtgttt gcaaatgagt cagacatatc agattaaaca aaacgatatt
    26221 gtcgttgact tacctaagac agtaggagct ggatacggac agttctggcg ctcaagaagt
    26281 ctttatcgtg tagtcaaagg gtcccgtggt tcgaagaagt ccaagacaac cgctttgaat
    26341 tatgttatcc gtcttttgaa gtatccctgg gccaacttgc ttgttattcg tagatactcg
    26401 aataccaaca agcaatcaac ttatacggat tttaaatggg cgtgtaatgt gttgggtgtg
    26461 actcatttgt ttaaatttaa cgagtctttg cctgaaataa ccataaaagc gactggtcaa
    26521 aaaatcctat tccgtggttt ggatgatgaa ctcaaaatta catctattac agtcgatatc
    26581 ggtagtctgt gttgggcatg gttcgaggaa gcatatcaaa ttgagactga agacaagttc
    26641 agcacggttg ttgagtctat ccgtggtagc ttagatgtac ctgatttctt taaacaaatc
    26701 acagtcacat ttaacccgtg gaatgagagg cattggctca agcgtgtatt cttcgatgaa
    26761 gagacgagac gggctgacac attcgctact acaaccactt ataaatgcaa tgagtggctt
    26821 gatgaagtcg atatcaaacg ctatgaggat ttgtatcata cgaaccccag acgtgctaga
    26881 atcgtttgtg atggcgaatg gggagttgct gaaggtttaa tctacgaaaa cgtgactgtc
    26941 aaggatttca ataaagatga attactacaa gattcagcta ataaattatg tatcggtctt
    27001 gactttggtt ttactcatga tccaactgct ttgtgttgtt cgttgataaa tgacacgacg
    27061 aaagagattt atgtctttga tgaggcgtat aaagtcggat tgataaccaa agaagttgcg
    27121 aagatgataa aagacaaagg ttatcatcgc tcacaaatca ttgctgatag cgcagagtca
    27181 cggctgattg aagagctcag gtcagaacat ggcatatcta gaataaaaga gagtcggaaa
    27241 ggtaaggata gtattatggc aggcgtatcc aaattgcaag gatacgctat ttatgtgcat
    27301 ccagattgta aaaacatcat ggatgaattt tatagttact gctaccagcg agataaagaa
    27361 ggcaactggt tgaataaacc agaggataaa aacaaccact tgatggacgc tttgcgttac
    27421 agccttcaat gtatcgaagg tggaaaagca accgtccgca gacgttctga ttatggtcta
    27481 tagagaggaa agacatgtac caatatttaa cctatccacg ggatggatat gatgagggtt
    27541 ctttgaagaa agacctgatt tacaaattga taacgataca taacactgaa agctcacgct
    27601 tgaagaattt aaaaagctac tacatgggtg atcatgctat tttaaatcac aagagacgca
    27661 acgtgaacgc acccaattac aagacggtag ctaatcatgc caaggatatc gcagacacgg
    27721 ctacgggcta ttttatgggc aatcctatca agtataacaa tactgctgac ggtgatattg
    27781 atgaactact tacagccttt gatggtgctg agattgacca agtggatgcg cagaacgcac
    27841 taaatatggc tatctacggc cgtgcttacg agtacatcta tgctaaagag ggtatgactg
    27901 agttggattc aactagtatt gatccggaga atactttcat ggtctacgat gatagtattg
    27961 agcggaagcc tttgtttgcg gtctattact atgaagtaaa agacgatacg aaagacacta
    28021 ccaagcacca ggctgaggtc tttaccgaaa atctgcacta tcacatggtg ctgagaagta
    28081 cagattcagg aacaactcag agcgaggagg caacacctca caaccttggt caaatcccaa
    28141 ttatcgagta tcgcaataat cactttgcga ttggcgacta cgagcaacaa attagcttga
    28201 tagacgctta taattccttg atggggaatc gtgtcaatga taaggaacag gctgtagagt
    28261 ctatccttgt cttgtatggc acgcagttag cagacactcc agaagacgct aaggtagcaa
    28321 tgaagattct ttctgaagaa ggtcttttgg aattgccggg cgatagtgca agggctgagt
    28381 tcttgaagaa tacgctggac gaaagtgcta ctgaaatctt gcgtacagct cttaaagagg
    28441 acatctacac atttagccat gtgcctaatt tgactgatga gaatttcgca gggaatacat
    28501 caggcgtagc catggaattt aagctgatgg gccttgagat gattactaag accaaggaag
    28561 cgaactataa gcgaggattg cgtcagcgta ttgcgatttt tgctcattac ttaggcatga
    28621 agcagattgc tttagagtct cattcaatcg ttccacaatt cagtcgtggt ttgcctaaga
    28681 acttattaga aatctctcag attgtgaaca atttggaagg caaagtgacc aatagacagc
    28741 ttatttctct cttgccgttt gtggaagacc ctgacgctga gctggaagcc ttggaagaag
    28801 agaaaaagaa gaacatggaa gacatgccga tgttcaacaa agacaacacg aaacccgaag
    28861 acgaggtaga ggatgaagaa tcaggagtat tgggcgaaga ggaaagccaa tctgatttac
    28921 cagcagatgg acaaggccga aaagcaggca gaccagttcg ataaggtcta tcaggaagct
    28981 aagacttact tggataagga aatcaataag attttcgata aattccaacg tgattatggt
    29041 ctaagtcagg tagaagctag acaagtcttg aagaacatga aagacaagaa aaatctgaat
    29101 gaacttcgta aagtacttga agcgagaccg aatgacccga acatccaaag attactagct
    29161 gacttagaca gcccagctta ttctttccgc atgaagcgcc tagagcgttt gagcgacgat
    29221 ttagatcgta tgcgtgaatc tatctatcat tcggagaaga caggctcaga tgccttttat
    29281 agcgacctga tgaaggatag ttactacaag gctacctttg acctacaaca gcagacagga
    29341 ctagcatatg gcttttctgg gcttcctgag aacgagatta aacatctaca gtcttttagt
    29401 tgggtaggag atggaagtac gtactcaaca gacatctgga agaatacagg aaaacttact
    29461 tccagcataa aagatgaact cctcattagc ctcatgacag gcagagatac acgagaaact
    29521 gcacaagcaa ttgctgagag gttcaatgta ggtcagaacg atgcaaggcg tttggttcga
    29581 acagaatccg ccttttttca taaccagatg gagctactca gctatgaaga agcagacata
    29641 gaaaagtata tctttgtggc cgtcttagac aagcgtacat cacgcatttg tcaggagcat
    29701 gacaatcagg tctatgatag ggataaggct gtccctggtg tcaattgtcc gcctatgcac
    29761 ccttggtgta ggtctactac tgtcggatac gatgaggacg cagactacag caagttgaag
    29821 cgcagagcaa ggaatccaga gacaggtaaa gttgagtacg tgcctgccga tatgacttat
    29881 aaagagtggt atagcaagta tgtggatggt aatagagagt ctattaaacg taaagcgttt
    29941 gataaaacta ttaaagatgg tataatagta agtgtatcag ggactacaat tggacacact
    30001 ccgcctggca aaataggttt gcctaatagt gtagttcagc ataatgctac aaacggagat
    30061 gtccttggta gaacttacta tgatgctaga ggttttaaaa cgaaagatgt tcattttaca
    30121 aaccataaac aaccggcacg tcatccttat ggaaaaatcg gagaacatgc tcatgatttt
    30181 gtatttgatg atgaaggtaa gttcgttagt aggagtacta gggaattaac agacgatgaa
    30241 agaaaggaga atcaagatat attatggcga tattagatga tttacaagcg ttatatgata
    30301 atggatggga cgcttctttt aattataatg gtcaagtatg tggcattttc cctaattcta
    30361 tttatgatgt tgttgttatt attgcggacg acgaatatag agcatcttct tttgacgatt
    30421 tgatttcttt acagattgaa gggaaaactt taccggaaat catgaacgaa gttgaagtac
    30481 aatatggcta aagcacctag agagatctaa gtgctttttt agtacccaga aaggagacta
    30541 tccgtacgat tttcttgatt gtgaatttga agtaaaaaga atttcagtga tagcttgcga
    30601 tactatcctt atagaagcct aaaagaaagg aacagaaaaa tggaagaatg gaaagaaaga
    30661 tttaaaaaag aatactacga attgaaagaa cgattccaga agttagatat gatgattggg
    30721 aaatacgaaa aagggcaact agagtttgaa tctaaatgtc cgattgattc gttaaaaggt
    30781 cagcgttcaa ccatgtggaa ttatttaaga attctagaac aacgtgcaaa aattgaagaa
    30841 attaaactat aaaaattaac cgcatcgaaa tcgatgcggt tttcctatgc cctaaccgta
    30901 tggaatcccg tacggttttt atattgtcca aactgtaccg atgacaataa aagctgtgct
    30961 gttccgtcgc cggacgtaaa acgagattat cgagtggcga cgtaatcgct ggaggacaat
    31021 tatgtcagaa gaaatcaatg caactgtatc tactgaatca actgagactg tcgacactca
    31081 aggaaatgtt gattcagtgc aggaagaaaa gcacgaacga actttcactc gtgctgaaat
    31141 cggtaagatg ctatctgccg aacgctctaa atgggaagct gagcaagaag ccaaggaaaa
    31201 cgaagctaag aaacttgcca agatgaacgc tgacgagaaa caaaaatatc agttggatca
    31261 gcgtgagcaa gaactagctg accgtgagaa ggctattgct cgcaaggaat tgaccgcaga
    31321 agctaaagca atgctaagtg aacgtgactt acctgttgag ttagtaaatg tagttgattt
    31381 gacaagcgca gagacggtat cgcagtctgt cgctgtattg cagaaatcat gggagcaagc
    31441 cgtgcaaaaa ggcgttcaag aaaaactaaa aggcggagct ccaatgaaac aagcgccagt
    31501 cgatagtgac ggtatcacaa aagaagaatt tgctcgtatg ggttatcaga gtcgaaatga
    31561 gctctatcaa aagaacccag agctttataa gaaattgaaa ggataataga aaatgacagc
    31621 aggacaaact aaattagcca ctatggttaa tccagaagta atggcggata tggtagccgc
    31681 taaattacct aaattgatta aatttacacc gctagcgtat gtagagacaa agcttgaagg
    31741 tcaaccaggt agcactttaa cagtgccagc atgggagtat gcaggagacg ctactgaaat
    31801 tgaagaaggc caagcaatta cgccagacca attgactact aaaaagacta ctatgaccat
    31861 caaaaaagca ggtaaaggtt atgaaattac cgatgagtct cttttgtcag gtcttggtga
    31921 cccactaggt caagcgactt accagcttgg tttagctatt gccaacaaga tcgataatga
    31981 tttggtagcg gtagctaaaa ctgcaacaca acatattaca gaaactccaa caactcttga
    32041 ggcaatcgat aaagctctag atatctttga ggacgaagaa gatgcacagt atgttgctat
    32101 catcaaccct aaagatgcta ctaagctaaa aactgcagta gcaaaagaat ggattaaagg
    32161 ttcagagctt ggagcaaata tggttgtttc tggaaccttc ggtgaagttg atggtgtgca
    32221 aatcgtgcgc tctaaaaaag ttgatgaagg taaaggcttc cttgttaaag tgtcaccaag
    32281 tcaaactcag acagacgacg ctaacaaata tggagctttt gttatcttgc ttaaacgtga
    32341 tgtggctatc gaaacagacc gcgatatctt gaagaagact accgtaatca caggtgatga
    32401 acactacggc gtttaccttt acgaccctac acgagttgta aaattcggtg gcgcgtaaga
    32461 ggtgacgata tgagtttatt gctacgacgt cattatattc aagaagagca ggttaaccag
    32521 tattctgatt tagagaataa aactctagaa gagttgaagg atctagcgaa agaagcaggt
    32581 gtagcaggcg cttataagtt gacaaaagcc gaaattgtag aagttttgga ggaactaaaa
    32641 agtgaaattt aaaatcaaac aagatttcta tgattgggaa tcaaatgtga aacgactggc
    32701 aggagaggaa cttgagatta ctgaggagcg ctatgctgag ctggctgaca atattgccag
    32761 caacggtgtc actatctcag acgttcttga gaaaatcctc cctgaacctg agttcttaga
    32821 agaggattga tatgtctata gagttgctga agaaattaac aggcgaagaa gatactcagc
    32881 ttctcatgtt gctccaaacg agggctacaa atcttatctt gtcagagact aatcgcacat
    32941 ctttgacacc tgctttaagt cttttaatac ctgaggttgc tatcgaactc cacaaccgct
    33001 caggagcgga aggagagcat tctagaaccg agggtggtat agcagtagtc tacggagaaa
    33061 acggcctgtc tacggatctt ctacagcgaa tacgcatgca caggctagca agggtggcag
    33121 gtcatgtttt tgaagcagag tagactgaaa ccttatccaa tgcgacggtt tgaaaagact
    33181 gtcactgagg aaggtgtcgc gaaagaaggg tatgccaagg aagctgagac agtccgcctt
    33241 gaattgtggc cagctagtag caagctacaa tctgaattgt atggcgagcg tgtcaatgat
    33301 attttgaacg caaatgccaa caagtcagct actatcaaag taaaagatgg tgtgtgtatc
    33361 gatagtcaga cggaagtgac tcatagggtt atttctaaaa aggtctacac acatcatcaa
    33421 gttttggagt tagagcgtgt cagggctact aggggcagat aggcttatag ctaaatgtag
    33481 acgattggct agtaaaaaaa ctggcgagga tatcgtctta cgtgcggtgc acaatgctac
    33541 tataaaggtt gtccaagcag atgcaagaag actcgcacca gcgagagatg gagagcttat
    33601 aactagtatc aaaactaggg caaaaatgga cggagataag gctataggcg aagtttacac
    33661 caaccttaaa tacgctcctt atgttgagtt tggaacggga ccaataggac aagctagcca
    33721 ttctggtatt tctccagagg tcagcgtgac ttacaagtct agtccgtggt atgtacatga
    33781 agaccaaatc aatgtaggac cgtaccactt tcaaaaaatc ggggagttct acaagatgta
    33841 tggtcaacct gcccagcctt atctttatcc agctttgaga gacaatcaag agcgtgtgtc
    33901 taagaatatt tcgaattatg tccgtagaaa gataagagaa caaataaaat gattaatatc
    33961 aagcctgtta tttataaaga attgcaaaag gttgcagata atgtgaccga tacttatcct
    34021 agcgattggg agactttccc agtcgttatt tttttggaag aacaaaacaa gccgggtgat
    34081 tggtttgatg accaggaaca aaaatcctct atccgctaca aggtggatat ctttgatgat
    34141 actagcacta gtgagttagc tgttaaaatc aatcagattt ttgagtcttt aggtttgcga
    34201 agaactgact gccaagacgt gccagacccg tctcatttga gacataaggt catgcgtttt
    34261 gaaggtatcg tcgacttaca ctcagagctt gtttttcaat ttagaatgga gaattaaaca
    34321 tgttagcaaa tggaattacg ctttcttatg gcgaaacaaa agatagctat actaaacttg
    34381 ttggattgaa agaagtacca gagtttggta ttgaactcga aaaagtagaa aatactactc
    34441 ttgaagatac ggtgaagaag tacgagtttg gtattgggga cataggagaa cttgagtaca
    34501 agttctctta taataattca agcgcaactg ctccttatcg tgtattgcgt aaggcagcag
    34561 acgacaagaa gaaactctac tttgaacaag cttatccaga cggtactaag gtcatttttg
    34621 aaggccaagt atctgttaag cttggcggtg gcggtgtcaa tgccgttatc gatttcacac
    34681 ttaagattgc cttgcagtct aatcttacat ttactgatgg tattggaggt taattaaatg
    34741 gcgttaaaat acacaacttg gaaagttact gacgaaaaag agttgaagct acgtttgaca
    34801 tctcatcaag ctgcaactgt ggaagaaaaa atcggcatga acttgctgaa gattttcatg
    34861 cctgaagctg gcgaagagtt cactttaccg cctttgaaag ttatgttgtt gttagttcac
    34921 ggagccttgc agcagtatga acatgggtat tctcttgagg atgtctatga tttatacgat
    34981 gaatacgtgg acaatggcgg agaccaaaca accttcatga cagaggtgtt gatgccactc
    35041 tttgaagtat cgggttttac tccacgagga agcaaggaca agaaaacttc caagaagaaa
    35101 atgacagtag acaagtaatc ttaacggtaa ctcagattat tgagaggctt tatcctatgt
    35161 ttttggacat cgagggcaag cctcttgatt tttgggattt gacggtactt gaaatcagag
    35221 aaatgattga aagctataac cgtgtcaaaa tccaagagcg taaagaaaag attattgact
    35281 catacagact ttcgcagatg atatccaacc acgtttcttt attgttatcc aaagatgcca
    35341 aggcctttga gttctgggaa tatgcgcctg agttgtttgt agaagaacaa caagcagtag
    35401 aacaggaacg acagaaacaa gcacttttgt tgcataagga acggatgcgt gaatttgcag
    35461 agagacataa tcgaaaaagg aaggaggaag taaatggcaa ctcttgatga attgaaagtc
    35521 atgattgacg ctgagatagc gcctttcagg aagaagatga aagaagtcga gaatcaggtc
    35581 aaaggaacat ctgaccaagt gaaaaatgct actgccaaag ttcgtgaaca gtcgagctca
    35641 atcggtagtg cgtttggcaa gctggctaag ttcgctggtt ttgcaatcct tggtaagaaa
    35701 ttacttgatg ttgggatgta ttcaacgcag acggctcttg aagtatcagc gtctatgaac
    35761 caaatcaagc gacagatggg cgagagttcg caatctttct taaaatgggt taacgataat
    35821 gccaacgcta tgaatatggg tgtgggtgag gctaccaact acggtgcagt ctactcaaac
    35881 ttattttctg gatttatcaa agataccaac aagctaagcg cctataccgc taagatgttg
    35941 cagacatcgg cagttgttgc tgaaggttca gggcgcacga ttacagacgt tatggagcgg
    36001 attcgctcag gtttactagg gaacaccgaa gcgattgagg acctaggaat caacgtcaac
    36061 gtggctatga ttgagtccac tgaagccttt aagaagttcg caaacggaca gagctggcaa
    36121 cagttggatt accaaaccca gcaacaaatc cgccttatgg ctattctgga acaggctaca
    36181 gccaagtatg gggatacctt gtctaattct gtaaatggtc gtatcagcct atttaagtcg
    36241 ctgatgaagg acgcagcatt gaaccttggt aactctatgt taccgattat caatgccatt
    36301 atgcctgtct tgaactcttt tgctatggtc ttaaagaacg ttactgctaa actcgctgag
    36361 tttatcgctt tgatgttcaa caagaaagca acagtgaaag atggtgttgg tggagcagtt
    36421 ggagacatgg gtaacgccat gaaggatgct gcaggcggag caggagacct tgctgacgca
    36481 gtagacgacg ctggagattc agcaggagga cttgctgaca atcttggaga ctccgccaaa
    36541 aacgctaaga aggccgctaa agagttgcta ggtcttttgg gatttgatga gattaacatc
    36601 ttgcaaaaac caaaagatga cgacgcaggc gggtctggag gcggtggcaa aggtggtaaa
    36661 ggaaagggag gcggtggcgg acctttcaaa gacatcttgc cagaagtcga gttgaccgac
    36721 atggacaaca aattcaagag catttttgat ggtcttggag ataagctcaa agggttgttt
    36781 gacctcttca agaaaggttt tgatgcagca tttagaccag aaggtataga acgcattaag
    36841 actgccttag accaaatagc taagacaatg ggagaaatcg ccactgaccc aagggttgtg
    36901 aatgccttta accgaatggc tgagaaaatt gcttatgctt tagggcaagt gacaggctca
    36961 ataacaacta tcgggctagg tatcggtgtt ttccttgccg aaagtattgc aaatggcctt
    37021 ggaaggcaaa aagaacgcat taccagggcg ctagtcgctt tgtttgataa tattggtaac
    37081 atttccgagg cagtaggaaa catcgctcag gacttttcta gtactttcta cgacgtcatt
    37141 acctcaactg gtgcggttcg tatcggtagc gctattgtgt caactctgtt gagtttgaca
    37201 tctaccattg ttgaagttgg tagtaaatta gcaggaagtt tgtttaaagg ttttgaaaaa
    37261 gtcgttgtga caagcgctcc taaaatttca tcagtcttcc aaagtttatt agatactgtt
    37321 gcgcctgtat ttgagagcat tgaaaggtct gttaacaaat ttggcgatgg cttaagtcgt
    37381 gtttatgatg aacatgtagc ccctgctatt aactctattg ctaatgcttt taacggactg
    37441 attgatatca tacaaatcct ctgggagaat tcttggcaac cttttgctga gtttttatca
    37501 ggagtattcg gtgttagtat tgaaggaatt tcagatttat taggaggtgg ccttttagcc
    37561 actttgggac tattggcgga tgctattaag ttagtggcag atggtttcac cgttttttct
    37621 gactggtgta aagaaaacaa agaacctatc ttggctttga taacaacttg gcaaacgatt
    37681 aatttcttat catgggctga acaagccggg ggacttgcag gagcattcag cttgttaggt
    37741 agtaaggtct ctttgattgt tggagggatt aagaatctag gtcttgctat taaagcattg
    37801 acatttgata agttggtcag ttttggtgaa acaatctatt tgaacacctt atatgcaaaa
    37861 gattttgtgg tcaattcagg taaaacaatt gcacagctag gaaaaactgc tttagaactt
    37921 ggtaaatcag ctctagcatg gactgctcat gcagcgaaaa tgggattagc aaccgcggcg
    37981 gaatttgcac attctgttgc agcaggagtc gctacagctg caacatgggc ttttaatgca
    38041 gcgttagcag ttttgacaag tccaataaca tggattattg cagcaatcgc agctttgatt
    38101 gctatcggtg tcttgctcta ccaaaactgg gacactgttg ttgagtttgc taaaactgca
    38161 tggcaaggac tatgtgattt tattagtggt atttgtcgag ctattggcga atttttcagt
    38221 ggtctatgga caaaactaca agaaatcttt gagccgatag gtcaatggtt tggcgagaag
    38281 ttccagcaag catgggatgc cattgtcaac atcttctctg gtatcggaga gtggttctct
    38341 ggtgtattcc aaggtgcatg ggacgctatc gttaatatct tcactccaat cggctcatgg
    38401 tttggacaac gttgggcaga tgtgactagt gctttggcta atatcggggc atggtttact
    38461 gacatattcc aaaaagcatg gactggtcta acaaacatct ttagcaaact aggtttatgg
    38521 tttggcgaga gatgggcaga tgttacaagt gttcttgcga atgtatcttc ttggtttggg
    38581 aatatgttta ctagtgctta taatgcagtc aagaacgcgt ttagttcaat tggtggcttc
    38641 ttcagcggtg tatggtcaac ggttcaaagc atatttgtca atgctggaca aaaggttggt
    38701 agcgctgtag gtggagcgtt taagagtgcg gtcaatgcgg ttcttggaac gattgaaaat
    38761 gtagtcaatg acttcatcgg aatgattaat ggagttttag gcgttgtcag aaacttacct
    38821 ggtctaggat gggttggtag tgtaagcaca gttagcctcc ctcgtcttgc ccgtggtggt
    38881 atcgtcgata gtccaacaat cgccatgatt ggtgaagctg gtaaagaggc ggtcgtacca
    38941 cttgaaaata caggatttat ccaaacactt ggacgagtag tcagcagtgc ggtagtaaat
    39001 gccatggctg gtattagtcc acaaggtggt ttttctagcg acggcgacat cgttattcaa
    39061 atcgcaggcc atgagttcgg acgggtagct atccaagaaa tcaacaagga acatgaacga
    39121 gcaggtcaaa ccttgctcaa gatttaggag gttaaatggc acaattgaca atcaatgggg
    39181 tggctgtgaa gcctcccaaa tcttttcaag tcggtattca agatatcgat ggagagacag
    39241 ggcgtaatgc caatggcgac atggtgcgtg accgtatcac gaccaaacgc aaactagact
    39301 gtgaatgggg tatgatgact cagggagaaa taagtcagct tttacatgct gtatcatcta
    39361 aattttttga ggtatcttat ccagacccca tggatggcca agtcacaaag actttctatg
    39421 tcggtgatag gacagctcct agctatacct ttactgagaa gcttaaacct tggtctggcg
    39481 ctaaatttaa tctggtagag aggtaagaaa atggacgctt taactagacg acaatttgac
    39541 agagccatgt ttgccaagga aaggacgctg gctattcgtg ttggtgaata tgcttcacgg
    39601 gatatcaaag aggctagttt tgagtatggc tacatcaagg gcgatactta taagcctggt
    39661 ggaacctgcg ctggtagcgg taaaattacc tttaccagta tcattaccac gttcaataag
    39721 ctggataccc tgcaccctga gattggtcta ctggttgggg atacctacca gtgggtcaag
    39781 atgggggaat acttcatcaa cgatattgag attgaccgaa accgcaacac aaccacactt
    39841 gaacttatgg acggtatgtt taagctcaat cgtgagtacg tgacggattt gcatttccca
    39901 gctgaagtac gagaggttat tcaggaaatc tgcctgaaaa caggcattga gttagcgaat
    39961 gactatttcg gaatcagcgc tatgcgttac catatcgagc aagttcctga aggtaagaaa
    40021 ctttcgttca gggatatgct gagcgctatg actcagatga ttgggatgtc ttgcttcttc
    40081 aaccgagaag gaaagatgga aatccgtgat ttgaccgagt ccaacatcac gattaacgct
    40141 gacagttact tcttgcatgg attgaccaag agtgaaatcg agtatcagat agctggtatc
    40201 acttgtaaga cggataagaa gtctctgacg gtcggtatga caacaggtcg gtctttggaa
    40261 cttgataatg tcttcataac ccagagcgct ttaaatgact tgtattacaa actgaaaaac
    40321 ctaacttact atccgtataa tctcaactac caaggacatt tgttacttga ggttgggcag
    40381 tgggtaacca ttcagaccaa caagaaagag acttttaaag ttcctgtctt aagtcagagc
    40441 tttatcttta aaggtggtct gagaggtcgt atcagtgcag atagtaaggc tggaaacgat
    40501 acccagtatt cttacgaggg tacgattacc aagcagatta agcaacaaga tggctttgaa
    40561 gcgaaaatcc aagcgcagat tgaagcagca gataaagatt ttgaccaaaa ggtcgacaaa
    40621 atcaaaaaag actttaacga tcaagtagaa ctggccaaag ccagagctga agaagtcaag
    40681 agagaactgt ctgacactat caatcagcgc tttaatagct ttgacaacgg gccattgaaa
    40741 gaagctaagc gcaaggctga ggaagctttg cgaaatgctg gcgcaagtag ttctcttgct
    40801 caggaatcca agcggattgg gctggattct gttgctagac ttgaagcgtt taagtcgcag
    40861 actacgagcg cacaaacggc tctgtcgggt gacttggatg ttctaaaacg aactatcgca
    40921 aacgatattc gaccgaagca agcacaggct gaagctgaga ttgccaagca agttgaagca
    40981 cttagccgga ctaaaaatga actggatggc gcaagtaccc tgcttgcaca ggaagctaag
    41041 cggattgagc tggattctgt tgctagactt gaagcgttta agtcgcagac tacgagcgca
    41101 caaacggctc tgtcaggtga cttggatgtt ctaaaacgaa ctatcgcaaa cgatattcga
    41161 ccgaagcaag cacaggctga agctgagatt gccaagcaag ttgaagcact tagccggact
    41221 aaaaatgaac tggctggcgt gaagtcagcg caagcgacgt atgaggagac gacgactcgt
    41281 agactgtcag aactgaccaa cttggccaat ggtaaagcca gcaagtcaga actcacgcag
    41341 acagctgagg agctagctag tcggattgcg agtgtgcagg catccggtcg aaatctattc
    41401 ttgaactcac tattcaagca ggatatttca aaaacaggaa tttggacaac gagtacatat
    41461 acggctacta tcgatagcga aagtaagtat cttggatata acgctcttaa aattataggt
    41521 ctgaatccat ctggccgtga tggagggaat cccaaggtta cttatccagt tctgggtcaa
    41581 ttcgggaaag taattcccgg aagtacgact aatcaagatg taaccattag tttttatgct
    41641 aaggcaaata aaaatggaat aatgctaaga tctcgattag ggaatatcgg atataaaact
    41701 ggaaatgtga cattgtcgac agaaattaaa cgatatgttg tccatattcc aaaaggttgg
    41761 acaaacgaat ccaagcagac cacaaatgaa tggttgttca atttcaacca ggaaggaacc
    41821 gtttggattt ggatgccgaa gtttgaaata agcgatgtag atacttctta ttcagaagct
    41881 cctgaagata tagaaggtca gatttcaaca gttgaatcga cctttaaaca acgagtcaac
    41941 tcgctcgaag ctggtgtgaa tcgtctgact gaaggcctta gaaccaaagc cgatatcagc
    42001 gcactcaacg tgactgctga aaatatccgg caatctgtga agagtcttga gacagacacg
    42061 cagaacaagc taaatcagaa gttgagtcag gctgaatttg aggtgcgagc cggctctatc
    42121 cgtcaggaaa tcctgaacgc aaccaaggat aaggcagata agactttagt tgtatctgaa
    42181 gctgggaaat tgcgtgaaga attttcaaaa atgaaggtgg gaggccggaa tctatggata
    42241 aaatccaaga cggttggagc tgtaattgaa aaattacctg aaaaccatgt cacaggtcaa
    42301 aaagaatgtt ataggttaga gaacaactct actttaacgt tcaaccttga accagatttc
    42361 agctcaaggt tgtatcaaaa agttactttt agcgcttgga tcaagtacga aaatgtagtc
    42421 caaggtcgaa acttttggaa tgtatttaat tgcttcaaac attatctttt tagaaaaaat
    42481 agtgagaccg gagtacagag tggtccagat tatgctacgc ttggtatgta taaaggttcg
    42541 gcagattgga aatatattac attcacttat gactactctg aaaaaacaaa ttttgatcaa
    42601 ttgaagacat cattgcgatt caatcttgaa ggtgctacaa gcggtacagc ttgggtaaca
    42661 ggaatcaagg ttgaaatcgg tagtgtggcg acggactggt caccagcacc agaagacgga
    42721 gaaaatgagc ttttagtcgc taaaaccgag ttcaagagga cagctgatgg cctatctact
    42781 aagatggcag cagttgagag ctatgttggt caagacggtc agcgacagga agccctacag
    42841 cgctatactc gtgaggaaag cacgagacaa gcgacagcag tccgtgagct ggtcaatcgt
    42901 gatttcgttg gtaaggctac ttatcaagaa gatgttaagg gtatcaatca gaggattgaa
    42961 gctgttaaaa ctagtgcgaa taaagacatc gctagtcaaa tcgctagcta tcgtcaatct
    43021 gtagatggta agttcacgga tatttcaagt cagataacta cttataagca agatgtgggc
    43081 ggtcaaatca gtggtctatc aaatagactt acaagcagtg agcaaggaac cactactcag
    43141 atttcaaata tttcaaatcg gataaacagt aataagcaag gcacagataa tcagatttca
    43201 aatttaaaga ctcaggtcgc tacaaacaag gataatgctg aacgacaaat gggtagaata
    43261 tctgatcagg tttctgcaaa caaagcgaat gctgatagtc aatttgcgaa tgtgaccaat
    43321 caactagcgc gaaaagtaga gactactgac ttccagcgtg ttaaggaaac cagtaaactt
    43381 tacgagcgaa ttttgggcaa tactgaaaat ggaattgcgg ataaggttgc tcgcatggct
    43441 ctgactaatc aactgtttca ggttgaggtt gggaaatata gtgtaagcgg ccctaacctc
    43501 attaagaata gtgattttaa aaatgctacg aatgaatggg gctcaactca aaatttagga
    43561 agattggtta agcatagctt ttatcacaac gggcagaaag accttatgcg tttaagtaat
    43621 gcaactaaaa acgaaaactt tttgtatagt caccgtttta atcttgaacg aaatactgac
    43681 tatgtactga attttagagg atttaacaac agtgctctcg caagctatga tgtttatatt
    43741 ttgggacgaa gagcaggcga gagcgatgga ttcacaatcg ttaagaaagt tgttagcagc
    43801 aagaaactat ctacctctag atgcgaagat gtctcagtaa cttttaattc cggagaaatg
    43861 gataatgctt acattcgttt tgataacaat ggctcatcat caggaacagc tgatttgtat
    43921 attacagaag ttgacttgta caaaggttat aaacctagaa catggcaacc acatccagaa
    43981 gatgcagtcg cagatgcgaa taagaagctt gaagcaacgc aaacaaaaat gactcaacta
    44041 gctggctcat gggtagttga aaacatcaac tcggctggag atatcatctc tggaatcaat
    44101 cttggcgcca atggacataa ccgcttcgtt gggaaattga cccacatcac tggagagacc
    44161 ctgattgaca gagcagtcat caagtctgcc atggttgata agctgaaaac gggcaatttt
    44221 gaagctggtt cggtcacgac tacgatatta gacgctgaag cggtaactgc tgagaagttg
    44281 aaagttgacg atgcgcttat tagaaaatta actgcaaatg atgcttttat tgaccgactg
    44341 acatctaaac gtatcttctc tactaaggtt gagtccgtca tttctagttc aaccttccta
    44401 gaagcctatc aaggtcgaat tggtggattc acacttggtc aatttgacca gggtggcggt
    44461 cgctggattt caggtgtcaa tcagttctct gttggtatgg ggaatggtgc cgggcatgga
    44521 gtccggacag ccttctgggc gaactgggga aataattgga actatgccgg acctaaagca
    44581 tggaacgtca atactgatgg gaaaatgtac tgtaggaatg aagtcggttt ttatgatcaa
    44641 gtggattttt cgaattcatc gagagcaaac ttctatggga atactacttt ttctcgttct
    44701 cctgtgtttt caaatggtat cgaacttgga agtaaagatg tgcttggtga tggttggaat
    44761 cccaaaggcg gaaggaatgc ggttgtttgg tggaatcagg tcggtagcgg tagcgtgaag
    44821 tattggatgg aacaaaaatc agacagacgc ttaaaagaga acatcacaga tacagctgtg
    44881 aaagccttgg acaaaatcaa cagattaaga atggttgcat ttgatttcat cgaaaataag
    44941 aaacatgagg agattggtct aatagctcaa gaggctgaaa ccatcgttcc aagaattgtc
    45001 tcacgagatc ctgagaatcc agatggctat ctgcatattg actataccgc tttagttcct
    45061 tacttaatca aggctattca agaattaaat caaaaaatag aaaaaatgga gaaaacaata
    45121 gcatgaataa caacatgttg accaatatcg cactttaaag caattcagga gcttgctctt
    45181 gaaaatagaa aacgaacaca cagattggag aacttagaaa atgaacacag aacagcttaa
    45241 ccaagcctta caaatgacaa ttagtgaaat gtcaacaact tcaacaaatt cgatgattac
    45301 aaataatatc ttgagtattc agttggatga gcaaagggaa gggaatcaaa gacttcaagc
    45361 acgagtggat gagctggaag ctctgcttga tgaacaaact aaaccagcag acaaaggaga
    45421 atagacatgg cagaaacaaa tcaaaacaca gataacttac tagaccttac aaaaatcaca
    45481 gaaccatttg atcttgcgag tgctttgcgc tacatgaaag aaaatggaga gttcattcgt
    45541 tgcaagaatg taagcgatga cttctatatg tatcgtgatg ttcaaaaacg tcctgtgatc
    45601 gtaaatggcc gtcgccaact caaggatgtt gaaaccgttt gggcgttcaa ccagtggggt
    45661 ggtacaatcg caacaatcaa cgtcgccgtt ctgttgaatc atgaattcta tatcatgaaa
    45721 tttgatgcag agggcaatcc tgactggacg gatccaacgg taaaacctaa agaataggag
    45781 gtgtgtatgc caattgaaga agctgaaaaa atcgctcaaa gtcaggtagc ttgggcgatt
    45841 ttgtttatct tgcttttctt tattatcatt cgatatctta tcaagacttc ggacaagcga
    45901 gagaagaaga ttatggattt gcacgagcaa tcaaaggccg actctaatag acgagaagag
    45961 cgtttgatga ctcacctaga aaagaccact acagaattaa ccacaatcac tcacgcggtc
    46021 ggagacattc aaaaagaaat ggttcgcatg aacgaccgca tggaagaaat cgaaaaagga
    46081 gaataacaaa tgcaacaaat tactgaaatc attactaatg gagcaatcag catccttgtt
    46141 attttggctg gtatcgcagt caaggcagtc aaggactacc tggttcaaaa aggtggagaa
    46201 aagaccatca aaatcgttga aatcttggcc aaaaatgcag taaatgccgt tgagcaagta
    46261 gctgctgaaa ctggctacaa gggagatgaa aaactggcac aggctcgcgc taaagtccgt
    46321 gctgagctta caaaatacaa tattagcatg actgacaaag acttagacac cttcgtagag
    46381 tcagcagtga agcagatgaa tgacgcatgg aaaggacgat agggaatgga tatcgataga
    46441 aacagactac gtacaggctt gccacaggtt ggggtgcagc cttatcgaca agtacacgcc
    46501 cattcaacag gcaaccgtaa ctcaaccgta cagaatgaag cggattatca ctggcggaaa
    46561 gacccagaat taggtttttt ctcgcacgtt gttgggaacg gtcgcatcat gcaggtagga
    46621 cctgtgaaca acggaagttg ggatgttggg ggcggttgga atgctgagag ttacgcagcg
    46681 gttgaactga ttgaaagcca ttcaactaaa gaagagttca tgacggacta ccgcctctat
    46741 atcgaattgc tacgcaatct agcggacgaa gcaggcttgc cgaagactct tgatacagac
    46801 gacttggcag gtatcaagac gcatgaatac tgtaccaata accaaccaaa caaccactca
    46861 gaccatgtgg atccatatcc atatcttgct aaatggggca ttagccgtga acagtttaag
    46921 caagacatcg aaaacggctt gagagctgca acaggctggc agaaaaatgg cactggctac
    46981 tggtacgtac actcagacgg ctcttatcca aaagataagt ttgagaaaat caacggtacc
    47041 tggtattatt tcgatggctc aggctatatg ctttcagacc gctggaagaa gcacacagac
    47101 ggtaattggt actactttga ccaatcaggc gaaatggcca caggctggaa gaaaatcgct
    47161 gagaagtggt actattttga tgtagaaggt gccatgaaga caggctgggt caagtacaag
    47221 aacacttggt actacttaga cgctaaagaa ggtgctatgg tatcaaacgc cttcgtccag
    47281 tccgcagacg gaacaggctg gtactacctc aaaccagacg gaacactggc agataagcca
    47341 gacttcacag tagagccaga tggcttgatt acagttaaat aaatagaaag gaaactttct
    47401 aaattgttct ttcaccgcag gctcaggctt gcggtttttt tgttttaaaa aaggggcaaa
    47461 aaaggggcaa aagtgtcgta aatctctgta aaatgatgta aaaacattta tttaaaagct
    47521 caaaatatag ctgttttaaa aggtattgta agatatagta aaacgatgta aaggtatttt
    47581 taaatgcgga tgaattataa aaccacgaat cctatgtgac tcgtggttct tttttataaa
    47641 ctggtagagt gttttggttg tactttttgt tcagggtcaa tgtagttgat agcgttgttg
    47701 acagcagttg gagcttcccc tagacctgtc gcaatcagat caatttttcc gtcatagtag
    47761 cagcagtcac cgatagcata gatacctgct tggctggatt cttgtttgct gttgacgata
    47821 atcttgtgac ggttgaggtc gagcccccag tttttaaggt taccgacaga agatttgaaa
    47881 ccatagttga caaagaggtg gtctaggtca atggtttcag tttcatcaga tttgactttt
    47941 gtgatttcaa gtttatcaag cgtttttcca tctccaagga gttggctagg gacgaatggt
    48001 gtcttgatgg ttacagatga ttcttgcaag gcttgaacac tgtgttccaa ggcacggaaa
    48061 ttatctctgc ggtgaacaag ggtagttggt gcgatttttt caaaagccaa agtccaatcc
    48121 acagccgagt ctcccccgcc aagaatcgtc actttcttac cagcgtattg ctgaatgtta
    48181 gaaacgtggt agtggatatt ttcatagccc tcaacacttt caagttccag cggacgtggt
    48241 ttgaaggcac cgccacccat agcgatgata actgttttag tcaggtgact tcctttagaa
    48301 gttgtgatgg caaattcttc ttcttgtttg tcaatctcaa gaaccgtttc attgagatga
    48361 ataggggtat caaatccatt tagctgttca atcaagcggt tagtcaactc ttctccagtc
    48421 aggtttggga agcctggtac gtctaggatt tccttttcag ggtagagaat agcaggttgt
    48481 ccacctagct ggggaagaga gtcgatgatt tgaaccttgg cttggcgtag gtgggcataa
    48541 aaggctgcaa aaagcccgac aggaccacca cccacaatgg taatatcata gagttgagac
    48601 atagtttctc ctttgttttt tctagtcagt ttattttatc atatttttgt tcaatgtaaa
    48661 atggactagg atagggaaaa aaatgccaga aaatggtata ataggacgaa agtgttttga
    48721 tagggaggat atcagggatg aattttcaac aattatccaa tctgcaatat tggaccagtt
    48781 tgtttgcaag tccatggacg atagctatca atctgattga tattttgatt gttgcttata
    48841 ttttatacca ttttacaaaa gctattgcag gaaccaagat tatgattttg gtacgtggag
    48901 ttttggtgtt tattttagct caaatccttg caaatatgat tggtttgact acgatttctt
    48961 ggttaatcaa tcaaattatt acttatgggg ttattgcggc ggttgttatc ttctctccag
    49021 agattcggac tggtttggaa cgtttgggaa gagcgacaga ttttttttcc aatgccccta
    49081 ttagtgctga ggaacagatg attcgtgcct ttgttaagtc tgttgaatac atgagtcctc
    49141 gtaaaatcgg ggccttggtt gctattcagc gtgtacgtac cttgcaggag tatatttcga
    49201 caggaattcc cttggatgct aagatttctg cagaacttct cattaacatt tttattccca
    49261 acactcccct acatgatggt gcggtgatta tcaaagaaga acgtatcgct gtgacgtctg
    49321 cctatctgcc cttgacaaaa aacacaggga tttccaagga atttgggacc agacaccggg
    49381 cggctatcgg tttatcagaa gtctcagatg ccttgacttt tgtcgtatca gaggaaacgg
    49441 gaggaatttc gataacctat aatggaaggt ttaagcacaa cctaacactt gatgaatttg
    49501 aaacagaatt acgtgaaatc ttacttccaa aagaggaagt gggtcttagt tttaaagaac
    49561 gattgctagg aggatggaaa catgaaaaaa aatagtttat atatcatatc ctcactcttt
    49621 tttgcttgtg tcttatttgt ctatgctacg gcgacgaatt ttcaaaacag taccagtgct
    49681 aggcaggtaa aaacggaaac ctatactaat acagtaacaa atgtccctat tgacatacgc
    49741 tataatagtg ataagtattt tattagcggt tttgcttcag aagtatcagt ggtcttgact
    49801 ggtgcaaatc gcctatcgct agctagtgaa atgcaagaaa gtacacgtaa attcaaggtt
    49861 actgctgacc taacagatgc cggtgttgga acgattgaag ttcctttgag cattgaagat
    49921 ttacccaatg ggctgaccgc tgtggcgact ccgcaaaaaa ttacagtcaa gattggtaag
    49981 aaggctcaga aggataaggt aaagattgta ccagagattg accctagtca aattgatagt
    50041 cgggtacaaa ttgaaaatgt catggtgtca gataaagaag tgtctattac gagtgaccaa
    50101 gagacattgg atagaattga taagattatc gctgtcttgc caactagcga acgtataaca
    50161 ggtaattaca gtggttcagt acctttgcag gcaatcgacc gcaatggtgt tgtcttaccg
    50221 gcagttatca ctccgtttga tacaataatg aaggtgacta caaaaccagt agcaccaagt
    50281 tcaagcacat caaattcaag tacaagcagt tcatcggaga catcttcgtc aacgaaagca
    50341 actagttcaa aaacgaatta aaaatagaaa aggattttat aacaatgggt aaatattttg
    50401 ggactgatgg agtccgtgga gaagctaacc tagaactaac accagaatta gcctttaaac
    50461 taggacgttt tggaggctat gttcttagtc aacatgaaac ggaagcgccg aaagtctttg
    50521 taggacgtga cacacgtatt tcaggggaaa tgctggaatc ggccttggtg gcaggtctcc
    50581 tttcagtagg gattcacgta tacaaacttg gtgtccttgc aacaccagca gtagcttact
    50641 tggttgaaac tgaaggagca agtgccggtg tcatgatttc tgctagccac aacccagccc
    50701 ttgataacgg aatcaagttc tttggcggtg atggcttcaa actagatgat gaaaaagaag
    50761 cagaaattga agccttgcta gatgctgagg aagacactct tcctcgtcca agtgcagaag
    50821 gcttaggaat cttggtagat tatccagaag gcttgcgtaa gtatgaagga tatcttgttt
    50881 caactggaac tcctcttgat ggaatgaagg ttgccttgga tacagctaat ggagcagctt
    50941 ctaccagtgc ccgtcaaatc tttgcagacc ttggtgccca attgacggtt atcggggaaa
    51001 caccagacgg tcttaacatc aaccttaatg ttggttcaac acatccagaa gcccttcaag
    51061 aagtggtcaa agaaagtggg tcagctattg gtttggcctt tgatggagac agtgaccgct
    51121 tgattgctgt tgatgagaat ggtgacatcg tcgatggtga caagattatg tacatcatcg
    51181 gaaaatacct ttctgaaaaa ggacaattgg ctcaaaatac aattgtgaca actgttatgt
    51241 ctaaccttgg tttccacaag gccttgaatc gcgaaggtat taacaaggca gttactgcag
    51301 ttggtgaccg ctacgttgtt gaagaaatga gaaaatcagg ctacaacctt ggtggtgaac
    51361 agtctggtca cgttatcttg atggattaca ataccacagg tgatggtcaa ttatcagcag
    51421 ttcaattgac taaaatcatg aaggaaactg gtaagagctt atcagagttg gcggcagaag
    51481 taacgattta tccacaaaaa ttagttaata tccgagtgga aaacgtcatg aaggaaaagg
    51541 ccatggaagt gccagctatc aaggccatca tcgagaagat ggaagaagaa atggcgggga
    51601 acggccgtat ccttgttcgt ccaagtggaa cagagcccct cttgcgtgtt atggcagaag
    51661 cgcctacaac agaagaagta gactactatg ttgataccat cacagatgta gttcgtgctg
    51721 aaattgggat tgactaaatc ctagaaaact agatgaaaat aaaaaattat gatacaatag
    51781 cttataatat tgtagccgat ggagaaagac atgaatctta aacgtgaaca agaatttgtt
    51841 agtcagtatc attttgatgc gcgtaatttt gaatgggaaa atgaaaatgg agctcctgaa
    51901 accaaggtgg atgtgaattt ccaattgctc caacatgacc aagaaaatca agtgacttcc
    51961 ttgattgtca tcttgagctt tatgattgta tttgataagt ttgtcattag tggaacaatc
    52021 tcacaagtaa accatatcga tggccgtatt gtcaatgaac caagtgaatt gaaccaagaa
    52081 gaggtggaaa ccttggctcg tccatgtttg aacatgctca atcgtttgac ttacgaagtg
    52141 actgaaattg cattagactt accaggaatt aatttggagt tctaatatga aattagctgt
    52201 tttcacagat tcctctgctt atctcagtgc agagaccttg caaagagaag acttgtttgt
    52261 cttggatatt cctgtcaata ttgatggtga ggaatatgtc gaaggcatca atctgtctgc
    52321 tgaggaattt taccaaaaaa tggctcaggc ttctgaattt cctaagacca gtcaaccaag
    52381 tattgccaag ttagatgaaa tcttaacttc gctcaaagaa caaggctata cacatgcctt
    52441 ggggcttttc ctatcttctg gaatttcagg tttttaccaa aatatccagt atatggtcga
    52501 tgactatgag ggcttaacca ttgctttccc agacactttg attacaagtg ctcccctagg
    52561 catcatggtt gaaagcgtct ttaattggcg tgatcagggc gatgattttg ccagcattca
    52621 ggataagcta gccattcaaa tcagccgtac gtcagccttt atcatggtag atgacttgga
    52681 tcatttggta aaaggtggac gcctttcaaa tggggctgcc attttgggca atttgcttag
    52741 cattaagcca atcctttatt ttaacgatca aggtgtgatt gaagtttacg aaaaagttcg
    52801 tactgaaaag aaggccacca agcgcttaat tgaaattatc aaggaaacaa cggcttcagg
    52861 tcaataccgg gtcattgtca ttcatgggaa tgctcctgaa aaggctgaag aattgcgtca
    52921 gcacttgctt gattttggct tgggttcgga tgtttcactt gctacatttg gtagtgtcat
    52981 tggaacgcac ctaggagcag gaagtattgc tctgggttat attccagtga tttagttggc
    53041 gcttctaggc tagttaagat gccttgtatc ttagaaattg aacacggact acctgcctct
    53101 tgaaaaaaga tgcctgtctt gcctttcgtg gaaagtcagt gccattccct atttttcaga
    53161 ggcagctaag gtcctttgta tcttgataat tgaacacgcc tggaaccctg tgtgaaaaag
    53221 atagttcttc caagaagtag acacttcttg attggaattc ctattttcac tttgtgttct
    53281 tacggacttt gtatcttaga caggagtaga gatgagtatt cgagtaatta ttgccggttt
    53341 taagggaaag atgggccagg ctgcttgtca gatggtattg actgatccag acttggactt
    53401 ggtggcagtt ttggatcctt ttgagtctga gtcagaatgg cagggtattc ctgttttcaa
    53461 ggataaggct gatttagctg gttttgaagc ggatgtctgg gtagatttta ctactccagc
    53521 tgttgcctac gaaaatacac gttttgctct tgaaaatggc tttgctccag tagttggaac
    53581 gactggtttc acgagtgaag aaattgcaga gctaaaagaa ttttctcgtg cccaagactt
    53641 gggtggcctg attgccccta actttgcctt gggtgctgtc ttactcatgc aatttgcgac
    53701 gcaggctgcc aaatatttcc caaatgtgga gattattgag ctccatcatg acaagaaaaa
    53761 ggatgctccg agtggaacag ccattaaaac agctgagttg atggcagagg ttcgagagtc
    53821 cattcagcaa ggtgcagcag atgaggaaga gctgattgct ggtgctcgtg gtgctgactt
    53881 tgatggtatg cgcatccact cagttcgttt gccaggcttg gtagctcatc aggaagtcat
    53941 ctttggcaat cagggagaag ggttgaccct ccgtcatgac tcctatgatc gcatctcctt
    54001 catgacagga gtcaatttgg gaattaaaga agttgtcaag cgtcatgagc ttgtctatgg
    54061 attagaacac ttattatgag attaatgcaa atgccttctg aatttcagaa ggctttacca
    54121 gtattagaaa aaattaaaga agcaggcttt gaggcttatt ttgttggggg ctctgttcga
    54181 gatgcccttc tccatagccc tatccacgat gtggatattg cgacgtcttc ttatccagaa
    54241 gagaccaagc agatttttcc gcgaacagcc gatatcggaa tcgagcatgg aaccgtcttg
    54301 gtcttagatg gggatgagga gtatgaggta acaacctttc ggacagagga tgtctatgtg
    54361 gactatcgca gacccagtgc ggtttccttt gtgcgctcgc tagaagaaga cctcaaacgc
    54421 cgtgatttca cagtcaacgc ctttgccttg gatgagacag gagaaatcgt tgacttgttc
    54481 catggtttag aagatttgga aaagcaagtc ttgcgagcag ttggagtggc tagtgagcgt
    54541 ttcaacgaag atgctttacg gattatgcgt ggtttccgtt ttcaggctag tcttggtttt
    54601 gcacttgagc cagaaacatt taaagctatg aagaccttga cgccgctttt ggagaaaatt
    54661 tctgtagagc gtaccttcgt cgagtttgat aaactcttgc tggctccatt ttggagaagg
    54721 ggcttggctt ccatgattga gagtcaagct tatgactatc tccctgatat agcatctagc
    54781 caggacaagc tcaacagact gtttgatttg gagactgatt ttacttttga atcctctgaa
    54841 caagcctggg cggctttact atgggctttg gagattgaaa atgcgcagtc atttttgaaa
    54901 tcttggaaga cctcacgcca gtttgccaag caagttcagg atttgctgat tattttggct
    54961 ctgcgtgaaa atggagaatt gagtaagcgt gattgttatc gctttgactt ggatttactt
    55021 ttacaggctg aaaatcttcg tcaagctcaa ggaaaagaag tcaacccaca agtcattaaa
    55081 gaaacctacc agagcttgac tattcatgat aagaaagaaa tccaaatcaa cggcggtatt
    55141 ttgatcaagg aatatggcta tcagccaggc ccagacttgg gagagatttt aacagagatt
    55201 gagtttgcca ttgtcgatgg agaattggag aataatcgtg aagccatcca tgcttacctg
    55261 agggagaaaa aatgagtgat tttatcgttg aaaaactaag taaatccgtt ggtgacaaga
    55321 ccgtttttag ggatatttcc tttattatcc atgacttaga cagaattggt ttaatcggtg
    55381 tcaatgggac tggcaagacc acccttttgg acgtcctttc tggtgtttct ggatttgatg
    55441 gggatgtcag tcctttttca gctaaaaatg attaccagat tggttacttg actcaggatc
    55501 ctgattttga tgatagaaag acagttttgg atacggttct atctagtgaa ctcaaggaaa
    55561 tccagctcat tcgtgagtat gaattgatta tgctcgacta tagtgaggac aagcaggcgc
    55621 gtttggaacg tgtcatggca gagatggact ctctccaagc ttgggaaatc gagagtcagg
    55681 tcaagaccgt tcttagcaaa ttgggcattc aagacttatc tactcctgtt ggggaattgt
    55741 caggtggtct gagaagacgg gtacagttgg cacaagtctt acttggcaac cacgaccttt
    55801 tgcttttgga tgagccgacc aaccatctgg atattgcgat tattgagtgg ctgaccctct
    55861 ttttgaaaaa ttctaagaag accgtccttt ttatcactca cgatcgttat ttcttagacg
    55921 ctttgtcaac acggattttc gagttggagc gagcaggctt gaccgagtac cagggaaatt
    55981 accaggacta tgttcgccta aaggcggaac aggatgagcg cgacgcggct cttcttcaca
    56041 aaaaagaaca actctacaaa caagaattgg cctggatgcg cagacaaccg caggcgcgtg
    56101 cgaccaagca gcaggcccgt atcaatcgat tccatgatct gaaaaaggaa gtttcaggca
    56161 gtagtgctga gacagacttg accatgaact ttgaaaccag tcggattggg aagaaagtca
    56221 tcgagtttca ggctgtttcc tttgcctatg aaaacaagcc tattttgcaa gattttaatc
    56281 tcttggtgca ggccaaagac cgtatcggaa tcgttgggga caatggtgtt ggaaaatcaa
    56341 ccctgctcaa cttgattgca ggaagtcttg agccaactaa aggacaagtt gtgattgggg
    56401 aaactgttcg catcgcctat ttctctcagc aaattgaggg tttggatgaa agcaagagag
    56461 ttatcaatta cctgcaggaa gtggcagaag aggtcaagac cagtggcggt tctacgactt
    56521 cgattgcaga gttgctggag cagttccttt tcccacgttc gacgcatgga accttgattg
    56581 agaaattgtc agggggtgag aaaaaacgtc tttatctcct caaactgctt ttggaaaaac
    56641 caaatgttct tcttttagac gagccaacca atgacctaga tattgcaact ttgacagtct
    56701 tagagaattt cttgcaaggt tttgcaggtc ccgttttaac agtcagtcac gaccgctatt
    56761 tcttggataa ggtagcgacc aagattctcg cttttgagga tggcaagatt cgtcctttct
    56821 ttggtcatta caccgactat cttgatgaaa aagcttttga aacagatatg gccaatcaag
    56881 tgcaaaaggt cgaaaaggaa aaagtggtca aggttcgaga agacaagaaa cgcatgacct
    56941 accaagaaaa gcaggagtgg gcaagtattg aaggtgatat tgaaaccttg gaaaaacgta
    57001 tcgctgctat tgaagaggaa atgcaggcta acggctctga ctttggtaag ctgactactc
    57061 tccaaaaaga attggatgag aaaaatgaag cactccttga aaaatacgaa cgctatgagt
    57121 atctcagtga atttgatagt taagactatt cgaaaatcaa agtgcaaact atgtcggctt
    57181 cacattgccg actcaagtac agcctgtgac cggcttccta atttgcactt tgatttttat
    57241 tgagtataaa agaatagaaa aatcccgtct catgaaagga tttctctatt cttttttggt
    57301 ttcttgatga aagatatttt gccaggtttc gtggcgacgc cagatactgg tatggatgat
    57361 accatctaac tcatagcaga tgagtttggt tttttgactg atggaagtaa tttgaatgtc
    57421 ctttatagca gaatttaact cttttttggt cttataagcc tctttatcca tctgctctcc
    57481 atcttggcga atatagacaa aatcatcagt caagagttct tctagttggt ttccttggtc
    57541 aatcaattgt tcacgcataa gcaatttttt atagacattg tctaaaattt catcctcagg
    57601 gataggtgct ggttcgatat ggacatcggt atcaaagacg ccaaaacgct cctccagcat
    57661 agactcgacc tgatccgcga tttcatggct ttcaaaaaca gacaagtcag gattcatctc
    57721 tagtgtaata tccaggtaga tgttgctacc gtaggtgcga cctctttgcg atttgacctt
    57781 gctgattttg ggaatttcca tgatagcctt ttggtagtcc tcgagcaggc ggtcgtcaaa
    57841 gccatctgaa agactaaagg aagactcgat gaagatatca taggcagtct tcaagataaa
    57901 gaaagtgatg atgatagcaa ccagtttatc cacaatcgga taattgaaac tactagctag
    57961 gatggcaatg gcggttccaa gtgaggtaac agcgtcagaa agattgtcct tagcagctgc
    58021 cttcagcgcc ttggagttgg atttcttact gaggcgagta ttgtagagat agaccacaaa
    58081 cataatcgct gcagaaatga ttcctagagt tgcaccaaga ggatcaatga ccgtttcttc
    58141 ccgactgaga atcttttgaa tggtatctct tagaacatcg aaaccgacat agaacatgat
    58201 gatagaagtg atcaagcttg ccaaatcttc aatcttccaa tgaccaaaac ggtggtcacg
    58261 gtctgcaggc tggcgcgcca tccgaatccc gattaagagg gccacatttc caatgatgtc
    58321 cgatacgtta ttaaaaccat cggccaccaa actggatgaa tgaaggagat gaccagctgc
    58381 taatttagct gcagacaaga tcaaataggt cgaaatactg ataatggctc cacgctcagc
    58441 taacttgaga tttgagatag attgcttcat tcaacttcct ttctagtcac atagcattct
    58501 accattatac tggttttcaa ggaaaaattc aaataaggca gtttttactc tttgaaaact
    58561 ccccaaaatt tggtataatg gtactactca agggagtagc tggcagaaac ctgtgatagt
    58621 gtcgtcattc cgaattttat gctgaaaagt atgctttccg gccctatctt aaacagcgag
    58681 acttgttatg attaacaggt ctctttttgt ttgtcgtgaa aagatatgac agaaagagag
    58741 tctgttttgc acacaatgtc aaggaggaga cacatgtcaa aagaacaaaa acgccaagcg
    58801 ttttatactc agagccctga agaggtcttg caggctgtgg atgcgaccga gcaaggtttg
    58861 tcatcaagtg aggcggaaaa gcgccttgcc gaatttgggc acaatgaact cgaagaaggc
    58921 gagaaacgat caatcttggt caaattcatc gagcaattta aggatttgat gattatcatc
    58981 ctagttgcgg cagcaatctt gtcagtcgtg acttctggtg gggaagatat cgcagatgcc
    59041 attatcatcc tagctgtggt tatcatcaac gctgcctttg gtgtttacca agaaggaaaa
    59101 gctgaagaag ctattgaagc cctcaaatcc atgtctagtc cagttgcccg cgttcttcgt
    59161 gatggacaca tggcagagat tgactctaaa gaattggtac caggcgatat cgttgccctt
    59221 gaagcaggtg acgtggtacc agcggaccta cgtttgatag aagccaactc tcttaaaatt
    59281 gaagaagcag ccttgacagg tgaatctgta ccagtcgaaa aagacttgtc agtcgagctt
    59341 gcgacagatg ctggtattgg tgaccgtgtc aacatggcct tccaaaactc aaacgtaacc
    59401 tatggtcgtg ggatgggtgt tgttgtcaat acaggtatgt acactgaagt tggtcatatt
    59461 gctggtatgc ttcaagatgc ggatgagact gatacaccac tcaaacaaaa cttgaacaac
    59521 ctttctaagg tcttgaccta tgctatcttg gtcattgccc ttgttacttt tgtagtgggt
    59581 gtcttcattc aagggaaaaa tccacttggt gagttgttga cttctgttgc ccttgccgtt
    59641 gcagccattc cagaaggact tcctgctatc gttaccatcg ttctttctct tggtactcaa
    59701 gttttggcca aacgacattc catcgttcgt aagttgccag cagttgaaac acttggttca
    59761 actgaaatca tcgcttctga taagactggt acgctgacta tgaacaagat gacagtcgaa
    59821 aaagtcttct acgatgcggt tctacatgac tcagctgatg atattgaact aggtcttgaa
    59881 atgccactac ttcgttcagt tgtcttggcc aatgatacga aaatcgatgt ggaaggtaac
    59941 ttgattggtg acccaaccga aacagccttt atccaatatg ccttggacaa gggctatgat
    60001 gtcaaaggtt tcttagagaa atatcctcgt gtagctgaat tgccatttga ctctgaccgt
    60061 aagctcatgt caacagttca cccattgcca gatggtcgtt tccttgtagc agtcaagggt
    60121 gcgccagacc aactcttaaa acgttgtctt cttcgtgata aggctgggga tattgctccg
    60181 attgatgaga aggttacaaa tctcattcat acaaacaatt ctgaaatggc tcatcaagcc
    60241 ttgcgtgtcc ttgcaggtgc ttataagatt atcgatagta ttccagaaaa tctcacttct
    60301 gaagagcttg aaaatgattt aatttttact ggtttgattg ggatgattga ccctgaacgt
    60361 cctgaagccg ctgaggctgt tcgtgtggct aaggaagcgg gaatccgtcc aattatgatt
    60421 acaggtgacc accaagacac agcggaagcc attgccaaac gtttgggaat cattgacgca
    60481 aacgatacag aaggtcacgt tttaactggt gctgaactca atgaactgtc agatgaagaa
    60541 tttgaaaaag tcgttggtca atactctgtt tatgcccgtg tgtctccaga acacaaggtt
    60601 cgtatcgtca aggcttggca aaaacaaggt aaagtcgttg ccatgacagg tgacggtgtc
    60661 aatgacgcgc cagctctgaa aacagccgat atcggtatcg gtatgggaat cactggtaca
    60721 gaggtttcta agggggcttc tgatatgatt cttgcagatg ataactttgc gactattatc
    60781 gtcgcagtgg aagaaggacg taaggtcttc tcaaacattc aaaagactat tcagtaccta
    60841 ctttctgcta atactgctga agtattaacc atcttcctat caaccttgtt tggttgggat
    60901 gtcttacagc cggttcatct tttgtggatc aacttggtaa cggatacctt cccagctatc
    60961 gctcttggtg ttgaacctgc agaacctggc gtcatgaatc ataaaccacg tggacgcaag
    61021 gcaagcttct tctcaggtgg tgttttgagt tctatcattt atcaaggtgt actccaagca
    61081 gctcttgtta tgagtgttta tggccttgcg attgcttacc cagttcatgt gggtgacaat
    61141 catgctattc atgcagatgc cctaacgatg gcctttgcaa cccttggttt gattcagctc
    61201 ttccatgcct acaatgtcaa gtctgtctac caatccatct tgacagttgg cccattcaag
    61261 tctaagacct ttaactggtc catcttggta tcctttatcc ttctcatggc aacaatcgtt
    61321 gtagaaccgc ttgaaggaat cttccacgta accaaactag acttgtcaca atggggaatt
    61381 gttatggctg gaagcttctc aatgattatc atcgtcgaaa tcgttaagtt tattcaacgc
    61441 aaactcggtt ttgacaagaa tgcgatttaa gggaggtttc ggatgtcagc atatcaatta
    61501 ccgaccgtat ggcaggatga agctagtaat caaggagctt ttacggggct aaacagacca
    61561 acagcaggtg cccgtttcga acaaaacttg ccaaaaggag aacaagcttt tcagctttat
    61621 tcactgggaa caccaaatgg tgtgaaggtt actatcttat tggaagaatt actagaagct
    61681 ggttttaagg aagcggctta cgacttgtat aagattgcta tcatggatgg ggatcaattc
    61741 ggctcagact ttgtgaagct caatccaaat tccaagattc cagccttatt ggaccagtca
    61801 ggtactgaaa gcgtaagagt ctttgagtct gctcatattc ttctttacct tgctgagaaa
    61861 tttggagcct ttttaccaag taatcctgtg gaaaaggtag aagttttgaa ttggctattc
    61921 tggcaagcag gtgcagcacc ttttctaggt gggggatttg gacatttctt caattatgct
    61981 cctgaaaaat tggaatatcc tattaaccgt tttacgatgg aagtgaaacg ccagttggat
    62041 ttattggata aggaattggc tcagaaacct tatattgcag gcaatgacta tacgattgca
    62101 gatattgcta tctggtcttg gtatggacag ttagttcaag gaaatcttta ccaaggttct
    62161 gcaaaattct tggatgcctc aagttatcaa aatctagtaa aatgggcaga aaaaattgcc
    62221 aatcgtccag ctgttaagcg tggattggaa gtaacttata cagaaattaa atagcaaaaa
    62281 agtcatcttc ggatggcttt ttgctacagt tgagggaaag ggtttgcagt tatcggcttt
    62341 tgtgctataa ttgctataat atagtaaaaa gcaagaggag tgtgaggaag tggaaaagaa
    62401 aattgtgaag gatatcttat ttttatctca agtgtctcag ccggcaagtc aggaggacct
    62461 ttatcttgcc agagatttgc aggatacact cttagcaaat cgtgatacct gtgttggtct
    62521 agctgccaat atgattgggg tgcagaagcg cgtgattatc tttaatcttg gcttggttcc
    62581 cgtggtcatg tttaacccag tgcttctgtc ctttgaagga tcttatgagg cagaagaagg
    62641 ctgtttgtcc ttggtaggtg tgagatcaac taagcgttat gaaaccataa ggcttgccta
    62701 tcgtgacagc aagtggcagg aacagaccat taccttgaca ggcttcccag ctcagatttg
    62761 ccagcatgag ctggatcact tggaaggacg aatcatttag gaggaaagca aatgaaacga
    62821 atagtctttg aacttatttt tatcgcaacg acctggtata tctttttacc gccccttaac
    62881 ctgaccagct gggaatttct cttcttcctc tgtgggcatt tgttagttgt ggcaatctta
    62941 tttggctttg gcaaggggat aaaccttgtc aaaacggttc atgtgcgcca cggtaaggcg
    63001 gaagctgcct taaatcttga gggtttcaaa atcaatcggt tagggaaaat tctgttagct
    63061 tcgattggag gaattcttct cttggcagct ttggtttcct tggtaacttc cagcatgttt
    63121 caggctaaaa attatgccaa tgtagtcacg gttacggaaa aagactttac tgaatttcct
    63181 aggagtgaca ccagtaaggt tcctatccta gatagaagta ctgctgaaaa aattggagac
    63241 cgctacttgg gttccctaac cgataaggtg tcgcaatacg tagcggcaga tacctatacc
    63301 caattgacaa ttgatgggaa accttatcgg gtcacaccac tagaatatgc agaccctatc
    63361 aaatggttta acaatcaagc caagggaatc ggtgagtata tcaaggtgga catggtaact
    63421 ggaaatgcgg atttggtgga cttgaagaca ccaatcaagt attcagactc ggagtatttt
    63481 aaccgtgatg tcaaacgtca cctgcgcttg aagtacccga ccaaaatctt taaaactcca
    63541 tcttttgagg tggacgatga gggcaatcct ttctatgtag caacggttta ccaaaagcaa
    63601 tttggacttg ctgttcctcg tcctgcttca gtcattatct tggatgctac aaatggagaa
    63661 accaaggaat acagcttatc agatgttcca gaatgggtgg acaggatcta tccagcagag
    63721 gaaaccattg agcaaatcaa ctacaacggc aagtacaagg acggtttctt gaatgccatg
    63781 atttccaaga aaaacgtgac ccagactacc aagggctata attacttgtc tatcggtaat
    63841 gacatctatc tctacacagg tgtgacgtcg gctaatgcgg atgagagtaa tcttggtttc
    63901 atccttgaaa atatgcgaac aggagaaatc actaagtata gcttggcttc tgcgacagaa
    63961 gaatcagccc gtgaatcagc agaaggtgct gttcaggaga aatcctacaa agcaaccttc
    64021 ccaatcctca tcaacctcaa tgacaagcct ctctacatca tgggcttgaa ggacaatgct
    64081 ggcttggtca aagagtacgc cctggtagac gcagtcgagt accaaaatgt tatcgttgct
    64141 actacagtgg aagagatgct cagcaagtat gccaataaaa acgaccttga aattgacaat
    64201 gcaacgacag aaagcatcaa tggagtagta gcagacctca aatcagctgt tatcaaggga
    64261 gacactgtct acttctttaa agttgatggc aagatataca aggtcaaggc ttcagtatcc
    64321 gatgaccttc cttaccttga aaatggtaaa accttcgaag gtcaagtagg aaaagacaat
    64381 tatctcaaga cctttaagct acggtaaaaa taggtttttt tcagaaagta tatgttataa
    64441 taaggtaaat taagcctaat ggaggacaaa gaaatgggtt tttatttgat ggttgcttca
    64501 atgctactcg gactgctcgc tttgaagata ggtttttctc agttcaagga gaaaaaagat
    64561 aaattcttat ctatcttaac aagtttagct ggcacagccc ttgttctcgt ggctgtctgg
    64621 ttaggatggc ccaaataaat agaaaaacct cggtcaaacc gaggtttttc aaatgaattt
    64681 cttggttgtg gctaaaaaat atgctacact atcaatatga aaattttaat cccaacagca
    64741 aaagaaatga acacagactt gccaagtatc gaggcaattt ctttaaaacc agaaagtcag
    64801 gccgtgcttg atgccttggc tctctattct gccagtcaat tggagagttt ctacaaggta
    64861 tcagctgaga aagcggcgga agaatttcaa aatatccaag ctttgaaaag gcaaactact
    64921 caacactatc cagccttgaa actttttgat gggcttatgt accgcaacat taagagagat
    64981 aagctgaccg aggcggaaca agattatctt gaaaatcatg tcttcattac ctcggctttg
    65041 tacggtgttg ttccagcctt gtcacccatg gctcctcacc gtttggattt tttgatgaaa
    65101 ttaaaagttg ctggtaagac tttgaagagc cattggaagg cagtctatga tgaagctctg
    65161 aagaaggaag aagtgatttt ctctctcttg tcatcagagt ttgagactgt attttctaag
    65221 gaaatcagag caaagatggt gaccttcaaa ttcatggagg atagaggcgg tcagctgaag
    65281 attcactcaa ctatctccaa gaaagcgcgc ggggcctttc taacagcttt aatagaaaat
    65341 caagtacaaa ctgtggggga agcacgtcgc ttgaactttg ctggatttgt ttaccgagaa
    65401 gatttgtcac aaccacaggg attggttttt gtaaaggaag tatagaaatc agatattttg
    65461 tatttggcaa tatgtatcat cagctatttt agtttataaa tgagaaaaaa gcgaacaagc
    65521 tagtcttctg agcgtcagaa aagtagtctt gttcgctttt attatgttat actcttcgaa
    65581 aatctcttca agccatgtca gtgtcgcctt accgtatata tgttactgac ttcgtcagtt
    65641 ctatctacaa cctcaaagca gtgctttgag tagcttgcgg ctagcttcct agtttgcttt
    65701 ttgattttta ttgagtgtta gttacttgat agcttcgacc aagtcttgag cttgtttttc
    65761 aagtgagttt aggactgttt cttcaagaac caattttccg tctgcccagg cagagtcatt
    65821 aacacgtgca gcagtgaaat caccaacgcc ttgtgtacgg ataaatggca agaggtcttt
    65881 gtagatagcg aaaagttgat cgtgccctgc attggctaca gatgatactg tgacaaactt
    65941 gtcttgaagg gcagaaacgc cacgtgtatc agacaagtca agggcacgag atagccagtc
    66001 aagcaagttt ttcactgtac cagggataga gaagttgtag actggagaga aaatccagat
    66061 agcatccgca acgagaactg cttcacgagc agcagctaca gctggatgtg ttggaacttc
    66121 caaatcttgg ctgaagagag gaagggctga ataatcaagg tagctaactt ccgctttacc
    66181 agcaagtgct ttctcagctt cgagcgccat ttggtggttg aaagaacctt gacgtagtga
    66241 tccgacgata aataatactt ttttagacat gatgtgtctc ctttttctta aaatttcgag
    66301 aactctctcg ttgttataaa atatattaca acaaaacaaa agaacttgca agaaatttgc
    66361 tcagagttta tttgaaaatt gtaaaatttc ggaaactcta gtcatttgtg actgaaaaag
    66421 taagaactgt ttcactttca aaatcggttt tgtttgaagg gagaaataga attggttgct
    66481 caaagcacag ctttgaggtt gcagataaag ctgacatggt ttgaagagat tttcgaagag
    66541 tattcttata ttcacttgta ataaagctta atagatggta aaatagacga gtgaaaaaaa
    66601 gacaaaacaa agcaaaaaat aatctactgt ggcagtatgg tctagggatg acgattttgt
    66661 ttgtggttat cagtgcttcc tttctgtata tggtttctct tagcatgaaa ccctatcaaa
    66721 cagctaaaag tgaaggagaa aaattagctc agcagtatgc aggattagag caggctgatc
    66781 aggttgattt atacaatggc ttggaatctt attacagcgt tcttggtcgt aataaacagc
    66841 aagaagcgct tgctgtcctg attggtaaag atgaccataa gatttacgtt tatcagctaa
    66901 atcagggtat ttcacaagaa aaagcagaaa cggtttctaa ggaaaaggga gctggcgaga
    66961 ttgacaagat aacctttggt cgttatcaag acaagccaat ctgggaagtt aagtcaggat
    67021 ctgattttta tctagtagat tttgaaacag gagcattggt caataaggag ggcctatgaa
    67081 actatccaac cgtgttttag aaatggaaga aagtgtgact ttggctgctg gagcccgtgc
    67141 caaagcactg aaggctgagg gtagagatat tttgtctcta accttgggtg agccagattt
    67201 cactactccc aaaaatatcc aagatgccgc cattgcatcg attcgagatg ggcgtgcttc
    67261 tttttataca gtaacctcag gtctgccaga gcttaaggcg gtggtcaata gctactttga
    67321 gcgcttttac ggctattctg tagcgtcaaa tcaagtgaca gtcgctgcgg gagccaaata
    67381 ttctctctat accttcttta tggctgtggt caatccaggt gatgaagtca tcatcccaac
    67441 cccatactgg gttagctatg gagatcaggt caagatggca gaaggcgttc ccgtctttgt
    67501 ttctgctaag gaagacaatc actttaaggt gaccgtagag cagttagaag cagctcgcac
    67561 tgacaagacc aaggttttgg tgctgaattc gccatctaat cccacaggta tgatttacac
    67621 ccgtgaggaa ctcttggcaa ttggaaactg ggctgtagaa aatgatattc tcatcctagc
    67681 agatgatatc tatggccgct tggtttataa tggtcatgag ttcacaccga tttctagcct
    67741 atcggaagcg attcgcaagc aaacagtggt catcaatggt gtgtctaaaa cctatgccat
    67801 gactggttgg cggattggtt atgccgttgg agaagcagac attatcgctg ccatgtccaa
    67861 gattgcaggt caaacaactt cgaatccgtc agcagtagcc caatatgcag cagttgaggc
    67921 tctatcaggt gagcaagata ctgtagaaag catgcgtcag gcctttgagg aacgtcttaa
    67981 taccatctat cccctccttg cagaggtgcc aggatttgaa gtggtcaaac cacaaggggc
    68041 cttctatctc ttcccaaatg tcaaaaaggc catggagatg aaaggctaca cggatgtgac
    68101 agactttaca actgctatct tagaagaagc cgaagtggcc ttggtaacag gagctggatt
    68161 tggagcacca gaaaatgtcc gcctcagcta tgcgacagac ctagacacgc ttaaagaagc
    68221 agtcgaacgc ttgaaagcat ttatgggtag tgagaatgat tgatcatttt gagattaagg
    68281 taaaggattt acaaatttca gaaggatttt ataggagttt tctcgctcct ttggactata
    68341 aattggcttt taagactagt tctctaatta gttttctatc cccgaacagc cctcatcctg
    68401 gtggtgattt ttggctgact cagggaacac aagatcctgt tcattttgct tttttagcag
    68461 aaaataagga agaagttcag gcttgttatg aggctggctt agaggcaggt gggcgagaca
    68521 atggggttcc tggttatcga agtgagcatc cgatttatta tgctgctttt atgattgacc
    68581 tggatgggaa caatatagag gtggtttgcc ataaagaata aaaaagaaaa ggaaaaataa
    68641 tgacaaaacg tgtaacgatt attgatgtaa aagactatgt tggtcaggaa gtgacgattg
    68701 gcgcttgggt tgccaacaaa tcaggaaaag ggaaaatcgc tttcttacaa ttgcgtgatg
    68761 gaacagcctt ctttcaaggt gtggctttta aaccaaactt tgtcgaaaaa tttggtgaag
    68821 aagtgggact tgagaagttt gatgttatca aacgcttgag ccaagaaacg tctgtttatg
    68881 tgacaggtat tgtcaaagag gacgaacgtt ctaaatttgg ctatgagttg gacatcacag
    68941 acatcgaagt gatcggtgaa tctcaagact acccaatcac accaaaagaa cacggaacag
    69001 actttttgat ggataaccgt cacttgtggc tacgctctcg taagcaagta gctgtgttgc
    69061 aaatccgtaa cgctattatc tatgcaactt atgagttctt tgacaagaac ggttttatga
    69121 agtttgacag cccaattctt tcaggaaatg cggcagaaga ttctacagaa ctctttgaaa
    69181 ctgactactt cggaacgcca gcctacttga gccaatcagg tcagctttac ctagaagcag
    69241 gggctatggc tcttggtcgt gtctttgact ttggtccagt tttccgtgct gaaaaatcaa
    69301 aaacacgccg tcacttgact gagttctgga tgatggatgc tgagtactca tacttgacac
    69361 atgatgagtc gcttgacttg caagaagctt atgtgaaagc tcttctacaa ggtgttcttg
    69421 accgcgcgcc tcaagccttg gaaaccttgg aacgtgatac agaactcttg aaacgctaca
    69481 ttgcagagcc attcaaacgt atcacttacg atcaagccat tgacctcttg caagagcatg
    69541 aaaatgatga agatgctgac tacgagcatc ttgagcatgg tgatgacttt gggtcaccac
    69601 acgaaacttg gatttcaaac cactttggtg tgccaacatt tgtcaagaac tatccagcag
    69661 ccatcaaggc cttctacatg aaaccagttc ctggaaatcc agagcgcgtg ctttgtgcag
    69721 acttgcttgc tccagaaggc tatggagaaa ttatcggtgg gtctatgcgt gaggaagatt
    69781 acgatgccct tgtcgctaag atggatgaac ttggcatgga tcgtacagaa tatgaattct
    69841 accttgacct tcgtaaatac ggtacagttc cacacggagg atttggtatc ggtatcgaac
    69901 gtatggtaac cttcgcagca ggaacaaaac atatccgtga agctattcca ttcccacgta
    69961 tgttgcaccg tatcaaacca taagaacagg aaaacgccca tgtggcgttt tttcgaattc
    70021 tagtgttttt acttgcgtaa aaaaattttt tctagtataa tagtttattg tgagcgaacc
    70081 tcacttaccc cttgcaaagt cttggggtca ttagaccaaa aggaggaaca tatcaatggc
    70141 taaatacgaa attctttata tcattcgtcc aaacattgaa gaagaagcta aaaacgcttt
    70201 ggtagcacgt tttgactcta ttttgactga caacggtgca actgttgttg aatcaaaaac
    70261 ttgggaaaaa cgtcgtcttg catacgaaat ccaagatttc cgtgaaggac tttaccacat
    70321 cgttaacgtt gaagcaaatg acgatgcagc tcttaaagag tttgaccgtc tttcaaaaat
    70381 caacgctgac attcttcgtc acatgatcgt caaaattgac gcgtaagaag gtaaactatg
    70441 attaacaatg ttgtacttgt agggcgtatg acacgtgacg ctgagttgcg ttatacccca
    70501 tcaaatgtag cagttgcgac ttttactctt gcagtaaacc gtacatttaa gagtcaaaat
    70561 ggtgaacgtg aggctgattt tataaatgtc gttatgtggc gccaacaggc tgaaaatctt
    70621 gctaactggg ctaaaaaagg ctcacttatc ggggtgacag gtcgtatcca gactcgtagt
    70681 tacgataacc agcaaggaca acgtgtctac gtgacagagg tcgtggctga gaatttccaa
    70741 atgttggaaa gccgtagtgt gcgtgagggt cacacaggtg gagcttactc tgcaccaact
    70801 gcaaactatt cagcacctac aaattcagta ccagactttt cacgtaatga aaatccattt
    70861 ggagcaacaa acccattgga tatttcagat gatgatttac cattctaatg gacaactaaa
    70921 cttataaagg agaaaaaaca tggctcaaca acgtcgtggc ggattcaaac gccgtaaaaa
    70981 agttgattac atcgcagcaa acaaaattga atatgttgat tacaaagata ctgagcttct
    71041 tagccgtttc gtttcagaac gtgggaaaat ccttcctcgt cgtgtaacag gaacttcagc
    71101 taaaaaccaa cgtaaagtaa caacagctat caaacgcgct cgcgtaatgg ctttgatgcc
    71161 tttcgtaaac gaagattaaa gaaaagaccc ggttgggtct ctttttcatg agcttgaaaa
    71221 caagaaagcg aattaagacc ccaatgggtc ttttttcaca aactttgaaa tgagagagcg
    71281 agttaggctc agtggctccc tttttacgag tttgaaaaca agagaacaca ttaaaagcac
    71341 gatggagctt tttcataaat atgtcttttt tctcatccaa gaaattaaaa taaaaatgat
    71401 aaactttttg aaaatagggg atttgcctac tttatgatat aatggaaaga gttagattga
    71461 aagaggtagt gagatggacg cgaaattaag atacaaggca aagaagatca agattgtctt
    71521 ttttgatatt gatgatacat tgcggaattc aaagacaggg tttattccaa ctacaattcc
    71581 cactgttttt aaacagttgc gtgaaaaagg aattttaaca ggaatcgcct ctggacgtgg
    71641 catttttggt gttgttccag agattcgtga tctcaagcct gacttttttg taactttgaa
    71701 tggggcttat atcgaagata aaaaaggtca ggtcatttat cagcatcaga ttgaaaagtc
    71761 agatgttgag gagtatatct cttgggctaa gcaagaagga attgagtatg gcttggttgg
    71821 gagtcatgat gccaagttgt cgattcgcac cgatatgatg agtgaagcta tcaatccaat
    71881 ttatcccgac ttagatgtag atcccgattt ccatgaaaaa gaagatatct atcagatgtg
    71941 gacttttgaa gataagggag atgacttgca cttgcctgac agtctctcag acaaacttcg
    72001 catggttcgt tggcatcaac attcgtctga tattgtgccg atttcaggct ccaaagcgac
    72061 gggggtggaa aaggttgtgg aacaccttgg cttgaaacca gagaaggtca tggtttttgg
    72121 agatggtctc aacgacttgg aactctttga ttatgctgga atcagcgttg ccatgggaat
    72181 ttctcatgat aaaatcaaag aaaaagcaga ttatattaca aaaacattag aagaagatgg
    72241 catttttgat gccttagaag tatttggtat ggtagaaaaa gaattgcatt ttccacaagt
    72301 agacattgaa acagtagaag gtcctcttgc gactattaag accaatcacg gagacttacg
    72361 tatcaagctt ttccctgaac atgctcctaa aacagtggct aactttgtat ctctttcaaa
    72421 agatggctac tatgatggtg tcattttcca ccgtattatc aaggacttta tgatccaagg
    72481 tggagaccca actggaactg gtatgggtgg cgagtcaatc tacggcgaat cttttgagga
    72541 tgaattctca gaagagcttt acaatatccg tggtgctctt tccatggcaa atgctggtcc
    72601 aaataccaac ggcagccagt tctttatcgt gcaaaaccaa cacctacctt attctaagaa
    72661 agaaattact cgtggtggtt ggccagaacc gattgcagaa atctatgcca atcaaggtgg
    72721 gacacctcac ctagaccgcc gtcacacggt ttttggtcag ttagctgatg aagcatctta
    72781 cgctgtcttg gatgccattg ctgctgttga gacaggagct atggacaagc cagttgaaga
    72841 tgttgtaatt gaaactattg aaatcgagga ctaagatgaa aatcggtgat aagctaaagg
    72901 ggcgtattac agggattcag ccctacggtg cctttgttga gttagagacg ggtgatacgg
    72961 ggctgattca catttcagag attcggacag gatttattga aaatattcat gaaaccttga
    73021 aagtcgatga agaggttcaa gttcaggtag tggatttaga tgaatttacg gggaaagcca
    73081 gtctttctat ccgcactttg gaggaaaaaa agtaccagtt tcctagacgg agacgctttt
    73141 caagcgaccg ctttaactac ggttttgctc cctttcgacg aatgctacca atctggactg
    73201 gagaagccct gcaccattta aaaaagaaga agtagtttag agttttatat tttttgtaat
    73261 gttaatatga atttgctata ataggaccat ggaagaagaa caattattaa aatcaggaga
    73321 gcgcattaac cagctctttt cgacagatat caaaatcatt caaaatagag aggtttttag
    73381 ctattcggtg gatagtgttc tcttatcacg atttccacgt tttcctaaga aggggttgat
    73441 tgtggatttc tgtgctggga atggagcagt ggggcttttt gctagcactc gtactcaagc
    73501 acagatattg tctgttgaga ttcaggagcg tttggcggat atggctgaac gctctgtccg
    73561 tttgaatgga ttagaggagc aaatgcaggt catctgcgat gatttgaaaa atatgcctgc
    73621 tcacattcag gggagtaagg tggatatgat tttgtgtaat ccaccctatt tcaaggtgga
    73681 tccttattct aatctgaacg agagtgaaca ttatctcttg gctcgacacg aaatcacgac
    73741 taatttggaa gaaatctgtc gtagtgccca gagtattctc aagtctaatg ggcgtttggc
    73801 catggttcat cgtcctgatc gacttctgga tattttggat acgttaaaac gacataatct
    73861 agcccctaag cgcctgcagt ttgtttatcc aaaaagagaa aaggaagcca atatgctttt
    73921 gattgaggcg atcaaggatg gctcaacaag tggctttaag gtcttacctc ctttgattgt
    73981 ccacaatgat gatggctctt atacgcccga aatcgaagag atttattatg gatcataagg
    74041 cttatatgta cgttctggag tgtcgtgatg gatcctacta tataggctat acgactgata
    74101 tgagaagacg cctcgctatc cacaatagtg ggaagggagc caaatataca cgagcacgct
    74161 tgccagtcaa acttatctat gctcaaggtt ttgccagtaa ggaagaagcc atgtcggctg
    74221 aagctcttct caagcgtaag aagaggccac agaaggaaga atttttatct gaaaatcaag
    74281 atagaaattt actcagttat tttgaagaat cgtggggagt cctttgactc ctcttacctt
    74341 tgtcaaaaag cgaaaaaaat gctacaataa agaaaataaa caaaatgagg tattatcatg
    74401 tccaagattc tagtatttgg tcaccaaaat ccagactcag atgccatcgg gtcatctgta
    74461 gcttttgcct accttgcaaa agaagcttac ggtttggata cggaagctgt tgcccttgga
    74521 actccaaatg aagaaacagc ctttgtcttg aactattttg gtgtggaagc accacgtatt
    74581 atcacttctg ccaaagcaga gggggcagag caagttatct tgactgacca caatgaattc
    74641 caacaatctg tatcagatat cgctgaagta gaagtttatg gtgttgtaga ccaccaccgt
    74701 gtggctaact ttgaaactgc aagcccactt tacatgcgtt tggagccagt tggatcagcg
    74761 tcttcaatcg tttaccgtat gttcaaagaa catggtgtag ctgtgcctaa agagattgca
    74821 ggtttgatgc tttcaggttt gatttcagat acccttcttt tgaaatcacc aacaacacac
    74881 ccaacagata aaatcattgc tcctgaattg gctgaattgg ctggtgtgaa cttggaagaa
    74941 tatggtttag caatgttgaa agctggtacc aacttggcta gcaaatctgc tgaagaattg
    75001 attgacatcg atgctaagac ttttgaactc aacggaaata atgtccgtgt tgcccaagtg
    75061 aacacagttg acatcgctga agttttggaa cgccaagcag aaattgaagc tgcaatgcaa
    75121 gctgccaacg aatcaaacgg ctactctgac tttgtcttga tgattacaga tatcgtcaac
    75181 tcaaactcag aaatcttggc tcttggtgcc aatatggaca aggtcgaagc ggctttcaac
    75241 ttcaaacttg aaaaccatca tgccttcctt gctggtgccg tttcacgtaa gaaacaagtg
    75301 gtacctcaat tgactgaaag ctttaatgcg taagattttg ggtgtcagct caaaatcgga
    75361 aagtctagtt tgccttatat cgaaaggagt ttcggctcct tttttctagg agtgaagtat
    75421 gttagaaaat ggcgatttga tttttgtgag agatgggtca gacatgggac aggccatcca
    75481 gacttccaca ggtaactata gccatgttgc catttatttg gatgggatga tttatcatgc
    75541 tagtggacag gctggtgttg tctgtcaaga accggcagac ttctttgagt ccaatcattt
    75601 atacgacctc tatgtttacc cagaaatgga tatccagtcg gtgaaggaaa gagcttgcaa
    75661 acatcttgga gcaccctaca atgcttcttt ctatccagat gcagctggtt tctactgctc
    75721 ccagtatata gcagaaatcc tacctatttt tgaaactatt cctatgaaat ttggagatgg
    75781 ggagcaggag attagtgatt tttggaggga gtattacata gaactaggtc tgcctgttcc
    75841 tctgaaccaa gctggtacca atcctagtca gttggcagca tcgcctctgt tacaatgtaa
    75901 agaaagggat cttcatgatt cagattttta atccatctcg tttgacgaga cagccatttt
    75961 tggagaattg atccgctatc tggaccagta tgaggatgtg attctacggg aaattaaggc
    76021 tcaatttcca gatgttgcag ttgataaact catggaagag tatataaagg caggcttgat
    76081 tctacgtgaa aataagcgct attacctcaa ttttcctacg cttgaatcac ttgatagtct
    76141 tgaactggat caagagattt ttgtcagaga agctagtccg gtctatcaag ccttgttgga
    76201 gcagagtttt gagacggaat tgcgcaatca aatcaatgca gctattttag ttgaaaagac
    76261 ggactttgcg cgcattaaaa tgaccctgtc caattatttt tacaaggtca aacagcagta
    76321 tcctttgaca gaaaaacagc aggagctcta tgacatttta ggagatgtta atcctgagta
    76381 tgccctcaag tatatgacgg cttttttgtt gaaatttctc aaaaaagacc agcttatgca
    76441 gaaatgccgt gatatctttg tggacagttt ggttgtctta ggctatattg tgcaaaatga
    76501 agatagaaag tatgagttgg ctatcgattt tgataaggag agattaactt tctacttagc
    76561 gtgatttctt gtttctgagc acattgtttg actttcctta gtattcggta taaactatat
    76621 gtaaccggta acacatatcg gaataaacta aaggagacaa tcatatgtca cttgaaaaca
    76681 aattggaaca agcaacaggc gctgtcaaag aaggttttgg taaagttact ggagacagca
    76741 agacagaact tgaaggagct gttgaaaaaa cagttgctaa ggcaaaagac gttgtagaag
    76801 acgcaaaagg tgctgtagaa ggtgccgttg aaggtttgaa aaacgttttt actaaataat
    76861 aggaaaaaat caagggtttc attttccctt gattttttct attcttataa ataattttct
    76921 gcgacggctg tatctcctgg gtaggattct ttcttgccct ggatgatttg gtaacaatcg
    76981 actcccttac ccgcaataat aactgcatct aattcgtgat ttgtgatagc cattgccgcc
    77041 ttgatggctt cttggcgatc cgcaatcttt tcaacaggat gattgatgta gctactaatt
    77101 tcatctgcaa tggccattgg gtcttcatag ttagggtcat cagcagtcag aaagacttga
    77161 atctcagggt gttgattgag gaggaggcca aagtccttac gacgactttc tcccttgttt
    77221 cctgttgatc ccagaaccag agcaatcttt ccggtttgat gagtttcaac cacattgatg
    77281 agttttttca gactatcccc attgtgggca tagtcgatga agaccttggc tccatttttc
    77341 tgagtgagga cttccatacg accaggaacg cgggttgcag cgatgccttt tttgatgtcc
    77401 tcaagacttg ctccgagacg gagacaagca agtccagcag caactgcatt ttcttggttg
    77461 aagttgccaa tgagttgaat atcataatct ccagcgagtt tacccgtagc tgaaaagcta
    77521 aaggctttgg aattctcgat ttggttatca aattggctac catagaaatc atggtcttga
    77581 tcttcaacct gttctttcaa gactgagaag tggtccatgt cactgttaat gatgactgct
    77641 cggctctttt ccatcaagag acgcttgtgg tagaaatagt cttcaaagct agggtgttca
    77701 atcgggccga tatggtctgg gctgatattt aggaaaactc ccacatcaaa ggttagacca
    77761 tagacacgtt tgaccagata ggcttgactg gagacttcca tgatgaggtg ggtacggtca
    77821 ttttgcacag cctgattcat catgtcaaag aggtcaatac tctcaggggt tgtcaacgct
    77881 gacttaaaga aagtctcgcc atcaagagtt gtgttcatgg tcgacaacat agcaggtcta
    77941 tgcccttgag ataagatgtt ataggcgaaa taggctgctg ttgtcttacc cttagtacca
    78001 gtaaaggcaa ggagtttgag tttttcctgt ggattaccat agaactccat ggcaatcaaa
    78061 ctcatggctt tctttatatc gttcacaatg atgacaggga taccgacttc gtagtccttt
    78121 tcagctacat accaagctaa tccttgtgtt atagcagaaa gaaggtattc ttttttaaag
    78181 gcagcgcctt ttgcgaaaaa aagagtgtct tctgttactt ttcggctgtc gtagctgatg
    78241 ctatcaaaaa taactttgct gtagttgtag tggtaatgac cttggtcaat aatttcgcga
    78301 aaaaggccat ctttctttaa aatatctaat acggtttcaa tcttaatcat actttctatt
    78361 gtaaaccgaa agtcgtaaat ttacaagtaa caaggaaaag tttataatgg aagataagga
    78421 gtttttccta gctatcaaaa ttgaatgagg aatctatgtc gcacgaaaac aatcaccagc
    78481 aggcccagat gttacggggg actgcttggc taacggctag taactttatc agtcgcctac
    78541 tcggggctgt ttacattatc ccttggtaca tctggatggg ggcttatgca gctaaggcaa
    78601 atggtctctt taccatgggt tacaatatct atgcttggtt cttgttggtt tcaacagcgg
    78661 ggattccagt tgcggtggcc aagcaagttg ccaagtataa taccatgcga gaagaagagc
    78721 atagctttgc cctgattcgg agtttcttag gctttatgac aggactaggc ctggtttttg
    78781 ctttagtctt gtatgtcttt gctccttggc tagcagactt gtctggcgtg ggcaaagact
    78841 tgatcccaat catgcaaagc ttggcttggg gagtcttgat tttcccgtct atgagtgtta
    78901 tccgaggatt tttccaaggg atgaataacc tcaaacccta tgccatgagc caaattgctg
    78961 agcaggtcat tcgtgttatc tggatgctcc tagcaacctt tatcattatg aagctcggtt
    79021 caggagatta tctagcagcc gttacccaat caacctttgc tgcctttgtc ggtatggtag
    79081 ccagttttgc agtcttgatt tatttccttg cccaagaagg ttcactcaaa agagtctttg
    79141 aaacaggaga taagattaac agtaagcgtc tcttggttga taccattaag gaagccattc
    79201 cttttatcct gacagggtct gccatccagc tcttccagat tttggatcag ctgaccttta
    79261 tcaatagtat gagctggttt accaactaca gcaatgagga cttggttgtc atgttttctt
    79321 atttctcagc caatcctaat aaaatcacga tgattttgat ttctgtaggg gtttcgattg
    79381 ggagtgttgg tttgccactt ttgacggaaa actatgtcaa gggggacttg aaagcagctt
    79441 ctcgtctcgt tcaggacagt ctcaccctac tctttatgtt cttgctacca gcaacggttg
    79501 gagtggttat ggtaggagaa cctctatata cagtcttcta tggtaagcca gatagtttgg
    79561 ctctgggctt atttgtcttt gcagttttgc agtctattat tttaggcttg tacatggtct
    79621 tgtctccaat gcttcaggcc atgttccgca accgcaaggc cgttctctat tttatctatg
    79681 gttctattgc caagctagtc ttgcaactac ctaccatcgc cctcttccac agttatggtc
    79741 ctttgatttc aacaaccatt gctctcatca ttcctaacgt cttgatgtat cgggatattt
    79801 gtaaagtaac tggtgtcaag cgcaaggtga ttttgaagcg aactatttta atcagtttgc
    79861 tgaccctagt catgtttctg ttaataggaa ccatccagtg gctgttagga tttttcttcc
    79921 aaccaagtgg acgtttgtgg agcttctttt atgtagctct tgtcggtgcc atggggggtg
    79981 gactttatat ggttatgagt ctgcgtacct atttattaga taaggtaata ggaaaagccc
    80041 aagcagatcg cctgcgagca aaatttaagc tttcgtaagg tagcatttat aaataaaagg
    80101 aataagttga acaatctttt aggagaactt gaaacttatt ccttttttag cgtaaaaata
    80161 gctaaaatta tctttcaaaa atagaaaatg aggttttttt gattttttgg aaaaaacaat
    80221 tgactaaaca aaccaagagt tgtataataa aacaaatatt taaagcagga ggttccggaa
    80281 atgaaaaagt ctaagagcaa atatctaacc ttggcaggtc ttgtcctggg tacaggagtt
    80341 ttattgagcg cgtgtggaaa ttctagcacg gcgtcaaaaa cctacaacta tgtttattca
    80401 agtgatccat ctagcttgaa ctatctagca gaaaaccgcg cagcaacatc cgatattgtt
    80461 gcaaatttgg tagacgggtt attagaaaat gaccaatatg ggaatattat tccatcatta
    80521 gcagaggatt ggactgtttc tcaggacggt ttgacctata cctacaaact tcgtaaggat
    80581 gccaagtggt ttacttctga gggagaagaa tatgcgcctg taactgccca ggattttgtg
    80641 acaggtttgc aatatgcagc tgataaaaaa tcagaagcct tgtatctagt gcaggactct
    80701 gttgctggtt tggatgacta tatcactggt aaaacaagcg acttttcaac tgtcggtgtc
    80761 aaggcacttg atgaccaaac ggttcaatat actttggtta aaccagaact ttactggaat
    80821 tcaaaaacac ttgcaacgat actttttcct gttaatgcag atttcctgaa atcaaaaggg
    80881 gatgattttg ggaaggcgga tccatctagt attttgtaca atggaccttt cttgatgaaa
    80941 gcacttgtct caaaatctgc tattgaatat aagaaaaacc ctaattactg ggatgctaag
    81001 aatgtctttg tagacgatgt gaaattgacc tactatgatg gtagcgacca agaatcactg
    81061 gaacgtaatt ttacagctgg tgcttatact acggctcgtc tttttcctaa cagctccagc
    81121 tatgaaggga ttaaagaaaa atacaaaaac aatatcatct atagtatgca aaattcaact
    81181 tcatatttct ttaattttaa cctagatagg aagtcttaca attatacttc taaaacaagt
    81241 gacattgaaa agaaatcgac tcaggaagca gttctcaata aaaacttccg tcaggctatc
    81301 aattttgctt ttgacagaac atcttatggg gctcagtctg aagggaaaga aggtgcaaca
    81361 aagattttgc gtaacctagt ggttcctcca aactttgtca gtatcaaggg aaaagacttt
    81421 ggtgaagttg tagcctctaa gatggtcaac tatggtaagg aatggcaagg tatcaacttt
    81481 gcggatggtc aagaccctta ctacaatcct gagaaagcca aggctaagtt tgcggaagct
    81541 aagaaagaac tcgaagcaaa gggtgttcaa ttcccaatcc acttggataa gactgtggaa
    81601 gtaacagata aagtaggcat acaaggagtt agttctatca aacaatcaat tgaatctgtt
    81661 ttaggttctg ataatgtagt gattgacatt cagcaattaa catcagatga gtttgacagt
    81721 tcaggctact ttgctcaaac agctgctcag aaagactatg atttatatca tggcggttgg
    81781 ggacctgatt atcaagaccc gtcaacctat ctcgatattt ttaatactaa tagtggagga
    81841 gttctacaaa atcttggact agagcctgga gaagccaatg acaaggctaa ggcagttgga
    81901 ctggatgtct atactcaaat gttggaagaa gctaataaag agcaagatcc agccaaacgt
    81961 tatgagaaat atgctgatat tcaagcttgg ttgattgata gttctttagt tcttccaagt
    82021 gtttcgcgtg ggggaacacc atcattgaga agaaccgtac catttgctgc tgcctatggt
    82081 ttaaccggta caaaaggggt tgaatcatat aaatacctca aagtacaaga taagattgtc
    82141 acaacagacg aatatgcaaa agccagagaa aaatggttga aagaaaaaga agaatccaat
    82201 aaaaaagccc aagaagaatt ggcaaaacat gtcaaataaa atctaattgt agataagttt
    82261 gtgtaagaag tctttgtgct taaaaacgca taatatcagg tatataaaat cctagatgtt
    82321 atgcgttttg ttataggaag atttattaga ttttatcctc aaattgagtt attctcgact
    82381 ttatccgttg aaatattata aggagtattt atgaaattaa aattattaag agtagatact
    82441 aaggtgatta tggggagttt cttacttgtt ctgtctagtc tacttgcttt gttgcttccc
    82501 cttatcttaa agggtttaat agatgggagt tctattgaaa atataggttc caaagtattt
    82561 caatcgtttt tgatttttat tggtcaagcc ttgttttctt ctattggtta ctatctgttt
    82621 agtcaatcgg gtgaaaaaaa gatagcaaaa atcaggaaaa aagtgataga ggggttgatt
    82681 tatgcagaga aatccttctt tgataagagc caaagtgggg agttgacttc tgccattgtc
    82741 aatgacacga gtgtcattcg tgagttttta attacgactt tcccaaatat tattctgagt
    82801 ttagttatgg tacttggttc cattgtagtc ttatttagtc ttgattggaa tctttctcta
    82861 cttttattca tcactcttcc ttgtatgatg tttattatct tgcccctttc caatatcagt
    82921 gaaaagtata gtcgtcgttt acaggaggaa atcggatttt taacagggca attgactgaa
    82981 aagattcaag aacatgaatt aattaagact aaccaagcag agaaaagtgt acaggatgtt
    83041 ttggataatt gtattgaaag ggtacaaaac aattcactga aatcagatag ggttacttct
    83101 tttgagaccc cgtttgctct cttatttatc tttgcgacta tagttgtgat gctaacctat
    83161 gggggttatc gggtcagcgc aggatatata tctgtgggaa ccttggtttc gtttttgatt
    83221 tacctctttc aattacttaa tcctattagt aatatagcta attttgtaac tatttattct
    83281 aggagcaagg gatcttcagt tgcactggag aacttgcttg cagttcctaa agaaaaattt
    83341 gagtgaggaa aatcggtatc aggacaaggg ttgaatttta accatgtcta ttttggttat
    83401 gatgaaaatc gacctgtctt aaaggatatt acttgttcaa ttttcaaggg gcaaaaaatt
    83461 gcttttgttg gaccatctgg atcaggaaaa tcaacgattg tgcgtttgtt agagcggttt
    83521 tataaaccgc tttcaggata tattctaatg gagcaatcaa gtatatatga ttttaactta
    83581 aaagaatgga gaagtaaaat cgcttgggtt tcacaaaata atgcagtctt atctggcagt
    83641 attcgtgaca atctttgtct cggtttgaat cgcttagtaa ctgatgatga attgatgaaa
    83701 gtgctagact tagtatcact aggtgatgag attcgctcca tgaaagaggg actagatact
    83761 gaagttggtg aacgcggacg attcttgtca ggggggcaaa gccaaagact tcaaatagct
    83821 agaacctact taaaagatgc tgaaattctt atatttgatg aatccactgc taatcttgat
    83881 gcggattctg agtatgcgat tatcagtatc ctctattctg cattaaagga gaagacggtt
    83941 gtgattatag cgcatcgttt gtcaacggta aaagatgtgg attgtatttt cttcttagag
    84001 ggggggaaaa tcactggctc aggaactcat aaggaactac tggaaaatca tgagcgttat
    84061 gctcgttttg tgcaggagca aatgatagag tgaaggtgtc ttttgagatt caccatttta
    84121 tagtctatta aagggagcag gaaaaactcc ctttttatat agtttgaaac tataactagc
    84181 tcttgaaaag aagaaaatga gttgatgaaa ataagtggta caatagttac tatagatttg
    84241 gaggtattgt atgagcaagg aattacacat taacacaatt ttggctcagg cgggtattaa
    84301 gtcagatgaa gcgacaggtg cattggtgac accgcttcat ttttcaacga cctatcagca
    84361 tccagagttt ggtcgatcta ctgggtttga ctatacgcgc actaaaaatc caactcgtag
    84421 taaggctgag gaagtcttgg cggctattga gtcagcagac tatgccctag cgactagctc
    84481 agggatgtca gctattgtac tggcctttag cggctttcca gtaggaagta aggtcttggc
    84541 agtgcgtgat ctttacggtg gttcttttcg ctggtttaac caagtggagc aggaaggtcg
    84601 tttccatttt acctatgcca atacagaaga agagttgatt gctgagttag aaaaggatgt
    84661 ggatgttctc tatatcgaaa ccccaaccaa tcccttgatg ttggaatttg atatcgaaaa
    84721 actagcaaaa ttggctcatg ctaagggtgc caaagtggtg gtggacaata ccttctatag
    84781 ccctatctac caacgtccga ttgaagatgg agcagatatc gttctccatt cagcaaccaa
    84841 gtatctagca ggccacaatg atgtcttggc tggagtggtt gtgaccaata gtttagaact
    84901 atacgagaag cttttttaca atctcaatac aacaggggca gtcttgtctc catttgacag
    84961 ctaccagttg cttcgtggtc tcaagacctt gtctcttcgt atggagcgct caacagctaa
    85021 cgcccaagaa gtggttgcct ttttgaagga ttctccagca gttaaggaag ttctctacac
    85081 tggtcgtgga ggcatgattt cctttaaagt agccgatgaa acacgcattc ctcatatttt
    85141 gaacagtctc aaggtcttct cttttgcgga aagtttgggc ggagtggaaa gtcttattac
    85201 ttatccaacg actcaaactc atgctgatat tccagcagaa gtacgccatt cttatggttt
    85261 gacagatgac ctcttgcgtt tgtctattgg gattgaggat actagagatt tgattgcaga
    85321 tttgcgccaa gccttagaag gataagacaa agatgggaaa atatgatttt acaagcctgc
    85381 ccaaccgttt agggcaccat acctataaat ggaaagaaac agaaacggat agtgaagttc
    85441 taccagcttg gatagcggat atggactttg tggtcttgcc tgaaatccgc caagccgtgc
    85501 aaacttacgc agaccaactg gtttatggtt atacctatgc cagtgaagac ttaattaagg
    85561 aagttcaaaa gtgggaagct acacaatacg gttacaactt tgacaaagag gctcttgtct
    85621 ttatcgaggg tgtggtacca gccatctcaa cagctattca aacctttaca aaagaaggcg
    85681 aggcggtttt aattaacacg cctgtctacc caccctttgc tcgcagtgtc aagttgaata
    85741 atcgtagatt gattactaat tccttagtgg aaaaggatgg tctgtttgag attgactttg
    85801 accaacttga aaaggatttg gtggaagagg aggttaaact ctatattctt tgcaatcctc
    85861 acaatcctgg tggacgtgtt tgggaaaaag aagtgttgga gaagattggc caactctgcc
    85921 aaaaacacgg tgttttgtta gtttcggatg agattcacca agatttgacc ctctttggtc
    85981 acaaacacca gtctttcaat accatcaatc ctgccttcaa aaattttgct atcgtcttga
    86041 gcagtgccac taaaacattt aatattgctg gaacaaaaaa ttcctatgca gtcattgaaa
    86101 atcctaagtt gagactggct ttccagaaac gcctgttggc caataatcag catgaaattt
    86161 caggcttggg ttatttggcg acagaagctg cctatcgata cggtaaagat tggctagagg
    86221 aactcaagca agtctttgaa gaccacatca attatgtggt agatctattt ggaaaagaga
    86281 ctaaaatcaa ggtcatgaaa ccgcaaggta cctacttgat ttggcttgac ttttcagcct
    86341 atgacctgac tgatgaaaca ttgcaagagt tgttgagaaa tgaagccaag gttatcctca
    86401 accgtggttt ggattttgga gaggaaggaa gtctccatgc ccgcatcaat atagctatgc
    86461 ccaaatctct gttgcaggaa gtctgtcagc ggattgtggt tacttttgcc aaacgttaaa
    86521 aatccagtct tctaggagaa aagtcttcct agaaggctat tttcataggc gaaaatatgg
    86581 tataataaaa agataaggta aaggtgaaaa tatggctaaa ttgattccgg ggaaagttcg
    86641 tatcgaaggt gttgcccttt atgaaactgg taaggttgat atcatcaagg aaaagaacaa
    86701 tcggctctac gctcgcgttg cagaagaaga actgcgctat agtttagagg atgatttggt
    86761 tttttgtgcc tgtgattctt ttcaaaagag gggctactgt gtgcatttgg cagcgctaga
    86821 gcattttctg aaaaatgatg agcgtggtca ggaaatcttg tggagtctgg aagaaggtca
    86881 tgaagaaaaa gaggccgttg aaaccaaggt gaccttgggt ggcaagtttt tgaatcgaat
    86941 tttatctcca aaatcagaat gcgcctatga gttatcagct gtgggtcagg tggaagcagg
    87001 aaccaatcat atcttgtgga ctctgagaat cggccaaatc aatagccaaa aatactatgt
    87061 cattcgggat attccacttt ttttaaggat tgtcgagcag agaaagtcgt atatgattgg
    87121 caagatttat gaggagtctc tttcttggga agcctttgat gatgccagcc aagaactttt
    87181 gactttcttg cacggactaa cggaggaagg gctggttcca gacctctttt tccaaaacca
    87241 aggtcggcac ctctttttcc ctctgacctt ttttgagcag ggtgtgaatt tactgatggc
    87301 cttgccccat tttcaatttg accatcaagt ggatagctac caaaccctgc tttttcagga
    87361 tatgcatgct gatgccaatc tatttgcctt tacagtaaca gaatactcgg actattttga
    87421 aatggaaatc agtgagagtc ctagggtcaa tgtcttttat caaggagcag tacttttcca
    87481 taaaggtcag gtttattttt taacagacca gcagatgcgt cttctcaagg aaattaaagc
    87541 gttacctgtg ggtcaacaag gaaagaaata cctgcaattt gatagcagtg atcgagacaa
    87601 attggcctcc tgtctgactc tttttatcca gatgggcacc gtttcagctc cagaacgtct
    87661 acaaatcaaa acttttgcgc cctcttttta ctttgacagg gaagaagata atcggattcg
    87721 tttagaaatt cagtttgatt atggaaatag acaggtatct agccgacaag agctagaaga
    87781 attacccttt tcaagtgacg cggacttaga agaaagaatt ttccaagtct gtttggctgc
    87841 gggctttgaa gccgattttc aatcttggcg tcaggcctta aaagcggagt ctgtctatca
    87901 tttttttcat gatatcattc cagtctttga aaaactcggg catgttgacc tatcagataa
    87961 actagaagag ctttatagcc tagcgagtcc tcaggtgcag attgcctcca agggaggtct
    88021 cttggaaatc cagtttgatt ttcaaaatat tgcccaggag gaaatcgacc aagccatgca
    88081 ggccttggtt gccaatcagg atttttatat tgattcgtct aatcaagttt actttttcga
    88141 tgaagaaacc aagaaaattc gccaaaatct ccaggaactg gggcaatttg aattaaaaga
    88201 tggaaccttg caggctcgga aatccttggc ctacagttta gctcatctct ttgaagggcg
    88261 agaccgtgtt tctttttcac aagaattcca gaatctggcc caggatttga cgcatccaga
    88321 ggactttcct ttgcaagcaa ctcaggtcaa ggctgacttg cgagattatc aggaaaaggg
    88381 aattggctgg ttgcagatgc tccatcatta tggttttggt gggattttgg ctgatgatat
    88441 gggacttggg aaaacccttc agaccattgc ttttttgact agtcaagtga caaaagaaag
    88501 tcgagtcttg attctcgctc cgtcaggttt gatttacaac tgggcagatg agtttcagaa
    88561 atttgcccca cagttggatg tggttgttgt tcatggtttg aaagcaagtc gtgaggagat
    88621 tcttgccgag agccatcaaa tctatgtgac tagctatgcc accttccgtc aggacagtga
    88681 gttttatcag gggatggcct ttgacttcct tttcttagat gaggctcagg tcatgaaaaa
    88741 tgcccagacc aagattgccc agaccttgag acaatttgtg gtgccgtcgg tctttgcctt
    88801 gtcaggaact ccgattgaaa accatctggg tgagttgtgg tctattttcc aaatcgtcat
    88861 gcccggactt ttgccaagca agaaagaatt tatgaaattg ccagcagagc gagtggctca
    88921 gtttatcaag cctttcgtga tgcgacgcaa gaaagaagaa gttctgactg aattgccaga
    88981 cttgattgag gtggtttata aaaatgaact ggaagaccag caaaaggcta tttaccttgc
    89041 ccagttacaa cagatgcgag accatctggc tcaagtgtca gaacaggaat ttcagcgaag
    89101 tcgtgtggaa attttatctg gtttgatgcg cttgcgtcaa atatgtgaca ctcctgccct
    89161 gtttatggaa gattatcagg gagccagcgg caaactagat agtctccgag acctactggt
    89221 acaggtggca gacggcggac accgtgtctt gattttctct cagttcaagg gaatgttgga
    89281 aaaaattgaa caagaactgc cagacttggg cctgacttcc tttaaaatta cgggttcaac
    89341 cccagccaag gaaagacaag acatgaccaa ggcctttaat caaggagaaa gagatgcctt
    89401 tctgatttcc ctcaaggctg gtggggtcgg tctgaacctg acaggtgcag atacagtgat
    89461 cttggttgac ctttggtgga atcctgcggt ggaagcgcaa gccattggcc gtgcccatcg
    89521 gatgggtcag gaagaaacgg ttgaggtcta tcgcttggtg accaagggaa ccattgaaga
    89581 aaaaattcag gaactccaag aacaaaagaa acatctggtg tcacaagtat tggacggcac
    89641 agagtcacgt ggtagtctga ccctagcaga aattagagaa attttgggaa tttctgaagc
    89701 cagcacttga aaaatcaaga caatacgcta taatgaagtg ttgaaaggaa atagaaaatg
    89761 aaacaagaac gatttccatt ggtgtcagat gacgaggtca tgttgactga aatgccagtc
    89821 atgaatctct atgatgagtc tgatctgatc agtaatatca agggtgagta tcgagataaa
    89881 aattatttag aatgggctcc tattgctgaa gaaaaaccag tacaaccgat tgaaaagcaa
    89941 gtagggaaac ctaaaaaagc tcctttaggg gttaaaaaag aaggaaagag ctatgcggag
    90001 gtggcgcgtg aagaagcgcg tgcagacttg aaaaagaaac gctctgctaa ctatctaact
    90061 caggatttca gccttgcgag acgtcattct cagcccagtc tagttagaca gggcaatcaa
    90121 ccgacaactc ctttccaaaa ggaaaatcct ggtgaatttg tcaaatatag ccaaaaattg
    90181 acccagtctc attatatctt ggcggaagaa gttcattcta tccctaccaa gaatgaagaa
    90241 gtgtcagcac ctgctccaaa gaaaaacaat tatgattttc taaagaagag ccaaatctac
    90301 aataaaaaaa gtaaacaaac agaacaagaa cgtcgggttg cccaagagtt gaatctgacc
    90361 agaatgacag aataggggag aaaacatgtc aaagacatat cattttatcg gaattaaggg
    90421 atcagggatg agtgccttgg ccttgatgtt gcaccagatg gggcacaagg ttcagggatc
    90481 agatgttgaa aagtactact ttacccaacg cggtcttgag caggcaggaa ttaccattct
    90541 tccttttgat gaaaagaatc tagacggtga tatggaaatt atcgctggaa atgcctttcg
    90601 tccagataac aacgtcgaaa ttgcctatgc ggaccaaaat ggtatcagct acaaacgtta
    90661 ccatgagttt ctaggtagct ttatgcgtga ctttgttagc atgggagtag caggagcaca
    90721 tggaaaaact tcaacgacag gtatgttgtc tcatgtcttg tctcacatta cagataccag
    90781 cttcttgatt ggagatggga caggtcgtgg ttcggccaat gccaaatatt ttgtctttga
    90841 atctgacgaa tatgagcgtc acttcatgcc ttaccaccca gaatactcta ttatcaccaa
    90901 cattgacttt gaccatccag attatttcac aagtctcgag gatgttttta atgcctttaa
    90961 cgactatgcc aaacaaatca ccaagggtct ttttgtctat ggtgaagatg ctgaattgcg
    91021 taagattacg tctgatgcac caatttatta ttatggtttt gaagttgaag gcaatgactt
    91081 tgtagctagt gatcttcttc gttcaataac tggttcaacc ttcaccgttc atttccgtgg
    91141 acaaaacttg gggcaattcc acattccaac ctttggtcgt cacaatatca tgaatgcgac
    91201 agccgttatt ggtcttcttt acacagcagg atttgatttg aacttggtgc gtgagcactt
    91261 gaaaacattt gctggtgtta aacgtcgttt cactgagaaa attgtcaatg atacagtgat
    91321 tatcgatgac tttgcccacc atccaacaga aattattgcg accttggatg cggctcgtca
    91381 gaaataccca agcaaggaaa ttgtagcagt ctttcaaccg cataccttta caagaaccat
    91441 tgccttgttg gacgactttg cccatgcttt aaaccaagca gatgctgttt atctagcgca
    91501 aatttatggc tcggctcgtg aagtagatca tggtgacgtt aaggtagaag atctagccaa
    91561 caaaatcaac aaaaaacacc aagtgattac tgttgaaaat gtttctccgc tcctagacca
    91621 tgacaatgct gtttacgtct ttatgggagc aggagacatc caaacctatg aatactcatt
    91681 tgagcgtctc ttgtctaact tgacaagcaa tgttcaatag gatgttccca tggaaattcc
    91741 aattaagatc attcaggcaa gcaagtctga tttgcctgag ataggggcac ttcagacctc
    91801 gtcttttcca gctgaaaagc agcaactttc ccatatttta gaagaaagta tccgtaagtg
    91861 tgcggatacc tttcttctag ctagggatga aaatcaactt ttaggctata ttttatcaag
    91921 tccccagtca gacaatccgc aatatctaaa agtacattct ttagtcatcg agtctgacca
    91981 tcagagacag ggcttgggaa cacttcttct tgcagccttg aaagaggtgg cagttgagct
    92041 ggattacaaa gggattcgtt tggagagtcc tgatgagctg ctttcctatt ttgaaatgaa
    92101 cggttttgtt gatgaagaag caactttgct ctatgcaact agccagggct atagtatgat
    92161 ttggtttaat cccttttatc tggaggaaca atgaaaatca gacaagcaag attagaagat
    92221 ttggatcgga ttgttgaact tgaatttgaa aatttttcgg tcgaagaagc cattcctcct
    92281 tctgtctttg aagcacattt gagagaaatt cagacctctt ttctggttgc tgaaaaagaa
    92341 ggaagaatca tgggttatat cgaaggacca gttggcctgc accgccatct gcaagaccag
    92401 tcttttacag aagaaataaa agactatagt catgagcctg gtggttatat ctctgtgacc
    92461 tgtctgtcta ttgccaagga ggcacaggga ctcggactgg gtcagaaatt gctgacagcc
    92521 ttgaaagaag ttgctcttga agatgagaga gatggcatta atctaacctg tcatgactat
    92581 ctcatcgcct attatgaaaa acatggattt gtcaacgaag gccagtccca gtcaaccttt
    92641 gcaggggaaa catggtatga tatggtctgg gaaatgaaaa aataagttag gaaaagtatc
    92701 atagattgct ttttttggac ttttaagata taatattatg gattatcaac aaggaggaaa
    92761 aacttttgag tgaaaagtca agagaagaag agaaattaag ctttaaagag cagattctga
    92821 gagatttaga aaaagtaaaa ggctatgatg aagttctgaa agaagatgag gcagtagttc
    92881 gcactcctgc aaatgaacct tcagctgaag aactcatggc tgattccttg tcaacggtag
    92941 aggagattat gagaaaagct cctaccgtgc ctactcaccc aagtcaaggt gtaccagctt
    93001 ctccagcaga tgagattcaa agagaaactc ctggtgttcc aagtcatcca agtcaagatg
    93061 taccttcttc tccagcggaa gaaagtggat caagaccagg tccaggtcct gttagaccta
    93121 agaaacttga aagagaatac aatgaaaccc caacaagggt agctgtttcc tatacgacgg
    93181 cagagaaaaa agcagaacaa gcaggttcag aaacacctac gcctgctaca gaaacagtgg
    93241 atatcatcag cgatacatca cgtcgtagcc gtagagaagg agcaaaaccc gttaagccta
    93301 agaaagagaa gaagtcacat gtgaaagctt ttgtgatttc attccttgta ttccttgcct
    93361 tgctctcagc aggtggttac tttggttacc agtacgtgct agattctttg ttacctatcg
    93421 atgctaattc taagaaatat gtgacggttg gaattccaga aggttcaaac gttcaagaaa
    93481 tcggtacgac gcttgaaaaa gctggtttgg taaagcatgg tctgattttt agtttttatg
    93541 ccaagtataa aaattatacc gacttgaaag caggttacta caatttgcaa aagagtatga
    93601 gtacagaaga cttactcaaa gagttgcaaa aaggtggaac agatgaaccg caagaacctg
    93661 tacttgcgac tttgacaatt ccagaaggtt ataccttgga tcagattgct caagctgtgg
    93721 gtcaattgca aggtgacttc aaagagtctt tgacagcgga ggctttcttg gctaaagttc
    93781 aagatgagac gtttatcagt caagcagtag cgaaatatcc tactttactg gaaagtttgc
    93841 ctgtaaaaga cagcggtgcg cgttatcgtt tggaaggata ccttttccca gctacatact
    93901 ctatcaagga aagcacaact attgagagct tgattgatga gatgttagct gctatggata
    93961 agaacctatc tccttactat agtactatca aatctaaaaa tttgactgtc aatgagttgt
    94021 tgaccattgc ttccttggtc gaaaaagaag gtgccaagac agaagatcgt aagctcattg
    94081 caggtgtatt ctacaatcgt ttgaatcgtg atatgccact tcaaagtaat attgcaatct
    94141 tgtatgccca aggaaaactg gggcaaaata tcagtctagc tgaggatgtt gcgattgata
    94201 ccaacattga ttcaccttat aatgtttata aaaatgtagg tctcatgcct ggtccagtcg
    94261 atagtccaag tctggatgcg attgagtcaa gcatcaatca aactaagagc gataacctct
    94321 actttgtagc agatgtcaca gaaggcaagg tctactatgc taacaatcaa gaagaccacg
    94381 accgcaatgt cgctgaacat gtcaacagca aattaaacta aacaaactaa aattatgtga
    94441 tacttcacat aattttcttt agaaaatatt atcagaagaa agttgagaaa aatggcagaa
    94501 aaaacatatc ctatgaccct tgaggaaaag gaaaaacttg aaaaagaatt agaagaattg
    94561 aaattggttc gtcgaccaga agtggtagaa cgcattaaga ttgcccgttc atacggtgac
    94621 ctttcagaaa acagtgagta cgaagcagct aaggatgaac aagcctttgt cgaaggacaa
    94681 atctctagct tagaaacaaa aatccgctat gctgaaatcg tcaatagcga cgcagttgcc
    94741 caggacgaag tagcgattgg taaaacagtc accatccaag aaattggtga ggacgaagaa
    94801 gaagtttata ttatcgtagg ttcagctggt gcggatgcct ttgcaggtaa ggtttcaaat
    94861 gaaagcccaa ttgggcaggc cttgattggc aagaaaacag gtgatacagc aaccattgaa
    94921 acgcctgttg gtagctatga tgtaaaaatc ttgaaggttg aaaaaacagc ctaaaaacag
    94981 aaaaaggagt ggggaggcga tgtgcttcac tcactccttt ttccattttg ctactcttcg
    95041 aaaatctctt caaaccacgt cagcgtcgcc ttgccgtatg tatggttact gacttcgtca
    95101 gtttcctagt ttgctctttg attttcattg agtattagat gtataatgca ttgaagttaa
    95161 aatagtacac tttgatttct aagacattgt tagaaattag attaaattcc ttaatcgatt
    95221 tgcgcatgtt ttatttcatt tcattatacc ttagattgga aaataaggaa tcacataaat
    95281 cgcaagaaat agggaatctg attcgtgttt ataaccgttc aaaaagagaa gaggctgaaa
    95341 gtgagccact taatctttat gtcgaagatg aaaagggcaa tctccttgcg ggtttgatag
    95401 cagagacttt tggaaattgg ctagaaatcg agtatttgtt tgtaaaagag gaactgcgag
    95461 ggcaaggaat cggttcaaaa ctattgcaac aggcagaaag tgaagctaag aatcgaaatt
    95521 gttgttttgc ctttgtcaat acttaccagt tccaggcact ggacttttat cagaaacatg
    95581 gctacaagga agttttttct ttgcaagact atctctacat taggcaaaga tattattacc
    95641 aaaagaatct gtaaggcgag tatggaggtg gactgatgta tatgagtaac tatcgataaa
    95701 taccagttat aacctagaaa ttgtgtcttt ctagacgata ttgaggacaa tataatcgta
    95761 gccccaaaat taggaatcaa ggcttatcag gttaagaaaa gaagtgatgt tgttgatatt
    95821 ttaaaacaat ttatttaaac taaaaactct ctatcttttt aaattgacat taatccgaga
    95881 ttcccctctc ggattttgtg ttgctttcat taaatttaca ggtaagcctt gctagcttca
    95941 gtaaatatac acaagttttt cagaatagag tgaaatccaa aagaaaatgg aaataatgaa
    96001 agctcttgta ggcataagaa aacacctctg tgttatactt gttgttcaac cacaaacaca
    96061 agaaaggcac agagatgcaa aaccattata ctacaaaagg taaacatttg acaatcgata
    96121 gccgtcgctt aatcgaacga tggaaaaaag aaggaaaatc aaatagagaa attgcctctc
    96181 tgcttggaaa agttcctcaa actatccaca ctgaaatcaa gcgtgggaca gtccgacaat
    96241 gtcttggaaa agggcgcttc aaagaggttt attctgccga ctatgctcaa cagtcttatg
    96301 aaaacaatcg caagcgctcg gtcaggaaat taagcgtgac caaggaacta aaggaaaaga
    96361 ttctccacta tcataaccaa aaattttcgc ctgaaatgat ggtgatggct aaaggggtta
    96421 acgtgggaat ttcaaccatt tactattgga ttcatcatgg aaaattgggg ttaagcaaac
    96481 aggatctgct ttaccctaga aaaggaaaag cgcttaagaa acaggctagc atcaacttta
    96541 aacctgctgg tcaatccatc gcacagcggc ctgaagctat caatcttcgc ttggagaatg
    96601 ggcattatga gattgatacg gttctactta cgagagcgaa aaactactgc ttgcttgtct
    96661 tgacggatcg aaagagtaga catcagatca tccgattgat tccaaataaa agtgctgagg
    96721 tggtcaatca ggctctaaaa ctcatcttaa aacaacacaa gattctttcc atcacggcag
    96781 ataatggaac ggaattcaat cgcttgtttg atatattttc tgaggagcac atctattatg
    96841 cgcaccccta tgcctcttgg gaaaggggaa ctaatgagaa tcacaacagg ctcattcgta
    96901 gatagttacc taagggaacc aagaaaatga ctcccaaaga agtcgcattc atcgaaaagt
    96961 ggattaacaa ctatcctaaa aaatgcttgg actacaagtc acccagagaa gacttctgga
    97021 tggctaactt gaacttgaaa tttagcaaaa tggaaataat ttttattaaa cgcttccaat
    97081 agcggttaaa agttgacaaa tttaaatttt aggactacac taagtaagta aattttattt
    97141 taaaggagaa tttgttatga atttaacatt tttaggctta tgtattgcct gtatgggcgt
    97201 atctgtcggt gaaggtttat tgatgaatgg actgtttaaa tcagtagcac gccaaccaga
    97261 tatgctttct gagtttcgta gtttgatgtt tttaggtgtt gcctttattg aaggaacttt
    97321 ctttgtaact cttgtcttct catttattat caaataaata catggaacga gaagaaaagg
    97381 gaggatttta gatggaagaa agtattaatc caatcatctc tattggtcct gttatcttca
    97441 atctgactat gttagccatg actttgttga ttgtgggagt tatttttgtc tttatttatt
    97501 gggcaagccg caatatgacc ttgaaaccca aaggaaagca aaatatactt gagtatgtct
    97561 atgactttgt tattggattt acagaaccta acattggttc gcgctacatg aaagattact
    97621 cactcttttt cctttgttta ttccttttca tggtgattgc caataacctt ggcttaatga
    97681 caaagcttca aacgatcgat gggactaact ggtggagttc gccaaccgct aatttacagt
    97741 atgacttaac cttatctttt cttgtcattt tgttgacaca tatagaaagc gttcgtcgtc
    97801 gtggatttaa aaaaagtata aaatctttta tgagtcctgt ttttgtcata ccgatgaata
    97861 tcttggaaga atttacaaac ttcttatctt tggctttgcg gatttttggg aatatctttg
    97921 caggagaggt catgacgagt ttgttacttc ttctttccca ccaagctatt tattggtatc
    97981 cagtagcctt tggagctaat ttggcttgga ctgcattttc tgtctttatt tcctgcatcc
    98041 aagcttatgt ttttactctt ttgacatctg tgtatttagg gaataagatt aatattgaag
    98101 aggaatagaa aggagtaact gatgcacgta acagtaggtg aattaattgg taattttatt
    98161 ttaatcactg gctcttttat tcttttgcta gtcttgatta aaaaatttgc atggtctaat
    98221 attacaggca ttttcgaaga aagagctgaa aaaattgctt cagatattga tagagctgaa
    98281 gaagcccgtc aaaaagcaga agtattggct caaaaacgcg aagatgaatt ggctggtagc
    98341 cgtaaagaag ctaagacaat cattgaaaat gcaaaggaaa cagctgagca aagtaaggct
    98401 aatatcttag cagatgctaa actagaagca ggacacttaa aagaaaaagc caatcaagaa
    98461 attgctcaaa ataaagtaga agctttacag agtgttaagg gtgaggtcgc agatttgacc
    98521 atcagcttag ctggtaaaat catctcacaa aaccttgaca gtcatgccca taaagcactc
    98581 attgatcagt atatcgatca gctaggagaa gcttaatgga caagaaaaca gtaaaggtaa
    98641 ttgaaaaata cagcatgcct tttgtccaat tggtacttga aaaaggagaa gaagaccgta
    98701 tcttttcaga cttgactcaa atcaagcaag ttgttgaaaa aacaggtctg ccttcttttt
    98761 taaaacaagt ggcagtagac gagtcggata aggaaaaaac aattgctttt ttccaagatt
    98821 ctgtgtcgcc tttattacaa aactttatcc aggttctggc ctacaatcac agagcaaatc
    98881 ttttttatga tgtgcttgta gattgcttga accgacttga aaaagaaaca aatcgatttg
    98941 aagtgacgat tacgtctgct catcctctaa ctgatgaaca gaagactcgt ttgctccctt
    99001 tgattgagaa aaaaatgtct ctgaaagtaa ggagtgtaaa agaacaaatc gatgaaagtc
    99061 tcattggtgg ttttgtcatt tttgccaatc acaagacaat tgatgtgagt attaaacaac
    99121 aacttaaagt tgttaaagaa aatttgaaat agaaagtggt gttcttttgg caattaacgc
    99181 acaagaaatc agcgctttaa ttaagcaaca aattgaaaat ttcaaaccca attttgatgt
    99241 gactgaaaca ggtgttgtaa cctatatcgg ggacggtatc gcgcgtgctc atggccttga
    99301 aaatgtcatg agtggagagt tgttgaattt tgaaaacggc tcttatggta tggctcaaaa
    99361 cttggagtca acagacgttg gtattatcat cctaggtgac tttacagata tccgtgaagg
    99421 cgatacaatc cgccgtacag ggaaaatcat ggaagtccct gtaggtgaaa gtctgattgg
    99481 tcgtgttgtg gatccgcttg gtcgtccagt tgacggtctt ggagaaatcc acactgataa
    99541 aactcgtcca gtagaagcac cagctcctgg tgttatgcaa cgtaagtctg tttcagaacc
    99601 attgcaaact ggtttgaaag ctattgacgc ccttgtaccg attggtcgtg gtcaacgtga
    99661 gttgattatc ggtgaccgtc agacagggaa aacaaccatt gcgattgata caatcttgaa
    99721 ccaaaaagat caagatatga tctgtatcta cgtcgcgatt ggacaaaaag aatcaacagt
    99781 tcgtacgcaa gtagaaacac ttcgtcagta cggtgccttg gactacacaa tcgttgtgac
    99841 agcctctgct tcacaaccat ctccattgct cttcctagct ccttatactg gggttgctat
    99901 ggcggaagaa tttatgtatc aaggtaagca tgttttgatt gtatacgatg atctatcaaa
    99961 acaagcggta gcttatcgtg aactatcgct cttgcttcgt cgtcctccag gtcgtgaagc
   100021 cttcccaggg gatgttttct atctccacag ccgtttgctt gagcgctcag ctaaagtttc
   100081 tgatgaactt ggtggtggat caattacagc cctaccattt atcgagacac aagcaggaga
   100141 tatctcagcc tatatcgcaa ccaacgtgat ttctatcact gatggacaaa tcttccttgg
   100201 cgatggcctc ttcaatgcag gtattcgtcc agccatcgat gcgggttcat ctgtatctcg
   100261 tgtaggtggt tctgcacaaa tcaaagccat gaagaaggtt gctggtacac ttcgtatcga
   100321 ccttgcttca taccgtgagt tggaagcctt tactaagttt ggttctgact tggacgcagc
   100381 aacacaggct aagttgaacc gtggacgtcg taccgttgag gtcttgaaac aacctgttca
   100441 caaaccatta cctgttgaga aacaagtaac cattctttat gctttgacac atggtttctt
   100501 ggatactgtt ccagtagatg atattgttcg tttcgaggaa gagttccatg ccttctttga
   100561 tgctcaacat ccagagattt tggaaaccat tcgtgataca aaagacttgc cagaagaagc
   100621 agtcttggat gctgcgatta cagagtttct caatcaatct agcttccaat aagaatagag
   100681 gtgtcagatg gcagtgtctc taaatgatat taaaacaaaa atcgcctcaa caaaaaatac
   100741 gagtcaaatc actaatgcca tgcaaatggt atcggctgct aagttaggtc gctctgaaga
   100801 agctgctcgc aacttccaag tttacgctca gaaagtgcgt aaacttttga cagatatcct
   100861 tcatggtaat ggagctggtg cttcaactaa tccgatgttg attagccgtt ctgtgaagaa
   100921 gacaggctat atcgttatca cttcagaccg cggtttggtt ggaggttata attcctctat
   100981 tttgaaagct gttatggagt tgaaagaaga ataccaccca gacggtaaag gttttgaaat
   101041 gatctgtatc ggtgggatgg gagctgattt ctttaaggct cgcggtattc aaccacttta
   101101 tgaattacgt ggcttggcag accaacctag ctttgatcaa gttcgtaaga ttatttcaaa
   101161 aactgttgaa atgtaccaaa atgaactctt tgatgagctt tatgtttgct acaaccacca
   101221 tgtcaatacg ctaaccagtc aaatgcgtgt ggaacaaatg cttccgattg ttgacttgga
   101281 tccaaatgaa gcggatgaag agtacagctt gacttttgaa ttggaaacca gccgagaaga
   101341 aattctggag cagttgttgc ctcagtttgc agaaagtatg atttacggtg ccattatcga
   101401 tgccaagaca gctgagaatg ctgcgggtat gacagccatg caaacagcga cagataatgc
   101461 taagaaagtc atcaatgatt tgacaattca gtataaccgt gccagacagg cggcgattac
   101521 acaagaaatt acagaaatcg tagcaggtgc tagtgcctta gaataggctc tagtccagct
   101581 cgtatgaaaa tgaacttagg acctagttga gctaggaacc gacagtatct tatatagaat
   101641 aggagaagga gatgagttca ggtaaaattg ctcaggttat cggtcccgtt gtagacgttt
   101701 tgtttgcagc aggggaaaaa cttcctgaga ttaacaatgc acttgtcgtc tacaaaaatg
   101761 acgaaagaaa aacaaaaatc gtccttgaag tagccttgga gttaggagat ggtatggttc
   101821 gtactatcgc catggaatca acagatgggt tgactcgtgg aatggaagta ttggacacag
   101881 gtcgtccaat ctctgtacca gtaggtaaag aaactttggg acgtgtcttc aacgttttgg
   101941 gagataccat tgatttggaa gctcctttta cagaagacgc agagcgtcag ccaattcata
   102001 aaaaagctcc aacttttgat gagttgtcta cctcttctga aatccttgaa acagggatca
   102061 aggttattga ccttcttgcc ccttacctta aaggtggtaa agttggactt ttcggtggtg
   102121 ccggagttgg taaaaccgtc ttaatccaag aattgattca caacattgcc caagagcacg
   102181 gtggtatttc agtatttact ggtgttgggg aacgtactcg tgaggggaat gacctttact
   102241 gggaaatgaa agaatcaggc gttatcgaga aaacagccat ggtctttggt cagatgaatg
   102301 agccaccagg agcacgtatg cgtgttgccc ttactggttt gacaatcgct gaatacttcc
   102361 gtgatgtgga aggccaagac gtgcttctct ttatcgataa tatcttccgt ttcactcagg
   102421 ctggttcaga agtatctgcc cttttgggtc gtatgccatc agccgttggt taccaaccaa
   102481 cacttgctac ggaaatgggt caattgcaag aacgtatcac atcaaccaag aagggttctg
   102541 taacctctat ccaggctatc tatgtgccag cggatgacta tactgaccca gcgccagcaa
   102601 cagccttcgc tcacttggat tcaacaacaa acttggaacg taagttggta caattgggta
   102661 tctacccagc cgttgaccca cttgcttcaa gctcacgtgc cttggcacct gaaatcgttg
   102721 gagaagagca ctatgcagtt gctgctgaag taaaacgtgt ccttcaacgt taccatgaat
   102781 tgcaagatat cattgctatc cttggtatgg atgagctttc tgatgaagaa aagaccttgg
   102841 ttgctcgcgc ccgtcgtatc cagttcttct tgtcacaaaa cttcaacgtt gcggaacaat
   102901 ttactggtca gccaggttct tatgttccag ttgctgaaac tgtacgtggc tttaaggaaa
   102961 tccttgatgg taaatacgac cacttgccag aagatgcctt ccgtggtgta ggttctatcg
   103021 aagatgtgat tgcaaaagct gaaaaaatgg gattttaaga ggtgatctat ggctcagtta
   103081 actgtccaga tcgtgacacc agatggtctc gtctatgatc accatgccag ctatgtatcg
   103141 gttcgaactc tggatggtga gatggggatc ttgccacgac atgaaaatat gattgcggtt
   103201 ttagcagttg atgaagtaaa ggtaaaacgt atcgatgata aagatcacgt gaactggatt
   103261 gcagtaaacg gtggcgttat tgaaattgcc aatgatatga tcacaatcgt cgctgactct
   103321 gcagaacgtg ctcgtgatat cgatatcagt cgtgcagaac gtgccaaact tcgtgcagaa
   103381 cgtgcaattg aagaagcaca agacaaacat ttgattgacc aagaacgtcg tgctaagatt
   103441 gctttgcaac gtgctattaa ccgtattaat gtcggaaata gactataaga aaaaatgaac
   103501 ttgaaaatac
//
LOCUS       DAVKEV010000002        68964 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVKEV010000002 DAVKEV010000000
VERSION     DAVKEV010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68964
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.002"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..188
                     /locus_tag="VWZ68_000126"
     CDS             <1..188
                     /locus_tag="VWZ68_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU9371235.1"
                     /translation="MATGWVKDKGLWYYLNESGSMATGWFTVSGQWYYTYNSGDLLVN
                     TTTPDGYRVNANGEWVG"
     gene            complement(667..816)
                     /gene="rpmG"
                     /locus_tag="VWZ68_000127"
     CDS             complement(667..816)
                     /gene="rpmG"
                     /locus_tag="VWZ68_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU9371236.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(832..1014)
                     /gene="rpmF"
                     /locus_tag="VWZ68_000128"
     CDS             complement(832..1014)
                     /gene="rpmF"
                     /locus_tag="VWZ68_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEU9371237.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            complement(1166..1366)
                     /locus_tag="VWZ68_000129"
     CDS             complement(1166..1366)
                     /locus_tag="VWZ68_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU9371238.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            complement(1369..2376)
                     /locus_tag="VWZ68_000130"
     CDS             complement(1369..2376)
                     /locus_tag="VWZ68_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU9371239.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKKYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            2567..4597
                     /locus_tag="VWZ68_000131"
     CDS             2567..4597
                     /locus_tag="VWZ68_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU9371240.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            4601..4885
                     /locus_tag="VWZ68_000132"
     CDS             4601..4885
                     /locus_tag="VWZ68_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9371241.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            4898..6244
                     /locus_tag="VWZ68_000133"
     CDS             4898..6244
                     /locus_tag="VWZ68_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU9371242.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFITKPSAKEE"
     gene            6248..7105
                     /locus_tag="VWZ68_000134"
     CDS             6248..7105
                     /locus_tag="VWZ68_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU9371243.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            7102..8034
                     /locus_tag="VWZ68_000135"
     CDS             7102..8034
                     /locus_tag="VWZ68_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEU9371244.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSSLCELFSDDGMTKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            8267..9970
                     /gene="ilvD"
                     /locus_tag="VWZ68_000136"
     CDS             8267..9970
                     /gene="ilvD"
                     /locus_tag="VWZ68_000136"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEU9371245.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(10131..10211)
                     /locus_tag="VWZ68_000137"
                     /pseudo
     CDS             complement(10131..10211)
                     /locus_tag="VWZ68_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10269..10610)
                     /locus_tag="VWZ68_000138"
     CDS             complement(10269..10610)
                     /locus_tag="VWZ68_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU9371246.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            10734..11585
                     /gene="rgg"
                     /locus_tag="VWZ68_000139"
     CDS             10734..11585
                     /gene="rgg"
                     /locus_tag="VWZ68_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEU9371247.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            11778..13025
                     /locus_tag="VWZ68_000140"
     CDS             11778..13025
                     /locus_tag="VWZ68_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEU9371248.1"
                     /translation="MKLLFRNPAYRILILSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            13103..14392
                     /locus_tag="VWZ68_000141"
     CDS             13103..14392
                     /locus_tag="VWZ68_000141"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEU9371249.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKEA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVSYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFVAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            14383..14463
                     /locus_tag="VWZ68_000142"
                     /pseudo
     CDS             14383..14463
                     /locus_tag="VWZ68_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            14733..15047
                     /locus_tag="VWZ68_000143"
     CDS             14733..15047
                     /locus_tag="VWZ68_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371250.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            15057..15263
                     /locus_tag="VWZ68_000144"
     CDS             15057..15263
                     /locus_tag="VWZ68_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9371251.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            15263..15460
                     /locus_tag="VWZ68_000145"
     CDS             15263..15460
                     /locus_tag="VWZ68_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371252.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQGDQFVWLYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            15463..16197
                     /locus_tag="VWZ68_000146"
     CDS             15463..16197
                     /locus_tag="VWZ68_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEU9371253.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            16209..16850
                     /locus_tag="VWZ68_000147"
     CDS             16209..16850
                     /locus_tag="VWZ68_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9371254.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            16868..17098
                     /locus_tag="VWZ68_000148"
     CDS             16868..17098
                     /locus_tag="VWZ68_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371255.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            17450..19213
                     /gene="aspS"
                     /locus_tag="VWZ68_000149"
     CDS             17450..19213
                     /gene="aspS"
                     /locus_tag="VWZ68_000149"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEU9371256.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            19191..20132
                     /locus_tag="VWZ68_000150"
     CDS             19191..20132
                     /locus_tag="VWZ68_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU9371257.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(20342..20422)
                     /locus_tag="VWZ68_000151"
                     /pseudo
     CDS             complement(20342..20422)
                     /locus_tag="VWZ68_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(20558..21544)
                     /locus_tag="VWZ68_000152"
     CDS             complement(20558..21544)
                     /locus_tag="VWZ68_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9371258.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKVFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(21554..22354)
                     /locus_tag="VWZ68_000153"
     CDS             complement(21554..22354)
                     /locus_tag="VWZ68_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEU9371259.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PGQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(22615..23457)
                     /locus_tag="VWZ68_000154"
     CDS             complement(22615..23457)
                     /locus_tag="VWZ68_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9371260.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(23459..24751)
                     /locus_tag="VWZ68_000155"
     CDS             complement(23459..24751)
                     /locus_tag="VWZ68_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9371261.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(24862..26133)
                     /locus_tag="VWZ68_000156"
     CDS             complement(24862..26133)
                     /locus_tag="VWZ68_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9371262.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            26683..28200
                     /gene="malQ"
                     /locus_tag="VWZ68_000157"
     CDS             26683..28200
                     /gene="malQ"
                     /locus_tag="VWZ68_000157"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEU9371263.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            28226..30484
                     /gene="glgP"
                     /locus_tag="VWZ68_000158"
     CDS             28226..30484
                     /gene="glgP"
                     /locus_tag="VWZ68_000158"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEU9371264.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(31529..32101)
                     /locus_tag="VWZ68_000159"
     CDS             complement(31529..32101)
                     /locus_tag="VWZ68_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371265.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTTIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     SAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(32724..33572)
                     /locus_tag="VWZ68_000160"
     CDS             complement(32724..33572)
                     /locus_tag="VWZ68_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU9371266.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            33724..34002
                     /locus_tag="VWZ68_000161"
     CDS             33724..34002
                     /locus_tag="VWZ68_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371267.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            34004..36067
                     /locus_tag="VWZ68_000162"
     CDS             34004..36067
                     /locus_tag="VWZ68_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU9371268.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIKLMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(36145..37401)
                     /locus_tag="VWZ68_000163"
     CDS             complement(36145..37401)
                     /locus_tag="VWZ68_000163"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEU9371269.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            37543..40008
                     /locus_tag="VWZ68_000164"
     CDS             37543..40008
                     /locus_tag="VWZ68_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU9371270.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            40073..40984
                     /locus_tag="VWZ68_000165"
     CDS             40073..40984
                     /locus_tag="VWZ68_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU9371271.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            41214..41912
                     /gene="dapD"
                     /locus_tag="VWZ68_000166"
     CDS             41214..41912
                     /gene="dapD"
                     /locus_tag="VWZ68_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEU9371272.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            41980..43110
                     /locus_tag="VWZ68_000167"
     CDS             41980..43110
                     /locus_tag="VWZ68_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEU9371273.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            43122..43661
                     /locus_tag="VWZ68_000168"
     CDS             43122..43661
                     /locus_tag="VWZ68_000168"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEU9371274.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMEFVVYDPQQLVKTSFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            43645..44322
                     /locus_tag="VWZ68_000169"
     CDS             43645..44322
                     /locus_tag="VWZ68_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEU9371275.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(44394..45293)
                     /gene="galU"
                     /locus_tag="VWZ68_000170"
     CDS             complement(44394..45293)
                     /gene="galU"
                     /locus_tag="VWZ68_000170"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU9371276.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(45315..46331)
                     /locus_tag="VWZ68_000171"
     CDS             complement(45315..46331)
                     /locus_tag="VWZ68_000171"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU9371277.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            46553..46956
                     /locus_tag="VWZ68_000172"
                     /pseudo
     CDS             46553..46956
                     /locus_tag="VWZ68_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823968.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            complement(47071..47496)
                     /locus_tag="VWZ68_000173"
     CDS             complement(47071..47496)
                     /locus_tag="VWZ68_000173"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9371278.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(47564..48214)
                     /gene="phoU"
                     /locus_tag="VWZ68_000174"
     CDS             complement(47564..48214)
                     /gene="phoU"
                     /locus_tag="VWZ68_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU9371279.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(48229..48981)
                     /gene="pstB"
                     /locus_tag="VWZ68_000175"
     CDS             complement(48229..48981)
                     /gene="pstB"
                     /locus_tag="VWZ68_000175"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU9371280.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(48983..49798)
                     /gene="pstA"
                     /locus_tag="VWZ68_000176"
     CDS             complement(48983..49798)
                     /gene="pstA"
                     /locus_tag="VWZ68_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU9371281.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(49791..50654)
                     /gene="pstC"
                     /locus_tag="VWZ68_000177"
     CDS             complement(49791..50654)
                     /gene="pstC"
                     /locus_tag="VWZ68_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU9371282.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(50772..51647)
                     /locus_tag="VWZ68_000178"
     CDS             complement(50772..51647)
                     /locus_tag="VWZ68_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEU9371283.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGKYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(51814..53145)
                     /locus_tag="VWZ68_000179"
     CDS             complement(51814..53145)
                     /locus_tag="VWZ68_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEU9371284.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMVLTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(53146..53853)
                     /locus_tag="VWZ68_000180"
     CDS             complement(53146..53853)
                     /locus_tag="VWZ68_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9371285.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(53937..54239)
                     /locus_tag="VWZ68_000181"
     CDS             complement(53937..54239)
                     /locus_tag="VWZ68_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU9371286.1"
                     /translation="MTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            complement(54226..54447)
                     /locus_tag="VWZ68_000182"
     CDS             complement(54226..54447)
                     /locus_tag="VWZ68_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU9371287.1"
                     /translation="MNKSYFNPLAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINL
                     AGKGRALYTSIYFLLRRNESFTFSPIDSR"
     gene            54409..54967
                     /locus_tag="VWZ68_000183"
                     /pseudo
     CDS             54409..54967
                     /locus_tag="VWZ68_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(55282..56973)
                     /locus_tag="VWZ68_000184"
     CDS             complement(55282..56973)
                     /locus_tag="VWZ68_000184"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEU9371288.1"
                     /translation="MNTKELIASELSSIIDSLDQEAVLKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            57109..57555
                     /gene="argR"
                     /locus_tag="VWZ68_000185"
     CDS             57109..57555
                     /gene="argR"
                     /locus_tag="VWZ68_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU9371289.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            57606..60140
                     /gene="mutS"
                     /locus_tag="VWZ68_000186"
     CDS             57606..60140
                     /gene="mutS"
                     /locus_tag="VWZ68_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEU9371290.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDCEGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            60287..61981
                     /gene="patA"
                     /locus_tag="VWZ68_000187"
     CDS             60287..61981
                     /gene="patA"
                     /locus_tag="VWZ68_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEU9371291.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELFGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(62312..62581)
                     /locus_tag="VWZ68_000188"
                     /pseudo
     CDS             complement(62312..62581)
                     /locus_tag="VWZ68_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            62773..64539
                     /gene="patB"
                     /locus_tag="VWZ68_000189"
     CDS             62773..64539
                     /gene="patB"
                     /locus_tag="VWZ68_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEU9371292.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAHQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPIMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            64678..65367
                     /locus_tag="VWZ68_000190"
     CDS             64678..65367
                     /locus_tag="VWZ68_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU9371293.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            65371..65550
                     /locus_tag="VWZ68_000191"
     CDS             65371..65550
                     /locus_tag="VWZ68_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371294.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            65537..66886
                     /locus_tag="VWZ68_000192"
     CDS             65537..66886
                     /locus_tag="VWZ68_000192"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEU9371295.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAVVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            67010..68470
                     /locus_tag="VWZ68_000193"
     CDS             67010..68470
                     /locus_tag="VWZ68_000193"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEU9371296.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            68484..68918
                     /locus_tag="VWZ68_000194"
     CDS             68484..68918
                     /locus_tag="VWZ68_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU9371297.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERATLFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT        20224 a        12827 c        14915 g        20998 t
ORIGIN      
        1 caatggctac tggttgggtt aaagacaaag gcttatggta ttacttaaat gaatcaggtt
       61 caatggctac tggttggttt acagtttctg gtcaatggta ctatacctat aattcaggag
      121 atttattagt aaacacgact acacccgatg gctatcgagt caatgctaac ggtgagtggg
      181 taggataggt atccattagc taaatctaat cattctgaac taaaaaatct tcttacatat
      241 gtaggaagat tttttggatt ctcaaaacta gtttaaaaga ctacgctatt taaaccaatt
      301 ttaagaatgg atatataagg atattcagaa atctagttgg tcaacttttg tattttgaat
      361 ataccttaga tggtgacgat gtcttggtat atctggtact cacttacata ttctaactta
      421 ttttaactaa gatacaactg tagttggtga atttgctaca aatagtgtag aggcgttatt
      481 tgaaaaatat acaaaaaagg aaccccaact tacatttgag ttcctcttgc ttttaattgt
      541 ccgaatccgt attcttattt caataatgta gtcattcgaa tgatttccct tgcaatatag
      601 tgaaattaac aaaaagaaaa aacgctgatc aagcgttttt cttctgtatt gattcgtatt
      661 gaatgcttac ttcacttctg taaacacaac gtgtttgcga agttttggtg agtatttctt
      721 caattgaagg cggtctggag tgttacgttt gtttttagaa gtaaggtaca agcgttcacc
      781 agattctttg tgttcaagtg taatatttac gcgcatagta tctcccttct attattcagc
      841 tgatgcagct ttagcgattt tacgtccttt gtagtatcct ttaagtgata cacggtgaga
      901 acgtgagtaa tctccagtag tttcgtcaaa gtttacagat ggagctgtta ctttgtagtg
      961 tgtacgacgt ttgtttttct tcgcttttga agtgcgacgt gcaggtactg ccattttgat
     1021 ttctccttta ggtatttata ttcgattcaa tctactgatt ttcatcaacc atactaggat
     1081 aacacatttt ttttgtaaag taaagttact tgacaaaaaa agatgaaaaa attctcctat
     1141 ccgacacggc agacaggaga aggtgttaaa tatcaatctc aaatggttcg tcaatggttt
     1201 ctgatacgta ttttccgtct tttttccgtt gcttgacaca ctctgtgagg agatattcta
     1261 tttgcccatt gactgaacga aagtcgtctt ctgcccatga tgcgagtgca gcgtataact
     1321 ttgttgagag tcgaaggggg atctgctttt ttttagcttc agccatcttt agtaaagact
     1381 tcctgtgttg acaattggtt gtgcatcatg attgccacaa agaacgacaa ggagatttga
     1441 aaccatggca gcttttcgtt cttcgtcaag ttctaccaat tccccttcat tgagccgttc
     1501 tagtgccatt tcaaccattc ctacagcacc atctacaatc atcttacgtg catcaataat
     1561 ggcagatgct tgttggcgtt gaagcataac ggcagcaatt tctggagcat aagctaggta
     1621 agtgatacgt gcttcaagga tttccaagcc agcatcctca acacgacttt ggatttcttc
     1681 acgaatacgg ttagcaacaa tttcgctaga gccacggaga ctaccttcat ctgcttgccc
     1741 gtcacccgta gtatccacat taggagacac atcgtaagga tagatgcgga caatattacg
     1801 gagggcgcta tcacattgca atgaaagata ttttttgtag ttatcaacgt tgaagactgc
     1861 cttagcggta tcgacaactc tccaagttac cgcgataccg atttctacag ggtttcctaa
     1921 gcaatcattg attttttgac gagaattgct caaggtcatg actttgaggg aaatctgttt
     1981 cttgccaatt tcaagattta catcattgtc atttgatgat ttagctccta aaaaaggaga
     2041 ttttgtgcta acatcaccac tttgtccaag tcgagtgtgg tttgcagggt tgactgctac
     2101 gctgaaggga ttgacaaagt aaaaaccagg ttctttgatg gtacctgtat aattaccaaa
     2161 gagtgtcaga accagagctt cctgaggttt gacaactttt aaaccagcat gagctagacc
     2221 tgcaattacg attagtaaag gtccgataat aattccaaaa atgttttccg aaccaacacc
     2281 cattataaat ataaagatac caagtacgat tgtcaattca atgagaatca atgcgaatac
     2341 accatttggt tttgaattga tgagtttttc agtcataaga atgacctcct attatttgat
     2401 atctaaatga tatcactttg tttttaaaag tcaatagaaa gttgaaaata atcactaaaa
     2461 agtttcagcc caataatttc ttttaaaagg tgagattata ttgtgctcaa atactctttt
     2521 attcttataa tttttacact ataattgtag ttagaaagga agagaaatgt ttgattatag
     2581 agcactagtt attttgatga ctttgatgga tcattgtgag ctatcattat atgaattatc
     2641 tgttaaggtg agcttaccta taaaggaagt caaagaagga atagattatt tagtgcctta
     2701 tctagctaat aaagggatag tgctggataa aaaacaaggt cgctatagtt tatcaaatcg
     2761 tacgaagcag tctttgacag atattattaa gtcggatgaa ttggttttac caaagtcgac
     2821 tcgcttagct ttaatctatc tttacacttt ttgccgatta gattttatat cgaataatca
     2881 ttaccaagac tttttgaaag taagtaagaa tacaacctta tctgatattc aatcattaag
     2941 aaagattatg ttagataatg atttggagct agggtacagt agagcaaaag gttatacttt
     3001 acacggttca gagtggaata agcaccgctt agcttttcaa atggttagtg agttgctgga
     3061 atcctccata gggatttggg gtttggatta tgttttatcc agttgggggt attcattaac
     3121 ttatgatttg ataaatcagg tagttaaaga ttattatgag aagctacagc tagtacctat
     3181 tgttaatcaa ttaaaagttt gccttttcgg tttagtattc attctgtgta ggtatcaaag
     3241 ggatgttgaa agagtatgtc tttcagagac attagtatct cctgttattc aagatataac
     3301 gactatttta ttggatacag tggttgattt gggaattata gatacggtgt tttctgagga
     3361 tgattatcgc tatatcaccg ttttattatc aagttgcttt gaaggtgaag tagatgttgc
     3421 tccggtttac tttaatcaat taacagaggc tattataagt agaatggaag atatttcttt
     3481 gttacatttt aaacaaaggg aaggattgag agaaaatctt cgccgccacc ttataccggc
     3541 ttactataga ttaaagttcg gcctacctag ttcaaatgaa tatgtattgc atgttaaaga
     3601 acattatcct gatttatttg aattagtcaa agattctttg atgcccttga tggacgctat
     3661 tgacaatccc atacctgata gtgaaacagc atattttgtt atccatttcg gaggttattt
     3721 aaagaaagca gatactttgc ctcaaaaatg ctataaagca gcaatcattt gtcctaatgg
     3781 tgttagttct tcattgatgt taaaagagaa tctattagca ttatttcctc aaattgagtt
     3841 tataggaacc tcaaagattg atgatttaca ggtgaaagct agtagtgact atgatatggt
     3901 tttttctacc ataaaggtgg agacagaaaa gccaaattat ctagtttcgg ttatgatgac
     3961 tgaagagcaa gcaatacaac tagtagaact agtgttaaaa gattttccga atttagagta
     4021 tggggatttt gagattgaac aaatcctgaa tattgtcaaa agatatggaa ttattacaca
     4081 agaattggaa ttaagattgg cgttaaagaa ttatctttac caaaaaaatg atagaaagga
     4141 aattgtacca gtgctagaac aactcattac caaagaaacc tatcaggtta gttcgcaaaa
     4201 attaggatgg aaggaggcga ttcgtttagc agctaaaccg cttttggatc aagataagat
     4261 aactgagaac taccctgagg caatgattca aaaagtagaa gagtttgggc cttttattaa
     4321 tttagggaag ggagtagcaa ttcctcacgc tcggccagat gaaggtgtga atgaaatagg
     4381 aatgtcaatg ttagttttgg aagaaccgat ttatttattg gataatccag aacaagaggt
     4441 aagattgttg atttgtattg cagccattga taatgagagt catttaaagg ctttgtcaca
     4501 tttaacaaca attttaagag ataaaaatca tgttcaaact ttaatatcat caaaaaacta
     4561 tgatgacatt aaaatgataa ttaaacagga ggattagata atgttaaaaa ttggtacagc
     4621 ttgtggttca ggattaggtt caagttttat ggtacagatg aatattgaat ctgtattgag
     4681 tgatttgaat gtttcggatg tagaagttga acattatgat ttaggtggag cagatccaaa
     4741 tgcagctgat atttggattg ttggtcgtga tctagctgat tcagctagtc atcttggaga
     4801 tgttcgtatc ttaaatagta ttattgatat ggatgaacta cgagaattaa ttactaaact
     4861 ttgtgaagaa aaaggactta tataggaggc tagcgttatg atgaagttca tattggatat
     4921 tgttagtaca ccagctattt tagtagcttt aattgcaatt ttaggattag ttcttcagaa
     4981 gaagaaatta cctgatatta ttaaaggtgg aattaagacc tttgttggtt tcttagttgt
     5041 atctggtggt gcaggaattg tacaaaattc tttaaatcca tttggtacca tgtttgagca
     5101 tgcttttcat ttatctggcg ttgtgccgaa taatgaagca attgtagctg tagctttaac
     5161 aacatatggc tcagctactg cactgattat gtttgcaggc atggtgttca atatcttaat
     5221 cgctcgtttt actcgattta aatatatttt tttaacaggg caccacactc tatatatggc
     5281 atgtatgatt gcggtcattt tatcagttgc tggctttact agcttgcctc ttatcttact
     5341 aggaggatta gcactcggta ttattatgag tatttcccca gcatttgttc aaaaatatat
     5401 ggttcaatta actggaaatg acaaggtggc tttaggtcat ttcagttctt tgggatattg
     5461 gttgagtggt tttactggta gccttatcgg tgacaaatca aaatcaacag aggacattaa
     5521 atttccaaag agtttagctt ttttacgtga tagtactgtt agtatcactt tatccatggc
     5581 agttatttac attattgtag ctatctttgc agggtcagaa tatatagaaa aagaaatcag
     5641 tagtggtaca agtggtctag tttatgcttt acaattagca ggtcaatttg cagcaggggt
     5701 atttgttatt ttagcaggtg ttcgccttat tttgggcgaa attgttccag cctttaaagg
     5761 tatttcagag cgtcttgtac ctaattcaaa acctgctttg gattgtccga ttgtttatac
     5821 ttatgcaccc aatgcagttc taattggatt tatctctagt tttgttggtg gtttagtaag
     5881 tatggcaatt atgattgctt caggaacggt tgttatctta ccaggtgttg tgcctcattt
     5941 cttctgtgga gcgactgcag gtgtcattgg gaatgcatct ggtggtgttc gtggagccac
     6001 tattggagca tttttacaag gtattttaat cagttttctt ccagtctttt taatgccagt
     6061 tttgggagga cttggtttcc aaggatcaac tttctcagat gcagattttg gtctatcagg
     6121 aattatttta ggaatgttaa atcaatttgg ctcacaagca ggcattgtga ttggtcttgt
     6181 tcttattcta gcagttatgt ttggagtatc ctttattaca aagccatctg caaaggagga
     6241 ataagggatg attttaagta aaaataggga agatgagtta agaaaatttg cgactaacat
     6301 ccgattaaat actcttagaa cattgaatca tcttggattc ggacattacg gaggaagtct
     6361 gtctatcgta gaagttttag cagtgcttta tggtgaaata atgccaatga ctccagaaat
     6421 atttgcagca cgagatagag attatttcat attatcaaaa ggtcacggag gaccagctct
     6481 atacagtaca ctctatttga atggtttctt tgacaaagaa ttcttatatt ctttaaatac
     6541 aaatggaacc aaattaccgt ctcatcctga tagaaatcta acgccaggca tagatatgac
     6601 aacgggctct ttaggacaag gaattagtgt tgcaactgga cttgcatatg gtcagagaat
     6661 aagaaagagt cccttttata cttatgctat tgttggagat ggtgagttaa atgagggaca
     6721 atgttgggag gctatacagt ttgcttctca tcaacagtta tccaacttaa ttgtatttgt
     6781 tgatgataac aaaaaacaat tagatggttt tacaaaggat atttgtaatc caggtgattt
     6841 cgtagaaaaa ttttcagcat ttggatttga atccattagg gtcaagggtt cagatattag
     6901 agaaatttat gaagggattg tccaattaaa acagtcaaat aattcatcac ctaagtgcat
     6961 tgtattagat actattaaag gtcaaggggt tcaagagctg gaagaaatga aatccaacca
     7021 tcatcttcgc cctactgtag aggagagaca aatgttaact tcagttgtag aaagattaag
     7081 tcaggaattg gaggaaacag aatgatgaga agcacgaaag aattacggca tgtatataga
     7141 gacttccttt tagaggctaa tcaaagttat tctgatatag tagtcttaga agccgatttg
     7201 tcaagttcga tggctactaa taatcttgaa aaggattttg gagaccgtta tgtgaatgtt
     7261 gggattatgg aagcagaaat ggtcggcctt gcagcaggct tgtctattca ggggtttaga
     7321 ccttatcttc atacatttgg tccttttgct tcacgaagag tatttgatca attatttatt
     7381 tctcttggat acgcacaatt ggatgccact gtgattggat cagatgcagg agtaactgca
     7441 gaaatgaatg gtgggacaca tatgccattt gaagaaattg gattgttacg tttaattcct
     7501 aaatcgatca tttttgaagc aactgatgat atccaatttc gtgaaatatt gaaccagaca
     7561 ttagacttaa aaggactaaa atatattcga acaattagaa aagctccagt tcctgtgtat
     7621 caaggtggag aagatttttc taagggctac attgagttaa ggcatggtga agatcttgta
     7681 atcgttgctt ctggtataat ggttgctcca agtattcgag ttgcagatga actgtctaaa
     7741 ttaggttatt cagtaagtgt gatagattta tttagaatca aaccgatacc agaacagata
     7801 aaaacaatgt taagtggaaa aactatattt actgtagaaa accacaatca gataggtgga
     7861 attggcagtt ctttatgtga attattctct gatgatggaa tgacaaaaat tcatcggatg
     7921 ggtgttcaag aaagattcgg tcaagtaggg aaaatggatt atcttcttaa tgagtatggt
     7981 ttgagtgaat cgaatataaa agagaaggtt ctagaaattt ataatgcaag atagatgtta
     8041 aatacactta tctgaaagaa tttctgtaaa aattacagta cgttatttaa agaaagcgga
     8101 ttaaaaagca tattctggtc atcagaaagt gcactaatcc gctttgttgt ttttaatttt
     8161 aaatatttca catgtgtata gaattttctg aaaattcaag atttttattc tgttcttcat
     8221 gcgaaaattg tgctataata gtaaaaactg aaatgggagg gataagatga ctgaattaga
     8281 taaacgtcac cgcagtagca tttatgacag catggttaaa tcacctaacc gtgctatgct
     8341 tcgtgcgact ggtatgacag ataaggactt tgaaacaccg attgtgggag tgatttcgac
     8401 ttgggcggaa aatacaccat gtaacattca cttgcatgat ttcgggaaac tggctaaaga
     8461 aggtgtcaaa tctgcaggcg cttggcctgt acagtttgga accattaccg tagcagacgg
     8521 gatcgctatg ggaacgcctg gtatgcgttt ctctctaaca tctcgtgaca tcatcgcgga
     8581 ctccatcgag gcggctatga gtggtcacaa cgtggatgcc tttgtcgcta tcggtggctg
     8641 tgacaagaac atgcctggat ctatgattgc tattgctaat atggatatcc cagctatttt
     8701 cgcctatggt ggaactattg caccgggaaa tcttgatggt aaagatatcg acttggtttc
     8761 tgtctttgaa ggtatcggaa aatggaacca cggtgacatg acagctgagg acgtgaaacg
     8821 tcttgaatgt aatgcctgcc ctggccctgg tggctgtggt ggtatgtata ctgctaatac
     8881 catggcaact gctatcgaag ttctagggat gagtttgcca gggtcatcct ctcacccagc
     8941 tgaatcagct gataagaaag aagatatcga agcagcagga cgtgctgttg ttaagatgtt
     9001 ggaacttggt ctcaaaccat cagatatctt gactcgtgaa gcctttgaag atgctattac
     9061 tgtaacgatg gctctcggtg gttctacaaa cgccactctt cacttgctcg ccattgccca
     9121 tgccgcaaat gttgacttgt cacttgagga cttcaatacg attcaagaac gtgtgcctca
     9181 cttggccgac ttgaaaccat ctggtcagta tgtcttccaa gacctctacg aagtcggtgg
     9241 tgtccctgcg gttatgaagt acttgttggc aaatggtttc cttcacggag atcgcatcac
     9301 atgtactggt aagactgtag ctgaaaactt ggctgacttt gcagacttga ctccaggcca
     9361 aaaagttatc atgccacttg aaaatccaaa acgtgcggat ggtccgctta tcatcttgaa
     9421 cgggaacctt gctcctgacg gtgcagttgc caaggtatca ggtgttaaag tgcgtcgtca
     9481 cgttgggcca gctaaggtct ttgactcaga agaagatgcg attcaggccg ttctgacaga
     9541 tgaaatcgtt gatggcgatg tagtcgttgt tcgttttgtt ggacctaaag gtggtcctgg
     9601 tatgcctgag atgctgtcac tttcttcaat gattgttggt aaaggtcagg gagataaggt
     9661 ggccctcttg acggacggac gtttctctgg tggtacttat ggtctggttg ttggacatat
     9721 cgctcctgaa gctcaggatg gtggaccaat tgcctatctc cgtaccggcg atatcgttac
     9781 ggttgaccaa gataccaaag aaatttccat ggccgtatcc gaagaagaac ttgaaaaacg
     9841 caaggcagaa acaaccttgc caccacttta cagccgtggt gtcctcggta aatatgccca
     9901 catcgtatca tctgcttcac gcggagccgt gacagacttc tggaatatgg acaagtcagg
     9961 taaaaaataa actcatactc gaaaatctct tcaaatcacg tcaacgtcgc cttgccgtag
    10021 gtatggttac tgacttcgtc agttctatcc acaacctcaa aacagtgttt tgggctgact
    10081 tcgtcagttc tatccacaac ctcaaaacag tgttttgagc tgacttcgtc agttctatcc
    10141 ataacttcaa aacagtgttt tgagcaacct gcggctagtt ttctagtttg ccctttgatt
    10201 ttcattgagt atcaaaaagc aagccatttt cggcttgctt ttttcatctt taaaagtgat
    10261 tggcctgctt aacgaggtgg tagtccaagg gcaatacggc catagcgact gattcgtgtg
    10321 attttccaag caggcgacca ggtaacttca accttgatat ctttgatacc ctcgatttgt
    10381 ttcagacctg ccacaatttc aataggcagg ctttcggcgc aatcacaggc agtatcggtg
    10441 aaggtcatga caatcttgca gagccccgtt tcatccagat tgatttcata aatcagacct
    10501 agattgtaaa catccaattc cacatctgta tcaaaaactt tctctagttt ttcgataatt
    10561 tggtcttgca aggccaaagc acggtcattg attttgatat cgtctctcat agcagtccct
    10621 ccacgtgata aatatcctct attttctcat aattctgaca atttggcaag tttttgatga
    10681 attttctgaa aaataggata aaatgaagaa aatacggaat caaggggaag tctatggagc
    10741 agattggaaa agtctttaga caattacgag agtcaagaaa tatctcactg agacaagcaa
    10801 ccggaggaca attttcgccg tctatgttgt cccgttttga aacaggtcag agtgagcttt
    10861 cggtggaaaa gtttctattt gctctggaaa atatatctgc cagtgtggag gagatcctct
    10921 ttctggcgag aggtttccag tatgatacag attctgagtt gagaaaagaa attacagatg
    10981 tcttggaacc aaagaatata gcacctcttg aggacttata tcgcagggag tatcaaaagc
    11041 atgcccattc tcacaacaaa cagaaacata ttctaaatgc cattattatc aagtcttata
    11101 tgaagagcat ggatgaaagg gtagagttaa cagcagagga aggaaaagtc cttcatgatt
    11161 atttgttttc taccgagatc tggggaatct atgaactcaa tttattttca gtcagttctc
    11221 catttttatc tgtttctctt tttactagat atgtacgaga aatggtacgt aaatctgatt
    11281 ttctaatgga aatgtctggc aatcgaaacc tttttcatac tatactattg aatggctttt
    11341 tagctagtat tgagtgtgaa gaatttacca atgcctatta ttttaaacgt gttatcgaag
    11401 agcatttcta caaggaaaat gagacctatt tccgaattgt ttatctgtgg gcagaaggtc
    11461 tccttgatag caagcaaggt agagtcaagg aaggccagaa aaagatggag gatgctgtcc
    11521 gtatttttga gatgcttggc tgtaataaat ctgccgaata ctatagaaat acgaccgaat
    11581 gttgaatatc tgcaaaccaa gaaaaaattt gaagcgatag aactattgcc ctctctcagg
    11641 tcattacaaa agttctatcg tttctttttg ctcattttat ttgttgcata tattcaagag
    11701 ttctccctct caaatttcta agtgctatac tatagtcata cttcatatag aggttcgaac
    11761 aagaagggag attatctatg aaactattgt ttagaaatcc agcttataga attttgattt
    11821 tatcacgctt cttcaatgct tttggtgctt cgattttcaa cctggtcttt atcgtctatg
    11881 catcgacctt gtcacaagca tcttttgctg ttgctatggc gaatattgtc atgattcttc
    11941 cgaccctctt tacagttttt gtagggattc gggcagatta cacgagggac aaggtcaaat
    12001 ggatggtcta tagcggtttg tttcaggcgg ttctattttt tctagcagcc ctagttgttc
    12061 agcaagctag tctctttgcc ttttctagcc tgtgtttgat caatgtcatt agtgatatca
    12121 tcagtgattt tgcaggtggc ctgcgtatgc ctcttattaa ggaaaaagta gctgaagatg
    12181 atttgatgga ggcttattct ttttcacagt tcatcaccta tatttcagct attggtggtc
    12241 aagctttcgg agtctggctc ttagctctat cggtcaacaa tttttctctc gttgcgggaa
    12301 tcaatgcctg ctttttccta gtatcagcca ctatcctctt tttaggaaaa agcaaattga
    12361 gcctgtcaat gtcatctgct gatggtgaaa acttaaaaaa tgagaagctt tctatcaaag
    12421 accagttcct aacaatttac cgaaatttac gtctcgtttt tcttaaaagt gggcagaaaa
    12481 actttggttt tatgctcttt gctgtcttgc ttattaattc cttgggtggc gctttgggtg
    12541 gaatttataa tatcttcttt ttgagccatt ctctcttgaa tttttcttat acagaggcac
    12601 tatttatcaa tcaattctgt gttttagtag caatcatcat cagtagcctt acgggcaatg
    12661 attattttgg gaagcagtcc ttgcctagat tgatgatgtg ggcgaccgta ggacttagtc
    12721 tagttggttt ggctaattta ttcaatcaag tcgtgcttgg tttgctattt ctcttcttta
    12781 ccctgtatgt gtctggtaaa gttcaaccaa agattagtgc catgctcatg aaaaatctag
    12841 ctccagaggt tctagctcgt actagtaatt ttttaggtct attgtttacc ttatccatac
    12901 ctgtgggaac agcttgtttt tcactagtag ccgtatggaa tatacagttg acttggatgc
    12961 tatttgttgg tctttccttg ctagctattt ttttgacaat tcttaatctc aaaaatgata
    13021 tctaaatcct aatttttttc ttactgtttt aatcccttta tttgtggtaa aataagacta
    13081 ttaagtttaa agaggattcc ctatgaaatt acaaaaacca aaaggaacgc aggatatttt
    13141 acctgctgaa tctgctaagt ggcagtacgt tgagggcttt gcccgtgaga ttttcaagcg
    13201 ctataactat gcagaagtgc gcacgcctat ttttgagcat tacgaggtta tcagtcgctc
    13261 tgtcggagat acaacggata tcgtaaccaa ggaaatgtac gatttttatg acaagggtga
    13321 ccgtcatatt accctccgtc cagaaggaac tgcgcccgtt gtccgttcct atgtggaaaa
    13381 taaactcttc gccccagaag tgcaaaagcc aagcaagttc tactatatgg gacctatgtt
    13441 ccgttatgag cgtccacagg cagggcgctt gcgccaattc caccaaattg gtgttgagtg
    13501 ttttggctct agcaatccag ctaccgatgt ggaaacaatc gctatggcag cccatttttt
    13561 gaaggaaatc ggtattcaag gtgtcaaatt gcacctcaac actcttggaa atcctgagag
    13621 ccgtgcagcc taccgccaag ccttgattga ctatttgaca ccgctcaagg agaccttgtc
    13681 taaggatagc caacgtcgct tggaggaaaa tcctcttcgt gtcttggact ctaaggaaaa
    13741 agaagacaag gaggcagtag agaatgcgcc gtctatcttg gactttcttg atgaagaaag
    13801 ccaagctcat tttgatgctg tgcgtcagat gttggaaaat cttggagtag attacatcat
    13861 cgataccaat atggtgcgtg gtctggacta ctacaaccac accattttcg agtttatcac
    13921 agagattgag ggcaatgacc tgaccgtctg tgcgggtggt cgttacgatg gtttggtttc
    13981 ttattttgga ggccctgaaa ctgctggatt tggttttgga cttggtgtag agcgcctgct
    14041 tctcattctt gaaaagcaag gtgtgaccct ccctatcgaa aacgccctag atgtctatat
    14101 cgcagtcttg ggcgaagggg caaatatcaa ggccttggaa ttggtacagg ctcttcgcca
    14161 acaaggtttc aaagcagagc gtgattacct caaccgtaaa ctaaaagctc agttcaagtc
    14221 agccgatgtc tttgtggcta agaccctcat caccctagga gagagcgaag tcgaaagcgg
    14281 acaagtgacg gtcaagaaca accaaactcg agaagaagtg caagtgtcac ttgagacaat
    14341 cagccaaaac ttctcagaaa tctttgaaaa actaggattt tatactcaat aaaaatcaaa
    14401 gagcaaacta ggaagctagc cgcaggttgc tcaaaacact gttttgaggt tgtggataga
    14461 actgacgaag tcagctcaaa acatggtttt gaggttgtag atgaaactga cgaagtcagt
    14521 aaccatacct acggcaaggt gaagctgacg tggtttgaag agattttcga agagtattaa
    14581 tgatagataa agtggtcagg aacttactcc tgaccttttt cttttgcaaa atgacaaaaa
    14641 tcataaactt tttgacaaat atacttgtca aaaagaaaaa gatatgttac aatgaattca
    14701 agttaagaaa taggaagcag aaaggagtta taatgtgggt actaggattt atactattta
    14761 tgattttctt ttattctaat aattctaaaa aaatcaagaa actagagaat aaaatcaaaa
    14821 aacttgagcg aaaagagaaa ggaaacgcag aaatgtcgag attattacaa gaaatgattg
    14881 gaaaggaacc aattataacg ggagtgtata ttgggccaga taactgggaa gttgtggatg
    14941 ttgatgagga atgggtcaaa ctacgtagtg ttgataatac gggaaaagaa aaattcaagt
    15001 tgcaacgtat tgaagatatc caaaccgttg aatttgacgg agagtaggtg tgtaacgtgc
    15061 aactaaaaaa tcgtctaaaa gagcttcgag ctcgcgatgg tctcaatcaa accgacctag
    15121 ccaaactggc aggggtttcc agacagacca ttagcctact agaacgggat gagtacaccc
    15181 catccattat cattgccctg aaaatatctc aaattttcaa cgaaacagtc gaatcggtat
    15241 ttcgtttgga ggaggacgag tgatgaacaa gtataaagtg atttattatg tagtggtcat
    15301 agctttatta gtcagcgtat ttctactgat tgggatggac ctaagctggt ttaatcccta
    15361 tcaaggcgac caatttgttt ggctctactt tgctctcatc ccagtaattg aatggattga
    15421 aaagaaatcc aaaaatctag caagtgaaaa aggagaatga atatgaaaaa gaaacgtaga
    15481 ttgttatttt tgatgtctat tgtcttgggg gggttcttgg gcatgtttgt agggatgttt
    15541 aaggcacgtg tcgaatccca cgaaattatt ttagatgtaa aagccttgat gccatggata
    15601 tcagctattt gtttactgat aggtttcatt agtatgtttt tgactttcaa tttcttaaag
    15661 aaaagcagaa aatttcattc cttgtatcaa gaggaaatgg atgacgatct gaatgaaacc
    15721 tattatgtgc aaatgtatcg gaatcttgag tttggaacca ttgcttttaa tattacaggt
    15781 gtagcgattc cattggctat ttttatttca ttaagtgagg tgattatatt gcatacaaac
    15841 cctcaaacat ttttcctttc tttcttactc tttgtggtat tcttagtcgc tcaaaaatct
    15901 ctttttaaaa ccattgcgat tgttcgtcag tttgatttgg aatttttcgc tacaccaaag
    15961 gatgtcttga actatataaa ttcttatgat gaaggggagc gtcaggctaa tttggaacag
    16021 agttttcgaa ttttattcca attacaccaa tatgtcttac cagccttata tatttttctt
    16081 attatcattt ctttcttgac aggagagatt cagttactag ctttcttgct tgtaggagcc
    16141 atccatgttt atatcaatgt gatgcagtta cctatggtaa aacgttattt caaataaagg
    16201 agttatctat gaaattactt aaaaaccttg gctggattct tctagccctt ctatcctttt
    16261 tatttatcta tggctttatt caggggctcg cgactgcgtc gcttgcttta ggcgcttcac
    16321 cctatgctgt tactctactc tatgtggcct tggctggagt atatgtgtac ggcatttaca
    16381 aatggtatca gaaggctcct gttcatattg agaagagcgg ctttaaccga tttatttggc
    16441 ttcctgcctt ggtttggttc ttatctctgg tcgttcaatt cttcttgcca gatgatcctt
    16501 cagtaaatca gcaaatagcg acagacttga ccttgtctca accacttttc tcattctttg
    16561 ctgtggttat ttttgctcct ttgacggaag agattgtttt tagagggatg ttagcacgct
    16621 atctctttcc taagcaggac aatagtaaac gaaccctgat ttttcttctg gtatctagtc
    16681 ttctatttgc cttgattcat tttccaggtg atgtgcaaca attttttgtc tattttagcc
    16741 ttggttttag tttgggcttg gcttacatta gcagaaaagg tctggtctac agtatttctc
    16801 ttcacgcttt gaataattta gtcggctttt tgatgattct catgctataa tagagtcagg
    16861 aggtcacatg aaacgagtaa ttttattagc agtgattcag gcagtcgttc tatttttcat
    16921 cattggagcg ctagcttatg ccttcaaagg cgatttcttc tataactatc tagcagttgt
    16981 ctttgctcct attgcaggtg tactgcgttt tgggacggct tacataacgg aaattgtctt
    17041 gcctcgaaag gcagccgaaa tcgctgaaaa gcgtaaagca ggcaaaaatt caaaataaaa
    17101 gagtccggtg aagttcatcg gatttttgta ttatactcaa tgaaaatcaa agagtaaact
    17161 aggaagctag ccgcaggttg ctcaaaacac tgttttgagg ttgtagatga aactgacgaa
    17221 gtcagctcaa aacatggttt tgaggttgta gatgaaactg acgaagtcag taaccatacc
    17281 tacggtaagg cgacgctgac gtggtttgaa gagattttcg aagagtatta gcgctaattt
    17341 ttagggcttt cacttgactt ttaaagactg gcaaactttt ctgatgattt tcatgaagag
    17401 cctgcgcttt tatggtaaaa tagtaacaga ataaaagagg agagaaataa tgaaacgtag
    17461 tatgtatgct ggtcgtgttc gtgaggaaca catcggacaa gaaataacct tgaaaggatg
    17521 ggttggccgt cgtcgtgacc ttggtggttt gatctttatc gatcttcgtg accgtgaagg
    17581 aatcatgcag ttggttatca accctgaaaa agtatctgca gaggttatgg caacagctga
    17641 aagccttcgt agcgaatttg ttattgaggt gactggtcag gtcgctgcgc gtgagcaagc
    17701 caatgataag ttgccaactg gtgcggttga gttaaacgtg acagctctta ttgtgcttaa
    17761 cacagctaag acaacaccat ttgagattaa ggatggcatt gaggcaaatg acgatacacg
    17821 tttgcgttac cgttaccttg accttcgtcg tccagaaatg ttggaaaatc ttaaacttcg
    17881 tgccaaggtg acccactcta tccgcaacta tttggatgag ttggagttta tcgacgtgga
    17941 gacaccattc ctttctaagt caacgcctga aggggcgcgt gattatttag tgccgtctcg
    18001 tgttaataag gggcattttt acgctcttcc tcaaagtcca caaatcacga aacagctctt
    18061 gatgaatgct ggttttgacc gttactacca aatcgttaaa tgtttccgtg acgaggactt
    18121 gcgtggagac cgccagcctg aatttactca ggtcgacttg gaaacgtcct tccttactga
    18181 gaaagaaatc caagatatta cagaaggctt gatcgcgcgc gtgatgaagg aaacaaaagg
    18241 catcgaagta acgctaccgt tccctcgtat gaaatacgat gatgctatgg ctctttacgg
    18301 ttctgacaag ccagatactc gttttgacat gttgcttcag gacttgacag aagtggtcaa
    18361 aggtgtagac tttaaagtct tttcagaagc acctgctgta aaagcgattg tggtcaaagg
    18421 agctgcggac aactattcac gtaaagacat cgacaagatg acggaagtag ccaaacagta
    18481 tggtgccaaa ggtcttgctt gggtcaaggt ggttgatgga gaattaaacg gaccagttgc
    18541 caagttcttg actggtatcc aagaagaatt gacaacagcg cttgctcttg aagataagga
    18601 cttggttctc tttgtggcgg atacgcttga agtggctaat gcaacactgg gtgcccttcg
    18661 tggacgtatt gctaaagagc ttggcttgat tgataatgat aagttcaact tcctttgggt
    18721 ggttgactgg ccgatgtttg aatggtctga agaagaaggc cgctacatga gcgcccacca
    18781 tccattcaca cttccacagg aagagactgc tcacgaatta gaaggtgatt tggctaaggt
    18841 tcgtgccatt gcttacgata tcgtcttgaa cggttatgag cttggtggtg gtagccttcg
    18901 tatcaaccaa aaagaccttc aagaacgcat gttcaaggct cttggtttct caactgaaga
    18961 agccaatgac cagtttggtt tccttcttga agccatggac tatggtttcc caccacacgg
    19021 tggtttggct atcgggcttg accgttttgt catgttgctt gctggagaag aaaatatccg
    19081 tgaagtcatt gcctttccta agaacaacaa ggcaactgac ccaatgacac aagctccatc
    19141 aacagtcgct ctcaaacaac tagaggaact cagcttacaa gtagaagaag atgaaacaaa
    19201 caaaacgaat taagcggtgg cgctattatc tgcgccgctt tgcttatcag ataaaaattt
    19261 tacgtgtctt acaaagtatc tctcgagaaa agtatgatga gaagatttcg gcctctctgg
    19321 tctatggttt tttatcagca gtagcagtta atttcttttt ccaaccaggg catgtgtatt
    19381 cgagtggtgc aacaggtctg gcacagatta tctctgcctt gagtaatcac tggtttggtt
    19441 ttcatattcc gatttcgcta agcttctacg ccattaactt ccctttgatg gtcttagctt
    19501 ggtatcagat tggccataag ttcaccgtct ttacctttat cacggtatct atgagttcct
    19561 tctttatcca gtttgtccct gtggcaacct tgacggagga tcccattatc aattcccttt
    19621 ttgggggtgt tgttatgggt ttggggattg gttttgctct tcgaaacaat atctccagtg
    19681 gtgggacgga tatcgtcagc ctgactattc gcaagaaaac gggtaagaat gtcggtagta
    19741 tttctttctt ggtaaatgga actatcatgc tgatagcagg tttgaccttt ggttggaaat
    19801 acgctcttta ttctatgatt accatctttg tctctagccg tgtgacagac gcagtcttta
    19861 ctaagcaaaa gcgtatgcag gccatgattg tgacaaatca tccagagaag gtaattgaaa
    19921 aaatccataa aaaattgcac cgcggagcaa ccatgatcca cgatgcagaa ggaacctata
    19981 atcacgagag aaaggcagtt ttaatcactg tcattacacg tgcagagttt aatgaattta
    20041 aacagattat gacacaagtg gatccaagct cctttgtctc tgtctcggaa aacgttcata
    20101 ttctaggaag atttgttgag atagataatt agtgattaat actcttcgaa aatctcttca
    20161 aaccacgtca gcttcacctt gccgtatata tgttactgac ttcgtcagtt ctatctgcaa
    20221 cctcaaaacc atgttttgag ctgacttcgt cagttctatc tgcaacctca aaaccatgtt
    20281 ttgagctgac ttcgtcagtt tcatctacaa cctcaaaacc atgttttgag ctgacttcgt
    20341 cagttctatc cacaacctca aaacagtgtt ttgagcaacc tgcggctagc ttcctagttt
    20401 gcactttgat tttcattgag tataaaaaga tcttgggaaa agactcaatt tcagtagaaa
    20461 aggaagtaaa tcttcccaca ataaaacgca tagtatcaag ttttttcaat acctgatagt
    20521 atgcgttttt gcttttaacg actctttgcc cagtctctta tttttcgata attttgtggg
    20581 cgatcaattg acggtaacaa atttgtttat tgtttttatt atcattaata atctggagaa
    20641 tagtttcaag ggaaacacga ccaagctcta aactattgat atcgacatag gctgccaagt
    20701 tgagcttggg attaaccgag tcaaagctga gaacagggac atccagctgg tgtttggcaa
    20761 tatagttaca aacaccttca gctaggaggc tatcggttgt gatgatagca tcaatttgtg
    20821 gatcgtgctt gaataatcgc ttgctaaatt tatagccctt ttcttccaga aactcgtcgg
    20881 caaagtagat gcgattgttg tcagtggtaa gtttgtaatg tttaagcgcc tgttcatagc
    20941 ccgttaaacg gtctttggtc acgaagacct ttttacttcc tccgataaag gcaatgcgtt
    21001 tgcagccttt tttgatgaaa tattcagtcg catcaaaacc agcttgaaca ttgtcgttgt
    21061 cgacaagtgg gatgaaagga gatagagatt tacctaagat aaggaagggg aactgttctt
    21121 ctgcgacgag ttttacgaga gggtcttctt cttgggcata gagaaagatt agcccatcta
    21181 cacgcttgcc gtagaccatt tgtgaaatag cgttgagacg ctccttctca tctttccctg
    21241 ttgctatttg aatggcatag tggttttcag atgcgacttg agagatgcca cgtagaaccg
    21301 atggaaagaa aggattctgg tagaaggcgt ctgagtcatc aggaagaact aatccgataa
    21361 cctgagtata gctgcttacc aagctacgag cgttaaggtt tgggtggtag ttgagttcct
    21421 tcatagcttt gcgaacgcgt ttttttgttt cgtcgctaat ggttgattta ttttgaataa
    21481 cacgggttac ggttgaaggc gaaacaccag cagccttggc cacgtcttta atcgtaacgg
    21541 gcataaaaat ctcctattta tggtaatttg gatcacggaa atgtgtttta taaaagatag
    21601 tgaccagata cagaacaaaa agaatatttt gtacagtaat cagggttgtc atattttggc
    21661 caaataatcc caaaataagt gtaatcagag tcggcaatcc taaacagttc aagataaagt
    21721 gatagcactc tttaaaggtt ctaaatgaaa agaggcgtga tttcttagtg atataaagga
    21781 gaagactagc tcctagagag acgataaaga aattcaaacc aaagaggaag ctcgcaccga
    21841 gaactaggaa gaggctgata tagacacgat tttgttggta ccagtcttta gaaattgctt
    21901 gggtcaagct gtctttgctt ttgaaactct cagtctgaat ggctcggtaa gagatgcggg
    21961 tcagttcctt gctttccttg ctgatgacta gttcatttgt atcgaaatgc agttgcaagt
    22021 ccttaggtaa ttccttgatt tgacctggac caatcacaac agaaggggct tgactagctg
    22081 ttccagtata agttaatgtg ccatcgacaa ttgtagcatg ttcagagaga tcctggacaa
    22141 cctcatttgt cagaggttca tagacattat cgataaaagt ttctagcgga taggtctcct
    22201 gggagctgtt ttggatagca atgggtacca tagacaagct gataaggaag atactggtaa
    22261 agagaagttg aaaccagttg agctcgaaac gtttggacag gggcttacga aacccccaaa
    22321 tacttgaaaa ataggaaaat ggatatggaa gcataggtat ctttctaaaa ggtgttttct
    22381 atatgagtat tattatatag agaaatgcgc tttatttcaa gtctaggggg taaattgctt
    22441 gctacaagga tattatttac agtgacaatc gctaatagtc aatgaaaatc aaagtgcaaa
    22501 ccaggaagct agctgcaggt tgctcaaagc acaactttga ggttggagat aaagctgacg
    22561 tggcttgaag agattttcga agagtataaa atgaaaaagg gtggcgggga taaattatcc
    22621 cttgtcgcca ccacttgtaa gtcctgaaac aaagttcttt tgtaggaaga agaagagaat
    22681 acagattgga agggcgatga ggatagcacc tgctgagaag taggcaatct tcaagttttt
    22741 cgcattgtta acgaaggttt ggagacctac ggcaacagta aagtattctt tctcacgaag
    22801 caagaaacta gagaggatgt agtccccgaa aggtcccatg aaggcccaga gagcttgtac
    22861 ggcaaccatt gggcgaacaa gtggtagaac aatttgccag aagcggcgga agtgtcctgc
    22921 accgtctagt tttgcagatt cgtctaaaga cattggcact gtatcgaagt agcctttcat
    22981 gagccaagca ttcatcggga taccaccacc aacgtagagg aagatgagga accagttgtg
    23041 gttaagggcg ttcaacataa gcgccataac gaagaaggct gtcaaagcgg ccatagttgg
    23101 caccatttgg atgatcaaga agaagaccaa actttgttta cgagccaaga agttgtaacg
    23161 gctgtaagca taaccagcaa gtacgatgat acttgtttga acagccatgg taattaaggc
    23221 gataatcaaa gtgttgaggt accaagtacc gtacaaggtt tcagtgaaga ggcctttaaa
    23281 gttatcaaaa ttgaggtcga tattagtatc tagtttaaag gctgagacgt tacctgcttt
    23341 aaaggctgac atgatggtaa tcaacagtgg atagataatt acaattgata gaccaatcag
    23401 gtaaaggtaa gtaaggcttt gagtcagtct acgtttgagt ttaattgagt tattcatctt
    23461 agacgtcctc catatcaaat gcgtgtagtt tcttgaatgc gatcatagag attgagatga
    23521 caatgataga gataatcaag gtaacagctg ccgccattga gtattgagga gatgtacctg
    23581 ttgtcaaacg gtagatccat gagatcaaga tatcggttga accagctcca cctccgacac
    23641 taccaggtcc tccaccattg aagaggtaca tgatagagaa gttgttaaag ttgaaggtgt
    23701 attggctaat caaagtaggt gccgcaacag ccaaaatcat tgggaaagtg atgttgcgga
    23761 atttttgcca agcgttggca ccgtcaatat aagctgcttc gtaaaggtcg ttaggaatag
    23821 attgcaagat acccaaagtc aaaacgtaga tgtatgggaa tccgagccaa ccttgcatca
    23881 taatcaaggc aatcttagtc caagttgggt ctgttttcca aggaataaga gctccatcaa
    23941 ggaaaggaag gaatttagcc aagattggca atacttgagt gttgatagca ccgacactat
    24001 cgttaaacat gtttgagaat gtcaagatag tgatgaaggc tgggacagcc caaggaagaa
    24061 ggaaaataac accaaagata cgttttcctt tgataaatgg ttggttggca atgatagctg
    24121 tgaagatacc aattacgatt tgtaaagtag aagctgccaa agcccaaatg atagtccaag
    24181 aaagaacaga accaaaggca gaacggaagg tactcaagct ccaaatgttt gtaaagttgg
    24241 tcaaaccaac ccagtccaac aacttgtttg gtggcaagtg ttggaagtcg tagttggtaa
    24301 aggcgatcat caaggttacg ataactggga agataatcgc gaaggtcatg gcaacataag
    24361 atggaatgat caagaggtaa gggaagccat tttcataaat ccctttgatc atgtctttga
    24421 gtgtgcgtgg aactggaatt ccattgttaa tgcgttttgc aatcgtatgt gcatctttga
    24481 tatttgagaa ataaaagagt acataaacga ttacaaagat tagatggaag gcaccacgaa
    24541 tcagcataaa gagggaatta tcacgacctg gtttgtcacc aagagtgatg aggttgctca
    24601 attcaggggt tgcaagtgct aggaagtaaa ggacaaatac gatggttaca ccaaggaaga
    24661 taaaaccttt ggctttttgt ttattgtaaa tctgtcctaa cccaggaatg atagacagca
    24721 gggctgcttt actaggttgt tgcttttcca tattaactcc tttcatagga tactactttt
    24781 ttataagaaa gctaaattat ttgtgtctct attgataaat tcaaaggggg atttgatttc
    24841 cacccccctt gaacaaattt tttattcacc aaatttttgt ttgattgttt ctttgatcaa
    24901 tgttacagca tcgttagcag ctgttttagc atctttttga ccacttacag catcaaagag
    24961 catatttttc gctggatccc aaactgcaga catttgagag atgtttggca gtggttgagt
    25021 gttcttgaac tgtttgataa cagctgttgt caactcatcg tttttacctt cagcgtatga
    25081 acgagcctca gtattagctg ggatttcgtt agtcttatca tataatactt tttgttgttc
    25141 agttgcaaca aggaagtcta caaatttttg agaagcttca aggttcttaa cggcttgagg
    25201 aatgacccaa gctttaccac caccgaatgc agcatattct tttccatttg gaagagttgg
    25261 gatagttgca actccgtagt ttactttagc atctttaaag gcttgagctt tccaaggtcc
    25321 gtcgatgata gcagctgttt taccttcttg gaattgagtt tggattaagt ttccagcacc
    25381 ttctgtatct tgcatacctt taggccattt ttcgtaccaa gatttagcgt agttgatacc
    25441 tgcgatagaa ccgtcgtttg caagaccgat gtctttagcg tctttaccgt tttggccaaa
    25501 gacgtaagca ccgttaccgg caagaagtcc atatgtatag tagaagtttg tccagtcagc
    25561 taggaaggca gtagttttac catcttcacc agcgaatgcg tatttgctat ctttagcaag
    25621 gttttccaag tcagcaaatg tttttggagc atctttcacc aagtctttgt tgtagtacat
    25681 aacaagtgac tcgataacgg caggagcacc gtaaacttta ccattagcag ctgttacaag
    25741 agatttagtt gtgtcgtctg ttttagcacc atcgctcaat ttcacttctg aaagttgtcc
    25801 gtcagaacca aggctaccta cacggtcgta tggagccatc ataacatcag ggacattacc
    25861 agattggttg tcaagagaaa gtttatcaag acctcctaga gcatcaccag ttttaagagt
    25921 gacttttact ccagcttctt tttcataagc tttagcaacc tcttcaatat agctcttata
    25981 tccctcgtct acatatacag tgagttcttt gacttcagat gaaccagaat cagcaggctt
    26041 atcagcagtt ttgcttccgc aagctaccaa aagcaagcta gcaagtgtag cagttccaag
    26101 caccgcagtg ctcttcataa atttagatga catagtgtat tcctcccaaa gaatagcaag
    26161 ttttattgat aaggaaacgc aaacgttttc ctttatgagc ttagtatagc acaaatagaa
    26221 aacggttgca agtatttttt gtaaaaattt taaaaaattt ttaagcttga tttgatagca
    26281 taattttgca ttttaataga agaaaagtat gaaatagata agaatacagt atttttaata
    26341 aaaatatatg gaatctgtct aaagagggaa atcaggaggg gctacctccc tgtttctaat
    26401 ccctatctat tttctataga cgtttgtgct ttgttgcata taaattcaag ctccctaagg
    26461 aggttttgta ctttgtagac tgtctcgtga gagtcaaact ttaggattag atagttttaa
    26521 gttatctttg ctaaaatgag ttagtctcct taaaaataat caaaaaagtt ttttaaaaac
    26581 gcttgcaatt atgcttgaaa aggagtatac ttataagtaa cgcaaacgtt tgcgtctgca
    26641 aaatacgcaa cgttccatta ttttaacaca cgaggtgcta ttatgaaaaa acgtcaaagt
    26701 ggtgtgttga tgcacatctc ttctcttcca ggagcttacg gaatcggatc atttggtcaa
    26761 agtgcttacg acttcgttga tttcttggtc cgtacaaaac aacgttactg gcaaatcctt
    26821 ccattaggag caactagtta cggggattct ccttaccaat ctttctcagc cttcgcagga
    26881 aacactcatt ttatcgattt agatatcttg gtggagcaag gtttgttgga agcaagtgac
    26941 cttgaaggag ttgactttgg tagcgatgcg tctgaagttg actatgctaa aatctactat
    27001 gcacgtcgtc ctcttttaga aaaagcggtg aaacgtttct ttgaagtcgg agatgttaaa
    27061 gattttgaga aatttgctca agacaaccaa tcatggcttg agctctttgc tgagtatatg
    27121 gctatcaaag agtattttga caatcttgct tggactgaat ggccagatgc agatgctcgt
    27181 gctcgtaaag cttcagcact tgaaagctat cgtgagcaat tggcagacaa gttggtttac
    27241 caccgtgtga ctcaatactt cttcttccaa caatggttga aattgaaagc ttacgctaac
    27301 gacaaccaca tcgaaatcgt tggggacatg ccaatctacg tagcggaaga ttcaagtgat
    27361 atgtgggcaa atccacatct cttcaaaaca gatgtcaatg gtaaggctac ttgtatcgca
    27421 ggatgcccac cagatgagtt ttctgtaact ggtcagcttt ggggtaatcc aatctatgac
    27481 tgggaagcaa tggacaaaga cggctacaaa tggtggattg aacgcttgcg tgaaagcttc
    27541 aaaatctacg atatcgttcg tatcgaccac ttccgtggct tcgaatctta ctgggaaatc
    27601 cctgctggtt ccgatacagc agcacctggt gagtgggtga aaggtccagg ctacaagctt
    27661 tttgcagccg ttaaggaaga acttggtgag ctaaacatca tcgcagaaga ccttggcttc
    27721 atgacagatg aagtgatcga attgcgtgaa cgtactggct tcccaggaat gaagattctt
    27781 caatttgcct tcaacccaga agacgaaagc attgatagcc cacacttggc acctgctaac
    27841 tcagttatgt acacaggaac acacgataac aatacggttc ttggttggta ccgtaatgag
    27901 attgatgatg cgactcgtga gtacatggct cgttacacga accgtaaaga atacgaaaca
    27961 gtggtacacg ctatgcttcg tacagtattt tcatcagtta gctttatggc aattgcaact
    28021 atgcaagatt tactagaatt ggatgaggca gctcgtatga acttcccatc tacccttggt
    28081 ggaaactggt cttggcgtat gactgaagat caattgacac cagctgtcga ggaaggtttg
    28141 cttgacttga caacaattta tcgccgaatt aatgaaaatt tggtagattt aaagaaataa
    28201 gacaataatc aggagacaac taaacatgtt atcactacaa gaatttgtac aaaatcgtta
    28261 caataaaacc attgcagaat gtagcaatga agagctttac cttgctcttc ttaactacag
    28321 caagcttgca agcagccaaa aaccagtcaa cactggtaag aaaaaagttt actacatctc
    28381 agctgagttc ttgattggta aactcttgtc aaacaacttg attaaccttg gtctttacga
    28441 cgatgttaaa aaagaacttg cagctgcagg taaagacttg atcgaagttg aagaagttga
    28501 attggaacca tctcttggta atggtggttt gggacgtttg gctgcctgct ttatcgactc
    28561 aattgctact cttggtttga atggtgacgg tgttggtctt aactaccact ttggtctttt
    28621 ccaacaagtt cttaaaaaca accaacaaga aacaattcca aatgcatggt tgacagagca
    28681 aaactggttg gttcgctcaa gccgtagcta ccaagtacca tttgcagact ttactttgac
    28741 atcaactctt tacgatattg atgttactgg ttatgaaaca gcgactaaaa accgcttgcg
    28801 tttgtttgac ttggattcag ttgattcttc tattattaaa gatggtatca actttgacaa
    28861 gacagatatc gctcgcaact taactctctt cctttaccca gatgatagtg accgtcaagg
    28921 tgaattgctc cgtatcttcc aacaatactt catggtttca aacggtgcgc aattgatcat
    28981 cgacgaagca atcgaaaaag gaagcaactt gcatgacctt gctgactacg cagttgtcca
    29041 aatcaacgat actcacccat caatggtgat tcctgaattg attcgtcttt tgactgcacg
    29101 tggtatcgag cttgacgaag caatctcaat tgttcgtagc atgactgcct acactaacca
    29161 cacaatcctt gctgaggcgc ttgaaaaatg gcctcttgaa ttcttgcaag aagtggttcc
    29221 tcacttggta ccaatcatcg aagaattgga ccgtcgtgtg aaggcagagt acaaagatcc
    29281 agctgttcaa atcatcgatg agagcggacg tgttcacatg gctcacatgg atatccacta
    29341 cggatacagt gttaacgggg ttgcagcact tcatactgaa atcttgaaaa attctgagtt
    29401 gaaagccttc tacgaccttt acccagaaaa gttcaacaac aaaacaaacg gtatcacttt
    29461 ccgtcgttgg cttatgcatg ctaacccaag attgtctcac tacttggatg agattcttgg
    29521 agatggttgg caccatgaag cagatgagct tgaaaaactt ttgtcttatg aagacaaagc
    29581 agctgtcaaa gaaaaattgg aaagcatcaa ggctcacaac aaacgtaaat tggctcgtca
    29641 cttgaaagaa caccaaggtg tggaaatcaa tccaaattct atctttgata tccaaatcaa
    29701 acgtcttcac gagtacaaac gccaacaaat gaacgctttg tacgtgatcc acaaatacct
    29761 tgacatcaaa gctggtaaca tccctgctcg tccaatcaca atcttctttg gtggtaaagc
    29821 agctccagcc tacacaatcg ctcaagacat tatccattta atcctttgca tgtcagaagt
    29881 tattgctaac gatccagcag tagctccaca cttgcaagta gttatggttg aaaactacaa
    29941 cgttactgca gcaagtttcc ttatcccagc atgtgatatc tcagaacaaa tctcacttgc
    30001 ttctaaagaa gcttcaggta ctggtaacat gaaattcatg ttgaacggag ctttgacact
    30061 tggtactatg gacggtgcta acgtggaaat cgctgagttg gttggagaag aaaacatcta
    30121 catcttcggt gaagattcag aaactgttat cgacctttac gcaaaagcag cttacaaatc
    30181 aagcgaattc tacgctcgtg aagctatcaa accattggtt gacttcatcg ttagtgatgc
    30241 agttcttgca gctggaaaca aagagcgctt ggaacgtctt tacaatgaat tgatcaacaa
    30301 agactggttc atgactcttc ttgacttgga agactacatc aaagtcaaag agcaaatgct
    30361 tgctgactac gaagaccgtg acgcatggtt ggataaagtc atcgttaaca tttctaaagc
    30421 aggattcttc tcatctgacc gtacaatcgc tcagtataac gaagacatct ggcacttgaa
    30481 ctaatactct tcgaaaatct cttcaaacca cgtcagcttt atctgcaacc tcaaagcggt
    30541 gctttgagca acctgcggct agcttcctag tttactcttt ggttttcatt gagtataaga
    30601 tacaaattta tactaataca ttttgtaaaa aagcgagttt cgattgaaat tcgctttttt
    30661 aaatgctgta gatttgggtc aatcttgtct aaaaataggg aaatcctaga tacagtgaag
    30721 actttaaatg ctggttttta ctgtcctcag ccttatattt tttcgtagtt gattacctca
    30781 cacctcttgt attcgcttac ataaagtatt ataatataat tgtaggaaag aaggtgtttt
    30841 tatgatatac acacttaaat tggtgttgtt tattaccttt cttgtaataa gcttgttacc
    30901 tgataagatt tttggaaaaa ataaaaaaat ttggaaaata gtttttgcaa tattgacggc
    30961 agtggcagca ttgtcattta tgtactaagt tattttaaga atgtagggaa ataaacccta
    31021 cattcttttt agttttttct gttttctaaa ttctatttat ccaagcgctt caacatttct
    31081 tgcttcttcg cttcaagttc tgcacgcttt tcttcgattt cggcatgttt tttctcgagt
    31141 tcagaacaac ttgcaccatt gctaaattct tttcgccatc aggagatagg gtgagtcgac
    31201 atgtctatta ctcacccaaa gcagtcctac aaagcaggaa ttttctgtta cttttttgga
    31261 aatagtaacg tttatacagc tttgacactt cgtatcaaag cgccaaacac actccgaggg
    31321 atttacagaa agcagaaaag gaatgatctg gtataagatc attccttttc tctctttttc
    31381 tttaagtaat tatatacaat gtacgacgaa gtcgtcattg caatgctgat ccaccaccta
    31441 aagggaactt taaacaacat tgataagata aagaatataa acaacgaaaa tacgttatac
    31501 ccaattaatt ttattgtata tctcatgatt aaaagttaat ccttccgttg ttaggaatgg
    31561 catcattttt atcccataat tgtgctaaat aagtccccgg tgataataaa ttcatagcgg
    31621 attctaaagc aacatcattt acaaaccaac tacctagata tctagaaatt gctgaacgaa
    31681 tagcactttt tgctgcatgt tttcctttta ctttaattag atttgcaagg cctgcagtag
    31741 ttcctcctaa tgctaaagct attgtagtat ctaatagagc acccatttga ttaactgtaa
    31801 taccttgcca agctgctcta aatggagagt atgtaggtgg gattgtataa tcgccttgta
    31861 attgtcggtt aattacttct ttgatccatt gttgtgagac gtctggatga aaagattgga
    31921 tttcgtttgc aagtgtattg atttgttctt ctgttagaga agtgacaggt tgaagttcca
    31981 tatttgtttc aatttgcgat acttgttcag aagcgtatac agctgaaaca cttggaatcg
    32041 ctgatacaat taacacaatt gacgtcaaaa aaaccgaaat aaatttcatt aatttgttca
    32101 tgagcttttc tcctttttat ttgtatctgc ttacatttta ttatatactg ttattatagt
    32161 caagaaaaat atgctattat gttaaaaaaa tatttttcaa aatataaatg gacggattta
    32221 ttttggattt tatttgttat tttgacctgc ctctatattg gtaaccatga tttgtttact
    32281 ctcaatcatc aagaattctc ttttcgtggt agcttttggg gtttggtact ggccttatat
    32341 cacttattgt tcattgataa gtttgtaatt tcgaatcgaa aataaagatt agaactatga
    32401 ttgactggct acttttaata ttgattttgg aggaagattt tgtctctatt atttattatt
    32461 ttaaatttat ctattttgta caatatctat tctttgagac gggagaaatc gaaatacttg
    32521 atttatacgg cctatatcat atttggggta aatgtagtat atggtattca atggttatta
    32581 agagaactga tttcaactat ttccccttaa tgtgtatgga aactataaca aaacgcataa
    32641 gattaaggtt tgtgtacctg ttcttatgcg tttttgtaat attgaagatt ttcggtaagt
    32701 tttatacctt tgggaagtct agtttagaat gctttcccaa ccagaatctc tgcttcgatg
    32761 gtaatctctg tcagttggct ccagtcaatc ttgctctggt caacatgaaa gaggagagga
    32821 gtcatactga gtagggcttg gagttgttct gctgtgatag tcttagtcag agaggcagtt
    32881 tgactagata ggatggtaaa gtgttcctgg aaatgctcct tgatatcttg gttagaatac
    32941 tccttgtttg tcagctggtc ctgtactctt tgacggattt ctttgaggtg attttcagtt
    33001 gggataacct ttatcaagat accgtctttg gataaaacgc gacgaaattc tccatagttg
    33061 gcaggtgaga agatatcaag cagaatatcc atgttagcgt cttttatagg aagtcgtgcc
    33121 aagtcgccaa cgaaccaatt gactgcccag ttgggttcac ttttagcagc gatttggact
    33181 gaatctttgg agatgtcaaa ggcatagaaa gttttttcag agtgactttc ttgtagtttg
    33241 cgagaataga atccttcacc acaaccgata tccaaaattg ttgtggtagt ttttgagctt
    33301 gcaagcaagt cagatacagc atctaagata gcttggtaaa agccggcttc taggatttgt
    33361 tgacggtttt gaaaattttc cttgtcatag ttagcagatt gcttgatttg aggtgctaga
    33421 ttgacatagc caaatttcgc caagtcaaaa gaatgacggt tgcagcactt gaaattagtc
    33481 tctaacagag tcagattttc ttgacagata ggacaggcaa aggcagtcgc agaagcaaaa
    33541 cgctgaagtt tgggcttgag atttgtattc atagtttaag tgtatcaaaa gaggcaaatg
    33601 aaagcaactt taggaataag tagatgggag attcagtaga aataaaacta attctccaat
    33661 ttatagaatg aaattgcttt tatatctaaa ttgctatata ataatgataa ggaggaaata
    33721 agtatgttaa aagaagtatt aaccgttgca aaagttgcga aaaaatcttc attatttttg
    33781 ggtggtgtcg catttggtac ccttggtttg aaaatcttag caagtaagga agctaaaaaa
    33841 ggttattcta aagctttggc taaggcttac aagttgaaag acgagctaga tgcatctgtt
    33901 tctgttgtga agcaacatgg agacgatgtc ttgcaagatg ccaaatattt gtacgagcaa
    33961 gagaaaaaag aagagcaatt agatagcctt ataggtgaat aatatgtctt ttaaagtgct
    34021 acatagagga taccaacata tccgactatc atcttctttt tcacttacct tggatattca
    34081 agactatctt cgttccttgg cgagagatga aaaggggatt gagtctatcc agttttacat
    34141 ggatcaacag cactttactc tacgcataaa agaaggcttt tctgtattag ataatgcaga
    34201 agccttttta aaaagaattg ataaagggaa agtttctgag ttgatgactc ttcccattcg
    34261 tagagaagag agtgcttatt ctattgtttc aggtgcagcg gttaagcgtg tactttttcg
    34321 tagttttgtg ccgtatccta ttcgctatat atggacttgt tatcaggctt tgggttatat
    34381 tagagaagcc tatcaaacac tagcgcgtaa ggaactaacg atggaagtct tggactgttc
    34441 ggctatttta ttgtctttgt ttatgaacca atccaagaca gctagcaata tcatgtttat
    34501 gcttgatttg gggaatcatt tagatcagtg gtccttgaaa aaaactgcaa cagatttaga
    34561 acagagtctt cttgcaaaag agagcgatgt attcctagta cagggcgata cggttgttag
    34621 tatcaagagt tccgatgttc aaataggaga tgtcttgatc ttatctcaag gaaatgaaat
    34681 tctgtttgat ggacaagtag tttcaggttt aggtatggtc aacgaaagtt ccttgacagg
    34741 agagagtttt ccagttgaaa aaagagagtc tgatttggtt tgtgcaaata cagtattaga
    34801 aactggagag ttacgcattc gtgtaacaga taatcagatg aacagccgta ttttacagct
    34861 gattaagttg atgaagaaat ctgaagaaaa caagaaaacg aaacaacgct atttcatcaa
    34921 gatggcggat aaagtcgtta aatataattt cttgggggct gggctgactt acctattgac
    34981 aggttctttt tctaaggcta tttctttcct attggtcgat ttctcctgcg ctttgaaaat
    35041 ctctactcct gtagcttatt tgacagttat caaggaaggg ttgaaccgtg aaatggtgat
    35101 taaggatgga gatgttctgg agaaatatct ggaagttgat actttcttgt ttgataagac
    35161 aggaacaatc acaactagtt atcctatagt tgaaaaggtg ttaccttttg gagactatag
    35221 tgaggaagat attctcagaa tcagtgcctg tcttgaggaa cacatttatc atcctattgc
    35281 taatgccatc gtcaagcaag ctgagataga gggaattgaa catgaggaaa tgcatgggaa
    35341 actccaatat atcgcaagca aggggatcaa atctcatata gatggccaac cagttcttat
    35401 tgggaattat gtcttgatgc aggatgagca gattcatatc agttcagaac aaaatgcttt
    35461 aattgaagag tacaagagtc actacaatct cttattcttg gcttatcaaa atgaattgat
    35521 tggaatgttc tgcattcata ctcctttgag aaaagaagca aaaacagcct tggataaact
    35581 taaggcacag gggaaaaaat tgattctggc aacaggagac accttgatta ggacagagga
    35641 attagtcaaa gatttgccct ttgatcaggt ctatacagac ttgaaacctg atgggaaatt
    35701 tgagttagta gagaaactgc agaaagcagg tcacactatt ttgatggttg gagatggatt
    35761 gaatgactca gcggctttaa ctctatcaga tatcggtgtg gtgatgaatg agagtgcaga
    35821 tatttctaag cagatgagtg atatcttatt gttagataat cgtttggatt tcttccaaga
    35881 gttggattcg ttatcatcat ctttgcaaac actcatcaag aaaaatattc aagataccgt
    35941 tgtcgtaaat agtagtttga ttggctttgg cttatttaat tggctcagtc cttcaaatct
    36001 ctctatctta cataatctaa caaccttgcg cattgtcctg cgtagcctgt ctattaaaaa
    36061 tagatagatg agagttatta acagcaaaaa ggagttacct ttctcgaggt taactccttt
    36121 gtttatagat aaatgttgaa tggtttagta agtcaataca aagtattttt tcttcccacg
    36181 acggataaca gtcagttcat tttctaactt atcagcgtca ctcaagacat agtcaaggtc
    36241 ttggatgcgg tcgccgttta cgtagatggc tccgttttgg acgtcttcac gggcttggcg
    36301 ttttgagtta actataccag atgagacgag cagttccacg atattgttgt tttcgtctgc
    36361 ctgtacttgg tagtttggca caccacgaag tccttgtttg agctctttga cagaaaggtt
    36421 tttgatgttt cctgcaaaga gttgctcagt gatgttaagt gcttctttgt aggcttcttc
    36481 tccgtgaaca agtgtaacaa cttcacgagc caagactttt tgagccaagc gttcgtgtgg
    36541 cgctgcttca aattgtttac gaatatcttc aatctcatca agtgacaaga aagtaaagat
    36601 tttcaagaag cgaacagcgt cagcgtccat cacgttcatc cagaattggt acatttcgta
    36661 tggagaagtc ttttcgggat tgagccagac ggcatttcct tctgatttac caaatttttt
    36721 accagttgca tctgtgatta gtggaacagt gataacgtga ccagtcttgt ccgccttacg
    36781 acgaagcaat tcggtaccag ctgtcatatt tccccactgg tcagaaccac cgatttgaag
    36841 agtgacatta tggtcttggt taaggacgaa gaagtcgtac ccttgcatga tttggtaagc
    36901 gaactcagtg taagaaattc ctgtttcgat ccgtttttta acagattcct tactcatcat
    36961 gtagttgacc gtgaagtatt ttccaatgtc acggaggaag tcaatgaagc tgatgctgcc
    37021 aaaccagtcg tagttgttga ccatgacagc cttgttttcg ccattttcaa agtcaagaaa
    37081 acgagaaagt tgtccttgga tagacttgac ccagccatct actgtgtctt ttgtttggag
    37141 actacgttca gcatctttga aggacggatc tccgatgaga cctgtagcac cgccaacgag
    37201 cgcataaggt ttgtgacctg ctagttgcaa gcgacgactt gtcaagattg cgacaaggtg
    37261 gcctaggtga aggctgtcag cagttggatc gtagccagta taataagaaa cttgaccttc
    37321 ttctagggct ttacgcaaag cttcttcatc agtcgtttga aatatcaaac cacgctcttt
    37381 tagctcatca aaaatgtgca tgtgtctttt ctccttttta aaattattgt ttctacctat
    37441 tgtatcacaa acttgggcaa tagcctagca gaatagggaa gaaagtggct attttattga
    37501 aaatttccct tttgtggtat aatagataga gtgaggaaat ccatgcaaaa tcaattaaat
    37561 gaattaaaac gaaaaatgct ggaatttttc cagcaaaaac aaaaaaataa aaaatcagct
    37621 agacctggca agaaaggttc aagtaccaaa aaatctaaaa ccttagataa gtcagccatt
    37681 ttcccagcta ttttactgag tataaaagcc ttatttaact tactctttgt actcggtttt
    37741 ctaggaggaa tgttgggagt tgggattgct ttggggtacg gagtggcctt atttgacaag
    37801 gttcgggtgc ctcagacaga agaattggtg aatcaggtca aggacatctc ttctatttca
    37861 gagattacct attcggacgg gacggtgatt gcttccatag agagtgattt gttgcgcact
    37921 tctatctcat ctgagcaaat ttcggaaaat ctgaagaagg ctatcattgc gacagaagat
    37981 gaacacttta aagaacataa gggtgtagta cccaaggcgg tgattcgtgc gaccttgggg
    38041 aaatttgtag gtttgggttc ctctagtggg ggttcaacct tgacccagca actaattaaa
    38101 cagcaggttg ttggggatgc gccgaccttg gctcgtaagg cggcagagat tgtggatgct
    38161 cttgccttgg aacgcgccat gaataaagat gagattttaa cgacctatct caatgtggct
    38221 ccctttggcc gaaataataa gggacagaat attgcagggg ctcggcaagc agctgaggga
    38281 attttcggtg tagatgccag tcagttgact gttcctcaag cagcattttt agcaggactc
    38341 ccacagagtc ccattactta ctctccttat gaaaatactg gggagttgaa gagtgatgaa
    38401 gacctagaaa ttggcttaag acgggctaag gcagttcttt acagtatgta tcgtacaggt
    38461 gcattaagca aagacgagta ttctcagtac aaggattatg accttaaaca ggacttttta
    38521 ccatcgggca cggttacagg aatttcacga gactatttat actttacaac tttggcagaa
    38581 gctcaagaac gtatgtatga ctatctagct cagagagaca atgtctccgc taaggagttg
    38641 aaaaatgagg caactcagaa gttttatcga gatttggcag ccaaggaaat tgaaaatggt
    38701 ggttataaga ttactactac catagatcag aaaattcatt ctgccatgca aagtgcggtt
    38761 gctgattatg gctatctttt agacgatgga acaggtcgtg tagaagtagg gaatgtcttg
    38821 atggacaacc aaacaggtgc tattctaggc tttgtaggtg gtcgtaatta tcaagaaaat
    38881 caaaataatc atgcctttga taccaaacgt tcgccagctt ctactaccaa gcccttgctg
    38941 gcctacggta ttgctattga ccagggcttg atgggaagtg aaacgattct atctaactat
    39001 ccaacaaact ttgctaatgg caatccgatt atgtatgcta atagcaaggg aacaggaatg
    39061 atgaccttgg gagaagctct gaactattca tggaatatcc ctgcttactg gacctatcgt
    39121 atgctccgtg aaaagggtgt tgatgtcaag ggttatatgg aaaagatggg ttacgagatt
    39181 cctgagtacg gtattgagag cttgccaatg ggtggtggta ttgaagtcac agttgcccag
    39241 cataccaatg gctatcagac cttagctaat aatggagttt atcatcagaa gcatgtgatt
    39301 tcaaagattg aagcagcaga tggtagagtg gtgtatgagt atcaggataa accggttcaa
    39361 gtctattcaa aagctactgc gacgattatg cagggattgc tacgagaagt tctatcctct
    39421 cgtgtgacaa caaccttcaa gtctaacctg acttctttaa atcctactct ggctaatgca
    39481 gattggattg ggaagactgg tacaaccaac caagacgaaa atatgtggct catgctttcg
    39541 acacctagat taaccctagg tggctggatt gggcatgatg ataatcattc attgtcacgt
    39601 agagcaggtt attctaataa ctctaattac atggctcatc tggtaaatgc gattcagcaa
    39661 gcttccccaa gcatttgggg gaacgagcgc tttgctttag atcctagtgt agtgaaatcg
    39721 gaagtcttga aatcaacagg tcaaaaacca gggaaggttt ctgttgaagg aaaagaagta
    39781 gaggtcacag gttcgactgt taccagctat tgggctaata agtcaggagc gccagcgaca
    39841 agttatcgct ttgctattgg cggaagtgat gcggattatc agaatgcttg gtctagtatt
    39901 gtggggagtc taccaactcc atccagctcc agcagttcaa gtagtagttc tagcgatagc
    39961 agtaactcaa gtactacacg accttcttct tcaagggcga gacgataatt ctctaaatga
    40021 agtggccaat caatggattg ccactttttt cctttcgtgt tacaataagg gtatgaatca
    40081 gtatcagaaa aagattgtta acggaaaaat ttattcgctc ctatccggct taatatgggg
    40141 aatctgtgga attttaggag agtacttctt tactcattat caggtgtctt cgggctggat
    40201 tacctctatg cgtttgacac tggcagggag tcttgtactc atttggtctg caatacaatt
    40261 aaaatcgcaa gtgctagata tttggcgaga caagaaaaat tacctgccct ttttagccta
    40321 tgctattttg gggatttttt cagttcagta ttttttctat ctctgtgtag aatactcaaa
    40381 tgctacgaca gcaactattt tacagtttat tagccctgtt tttatcctct tttacaatcg
    40441 cttggtttat caaaaacgag cgtcaaaaag cgctgttttc tatgttttgg ttgccatgct
    40501 gggtgtttgc ttgatggcga caaagggaga tctctctcag ttatccatga cgccgctagc
    40561 tcttataaca ggtttgctga gtgccatggg tgttatgttt aatgttatct tgccccaacc
    40621 ttttgctaag cgttatggtt ttgttcctac ggttgggtgg gggatgattt tggcaggttt
    40681 gtttagcaat gtcctctcgc cggtttatca gctttccttt actcttgata tttggagtat
    40741 cttgatttgc ctcattatcg ctttctttgg aacggctttt gcttttttca tttccatgaa
    40801 ggctgtgtcc ttggtttctc ctttggtggt tgccgttatc agtgccagtg aacctctctc
    40861 ttctgctctc ttgagtgttt tgttcttagg attagtagtg gattggtccc tccttctagc
    40921 tatagccttg attattttac ccatgatatt tttgtctata gaagaagcga aagaaagtag
    40981 ataaaaagtc ttttcttaat tctaaaagtg tgctatacta gaatagtcaa taaaacacgg
    41041 ggagatagtt gtgaagagtg tttttaggtt gtatcggtag gggcttgctt ttaccgacag
    41101 cacgttttat ctcacatccc taaaaaatca tacctaaaaa cagacaaaaa ggtttcaaat
    41161 ttgaggcctt ttttggtaga ataggtatca ttataacgaa ccaggaggca cctatgactg
    41221 ctacaaaaat gaacgctcaa gaaattatcc aatttatcgc caatgctgaa aagaaaacca
    41281 gtgtcaaagt aacctttgag gggcaactcg caactgctgt gcctagctct gttgtcaaac
    41341 taggaaatgt cctattcgga gactggaagg acgtggctcc gcttcttgaa ggtttggtag
    41401 aaaatcaaga ttatgttgtc gagcaagatg ctcgtaattc tgcagttcct ttgctagata
    41461 agcgtgctat caacgctcgt atcgagccag gtgctattat ccgtgaccag gtggaaattg
    41521 gtgacaatgc tgttatcatg atgggagctg ttatcaatat cggtgctgaa atcggtgctg
    41581 gaaccatgat tgacatgggt gccatccttg gtggccgtgc tatcgttgga aaaaatagcc
    41641 acgttggtgc aggtgcagtt ttggcaggtg tgattgagcc agctagtgct gaaccagtcc
    41701 gtgtcggaga caatgttctt atcggtgcta atgcagtggt tatcgaagga gtccaaatcg
    41761 gtagtggttc agttgtcgct gcaggagcta tcgttaccca agatgtccca gaaaacgtgg
    41821 tagtagcagg tgttccagct cgtatcatca aagaaattga tgcccaaacc caacaaaaaa
    41881 cagcgctaga ggatgcgctt cgtaccttgt aattgtaaaa gtaaaaaaga ggcggaaccc
    41941 tttttccagc ctctttctgc tataacggag gacagataga tgttagattt gattcagact
    42001 agacgagctt tacaccagat tccagagatt ggcttggagg agttcaagac tcaggcttat
    42061 ttgctggatg tgattgagaa attgactacg ggcaaggatt ttgttcaaat tcgtacttgg
    42121 cggacaggga ttttggtcta cctgcaggga agtcagccgg agcgaaccat tggttggcgg
    42181 acagatattg atggtctgcc tatcgtcgaa caaacaggtc taccttttgc ttctcaacac
    42241 caaggtcgca tgcatgcctg tggccatgat tttcatatga ccattgcctt aggctgtctt
    42301 gagcgcgccc ttgaggagca acccaagaat aatctgctct ttctatttca gcctgctgaa
    42361 gaaaatgaag ctggtggcat gctcatgtat gaggacggtg cttttggaga ttggttgcca
    42421 aaccaattct atggtctcca tgttcgtcca gatttgaaag tcggccagat tgcgactaat
    42481 actcatacac tctttgcagg aacttgcgag gtgaagatcc gtttcaaagg caaaggtggc
    42541 cacgcagctt ttcctcatga agccaatgac gccttggtgg cggctagtta ctttgtgacc
    42601 caagtgcagt cagttgttag ccgcaatgtc aacccaatcg agggagcagt ggtgaccttc
    42661 ggcgtttttc aagctggaac caccaacaat gtcatcacag acacagcttt tttacatgga
    42721 actattcgtg ccttgacaca ggacatgagt ctcttggtgc aaaagagggt aaaaacagtt
    42781 gcagaagggg ttgcagctgc ctttgatatg gaagtcgaag tggaactcaa acaaggtgga
    42841 tacctacctg ttgagaacaa tccagccttg gcgcgtgaac tgatggactt ctttgacgaa
    42901 aaagacggaa tcgagttgat tgatatcgaa cctgctatga caggcgagga ctttggttat
    42961 ctcctttcaa aggttgatgg cgtgatgttt tggctaggta tcgatagtcc ctacgctctt
    43021 catcaccctc aaatgagtcc taaggaagaa gtcttagcta ttggggtggc tgcggtgtct
    43081 agtttcctga aaaagaaggc agcagaatag agggcttgtc tatgaaatcg gaattacgca
    43141 agcaagtctt gcatgaaatg aaggctatat ctcaagagca aaaacaggct atagaccaag
    43201 ctttaaccga gcggctttta caccatccct tctaccaaga agccaaggtc atcgcaacct
    43261 acctctcttt ttctcatgag tttcaaacgc gggaactgat tgagcaggcg ctgaaggacg
    43321 gcaagaaggt tttaataccc aaaacttatc ccaaggggcg catggagttt gtggtctatg
    43381 atccgcaaca gttggtaaaa acttcctttg ccttactgga gccacaggga gatgtggaag
    43441 tggtggatgc atctcagatt gatttgattc atgttcctgg tctggctttt acgacgaaag
    43501 gatatcggat aggatacggt ggaggctatt atgaccgcta tctggaacat ttttctggtc
    43561 gtactttgag tacgatatat ccttgtcaaa ttcaggactt tatacctgaa aaccatgata
    43621 ttcctgttca ggaggtatta attgatgaag gaaatctttg atagacgtta ccctgtgacg
    43681 agtttcttcc tcttagtgac ggccttggta tttttactaa tgttggtcac tgcaggcgga
    43741 aactttgaca gggcagatac attatttcga tttggagcca tgtatgggcc agctattcgc
    43801 ctctttcccg agcaggtttg gcgtctcttg tctgccattt ttgttcatat tgggtgggaa
    43861 catttcattg ttaatatgct ttcactttat tatcttggaa ggcaggtaga ggagattttc
    43921 ggttctaagc agtttttctt tctctatctt ttatcaggaa tgatgggcaa tctctttgtt
    43981 tttgtattta gtcctaaatc cttagcagca ggcgcttcta cctctcttta tgggctattt
    44041 gccgcgatta ttgttcttcg ctatgcaact cgcaatcctt atattcaaca gctagggcaa
    44101 tcctatctga cactttttgt ggttaacatt attggaagtg ttctgattcc aggaatcagc
    44161 ctagcaggcc atatcggtgg tgcagttggt ggcgcatttc tagcagttat ctttccagtt
    44221 agaggagaaa aacggatgta taataccagc cagagattag gagcggtagt cttgttcgta
    44281 ggactcgcca ttttgctttt ctacaaggga atgggaatgt gacgaagttg aaagaaaatt
    44341 tgtgtaatga aaaaagataa ggcatttttt gaaccttatc tttttatttt attttattcc
    44401 ttctcagtca attcttttcc aagttggatg aggtaattct tcaaatcatc tttgacttgt
    44461 gggtgtttga gggcgtagtc gatggatgtt ttcatgaagc caaacttgtc tccgacatcg
    44521 taacgagccc cattgaactc acgagcaaat acacgttgtg ttttattgag ggtgtcgatt
    44581 gcatctgtca gctgaatttc atttcctgca cctggagctt ggttttcgag gatttggaaa
    44641 atttcaggcg tgaggaggta gcgtccgata atagcaaggt cgctaggagc gtcctctgga
    44701 gctggttttt caacaaaggt ttcaacactg taaagaccat cttttccttc gccttgcgga
    44761 gcaataaccc cgtaagcaga tacttcgtca tgagggactg gcatgacagc gatagtagac
    44821 gcgtgggtac gctcgtagtc atccatgagt tgtttggtaa gtggaacagc cttttcgtct
    44881 gtgatatcca tcaagtcatc accaagcata acgacaaaag gttcatttcc gacgaaagcc
    44941 ttagcttgca aaacagcatc tccgagaccg cgtggatgag tttggcggat aaaatgcaga
    45001 cgcatgtcag ttgttttatc aactagcttc aaaagatctg ttttcccttt ttctttgagg
    45061 ttatattcca attcgaagtt tgaatcaaag tggtcctcaa tagaacgttt tgatttacca
    45121 gtgacaacta gaatatcttc aatacctgat ttgagagctt cttccacgat aaactggata
    45181 gttggtttgt ctacgattgg caacatttct ttggcaaggg ccttggttgc tggtaaaaat
    45241 cgagttccta gtccagcagc agggatgact gcctttctaa cttttgatgt cataaaaatc
    45301 ctttctatag agggttaaga ccactcattt tctgctttaa attcattgtt catgatgtca
    45361 taaatggcat ctttgatatt ggttccgtga taaataactt ggtaaatagc ctgtgtaatg
    45421 ggcatataga ctccaagttc ttgggctagt tcataggctg ctcgagtcgt tgaaattcct
    45481 tcgattacca tgcccatatt agcttctata tcagctaggg attctcctcg tccgagagca
    45541 tctccagctc tccagttacg agagtggatg gaagttcccg ttacgatcaa atctcccaca
    45601 ccagataagc cgctataggt caatggactg gccccgagtg ctacccctag gcgggtgatt
    45661 tctgctaaac ctcgagcgat gatggctgcc ttagcattat caccaaatcc aagaccatgt
    45721 aaagctccag caccgacagc aataatattt ttaagagcac cagcagtttc aaccccgata
    45781 acatccgtat tggtataaag tcggaagtag tgattactaa atagcttctg aacgtattga
    45841 gctgtttgta aatctttaga agcagcagtt attaaagtta ggtcacgcac aatggtctct
    45901 tctgcatgac taggccctga aacaacgacg atatcactac ggagatgttc aggaatttct
    45961 tcttcaagaa tggttgataa tcgtttatgg ctatcaggtt ctaatccctt tgatgcgtgc
    46021 atgatgataa ccttatggtc caaggtttgt gcaacttgct gggcaacaag tcgtgtcact
    46081 tttgttggga caacaaacaa aatcgcatcc acatctttca atgtttctgc taagtcggtg
    46141 taggcaatga tattttcgtc tagaacgaca tctttaaagt agtgcttatt agtatggtgt
    46201 gtattaattt cattgatttg ctcgggaaga tttccccaaa tacgtacctc gtgtccattg
    46261 tcatttaaga cttgtgaaag ggcggttccc caagaaccag gccccaagac ggcgacggtt
    46321 tgtttttcca tgatttcctc cttgatagag ttctttctct tattctatca tattctaggg
    46381 gattttgcac ttgcattact ggggtatggt ggaaaaatac acaaaaaccg agacgaaggg
    46441 ataaactctt agtctttagt taaagtgaga agaaatctga tagatagttt gattcagtat
    46501 atgcttataa tagaggtaaa caactcagga agttcttgta ggttgcgaga gtttggctaa
    46561 aaaaatcagt cgttcagaat tttgtggtga tgagtctgaa ttaagtatcc gtcaattaat
    46621 tagaattgaa aatggagaat ccagaccaac actaacaaag ttaaaatata tcgctgaacg
    46681 tttgggggtt gaagattaca agttgatgcc aagttatata gagttggata aggaatacct
    46741 agaattgaag tatttcttga tgaggactcc tacatacgaa gatgaaacta tcgcccaaaa
    46801 gaaagagagt gttttgataa gatttttgaa gagtattatg ataggctacc tgaggaagaa
    46861 agatttatca tcccaaatta ttcatatctg gcactaacga actacacagt tcaaaaatta
    46921 ccagaaaagc tagttgaaat actgtccttc tggtgatttt gcttaatttc tgatgttcga
    46981 gacataattg aggagatttg tcttgatttt ttcctaaaaa agggcagact cctcccttgg
    47041 tttgatgctc gatttttaaa ataaggtgac ttattctgtt aggcatgttt tcccctgccc
    47101 tctagctcta tatggaacag ggagtatcag atttatctgg cagattgtat caaataaggc
    47161 ttgaaactgt tttgaatagg catatagact tgagaatttg agaatatgtc gtctagcagt
    47221 agagacatat tttccggcaa tatgaaggaa gagacgtcga aaacgcttga tagtcaaggc
    47281 ctttacttca tcaccagcta gctgctttaa aaagaggtag agattataag ccagacagcc
    47341 catcatcata cgtacttcat tcttaatcat ggtcgaacta tctgtcttat ccccaaagaa
    47401 tcctgctttc ctttctttga taaagttttc agcattccct cgttcacgat agaattgaaa
    47461 cagctcctca ctatctacac tgcttaaatt gttcaaatga acttttttac aaccataaaa
    47521 aagagcactt aatcgtactc ttctctttta aggattagtt gaattaattc aaatccacca
    47581 gttctcctgt ttctaggtag actaggcgtt cacaaatgtt agcaatgtaa tcagcgaagc
    47641 gttccagatg ccctatgata taaaggtatt gagttccatt gggaattgag gtttcttggt
    47701 ctttcataag tccaatgatt tcctttgata aggcataata atattggtca atctgttcat
    47761 ctttttgagc aatactaata gcttttgagg cttggtgcaa aggaaaggca accaataaat
    47821 cggctagcat gctgagggat aatttaccca tttggtgtaa ctgttcttcg tcaggggcta
    47881 gttgattttc ttttagttgc aaaacagctt tagcaatgcc tgccatatgg tctcccatac
    47941 gttcaaggtc tgaacaagaa gacatgatgc taatcacaaa tcgaaggtca gacacttgtg
    48001 gctgctgcaa ggccaacaaa cgggcacagg tcaattcgat agcgctttga ccttggttga
    48061 tagcatgatc cttattgata attagctctg ccatctcctt gtctttggag gctaaggcca
    48121 gtaaggcttt tgaagctgtt tcaaggacaa gttgccctag tcctaaaaag gattgttcta
    48181 attcatgcaa ttctaagtca aattgatttc tcataggttt ttccttcctt atccgaaccg
    48241 tcctgaaata tagtcttctg tgcgctgatc ttttggattg gtaaacacgt caacggtatc
    48301 tccaaattcg caaatttctc ctgttaagaa aaaagcagtt ttatctgaaa tacgtgaagc
    48361 ttgttgcatg ttatgggtaa caatgataat cgtataatcc ttttttagtt gctgaatgag
    48421 gtcttcaatt tttaaagtgg agatagggtc taaggctgaa gtcggctcat ccattaacag
    48481 aatatcaggt tctactgcta aagctcgcgc aatgcaaagg cgttgctgct gaccgccaga
    48541 taaggacatg gcactctttt taagatcatc tttgacttct tcccaaatgg ctgccccttt
    48601 taaagatttc tccactaagg catctaattg ttttttgtct cgaataccat gtgtccttgg
    48661 gccataagcc acgttatcat agatagacat ggcaaaggga ttaggctgtt gaaaaaccat
    48721 ccctacacgc ttacgtagct gattaaggtt gaatttgcta ctataaatat cttgctcatc
    48781 taagaggact tggccttcaa tatggcaaga aggaaccaaa tcgttcatcc ggttaagggt
    48841 ttttagaaaa gttgatttgc cacaaccaga tgggcctatc aaggcagtaa tctgtctttc
    48901 tggtaattga atcgaaatat tttttaaggc ttgaaaatcc ccgtaaaata agtctaggtg
    48961 tctgactgaa aatgttccca tactaggaag ctcctttcac aagttttcga gataataagc
    49021 ttgatagagt atttatcatt aaaacagtaa taatcaaaat cacaccggta gcataggctt
    49081 cattgacatg tagcccctca cttgacagca tatacatatg cagggctaga gaacgacctg
    49141 aagacatgag actacttggc gtattggtag aggtacctaa tgtatacatg agggcagctg
    49201 tttcaccaac gatacggcca atagctagta tcactccagc taaaatacct ggcatggcaa
    49261 ctggtagaac aattctaaaa acagtccgta acttacctgc cccaagtcca taacttgctt
    49321 gacgcatgct atcactaaca gataaaaggg cttcttctgt tgagcgaata atgactggca
    49381 acaccatgat aactgaggtt aagattcctg ataacagaga gtattgaaaa cctaagaaga
    49441 ctacaaagaa gagcatgcca aacagaccaa aaacaatgga aggaatccca gacaaggtat
    49501 ctgaggccaa tcgcatgatt ttaacacaaa gggaatcttt ttttgtatat tccacaagat
    49561 aaaaaccagc aaaaatccct atgggcaagg ctaaaagaag agcaccaaag accagaataa
    49621 cggtggaaat aatcgctggc ataagggaaa tgttctcaga agtataagtc caagaaaaga
    49681 gggatagact tagatgaggt aagcctttga tgaggataaa accaatgatt aaaaagagag
    49741 agccaaaggt taaagctgaa aaacaataaa cgagaagttt tagcaggtat ttactcataa
    49801 gatgattttc ctttcaagta ggcaaagtag gcattaatca agagaataag gaaaaagaga
    49861 actgctgagg ttgcaataag ggcttcccta tgctgacctg atgcgtaagc catctccaga
    49921 acaatattgg ttgttaaggt tctggttcct gaaaagagtc cacttggaat aattggctgg
    49981 ttgcctgcca ccaaaataac tgccatggtt tcacctactg cgcgaccgat tcctaaaata
    50041 actgctgata aaataccaga tctcgcagct ggcaagatga cactaaaaat actccgttca
    50101 tgactagctc ctagagccaa gctaccagaa taatacgttt tgggaactgt tcggatagca
    50161 gattctgaca aactgataat ggttggcaaa atcattattc ctaatagtaa cgaagcggtt
    50221 aggacactca tgccatttcc taaaaagctt ctaatccaag gcaccaataa ttgtaggccg
    50281 aaaaaaccat aaacaataga tggaatggct gccatcaagt tgatagctga ttttaagaag
    50341 ccatagacgg gctttggaca ataataaacc ataaacaccg atgtcaagat gcctgttggc
    50401 accccaatca caatcgctcc taaggtaatt aataaggaac caacgatcat tggtaaaata
    50461 ccatagcttg ccggaatgtt cgttggcgac caatcactgc ctaataaaaa acgggcaaag
    50521 ccgtagttag ctatgaaagg taagccatta ctaaaaataa agaaacagat tagcaaaata
    50581 gctacaacag ctactgttgc actcatgaaa aaaattgccc taaaaactgc ttctttgaag
    50641 gcttgttttg tcacatcttg tcctttctag tgaagaaagt aagggagata cgacacctcc
    50701 ctacttgcct tctttatctt attgtacgat gaaacgtctg catctcttta gagatttatg
    50761 gagcaaacat tttatttaat cttgtcccag gtggttaatt tgccactaaa aacgtctgca
    50821 agttcagcca tactgacttg gcttgcctta ttgtcattat tgaccacaac agcaataccg
    50881 tctaaagcaa tagcatcatg ggtgagactc ttaccttctt caggagttaa ttccctagaa
    50941 accataccaa tatcagcggt tttctcctta acagcggtaa tacctgctga agacccatta
    51001 gaggtaatat caatcgtaac ttctggattt tcttttttat aagcttctgc taatttttcc
    51061 attaaagaag atactgaagt ggaacctaca acagacaact tgcctgataa gtgttggctt
    51121 gtatattctg tggtttcggt tttagcttca ataaatttat tatctgtgac cacttgttga
    51181 ccttgtttgg agtggataaa gctgataaaa tcttgaccta gcttggaaag attagaagac
    51241 caaacaatgt tgaagggacg ttgaagaggg tatttaccat ctaaaactgt gtctcgacta
    51301 gccttgacac catcaatctc taaagctttg acagatttcg ttaaagatcc caaggagatg
    51361 tagccgatag cattagcatt cccttgaact gctgagagaa caccttctgt actattttga
    51421 atcacagctg ttttggcagt gttgtcaatt tttttatcac cgtctttttt gagaatccct
    51481 gtgatttctg tgaaggcacc ccgtgttcca gagccatttt ctcgtgaaat cacctcaatc
    51541 gttcctgaag ctgactgttt ggaagcagct gactgattgc cacaggcaac aagcccaaat
    51601 cctgataagc caatggctgc aagagtaagc atttttttga atttcataat aatcaccttt
    51661 atctctatgt atttttcttg tgtaggctta ctacatttat agtctaacaa gtctttgtaa
    51721 aggtttatcc ctgattcatg taaagattgt gtaaagaatc aaaaaaagcc acttttgaaa
    51781 aatggctgct cctaaaaata gctttaaaaa ttattagtcc tgtgcgaaag attggttagg
    51841 aagaaaaatc gtgaagcaac tgcctctgcc aagctgactc gtcaccgtga cttggccacc
    51901 taataattga ctgagttctt tgacaatggc aaggccaaga ccagtgccac cagtttgtct
    51961 gcttcgacct ttattaactc ggtaaaaacg ttcaaaaata cgatcctgct ctaattgact
    52021 aataccaatc cctgtatctg atacagaaat cttaatgcct tcgttcacct tttgggtctt
    52081 gacctcaatt tttccccctt gttcagtgta acggatggca ttggataaaa gattgagtaa
    52141 gatttgggaa agtaattgac tatctgatac gagggtgaca tcatctggca cctgcacctt
    52201 tagctgtaaa tccttcttct tgagctgagg ttgcaagctt tgagtcaaat cctgtacaaa
    52261 ttctgccaaa gaaagggtcg tccattgtat aggcatttgt tgagccttag ataaggtaag
    52321 aagatgctca acaatatgct caagacgcaa gctttctttg taaataatgt ctagaaagtc
    52381 atccttgagc gcttcttctt cagctgacat ccccttaatg gtttcagcaa agcccttaat
    52441 cgaagtaact ggtgtcctca attcatggga ggcatttgag acaaaggcta aatttaactt
    52501 ttcataagtt ctaatcgttg ttaaatcata tagcaagacg agcacagctt ccacagattg
    52561 ggtggggcta aaaacgggaa ctgctgtcac ttctaaaatc aagtcaccct catgaaaccc
    52621 acttacttct tgttttaacc ttgttttttg atcaaaggct tggtgaacta aatttcgaat
    52681 atccatccgt ttgaggtcat caagtgaact tatgtcgccg tccacatcgg gaaaataatg
    52741 aggcagagag cgactggata ataacatctg accttgagcg gaaactaaaa acgtccccat
    52801 ggttaggtgc gacagaagaa cctccattgt ttcggctagg tccttgtatt gctgatcctg
    52861 ttgggagact ttggttttta gggcagacac atactgagcc aaagacttta agtcttcttg
    52921 ccctttttct aaaaagtatt cactactggt caagagaggt tggtgcaagg tctcaaaagc
    52981 aacttcccat ttccaaaggc aaaagagcca gtagccacct tgtcccaaag aaagggctag
    53041 aagaaagaga ccgatgcctt tactgatcca agttaatacc atccctgcaa tcagaatgag
    53101 gctaacactt agattgacta gccaaaattg aaggtagcgt ttcatctata actccttgaa
    53161 cttataacca taaccccgaa tggttcgaat aaattgaggg gctttaggat tgtcttcaat
    53221 tttttccctc aacttaccaa tatgaacgtc caccaaacgt gtttcctgcc caaagtcata
    53281 cccccagata cgttccaaaa gacgctctct agtcagtgtc atgttgggat gtttcataag
    53341 atagagcaag agttcaaatt cttttggggt caaactcagt aacttattcg ccttgtagac
    53401 ttcatgacgc tcagggtata ctttcaaggt cccaaatagc caagaatcgt cagcgatatt
    53461 atctgaatca tctccttctt gttctccttt agttcgcctg aggacagcct tgacacgcgc
    53521 cagcaattct ctagggctaa aaggtttggt caggtagtca tcagccccta attccaaggc
    53581 caaaacctta tcaaattcat cacttttcgc agaaaccatc ataattggag ttttgacgcc
    53641 tttggctctc agccgcttac aaacttccat gccatctaat tgtggtaaca tgatatcaag
    53701 caagataaaa tcaaagggtt ctgtttctgc caaagctaag gccttccgtc catttgttac
    53761 caattgagta gaaaagcctt ccttacttaa atggtagtca agcaatttca gaatgtgttc
    53821 ttcatcatcc actaataaga cttgttttgt catctattat ctcctattgg taacattata
    53881 acacaattat cagaaatcct aacattgcta aatcagatta aatttgctta tcaagactag
    53941 tatctggtca aacgctcaat catctccttg tgctctggat aggtcgccag tagatctacc
    54001 ctttcaaata attcaaaatc ctcaaattca aaaccaggag caacaagaca agaaaccaga
    54061 gcatcatcct tatcaactgt tgatccccaa atagtgccct taggaacaca gtagtgaagt
    54121 tgttgccctt tggatatgtc caggcctaaa gtgactgctt cgtagtgacc atctgctgta
    54181 atcatgtgaa cagtaagtgg ggattctgca tgaaaatacc agatttcatc tgctgtcaat
    54241 cggtgaaaat gtgaaggatt cgtttcttct taataagaaa taaatactgg tataaagcgc
    54301 ccttccctta ccagcaaggt ttatagtgtc tgaagctttt tttgtttgtc taaaatagcc
    54361 accttcaaca tggggagcta actctagagt tcttatcaag tcttctttat ccgtcggagc
    54421 caatgggttg aagtaactct tgttcaaagt ggtgttacga tttcaagaac tcctctcagt
    54481 tctgaggaca cggtaatgat tgatgcgacg gaagtacaaa tcaatcgccc taaaaaaaga
    54541 attagcgaat cattctggta aaaagaaatt tcacgctatg aaggctcaag cgattgtcac
    54601 aagtcaaggg agaattgttt ctttggatat cgctgtgaac tatagtcatg atatgaagtt
    54661 gttcaaaatg agtcgcagaa atatcggaca agctggtaaa atcttggctg acagtggtta
    54721 tcaagggctc atgaagatat atcctcaagc acaaattcca cgtaaatcca gcaaactcaa
    54781 gccgctaaca gttgaagata aagcctgtaa ccatgcgcta tctaaggaga gaagcaaggt
    54841 tgagaacatc tttgccaaag taaaaacgtt taaaatgttt tcaacaacct atcgaaatca
    54901 tcgtaaacgc ttcggattac gaatgaattt gattgctggt attatcaatc atgaactagg
    54961 attctagttt tgcaggaagt ctattatttg gttaggtgaa ttagtgaagc gtttaggcaa
    55021 gtgtctctgg ttacgacgtc atggcctcta aatcgattat atttaggggt catgactagt
    55081 gaagcagtta gctagttcgc atataagcgg ctagcgtcta acaattagga actttagttc
    55141 caataacttt aagattacga cgttttagga cataaatcga tcatatttat gtcctaaaac
    55201 tagtgaagcg cctagccaaa gtccgaatag gatttggcgt tagttactta gattgctttg
    55261 caatcaagta actttggcga tttacatctt ctctggtgct tctactccaa gcaagcgaag
    55321 ggcttctttg agaacgactg cggttgcgta gctgagggct agacggctgt cgcgttctgg
    55381 gctttcatcc aagatacgtg tatgtgcata gtatttgtta aaggattgag ccaggctaat
    55441 tgcaaattta gcaatgatag aaggttcaaa gttatctgcc gcacggttga taatacgtgg
    55501 gaagtcttga atgagtttaa tgatttccca gctttcagta tcattcaagc tatagttgcc
    55561 agctgtttct ggtttgaaat cggctttgcg taagatagat tggatacgag cgtaggcata
    55621 ttgaacgtaa ggtccagttt caccctcgaa ggataccata gcttctaggt cgaagtcgta
    55681 tccatttgta cggtcagttt tgaggtcata gaatttaatg gctccaaccc caacagcatg
    55741 tgctacttgg tctttgtttt ctagttcagg atttttagcc tcgatttgga ccttggcacg
    55801 gctaacagcc tctgcaacag taggctctag caagatgaca ttccctttac gagtagagag
    55861 cttcttccct tcttttgtaa ccagaccaaa aggaacgtgg gtaatgtcgt cactccaatc
    55921 gtagcccatc tcttgcaaga cagctttgag ttgtttaaag tgggcagatt gctcttgacc
    55981 aacgacgtag atagatttag caaattggta ttcattttta cggtagaggg ctgcagccaa
    56041 gtcacgtgtg atatagagag ttgcaccatc agacttcttg atgagggctg gatgttcaat
    56101 tccatatttc tcaagattca caacttgggc accttctgat tcaagaagta gtcctttttc
    56161 agaaagaatg tctacaactg catccatctt atcattgtag aaggcttctc cgttatagct
    56221 gtcaaattca accttcaatt cattgtaaag gcggttaaat tccactaaac tttcatcgcg
    56281 gaaccattgc caaagagcga gagcttcctc atctccattt tcaagtttac ggaaccattc
    56341 gcgcgcttct tcatccaagc tagggtcatt ttcagcttca gcgttgatgc ggacatagag
    56401 tttaaggagt tcatcgattg gatgagcttt tacagcttct tcgtcgcccc attttttata
    56461 ggcaacaatc aacatcccaa attgtttacc ccagtctccc aaatggttga ccttgaccgt
    56521 ttgataaccg attttttgga aaatatgtga caagctatct ccgataacag ttgaacgcag
    56581 gtggccaata gaaaatggtt tagcgatatt cggactagac atgtcgataa caacattttc
    56641 ttgtttacca atattttggt cagcatagtg ttctttttca gtggtaacag cttgcaatac
    56701 ttgagcagaa atggcagatt tatcaaggaa aaagttaacg taaggtcctg ttgcgacaac
    56761 tttttcaaag gcttggctgt tcattttttc agccagttca gccgcaatca tttgtggtgc
    56821 tttacgttcg acttttgcaa gagaaaaagc agggaaagca atgtctccca tttctgagtt
    56881 tttaggggtt tccagtaact ttaaaacagc ctcttggtcc aggctatcaa tgatgctaga
    56941 taattcgcta gcaatcaatt cttttgtatt cattaagagc tcctttttgg acttttctac
    57001 tattttatca caattttaaa gaaagaagaa aaaatttttg aaatctcctg tttttttggt
    57061 ataatatggt tataaatata gttataaata tgcacgcaag aggattttat gagaaaaaga
    57121 gatcgtcatc agttaataaa aaaaatgatt actgaggaga aattaagtac acaaaaagaa
    57181 attcaagatc ggttggaggc gcacaatgtt tgtgtgacgc agacaacctt gtctcgtgat
    57241 ttgcgcgaaa tcggcttgac caaggtcaag aaaaatgata tggtgtatta tgtactagta
    57301 aatgagacag aaaagattga tttggtggaa tttttgtctc atcatttaga aggtgttgca
    57361 agagcagagt ttaccttggt gcttcatacc aaattgggag aagcctctgt tttggcaaat
    57421 attgtagatg taaacaagga tgaatggatt ttaggaacag ttgctggtgc caatacctta
    57481 ttggttattt gtcgagatca gcacgttgcc aaactcatgg aagatcgttt gctagatttg
    57541 atgaaagata agtaaggtct tgggagttgc tctcaagact tatttttgaa aaggagagac
    57601 agaaaatggc gatagaaaag ctatcacccg gcatgcaaca gtatgtggat attaaaaagc
    57661 aatatccaga tgcttttttg ctctttcgga tgggtgattt ttatgaatta ttttatgagg
    57721 atgcggtcaa tgctgcgcag attctggaaa tttccttaac gagtcgcaac aagaatgccg
    57781 acaatccgat ccctatggcg ggtgttccct atcattctgc ccaacagtat atcgatgtct
    57841 tgattgagca gggttataag gtggctatcg cagagcagat ggaagatcct aaacaagcag
    57901 ttggggttgt taaacgagag gttgttcagg tcattacgcc agggacagtg gtcgatagca
    57961 gtaagccgga cagtcagaat aattttttgg tttccataga ctgcgaaggc aatcaatttg
    58021 gcctagctta tatggatttg gtgacgggtg acttttatgt gacaggtctt ttggatttca
    58081 cgctggtttg tggggaaatc cgtaacctca aggctcgaga agtggtgttg ggttatgact
    58141 tgtctgagga agaagaacaa atcctcagcc gccagatgaa tctggtactc tcttatgaaa
    58201 aagaaagctt tgaagacctt catttattgg atttgcgatt ggcaacggtg gagcaaacgg
    58261 catctagtaa gctgctccag tatgttcatc ggactcagat gagggaattg aaccacctca
    58321 aacctgttat ccgctacgaa attaaggatt tcttgcagat ggattatgcg accaaggcta
    58381 gtctggattt ggttgagaat gctcgctcag gtaagaaaca aggcagtctt ttctggcttt
    58441 tggatgaaac caaaacggct atggggatgc gtctcttgcg ttcttggatt catcgcccct
    58501 tgattgataa ggaacgaatc gtccaacgtc aagaagtagt gcaggtcttt ctcgaccatt
    58561 tctttgagcg tagtgacttg acagacagtc tcaagggtgt ttatgacatt gagcgcttgg
    58621 ctagtcgtgt ttcttttggc aaaaccaatc caaaggatct cttgcagttg gcgactacct
    58681 tgtctagtgt gccacggatt cgtgcgattt tagaagggat ggagcaacct actctagcct
    58741 atctcatcgc acaactggat gcaatccctg agttggagag tttgattagc gcagcgattg
    58801 ctcctgaagc tcctcatgtg attacagatg ggggaattat ccggactgga tttgatgaga
    58861 ctttagacaa gtatcgttgc gttctcagag aagggactag ctggattgct gagattgagg
    58921 ctaaggagcg agaaaactct ggtatcagca cgctcaagat tgactacaat aaaaaggatg
    58981 gctactattt tcatgtgacc aattcgcaac taggaaatgt gccagcccac tttttccgca
    59041 aggcgacgct gaaaaactca gaacgctttg gaaccgaaga attagcccgt atcgagggag
    59101 atatgcttga ggcgcgtgag aagtcagcca acctcgaata cgaaatattt atgcgcattc
    59161 gtgaagaggt cggcaagtac atccagcgtt tacaagctct agcccaagga attgcgacgg
    59221 ttgatgtctt acagagtctg gcggttgtgg ctgaaaccca gcatttgatt cgacctgagt
    59281 ttggtgacga ttcacaaatt gatatccgga aagggcgcca tgctgtcgtt gaaaaggtta
    59341 tgggggctca gacctatatt ccaaatacga ttcagatggc agaagatacc agtattcaac
    59401 tggttacagg gccaaacatg agtgggaagt ctacctatat gcgtcagtta gccatgacgg
    59461 cggttatggc ccagctgggt tcctatgttc ctgctgaaag cgcccattta ccgatttttg
    59521 atgcgatttt tacccgtatc ggagcagcag atgacttggt ttcgggtcag tcaaccttta
    59581 tggtggagat gatggaggcc aataatgcca tttcgcatgc gaccaagaac tctctcattc
    59641 tctttgatga attgggacgt ggaactgcaa cttatgacgg gatggctctt gctcagtcca
    59701 tcatcgaata tatccatgag cacatcggag ctaagaccct ctttgcgacc cactaccatg
    59761 agttgactag tctggagtct agtttacaac acttggtcaa tgtccacgtg gcaactttgg
    59821 agcaggatgg gcaggtcacc ttccttcaca agattgaacc gggaccagct gataaatcct
    59881 acggtatcca tgttgccaag attgctggct tgccagcaga ccttttagca agggcggata
    59941 agattttgac tcagctagag aatcaaggaa cagagagtcc tcctcccatg agacaaacta
    60001 gtgctgtcac tgaacagatt tcactctttg atagggcaga agagcatcct atcctagcag
    60061 aattagctaa actggatgtg tataatatga cacctatgca ggttatgaat gtcttagtag
    60121 agttaaaaca gaaactataa aaccaagact cactagttaa tctagctgta tcaaggagac
    60181 ttctttgaca attctccact tttttgctag aataacatca cacaaacaga atgaaaagga
    60241 gctgacgcat tgtcgctccc ttttgtctat tttttaagga gaaagtatgc tgattcagaa
    60301 aataaaaacc tacaagtggc aggccttggc ttcgctcctg atgacaggct tgatggttgc
    60361 tagttcactt ctgcaaccgc gttatctgca ggaagtatta gacgccctcc ttactgggaa
    60421 atatgaagct atttatagta tcggggcttg gttgattggt gtggccgtag tcggtctagt
    60481 tgctggtgga ctcaatgttg tcctcgcagc ctatattgcc caaggagttt catccgacct
    60541 tcgggaggat gccttccgta aaattcaaac cttttcttat gctgatattg aacaatttaa
    60601 tgcgggaaat ctagtcgttc gaatgacaaa tgatatcaac cagattcaga acgttgtcat
    60661 gatgaccttc caaattcttt tcagacttcc cctcttgttc atcggttcgt ttatcctagc
    60721 ggttcaaacc ttaccttctc tgtggtgggt gattgttctc atggtagtct tgatttttgg
    60781 tttgactgct gtcatgatgg gaatgatggg gcctcgtttt gccaagtttc aaacccttct
    60841 tgagcgcatc aatgccattg ccaaggaaaa tttacgtggc gttcgtgtgg tcaagtcctt
    60901 tgtccaagaa aaagagcaat ttgctaagtt tacagaggtc tcagacgagc tttttggtca
    60961 aaacctttac attggttatg ccttttcagt agtggaaccc tttatgatgt tggttggtta
    61021 cggggcggtc ttcctctcta tttggctggt cgcgggaatg gttcagtcgg atccgtctgt
    61081 tgttggttcc atcgcttctt ttgttaatta cctaagccag attatcttta ccattgttat
    61141 ggttggattt ttgggaaatt ctgtcagccg tgccatgatt tccatgcgtc gtattcgaga
    61201 aattcttgac gcagagccag ctatgacctt caaggatatc ccagatgaag agttggttgg
    61261 aagccttagc tttgaaaatg tgacctttac ctatccaatg gacaaggaac cgatgctgaa
    61321 agatgtgagc tttactattg aacctggtca aatggttggt gtagttggag cgactggtgc
    61381 aggaaagtca accttggctc aattgattcc acgtctcttt gatccacaga acggggccat
    61441 taaaatcggt ggcaaggata ttcgagaagt gagtgaagga accctgcgta aaacagtttc
    61501 catcgttctc caacgtgcca ttctttttag tggaacgatt gcagataact tgagacaggg
    61561 gaagggaaat gctactctat ttgaaatgga gcgcgcagcc aatattgccc aggctagtga
    61621 attcattcat cgtatggaga aaacctttga aagtccagtt gaagaacggg gaaccaattt
    61681 ctctggtgga caaaaacaaa ggatgtcgat tgcgcgtggg attgtcagca atccacgtat
    61741 tctgattttt gatgattcga cctcagcctt ggatgccaaa tcagagcgct tggtgcaaga
    61801 agctttgaat aaggacttga aggggacgac aaccattatt attgctcaaa aaattagctc
    61861 ggttgtccat gcagacaaga tcttggttct aaatcaagga cgattgattg gtcaaggtac
    61921 gcatgcagac ttggttgcca acaatgccgt ttaccgtgaa atctatgaaa cacagaaatg
    61981 aaagacaaac tataagaaaa gtcaatagtt ttatctaaac tatttcttat ttcaatttga
    62041 tgatttggcg atgattttag agcacggcaa aaggcccttg aaaaagtcca ttttttcaaa
    62101 ggtaatcctg tgttaatttc agaaattaca tcactttttg ttcgtcaaat ggcagctctt
    62161 tttttaggat ataaaacagg gttcggataa gtttttttgc aaggtggatg atggctacat
    62221 tgtaatgttt tccttgttct aatttagtct taagataggc cttaaaagca ggcgaaaagc
    62281 gagggcatgc tttggcagct tgtatgagta cctaccgcag atgaggggaa ctccgtttga
    62341 ccattcttcc tgctaaatca atctgatctg actgataaat agaagaatcc agtccagcga
    62401 aagcttgtaa ttgagcagga ttatcaaagg catgaatatt tcgaatctca gctaaaatga
    62461 ccgcccctaa acgatcccca atcccagtaa ccgtcgtgat gaccgagttg aactcagcca
    62521 tcaagtcatt gacacatgtt tccgccttgt caatgagccc cttgtaatgt ttgatgtttt
    62581 cattacacga gataaaacgt ctatgcgtta tcaaactcat taccaattaa aacaaaaagc
    62641 tgtggttaga tcctttcgga aattgtcaag cgattggagg aaatgaacta atccacagcg
    62701 gcttattcca agtataccac ttgggctttg gcagtagcta actgcgctaa atataatata
    62761 aggaggagta aaatgaagac agttcaattt ttttggcatt attttaaggt ctacaagttc
    62821 tcatttgtag ttgtcatcct gatgattgtt ctggcgactt ttgcccaagc cctctttcca
    62881 gtcttttctg gacaagcggt gacgcagcta gccaatttag ttcaagctca tcaaaatggc
    62941 aatccagaac ttgtatggca aagcctatca ggaatcatgg tcaatcttgg cctgctggtt
    63001 ttggttctat ttatctctag tgtaatatac atgtgtctca tgacgcgcgt gattgcagaa
    63061 tcgaccaacg agatgcgcaa aggtctcttt ggtaagcttg ctcagttgac ggtttctttc
    63121 tttgaccgtc gacaagatgg cgatatcctg tctcatttta ccagtgattt ggataatatc
    63181 ctccaagcct ttaacgaaag cttgattcag gtcatgagca atattgtttt atacattggt
    63241 ctgattcttg tcatgttttc gagaaatgtg acgctggctc tcatcaccat tgccagcacc
    63301 ccattggctt tccttatgct gattttcatc gtgaaaatgg cacgcaaata caccaacctc
    63361 cagcagaaag aggtagggaa gctcaacgcc tatatggatg agagcatttc aggccaaaaa
    63421 gccgtgattg tgcaaggaat tcaagaggat atgatggcag gatttcttga acaaaatgag
    63481 cgcgtgcgca aggcaacctt taaaggaaga atgttctcag gaattctttt ccctatcatg
    63541 aatgggatga gcctgattaa tacagccatc gtcatctttg ctggttcggc tgtacttttg
    63601 aatgataagt ctattgaaac aagtacagcc ctaggtttga ttgttatgtt tgcacaattt
    63661 tcacagcagt actaccagcc tattatccaa gttgcagcga gttggggaag ccttcagttg
    63721 gcctttactg gagctgaacg aattcaggaa atgtttgatg cagaggagga aatccgacct
    63781 gaaaaggctc caaccttcac taagttgcaa gaaagtgttg aaatcagtca tatcgatttt
    63841 tcatacttgc ctgataaacc tattttgaaa gatgtcagca tttctgcccc taaaggccag
    63901 atgacagcag ttgttgggcc gacaggttca ggaaaaacga ctattatgaa cctcatcaat
    63961 cgcttttatg atgttgatgc tggtggtatt tattttgatg gtaaagacat tcgtggctat
    64021 gacttagata gtcttagaag caaggtggga attgtattgc aagattcggt cttgtttagc
    64081 ggaacgattc gagacaatat ccgatttggt gtgccagatg ctagtcagga aatggttgag
    64141 gtagcagcaa aagcaaccca cattcacgac tatatcgaaa gtttgcctga taagtacgat
    64201 actcttattg atgatgacca gagcatcttt tcaacagggc agaagcaatt gatttcaatc
    64261 gctcgaaccc tgatgacaga tccagaagtt ctcattctcg atgaagcaac ttcaaacgta
    64321 gatacggtga cagaaagcaa gattcagcat gccatggagg tggttgtagc aggtagaact
    64381 agtttcgtca ttgcccaccg cttgaaaacc attctcaatg cagatcagat tattgtcctt
    64441 aaagatggag aagtcattga acgtggtaac caccatgaac ttttgaagct aggtggcttt
    64501 tattcagaac tctatcacaa tcaatttgtt ttcgaataag aaagaagttg tcctatgtgg
    64561 gcagcttttt cttgtccata aaaaatgttt atcacagcct taaaaaaaac atattagacg
    64621 aaagtcattt tgagtgatat gataggacta tcgttagcat tcgaaaggag aggcatcatg
    64681 gctagaacgg ttgtaggagt tgctgcaaat ctatgtcccg tagacgcaga aggcaaaatc
    64741 attcattcat ctgtatcttg tagattcgca gagatcattc gtcaagtcgg tggtctccct
    64801 ttagtcattc ctgttggtga tgagtcagtt gtacgtgatt atgtggaaat gattgacaaa
    64861 ctcattttga caggaggcca aaatgttcat cctcagtttt atggagagaa gaagaccgtc
    64921 gagagcgatg attacaatct ggtccgtgac gaatttgaat tggcactctt gaaggaagcg
    64981 cttcgtcaga ataaaccaat tatggcaatc tgtcgcggtg tccaacttgt caatgttgcc
    65041 tttggtggaa ccctcaatca agaaatcgaa ggtcactggc aaggactacc tttcgggaca
    65101 tctcactcta ttgagacagt agaaggaagc gtggtggcta agctatttgg gaaagaaagt
    65161 caggtcaact cagtccatcg tcaaagcatt aaagatttgg cacctaattt ccgtgtaact
    65221 gctattgatt caagagacca aactattgaa gcgattgagt ctatcgacga gcaccgcatt
    65281 atcggtttac agtggcatcc agagtttctg gttaatgaag aagatggcaa tttagaatta
    65341 tttgagtatt tattgaatga actgtaacga ttggaacatc tggtcgttct ttcttttatt
    65401 ttttcaaaat ttttagaatg tggcatttta cgcaaacgtt tgaattctga taaaaattgg
    65461 agaaattcga caaaaaaact tgaaaaaaac gaaggtaagc gttatgatag aaaagaagaa
    65521 atattggagg aagaacatgt cacatattaa atttgattat tcaaaagttt tagacaaatt
    65581 tgttgcacca catgaagtgg aatacatgca atcacaagta acagcagcag atgaattgat
    65641 ccgtaaagga actggtgctg gtagcgactt cttgggatgg ttggaccttc ctgaaaaata
    65701 cgaccgcgaa gaatttgacc gcatcttgaa agctgctgag caaatcaagt cagacagcga
    65761 tgttttggtt gtgatcggta ttggtggatc ttaccttggt gcaaaagcag caatcgactt
    65821 cttgaatcac cattttgcta acttgcaaac aaaagaagaa cgcaaagctc cacaaatcct
    65881 ttacgcagga aactcaatct catctactta ccttgctgac ttggtagagt atgttgcaga
    65941 caaagacttc tcagtaaacg taatttctaa atcaggtaca acaactgaac cagcgattgc
    66001 tttccgtgtc tttaaagaac tcttggttaa gaaatacggt caagaagaag ctaacaaacg
    66061 tatctatgca acaactgacc gccaaaaggg tgctgttaag gttgaagcag acgctaacgg
    66121 ttggggaaca tttgttgttc cagatgatat cggtggacgc ttctcagtat tgacagccgt
    66181 tggtttgctt ccaatcgcag catcaggagc tgacataaaa gctcttatgg aaggtgcgaa
    66241 tgcagctcgc aaagactaca cttcagacaa aatctctgaa aacgaagctt accaatacgc
    66301 agtcgttcgt aacatccttt atcgtaaagg ctatgcaact gagatcttgg taaactatga
    66361 gccatcactt caatacttct cagaatggtg gaaacaattg gctggtgaat cagaaggaaa
    66421 agaccaaaaa ggtatctacc caacttcagc caacttctca actgacttgc actcacttgg
    66481 tcaatttatc caagaaggaa ctcgtatcat gtttgaaaca gttgtccgtg ttgacaaacc
    66541 tcgtaaaaac gtgcttattc ctactttgga agaagacctt gacggacttg gttaccttca
    66601 aggaaaagac gttgactttg taaacaaaaa agcaactgac ggtgttcttc ttgcccacac
    66661 agatggtgat gtaccaaaca tgtatgtgac tcttccagag caagacgctt tcactcttgg
    66721 ttacactatc tacttcttcg aattggcaat tgccctttca ggttacttga atgctatcaa
    66781 cccatttgac caaccaggtg ttgaagctta taaacgtaac atgtttgccc ttcttggaaa
    66841 accaggattt gaagaattga gcaaagaact taacgcacgt ctataataga agaaaagagt
    66901 ggtttgccca ctctttttac tctctttatc catagaaatt ggactcagcc aagacttgtg
    66961 atataatata gaaagcaaaa aggcagacgc ctagataata ggagaaacta tgtcaaaaga
    67021 tatccgcgta cgttacgcac caagtccaac aggactacta cacatcggaa atgcccgtac
    67081 agcattgttt aactacttgt atgcgcgcca tcatggtgga acatttctca tccgtatcga
    67141 agatactgac cgtaaacgcc atgtcgagga tggtgaacgt tcacaacttg aaaaccttcg
    67201 ctggttaggc atggattggg atgaaagtcc agaatcacat gagaattatc gccagtctga
    67261 gcgtttggac ttgtatcaaa aatacatcga ccaactatta gctgaaggaa aagcctacaa
    67321 atcttacgtt acagaagaag agttggcagc tgaacgtgaa cgtcaagaag tagctggcga
    67381 aacaccacgc tacatcaatg aataccttgg tatgagtgaa gaagaaaaag cagcttacat
    67441 cgcagaacgt gaagcagcag ggatcatccc aactgttcgt ttggctgtca atgagtcagg
    67501 tatctacaag tggcatgata tggtcaaagg cgatatcgaa tttgaaggtg gcaatatcgg
    67561 tggtgactgg gttatccaaa agaaagacgg ttacccaact tacaactttg ccgttgttat
    67621 cgatgaccac gatatgcaaa tctctcatgt tatccgtgga gatgaccata ttgctaatac
    67681 accaaaacag cttatggtct atgaagctct tggttgggaa gctccagagt tcggtcacat
    67741 gaccttgatt atcaactctg agactggtaa gaagttatct aaacgtgata ctaatacact
    67801 tcaatttatc gaagattacc gaaagaaagg ttaccttcca gaagcagtct ttaactttat
    67861 tgctcttctt ggttggaacc caggtggtga agatgagatt ttctctcgtg aagaactcat
    67921 taaacttttt gatgaaaacc gcctcagcaa gtcaccagca gcctttgatc agaaaaaact
    67981 agactggatg agcaatgatt atatcaagaa tgcagacctt gaaaccatct ttgaaatggc
    68041 aaaaccattc ttagaggaag caggccgttt gactgacaag gctgaaaaat tagttgagct
    68101 ctataaacca caaatgaaat cagtagatga gattatccca ttgacagatc ttttcttctc
    68161 agatttccca gaattgacag aagcagagcg cgaagtcatg acgggtgaaa cagttccaac
    68221 agttcttgaa gcattcaaag caaaacttga agcgatgaca gatgataaat ttgtgacaga
    68281 aaatatcttc ccacaaatta aagcagttca aaaagaaaca ggtattaaag ggaaaaatct
    68341 tttcatgcct attcgtatcg cagtttcagg cgaaatgcat gggccagaat taccagatac
    68401 aattttcttg cttggacgtg aaaaatcaat tcagcatatc gaaaacatgc taaaagaaat
    68461 ctctaaataa agaggataca ataatggaca tctgggaaaa gatgtacgaa gaagcacaga
    68521 aactatacaa tccacatgaa gtatcagact ttgtttatgc caatcatgtt gtagctgcag
    68581 tagaagcaga agatggacaa atatttacag gattctgtat ggagggaacc tgtggtgttt
    68641 tccatctctg cgcagaacgg gcgaccctct tcaatatgta ccaattttca ggacaaacta
    68701 aggttaagaa agtattagcc tttcgagaca aaccacctta tggtggaagt tcagccatgc
    68761 cttgcggtgc ttgtagagaa ttccttttag agcttaatgc tgaaaataaa gatgcagaat
    68821 tcatgatgga ctataatata agaaaaacag ttaaagtcgc agaactaatc ccttattggt
    68881 ggggagaaga acgtgcttct aagtttaatg agcgatagaa gagtcagtat aattctggct
    68941 ttttttacta taagttgaaa aaat
//
LOCUS       DAVKEV010000003        55186 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVKEV010000003 DAVKEV010000000
VERSION     DAVKEV010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55186
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.003"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(1..313)
                     /locus_tag="VWZ68_000195"
                     /pseudo
     CDS             complement(1..313)
                     /locus_tag="VWZ68_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(408..593)
                     /locus_tag="VWZ68_000196"
                     /pseudo
     CDS             complement(408..593)
                     /locus_tag="VWZ68_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            621..848
                     /locus_tag="VWZ68_000197"
     CDS             621..848
                     /locus_tag="VWZ68_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9371298.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            924..1476
                     /locus_tag="VWZ68_000198"
                     /pseudo
     CDS             924..1476
                     /locus_tag="VWZ68_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2060..2536
                     /locus_tag="VWZ68_000199"
     CDS             2060..2536
                     /locus_tag="VWZ68_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9371299.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            2574..2879
                     /locus_tag="VWZ68_000200"
     CDS             2574..2879
                     /locus_tag="VWZ68_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9371300.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            2927..4402
                     /locus_tag="VWZ68_000201"
     CDS             2927..4402
                     /locus_tag="VWZ68_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU9371301.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNIVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            4428..4505
                     /locus_tag="VWZ68_000202"
                     /pseudo
     CDS             4428..4505
                     /locus_tag="VWZ68_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            4707..11408
                     /locus_tag="VWZ68_000203"
     CDS             4707..11408
                     /locus_tag="VWZ68_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEU9371302.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKTLKEDAKAVTNEEVNQMIENRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLYKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVKVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKDQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     VPKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKSLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEVTVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQGKVQFFA
                     DSGTDAPSKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAIKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSFPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKIEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGK
                     ERIFTAINPDGSKEEKLREVVEVPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPSTGSAASQAAVAAGLTLLGLSAGLVVTKGKKED"
     gene            complement(11656..12512)
                     /locus_tag="VWZ68_000204"
                     /pseudo
     CDS             complement(11656..12512)
                     /locus_tag="VWZ68_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12722..13081)
                     /locus_tag="VWZ68_000205"
     CDS             complement(12722..13081)
                     /locus_tag="VWZ68_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEU9371303.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            13104..13682
                     /locus_tag="VWZ68_000206"
     CDS             13104..13682
                     /locus_tag="VWZ68_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846832.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEU9371304.1"
                     /translation="METRNRGIYRKVRLLRLWVIFVIMKVMKSYNTLNDYYRKLFGEK
                     TFKVPIDAGFDCPNRDGTVAHGGCTFCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKW
                     PDVQKYLVYFQNFTNTHEKVEVVRERYEQAINEPGVVGINIGTRPDCLPDETIEYLAE
                     LSECMHVTVELGLQTTYEATSDLINRAHSYEL"
     gene            13683..14129
                     /locus_tag="VWZ68_000207"
     CDS             13683..14129
                     /locus_tag="VWZ68_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HEU9371305.1"
                     /translation="METVKRLRKYPKIEIVSHLINGLPGETHEMMVENVRRCVTNNDI
                     QGIKLHLLHLMTNTRMQRDYHEGRLQLMSQDEYVRVICDQLEIIPKHIVIHRITGDAP
                     RDMLLGLMWSLNKWEALNSIEMEMRRRGSVQGCKAVKQEFENEKTT"
     gene            14113..14670
                     /locus_tag="VWZ68_000208"
     CDS             14113..14670
                     /locus_tag="VWZ68_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9371306.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            14663..14917
                     /locus_tag="VWZ68_000209"
     CDS             14663..14917
                     /locus_tag="VWZ68_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371307.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            14929..16983
                     /locus_tag="VWZ68_000210"
     CDS             14929..16983
                     /locus_tag="VWZ68_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEU9371308.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            17162..18022
                     /locus_tag="VWZ68_000211"
     CDS             17162..18022
                     /locus_tag="VWZ68_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEU9371309.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            18233..18943
                     /gene="ccdA2"
                     /locus_tag="VWZ68_000212"
     CDS             18233..18943
                     /gene="ccdA2"
                     /locus_tag="VWZ68_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU9371310.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGFLVLFGNASILSQLFE"
     gene            18963..19529
                     /locus_tag="VWZ68_000213"
     CDS             18963..19529
                     /locus_tag="VWZ68_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEU9371311.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            19540..20652
                     /gene="msrB"
                     /locus_tag="VWZ68_000214"
     CDS             19540..20652
                     /gene="msrB"
                     /locus_tag="VWZ68_000214"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU9371312.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            21010..21747
                     /locus_tag="VWZ68_000215"
     CDS             21010..21747
                     /locus_tag="VWZ68_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9371313.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            21744..23435
                     /locus_tag="VWZ68_000216"
     CDS             21744..23435
                     /locus_tag="VWZ68_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9371314.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            23551..24114
                     /locus_tag="VWZ68_000217"
     CDS             23551..24114
                     /locus_tag="VWZ68_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEU9371315.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            24136..30078
                     /locus_tag="VWZ68_000218"
     CDS             24136..30078
                     /locus_tag="VWZ68_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEU9371316.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAEAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKSEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPREDEKAPVEPEKQPEAPEEEKAVEETPKQEDTQPEVVETKDEAANQP
                     VEEPKVETPAVEKQTEPTEEPKVEQVGEPVEPREDEKAPVSPEKQPEAPEEEKTAEET
                     PKQEDKIKGIGTKEPVDKSELNNQIDKASSVSPTDYSTASYNALGPVLETAKGVYASE
                     PVKQPEVNSETKAEKVAANTDAKQSEVNSETASLKTAISGLNTDKVELENQLKIAQGK
                     TETDFSMESWTVLSTAKNKAQEVKDNGTATQEQINEAEKSLKTALADLSVDKTALGSA
                     IDTATKKNKENYTNQTWAELETVLTAAKSVNTNESKQSEVNEAVEKLTATIEKLVELS
                     EKPRLTLSIEKRDIDRKVTVTYTLENPANTQIKSITATLKKGEEVVKDFVLTEENLKT
                     NHLTALFEKLDYYKEYTLSTDMVYNRGNDDETESISEELIQLNLKKLELKDIQTVSLM
                     KFENGQESQVTHLSDKPTDLSKLYLKVTSSTSKDAVLAVSSIEEEIVENKKIFKIHAD
                     TPELVVRKKDGSLSKGFDYYMERVIPHDGDIYYDFKDLISAMTSNPTGTFILGRDISS
                     RNVKPDGNGKSYIKGEFKGKLLGTNDNVRHSIFDLEYPLFDTIKSGVVKDIDFKHVNM
                     VFPDSNQGDNVATIARVIKDKTKIENVNVEGYLEGRDHVAGLVNNLEGNSEIENISFT
                     GKIKSKGGNSITAGIAGRNILSRVKRAYVNANIEVLGSTNSSMLVAVNGTTLNASGGW
                     GAWGRLTESVAKGTLEIKRSGQAGGVTATVWPYGAIDKVVSYAKVTKGKELFGSDGDL
                     NNNWFMQKINNIFGVQGISSGDSGNDSKFKRISEEEAKQKVASYNITAPNLMSDSSLL
                     VDRLNESWKNTDQFESIQDYQSQNQLIYQNLTKFTPYYNKEFIVHEGNALTPEQEILK
                     TKKIKSIVGLKGTEFVVDGSDIDTIMLHFEDGSQKRYKVTSTGKFSITNLPEYQVEDL
                     NVVYTSEHIVHPLDSSLINNLVEELKKVELYTESTYQVLGIDKDNANKLNRTKRLFLD
                     ESLDAVKTQLPTFVKTMFENEWLHINGESSGAVAALRQKIMDNKTAILLALTYINRYY
                     DVKFSDYNIKKLMLFKPTFHGEKIDLLDRLIRLGSSGENRLKGSENAETFKQLFASET
                     KQKDLVTYLDYNRSLLTNYQTTGEWFKETTKDYIQFEERPSLVEEIKDAKYRVYDNLT
                     APYYQGYILPLLTLKNTHLAILSNYSTMTFVSREKRPNWKNEDFDKWVKYVATAHRNH
                     VDTWYKILPDNIKGKMVKENVTAVWEGLSIPGSEWVDQNAVDRKGRDYAPAREFFNLV
                     GGPMGGWYAYHGYGAHAGGRNRVNYEVFDVLSEYGISVFTHELTHVNDTWIYLGGYGR
                     RENMGPEAYAQGLFQSPVPGQPGWGALGLNMAFERKNDGDLIYNASPTQFENRKELDS
                     YMKNYNDTLMMVDYLEGDAVISKGKEAITKWFKKVEPKVVSQTAQYDTVRQLTAEEKE
                     KLSVSSVDDLVDQGLMSDRAVGNNTYNPADFETSYIAIDYMTGIYGGGKNSVGSPGAL
                     MFKHNTFRMWGYYGFEEGVLGYASNKFKQASRDEGHAGLSDNFIISKISKGEFLTMEA
                     FKKGYFKKVVEELKTKGIRPVTINQKTYSTFEELQEGFKQAVERDLKKNQLDERETRN
                     FKFQVFRQLLQQTDSFKTSIFR"
     gene            30139..31860
                     /gene="pabB"
                     /locus_tag="VWZ68_000219"
     CDS             30139..31860
                     /gene="pabB"
                     /locus_tag="VWZ68_000219"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEU9371317.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKNLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            31861..32478
                     /locus_tag="VWZ68_000220"
     CDS             31861..32478
                     /locus_tag="VWZ68_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9371318.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SFMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            32528..33526
                     /locus_tag="VWZ68_000221"
     CDS             32528..33526
                     /locus_tag="VWZ68_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU9371319.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEREPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTV
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            33653..34612
                     /locus_tag="VWZ68_000222"
     CDS             33653..34612
                     /locus_tag="VWZ68_000222"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEU9371320.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            34709..35548
                     /locus_tag="VWZ68_000223"
     CDS             34709..35548
                     /locus_tag="VWZ68_000223"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEU9371321.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRIDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(35596..35766)
                     /locus_tag="VWZ68_000224"
     CDS             complement(35596..35766)
                     /locus_tag="VWZ68_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEU9371322.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            35887..36771
                     /gene="miaA"
                     /locus_tag="VWZ68_000225"
     CDS             35887..36771
                     /gene="miaA"
                     /locus_tag="VWZ68_000225"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEU9371323.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEGIHNRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            36764..38002
                     /gene="hflX"
                     /locus_tag="VWZ68_000226"
     CDS             36764..38002
                     /gene="hflX"
                     /locus_tag="VWZ68_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEU9371324.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            37995..38618
                     /locus_tag="VWZ68_000227"
     CDS             37995..38618
                     /locus_tag="VWZ68_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEU9371325.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            38633..39562
                     /locus_tag="VWZ68_000228"
     CDS             38633..39562
                     /locus_tag="VWZ68_000228"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEU9371326.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            39583..40338
                     /locus_tag="VWZ68_000229"
     CDS             39583..40338
                     /locus_tag="VWZ68_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU9371327.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(40392..41300)
                     /locus_tag="VWZ68_000230"
     CDS             complement(40392..41300)
                     /locus_tag="VWZ68_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU9371328.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            41364..41633
                     /locus_tag="VWZ68_000231"
     CDS             41364..41633
                     /locus_tag="VWZ68_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEU9371329.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            41633..42013
                     /locus_tag="VWZ68_000232"
     CDS             41633..42013
                     /locus_tag="VWZ68_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9371330.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            42131..42328
                     /locus_tag="VWZ68_000233"
     CDS             42131..42328
                     /locus_tag="VWZ68_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371331.1"
                     /translation="MGILSIILGLLFPIVGLILGIIGLVLAISYQKESQLDYKIEKIL
                     NILGIVISVVNWIVAIALIFR"
     gene            complement(42368..43093)
                     /locus_tag="VWZ68_000234"
     CDS             complement(42368..43093)
                     /locus_tag="VWZ68_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEU9371332.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            43255..45096
                     /gene="typA"
                     /locus_tag="VWZ68_000235"
     CDS             43255..45096
                     /gene="typA"
                     /locus_tag="VWZ68_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEU9371333.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPVEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            45116..45370
                     /locus_tag="VWZ68_000236"
     CDS             45116..45370
                     /locus_tag="VWZ68_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEU9371334.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            45734..46033
                     /locus_tag="VWZ68_000237"
                     /pseudo
     CDS             45734..46033
                     /locus_tag="VWZ68_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            46104..48125
                     /locus_tag="VWZ68_000238"
     CDS             46104..48125
                     /locus_tag="VWZ68_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9371335.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLIDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            48127..48768
                     /locus_tag="VWZ68_000239"
     CDS             48127..48768
                     /locus_tag="VWZ68_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9371336.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            48872..50224
                     /locus_tag="VWZ68_000240"
     CDS             48872..50224
                     /locus_tag="VWZ68_000240"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEU9371337.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQTASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            50228..51286
                     /locus_tag="VWZ68_000241"
     CDS             50228..51286
                     /locus_tag="VWZ68_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEU9371338.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            51296..52516
                     /gene="divIB"
                     /locus_tag="VWZ68_000242"
     CDS             51296..52516
                     /gene="divIB"
                     /locus_tag="VWZ68_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEU9371339.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQKDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGVYSYTVADKLIMEAEEKAKKEAEEAEKRQEEERKRLEEEQKKQEE
                     ESNRNQTTQRSSRR"
     gene            53303..54100
                     /locus_tag="VWZ68_000243"
     CDS             53303..54100
                     /locus_tag="VWZ68_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
                     /protein_id="HEU9371340.1"
                     /translation="MGLIDSMKSRKKINIFKISWDFNITLSEKLNYKRFNKNFEKILF
                     GIFPLALILQCFIMYIYRADILTNFQNFPITLNILLFWLLVVIISATIHEFSHAIIAN
                     NYQIEIPNCGIMLLLFNLAFFVDLSGVQFLKNKKQFLKIMLAGIASNSILSLTGLLVL
                     LFTSYKLLGLLFFIINLGMIFINSIPFFQYDSGIILRYLNSNNNNLNFQYIVQLLIAF
                     VIIYFPLSQLLQFLTPNIIVRSIGGVVVSILLSILYMRGRTKYVLRK"
     gene            54084..54272
                     /locus_tag="VWZ68_000244"
                     /pseudo
     CDS             54084..54272
                     /locus_tag="VWZ68_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828969.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            54309..55076
                     /locus_tag="VWZ68_000245"
                     /pseudo
     CDS             54309..55076
                     /locus_tag="VWZ68_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841312.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
BASE COUNT        17020 a         9935 c        12120 g        16111 t
ORIGIN      
        1 tttttgatat tcagagcgat gaaaatccgt tttttgaagt tttcaaagtt tcgaaaacca
       61 aaggcattgc gcttgataag tttgatgaga ttattggtcg cttccagttt ggcattagaa
      121 tagtgtagtt gaagggcatt gacaatcttc tctttatctt tgaggaaggt tttagaggat
      181 gaacctgatt cagattgtcc tcaatgagtc cgaaaaattt gtcaggctcc ttattctgaa
      241 agtgaaaaag caagagttga tagagattat agtggtgttt caagtcttct gaatagctca
      301 aaagtttatc tatagtagat tgaaactaga atagtacacc tctgcttcta aaacattgtt
      361 agaaatcgat ttgactgtcc tgaatgattt gtcctgttat tatttcattt tactataaat
      421 ccacgtttac gaatctcttt ccacacttgt tcaatggggt tcatctctgg tgtgtatgga
      481 ggaataaatg caaaaccaat attagtcgga atctttaagg tacttgattt atgccatata
      541 gcattgtcca taacgagtaa aagataatca tctggataag cttgtgaaag ctcctattcc
      601 taaagcccct ttataacctc ttgcgagaga gactattgac tcagccctta cttcatgcgg
      661 atgaaacttc ttatcgggtt ctagagagtc atagccatct gacctactat tggacctttt
      721 tgtctgggaa agttgagaat caagcaatca cgctgtacca tcatgatcag agtcggagtg
      781 gttcggtagt acaagaattc ctaggagatt attctggcta tgttcattgt gatatgttgc
      841 ggcagtaact taggacttta gtcctctagt tctgcctatg cgatagcagt ccaaggttta
      901 ggagcaaggc gacgctaagc ttggtaaact gcgaactgct agaagcttat cgtcaactgg
      961 aagaagctga acttgttgga tgttgggcgc atgtgagaag gaaatttttt gaagcgaccc
     1021 ccaagcaagc agataaatca tccttaggag ctaaaggttt agcttattgt gatcagttat
     1081 tttccttgga aagagactgg gaggctttgc cagctgatga acgactacag aaacgtcaag
     1141 aacatctcca gcccctaatg gaagacttct ttgcttggtg ccgccgtcag tcagttttag
     1201 caggttcaaa actaggaagg gcaattgaat acagcctcaa gtatgaagaa acctttaaga
     1261 ctattttgaa agacggacat ctggtccttt ccaataatct agctgaacgc gccattaaat
     1321 cattggttat gggacggagt aaaagagtcc agtggactct tttagcctga gctcagttta
     1381 aaaaagcgag ggtggttatt ttctcaaagt tttgaaggag ctaaagcaag agctattatt
     1441 atgagcttgt tggaaacagc taaacgtcat caattatagt gcgttgaatc tataacagta
     1501 cgcatcgact gctaaaacat ttctataaat caattttcct ttcctaatcg atttgttcat
     1561 atcttatttc aatccattat aaatagcgag aaatatctat cctatcttct agaatgtctt
     1621 ccaaacgagg aaactctcgt aaacaaagag gttttagagg cctatttacc atggactaaa
     1681 gttgtacaag aaaagtgcaa ataagaaatc tccagattag gaactatccg tgagttcact
     1741 aatctggaga tttttcaata gacttcgtta ttgggcggtt acgatatgat cactgacttc
     1801 gtcagtctta tctacaacct caaaactgtg ttttgagcaa cctgcggcta gcttcctagt
     1861 ttgctctttg attttcattg agtattagaa cagaaaaaat acttggagta tttgtttgtg
     1921 tgtttatttt tatataacaa actataaaca aaacaaaaat ataaaaaaag agacaaaaaa
     1981 agaacagaaa gcaattgaca acggtttcat atagtgttat acttatggca taaagttaat
     2041 ggaaagaagg gaaaaactta tggtattaga ttatttcttt gacaaaaacc ttgtgttttg
     2101 cttagaagcg gataatcaag aacaactctt tgatcaggtt gcaactttat tggaagaacg
     2161 agaaattgtc actccaactt atcgtgaagc cttgatcacg cgtgaaaagt catttccaac
     2221 tggtttagat atggaatttc taggaaagga cttgccaaat gtagcgattc ctcatacaga
     2281 tattgttcat aatctagctg agaaagtggt ggttgttcga ttagaaaaac cagtaacttt
     2341 tcacaatatg atagctcctg ataaggaagt agaagtatcc ctactcttct ttattattaa
     2401 caattcaagt tcaagtcaaa caaatattct ggctcagttg atggactttt tcacaggaaa
     2461 tggacatctt gaagacctat caaaaatttc cgaaccagaa aaactttatg cttacattgc
     2521 tgaagcaacc gcttaatctt gtctattaaa aaataaaatc ggaggaaatc caaatgatta
     2581 aaattcttgc tgcctgcggt gcaggtgtta actcaagtca ccaaattaaa agtgctctag
     2641 aagaagaact ttcaaaccgt ggttatgatg ttcactgtga tgcagtcatg gtgaaagatg
     2701 taaacgaaga ccttatgaaa ggttacgata tctttacacc aatcgctgca acagaccttg
     2761 gttttgaacc aggtatccca gttatcgaag ctgggccaat cttattccgt atcccagcaa
     2821 tgagcgctcc agtatttgac aatattgaag cagctattaa agaacacgga ttaagctaat
     2881 tctaatttgt taacattcat ataacataaa aaagggagga actgttatgg atgcaatctt
     2941 tgacctaatc ggaaaggttt tcaatcccat tttagaaatg ggtggacctg tcatcatgtt
     3001 aatcattttg acagtattgg ctttactttt tggagtgaaa ttctccaaag cgcttgaagg
     3061 tggtatcaaa cttgccatcg ctcttacagg tatcggtgct atcatcggta tgctaaatgg
     3121 tgctttctca gcatcacttg caaaattcgt tgaaaacact ggtatccaat tgagtattac
     3181 cgacgttggt tgggcaccac tcgcaacaat cacttggggt tctgcttgga cactatactt
     3241 cttgctcatc atgttgattg tcaacatagt gatgctagct atgaagaaaa cagatacact
     3301 tgacgttgat atctttgata tctggcactt gtctatcaca ggtctcttga ttaaatggta
     3361 tgctgataac aatggtgtga gtcaaggggt ttcactcttt attgctacag cagctatcgt
     3421 ccttgtcggt gtgttgaaaa ttatcaactc tgacttgatg aaacctacat ttgatgacct
     3481 tcttaacgcc ccaagttcat caccaatgac atcaactcac atgaactaca tgatgaaccc
     3541 agttatcatg gttttggata agatttttga aaaattcttc ccaggccttg ataaatatga
     3601 ctttgatgct gctaaattga acaagaaaat cggtttctgg ggatctaaat tcttcatcgg
     3661 tttcatcctt ggtatcgtta tcggtattat gggaactcca catccaattg caggtgttgc
     3721 agatgcagat aaatggcgtc ttgttatcaa aggatggttg tctcttggtt tgactgccgg
     3781 tgtatctttg gaactcttct cacttatcgg ttcatggttc atcgcagccg tagaaccact
     3841 atcacaaggt attacaaacg ttgctactaa acgtcttcaa ggacgtaaat tcaatatcgg
     3901 tcttgactgg ccattcatcg ctggtcgtgc tgaaatctgg gcttgtgcca acgtacttgc
     3961 accaatcatg ttgattgaag cagtgcttct ttcaaaagtt ggaaatggta tcttgccact
     4021 tgcaggtatc atcgctatgg gtgttactcc agctctcttg gttgtaactc gtggtaaatt
     4081 gctccgtatg attatcttcg gaacactctt gttgccactc ttccttcttt caggtacact
     4141 tattgcacca tttgcaacag aacttgctaa aggtgtaggt gccttcccag aaggtgtgag
     4201 ccaaactcaa ttgattactc actctactct tgaaggacca atcgaaaaac ttcttggttg
     4261 gacaattggt aacactacaa ctggtgatat caaagcaatc cttggtgcag tagtcttcct
     4321 tgtattctat atcggtatct ttgcttggta cagaaaacaa atgatcaaac gtaacgaaga
     4381 gtacgcagca aaagcaaaat aatgcgctcc tataaaatat aaactcaatg aaaatcaaag
     4441 agcaaactag gaaactagcc acaggttgct caaaacacag ttttgaggtt gtagataaga
     4501 ctgacgaagt cagctcaaaa catggttttg aggttgtaga tgaaactgac gaagtcagta
     4561 atcatatcta cggcaaggcg acactgacga agtttgaatt ggattttcgc agagtgtaaa
     4621 ttgttgaaac taggttgtca taccatgtat accacttggg ctttggcagt agctaactgc
     4681 actaaatata atataaggag ggttttatgg ggaaaggcca ttggaatcgg aaaagagttt
     4741 atagcattcg taagtttgct gtgggagctt gctcagtaat gattgggact tgtgcagttc
     4801 tattaggagg aaatatagct ggagaatctg tagtttatgc ggatgaaaca cttattactc
     4861 atactgctga gaaacctaaa gaggaaaaaa tgatagtaga agaaaaggct gataaagctt
     4921 tggaaactaa aaatgtagtt gaaaggacag aacaaagtga acctagttca actgaggcta
     4981 ttgcatctga gaagaaagaa gatgaagccg taactccaaa agaggaaaaa gtgtctgcta
     5041 aaccggaaga aaaagctcca aggatagaat cacaagcttc aagtcaagaa aaaacgctca
     5101 aggaagatgc taaagctgta acaaatgaag aagtgaatca aatgattgaa aacaggaaag
     5161 tggattttaa tcaaaattgg tactttaaac tcaatgcaaa ttctaaggaa gccattaaac
     5221 ctgatgcaga cgtatctacg tggaaaaaat tagatttacc gtatgactgg agtatcttta
     5281 acgatttcga tcatgaatct cctgcacaaa atgaaggtgg acagctcaac ggtggggaag
     5341 cttggtatcg caagactttc aaactagatg aaaaagacct caagaaaaat gttcgcctta
     5401 cttttgatgg cgtctacatg gattctcaag tttatgtcaa tggtcagtta gtggggcatt
     5461 atccaaatgg ttataaccag ttctcatacg atatcaccaa atacctttac aaagatggtc
     5521 gtgagaatgt gattgctgtc catgcagtca acaaacagcc aagtagccgt tggtattcag
     5581 gaagtggtat ctatcgtgat gtgactttac aagtgacaga taaggtgcat gttgagaaaa
     5641 atgggacaac tattttaaca ccaaaacttg aagaacaaca acatggcaag gttgaaactc
     5701 atgtgaccag caaaatcgtc aatacggacg acaaagacca tgaacttgta gccgaatatc
     5761 aaatcgttga acgaggtggt catgctgtaa caggcttagt tcgtacagcg agtcgtacct
     5821 taaaagcaca tgaatcaaca agcctagatg cgattttaga agttgaaaga ccaaaactct
     5881 ggaccgtttt aaatgacaaa cctgccttgt acgaattgat tacgcgtgtt taccgtgacg
     5941 gtcaattggt tgatgctaag aaggatttgt ttggttaccg ttactatcac tggactccaa
     6001 atgaaggttt ctctttgaat ggtgaacgta ttaaattcca tggagtatcc ttgcaccacg
     6061 accatggggc gcttggagca gaagaaaact ataaagcaga atatcgccgt ctcaaacaaa
     6121 tgaaggagat gggagttaac tccatccgta caacccacaa ccctgctagt gagcaaacct
     6181 tgcaaatcgc agcagaacta ggtttactcg ttcaggaaga ggcctttgat acttggtatg
     6241 gtggcaagaa accttatgac tatggacgtt tctttgaaaa agatgccact cacccagaag
     6301 ctcgaaaagg tgaaaaatgg tctgattttg acctacgtac catggtcgaa agaggcaaaa
     6361 acaaccctgc tatcttcatg tggtcaattg gtaatgaaat aggtgaagct aatggtgatg
     6421 cccactcttt agcaactgtt aaacgtttgg tcaaggttat caaggatgtt gataagactc
     6481 gctatgttac catgggagca gataaattcc gtttcggtaa tggtagcgga gggcatgaga
     6541 aaattgctga tgaactcgat gctgttggat ttaactattc tgaagataat tacaaagccc
     6601 ttagagctaa gcatccaaaa tggttgattt acggttcaga aacatcatca gcaacccgta
     6661 cacgaggaag ttactatcgc cctgaacgtg aattgaaaca tagcaatgga cctgagcgta
     6721 attatgaaca gtcagattat ggaaatgatc gtgtgggttg ggggaaaaca gcaaccgctt
     6781 catggacttt tgaccgtgac aacgctggct atgctggaca gtttatctgg acaggtacgg
     6841 actatattgg tgaacctaca ccatggcaca accaaaatca aactcccgtt aagagctctt
     6901 actttggtat cgtagataca gccggcattc caaaacatga cttctatctc taccaaagcc
     6961 aatgggtttc tgttaagaag aaaccgatgg tacaccttct tcctcactgg aactgggaaa
     7021 acaaagaatt agcatccaaa gtagctgact cagaaggtaa gattccagtt cgtgcttatt
     7081 cgaatgcttc tagtgtagaa ttgttcttga atggaaaatc tcttggtctt aagactttca
     7141 ataaaaaaca aaccagcgat gggcggactt accaagaagg tgcaaatgct aatgaacttt
     7201 atcttgaatg gaaagttgcc tatcaaccag gtaccttgga agcaattgct cgtgatgaat
     7261 ctggcaagga aattgctcga gataagatta cgactgctgg taagccagcg gcagttcgtc
     7321 ttattaagga agatcatgcg attgcagcag atggaaaaga cttgacttac atctactatg
     7381 aaattgttga cagccagggg aatgtggttc caactgctaa taatctggtt cgcttccaat
     7441 tgcatggtca aggtcaactg gtcggtgtag ataacggaga acaagccagc cgtgaacgct
     7501 ataaggcgca agcagatggt tcttggattc gtaaagcatt taatggtaaa ggtgttgcca
     7561 ttgtcaaatc aactgaacaa gcagggaaat tcacccttac tgcccactct gatctcttga
     7621 aatcgaacca agtcactgtc tttactggta agaaagaagg acaagagaag actgttttgg
     7681 ggacagaagt gccaaaagta cagaccatta ttggagaggc acctgaaatg cctaccactg
     7741 ttccgtttgt atacagtgat ggtagccgtg cagaacgtcc tgtaacctgg tctcaagtcg
     7801 atgttagtca agcaggagtt gtgactgtta aaggtacagc aaatggacgt gaggtagagg
     7861 ctcatgtcaa ggttctagca attgcgaaag aattaccaac agttaaacgt attgctccaa
     7921 atactgactt gaattctgta gacaaatctg tttcttatgt tttgactgat ggaagtgtac
     7981 aagagtacga agtagatagc tgggagatta cggaagtaga taaagccaaa ctttcagtag
     8041 ctggatcacg tattcaaatg actggtcagt tagctggaga aactattcat gcaacccttg
     8101 tggtagaaga aggaaatgct gcagcacctg tagtgccaac tgttactgtt ggaggtgaag
     8161 cagtaacagg tcttactagt cgacaaccaa tgcaatatcg tactctatct tatggtgccc
     8221 aattgccaga agtcacagca agtgctgaaa atgctgatgt gacagttctt caagcaagcg
     8281 cagcaaacgg catgcgtgcg agcatcttta ttcagcctaa agatggtggc cctcttcaaa
     8341 cctatgcaat tcaattcctt gaagaagcgc caaaaattgc tcacttgagc ttgcaagtgg
     8401 aaaaagctga cagtctcaaa gaagaccaaa ctgtcaaatt gtcggttcga gctcactatc
     8461 aagatggaac gcaagctgta ttaccagctg ataaagtaac cttctctaca agtggtgaag
     8521 gggaagtcgc aattcgtaaa ggaatgcttg agttgcataa gccaggagca gtcactctga
     8581 acgctgaata tgagggagct aaagaccaag ttgaactcac tatccaagcc aatactgaga
     8641 agaagattgc gcaatccatc cgtcctgtaa atgtagtgac agatttgcat caggaaccaa
     8701 gtcttccagc aacagtaaca gttgagtatg acaaaggttt ccctaaaact cataaagtca
     8761 cttggcaagc tattccgaaa gaaaaactag actcctatca aacatttgaa gtactaggta
     8821 aagttgaagg aattgacctt gaagcgcgtg caaaagtctc tgtagaaggt atcgtttcag
     8881 ttgaagaagt cagtgtgaca actccaatcg cagaagcacc acaattacca gaaagtgttc
     8941 ggacatatga ttcaaatggt cacgtttcat cagctaaggt tgcatgggat gcgattcgtc
     9001 cagagcaata cgctaaggaa ggtgtcttta cagttaatgg tcgcttagaa ggtacgcaat
     9061 taacaactaa acttcatgtt cgcgtatctg ctcaaactga gcaaggtgca aacatttctg
     9121 accaatggac cggttcagaa ttgccacttg cctttgcttc agactcaaat ccaagcgacc
     9181 cagtttcaaa tgttaatgac aagctcattt cctacaataa ccaaccagcc aatcgttgga
     9241 caaactggaa tcgtactaat ccagaagctt cagtcggtgt tctgtttgga gattcaggta
     9301 tcttgagcaa acgctccgtt gataatctaa gtgtcggatt ccatgaagac catggagttg
     9361 gtgtaccgaa gtcttatgtg attgagtatt atgttggtaa gactgtccca acagctccta
     9421 aaaaccctag ttttgttggt aatgaggacc atgtctttaa tgattctgcc aactggaaac
     9481 cagttactaa tctaaaagcc cctgctcaac tcaaggctgg agaaatgaac cactttagct
     9541 ttgataaagt tgaaacctat gctgttcgta ttcgcatggt taaagcagat aacaagcgtg
     9601 gaacgtctat cacagaggta caaatctttg cgaaacaagt tgcggcagcc aagcaaggac
     9661 aaacaagaat ccaagttgac ggcaaagact tagcaaactt caaccctgat ttgacagact
     9721 actaccttga gtctgtagat ggaaaagttc cggcagtcac agcaagtgtt agcaacaatg
     9781 gtctcgctac cgtcgttcca agcgttcgtg aaggtgagcc agttcgtgtc atcgcgaaag
     9841 ctgaaaatgg cgacatctta ggagaatacc gtctgcactt cactaaggat aagagcttac
     9901 tttctcataa accagttgct gcggttaaac aagctcgctt gctacaagta ggtcaagcac
     9961 ttgaattgcc gactaaggtt ccagtttact tcacaggtaa agacggctac gaaacaaaag
    10021 acctgacagt tgaatgggaa gaagttccag cggaaaatct gacaaaagca ggtcaattta
    10081 ctgttcgagg ccgtgtcctt ggtagtaacc ttgttgctga ggtcactgta cgagtgacag
    10141 acaaacttgg tgagactctt tcagataacc ctaactatga tgaaaacagt aaccaggcct
    10201 ttgcttcagc aaccaatgat attgacaaaa actctcatga ccgcgttgac tatctcaatg
    10261 acggagatca ttcagaaaat cgtcgttgga caaactggtc accaacacca tcttctaatc
    10321 cagaagtatc agcgggtgtg attttccgtg aaaatggtaa gattgtagaa cggactgttg
    10381 cacaaggaaa agttcagttc tttgcagata gtggtacgga tgcaccatct aaactcgttt
    10441 tagaacgcta tgtcggtcca gagtttgaag tgccaaccta ctattcaaac taccaagcct
    10501 acgacgcaga ccatccattc aacaatccag aaaattggga agctgttcct tatcgtgcgg
    10561 ataaagacat tgcagctggt gatgaaatca acgtaacatt taaagctatc aaagccaaag
    10621 ctatgagatg gcgtatggag cgtaaagcag ataagagcgg tgttgcgatg attgagatga
    10681 ccttccttgc accaagtgaa ttgcctcaag aaagcactca atcaaagatt cttgtagatg
    10741 gaaaagaact tgctgatttc gctgaaaatc gtcaagacta tcaaattacc tataaaggtc
    10801 aacggccaaa agtctcagtt gaagaaaaca atcaagtagc ttcaactgtg gtagatagtg
    10861 gagaagatag ctttccagta cttgttcgcc tcgtttcaga aagtggaaaa caagtcaagg
    10921 aataccgtat ccacttgact aaggaaaaac cagtttctga gaagacagtt gctgctgtac
    10981 aagaagatct tccaaaaatc gaatttgttg aaaaagattt ggcatacaag acagttgaga
    11041 aaaaagattc aacactgtat ctaggtgaaa ctcgtgtaga acaagaagga aaagttggaa
    11101 aagaacgtat ctttacagcg attaatcctg atggaagtaa ggaagaaaaa ctccgtgaag
    11161 tggtagaagt tccgacagac cgcatcgtct tggttggaac caaaccagta gctcaagaag
    11221 ctaaaaaacc acaagtgtca gaaaaagcag atacaaaacc aattgattca agtgaagcta
    11281 gtcaaactaa taaagcccag ttaccaagta caggtagtgc ggcaagccaa gcagcagtag
    11341 cagcaggttt aactcttcta ggtttgagtg caggattagt agttactaaa ggtaaaaaag
    11401 aagactagaa attttgatac cttctttatc attaaagacc aaagaaaaac tcttgtccta
    11461 aatagaagat aaagagcctg agacaaaata gttctcaacc acaaaaaagc tagatatttc
    11521 caattgtgga actctagctt tttaattttg agtcattctc ttattgtata gtagattgaa
    11581 actagaatag tacactttta cttctaaaac attgttagaa atcgatttga ttgtccttat
    11641 cgatttgtcc tgttcttatt tcattttact atattttagg aggttattgg ccataagtac
    11701 caatcccatg tcaattctca cttgacgctt ccctctcaga ttacatctct tgtaacccaa
    11761 agaagccttt atctgcccaa agacaggttc cacatcaatc ttgcgttgag cgaaaatctg
    11821 tctaccttgg ggagataaaa gcgcctgaca ttctttagct ttcaagtttt gatagcgttc
    11881 gttcatatac agtccctttt gaggggctga ttcaggttcg tcggcgtagt aaaccttgat
    11941 ttcttgttga aagtctgtct gtgttttctg atatttggta tggtgaaaac gataatacca
    12001 gccatcagga tgtgtgtagc tatcctcctt gtcattatag tgccaattcg ctaagttttt
    12061 agctgactct ttataccctc tcttttgttt cttatcaaac atggcatatt taatcagaag
    12121 gggagtgatt tcttcttgaa aatagacctg tatctgttct tgaagtttgg cggagaattt
    12181 ctctgtcgtt ttcttccaca caaaactata cttgttggca ttggcttcaa tcttagttct
    12241 gtcaataaac aaacaatcta aggtcactaa ctcttccatt tttcaatttt tcgaccagag
    12301 aaaatccctt gtgaataggc aaatagaaga gtagatacaa gcattttagg gtgataagac
    12361 gggcgatcaa aggcatgata ggaggtgtag aagtgacgtt cctccaaggt attcaccact
    12421 ttttcaatag taaaaacgag atgatcttgt ggtaagaagg aactgatttc tagtggtaaa
    12481 gttgtttgat ttgtgttata gtgaatatgc atgggatagc ctttctaaat ggtttattgg
    12541 gcaattctat tttaccaaga ctatcgtaac catgcaaaaa agcaacggca aatccgttgc
    12601 ctttttggat ataagagact attgtcccag actcttttct ttgtataaaa ttgtatagtg
    12661 ttattgtcta tactattttg tagagaaagc aaaaatccct agaaaatgct tagggattcg
    12721 actatttcat taagaacaat tcaacaatca tttctatata catgataagg gttaataaga
    12781 atcctgcacg ccagaagaat ttgataaatt taggatagta aaagctgcgt tttttcaaaa
    12841 ggaagaaaaa gacgagaata atggctagga tcgagagggc tagccccagt ctagggagga
    12901 aattatgggt aaaggtttta gctgtaatca agtaatactc aaataccaag actggaaaag
    12961 ccaaatccgc aaagtttcgt cctagttttt ttaatctaaa aagtttggtt aggataatgc
    13021 agacgactaa ggtcagtatc aataataaaa tagatgctaa tttcattaaa atcataccca
    13081 tattgtatca taaaaaaagg ctaatggaaa cgagaaacag aggaatttat aggaaagtca
    13141 ggcttttgag attgtgggtg atttttgtta taatgaaagt catgaaatct tataatacct
    13201 tgaatgatta ttatcgaaaa ctctttggag aaaagacttt taaagtccct attgatgcgg
    13261 gatttgactg tcccaatcgt gatggaactg tggctcatgg aggctgtact ttttgtacgg
    13321 tttcaggttc tggagatgct attgtagccc cagatgcgcc tatccgtgag caattttata
    13381 aggaaattga ctttatgcac cgtaagtggc cggatgttca gaagtatctg gtttattttc
    13441 aaaattttac caacacccat gaaaaggtgg aagttgttcg agagcgttat gaacaggcta
    13501 tcaatgagcc aggtgtggta ggtatcaata ttggaacgcg cccagactgt ttaccagacg
    13561 aaaccatcga atatttggct gagttatcgg agtgcatgca tgtgacggtt gaattgggct
    13621 tgcaaactac ttatgaagca acctctgacc tgattaaccg tgcgcattct tatgaattgt
    13681 aggtggaaac ggtcaagcgt ttgagaaagt atccaaaaat tgagattgtt tcccatttga
    13741 tcaatggttt gcctggtgaa acccatgaga tgatggttga aaatgtccgc cgttgtgtca
    13801 cgaataacga tattcaaggg attaaactgc atttgctcca tcttatgaca aatactcgta
    13861 tgcaacgaga ttaccatgag ggacgtttac aattgatgag tcaggacgaa tatgtcaggg
    13921 tcatctgtga ccaactggaa atcattccca aacatatcgt catccatcga attacaggag
    13981 atgcgcctag ggatatgctg cttgggctta tgtggagcct caataaatgg gaagctctca
    14041 acagcattga gatggagatg cgacgtcgtg gaagtgttca aggatgcaag gctgtaaaac
    14101 aggagtttga aaatgaaaag accacttgag atggcacatg attttttggc tgaggtcgtg
    14161 acaaaagagg atgtcgtagt ggatgcgact atgggaaatg gtcatgacac gcttttttta
    14221 gccaagctag ccaagcaagt ctatgccttt gatattcaga agcaagcctt ggaaaagacc
    14281 caagagcgtt tgcatcaggc tggcttgaca aatgcccagt taatcttgca aggccatgag
    14341 acactggacc agtttgtgac aaaagctaag gcagggattt ttaatttggg ctatttgccg
    14401 tcagctgata agtctgtcat cacccgaccg cagacaacga ttgaggcatt agaaaagcta
    14461 tgtggcttac ttgtcaaagg tggacgaatt gctattatga tttactatgg tcatgaagga
    14521 ggcgacctcg agagagatgc tgtcttggat tttgtgatcc agttgaacca acaagagtac
    14581 acagctgcca tttaccgaac tttaaaccaa gtcaacaacc cgccgttttt agtgatgatt
    14641 gaaaaattag agagatacag acatggataa acaataccta cacgaaaagc tggatgccat
    14701 gcgccagaat tttgttgaat caacccacca cgaacgagcg gtgggcgtgc tagaccaagc
    14761 gcatatgagc aaaaaaatgc ttaaaatcaa gaaaaaatta gttgctcttg aaatggaacg
    14821 gtgccagaga aaaattgagc acaaagactg ttccaagatt gaccaaaaaa tcaaagagca
    14881 gaaggagata tttgaatcct gttgtaaaaa agattaagga ggacgtgcgt ggaattactg
    14941 atttacctca tcctattttt actggttttg attgtctcaa gtacaaccaa taagctcctg
    15001 ccctttttgc ctctcccttt ggtgcagatt cttttgggaa ttgtgattgg tctcttttta
    15061 cccaatactg actttcacct taatacggag ttgtttttgg cactggttat cggacccttg
    15121 cttttccgag aggctgaaga agcagatgtt acggctattt taaaacactg gcgaatcatt
    15181 gtttatctca tatttccagt gatttttatc tcgaccctga gtttgggtgg cttggcccat
    15241 cttctttggt tcagccttcc cttggcagct tgcttggctg ttggtgcagc ccttggtcct
    15301 acggacttgg tggcctttgc ctctctttcg gagcgtttta gctttcctaa gcgcgtgtcc
    15361 aatattctta agggcgaagg actcttgaat gatgcttctg gtttggtggc ttttcaggta
    15421 gctttgacag cttggacaac tggagctttt tctctggggc aagctagcag ttcgctcatc
    15481 ttttcaatcc taggcggttt tttaattgga tttttaacag ccatgaccaa ccgcttcctc
    15541 cataccttct tgctaagtgt gcgcgcaacg gatattgcca gtgaactttt attagaattg
    15601 agtttgcctc tagtgacctt ctttctggca gaagaagtcc atgtttcagg gattattgcc
    15661 gtcgtagttg ctggaatttt aaaggcaagt cgcttcaaga aaatcacgct cctcgaagcc
    15721 caagtggata cggtgaccga gacggtctgg catacagtga cctttatgct caacggttct
    15781 gtctttgtga ttttagggat ggagttggaa atgatagcag aacctatctt gaccaatcca
    15841 atctataatc ctctactttt attgctatct ctcatcgccc ttacctttgt cctctttgtc
    15901 attcgtttta ttatgatcta tggctattat gcctatagaa cccgacgcct caagaaaaag
    15961 ctaaataagt atatgaagga catgtttctc ttgacctttt caggtgttaa gggaacggtg
    16021 tcgattgcta cgattctctt gataccaagt aatctagaac aggagtatcc tctcttgctt
    16081 ttccttgttg caggtgtgac gcttgtcagc tttttaacag gtctcttggt cttgcctcat
    16141 ctttctgatg aagaggaaga aagcaaggat tatctcatgc atatcgccat tttgaatgaa
    16201 gtaacgctag agttggaaaa agagttggaa gacaccagaa ataaacttcc cctctatgcg
    16261 gctattgaca attatcatgg acgtattgaa aatctcattt taagccaaga aaaccaggat
    16321 gatcaagaag attgggctgc tttgaaactc ttgattctta gtattgaaag tgatggtttg
    16381 gagcaggcct atgaagaggg gaacattagc aatcgtgctt accgagttta ccaacgttat
    16441 ctgaaaaata tagaacaagg aatcaatcgt aaacttgcct caagactgac ctattatttc
    16501 cttgtttctt tgcggatttt acgttttctc cttcatgaag tttttactct cggaaagacc
    16561 ttccgtagct ggaagaacaa ggagcaaagc cgtctccgtg ctcttgatta tgaccaaatt
    16621 gcagagctct atcttgccaa tacagagatg attattgaaa gtttggaaaa cctgaaggga
    16681 gtctacagac gctctttgat tagttttatg caggagtctc gtcttcgaga aacagctatt
    16741 atcagcagtg gtgcctttgt cgaacgggtt atcaatcgtg tcaaacccaa caatatcgat
    16801 gaaatgctga gaggctatta tctggagcgc aagttgattt tcgaatacga agaaaaacga
    16861 ttgattacga ctaagtatgc caagaaatta cgacaaaatg taaataactt agagaactat
    16921 tccttgaagg aagctgccaa taccctaccg tatgatatgg tggaattggt aagaagaaat
    16981 tagttaatac tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttac cgtatgtatg
    17041 tgactgactt cgtcagtctt atctacaacc tcaaaacagt gttttgagca gcttgcggct
    17101 agctttctag tttgctcttt gattttcatt gagtataaga ttataaatga aggagtatga
    17161 catgaaaaag tggtggaaag agctgataga caaaccttta ttaaaagctt ttttgcatta
    17221 ttatcaagca tcagatagtg agttgaccag tgtcgcagta gcctactatt ggttgatttc
    17281 gattttcccc ctgcttttgg tggtggtcaa tatcctcccc tattttcaga ttcctgtggg
    17341 agaatttttg ggctttatga aagacgtcct gcccccaagc ctctatgaag gtgtggaaaa
    17401 aatagccaga gaagtcttga cgcaaccttc aacaggttta ttgagttttt ctgttttatc
    17461 ggcgttatgg agtttttcaa aatctatgaa tttcttgcaa aaagctttta acaaggctta
    17521 tggcgtcgaa aagagtcgtg gacttatttc ccatcagatg ctaagtctcc tagtcagttt
    17581 tggcttgcag ctcctctttg cgtttgcctt gtttttgatc ttatttggtc agatgatttt
    17641 ggctttactt gctcattatt ggacaaaaga tggcattatc tatcaggctt tacaagggtt
    17701 ggcaggtcct ctgatttacg ccctcctctt tgctatcttg gtcatgcttt attattttct
    17761 tcccaatcta tctaacagga aaattagcta taccctacca ggcagtgcct ttgttctctt
    17821 agtgatttta ggtttactaa ctctgttctc tagttatctc aattactatg tccatcattt
    17881 ggtggatgtc cgaattttag gttccgttct tcttgttgtt atgatgtttt ggtttatctt
    17941 gattgctaaa attgttatcc taggcgcggt gatcaatgcc agtatgcaga gtttgaaaga
    18001 tccggtcttt aaaaaagact aactatttat ccattacaaa agcgcatagt atcaagattc
    18061 tataaagcct tgatactatg cgcttttgtg ctttgacagt tttttgtata gtttttgtcc
    18121 aagatttcta aatcatctga ttaaattcct attttcccct atcattgtcc ctgttttttc
    18181 gaaaatggaa ggagtataat aaatctatca ataaaatgat aggaggaact ttatgggtca
    18241 tattttcttt tttctaagtg tctttttggc agggattcta tccttctttt ctccttgtat
    18301 cttacctttg ttaccggtct atacaggagt gttactagat gataaggatg gtgctcaggc
    18361 ttctagcggc aaattttcaa tctcagttac tagtttatta cgaactctgg cctttatagc
    18421 aggaatttcc tttatattta ttttgttggg ctatggagct ggttttttag gcgatttgct
    18481 ttatgcttct tggttccaat atcttactgg ggcaattatt atccttcttg gtttgcacca
    18541 aatggagatt ctacacttta aggggcttta taaggaaaag aggctacaac tgcaaggaca
    18601 ggggcaaaat ggtaagggct atagtcaggc atttttattg ggcttgacct ttagttttgc
    18661 ttggacgcct tgcgtggggc cggttctggg gtctgttttg gccttggcgg cttcaggtgg
    18721 ttcaggagct tggcagggag ctggtctcat gttggtgtat acgctgggct tggcgctacc
    18781 attcttgctt ctagctctga cctctagtta tgttttgaaa catttccgaa aacttcatcc
    18841 ctatctcgga atcctcaaaa aagtgggtgg ttttctcatt attgtgatgg gattcttggt
    18901 tctgtttgga aatgcttcaa ttttaagtca attatttgaa taaaatggaa aggaatatca
    18961 atatgaaaaa atggcaaaca tgtgttcttg gagcaggttc gctcctttgt ttgacggctt
    19021 gttcaggcaa gtccgtgact agtgaacacc aaacgaaaga tgaaatgaag acggagcaga
    19081 cagctagtaa aacaagcgca gctaaaggga aagaggtggc tgattttgaa ttgatgggag
    19141 tagatggcaa gacctaccgt ttatctgatt acaagggcaa gaaagtctat ctcaaattct
    19201 gggcttcttg gtgttctatc tgtctggcta gtcttccaga tacggatgaa attgctaaag
    19261 aagctggtga tgactatgtg gtcttgacag tagtgtcacc aggacataag ggagagcaat
    19321 ctgaagcgga ctttaagaat tggtataagg gattggatta taaaaatctc ccagttctag
    19381 ttgacccatc aggcaaactt ttggaaactt atggtgtccg ttcttaccca acccaagcct
    19441 ttatagacaa agaaggcaag ctggtcaaaa cacatccagg attcatggaa aaagatgcaa
    19501 ttttgcaaac tttgaaggaa ttagcctagg aggcgtctta tgaatgataa gttaaaaatc
    19561 ttcttgttgc taggagtatt ttttctagcc ataaccggtt tctatgttct attgatacga
    19621 aatgcagggc agacagatgc ctcgcaaatt gaaaaggcgg cagttagcca aggaggaaaa
    19681 gcagtgaaaa aaacagaaat tagtaaagac gcagacttgc acgaaattta tctagctgga
    19741 ggttgtttct ggggagtgga ggaatatttc tcacgcgttc ccggggtgac ggatgccgtt
    19801 tcaggctatg caaatggtag aggagaaaca accaagtacg aattgattaa ccaaacaggt
    19861 catgcagaaa ccgtccatgt cacctatgat gccaagcaaa tttctctcaa ggaaatcctg
    19921 cttcactatt tccgcattat caatccaacc agcaaaaata aacaaggaaa tgatgtgggg
    19981 acccagtacc gtactggtgt ttattacaca gatgacaagg atttggaagt gattaaccaa
    20041 gtctttgatg aggtggctaa gaaatacgat caacctctag cagttgaaaa ggaaaacttg
    20101 aagaattttg tggtggctga ggattaccat caagactatc tcaagaaaaa tccaaatggc
    20161 tactgccata tcaatgttaa tcaggcggcc tatcctgtca ttgatgccag caaatatcca
    20221 aaaccaagtg atgaggaatt gaaaaagacc ctgtcacctg aggagtatgc agttacccag
    20281 gaaaatcaaa cagaacgagc tttctcaaac cgttactggg ataaatttga atccggtatc
    20341 tatgtggata tagcaactgg agaacctctc ttttcatcaa aggacaagtt tgagtctggt
    20401 tgtggctggc ctagttttac ccaacccatc agtccagatg ttgtcaccta caaggaagat
    20461 aagtcctaca atatgacgcg tatggaagtg cggagccgag taggagattc tcaccttggc
    20521 catgtcttta cggatggtcc acaggacaag ggcggcttac gttactgtat caatagcctc
    20581 tctatccgct ttattcccaa agaccaaatg gaagaaaaag gctacgctta tttactagat
    20641 tatgttgatt aatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    20701 gtagggttac tgacttcgtc agttttatct acagcctcaa agctatactt tgagctgact
    20761 tcgtcagttt tatctacagc ctcaaagcta tactttgagc tgacttcgtc agttttatct
    20821 acaacctcaa agctatactt tgagctgact tcgtcagttt tatctacaac ctcaaagcgg
    20881 tactttgaga aacctgtggc tatcttccta gtttactttt tgatttttat tgagtataag
    20941 aggtctttcc taagcagtta gaggagaatt ttgctatact gatactagta agtggtaaag
    21001 gagcagatca tgacctacac aatcttaatc gtagaagatg aatatctggt aagacaaggt
    21061 ttgactaaac tggtcaatgt agcagcctac gatatggaaa tcatcggtca ggctgaaaat
    21121 ggaaggcagg cttgggaatt gatccaaaag caggtgccag atatcatttt aaccgatatc
    21181 aacatgcctc atctaaatgg catccagttg gccagtctgg tacgagaaac ctatcctcag
    21241 gttcatttgg tctttttaac aggttacgat gattttgatt atgccttgtc tgctgtcaaa
    21301 ctaggtgtgg acgactacct gctcaaaccc ttttctcgtc aggatattga ggaaatgttg
    21361 gggaaaatca aacaaaaact agacaaggaa gagaaagaag agcagttaca agatttattg
    21421 actaataggt ttgaaggaaa catggcccag aaaatccagt ctcatctggc tgatagccaa
    21481 tttagtttaa agtctttagc cagtgactta ggttttagtc cgacctatct gagttccttg
    21541 attaagaaag agttgggctt gccttttcag gattatctgg tgagagaacg tgttaaacaa
    21601 gccaagctct tgcttttaac tacagatctg aagatttatg agatcgcaga gaaggttggt
    21661 tttgaagata tgaactattt tacccaacgt tttaagcaga ttgcaggtgt gacacctcgt
    21721 cagtttaaga agggagaaga ccgatgaagc gttcttctct tttagttaga atggttattt
    21781 ccatctttct ggtctttctc attctcctag ctctggttgg aactttctac tatcaatcaa
    21841 gttcttcagc cattgaggcc accattgagg gcaacagcca aacgaccatc agccagacta
    21901 gccactttat tcagtcttat atcaaaaaac tagaaaccac ctcgactggt ttgacccagc
    21961 agacggatgt tctggcctat gctgagaatc ccagtcaaga caaggtcgag ggaatccgag
    22021 atttgttttt gaccatcttg aagtcagata aggacttgaa aactgttgtg ctggtgacca
    22081 aatctggtca ggtcatttct acagatgaca gtgtgcagat gaaaacttcc tctgatatga
    22141 tggctgagga ttggtaccaa aaggctattc atcagggagc tatgcctgtt ttgactccag
    22201 ctcgtaaatc agatagtcag tgggtcattt ctgtcactca agaacttgtt gatgcaaagg
    22261 gagccaatct tggtgtgctt cgtttggata tttcttatga aactctggaa gcctatctca
    22321 atcaactcca gttggggcag cagggctttg ccttcattat caatgaaaac catgaatttg
    22381 tctaccatcc tcaacacaca gtttatagtt cgtctagcaa aatggaggct atgaaaccct
    22441 acatcgagac aggtcagggt tatactcctg gtcacaaatc ctacgtcagt caagagaaga
    22501 ttgcaggaac tgattggacg gtacttggcg tgtcatcatt ggaaaagtta gaccaggttc
    22561 ggagtcagct cttgtggacc ttgcttgggg ccagtgtcac atctcttctt gtctgtctct
    22621 gcttagtgtg gttcagtctt aaacgctgga ttgctccttt gaaggatttg agagaaacca
    22681 tgttggaaat tgcttctggt gctcaaaatc ttcgtgccaa ggaagttggt gcctatgaac
    22741 tgagagaagt aactcgccaa tttaatgcca tgttggatca gattgatcag ttgatggtag
    22801 ctattcgtag ccaggaagaa acgacccgtc agtaccaact tcaagccctt tcgagccaga
    22861 ttaatccaca tttcctctat aacactttgg acaccatcat ctggatggct gaatttcatg
    22921 atagtcagcg agtggtgcag gtgaccaagt ccttggcaac ctatttccgc ttggcgctca
    22981 atcaaggcaa ggacttgatt tgtctctctg acgaaatcaa tcatgtccgc cagtatctct
    23041 ttatccagaa acaacgctat ggagataagc tggaatacga aattaatgaa aatgttgcct
    23101 ttgataattt agtcttaccc aagctggtcc tacaacccct tgtagaaaat gctctttacc
    23161 atggcattaa ggaaaaggaa ggtcagggcc atattaaact ttctgtccag aaacaggatt
    23221 cgggattggt catccgtatt gaggatgatg gcgttggctt ccaagatgct ggtgatagta
    23281 gtcaaagtca actcaaacgt gggggagttg gtcttcaaaa tgtcgatcaa cggctcaaac
    23341 ttcattttgg agccaattac cagatgaaga ttgattctag accccaaaaa gggacgaaag
    23401 ttgaaatata tataaataga atagaaacta gctaactccc agtcaattct gggagtttta
    23461 tgcgtaattg ggcaaacttt ataggttgtc tatcttgcta aaaacaagaa aaaacggtat
    23521 gatagaagag tgacaacaga ggtaacagag atgaacgaga cacagattca aagagaaaca
    23581 cgtcaggtag tggaagatgt tttagaaaag accaatttga agcagggggt cctttttgtt
    23641 ttaggtctat cttctagtga ggtgctaggt ggtcagattg ggaaagaatc cagtcaagag
    23701 attggtgagc tgatagtgga gactatcttg ggtattctag gtagtagagg tatccattta
    23761 gcagttcaag gttgtgagca tgtcaatcgg gctctcgttg ttgaacgtca ggtggcagag
    23821 cagtttgatc tggaaattgt cagtgtccat cctactcttc atgcaggagg ttcggggcag
    23881 ttggcagcct ttaagtttat gcaggatcca gttgaggttg aatttatcaa ggctcatgct
    23941 ggattggata tcggagacac tgcaattggc atgcatgtca agcatgttca ggttccgatt
    24001 cgccctattt tgagagagat tggtcatgcc catgtaacgg cactggctag tcgtccaaaa
    24061 ttaatcggag gtgcgcgtgc gcactatccg caagacgcta ttagaaagtc ttgagaatga
    24121 ataaaggaga taaaagtgtt taaaaaagac cgtttttcaa ttcgtaagat taagggagtt
    24181 gtaggctctg tatttcttgg aagccttttg atggctcctt ctgtagtgga cgcagccacc
    24241 tatcactatg taaataaaga gattatttca caagaagcta aagatttaat tcagacagga
    24301 aagcctgaca ggaatgaagt tgtatatggt ttggtgtatc aaaaagatca gttgcctcaa
    24361 acagggacag aagcatctgt tttgacagct tttggtttgc tgactgttgg gagcttgctt
    24421 ttaatctaca agagaaagaa aattgctagc gtctttctag ttggagctat gggattggta
    24481 gttcttccta gtgcagaggc tgtagaccca gttgcgaccc tagcgctggc tagtcgagag
    24541 ggtgttgttg aaatggatgg ctatcgctat gttggttatc tatcaggtga catcctcaaa
    24601 acgcttggct tggacactgt tttagaagaa acctcagcaa aacctggaga ggtgactgta
    24661 gtcgaagttg agactcctca atcaacaaca aatcaggagc aagctaggac agaaaaccaa
    24721 gtagtagaga cagaggaagc tccaaaagaa gaagcaccta aaacagaaga aagtccaaag
    24781 gaagaaccaa aatcggaggt aaaacctact gacgacaccc ttcctaaagt agaagagggg
    24841 aaagaagatt cagcagaacc agctccagtt gaagaagtag gtggagaagt tgagtcaaaa
    24901 tcagaggaaa aagtagcagt taagccagaa agtcaaccat cagacaaacc agctgaggaa
    24961 tcaaaagttg aacaagcagg tgaaccagtc gcgccaagag aagacgaaaa ggcaccagtc
    25021 gagccagaaa agcaaccaga agctcctgaa gaagagaagg ctgtagagga aacaccgaaa
    25081 caagaagata cacagccaga agtagtagaa acaaaagatg aggctgctaa tcaacctgtt
    25141 gaagaaccaa aagttgaaac gcctgctgta gaaaaacaaa cggaaccaac agaggaacca
    25201 aaagttgaac aagtaggtga accagtcgag ccaagagaag acgaaaaggc accagtctct
    25261 ccagaaaagc aaccagaagc tcctgaagaa gagaagactg cggaagaaac accgaaacaa
    25321 gaagataaaa taaagggtat tggtactaaa gaaccagttg ataaaagtga gttaaataat
    25381 caaattgata aagctagttc agtttctcct actgattatt ctacagcaag ttacaatgct
    25441 cttggacctg ttttagaaac tgcaaaaggt gtctatgctt cagagcctgt aaaacagcct
    25501 gaggtaaata gcgagacaaa agctgaaaaa gttgcagcta atacagatgc taaacaaagt
    25561 gaagtaaatt ctgagactgc aagtcttaaa acagcaattt ctggattaaa tacagataaa
    25621 gttgaactcg aaaatcaact taagattgca cagggaaaaa ctgaaactga tttcagcatg
    25681 gaatcttgga cggttttgag tacagctaaa aataaagctc aggaagtaaa agataacgga
    25741 acagcgaccc aagaacaaat aaacgaagca gagaaaagtt tgaaaacagc ccttgctgac
    25801 ttatctgttg acaaaacagc tttgggaagc gctatcgata cagctaccaa gaaaaataaa
    25861 gagaactata caaatcaaac atgggcagag ttagaaacag ttcttacagc agcaaaatct
    25921 gtaaacacta acgagtctaa acaaagtgaa gttaatgaag ctgttgaaaa attaactgca
    25981 actattgaaa aattggttga attgtctgaa aagccacgtt tgactctatc tattgaaaag
    26041 agagacatag atcgaaaagt tacggtcacg tatactttgg aaaatccagc aaatactcaa
    26101 ataaaatcaa taactgcaac tctgaaaaaa ggagaggaag ttgttaagga ttttgtttta
    26161 acagaagaaa atcttaaaac taatcattta actgctttgt ttgaaaagct agattactac
    26221 aaagaataca ctctatctac ggatatggta tataacagag gaaatgatga tgagacggag
    26281 agtatttcag aagaactaat tcagctgaat cttaagaaac tagaattgaa agatatccag
    26341 acagtctctc tgatgaaatt tgaaaatggt caagaaagtc aggttacaca cttgtctgat
    26401 aaaccgaccg atttgagtaa attatactta aaagttacat catcaacgtc taaggatgct
    26461 gtgttagccg ttagctctat agaagaagag attgttgaaa ataaaaaaat ctttaaaatt
    26521 catgcagata caccagaatt agtagttcgt aagaaagatg gcagtctttc taagggattt
    26581 gactattaca tggagagagt tatccctcat gatggtgata tttattatga ttttaaagac
    26641 ttgatttcag ctatgacatc taatcctaca ggtacgttta ttttagggag agatatttcc
    26701 tcgcgtaatg taaaaccgga tggaaatgga aaatcttata tcaaaggtga atttaaagga
    26761 aaactacttg gtacaaatga taatgttaga cactcgatct ttgacttaga atatccattg
    26821 tttgatacta taaaatcagg agtcgtgaaa gatattgatt tcaagcatgt caatatggta
    26881 ttcccagata gcaatcaagg agataacgta gcaacaattg caagagtaat caaagataag
    26941 acaaaaattg agaatgttaa tgttgaaggt tatctcgagg gtcgagatca tgtagctggt
    27001 ttagttaata atcttgaagg taattccgaa attgaaaata tatcctttac aggaaagatt
    27061 aagtctaaag gtggtaattc tattacagca ggtattgcag gtagaaatat cttatctcgt
    27121 gttaaacgtg cctatgtaaa tgcaaatatt gaagtccttg gttcaacgaa ttcgagtatg
    27181 cttgttgcag taaatggtac aacattgaat gctagtggag gttggggagc ctggggaaga
    27241 cttactgagt ccgttgctaa agggacgtta gaaattaaac gcagtggaca agctggtgga
    27301 gttactgcaa cagtctggcc ttatggagca attgataagg ttgtcagcta tgcaaaagtt
    27361 accaaaggaa aagaattatt tgggtcagat ggtgatttaa ataataattg gtttatgcaa
    27421 aaaattaata atatttttgg tgttcaaggt atcagctcag gtgactcagg gaatgattct
    27481 aagtttaagc gtatttccga ggaagaagca aagcaaaagg ttgcctctta taatattaca
    27541 gctcccaact tgatgagcga ctcaagtctt ttggtagaca gactcaatga aagttggaaa
    27601 aatactgatc aatttgaaag tatacaggat tatcaatccc aaaaccaatt aatttaccag
    27661 aacttgacta aatttactcc ttattacaat aaagaattta ttgttcatga aggaaatgct
    27721 ctcactcctg aacaggaaat attgaagact aagaaaatca aatcgattgt agggttgaaa
    27781 ggaacagagt tcgttgtaga tggcagtgat attgatacta tcatgcttca ttttgaggat
    27841 ggtagtcaga agcgatataa ggtaacctct actggtaagt tttcgataac taatttaccg
    27901 gaatatcagg ttgaagattt aaatgtggtg tatacatcag aacatatagt acatccacta
    27961 gattcgtcac tgataaataa ccttgttgaa gaattgaaaa aagtagaatt gtatacagag
    28021 tctacttacc aagttctagg tattgataaa gataatgcta acaaattgaa tagaactaag
    28081 agattattct tagatgagtc attagatgct gttaaaacac aattgcctac ctttgtaaaa
    28141 acaatgtttg aaaatgagtg gttgcacatc aatggagaat ctagtggagc tgtcgctgct
    28201 ttacgacaaa aaatcatgga taataagacg gctatattgc ttgctttgac ttatatcaat
    28261 cgttattatg atgttaaatt ctcagactat aatattaaaa aactgatgct ctttaaacca
    28321 actttccatg gtgaaaagat tgatctatta gatcgattaa tccgactagg atcatctgga
    28381 gaaaatagat taaaaggttc agaaaatgca gaaacgttca agcagttatt tgctagcgaa
    28441 acgaagcaga aggatttggt gacttattta gactacaatc gctctttgtt gactaattat
    28501 caaacaacag gggaatggtt taaagaaacg actaaggatt atattcaatt tgaggaacgt
    28561 ccatccttag tagaggagat taaagatgcc aaatatcgag tttacgataa tttaaccgca
    28621 ccgtattatc aaggatatat cctacctctc ttaacgttga agaatactca tttagcaatt
    28681 ttatcgaact atagtactat gacatttgtc agccgtgaaa aacgccctaa ttggaaaaat
    28741 gaagattttg ataagtgggt gaaatatgta gcaactgctc atagaaacca tgttgatact
    28801 tggtataaga ttttacctga taatatcaaa ggtaaaatgg ttaaagagaa tgttactgct
    28861 gtttgggaag gattgagcat cccaggaagt gaatgggtag accagaatgc tgtagataga
    28921 aaaggaagag attacgcccc agctcgagaa ttctttaatc ttgtaggtgg tcctatggga
    28981 ggttggtatg cttaccatgg ttatggtgcg catgctggag gaagaaatcg ggttaattat
    29041 gaggtgtttg atgtattaag tgagtatggt atatcggtct ttactcatga attgactcac
    29101 gttaatgata cttggattta cttaggaggg tatggtagac gtgaaaatat gggacctgaa
    29161 gcttatgctc agggattatt ccagtctcct gttccaggtc agccgggttg gggggcgctt
    29221 ggtctcaata tggcatttga aagaaaaaat gatggtgatc taatttataa tgcctcccca
    29281 actcaatttg aaaataggaa agagttagat agttatatga aaaattataa cgatactctc
    29341 atgatggtgg actacttgga aggagatgca gttatctcta aaggtaaaga agctattact
    29401 aaatggttta aaaaagttga acctaaggtt gttagtcaaa cagctcagta tgatacggtt
    29461 cgtcagttga ctgctgaaga gaaagaaaaa ctttctgttt ctagtgttga tgatttagtt
    29521 gatcaaggat taatgtcaga cagagctgta ggaaataata cctataatcc agctgatttt
    29581 gaaacaagtt atattgcgat agattatatg actggtattt atggtggagg aaagaatagt
    29641 gtaggttcac caggtgcctt gatgtttaaa cataatactt tccgtatgtg gggctactat
    29701 ggttttgaag aaggtgttct aggatatgct tctaataaat ttaagcaagc atctagagat
    29761 gaaggtcatg ctggacttag tgataacttt attatttcta agatttccaa aggggaattt
    29821 ttaactatgg aagcatttaa aaagggatat tttaagaaag tagtagaaga gttaaaaact
    29881 aaaggtattc gtcctgttac tatcaatcaa aaaacatata gcacctttga agaattgcaa
    29941 gaaggattta agcaggctgt tgaaagagat ttgaagaaaa atcagttaga tgagagggaa
    30001 acaagaaact tcaaattcca agttttcaga caacttcttc aacaaacaga tagctttaaa
    30061 acttctatct ttagataatc gaaatctctc atctgctttg cggatgaggg ttttcttatt
    30121 ttatgctata cttaaggtat gcatagaaaa acagtgattg attttaggac tttaggggag
    30181 agatatacct ttacccagcc tattaaagag ttgaaaacga gaaatgtaga agaagtggca
    30241 gatttgctgg cacaagtgga aagctaccaa gagcaaggtt attatgtggt ggggtatgtc
    30301 agctacgagg ctgcacctgc ttttgaggaa aaattagcag ttcacaagga tcccctactg
    30361 ggagagtacc tgctttattt tactgttcat gatagcgtag aaacttcccc tattcctctg
    30421 acttatgagg atattgattt gccctcaaat tggcaggaag taacgtctgc agcagactat
    30481 gaaaaggcca ttgcccagat acaccatcac ttgaggcagg gagacaccta tcaggtcaac
    30541 tacaccgtcc aactcaagca aaagttaagt gccaatcctt ttgccatcta caatcgtatg
    30601 gtggtagagc aggaggcggg ctacaatgcc tatgtggaac atgacgagat ggcagtgatt
    30661 tccatgagcc cagagctctt ttttgagcaa aatgatcgcg agttgacaac acgaccaatg
    30721 aaggggacga ctcagcgtgg ggtaactgac caagaagatc ttgaacaggc cagttggttg
    30781 gaacaggatc ccaaaaatcg ctctgaaaat atgatgattg tggacctctt gcgcaatgat
    30841 atgaaccgta tttctgaagt tgggagcgag cacgtggagc gtctgtgcca ggtagagcag
    30901 tattcaactg tttggcagat gacttcgacc atcaagagtc agttgcgaga ggatgtggac
    30961 cttgttgaaa tcttccgctc actctttcct tgtggttcca taacgggtgc accgaaaatt
    31021 gcgacaatgg agattatcaa gaacttggag cctcaaccgc gtggagtcta ctgtggaacg
    31081 attggtctct tgcttccaaa tggacgacgg atttttaatg tggccattcg taccattcaa
    31141 cttcacaaag gtcaagccat ttatggagtt ggcggaggga ttacttggga tagcacatgg
    31201 gaatctgaat accgagaggt tcatcaaaag gcagcagttc tttatcgtaa acaagctcgc
    31261 ttccaactga ttacgacagg ggaaatcagc cagaagaacc tgctgtttga agatcaacat
    31321 ctggaaagac tgagaaaagc tagtcgttat tttgcctttc cttttgatgc agaagacttg
    31381 ggacacaaga ttgaggaaga gtgtcaggat tgtgaagcta atcaagatta ccgcttgcga
    31441 atcagcctta gcaaatctgg agagatagaa gtcaatcgtc aagtattaac ccctctcagt
    31501 acaagctttt gtcaggccca agtctgcctt caggaagctg ctttgaatca atcctttacc
    31561 tactttaaaa ccactcaccg accgcatttg agcctaggag aacaagagaa gatttaccac
    31621 aataagtcag gagaactgct tgaaacctct ataggaaatt tggttctgaa aatcgctgga
    31681 aaactctaca caccgcctat ccgacttgga atcttgccag gaatttaccg tcagcatttg
    31741 ctagaaacag gacaggtaga agagaaagtc ttgaccttgg cagatttaac ccaagcagaa
    31801 gctatttacg gctgtaatgc agtgagaggc ttgtatgaac taagccttga ggagaactag
    31861 atgaaattga tatttttgca tgggttaggg cagtcagcag agtcttggaa agaagttcgg
    31921 aatctactga cagattatcc ttctgaggct atcgagttat ttccttctgg agttagtaac
    31981 tatcaacaag ctaaagagcg agtttatcag cacctagctc aagagacaga accttttgtt
    32041 ttgattggat tgtccttagg tgctgccctg acactagaac tttccagtta cgatttacca
    32101 aatcttcgag ctttgattct gtcaggatgc ccgcttaaat tagcagggaa tatcctattt
    32161 tatcttcagt tgctgatttt taaactactt cccaaaagag tatttgaaaa acagggagca
    32221 gacaagactc ttatggtcgg agtttctgag gaattgaaga cacttgattt aacggatata
    32281 gcagggactt gctcctatcc aaccttacta atttgtggca gcaaagataa accgaatctt
    32341 agttttatga aagctctcca tagactgtta acagattcgc agtttcagat cattcctgat
    32401 ggccctcatg tcttgaataa ggcaaaacca aaggagtttg tagaaaagac cagaagtttc
    32461 cttgaattgc tgaaataagt ttgataaaat aatattgaaa tcgatatcat aattatggga
    32521 gaaagaaatg aataaacgtc tatttttaaa aatgagtctg gtgacgttgc caattttagc
    32581 cttgttttca caaccagttt tggcggaaga aaacatccat ttttcgagct gtaaggaagc
    32641 ttgggcgaat ggctattcgg atattcacga gagagaacct ggttattctg ccaagttaga
    32701 ccgtgatcat gatggtgtgg cttgcgaatt gaaaaatgct cctaagggtg cttttaaagc
    32761 aaaacagtca acggctattc aaatcaacac aagttcagca acaacaagtg gttgggttaa
    32821 gcaggacggc gcttggtact actttgatgg aaatggaaat ctagtgaaaa atgcatggca
    32881 gggaagctat tacctgaaag ctgatggtaa aatggcacag agtgaatgga tttatgactc
    32941 ttcttatcaa gcttggtatt atttgaaatc agatggttct tatgcaaaaa atgcatggca
    33001 aggagcttat taccttaaat caaacggtaa aatggcacaa ggtgagtggg tttatgattc
    33061 ttcttaccaa gcatggtatt acttgaaatc agatggttca tatgctcgca atgcatggca
    33121 aggaaactac tatttgaaat cagatggtaa aatggctaaa ggtgaatggg tttatgatgc
    33181 cacctatcaa gcttggtatt atttgacatc agatggttct tatgcttaca gtacatggca
    33241 aggaaattac tatctaaaat cggatggtaa aatggctgtc aatgaatggg ttgatggtgg
    33301 acgttattat gttggcgctg acggagtttg gaaggaaggt caagcaagta cagtttcttc
    33361 tagtaatgat agcaatagtg aatattctgc tgctttagga aaggcaaaaa gttataattc
    33421 gttattccac atgtcaaaaa aacgtatgta tagacaatta acttctgatt ttgataaatt
    33481 ttcaaatgat gcagctcaat atgccattga tcatttagat gattaacaga tactggtagg
    33541 cgaaaaaatt ccttataatt catttacgca aacctttgca taagtgaatg gattttgata
    33601 tactagtact gtaagcattt tcaattacta cacaatgaaa aaggagaata tgatgagtca
    33661 aaagattatt gggattgacc ttggtggaac ttctatcaaa tttgcaatct taacaacagc
    33721 aggagaaatc caaggaaaat ggtcaatcaa gaccaacatt ttggatgagg gaagtcatat
    33781 cgttgatgat atgattgagt ctattcaaca tcgtttggac ttgcttggat tggcagcagc
    33841 ggacttccaa ggcattggaa tgggatcacc aggtgtggtt gaccgtgaca aagggactgt
    33901 tatcggtgcc tacaacttga actggaaaac ccttcaacca atcaaacaaa agattgaaaa
    33961 agctttgggc attccatttt tcatcgataa tgatgccaac gtagcagctc ttggtgagcg
    34021 ctggatgggt gctggagata accaaccaga cgttgtcttt atgacactcg gtactggtgt
    34081 tggtggtggt attgtcgcag aaggcaaatt gcttcatggt gttgctggtg cagcaggtga
    34141 acttggtcat atcactgttg actttgacca accaatctca tgtacttgtg gtaaaaaagg
    34201 ctgccttgag acagttgctt cagcaacagg gattgtcaac ttgactcgtc gctatgccga
    34261 tgaatacgaa ggcgatgcag ccttgaaacg cttgattgat aacggagaag aagtaactgc
    34321 taagactgtc tttgatctcg caaaagaagg agacgacctt gctttgattg tttatcgtaa
    34381 cttctcacgt tacttgggaa tcgcttgtgc taacattggt tcaatcctaa acccatcaac
    34441 aatcgtcatc ggtggtggtg tgtcagctgc gggagaattc cttctacaag gtgttcaaaa
    34501 agtttacgat gaaaatagtt tcccacaagt acgcacatct actaaattag ctcttgcaac
    34561 tctaggaaat gacgctggag ttatcggagc agcatcactt gtattgcaat aagataatga
    34621 gagaggaaaa tgctaaccta gagttagtaa tgttcctctt ttatttttta tgctatacta
    34681 gttaggacaa tgaatgaggt gagagtaaat gacaaaagca gatacgattt ttaaagagaa
    34741 tattgaacgc attctaaagg aaggtgtttt ctcagagcag gctcgtccta agtacaagga
    34801 tgggactgtt gctaattcca agtatgtaac tggtgccttt tccgagtacg acttatctaa
    34861 aggagaattt cctatcacaa ccttgcgtcc cattgccatc aaatccgcca tcaaagaagt
    34921 tctctggatt taccaagacc agtcaaatag cttagaagtg cttaatgaca agtacaatgt
    34981 tcactactgg aatgactggg aagttggaga cacgggaacc attggtgagc gctatggtgc
    35041 cgttgttaag aaacacgaca ttatcaataa gcttctcaaa cagttggaaa ccaatccttg
    35101 gaaccgccgc aatattattt cgctctggga ttaccaagct ttcgaagaaa cagatgggct
    35161 gctcccgtgc gcctttcaga ccatgtttga tgtccgccgt atagatggag aaatctatct
    35221 ggatgcgacc ttgacccagc gctcgaatga tatgctggtg gcccaccaca tcaacgctat
    35281 gcagtatgtg gctttgcaga tgatgattgc caaacatttt ggctggaagg ttgggaagtt
    35341 cttctacttc atcaacaacc tccatatcta tgataatcaa tttgaacaag ctcaggaatt
    35401 gctccgtcgg gagccgtcaa actgccaacc acgcttggtt ttaaatgttc ctgatgggac
    35461 taatttcttt gatatcaaag cagaagattt tgagttggtg gattatgacc ctgttaagcc
    35521 acagttgaag tttgacctag ctatttaaaa gaatagaaaa aagaagttga gaataatccc
    35581 aacttctttt gtttcttaac gtgatacgcg gcgacgagct gcttttttac ggttttcttc
    35641 gatgaaagct gctttttgct cttctggttc gattactttc tttttaaatg cgtatactgc
    35701 acctgcaacg gcagcgacag ttcctgcgac acctgttaca agacctttag cgaatccttt
    35761 agccatgagt cttcctcctt tatattctca atcagccagc ctcctcaaga ggtcacattt
    35821 ttctgactga cctttttgtg ttataataat agtaacgaaa aaatgggaat ttttcaagga
    35881 aaaaagatga aaacaaaaat aattgtgatt gttggaccga ctgctgttgg aaagacggct
    35941 ctagctattg aagttgcaaa gcgttttaat ggcgaagtgg ttagtggaga tagccagcaa
    36001 gtctatcgag gacttgatat tgggacggcc aaggctagtc cagaagagca ggcagctgtt
    36061 cctcatcatt taatcgatgt tagagagata accgagtctt actcggcttt tgattttgtt
    36121 tcagaagcta agatgactat tgagggtatt cacaaccgtg gcaagctagc cattatcgcc
    36181 ggtgggactg gactttatat ccagagcttg ctagaaggtt accacctagg tggggagact
    36241 cctcatgagg agattttagc ttatcgagct agtttggagc catattcaga tgaggaatta
    36301 gcccatttgg tggatcaagc aggccttgag attccccagt ttaatcgtcg tcgtgctatg
    36361 cgtgccttag aaattgccca ttttggtcag gatttggaaa atcaagagac cttgtatgaa
    36421 ccgctgatta tctgcttgga tgatgaacgt agtcaacttt atgagcgtat caaccaccga
    36481 gtggatttga tgtttgaggc tgggcttttg gatgaggcca agtggctgtt tgaccattcc
    36541 cctaatgtac aggctgctaa aggaattggc tataaggaac tctttcctta tttccgtgga
    36601 gagcagacct tggaggaagc tagtgagagt ctcaaacagg cgacccgtcg ttttgccaag
    36661 cgtcagctga cctggttccg taatcgcatg caggtcacct tttatcagat tggagaatct
    36721 ggtgtacaag accgcatttt aagccagata gaggagtttt tagatgattg aaacggagaa
    36781 aaaagaggag cgagtcctgc tgattggtgt ggaattgcag ggtatggaca gttttgacct
    36841 ctccatggaa gaattggcta gtttagcgaa aacggcaggg gcagtcgttg tagatagcta
    36901 cagacaaaaa cgtgaaaaat atgattccaa gaccttcgtc ggctctggta agttggaaga
    36961 gattgcgctt atggtggatg cagaagaaat cactactgtc atcgtcaaca accgtctgac
    37021 cccaaggcag aatgtcaatc tagaggaagt tctcggtgtt aaggtcattg accgtatgca
    37081 gttgattttg gatatctttg ccatgcgggc tcgaagccat gaagggaagc tccaagtcca
    37141 cctagcccaa ctcaaatacc ttttgcctcg cttggttggt caggggatta tgctcagccg
    37201 tcaggcaggg ggaattggtt cccgtggtcc tggtgaaagc cagctggagc tgaaccgtcg
    37261 tagcgttcgc aatcaaatca cggatattga gcgccagctc aaggtggttg agaaaaatcg
    37321 ggcgactgtc agagaaaaac gtttggagtc tagcactttt aagattggtt tgattggtta
    37381 tactaatgct gggaaatcaa ctatcatgaa catcttgacc agtaagaccc agtatgaagc
    37441 agatgagctc tttgcgactc tggatgcgac aaccaagagt attcatctgg gaggcaatct
    37501 ccaagtaact ttgacagata ccgttggctt tatccaagat ttgccgacag agttggtgtc
    37561 cagtttcaag tcaaccttgg aagaaagcaa gcatgtggac cttctggttc atgttatcga
    37621 tgctagcaat ccttaccacg aggagcatga aaaaacggtt ctctccatca tgaaagacct
    37681 ggacatggaa gatattcctc acttgacgct ttataataaa gcggatttgg tggaggattt
    37741 cacgcctacc caaacgccat ataccctcat ttctgccaag tctgaggaca gtcgtgaaaa
    37801 cttgcaagca ttattgctag ataagattaa ggaaattttt gaagcattta ccctgcgagt
    37861 gcctttttca aagtcctaca agattcatga tttagagagt gttgcaattc tggaagaacg
    37921 tgattatcag gaagacggcg aagtgattac aggctacatt tccgagaaaa ataaatggag
    37981 gttagaagaa ttttatgact gatattaaaa ctttggctct aaagtatgga ggttatacaa
    38041 gtctggacaa ggtctatctg gatcagcttc tagctggtaa aacagagcag gagcagttaa
    38101 cacttattac acctccgcca agtgttgtta atgcctactt tgcagaactc tatcagaaaa
    38161 aaagtcctca ggctgcgacg gattattttg cagaactcag tcaggaactg aatctttaca
    38221 atactgagcc aagtttcacc ctagaaaata agccttttat tcggcttaat ctgtctggta
    38281 aatcctttgg tttttgttat gagagtgacg gctttggtcg gattttctct gaaaatgagg
    38341 agaaaatctc ggatgacttg ctctttgaaa ttgcgcaaat tttctcccat caattagtct
    38401 ttgaagagtc tggtaagatt tacatgaagc ctgtcaagga cgaggaagtt gtcagcctag
    38461 aaagtctcac agctttgact gatttggaaa gattggctga tggtcgaaaa cgtctcaaag
    38521 gctacagcca agaggattta ttgcaagaag ctgctgcttt ttctggcaaa cgctatttcc
    38581 gatcggaaaa ccgcacagcc atgttatata ttgattaatt agaaagtatc gaatggatat
    38641 tcaattttta ggaacggggg ctggtcagcc ctctaaagcc cgcaacgttt caagtctcgc
    38701 cctgaaactt ttggacgaga ttaacgaagt ttggctcttt gactgtggag aaggtacgca
    38761 aaatcgcatt ctggaaacca caattcgacc acgtaaggtc agcaaaatct ttattactca
    38821 tctgcatgga gaccacattt ttggtttgcc aggtttcctt tctagccgtg cctttcaggc
    38881 caatgaagag cagacagatt tggaaatcta cggacctcaa ggaatcaagt catttgtctt
    38941 aaccagcctt cgtgtgtcag gttctcgtct gccctaccgc attcatttcc atgagtttga
    39001 ccaagattct ctgggtaaaa ttcttgaaac cgataaattc actgtgtatg cagaggagct
    39061 ggaccacact attttctgtg ttggctatcg tgtcatgcaa aaggatctag aagggacgct
    39121 ggatgctgaa aaactcaagg ctgctggtgt tccgttcggc ccgctttttg gtaaaatcaa
    39181 aaacggccag gatcttgttt tggaagacgg aactgaaatc aaggcagcag actatatctc
    39241 agcgccacgt ccaggtaaga ttatcactat tttaggagac actcgaaaaa cggatgccag
    39301 tgtgcgtctg gctgtcaatg cagatgtcct agttcatgag tccacttatg gcaagggtga
    39361 tgaaaaaatt gctcgtaacc atggtcactc aactaatatg caagctgcac aagtagcggt
    39421 agaagcaggt gccaaacgcc tcctactcaa ccatatcagt gcccgtttcc tctcaaaaga
    39481 tataagcaaa ctcaagaagg acgctgccac aatttttgaa aatgtccatg tggtcaaaga
    39541 cttggaagaa gtggaaatct agcagtcaca gaaaggataa gtatgcctac tattctcatt
    39601 accggagcta gcggtggtct agctcaagaa atggtcaaac tcctgcccaa tgaccaactc
    39661 atcttgcttg gtagaaataa ggaaaaatta gcccaactct acggaaatta ttcccatgca
    39721 gaattgattg aaattgatat taccgacgat tcagccctag aagctctggt aactgatctt
    39781 tatctccgct atggcaagat tgatgtcttg attaacaacg ctggttacgg gatttttgag
    39841 ggatttgacc agattgctga taaagatatt caccagatgt ttgaggtcaa tacctttgcc
    39901 ctgatgaatc tgtctcgtca ccttgcggct cgtatgaagg aaagcagcaa agggcatatc
    39961 atcaacatcg tcagcatggc aggtctaata gctactggca agtctagtct ttactcagcg
    40021 accaagtttg cggctattgg tttttcaaat gctctgcgac tcgaacttat gccctatgga
    40081 gtctatgtga caacagtcaa tccaggacca atccgtacag gatttttcga ccaagccgac
    40141 ccagatggaa cttatcttaa atcggttgac cgcttcctgc tagaaccaga tgcagtggct
    40201 aaaaagattg tcaagattat aggaaaaaac aaacgagaac tcaatctccc gattttgttg
    40261 aacctagctc ataagtttta taccctcttt cctaagctag ctgataagtt ggcaggggaa
    40321 acttttaatt ataagtaaaa agaaccaatg tgcaggttgt tgctagccta catattggtt
    40381 cttatcattt ctcaactatc aaactgaact tcttctagga ggtagtctat aaagcgttcg
    40441 cccatcttag ataggctggt tttctcatgc tggatataga ccagctcaat cgggtcatca
    40501 atatccagtg ggatagaaac gatattgtct ccgtttaggt tgctgttcaa aatccctgtc
    40561 gcaatggtat aaccatccaa accaatcaag agattaaaga gggtggcacg gtcactgacc
    40621 acaatggatt tcttgtggtg ttcttgagaa agaatctctt ctgaaaagta gaaggagttg
    40681 tgcgtccctt ggtcatagct gaggtaaggg aaattctcca aatcagacag tttcaccttg
    40741 tctttctttg ccagagggtt ggtcttgctg acaaagatat gtggttgcgc tgtgaagaga
    40801 tggtgggcta gcaggtgatt gtcatccagc atcttggtta aaacatcacg gttgtaactg
    40861 tttaagaaga ggaccccgac ctcactgcgg aagttcttga cgtcgtcgat aatctcccaa
    40921 gtccgagttt cacgaaggaa gagttcgtat ttctccatat cgcttttctt gagcaaagag
    40981 acaaaggcat tgaccacaaa ggcatagtgt tgagacgaaa cgctaaatag ttcgcggtgg
    41041 gcgacaggat ttttatagcg ttcctccaga agctgggtct gctcgacaac ctgacgggca
    41101 taggagagaa actccatccc atcacgggtc aaggtgattc ccttgggatt gcggataaag
    41161 atctcaatgc ccatttcatt ttccaaatct cgcactgcat tggagagact tggctgagtg
    41221 ataaagagtt gcttggctgc ctcattcatg gagccagttt cgacgatttt gataatataa
    41281 tgtaattgtt gaattctcat gtttttattg taccatactt gccttagaat cgctaaagaa
    41341 gatgggaaaa taaggagcat tgtgtgagtc tcttcttgaa aaaaacacaa aattttgcta
    41401 gaatgagtct tatgaaaaca ttctatgatg tgcagcaatt cctcaaacga tttggtatta
    41461 ttgtttacat gggaaaacgc ttatatgata ttgaactgat gaagttggaa ctatctcgga
    41521 tttacgatgc agggttgatg gataaattag actatctaga ggcagaagca gttcttcgca
    41581 gagagcacaa ggtagaattg gattatattg agaaaaatgg agaaaagaac taatggttac
    41641 ttggattttg tgggcactta tactagcaat gttggcgtgg atgggcttta actatcttcg
    41701 tattcgccgt gcggctaaaa ttgtggacaa tgaggagttt gaagccttga ttcgtacggg
    41761 tcaattgatt gatttgcgcg acccagcaga attccacaga aaacatatcc ttggtgcacg
    41821 caatattcct tcaagtcagt tgaaaactag tcttgcagcc cttcgtaaag ataaacctgt
    41881 ccttctctac gaaaaccaac gtgcgcaacg agttacaaat gcagctcttt acttgaaaaa
    41941 acaaggtttt tctgagattt atatcctttc ttatggcttg gattcttgga aagggaaagt
    42001 gaagactagc taaccttatt tccaaattag ttgaatgata ggatgaagct attgttttat
    42061 agtataatta atttgtataa aatttaagga gttcttagaa catgaaagaa aagaagaaaa
    42121 tccacttttt gtgggtatct tgtcgattat tcttggtttg ttatttccaa ttgtaggcct
    42181 gattttgggt atcataggat tggtcttggc tatttcatac caaaaagagt cacaattaga
    42241 ctataaaata gaaaagattc ttaatatctt aggaattgtg atttctgtag ttaactggat
    42301 tgtagcaatc gccttaattt ttcggtaaat aaaagaaaaa agctttagtt ttaaagcttt
    42361 ttttatttta tcgactcatc tctaaatagt ttttaatgat ttgtaactct ttttggttca
    42421 aagggcggta gttaccttct gctaaatctg ggttcaatgt gaagtcccca aattggattc
    42481 tcttgaggct agtcacctta acaccaaccg agaggaacat tttcttgatt tgatgaaatt
    42541 ttccttctga aatggtgata gaggcttgac tgatggaggg acttgcagat agaatctcta
    42601 gttttgcggg tttacagaca gtaccatcta aaaagacaat tcccttttga aaggcttgga
    42661 tatggtcagg tgttagaagt ccattaacct caacttgata agtcttatcg acatgatatt
    42721 ggggatggag gagttggaag cccaagggac cgttatcggt caagagaagg agtcctgttg
    42781 tatctcggtc cagtcggccg acggcataga gcttgtcaga ctggatgtca gatggaagca
    42841 ggtccatgac ggtcggaagt tccttgtctt tgttggctgt aacgacacca gcaggtttat
    42901 gaagcataag ataggtgtgt tcatagcctt gaatgattcg atcctgaaaa aggagttctt
    42961 gtagtcctgt atcgatattt tgagctaggg agcgggctgg gcaaccatcg actagaattt
    43021 cccctctgag gagtgcttgt ttcatggcct ttcggctgat tttttcttga gctaataaat
    43081 tatctaaacg catactgtgc ctatcttatc ataagtcgct tgctttgaaa aggcttgacg
    43141 tgaaaagaaa agcggagtga aaacatttac acttgcttga gttatgttat ttatttgaaa
    43201 ttatggtata atcgttcagt tagaaaataa attttgaata ttatagagga aatcatgaca
    43261 aaattaagag aagatatccg taacattgcg attatcgccc acgttgacca cggtaaaaca
    43321 accctcgttg acgaattatt gaaacaatca gaaacgcttg atgcacgtac tgaattggca
    43381 gagcgtgcta tggactcaaa cgatatcgaa aaagagcgtg ggattaccat ccttgctaaa
    43441 aatactgccg ttgcttacaa cggaactcgt atcaacatta tggacacacc aggacacgcg
    43501 gactttggtg gagaagttga gcgtatcatg aaaatggttg acggtgttgt cttggtcgta
    43561 gatgcctatg aaggaaccat gccacaaact cgtttcgtat tgaaaaaagc cttggaacaa
    43621 gaccttgtcc caatcgtggt tgttaacaaa atcgataagc catcagctcg tccagtagaa
    43681 gtagtggatg aagtcttgga acttttcatc gagcttggtg cagatgacga ccagcttgat
    43741 ttcccagtgg tttatgcttc agcgatcaac ggaacttctt cattgtcaga tgatccagct
    43801 gaccaagaag cgactatggc accaatcttt gacacgatta tcgaccatat cccagctcca
    43861 gtagataact cagatgagcc tttgcagttc caagtgtcgc ttttggacta caatgacttc
    43921 gttggacgta tcggtatcgg tcgtgtcttc cgtggtacag ttaaggttgg ggaccaagtt
    43981 accctttcta aacttgacgg tacaactaaa aacttccgtg ttacaaaact cttcggtttc
    44041 tttggtttgg aacgtcgtga aatccaagaa gccaaagcgg gtgacttgat tgccgtttca
    44101 ggtatggaag acatctttgt cggtgaaacc atcactccga cagatgcagt agaagctctt
    44161 ccaatcctac acatcgatga gccaactctt caaatgactt tcttggtcaa caactcacca
    44221 tttgctggta aagaaggtaa atgggtaacc tctcgtaagg tggaagaacg cttgcaggca
    44281 gaattgcaaa cagacgtttc ccttcgtgtt gacccaactg attcaccaga taaatggact
    44341 gtttcaggac gtggagaatt gcacttgtca atccttatcg aaacaatgcg tcgtgagggc
    44401 tatgaacttc aagtatctcg tccagaagtt atcgtaaaag aaatcgacgg tgttaaatgt
    44461 gaaccatttg aacgtgtaca aatcgacact ccagaagaat accaagggtc tgttatccaa
    44521 agcctttctg aacgtaaagg tgaaatgttg gatatgattt caactggtaa tggtcaaact
    44581 cgtttggtct tccttgttcc agcgcgtggt ttgattggat actcaactga gttcttgtca
    44641 atgactcgtg gttacggtat catgaaccat accttcgacc aatacttgcc attgattcca
    44701 ggggaaattg gtggacgtca ccgtggtgcc cttgtttcta tcgatgctgg taaggctaca
    44761 acttactcaa tcatgtctat cgaagaacgt ggtacgatct ttgtcaaccc aggtactgag
    44821 gtttatgaag gaatgatcat cggtgaaaac tctcgtgaaa atgacttgac agttaacatc
    44881 acgaaggcaa aacaaatgac caacgttcgt tcagctacta aggaccaaac agctgttatc
    44941 aagacgcctc gtatcttgac acttgaagag tctcttgagt tcttgaacga cgatgagtac
    45001 atggaagtaa cgcctgagtc tatccgtttg cgtaaacaaa tccttaacaa agcagagcgt
    45061 gagaaagcta acaagaagaa aaaatcagct gaataagagc tagaaagaga gaaagatggt
    45121 ctatttagtc ctaggaattt tactgctcct actctatgta tttgcgacac cagaaagcat
    45181 taaagggact gtcaatatcg tcgctatggt atgtatttta gtggcactct tgattttatt
    45241 ggttctatct tttctgaaaa tttttcaatt accaacagaa atattcctag caatagccat
    45301 gttgatccta gcttacttta gtgttagaga catcacactc atgccagtca aaaaaagtaa
    45361 aagaagataa aaaagagagt ttcggctctc tttttgctag gaattttaca atagtttgaa
    45421 ttgcttttta gttaacacca tctcttttac ttgtatagta tgaatgggaa aaacttgaat
    45481 aaaattcgtt aatggcatct attttatatt tggttagtac tggttgcata ttattttgaa
    45541 ataaaactac tatataatat tattcataga gataatatag taaaacatct aaaaaattcg
    45601 attttttcct tgacaacaaa taataaaaat gttattctta tcacataaga aagcgatttc
    45661 aacaaaagag agaggaggat ttattttgtt gcattgttgc tcaaggtgtg atttttttga
    45721 aagaaaaaat aaaatgaaaa cgaaaaaaca tagattactt gctctagctc ttatttcaaa
    45781 ttttacatta ttgggagctg catcagctgc tgtacaatat ccagatggag gagtatggac
    45841 atatggagaa ggttcaggag gtggttaggc tttttcaaat tactatcatg gtaaaaaata
    45901 tcattattca tccatcgtga gcagatggga tggtcattct gataaaggag aagctcctgc
    45961 tggaaaaacc tcctatgcat ggatttggac taaatgggga gaacaagtag cattttactg
    46021 tgattatgac taatcgttca ttgatttaaa tcgttcccct tgtaagaaat tacaggggga
    46081 attttgttta caaggagtct actatgaaga aactattcat attattatca actttttttc
    46141 tcagcttctt ccttgcttgg attattgtct tacgtgcgcc acaatattta tatgcaagct
    46201 atgattccgt ttctttactt cgtgtcaaaa aagatactca ggaaccgacg cgtgaggtat
    46261 ttgaacagga attggagaat tttgcaaact cagaacagag tttaatagct agaagaattg
    46321 tagagccgag taaggatggg acgactcact ttacttatgc aacttatggt cagggaactt
    46381 taccaaaaga attccaagaa gctagccaag aaagtcgtga acgtagtgat ccgctaaata
    46441 gttatctcct tttgtcaggc tccttgacga aagaaaagct tgccgataaa ttaggagatt
    46501 tgggttataa agcaagtgct gaccgaaaga taccgcccta ttttcttgct tttcgaatat
    46561 tactaaatcc ccttatttta attagtttag caatatttgg tttatctttc tttgctttag
    46621 tgattatcac tcggattaag gaaatgagag cagcaggtat aaaactcttt tctggtcaga
    46681 ctctcttatc catcatgggg cattctttat ctactgatat caaatggctc cttctatcag
    46741 ccctcctttc cttcctaggt gggggagtcg ttctttttag tcaaggtttg ttttatccta
    46801 tcttgttagc cacctatggt tttgggatta gtttctatct gttgttttta ttggcgattt
    46861 caattttact aatgcttctt tatctaatga gtttgaatta caaagcatta gttcccgtta
    46921 ttaaggggag attacccctt aaacgcctga tgattttaac cctattgtgt cagttggttg
    46981 ctgtctttac agtaggatac gctgttaaga caggtttgac gtcttaccaa cgattgaaag
    47041 aacttgaaat ttcaaaacaa gcatggcagg atagagcaga ctattatcaa atttcttttg
    47101 gcttaggtga tagaggaaaa gatacagaaa atcagagcaa gtggtatgcc tttgccaagg
    47161 aagcaatcga agaagaacaa gctctttatg taaaggataa tctgctccat tttgccaatc
    47221 cacaaggaaa aaatgaacag ggagagacac tggataccta tagtccagat gctaatacgc
    47281 tctatgttag tcccagttat ttggacaagg aaaaggtcgt ggtagatgct gagaccaaac
    47341 agaagttagc ccatctccaa aaaggtgagt ttatcctctt gctcccagaa catttgcgct
    47401 ctcgagaagc agaacttaag aaagtttttg aagaaagatt gagttattat ggaaaatctg
    47461 gtgaggaggc aagtgctcct ttggattatg agatgaaagc gcacgttagt tatctttcaa
    47521 tgggagaaaa gcggtttgtt tataataacg gtgagaatcc cgtatccact cagtatttga
    47581 ttgatccgat tttagttgta ttcacgccga cttctacagg tgatagtttt atatccttat
    47641 ctagttggtc tatcaatgct ggaaaacaac tctttatcaa aggatatgag agtgggctag
    47701 aactcttgaa gaaagctgga atttatgagc aagtatccta tcttaaagaa ggaagaagtg
    47761 tttatctaac tcgttataat gaagttcaaa ctgaaacagc aactttaatc ttaggagcta
    47821 ttgtggggat agctagttcc ttgttactat tttattctgt caatcttcta tatttcgagc
    47881 aattccgccg agatattttg attaaacgaa tttcaggttt acgatttttt gaaacacatg
    47941 ctcagtatat ggttagtcaa tttgccagtt ttgtatttgg tgctagtctc tttattttaa
    48001 gcagtcgaga cttggtgatt ggcttgctca ctttattagt ctttctagct agtgcagttc
    48061 tgacgcttta ccgtcaagcg cagaaagaat ctcgtgtttc tatgacaatt atgaaaggaa
    48121 aataggatga ttgaactaaa gaatatatct aaaaaatttg gaagccgtca gctattttca
    48181 gatacaaatc ttcattttga aggtgggaaa atttatgcct taatcggtac aagtggctgt
    48241 ggtaagacaa cactcttgaa tatgattgga cgattagagc catatgacaa agggcaaatc
    48301 atctatgatg gcacttctct taaggacatc aagccttctg ttttctttag agattacttg
    48361 ggatacttat ttcaagattt tggcttaatt gaaagccaaa ccgtcaaaga gaatctcaat
    48421 ctgggtttag ttggtaaaaa gttgaaggaa aaagagaaaa tctctttgat gaaacaagct
    48481 ctaaaccgtg taaacctctc ttatttggat ttgaagcaac ctatatttga gttatcagga
    48541 ggagaagcac aacgtgttgc attagcgaag ataattttaa aggatccgcc tttgattctt
    48601 gcagatgaac caaccgcttc cttagacccc aaaaactctg aggaattact ttccatccta
    48661 gaatctttaa aaaatccgaa tcggaccatt attattgcga cccacaatcc tctgatttgg
    48721 gagcaagtgg atcaggtcat tcgagttacc gatttatcac atagataata tggtaagatt
    48781 cagttagaag aaagagtcac aaacacactt tgtggctttt ttatttccat aaaaatggta
    48841 aaatagtagg agtagaaatg gagttcgaga catgaaagta atagatcaat ttaaaaataa
    48901 gaaagttctt gttttaggtt tggccaagtc tggtgaatct gcagctcgtt tgttggataa
    48961 gctaggcgcc atagtgacag taaatgacgg gaaaccattc gaggacaatc cagctgccca
    49021 aagtttgctg gaagaaggga tcaaggtcat tacaggtggc catcctttgg aactcttgga
    49081 tgaagagttt gcccttatgg tgaaaaatcc aggtatcccc tacaacaatc ccatgattga
    49141 aaaggctttg gccaagggaa ttccagtctt gactgaggtg gaattggctt atttgatttc
    49201 agaagcaccg attattggta tcacaggatc gaacggtaag acaaccacaa cgactatgat
    49261 tggggaagtt ttgactgctg ctgggcaaca tggtctttta tcagggaata tcggctatcc
    49321 agctagtcaa gtggcccaaa ctgcgtcgga caaggacacg cttgttatgg aactttcttc
    49381 tttccaactc atgggtgttc aagaatttca tccagagatt gcggttatta ctaaccttat
    49441 gccaactcat atcgattatc atggattatt tgaggaatat gtagcagcca agtggaatat
    49501 ccagaacaag atgacagcag ctgatttcct tgtcttgaac tttaatcaag acttggcaaa
    49561 agacttgact tccaagacag aagccactgt tgtaccattt tcaacacttg aaaaggttga
    49621 tggagcttat ctggaagatg gtcaactcta cttccgtggt gaagtagtca tggcagcgaa
    49681 tgaaatcggt gttccaggta gccacaatgt ggaaaatgcc cttgcgacta ttgctgtagc
    49741 caagcttcgt ggtgtggaca atcaaaccat caaggaaact ctttcagcct tcggtggtgt
    49801 caaacaccgt ctccagtttg tggatgacat caagggtgtt aaattctata acgacagtaa
    49861 atcaactaat atcttggcta ctcaaaaagc cttgtcagga tttgacaaca gcaaggtcgt
    49921 cttgattgca ggtggtttgg accgtggcaa tgagtttgac gaattggtgc cagatattac
    49981 tggactcaag aagatggtca tcctgggtca atctgcagaa cgtgtcaaac gggcagcaga
    50041 caaggctggt gtcgcttatg tggaggcgac agatattgca gatgcgaccc gcaaggccta
    50101 tgagcttgcg actcaaggag atgtggttct tcttagtcct gccaatgcca gctgggatat
    50161 gtatgctaac tttgaagtac gtggcgacct ctttatcgac acagtagcgg agttaaaaga
    50221 ataaaatatg aaaaaaattg tctttacagg tggggggacg gttggacacg ttaccctcaa
    50281 tcttttgtta atgcccaagt tcatcgaaga tggttgggaa gtccactata tcggggacaa
    50341 gcgtggtatc gaacaccaag aaatccttaa gtcaggtttg gatgtcactt tccactccat
    50401 tgcgactggg aaattgcgtc gctatttctc ttggcaaaat atgctggacg tcttcaaagt
    50461 tggctgggga atcgtccaat cgctctttat catgttgcga cttcgtccac agaccctttt
    50521 ttcaaagggg ggctttgtct cagtaccgcc tgttatcgct gcgcgtgtgt caggagtgcc
    50581 tgtctttatt cacgaatctg acctgtctat gggcttggcc aataaaatcg cctataaatt
    50641 tgcgactaag atgtattcaa cctttgaaca agcttcgagt ttggctaagg ttgagcatgt
    50701 gggagcagtg accaaggttt cagatcaaaa aaatccagaa ccagatgaat tggtggatat
    50761 tcaaagccac tttaatcata aattgccgac tgtattgttt gttggcggtt ctgcaggtgc
    50821 tcgtgtcttt aaccaattgg tgacagacca taaaaaagaa ctaacagagc gctacaatat
    50881 tatcaatcta actggagatt ctagcctgaa tgagttgagc caaaatcttt ttcgtgttga
    50941 ctatgtgacc gatctctatc aacccttgat ggaattggct gatattgttg tgacacgtgg
    51001 tggtgccaat acgatttttg agctcttggc gatagcaaaa ttgcatgtca ttgtgccgct
    51061 tggtcgtgaa gctagtcgtg gtgaccagat tgaaaatgca gcttactttg ttaagaaagg
    51121 ctatgcagaa gaccttcaag aaagcgattt gaccttggat agtttggaag agaagctttc
    51181 tcacttacta agtcacaagg aagattacca agctaagatg aaagcttcta aggaattgaa
    51241 atctctagca gatttttatc aattgttgaa aaaagattta tcataaggaa agtaaatgtc
    51301 aaaagataag aaaaatgagg acaaagaaac cctcgaagaa ttgaaagagt tatcagaatg
    51361 gcagaaacga aaccaagaat atctaaaaaa gaaggctgaa gaagaggcgg ctctagctga
    51421 ggagaaggaa aaggaaagac aagctcgaat gggagaagaa tctgagaagt cagaggataa
    51481 acaggaccag gagagtgaaa cagaccagaa agattcagaa tcagctaagg aagagtctga
    51541 agaaaaagta gcatcctcag aggctgacaa agagaaagaa gagaaagaag aaccagagtc
    51601 taaagagaag gaggaacagg ataaaaagct tgctaaaaag gctacaaagg aaaaaccagc
    51661 caaagcaaag attcctggta tccatatctt gcgagccttc acgattttat ttccaagtct
    51721 gcttttattg attgtctctg cctacttgct cagtccttat gcgaccatga aagatattcg
    51781 tgttgaggga acggtgcaaa ctacagctga tgatattcga caggcttcag gcattcagga
    51841 ttcggattat acgattaacc ttctgctaga caaggcaaaa tatgaaaagc agattaagtc
    51901 taactattgg gttgaatcag ctcaacttgt ctatcaattt ccaactaagt tcactattaa
    51961 ggtcaaggaa tatgatattg tggcctacta tatttctggt gaaaatcatt atcctattct
    52021 ttccagtggt cagcttgaga ctagttctgt gagtctgaac agtttaccag aaacttattt
    52081 atcagttctc tttaatgata gtgaacaaat caaggttttt gtctcagaac ttgctcaaat
    52141 tagcccagaa ctcaaggcgg ctatccaaaa ggtggaatta gccccaagca aggtgacatc
    52201 cgatttaatt cgattgacca tgaatgattc ggacgaagtc ttggttcctc tatctgaaat
    52261 gagtaagaaa ctgccatatt acagtaagat taagccacaa ttgtcagaac cgagtgtgat
    52321 tgacatggaa gctggagtct acagctacac tgtagcggat aaattgatta tggaagcaga
    52381 agaaaaagct aaaaaagagg ccgaagaagc tgagaaaagg caggaagagg aacgtaaacg
    52441 tttagaagaa gaacagaaaa aacaagagga agagagcaat cgaaaccaaa cgacccagcg
    52501 ctcatcgcgt cgctaggttt taccttttct cctatagctc tttagttgcc atgtttttac
    52561 gtttaatatt tgacatctgt ttttctttat gttacatttg caatgtaatc gattacaaaa
    52621 aaatttttta tgaagaaggt aacacatatg tcagatgaag tattcttatt tgaagaaatt
    52681 gaagaaatcg tagcccctac agatggtgaa ttttgggggg ggagttttac ttggaactgg
    52741 ggtagttctc ttaattggag tagcctgttg ttaaaaagat agggagtgat aatcatgcaa
    52801 gataactttt tatttgagga aattgaagaa atttcagtac cagttagtga tttttcagct
    52861 ggacttgcaa caggtatcgg atttggttta gcaatccttg ctcttgctgg ttgttgaagt
    52921 ttgttcactt actaatatca agctttttca atttagacag tcatttgaat tttccgtatt
    52981 agtcttgcag caagagatta atagaattag tcattatttt attgattgcg gactgaggga
    53041 ctagagtatg ttttacttag cccctctttt atttattaaa ggttaggttt gttatgagaa
    53101 ttgttgataa gattaagata ttacctactc cttatgaggg acagtatcat ctatatatac
    53161 catccagtaa gaaacatgta ttagttggga aacaggaaaa aaatggttag agcaactaat
    53221 aggtcaagaa tttaccatat cggacttatt agtgttagta gggaagaaat attatttaag
    53281 attttatatt gttcttagta aaatgggact tatagattct atgaaatcac gaaaaaagat
    53341 aaatattttt aaaatatctt gggactttaa tataacatta tctgaaaaat taaactataa
    53401 aagatttaat aagaattttg aaaaaatcct atttggtatt ttcccattgg ctcttatttt
    53461 gcaatgtttt attatgtata tttatagggc ggatattttg actaatttcc aaaactttcc
    53521 aataacgcta aacattcttt tattttggtt gcttgttgtt attatatctg caacgataca
    53581 tgaatttagt catgcaataa ttgctaataa ttatcaaatt gagatcccaa attgtggaat
    53641 aatgctactt ttgtttaatt tggctttttt tgtagattta agtggggtgc aattcctaaa
    53701 aaataaaaaa caatttttga aaattatgtt agcaggaatt gcttcaaatt cgattttatc
    53761 acttacaggt ttacttgttt tattgttcac atcgtataaa ttgcttggac tcttattttt
    53821 tatcattaac ttaggtatga tttttattaa ttcaattcct ttttttcagt atgatagtgg
    53881 tattatttta agatacttga attctaacaa taataacttg aattttcaat atatagttca
    53941 acttttaata gcatttgtta ttatttattt ccctttgagt caactattac aatttttgac
    54001 acctaatatt attgttcgta gtataggagg ggtagttgtt tctatactgc tttctatatt
    54061 atatatgaga ggaaggacga aatatgttct acgtaaatag ttatgttttt gcttataaaa
    54121 aagaaggtat aatgtatttg cgtggtcgga gtatgcggga aatagctata gaacctcaaa
    54181 tttcgcaaga atttatcaac gatctattta atagttgtaa ggaactatta gagatagaag
    54241 aagtattagg tagtaaacta acatttgaac tattaaatga acaaatttta atttcggatg
    54301 agatagatat tgatagtaga tattctagaa ctaaaggtta ctattcgtta ttttataatg
    54361 aagagtataa taaaatacag aataaaacag tattagtatt aggagccgga gccttaggat
    54421 gttatatatc tctaagtcta agtatgtatg gagtgaggaa acttattgtc gctgattacg
    54481 atataataga accatcaaat ttaaataggc aaattcttta tacagagtcg gatgttggta
    54541 aggagaagat taatgttctt tctcaaaaaa tacacaagta taattcagat gttcaggtag
    54601 tacctatttc tattaaagtt tcttcagtag aagaattaga aaacattgtt gcggaatatg
    54661 ggagtataga ttttatcgtt aaagcaattg atacgcccat tgatattata aaaattgtca
    54721 atcaatttgc tgtatcgcat aagatatcct acatatcagg agggtttaat ggatgctatc
    54781 ttattattga taatatatat atccctacca tcggttcttg ctttgcttgt cggaatataa
    54841 acaaagatat aaataagtac actttatctg ataagacaaa gtggccgact acaccagaga
    54901 tgcctgctat tttgggaggg ataatgacta atttaataat taaaatattt ctgggatgtt
    54961 ataatgaaat cctaatagat aacgcttacg tttataatat gagaaatcat gctctaagtc
    55021 aagaaaaata tgttctggaa aacggagaat gtccaatttg taaaaaaaat aataaagtga
    55081 aagataacaa tattagagcg aaaacattta ttcgttcagt ttgtttttgc ttattatcag
    55141 gaggagtagc ttttttatct gctattgggc agttcactgt tataga
//
LOCUS       DAVKEV010000004        55004 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVKEV010000004 DAVKEV010000000
VERSION     DAVKEV010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55004
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.004"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..626
                     /locus_tag="VWZ68_000246"
     CDS             <1..626
                     /locus_tag="VWZ68_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371341.1"
                     /translation="FKFANVIIFVVRSLIKLDQMGLELTNGGIIEVFIPNHLRKLKNF
                     IEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDWNYSDLVMKFTSNFYADIKDLFMEN
                     SDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLNFFYKQLGITLYARNSFGFRNLTVE
                     YFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSFSNEYLKTTDEVNR"
     gene            623..1801
                     /locus_tag="VWZ68_000247"
     CDS             623..1801
                     /locus_tag="VWZ68_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9371342.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            2226..2459
                     /locus_tag="VWZ68_000248"
     CDS             2226..2459
                     /locus_tag="VWZ68_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9371343.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            2742..4691
                     /gene="mutL"
                     /locus_tag="VWZ68_000249"
     CDS             2742..4691
                     /gene="mutL"
                     /locus_tag="VWZ68_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEU9371344.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(5016..5483)
                     /locus_tag="VWZ68_000250"
     CDS             complement(5016..5483)
                     /locus_tag="VWZ68_000250"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEU9371345.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIAVAWIPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(5484..6689)
                     /locus_tag="VWZ68_000251"
     CDS             complement(5484..6689)
                     /locus_tag="VWZ68_000251"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEU9371346.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(6709..7344)
                     /gene="ribE"
                     /locus_tag="VWZ68_000252"
     CDS             complement(6709..7344)
                     /gene="ribE"
                     /locus_tag="VWZ68_000252"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEU9371347.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(7329..8429)
                     /gene="ribD"
                     /locus_tag="VWZ68_000253"
     CDS             complement(7329..8429)
                     /gene="ribD"
                     /locus_tag="VWZ68_000253"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEU9371348.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(8564..8678)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            8835..9428
                     /gene="ruvA"
                     /locus_tag="VWZ68_000254"
     CDS             8835..9428
                     /gene="ruvA"
                     /locus_tag="VWZ68_000254"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEU9371349.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            9438..10001
                     /locus_tag="VWZ68_000255"
     CDS             9438..10001
                     /locus_tag="VWZ68_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEU9371350.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            9998..10675
                     /locus_tag="VWZ68_000256"
     CDS             9998..10675
                     /locus_tag="VWZ68_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9371351.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIATYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVDYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(10830..11861)
                     /locus_tag="VWZ68_000257"
     CDS             complement(10830..11861)
                     /locus_tag="VWZ68_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEU9371352.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKVLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEEPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDNNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(12116..12799)
                     /locus_tag="VWZ68_000258"
     CDS             complement(12116..12799)
                     /locus_tag="VWZ68_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEU9371353.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(12811..13755)
                     /locus_tag="VWZ68_000259"
     CDS             complement(12811..13755)
                     /locus_tag="VWZ68_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU9371354.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            13887..16718
                     /gene="uvrA"
                     /locus_tag="VWZ68_000260"
     CDS             13887..16718
                     /gene="uvrA"
                     /locus_tag="VWZ68_000260"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEU9371355.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            16711..17772
                     /locus_tag="VWZ68_000261"
     CDS             16711..17772
                     /locus_tag="VWZ68_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU9371356.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLFPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            17904..18302
                     /gene="spx"
                     /locus_tag="VWZ68_000262"
     CDS             17904..18302
                     /gene="spx"
                     /locus_tag="VWZ68_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEU9371357.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            18368..18937
                     /locus_tag="VWZ68_000263"
     CDS             18368..18937
                     /locus_tag="VWZ68_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU9371358.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLVGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            19024..19290
                     /locus_tag="VWZ68_000264"
     CDS             19024..19290
                     /locus_tag="VWZ68_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEU9371359.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            19294..19713
                     /gene="ruvX"
                     /locus_tag="VWZ68_000265"
     CDS             19294..19713
                     /gene="ruvX"
                     /locus_tag="VWZ68_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEU9371360.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            19729..20034
                     /locus_tag="VWZ68_000266"
     CDS             19729..20034
                     /locus_tag="VWZ68_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEU9371361.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            20447..21697
                     /locus_tag="VWZ68_000267"
     CDS             20447..21697
                     /locus_tag="VWZ68_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU9371362.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSCREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            21694..22251
                     /locus_tag="VWZ68_000268"
     CDS             21694..22251
                     /locus_tag="VWZ68_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEU9371363.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQP
                     TDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKI
                     YTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            22397..23929
                     /gene="cls"
                     /locus_tag="VWZ68_000269"
     CDS             22397..23929
                     /gene="cls"
                     /locus_tag="VWZ68_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEU9371364.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGINLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            24007..24150
                     /locus_tag="VWZ68_000270"
     CDS             24007..24150
                     /locus_tag="VWZ68_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371365.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            24187..25725
                     /locus_tag="VWZ68_000271"
     CDS             24187..25725
                     /locus_tag="VWZ68_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU9371366.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFEFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            25845..28052
                     /gene="nrdD"
                     /locus_tag="VWZ68_000272"
     CDS             25845..28052
                     /gene="nrdD"
                     /locus_tag="VWZ68_000272"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEU9371367.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            28064..28204
                     /locus_tag="VWZ68_000273"
     CDS             28064..28204
                     /locus_tag="VWZ68_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371368.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            28248..28754
                     /locus_tag="VWZ68_000274"
     CDS             28248..28754
                     /locus_tag="VWZ68_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9371369.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNLASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            28747..29337
                     /gene="nrdG"
                     /locus_tag="VWZ68_000275"
     CDS             28747..29337
                     /gene="nrdG"
                     /locus_tag="VWZ68_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEU9371370.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            29334..29951
                     /locus_tag="VWZ68_000276"
     CDS             29334..29951
                     /locus_tag="VWZ68_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEU9371371.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQASMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            30217..30525
                     /gene="rpsJ"
                     /locus_tag="VWZ68_000277"
     CDS             30217..30525
                     /gene="rpsJ"
                     /locus_tag="VWZ68_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEU9371372.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            30742..31368
                     /gene="rplC"
                     /locus_tag="VWZ68_000278"
     CDS             30742..31368
                     /gene="rplC"
                     /locus_tag="VWZ68_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEU9371373.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            31393..32016
                     /gene="rplD"
                     /locus_tag="VWZ68_000279"
     CDS             31393..32016
                     /gene="rplD"
                     /locus_tag="VWZ68_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEU9371374.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            32016..32312
                     /locus_tag="VWZ68_000280"
     CDS             32016..32312
                     /locus_tag="VWZ68_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEU9371375.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            32330..33163
                     /gene="rplB"
                     /locus_tag="VWZ68_000281"
     CDS             32330..33163
                     /gene="rplB"
                     /locus_tag="VWZ68_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEU9371376.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            33267..33548
                     /gene="rpsS"
                     /locus_tag="VWZ68_000282"
     CDS             33267..33548
                     /gene="rpsS"
                     /locus_tag="VWZ68_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEU9371377.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            33560..33904
                     /gene="rplV"
                     /locus_tag="VWZ68_000283"
     CDS             33560..33904
                     /gene="rplV"
                     /locus_tag="VWZ68_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEU9371378.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            33917..34570
                     /gene="rpsC"
                     /locus_tag="VWZ68_000284"
     CDS             33917..34570
                     /gene="rpsC"
                     /locus_tag="VWZ68_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEU9371379.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            34574..34987
                     /gene="rplP"
                     /locus_tag="VWZ68_000285"
     CDS             34574..34987
                     /gene="rplP"
                     /locus_tag="VWZ68_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEU9371380.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            34997..35203
                     /locus_tag="VWZ68_000286"
     CDS             34997..35203
                     /locus_tag="VWZ68_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEU9371381.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            35228..35488
                     /gene="rpsQ"
                     /locus_tag="VWZ68_000287"
     CDS             35228..35488
                     /gene="rpsQ"
                     /locus_tag="VWZ68_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEU9371382.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            35514..35882
                     /gene="rplN"
                     /locus_tag="VWZ68_000288"
     CDS             35514..35882
                     /gene="rplN"
                     /locus_tag="VWZ68_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEU9371383.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            35960..36265
                     /gene="rplX"
                     /locus_tag="VWZ68_000289"
     CDS             35960..36265
                     /gene="rplX"
                     /locus_tag="VWZ68_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEU9371384.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            36289..36831
                     /gene="rplE"
                     /locus_tag="VWZ68_000290"
     CDS             36289..36831
                     /gene="rplE"
                     /locus_tag="VWZ68_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEU9371385.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            36849..37118
                     /gene="rpsN"
                     /locus_tag="VWZ68_000291"
     CDS             36849..37118
                     /gene="rpsN"
                     /locus_tag="VWZ68_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEU9371386.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            37403..37801
                     /gene="rpsH"
                     /locus_tag="VWZ68_000292"
     CDS             37403..37801
                     /gene="rpsH"
                     /locus_tag="VWZ68_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEU9371387.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            37993..38529
                     /gene="rplF"
                     /locus_tag="VWZ68_000293"
     CDS             37993..38529
                     /gene="rplF"
                     /locus_tag="VWZ68_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEU9371388.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            38613..38969
                     /gene="rplR"
                     /locus_tag="VWZ68_000294"
     CDS             38613..38969
                     /gene="rplR"
                     /locus_tag="VWZ68_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEU9371389.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            38987..39481
                     /gene="rpsE"
                     /locus_tag="VWZ68_000295"
     CDS             38987..39481
                     /gene="rpsE"
                     /locus_tag="VWZ68_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEU9371390.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            39453..39677
                     /gene="rpmD"
                     /locus_tag="VWZ68_000296"
     CDS             39453..39677
                     /gene="rpmD"
                     /locus_tag="VWZ68_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEU9371391.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            39822..40262
                     /gene="rplO"
                     /locus_tag="VWZ68_000297"
     CDS             39822..40262
                     /gene="rplO"
                     /locus_tag="VWZ68_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEU9371392.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            40275..41585
                     /gene="secY"
                     /locus_tag="VWZ68_000298"
     CDS             40275..41585
                     /gene="secY"
                     /locus_tag="VWZ68_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEU9371393.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            41736..42374
                     /locus_tag="VWZ68_000299"
     CDS             41736..42374
                     /locus_tag="VWZ68_000299"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEU9371394.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            42491..42709
                     /gene="infA"
                     /locus_tag="VWZ68_000300"
     CDS             42491..42709
                     /gene="infA"
                     /locus_tag="VWZ68_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEU9371395.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            42734..42850
                     /gene="rpmJ"
                     /locus_tag="VWZ68_000301"
     CDS             42734..42850
                     /gene="rpmJ"
                     /locus_tag="VWZ68_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEU9371396.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            42868..43233
                     /gene="rpsM"
                     /locus_tag="VWZ68_000302"
     CDS             42868..43233
                     /gene="rpsM"
                     /locus_tag="VWZ68_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEU9371397.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            43251..43634
                     /gene="rpsK"
                     /locus_tag="VWZ68_000303"
     CDS             43251..43634
                     /gene="rpsK"
                     /locus_tag="VWZ68_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEU9371398.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            43677..44612
                     /locus_tag="VWZ68_000304"
     CDS             43677..44612
                     /locus_tag="VWZ68_000304"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEU9371399.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            44624..45010
                     /gene="rplQ"
                     /locus_tag="VWZ68_000305"
     CDS             44624..45010
                     /gene="rplQ"
                     /locus_tag="VWZ68_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEU9371400.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            45275..45541
                     /locus_tag="VWZ68_000306"
     CDS             45275..45541
                     /locus_tag="VWZ68_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEU9371401.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            45551..46888
                     /locus_tag="VWZ68_000307"
     CDS             45551..46888
                     /locus_tag="VWZ68_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEU9371402.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            47132..47824
                     /locus_tag="VWZ68_000308"
     CDS             47132..47824
                     /locus_tag="VWZ68_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU9371403.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(47927..49572)
                     /locus_tag="VWZ68_000309"
                     /pseudo
     CDS             complement(47927..49572)
                     /locus_tag="VWZ68_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(49562..50653)
                     /locus_tag="VWZ68_000310"
                     /pseudo
     CDS             complement(49562..50653)
                     /locus_tag="VWZ68_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(50666..51787)
                     /locus_tag="VWZ68_000311"
                     /pseudo
     CDS             complement(50666..51787)
                     /locus_tag="VWZ68_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(52004..52201)
                     /locus_tag="VWZ68_000312"
     CDS             complement(52004..52201)
                     /locus_tag="VWZ68_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU9371404.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(52276..53052)
                     /locus_tag="VWZ68_000313"
     CDS             complement(52276..53052)
                     /locus_tag="VWZ68_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEU9371405.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            53174..53920
                     /locus_tag="VWZ68_000314"
     CDS             53174..53920
                     /locus_tag="VWZ68_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9371406.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            53933..54913
                     /locus_tag="VWZ68_000315"
     CDS             53933..54913
                     /locus_tag="VWZ68_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEU9371407.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
BASE COUNT        16794 a         9989 c        11848 g        16373 t
ORIGIN      
        1 aatttaaatt tgcgaatgta attatttttg tggtacgatc tttgataaaa ttagatcaaa
       61 tgggattaga attgacaaat gggggaataa tagaagtgtt tattcctaat catttgagaa
      121 agttgaaaaa ttttattgaa gaggaattca ataaatttag aaattctcac ggagctaatc
      181 taagcctcta tgaatactgt ttgcttgata attctttaac tttaaaaaat gattggaact
      241 attctgattt agttatgaaa tttacgagta atttttatgc tgatataaaa gacttgttca
      301 tggaaaattc tgatattgaa atcatccatg aagagggagt accttttgta tttttagatt
      361 taataggtga aggtaaaaaa gaatatgaaa tgttttttca atggttaaac ttcttttaca
      421 aacagcttgg aatcacattg tatgctagaa atagttttgg gtttcggaat ctaacagtag
      481 agtattttgg aattattggg acagaaagat atatatttaa gatttgtcca ggtgtttata
      541 aagggttaag ttattatttg atgaaatttt tattaaaatc tttttcaaat gaatatttaa
      601 aaactactga tgaggttaat agatgaaaaa tttgataaag ttgctaataa ttagattgat
      661 tgttaactta gcagacagtg tattttatat agtagcattg tggcacgtta gcaataatta
      721 ttcttcgagc atgttcttag gaatatttat tgcagtaaat tatctaccgg atttgttact
      781 aatctttttt ggaccagtta ttgacagagt aaatccgcaa aaaattctta taatatcaat
      841 tttggttcaa ttagcagtgg ctgtaatatt tttattatta ttaaaccaaa tatcattttg
      901 ggtgataatg agtctagtgt ttatttcagt aatggctagc tccataagtt acgtgataga
      961 agatgtgttg attcctcaag tggtagaata tgataagatt gtatttgcaa attctctttt
     1021 tagtatttcg tataaagtat tagattctat ttttaattca ttcgcatcat ttttacaggt
     1081 ggcagtagga tttattttat tggttaagat agatataggc atatttttac ttgctctatt
     1141 tatattgttg ttgttaaaat ttagaactag caatgcgaat atagaaaact tctctttcaa
     1201 atattacaag agagaagtgt tgcaaggtac aaagtttatt ttaaataata aattattatt
     1261 taaaaccagt atttctttaa cgcttataaa ctttttttat tcatttcaga cagtagttgt
     1321 accgattttt tctattcgat attttgatgg tccgattttt tatggtattt ttttaactat
     1381 tgctggtttg ggtggtatat tgggaaatat gctagcgcca atcgtaataa aatatttaaa
     1441 atcgaatcaa attgttggtg tatttctttt tttgaacggc tcaagttggt tagtagcaat
     1501 tgttataaaa gactatactt tatcacttat tttatttttc gtttgtttta tgtctaaagg
     1561 agtcttcaat attattttta attcgttgta ccaacaaata cctccacatc aacttcttgg
     1621 tagggtaaat actaccattg attctattat ttcttttgga atgccaattg gtagtttagt
     1681 tgcaggaacg cttattgatt tgaatattga attagtgtta attgctatta gcatacctta
     1741 ttttttgttt tcttatattt tttatacgga taatggattg aaagaattta gtatatatta
     1801 gaaatgttta tgttcattca aaagcataat gactataact gaaaaagaaa agtgatatct
     1861 ttaaggttgt tcttcttggt ggtgagattc gtgagacaac ccaagctttt gtcggaaaga
     1921 ttaccaatgc tttgatggat aggatgtact ttagcaagat gtttttagtg gtaacggtat
     1981 cgtggatgga cgtgtaataa cctcttcttt cgaggagtat tttactaaaa aactagcctt
     2041 ggagcgttcc ccagaaacgg acttactcat tgactcttca aagatttggg gagaagattt
     2101 tgcttcatct gttccttgaa aaaagtcaca gcagtcatca cagacgatag tactgaacaa
     2161 aactatgaag agttagaaat ttatacgcag gtgattgtat aaaggatctg gaaatagata
     2221 agaagttgat tagtattgac ctaggtggta caaatattaa gattactgtt ctttcaaatg
     2281 acggtgagat tgaaactttg tggagtatta caacagatac aagtgagaaa ggttctcaaa
     2341 ttatatcgga catcatcagt tctattaaaa ataaattgac cgaacggaat attcctgata
     2401 gcgaccttct tggaatcggt atgggaagtt gctcatcata ctttccttgt aaatcatagg
     2461 ggctataaac tctccgtcta cttgtcctgc aacaattgaa gtctgctcaa aacgccgtcc
     2521 gctaatcttt tcatagactt tctccctttt aggagcctag ctttctagtt tgttctttga
     2581 tttttattga gtataccact attttactcc ctctggcaag ggactttgtc tatgtggagg
     2641 gattgggctc ctatgtggtg gagcttttct gttctttctg aaatatggta taatagcact
     2701 aatcaatttc taggaaaata gatacagaaa ggggctgaaa gatgtctcat attattgaat
     2761 tgccagagat gctggcaaac caaatcgcgg ctggagaggt cattgaacgt cctgccagtg
     2821 tggtcaaaga gttggtagaa aatgccattg acgcgggctc tagtcagatt atcattgaga
     2881 ttgaggaagc tggtctcaag aaggttcaaa tcacggataa cggtcatgga attgcccacg
     2941 atgaggtgga gttggccctg cgtcgccatg cgaccagtaa gataaaaaat caagcagatc
     3001 tctttcggat tcggacgctt ggttttcgtg gtgaagcctt gccttctatt gcgtctgtta
     3061 gtgtcttgac tctgttaacg gcggtggatg gtgctagtca tggaaccaag ttagtcgcgc
     3121 gtgggggtga agttgaggaa gtcatcccag cgactagtcc tgtgggaacc aaggtttgtg
     3181 tggaggatct ctttttcaac acgcctgccc gtctcaagta tatgaagagc cagcaagcgg
     3241 agttgtctca tatcattgat attgtcaacc gtctgggctt ggcccatcct gagatttctt
     3301 ttagcttgat tagtgatggc aaggaaatga cgcggacagc agggactggt caactgcgcc
     3361 aagcaatcgc aggaatttac ggtttggtca gtgccaagaa gatgattgaa attgagaact
     3421 ctgacctaga tttcgaaatt tcaggttttg tgtccttgcc tgagttgact cgggctaacc
     3481 gcaattatat cagcctcttc atcaatggcc gttatattaa gaacttcctg ctcaatcgtg
     3541 ctattttgga tggttttgga agcaagctta tggttggacg ttttccactg gctgtcattc
     3601 acatccatat cgacccttat ctagcggatg tcaatgtgca tccaactaag caagaggtgc
     3661 ggatttccaa ggaaaaagaa ctgatgactc tggtttcaga agctattgca aatagtctca
     3721 aggaacaaac cttgattcca gatgccttgg aaaatcttgc caaatcgacc gtgcgcaatc
     3781 gtgagaaggt ggagcaaact attctcccac tcaaagaaaa tacgctctac tatgagaaaa
     3841 ctgagccgtc aagacctagt caaactgaag tagctgatta tcaggtagaa ttgactgatg
     3901 aagggcagga tttgaccctg tttgccaagg aaaccttgga ccgattgacc aagccagcaa
     3961 aactgcattt tgcagagaga aagcctgcta actacgacca gctagaccat ccagagttag
     4021 atcttgctag catcgataag gcttatgaca aactggagcg agaagaagca tccagcttcc
     4081 cagagttgga gtttttcgga caaatgcacg ggacttatct ctttgcccaa gggcgagatg
     4141 gactttacat catagatcag cacgctgctc aggaacgggt caagtacgag gagtaccgtg
     4201 aaagcattgg caatgttgac cagagccagc agcaactcct agtgccctat atctttgaat
     4261 ttcctgcgga tgatgccctg cgtctcaagg aaagaatgcc tctcttagag gaagtgggcg
     4321 tctttctagc agagtacgga gaaaatcaat ttattctacg tgaacatcct atttggatgg
     4381 cagaagaaga gattgaatca ggcatctatg agatgtgcga catgctcctt ttgaccaagg
     4441 aagtttctat caagaaatac cgagcagagc tggctatcat gatgtcttgc aagcgatcta
     4501 tcaaggccaa tcatcgtatt gatgatcatt cagctagaca actcctctat cagctttctc
     4561 aatgtgacaa tccctataac tgtcctcacg gacgtcctgt tttggtgcat tttaccaagt
     4621 cggatatgga aaagatgttc cgacgtattc aggaaaatca caccagtctc cgtgagttgg
     4681 ggaaatatta aaagtataaa aaagtctggg aaaaattttc aaaatcagaa aaacgcataa
     4741 aatcaggtgt tcaaaaacct tgattttatg cgttttatca tagaaatatt tacttcattt
     4801 tttcctaatt cttttcgaaa ctctttttaa acgacgtcag ttttatcagt aatctcaaaa
     4861 cagtgttttg agctaatttt gccagttttg tctgtaacat cgaagttgtg ttttaccact
     4921 ctgcgactgg tttcctagtt tgctctatga ttttcacaga gtattaaatt gcgattttgc
     4981 caagtttctt tattcgtcta aaagtagagt ctgttctatg cgtctaatgt acgaattagg
     5041 ttgaccattt caatagctcc ttgtgcacac tcagaaccct tatttcctgc tttagtgcca
     5101 gctcgttcta tggcttgttc aattgtatct gtcgttagca caccaaacat aacaggaatt
     5161 tcgctattta aactgatttg ggcgattccc ttagatacct cgctacatac ataatcataa
     5221 tgacttgtat tccctctaat gacagctccc aagcagataa ttgcatcata ttttttactt
     5281 tttgccattt ttgatgcaat cagtggtatt tcaaaagctc ctggaatcca ggctaccgct
     5341 atatctttct cgtttacatt ctctcttttg agattatcta gtgctccaga taataatttt
     5401 gaagttataa attcattaaa tctcgctaca acaataccta ttttaatatt gtttgctact
     5461 aaattacctt cataagtgtt catttatttt tcctccatat ttaaaatgtg acccattcga
     5521 tttttctttg tttctaaata aaaactatcg taaggattgg cttctatttc gattgatatt
     5581 ctactggaaa tggtaattcc atatttttct aactgttcaa ccttgtcagg attatttgtc
     5641 agtaaatgaa gtgactgaag tcccagatct ttaagcattt gtgctccaat atgatattct
     5701 cttaaatcac cttcaaagcc taatgcaaga ttggcatcaa gcgtatccat gccttgatct
     5761 tgtaaatgat aggcttttaa tttattgata agtccaattc ctcgtccctc ctgtcgcaag
     5821 taaagtaaga cacccgaacc attctcaaca atcattttca tagctttatc gaattgctgt
     5881 ccacaatcgc aacgtaaaga gcctaaaaca tcccctgtta aacattcgga gtggacccga
     5941 cataatacat tggcttcatc ctctatgttt cccataataa gagcaagatg atgttcccca
     6001 tttagtttat ctatatagct aattgctttg aaattaccgt atctagtagg catattgaca
     6061 gttgaaactc gttctaccag ctgatcatat acttttctat attcttgtaa ttctttgatg
     6121 gtaattagtg gaatgttgtg tttcttcgag aactgaatta aatcatctgt tctcatcatt
     6181 ttgccatcat gattcattat ttcacaacat aggccacact cttttagtcc agctaatttt
     6241 aataaatcaa cagttgcttc tgtgtgtcca tttctttcta gaacaccacc tttttttgca
     6301 attaaaggaa acatgtgtcc tggcctgcga aaatcagagg gtgttatatc ttcagctaca
     6361 cacatacgtg cggtcagtcc tctttcctcg gcagaaatac ctgtggtcgt ttctttataa
     6421 tcaattgaaa ctgtaaaagc agtcttatga ttatctgtat tgttttcaac cataggtgaa
     6481 agcattaatt gattagctaa actttcgctc ataggcatac aaattaatcc tttggcataa
     6541 gtagccataa aattaacatt ttctgttgta gctgcttgtg cagaacaaat taagtctcct
     6601 tcattttctc tatccttgtc gtctataaca agaacaagtc gtcccttctg caatgcttct
     6661 aatgcttctt gtatttttcg atattccatt gactgattat cctttctgct aaaatccatt
     6721 ttgatataat agttccttag atatttctga ttttggagag ttatccatca gtttttgcac
     6781 atatttacct aagatatcat tttcaagatt tactgtactc ccgacttgtt tactcttaag
     6841 aatggtttgt tccaaggtat gagggataac agatactgaa aagtttactt tggagacttt
     6901 agcgacagtc agactaatgc cgtcaattgt aatagatcct ttttcaacta ttaaatctaa
     6961 aatttctttt tgtgtgttga tttgatacca tacagcatta tcatcttttt ttattgacga
     7021 gatttttcct gtaccatcaa tgtgtcctgt aacgacgtga cccccaagtc gaccgttgac
     7081 agataaggct ctttctagat tcacctcact tccatgtttt aatagagtaa gagctgttcg
     7141 actccatgtt tcattcatta catcaactgt aaaggattga tggttgaaat gagtaactgt
     7201 aagacagata ccatttactg ctatactatc gcctaaatgg atatccgtta atatttttga
     7261 ggctttaatt gatagtttac aattacgaga gtctttctgt attctttcaa cttttccgat
     7321 ttcttcaatt attcctgtga acatggataa atcacttcac tttctatgag atagtcattt
     7381 cctatttgag aaaaagcata aggtttcaat ctaatagcgt catttggcaa agaaatgcct
     7441 tcacctccga caggaaactt ggcactgcct ccaaaaattt ttggtgcaat atatattttc
     7501 agctcatcaa caatttgttg ttccaaagca ctccaattca ttagactgcc cccttctaga
     7561 actaggctat caatctgcat gtttcctaga tgttgcatta aactcgataa gtctatatga
     7621 ttgccttttt tctttatgga aagtatttca cagccatgat tttgatatag cttcatttta
     7681 tttttgtctt cagaggaagt ggcaatgtaa gttttaatat catttgctgt ttttacgatt
     7741 ttagaggtaa gaggagttcg taaatgtgta tcgcatatga tacggatagg atttttccct
     7801 tcctccaatc tacatgtcag caaaggatcg tcttgaataa cagtattgac tcccaccata
     7861 attgcactaa catagtgtcg taactgatgc acatgctttc ttgcttcttc ttcagtaatc
     7921 catttggatt gatttgtttt agtggctatt tttccatcca ttgacattgc atatttcata
     7981 aaaacatagg gtacatgctg ggtaatatac tttctaaaac tttttattaa gttaagacac
     8041 tcattttcta aaattccaac agtaacttga agattatttt cctcaagtat ctttactcct
     8101 tttccagata caataggatt acagtctagg cttccaatga ctactcttgt aataccacta
     8161 tcgattatag catctataca gggaggtgtt ttcccgaagt gacaacaggg ttcaagtgtt
     8221 acataaagcg tcgctccgac aggggattct ctacagtttt taagagcatt tctctcagca
     8281 tgtgggccac caaaaaactc atgataacct tgtccgatga tgtgattatc ttttacaata
     8341 actgcgccga ccataggatt gggattgacg taaccagccc ctttttgtgc cagttttatt
     8401 gctaatttca tatattttga atcgctcatc tcactacctc caaaaaaaat ataccttgaa
     8461 taggggacta ctcaaggcat acaaaagaaa acttatgcga ttaacaaaaa tactctgaaa
     8521 tgacaagtaa tcatttcaga gcacgcaaaa agcacaaata tacttttatc ttctttcatc
     8581 cagactatac tgtcggcttt ggaatttcac caaatcatgc ctttcggctc gtgggctata
     8641 ccaccggtag ggaattacac cctgccctga agatagttat tcaattacag atgattatag
     8701 tacttaattt tgaatatgtc aacagataaa taccgattgt ttttgatata ctgtatttgt
     8761 gataatcgat tctcgctcct cggataaaga aaatatgata tactagataa acgaaataag
     8821 agagaaggaa tactatgtac gcatatttaa aaggaatcat taccaaaatt actgccaaat
     8881 acattgttct tgaaaccaat ggtattggtt atatcctgca tgtggccaat ccttatgcct
     8941 attcaggtca ggttaatcag gaggctcaga tttatgtgca tcaggttgtg cgtgaggacg
     9001 cccatttgct ttatggattt cgctcagagg atgagaaaaa gctctttctt agtctgattt
     9061 cggtctctgg gattggtcct gtatcagctc ttgctattat cgctgctgat gacaatgctg
     9121 gcttggttca agccattgaa accaagaaca tcacctactt gaccaagttc cctaaaattg
     9181 gcaagaaaac agcccagcag atggtgctgg acttggaagg caaggtagta gttgcaggag
     9241 atggccttcc tgccaaggtc gcagtgcaag caagtgctga aaaccaagaa ttggaagaag
     9301 ctatggaagc catgttggct ctgggctaca aggcaacaga gctcaagaaa atcaagaaat
     9361 tctttgaagg aacgacagat acagctgaga actatatcaa gtcggccctt aaaatgttgg
     9421 tcaaatagga gcagagaatg acaaaacgtt gttcgtgggt caagatgacc aacccgctct
     9481 acatcgccta tcatgatgag gagtggggtc agcccctcca tgatgaccaa gcattgtttg
     9541 agttgttgtg tatggaaacc tatcaggcag gcctgtcttg ggaaacggta ctcaacaaac
     9601 gccaagcttt ccgagaagcc tttcatagct atcaaattca ctcagtcgca gagatgactg
     9661 acactgaatt ggaagccatg ctggagaatc cagctatcat tcgaaataga gccaagattt
     9721 ttgctacacg cgctaacgcc caagcctttc tacagttaca ggcagagtac ggctcttttg
     9781 atgcctatct ttggtctttt gttgagggga aaactgtcgt taacgatgtt cctgattatc
     9841 gccaagcccc agctaaaaca cccttatctg agaaattagc caaagatctc aaaaaacgag
     9901 gcttcaagtt cacaggccca gtcgccgtat tgtcttttct acaggctgca gggctagttg
     9961 atgaccacga gaatgattgt gagtggaaag gtcttaaatg atgtctaaca aaaataaggg
    10021 aattctgatt tttgcgattc tctatacagt cctctttgtg tttgatggcg ttaaattgct
    10081 ggcttcttta atgccatctg ccattgcaac ttatcttgtt tatgtagttt tagctttata
    10141 tggctccttc ttgttcaagg atagattgat ccaacaatgg aaggagatta gaaagactaa
    10201 aagaaaattc ttctttggag tcttaacagg atggctcttt ctcattctga tgactgttgt
    10261 ctttgaattt gtatcagaga tgttgaagca gtttgtggga ctagatggac aaggtctaaa
    10321 tcagtctaat attcaaagta cctttcaaga acaaccacta ctgatagctg tttttgcttg
    10381 tgtcattgga cctctggtag aagaattatt tttccgtcag gtcttattgc attacttgca
    10441 ggaacggttg ccaggtttac taagcattat tctggtagga cttgtttttg ctctgactca
    10501 tatgcacagt ttggctctat cagagtggat tggtgcagtt gattacttag gtggaggcct
    10561 tgccttttct attatttatg tgaaagaaaa agagaatatc tactatcccc tacttgttca
    10621 catgttaagc aacagcctct ccttaatcat tttagctatc agtatagtaa aatgaaataa
    10681 gaacaggaca aatcaatcag gacagtcaaa tcgatttcta acaatgtttt agaagtagag
    10741 gtgtactatt ctagtttcaa tacactgtaa catgtgatga aaatgccagt aatgataccg
    10801 agaaaaaagc tgagaaactt ttcccagctt tatttgttat agtcaaagcg aatgacttgt
    10861 tcctgtgcat ctacatgagc atggacccca aagggtacaa ttgctcttgg agttgcgtgg
    10921 ccgacattca gattatagac aatcgggata ttgttgtcaa tgatatccaa tagtgcctct
    10981 ttatagtcgt catggaaagt ttcatccata ggttttccga ccaagagtcc attgatgacc
    11041 gcgaatatgc cagtgtcctt taaagttagc aacatctttt tgaagtcttc tggcttaggc
    11101 tcttcttcgc ttgtttcgag caagaggatt ttcccttccc agtctgacaa gtcagggaaa
    11161 agtttgtatt tttggcagag ttccgtgcta tctgcgtatc gagagttgtc aaagatatcg
    11221 tagagggatt cgaggcaacc accgaggatt ttcccctcga actgagcact tccttgcaac
    11281 aagtcaaaac ctgtatttgt atgactgaca cgaggtgttc ccagggccgt gggactaaaa
    11341 tcagttcgtt cctcatacca aacgtcacta gggcggattt ctgaaattct tcccgtctca
    11401 atcaattctt taaagtagtg aaggctatag gctagcattt ctttgtctaa ttcacaaatg
    11461 tctgctaaaa aggattgacc ataaaaagtc ttgattccta atttatgcaa catgaggtgg
    11521 ttcatggttg tatccgagaa gccaagaaaa attttttgtt tgataacctt ttggagttgg
    11581 tcattttcaa aaagataagg tagcaagcga taggtatcgt ctccacctat ggcacatagg
    11641 atcatgtcga tgctatcatc agaaaaggca tgaatcaaat cctctgcacg agcttcagga
    11701 tggtccttga taaagtctaa tccttttaac gaatggggca aaaagatggg attgagtccc
    11761 agaaccttga gacgttggat acccaagtcc acttcgtgtt tgacaaaatc ctctccgata
    11821 atgccactag ataaactaac aataccaata gtagaaacca tatctcatcc tcctagaaat
    11881 agattgagcc tattttatca caaaatataa gagaaagcta tgtgggattt cagaagaata
    11941 cttttaatac tcttcgaaaa tctcttcaaa ccacgtcagt tttatctgca acctcaaagc
    12001 tgtgctttga gcaacctgca gctagcttcc tagtttgctc tttgattttc attgagtata
    12061 actcaaaaaa gtaagtgaaa aagcaaccgc acctgcagtt gcttttatcg ttttcttatt
    12121 cttgatagcg tgttggtcct gcacttgcac tacggatatt caagcgtttc ttgagataga
    12181 agcgaagggc taggagagct gctccaataa tagctagtgg caatggatcc agtactgggt
    12241 taaggctagc tggtaggaag cttgttgcaa agaagacaag caaccaaagg aacatagaag
    12301 ctaggataac tagtacagat ttccagaaag gtggacgttg actgcgatcc atatctggtc
    12361 catagtattg gtaaacaaag tagtacatca agtagaaggc aaatccacca accagtccaa
    12421 ctaatagaag agtaatcaat ccatagccga aagcttgatc tgccgcaaag aaggttgtga
    12481 gggcgctgac aagggcaaag aggctagtga tgaaaagagc tgagtccata atcatcagtt
    12541 ttgggtcatc attttctttt ggatgctctt tttcgtactg ctctttgaca gtgaagctat
    12601 gagcccaatg agttggtgcg ccgtataggg aacgggcagt tgtaccttta gattgctcct
    12661 caaggatttg gggaatgact tcctcaaaaa tagtctggat ttcagcgtct gttttcccat
    12721 ctttgatgaa ttgttgggta gcaatgtgga caaactcttg gtttttctta gttaattttt
    12781 gtagatcaat ttgagacata ggaactcctc ttagaaccat tttttatgga tgagatagag
    12841 agtgagcgag acactcatag caaaggcgat aaagacgatt aaccagaagg catttggctc
    12901 tccgtttagg ggaatttcat tatccttaaa gttcatcccg taggcagaaa agaccatggt
    12961 tgggatggac atgacgatgg tcacaagggc caaggttttc atgatgttgt tctggttgtt
    13021 agaaatgata gaggcaaagg tctctgtcat agaatgcaag acgtttccat aaatatctgc
    13081 catctcgatg gcctgttggg tttcaatcag ggtgtcttca agcaggtctt cgtcctcaag
    13141 gtatttcttg atattgctgg ttgaactggt caatttctta atcacgcgct catttgtttt
    13201 gagggaggcc ttgaaataga cgatagtttt ttccaattcc atgagctcaa tcaattcttc
    13261 attacgagtt gattgatgca gttgactttc gatttgttca ctcttgcggt cgattgaacg
    13321 aagggctgtt aggtaaagct ctgcattgcg ataaagaatt tgaaagataa aacgtgaacg
    13381 catgaaggta tagaaattac gcaatcgacg gttgataaag acatcaagga caggtagtgg
    13441 ttccaaacac gtagtgataa tggtttcctc agtgatgata ataccaagcg ggatggttac
    13501 gtagtaggtg cggttatttc tttcctccgt gaccggcacg tctacgataa tcagggtata
    13561 ctcgtcttca atggtaatac gagacatttc ttccgcatcg agcggtgctc gaaggtcggc
    13621 aatatcaata tcgaaggtgt tggcgatttc gagtgattca ttttgagtcg gattgacgag
    13681 attgatccaa gtacccggtt caagcgtatc gatctcttta aattcagttg ttgtagagag
    13741 aaaaacttgt ttcatatccc ttatcctttc tcatttttca gattttttca cactgtacta
    13801 ttatactaca aaatcggcct tttgggtaat agaatctcac tttttttggt ataatggtaa
    13861 gcaataatgg actagaaaga acaaagatgc aagataaaat tgtcattcat ggggcgcgtg
    13921 cccataattt aaaaaatatt gatgtggaga ttccgcgaga caagttggtt gtcgtgactg
    13981 gcttgtcagg ttcagggaag tccagtctgg cttttgatac tctctatgcg gagggacaac
    14041 gtcgctatgt agagagtttg tctgcctacg ctcgtcagtt cttgggaaat atggaaaaac
    14101 cagatgtaga tgccattgat ggtctcagcc cagctatttc catcgaccag aaaacgacta
    14161 gtaaaaatcc tcgctcgacg gtgggaacga cgactgaaat caatgactat ctgcgtctcc
    14221 tctacgcacg tgtggggacg ccttactgta tcaacggaca tggagctatc aatgcttctt
    14281 ctgtggagca aatcgttgat aaggttttgg agttacctga acgccagcgc ttgcagatct
    14341 tggctcctgt catccgcaag aaaaaaggcc aacataagag tgttatcgag aaggttcaga
    14401 aagacgggta tgttcgtgtt cgtgtggatg gggaagtcta tgatgtgacc gaagtgccag
    14461 agttgtctaa gagcaagcaa cacaatatcg atgtcgtggt tgaccgtatt gttatcaagg
    14521 agggcattcg tagccgtctc tttgattcca ttgaagctgc ccttcgtatc gcagaaggtt
    14581 atgtgattat cgacaccatg gacgactctg agttgttgtt ctctgagcat tatgcctgtc
    14641 cagtttgtgg atttactgtc ccagagttag aacctcgtct cttctctttc aatgctccct
    14701 ttggctcttg tagtgagtgt gacggcttgg ggatcaagct ggaggtagat actgatttgg
    14761 tagtgccaga tgccagcaaa accttacgtg agggagcgct agcaccttgg aatcctatct
    14821 catccaacta ctatccaaac atgttagagc aggccatgaa agtctttgga gtggctatgg
    14881 ataagccttt tgaggacctg tcagaagaag ataagaactt gattctctat gggtcagatg
    14941 gtaaggaatt ccatttccac tatgagaatg aatttggtgg cgtgcgcgat atcgacattc
    15001 cgtttgaggg agttatcaat aatatcaaac gtcgttacca tgaaaccaat agcgattaca
    15061 ctcgcactca gatgcgtctc tacatgaatg agctgacctg cggaacctgt caaggctatc
    15121 gtctcaatga ccaggccttg tctgtccgtg tgggcggcca gcaagggcca catattggag
    15181 aaatctcaga cctgtctatc gctgaccact tggacttggt gagccagtta actttgtctg
    15241 aaaatgaagc catcattgct cgtcccattc tcaaggaaat caaggatcgt ttgaccttcc
    15301 ttaataatgt gggtcttaac tatctaaccc tgtcacgttc agcaggaacc ctttcaggtg
    15361 gggaaagtca gcgcattcgt ttggcaaccc agattggttc caacctatca ggcgtcctct
    15421 atatcctaga cgagccgtca atcggtcttc accagaggga caatgaccgc ctgattgcca
    15481 gtctgaaaaa gatgcgtgac ttgggcaata ctcttatcgt ggtggaacac gacgaagata
    15541 ccatgcgtga agctgattat ctgattgacg ttggtcctgg tgccggtgtt tttggtggtg
    15601 agattgttgc agcaggtaca cctaagcaag tggctcgcaa cagcaagtct atcacaggtc
    15661 agtacttgtc aggcaaacgt gtcatcccag taccagaaga gcgccgtgtc ggaaatggtc
    15721 gttttattga agtgacagga gcgcgtgaga acaacttgca aaatgtcacg gctcgctttc
    15781 cactaggaaa atttatcgca gtgacaggtg tgtcgggttc agggaaatcg actctaatca
    15841 acagcattct caaaaaagcc attgcccaga agctcaaccg taattcagac aaacctggta
    15901 agtttaagac tattacaggg attgagcatg tcgaccgttt gattgatatt gaccagagcc
    15961 ctatcggacg gacgccgagg tctaacccag ctacctatac aggagttttt gacgatatac
    16021 gtgacctttt tgctcagaca aatgaagcca agattcgagg ctacaagaag gggcgcttca
    16081 gtttcaacgt caagggaggt cgctgtgaag cttgctcagg tgacgggatt atcaagattg
    16141 agatgcactt cttgccagat gtttatgtgg cttgtgaagt ttgccacgga acccgctata
    16201 acagtgaaac cctagaagtt cactacaagg aaaagaatat ttcgcaggtc ttggatatga
    16261 cggtcaacga tgcggtagaa tttttccaac acattccgaa aattcaacgc aaactccaga
    16321 ccatcaagga tgtagggcta ggctatgtga ccttgggaca gccagctacc accctttctg
    16381 ggggagaagc ccaacgtatg aagttagcta gcgaactcca caaacgctcg acaggaaaat
    16441 ctttctacat tctggatgag ccgacgacag ggcttcatac agaggacatt gctcgcctgc
    16501 tcaaggtttt agctcgcttt gtagacgatg gcaatacagt cctcgtcatc gagcacaatc
    16561 tggatgttat caagacggca gaccatatca ttgacttggg acctgagggc ggtgtcggtg
    16621 gtggaaccat catcgtaaca ggaactccag aagaagtagc tgccaacgaa gccagctata
    16681 caggacacta tttgaaagga aagttacatc atgaataaac gcgtacaagc atttctagct
    16741 aaaatgcaag aaaaagaact agatggtatc atcatcaaca atcttaaaaa cgtctattat
    16801 ttgactggtt tttggggctc aaacggaaca gtctttatca gtcgtgaccg tcaggtctta
    16861 gtgacagact ctcgctatat catcgcagct aagcaagaaa ccagtggttt tgagattgtg
    16921 gctgatcgtg atgaattggc tgtcattgca ggaattgtta aggacatggg cttgactcgt
    16981 atcggttttg aagatgagat ttcagtgtct tattaccacc gtatgcaggc agcttttgca
    17041 ggtttggact tgtttccgca aactcagttt gtggaaggtc ttcgtatgat taaggatgag
    17101 gcagagattg cagcgattcg caaggcttgt tctatctcag accaagcttt ccgcgatgcg
    17161 cttgacttta tcaaaccagg aaaaactgaa attgagattg ccaacttcct tgacttccgc
    17221 atgcgtgagt tgggagcatc tggcttatct tttgatacga tcctagctag cggtatcaat
    17281 tcttctaaac cccatgccca tccaatgcac aaaccagtgg agttgggaga agccattacc
    17341 atggacttcg gctgtctcta tgaccactat gtcagtgata tgacccggac tatctatcta
    17401 gggcatgtta gcgatgagca ggcagagatt tacaatacgg ttctaaaagc taaccaagcc
    17461 ttgattgacc aagctaaggc aggcttaggt ttccgtgact ttgacaaaat ccctcgtgat
    17521 attatcattg aggcaggtta tggcgactac tttactcacg gcattggcca cggtattggt
    17581 ctggatatcc atgaggaacc ctactttagc cagacttcta cagaaactat taagacaggt
    17641 atggccttga ccgatgaacc aggtatctat atcgaaggca aatatggcgt tcgtatcgag
    17701 gatgatatcc tgattacaga gacaggttgt gaattattga ccctagctcc aaaagagttg
    17761 atagtcattt agttgtttgt caagaaaaaa gtacgaaaat gacgaaaaaa gtcaaaaaaa
    17821 attaaaaata ggtcgcaagt cggatgtttt ttatggtata atagactaaa ctgatagtaa
    17881 catgtagcga aaggggtagg tacatgatta aaatttatac agtctcaagt tgtactagct
    17941 gtaaaaaagc aaaaacctgg ctcaatgccc accagttaag ttataaagaa caaaaccttg
    18001 gtaaagaagg aattacgaga gaagaattac tggatattct aaccaaaaca gataacggaa
    18061 tagccagcat cgtttcgtct aaaaatcgct atgccaaagc ccttggagtg gatattgaag
    18121 atttgagtgt caatgaagtt ctcaatctga ttatggaaac accgagaatt ttaaagagcc
    18181 caatccttgt agatgaaaaa cgcctgcaag ttggctacaa ggaagacgat attcgtgcct
    18241 tcctaccacg ctctgtccgt aatgtagaaa atgcagaagc acgtttacgt gcagctctat
    18301 aaacatcaag gctgggagca attcccagtc ttattctatt ttaatttcaa aaagaaagaa
    18361 gaaagaaatg aaaaaaatag ttcttgttag tctagctttc ctttttgtcc tggttggttg
    18421 cggacagaaa aaagaaactg gaccagctac aaaaacagaa aaggatacgc ttcagtcggc
    18481 attgccagtt attgaaaatg ccgagaagaa tacagttgta accaagactt tggtcttgcc
    18541 caagtcagat gatggtagcc agcaaactca aaccattaca tacaaggaca agactttttt
    18601 gagcttaacg attcaacaaa aacgtccagt ttctgatgag ttgaagactt atattgacca
    18661 acatggagtg gaagaaactc aaaaagctct tcttgaagcg gaggagaagg ataagtctat
    18721 cattgaagct cgtaaattgg taggtttcaa acttgaaaca aaactattga gcgcaacgga
    18781 acttcaaaca acgactagtt ttgattttca agttctggat gtcaagaagg cttcccagtt
    18841 ggaacatctg aagaatattg gtttggaaaa tcttttgaaa aatgaaccaa gcaaatatat
    18901 ttcagacaga ttggcaaatg gtgcgacaga acagtagaaa atccaaataa atagactgcc
    18961 tgaattgtag aaggtaagga attatgctat aatggtacta ttctaaggaa agagggtgtt
    19021 agaatgggat ttactgaaga aacagtacgt tttaaattgg acgattccaa taaaaaagaa
    19081 attagcgaaa ctttgacaga tgtttatgct tcgttgaacg ataagggtta caacccaatt
    19141 aaccaaatcg taggttacgt attgagtgga gaccctgcct acgttcctcg ttataataat
    19201 gcacgaaatc aaatccgtaa gtatgagcgt gatgaaatcg ttgaggaatt ggttcgctac
    19261 tacctcaaag gacaaggagt cgatctataa cctatgagaa ttatgggatt ggacgtcggt
    19321 tcaaaaacgg taggggtggc gattagcgat ccgcttggtt ttacagctca agggcttgaa
    19381 atcatccaga taaatgaaga acaaggccaa tttggttttg accgcgttaa ggaattggtt
    19441 gatacttaca aggtggaacg atttgtagtg ggcttgccta aaaacatgaa caatacaagt
    19501 ggaccgcgcg tagaagctag tcaagcctac ggagcaaagc tagaagagtt ttttggttta
    19561 ccagtagact atcaggatga acgcttgaca acagtggctg ctgagcgcat gttgattgaa
    19621 caagcagata tcagtcgcaa taagcgcaag aaagtcattg ataagttagc agctcagctg
    19681 attttacaaa attatttaga tagaaaattt taatataaag gagaggctat gtcacacgat
    19741 cataaccacg accacgaaga acgtgaacta atcacactag tagatgagca aggaaatgaa
    19801 accttgtttg aaatcctttt gacaattgat ggaaaagaag aatttggtaa aaactatgtt
    19861 cttctagtac cagttaacgc agaagaagac gaagacggac aagttgaaat ccaagcttac
    19921 tcattcatcg aaaacgaaga tggaacagaa ggcgaattgc aaccaatccc agaagactca
    19981 gaagacgaat ggaacatgat tgaagaagtc ttcaacagct ttatggagga gtgatacagt
    20041 ctgggagact gtatcagccc aactcccaga aatggggaag agttggaacg tccagtggat
    20101 gtttttagcc cagttccttt aaataagaga gaactggtag gttcgggggg acgtttttag
    20161 cccagctcct ttaaataaga tagagctggt aagtctggga gactgtatca gcccaactcc
    20221 cagaaatggg gaagagttgg aacgtccagt gaacattttt accccaactc ttagaaattg
    20281 agaagagttg gaacatctag tggatgtttt tagcccatat tcacattcat agtggctagt
    20341 tattagctaa ccaggtaaga ggtcgggacg aaaatcctgg ccttgttttt attagtaacc
    20401 atactttaat gcgataattg attggacttt tgtcaaggag atgtgtatgt ttgaagtaga
    20461 agaatggctc catagtcgga ttggtttaaa ttttcgatca ggtttgggcc gaatgcagca
    20521 agcggtggat ttgttaggaa atcctgagca gtcttaccct attatccacg taacagggac
    20581 taatgggaaa ggatctacca ttgcttttat gagggaatta tttatggggc atggcaaaaa
    20641 agttgcgacc tttacctccc ctcatatcgt ctctatcaat gaccgaatct gcattaatgg
    20701 gcaacctata gcagacgcag actttatccg tttggctgat caggtcaagg agatggagaa
    20761 aacgcttctg caaactcctg accagttgtc cttttttgaa ttgctgacct tggttgcttt
    20821 tctttatttt agggagcaag aggtggattt ggttttatta gaagtgggaa ttggtggctt
    20881 acttgacacg accaatgtgg taactggaga gcttgctgtc atcacctcca ttgggcttga
    20941 ccatcaagaa accttgggtg atagtctaga agcaattgca gagcagaaag ctggtatttt
    21001 caaggctggt aagaaggcag tgattgcgaa attgcctcca gaagctaggc ttgtctgtca
    21061 gaaaaaagcc gaatctttag ctgttaacct ttatcaggca ggtcaagatt ttttaatgct
    21121 gaatggtgat ttttcaagct ctttactaaa tctttcacag ctgaacatag gcttagaagg
    21181 agtctatcag caggagaatg cagccttggc gttgcaaact tttcttcttt ttatgggaga
    21241 aggaaaggaa gctgttgatg aacaggctgt aagaaaggcc ttggaacaga cccattgggc
    21301 tggtcgcttg gagcgtattc gcccacagat ttacttggat ggtgctcata acctccctgc
    21361 cttgactcgc ttggttgagt ttatcaaaga aaaagagcag gaaggctatc gacctcaaat
    21421 cctttttgga gccttgaaac ggaaggatta tcaagggatg ttaggttacc tgactgaaaa
    21481 attgcctcag gtggaactca aggtgaccgg ctttgactat cagggggctt tggacgaaag
    21541 ggatgtgaca ggttacgata tagtttcttc ttgccgagaa tttatcagcg attttgaaga
    21601 aagagcagat gctcaggatt tgctgttcgt tacagggtct ctctatttta tctcagaagt
    21661 acggggctac ctgctggacc gtgagcagat aaattgaccc ccttgtttga acttgttata
    21721 ctaggggaat tgctggttag agaaaatttc tctaaattgg tagcagaaag gaaattcatc
    21781 atgaaattaa aaagattcac actttctctt gcttctctag caagttttag tctcttagta
    21841 gcttgttcac aaagagctca acaggttcaa cagcctgttg ctcagcagca ggtccaacag
    21901 cctgctcaac aacctgctca acagaatacc aatactgcaa atgcaggagg taaccaaaat
    21961 caagcggctc cagtacaaaa ccaacctgtt gctcaaccga ccgatattga tgggacttat
    22021 actggtcagg atgacggaga ccgtatcact ttagtggtaa ctggaacgac tggtacatgg
    22081 actgagctcg aatctgacgg ggatcagaaa gtcaaacagg ttacatttga ttcagcaaat
    22141 caacgcatga ttattggcga tgatgtcaaa atttacactg taaacggtaa tcaaatcgtc
    22201 gtagatgata tggatagaga cccatcggac caaatcgttt taactaaata agactatgca
    22261 agtagaaagg gctggatttt tcagcctttt tacttttacc tagaaaataa tcataaatac
    22321 ttgccttcta ccgaatacct gcgttatact agtatcaatt acttgttttt agcattcaaa
    22381 ctatcaagga ggggatatga aatataggaa atttcaatta ttgatgtcca agtatggctt
    22441 tagtctttcg attatgttac ttgaactttg tcttgttttt ggtctctttc tttatttagg
    22501 acgcatggct cccattttat ggattactgt cctcattcta ctgagtatca tcacaatcat
    22561 ttcgatagtc aaccgtaata cgactcctga gaataaggta acctggttgt tagtagcctt
    22621 tgtgccagta tttggtccct tgctctatct gatgtttggt gaaaggcgat tgtccaaaaa
    22681 agaaatcaaa caactgaaga agctaggctc tatgcatttc caagaagcaa atagccagct
    22741 actaaaagag aaattaaaag aaagtgacaa ggcagcttat ggagtcatca agtccttatt
    22801 gagtatggat accaatgctg acatctatga tcaaactgcc tctacatttt ttcctaacgg
    22861 agaagctatg tggaaaaaga tggtagaaga tcttaaaaag gctgagaaat ttattttctt
    22921 ggaatattac attatagaag aaggtttgat gtggaatcgc atactagata tactagagca
    22981 aaaggtagct cagggtgtag aggttaagat gctctatgat gatatcggct gtatggctac
    23041 tttaacagga gattatgcac atcgacttcg tcagctgggc atcgaggccc ataaattcaa
    23101 taaagttatt cctcgtttga cagtggctta taataacaga gatcatagaa aaatattgat
    23161 tgttgatggt cagatagcct atactggtgg gatcaatctg gcagatgagt acattaacca
    23221 cgtcgagaga tttggttatt ggaaggatag tggaattcgc ttagacggac tagcagtaaa
    23281 agctctgaca cgcttatttt tgaccacttg gtacattaat cgaggagaaa ttagtgattt
    23341 tgatcaatat catttagaaa atcattctat cccgagtgac ggtttaacca ttccatacgg
    23401 aagtggaccc aagccaattt ttcgagcgca ggtagggaaa aaagtttatc agagtttaat
    23461 caatcaagca acagaatcgg tctatattac gacaccttat ttgattatag attatgattt
    23521 aacagagaca atcaaaaatg cagctatgag aggggtcgat gttcgaatta tcacccctta
    23581 cataccagat aagaagttca ttcagttagt cacgagagga gcttatcccg accttctttc
    23641 tgctggtgtt cggatttatg agtatagtcc aggttttatt catagtaagc agatgttggt
    23701 agacgaagat tttgcggtgg tggggacaat caatctcgac taccggagct tggtacacca
    23761 ttatgaaaat gcagtcttac tctataaaac tccttctata agggaaatcg cccgagattt
    23821 tcgaaatata tttgcagatt ctcaggaagt ctatcctcat tctatcaaaa cgagctggta
    23881 tcaaaagctt gtaaaagaaa tcgcccagct attcgcccct atcttataag aaatctagaa
    23941 cttaggatac aaaccagacc tatttttctt gtcttttacg aatagaaaga aagaggaggg
    24001 gaattcatgc taactaagga agaagtgaat gatatgattg agttcaaaca gacacattta
    24061 caccgctttc gggaaattga aacctttgtg aaactatgca aaaaatcact caaacagcca
    24121 tcgcaagctg acaatcctag gactttttga tatactaaga cagataaatt gaacaggaga
    24181 aacgatatga gtgtgtatgg tagagtagaa gaagttcata aggagaatcg tgaacctcta
    24241 gaataccaaa tcgaacaaga atcgcatcat cgtgaatcaa gtcgtcttcc tttggtgaaa
    24301 attttactat ggagtacgct tgtaacgggg ataactctag gagtaccgct attactcgac
    24361 ttaatgagtg cacaagaagt gcaggatttt tatgcaggtt gggcgcttca tcagacaggg
    24421 aagatttaca gcgactatta tggaagtcaa ggtttgcttt attatttgct gacttacgtg
    24481 agtcagggcg gatttttctt tgccatcttt gagtggttag ccttggtagc aggaggattt
    24541 ttccttttta gatcagcgga caccttgaca gagcaaggag accaagctgg acatctggtg
    24601 actatttttt acatgctagt tacaggtctt gcttttggtg gaggctatgc gactctttta
    24661 gcgcttcctt tcttattcgc agcctttagt ttagttgcgg cttacctaag caatccaagc
    24721 catgataagg gatttgtacg gattgggcta gctttggcag gcggattttt ctttgctccc
    24781 ttatcatcgc tcctgtttat tgctgtagtg agtttaggct tgttggtctt taaccttggg
    24841 catagacgct ttgcgcatgg gttttatcag tttcttgcag tggctttagg tttttcactt
    24901 gtcttttatc caactgccta ctatagtgct gcaacaggaa gttttgggga tgcgattagt
    24961 ggtattcgtt atcctattga cagtattcgc tttgatttta cttctaaaat tttagagaat
    25021 atgttttttt atggcttgtt gtcccttggt ttgggatttg tggtttgtat ctttttaggt
    25081 ctctttcaat ccaaaccctt taaactatac gtcatttcgg ttcctgcaag tcttgtggta
    25141 attttaggtt tgattttact tttcttttca caagagcctc tgcacgcttc ttatttgatg
    25201 gtcgtcttcc ctgttttcct acttttattg gtaaccaata ttaagagtca acagaggggg
    25261 cgtagtgcta gaagaagccg aagagaaacg ccagttagcc tatggagtcg tttcttcaaa
    25321 ggaaatctat atctgctagt ttttgagttt gtctatcttt tgtctgttcc ttttttgatg
    25381 aagtttgtcc tttatccagt accttatcaa gaacgtaatc gtcttgctga tttggtaaaa
    25441 gaggagacaa atacggaaga tgctatctat gcatgggatg atactgcgac tctttatcgt
    25501 aagagtgagc gcttgtcgcc atcggcgatt ttgtccccgt tgcactatac agcaactgag
    25561 gaaaatcgta ataagttact taatgacttg aaagaaaaac aacctaaggt gattgtggta
    25621 aatgataagg tggtagtctg gtctgaagtg gaaacactct taaaagaaaa ttaccaacaa
    25681 gtaaagactg attactcaga gtttaaagtc tataaaatta aataaccaaa tcaatatctt
    25741 gtgtattttt aaaaatttta ggatttttaa cacaagatat tgatttttct ttttagagtg
    25801 gtataatact ttttagaaag aacattttag aaaagagcat gcatatgatt gcactagaag
    25861 aaaaaattac aattttgcca actctcttcg tcgagaaacg agatgggaga cgtgttgtat
    25921 ttgatgtgga caagattgac aaggctctcc acaaggcggc tgacaaggtt atggatgtga
    25981 cacccctggt tgaaaaacgc ctcaatgatc tgactgagcg aattattaca gaaattcata
    26041 gtcgctttcc acagggaatt aagatttacg aaattcaaaa tatcgtagaa catgaactcc
    26101 ttgaagccaa agaatatgcg ctggctgagg agtatattac ttatcggaca cagagggatt
    26161 ttgagcgctc aaaagcgacg gatatcaact ttagtattca taaacttctc aacaaagacc
    26221 agacagttgt caatgaaaac gctaataaag acagtgatgt ctttaacact cagcgtgatt
    26281 tgacagcagg gattgttggg aaatcaatcg gactgcaaat gcttcctaag cacgtagcca
    26341 atgcccacca aaagggggat atccactatc acgatttgga ctacagtccc tataccccta
    26401 tgaccaactg ctgtttgatt gattttaagg gtatgttgga aaatggtttt aagattggaa
    26461 atgcagaggt agagagtccc aagtctatcc agactgcgac agcacagatt tctcaaatca
    26521 ttgccaacgt tgcttctagc cagtacggtg gctgttcagc tgaccgtatc gatgaaattt
    26581 tggcgcctta tgcagagaag aattatcaaa aacatctcaa agatgcagaa gagtgggtat
    26641 tgcctgaaaa acgggaagat tacgcttgga agaaaacgca aaaggacatc tacgatgcca
    26701 tgcaatctct tgagtatgaa atcaatactc tcttcacttc aaatggacaa acacctttta
    26761 cttcgttagg ttttggtctg ggaaccagtc gttttgaacg agaaattcaa aaagctattt
    26821 taaacattcg catcaagggt cttggttcag aacaccgtac ggctatcttt cctaaactta
    26881 ttttcactct gaaaagaggc cttaatttag aggaaggaac tcccaactac gacatcaagc
    26941 agttggctct tgagtgtgca accaaacgga tgtatccaga tgttttatct tacgataaga
    27001 ttgttgactt gacaggatcc ttcaaggtgc ctatgggttg ccgttctttc ctccaaggat
    27061 ggaaggatga aaatggtgta gaagtcaatt caggtcgcat gaatctgggt gttgtgacgg
    27121 ttaatctgcc tcgtattgct cttgagtctg aaggtgatat gaataagttc tgggaaatct
    27181 tcaacgagcg aatgaatatc gcagaagatg ctcttgttta ccgtgtcgaa cgcactaaag
    27241 aggcgacacc agcaaatgct cctattcttt atcagtacgg tgcttttggc catcgtctag
    27301 gtaaagaaga aagtgttgac cagctcttta agaatcgtcg tgctaccgtt tcgctgggct
    27361 atatcggctt gtatgaagta gcgacagttt tctttggtaa cagctgggaa agtaatccag
    27421 atgctaagga attcacgcta gacatcattc acgatatgaa acgccgtgta gaagagtggt
    27481 cagaccaata tggctaccat ttctctatct actcaacacc atccgaaagt ctgacagacc
    27541 gtttctgccg actagatata gacaagtttg gctctattcc tgatatcaca gacaaggaat
    27601 actacaccaa ctctttccac tacgatgttc gtaaaaatcc aacaccgttt gaaaaattgg
    27661 actttgagaa agtctatcca gaagcaggtg cgtcaggtgg tttcatccat tattgtgagt
    27721 atccagtcct tcagcaaaat ccaaaggcct tggaagctgt ctgggattat gcttatgacc
    27781 gtgtaggcta tctaggcacc aatactccga ttgaccgttg ctacaagtgt gactttgaag
    27841 gggattttga accaactgag agagggtttg cttgtccaaa ctgtggcaat agcgacccta
    27901 aaacagtaga tgtggtgaag cgaacttgtg gctacctagg taatcctcaa gcaagaccga
    27961 tggtcaacgg gcgtcacaag gaaatcgctg cgcgtgtcaa acatatgaat ggttcaacga
    28021 ttaaaatagc tgggcatcaa gtaacaaatt agaaagaaat gaaatgggaa aatatcaact
    28081 agacgataag gggcgcgcac aagtgacccg ttatcacgag aaacactcta aaggtggagc
    28141 tggtaagaaa gaacgcttgc ttagcttcag agaacaattt ttaaacaaga acaagaaaaa
    28201 ataaaagtga gagccagctc tcgcttttct catagtggga ggtaaggatg gaattacgca
    28261 gaccaagatt agcggataag aaagctgttt tagatatgat gacagagttt gaaaagagtc
    28321 aatcagccca tgatggagga ttttgggatg ttgaggattt ttcttacgag gagtggctag
    28381 aaggtaaccg taataaagaa atgggaatat ggctacctga aaatcgcgtt ccatcgatac
    28441 agttcgtatt gtttggtgaa tcaggttgtg ctctaggatt tttgaatctg cgattgagac
    28501 tgaatgaggg gttactgaat tatgctggcc acattggcta ctccatccgt ccatctgaaa
    28561 gaggcaaggg ttatgcaaaa gagactctcc gtcagggctt gcaagttgct aaggaaaaga
    28621 acatcaagaa agctctggtg acctgtagcg tgaataatct tgctagcaga gcagtcattc
    28681 tagcaaatgg tggaatattt gaggatgctc gcaatggagt cgagcgttat tggatagagg
    28741 tagcgaatga ataatccaaa accacaagaa tggaaaagcg aggaacttag tcaaggtcgt
    28801 atcattgact acaaggcctt taactttgtg gacggcgaag gcgtgcgtaa ctctctctat
    28861 gtatcaggct gtatgtttca ctgcgaggga tgttataatg ttgcgacttg gtcttttaat
    28921 gctggcattc cctatacagc agaattagaa gagcagatca tggcagatct tgctcagccc
    28981 tatgttcaag gtttgacttt gttgggaggg gagccttttc ttaatactgg gattctcttg
    29041 ccacttgtta agcggattcg gaaggaattg ccagacaagg acatctggtc ctggaccggc
    29101 tacacttggg aagaaatgat gttggaaact ccagataaac tggaattctt gtcactgatt
    29161 gacattcttg tcgatggaag atatgatcga actaagagaa atcttatgct ccagtttcga
    29221 ggttcgtcta accaacgaat tatcgatgtg caaaaatcgc tcaaaagtgg gcaagtagtg
    29281 atttgggaca agctcaatga cggaaaagaa agctatgaac aggtgaagag agaatgaaga
    29341 aaaaagactt agtagaccaa ctagtctcag agatcgagac ggggaaagtc aggacactgg
    29401 gaatatacgg tcatggagct tcaggtaaat caacctttgc acaggaattg taccaagctt
    29461 tagattctac tacagtaaat ttgctagaga cagatcctta tatcacctca ggacgccatc
    29521 tggtagtacc caaggacgcg ccgaatcaaa aggtgacagc cagtctgcca gtggcgcatg
    29581 aactggagag tttgcagaga gatatccttg ccttgcaggc gagtatggat gtcttgacaa
    29641 ttgaagaacc ttggaaggct agtgaggtct tgtctggagc caaaccaatt ttgattgtcg
    29701 aagggatgtc tgttggcttt ctacccaagg aactctttga aaaaaccatc tgtttctaca
    29761 cggatgagga gaccgaatta aagcgacgcc ttgctagaga tacgactgtg agaaatcgcg
    29821 atgcatcctt tatattggct agccatcaga tgagacggga gcagtatctg cgatactata
    29881 aagaaactga gtctaaggcg gatatcttag tggaccaatc agaagataaa tttgatgtca
    29941 agaggactta acttatgtat agaagaaata tagaagaaaa tccctaattt tagaaagaaa
    30001 aagtaggaaa acagtttcat ccccaaaaaa cgaaaaaacc taacaaatcc cttgcaatcg
    30061 caggggattt gtgttattct attatggtgc tgtaaattac agccttagtt ttgatgcaag
    30121 aggttgcgac acgctcggtt gcattgccac gcaacaccgc gtcggttttc ttgtggagct
    30181 agcctattat cttaaataga cgaaaaggag aaaaagatgg caaacaaaaa aatccgtatc
    30241 cgtttgaaag cttacgaaca ccgtacgctt gacacagcgg ctgcaaaaat cgtagaatca
    30301 gctactcgta caggtgcaca agttgcgggt ccaatcccac ttccaactga acgtagcctc
    30361 tacacaatca ttcgtgcgac tcacaaatac aaagactctc gcgaacaatt tgaaatgcgt
    30421 acacacaaac gtttgatcga tatcgttaac ccaactcaaa aaacagttga tgccttgatg
    30481 aaattggatc ttccaagtgg tgtaaacgta gaaatcaaac tttaatctaa aatataaaag
    30541 agcagaggct ggtgtttcaa tctaattgaa cacgggctaa actcggtgtg aaaaagataa
    30601 acttcctcgc gtctgctaga cactgtgtca gtttcctatt ttcactttga gtttgacgcc
    30661 ctttgtatct tagacttgag cataaaaaac gctcgttaaa aactttttga ataaaaaata
    30721 tagaaaagga actattttct catgacaaaa ggaatcttag ggaaaaaagt gggaatgact
    30781 caaatcttca ctgaagctgg cgaattgatc cctgtaacag ttattgaagc aactccaaac
    30841 gttgttcttc aagttaaaac tgttgaaaca gacggataca acgctatcca agttggtttc
    30901 gatgacaaac gcgaagtatt gagcaacaaa cctgctaaag gacatgtagc gaaagctaac
    30961 acggctccta agcgcttcat tcgtgaattc aaaaacgttg aaggcttgga agttggtgct
    31021 gaaattacag ttgaaacatt cgcagctgga gacgttgttg acgtaactgg tacttctaaa
    31081 ggtaaaggtt tccaaggtgt tatcaaacgc cacggacaat cacgtggacc aatggctcac
    31141 ggttctcgtt accaccgtcg tccaggttct atgggacctg ttgcacctaa ccgcgtattc
    31201 aaaggtaaaa accttgcagg acgtatgggt ggtgaccgcg taacaattca aaatcttgaa
    31261 gttgtacaag ttgttccaga aaagaacgtt atccttatca aaggtaacgt accaggtgct
    31321 aagaaatctc ttatcactat caaatcagca gttaaagctg gtaaataata aagaaagggg
    31381 aaatcagtca caatggcaaa cgtaacatta tttgaccaaa ctggtaaaga agctggccaa
    31441 gttgttctta gcgatgcagt atttggtatc gaaccaaatg aatcagttgt gtttgatgta
    31501 atcatcagcc aacgcgcaag ccttcgtcaa ggaacacacg ctgttaaaaa ccgctctgca
    31561 gtatcaggtg gtggacgcaa accatggcgt caaaaaggaa ctggacgtgc tcgtcaaggt
    31621 tctatccgct caccacaatg gcgtggtggt ggtgttgtct tcggaccaac tccacgttca
    31681 tacggctaca aacttccaca aaaagttcgt cgcctagctc ttaaatcagt ttactctgaa
    31741 aaagttgctg aaaacaaatt cgtagctgta gacgctcttt catttacagc tccaaaaact
    31801 gctgaatttg caaaagttct tgcagcattg agcatcgatt ctaaagttct tgttatcctt
    31861 gaagaaggaa atgaattcgc agctctttca gctcgtaacc ttccaaacgt gaaagttgca
    31921 actgctacaa ctgcaagtgt tcttgacatc gcaaatagcg acaaacttct tgtcacacaa
    31981 gcagctatct ctaaaatcga ggaggttctt gcataatgaa tttgtatgat gttatcaaaa
    32041 aacctgtcat cactgaaagc tcaatggctc aacttgaagc agggaaatat gtatttgaag
    32101 ttgacactcg tgcacacaaa cttttgatca agcaagctgt tgaagctgct ttcgaaggtg
    32161 ttaaagttgc caatgttaac acaatcaacg taaaaccaaa agctaaacgt gttggacgtt
    32221 acactggttt tactaacaaa actaaaaaag ctatcatcac acttacagct gattctaaag
    32281 caatcgagtt gtttgctgct gaagctgaat aatctaagga ggaaatatcg tgggaattcg
    32341 tgtttataaa ccaacaacaa acggtcgccg taatatgact tctttggatt tcgctgaaat
    32401 cacaacaagc actcctgaaa aatcattgct tgttgcattg aagagcaagg ctggtcgtaa
    32461 caacaacggt cgtatcacag ttcgtcacca aggtggtgga cacaaacgtt tctaccgttt
    32521 ggttgacttc aaacgtaata aagacaacgt tgaagcagtt gttaaaacaa tcgagtacga
    32581 tccaaaccgt tctgcaaaca tcgctcttgt acactacact gacggtgtga aagcatacat
    32641 catcgctcca aaaggtcttg aagtaggtca acgtatcgtt tcaggtccag aagcagatat
    32701 caaagtcgga aacgctcttc cacttgctaa catcccagtt ggtactttga ttcacaacat
    32761 cgagttgaaa ccaggtcgtg gtggtgaatt ggtacgtgct gctggtgcat ctgctcaagt
    32821 attgggttct gaaggtaaat acgttcttgt tcgtcttcaa tcaggtgaag ttcgtatgat
    32881 tcttggaact tgccgtgcta cagttggtgt tgtcggaaac gaacaacatg gacttgtaaa
    32941 ccttggtaaa gcaggacgta gccgttggaa aggtatccgc ccaacagttc gtggttctgt
    33001 aatgaaccct aacgatcacc cacacggtgg tggtgaaggt aaggcaccag ttggtcgtaa
    33061 agcaccatct actccatggg gcaaacctgc tcttggtctt aaaactcgta acaagaaagc
    33121 gaaatctgac aaacttatcg ttcgtcgtcg caacgagaaa taatattaaa ctagtcgctt
    33181 aagcaactag taaatccgcc agctcggtag cgctccatag gagtgcaagc cgctgtggta
    33241 caacatttaa aggagaaaat ataaaaatgg gacgcagtct taaaaaagga cctttcgtcg
    33301 atgagcattt gatgaaaaaa gttgaagctc aagctaacga cgaaaagaaa aaagttatta
    33361 aaacttggtc acgtcgatca acgatcttcc caagtttcat tggttacact attgcagttt
    33421 atgacggacg taaacacgta cctgtttaca tccaagaaga catggtaggc cacaaacttg
    33481 gtgaatttgc accaactcgt acttacaaag gtcacgctgc agacgacaag aaaacacgta
    33541 gaaaataagg agaacataaa tggcagaaat tacttcagct aaagcaatgg ctcgtacagt
    33601 acgtgtttca cctcgtaaat cacgtcttgt tcttgataac atccgtggta aaagcgtagc
    33661 cgatgcaatc gcaatcttga cattcactcc aaacaaagct gctgaaatca tcttgaaagt
    33721 tttgaactca gctgtagcta acgctgaaaa caactttggt ttggataaag ctaacttggt
    33781 agtatctgaa gcattcgcaa acgaaggacc aactatgaaa cgtttccgtc cacgtgcgaa
    33841 aggttcagct tcaccaatca acaaacgtac agctcacatc actgtagctg ttgcagaaaa
    33901 ataaggaggt aaaatcgtgg gtcaaaaagt acatccaatt ggtatgcgtg tcggcatcat
    33961 ccgtgattgg gatgccaaat ggtatgctga aaaagaatac gcggattacc ttcatgaaga
    34021 tcttgcaatc cgtaaattcg ttcaaaaaga acttgctgac gcagcagttt caactattga
    34081 aatcgaacgc gcagtaaaca aagttaacgt ttcacttcac actgctaaac caggtatggt
    34141 tatcggtaaa ggtggtgcta acgttgatgc actccgtgca aaacttaaca aattgactgg
    34201 aaaacaagta cacatcaaca tcatcgaaat caaacaacct gatttggatg ctcaccttgt
    34261 aggtgaagga attgctcgtc aattggagca acgtgttgct ttccgtcgtg cacaaaaaca
    34321 agcaatccaa cgtgcaatgc gtgctggagc taaaggaatc aaaactcaag tatcaggtcg
    34381 tttgaacggt gcagatatcg cccgtgctga aggatactct gaaggaactg ttccgcttca
    34441 cacacttcgt gcagatatcg attacgcttg ggaagaagca gatactacat atggtaaact
    34501 tggtgttaaa gtatggatct accgtggtga agttcttcca gctcgtaaaa acactaaagg
    34561 aggtaaataa ccaatgttag tacctaaacg tgttaaacac cgtcgtgaat tccgtggaaa
    34621 aatgcgcggt gaagcaaaag gtggaaaaga agtagcattc ggtgaatacg gtcttcaagc
    34681 tacaactagc cactggatca ctaaccgcca aatcgaagct gctcgtatcg ccatgactcg
    34741 ttacatgaaa cgtggtggta aagtttggat taaaatcttc ccacacaaat catacactgc
    34801 taaagctatc ggtgtgcgta tgggatctgg taaaggggca cctgaaggtt gggtagcacc
    34861 agttaaacgt ggtaaagtga tgttcgaaat cgctggtgta tctgaagaga ttgcacgtga
    34921 agcgcttcga cttgctagcc acaaattgcc agttaaatgt aaattcgtaa aacgtgaagc
    34981 agaataagga gaaggcatga aacttaatga agtaaaagaa tttgttaaag aacttcgtgg
    35041 tctttctcaa gaagaactcg cgaagcgcga aaacgaattg aaaaaagaat tgtttgaact
    35101 tcgtttccaa gctgctactg gtcaattgga acaaacagct cgcttgaaag aagttaaaaa
    35161 acaaatcgct cgtatcaaaa cagttcaatc tgaagcgaaa taatagacta gggaaggaga
    35221 aatttcaatg gaacgcaata atcgtaaagt tcttgttgga cgtgttgtat ctgacaaaat
    35281 ggacaagaca atcacagttg tagttgaaac aaaacgtaac cacccagtct atggtaaacg
    35341 tattaactac tctaaaaaat acaaagctca tgatgaaaac aatgttgcca aagaaggcga
    35401 tatcgtacgt atcatggaaa ctcgcccgct ttcagctaca aaacgtttcc gtcttgtaga
    35461 agttgttgaa gaagcggtca tcatctaatc aaacctgaaa ggagaaaact gaaatgattc
    35521 aaacagaaac tcgtttgaaa gtcgcagaca acagcggtgc tcgcgaaatc ttgactatca
    35581 aagttcttgg tggttcagga cgtaaatttg caaacatcgg tgatgttatc gtggcatctg
    35641 taaaacaagc tactcctggt ggtgcggtta aaaaaggtga cgttgttaaa gcagttatcg
    35701 ttcgtactaa atcaggtgct cgtcgtgctg atggttcata catcaaattt gacgaaaacg
    35761 cagcagttat catccgtgaa gacaaaactc ctcgcggaac acgtatcttt ggcccagttg
    35821 cacgtgaatt gcgtgaaggt ggcttcatga agatcgtgtc acttgctcca gaagtacttt
    35881 aatttttagg aacaaactag tcccctagct tcaagctagg gtgcccttat gggcgtaaga
    35941 aaaatcaagg agaaacctaa tgtttgtaaa aaaaggcgac aaagttcgcg taatcgctgg
    36001 taaagataag ggaacagaag ctgttgtcct tactgccctt ccaaaagtaa acaaagttat
    36061 cgttgaaggt gttaacattg ttaagaaaca ccaacgtcca actaacgagc ttcctcaagg
    36121 tggtatcatc gagaaagaag cagctatcca cgtatcaaat gttcaagttt tggataaaaa
    36181 tggtgtagct ggtcgtgttg gttacaaatt tgtagacggt aaaaaagttc gctacaacaa
    36241 aaaatcaggc gaagtgcttg attaatcacg aaggaaagga gaagtataat ggcaaatcgt
    36301 ttaaaagaaa aatatcttaa tgaagtagtt cctgctttga cagaacaatt caactactca
    36361 tcagtgatgg ctgtgcctaa agtagataag attgttttga acatgggtgt tggtgaagct
    36421 gtatcaaacg ctaaaagcct tgaaaaagct gctgaagaat tggcacttat ctcaggtcaa
    36481 aaaccactta tcactaaagc taaaaaatca atcgccggct tccgtcttcg tgaaggtgtt
    36541 gcgatcggtg caaaagttac ccttcgtggt gaacgtatgt acgaattctt ggataaattg
    36601 gtatcagttt cacttccacg tgtacgtgac ttccacggtg tcccaacaaa atcatttgat
    36661 ggacgcggga actacacact tggtgtgaaa gaacaattaa tcttcccaga aatcaacttc
    36721 gatgacgttg acaaaactcg tggtcttgac atcgttatcg taacaactgc taacactgac
    36781 gaagagtcac gtgcattgct tacaggcctt ggaatgcctt ttgcaaaata atataggagg
    36841 taaatctaat ggctaaaaaa tcaatggtag ctagagaggc taaacgccaa aaaattgttg
    36901 accgttatgc tgaaaaacgt gctgcattaa aggcggcagg ggactacgaa ggtttatcta
    36961 aattacctcg caacgcctca ccgactcgtt tacataatcg ttgtagggtt acggggcgcc
    37021 cacattcagt ttaccgcaaa tttggtctga gtcgtatcgc ttttcgcgaa cttgcgcata
    37081 aaggtcaaat tcctggtgta acaaaagcat cttggtaatt taagatatca agagtgtcaa
    37141 aactccaagt aaaaatagga aacttgacga agaaactaaa gtttctagga aagtttatct
    37201 ttttcacaca gagtttagcc cgggttcaat tgggcttgcc aatttgaaca cgagctacag
    37261 ctttggcaaa aaagaccaat ttgctttgga gcattgcttc tgcattaaat tgtctatttt
    37321 tgctcgtgct gttacgctct ttgtatcatg tattaactag caagtgcaac ttgcaaacta
    37381 ctagtaagag gagaaaaaca aaatggttat gactgaccca atcgcagact tcctaactcg
    37441 tattcgtaat gctaaccaag ctaaacacga agtacttgaa gtacctgcat caaacatcaa
    37501 aaaagggatt gctgaaatcc ttaaacgcga aggttttgta aaaaacgttg aaatcattga
    37561 agatgacaaa caaggcgtca tccgtgtatt tcttaaatac ggaccaaatg gtgagaaagt
    37621 tatcactaac ttgaaacgtg tttctaaacc aggacttcgt gtctacaaaa aacgtgaaga
    37681 ccttccaaaa gttcttaacg gacttggaat tgccatcctt tcaacttctg aaggtttgct
    37741 tactgataaa gaagcacgcc aaaagaatgt tggtggtgag gttatcgctt acgtttggta
    37801 aaatcaagat acaaagctcg taaagaacaa agcaaaatta ggaagttgga gaagtttgtt
    37861 tacaaacaag ccaacttatc tattttgcac agttcttaga gcgtgttcag ttcagctctt
    37921 gaactaaata agtatctgaa ccccgtgaaa actggccgtt ctggcctgac aatttaacag
    37981 gagaaaataa acatgtcacg tattggtaat aaagttatcg tgttgcctgc tggtgttgaa
    38041 ctcgctaaca atgacaacgt tgtaactgta aaaggaccta aaggagaact tactcgtgag
    38101 ttctcaaaag atattgaaat ccgtgtggaa ggtactgaaa taactcttca ccgtccaaac
    38161 gattcaaaag aaatgaaaac tatccacgga actactcgtg cccttttgaa caacatggtt
    38221 gttggtgtat cagaaggatt caagaaagaa cttgaaatgc gtggggttgg ttaccgtgca
    38281 cagcttcaag gatctaaact tgttttggct gttggtaaat ctcatccaga cgaagttgaa
    38341 gctccagaag gaattacttt tgaacttcca aacccaacaa caatcgttgt tagcggaatt
    38401 tcaaaagaag tagttggtca aacagctgct tacgtacgta gccttcgttc accagaacca
    38461 tataaaggta aaggtatccg ttacgttggt gaattcgttc gccgtaaaga aggtaaaaca
    38521 ggtaaataat gttgagtggt tgatcatcaa ccaccaacct attttccaac tttgtgcata
    38581 gcacacgatt taaaactaaa gaggtgaaaa ctgtgatttc aaaaccagat aaaaacaaac
    38641 tccgccaaaa acgccaccgt cgcgttcgcg gaaaactctc tggaactgct gatcgcccac
    38701 gtttgaacgt attccgttct aatacaggca tctacgctca agtgattgat gacgtagcgg
    38761 gtgtaacgct cgcaagtgct tcaactcttg ataaagaagt ttcaaaagga actaaaactg
    38821 aacaagccgt tgctgtcggt aaactcgttg cagaacgtgc aaacgctaaa ggtatttcag
    38881 aagtggtgtt cgaccgcggt ggatatctat atcacggacg tgtgaaagct ttggctgatg
    38941 cagctcgtga aaacggattg aaattctaat aggaggacac tagaaaatgg catttaaaga
    39001 caatgcagtt gaattagaag aacgcgtagt tgctgtcaac cgtgttacaa aagttgttaa
    39061 aggtggacgt cgtcttcgtt tcgcagctct tgttgttgtt ggtgaccaca atggtcgcgt
    39121 aggatttggt actggtaaag ctcaagaagt tccagaagca atccgtaaag cagtagatga
    39181 tgctaagaaa aacttgatcg aagttcctat ggttggaaca acaatcccac acgaagttct
    39241 ttcagaattc ggtggagcta aagtattgtt gaaacctgct gtagaaggtt ctggagttgc
    39301 cgctggtggt gcagttcgtg ccgttgtgga attggcaggt gtggcagata ttacatctaa
    39361 atcacttggt tctaacactc caatcaacat tgttcgtgca actgttgaag gtttgaaaca
    39421 attgaaacgc gctgaagaaa ttgctgccct tcgtggtatt tcagtttctg atttggcata
    39481 agaaagggga taaaatggct caaattaaaa ttactttgac taagtctcca atcggacgca
    39541 ttccatcaca acgtaaaact gttgtagcac ttggacttgg caaattgaac agctctgtta
    39601 ttaaagaaga taacgctgct atccgtggta tgatcacagc agtatctcac ttagtaacag
    39661 ttgaagaagt aaactaatga agttttaggg gatgtgcact gtaccatccc ctaaaactag
    39721 atatagtcat ctatgatgac atcgtatagg cgagttgatg ggggagacaa ccttttctcc
    39781 cttatcggcg ctagcatttt acaaaagagg agaaaataaa aatgaaactt catgaattga
    39841 aacctgcaga aggttctcgt aaagtacgta accgcgttgg tcgtggtact tcatcaggta
    39901 acggtaaaac atctggtcgt ggtcaaaaag gtcaaaaagc tcgtagcggt ggcggagttc
    39961 gccttggttt tgaaggtgga caaactccat tgttccgtcg tcttccaaaa cgtggattca
    40021 ctaacatcaa cgctaaagaa tacgcaattg tgaaccttga ccaattgaac gtctttgaag
    40081 atggtgctga agtaactcca gttgttctta tcgaagcagg aattgttaaa gctgaaaagt
    40141 caggtattaa aattcttggt aacggtgagt tgactaagaa attgactgtg aaagcagcta
    40201 aattctctaa atcagctgaa gaagctatca ctgctaaagg tggttcagta gaagtcatct
    40261 aagagaggtg acctatgttt tttaaattat taagagaagc tcttaaagtc aagcaggttc
    40321 gatcaaaaat tttatttaca atttttatcg ttttggtctt tcgtatcgga actagcatta
    40381 cagttcctgg tgtgaatgcc aatagcttga atgctttaag tggattatcc ttcttaaaca
    40441 tgttgagctt ggtgtcgggg aatgccctaa aaaacttttc gatttttgcc ctaggagtta
    40501 gtccctatat cactgcttct attgttgtcc aactcttgca aatggatatt ttacccaagt
    40561 ttgtagagtg gggtaaacaa ggggaagtag gtcgaagaaa attgaatcaa gctactcgtt
    40621 atattgctct agttctcgct tttgtgcaat ctatcgggat tacagctggt tttaatacct
    40681 tggctggagc tcaattgatt aaaactgctt taactccaca agtttttctg acgattggta
    40741 tcatcttaac agctggtagt atgattgtca cttggttggg tgagcaaatt acagataagg
    40801 gatacggaaa cggtgtttcc atgattatct ttgccgggat tgtttcctca attccagaga
    40861 tgattcaggg catctatgtg gactactttg tgaacgtccc aagtagccgt atcacttcat
    40921 ctatcatttt cgtaatcatt ttgattatta ctgtattgtt gattatttac tttacaactt
    40981 atgttcaaca agcagaatac aaaattccaa tccaatatac taaggttgca caaggtgctc
    41041 catctagctc ttaccttccg ttaaaggtaa atcctgctgg agttatccct gttatctttg
    41101 ccagttcgat tactgcagcg cctgcggcta ttcttcagtt tttgagtgcc acaggtcatg
    41161 attgggcttg ggtaagggta gcacaagaga tgttggcaac tacttctcca actggtattg
    41221 ccatgtatgc tttgttgatt attctcttta cattcttcta tacgtttgta cagattaatc
    41281 ctgaaaaagc agcagagagc ctacaaaaga gtggtgccta tatccatgga gttcgtcctg
    41341 gtaaaggtac agaagaatat atgtctaaac ttcttcgtcg tcttgcaact gttggttccc
    41401 tcttccttgg tgtgatttcc attttaccga ttgcagctaa agatgtattt ggtctttctg
    41461 atgttgttgc ctttggtgga acaagtctct tgatcattat ctctacaggt atcgaaggaa
    41521 tcaagcaatt ggaaggttac ctattgaaac gtaagtatgt tggtttcatg gacagaacag
    41581 aataaaagta tttactgaat cagtaaatgc tgagggagtg gaggtttaaa ctctgacatt
    41641 tgtaagagtt ggatctcccc tcttctattt tgtttttaaa taggggtgaa aagacttttt
    41701 gcttctattt aaaaataaaa taaggagatc aaatcatgaa tcttttgatt atgggcttac
    41761 ctggtgcagg taagggaact caagcagcaa aaatcgtaga acaattccat gttgcacata
    41821 tctcaacagg tgatatgttc cgcgctgcaa tggcaaatca aactgaaatg ggtgttcttg
    41881 ctaagtcata tattgacaag ggtgaattgg ttcctgacga agttacaaat ggaatcgtaa
    41941 aagaacgcct ttcacaagat gatattaaag aaacaggatt cttattggat ggttacccac
    42001 gtacaattga acaagctcat gccttggaca aaacattggc tgaacttggc attgaactag
    42061 aaggtgttat caatattgaa gtgaaccctg acagcctctt ggaacgtttg agtggccgta
    42121 tcatccaccg cgtaactgga gaaactttcc acaaggtctt taacccacca gttgactata
    42181 aagaagaaga ttactaccaa cgtgaagatg ataagcctga gacagtaaaa cgtcgtttgg
    42241 atgttaatat tgctcaagga gaaccaatca ttgctcacta ccgtgccaaa ggtttggttc
    42301 atgacatcga aggtaatcaa gatatcaatg atgtcttctc agatattgaa aaagtattga
    42361 caaatttgaa ataaagcgtt tttcatactt gcaaaaattc gctacaaatg ttatactgag
    42421 atagtctgac ttataattgt tgtctctgtg tctagaggca tcgaatcgaa atttatggag
    42481 gtgcttttgc gtggcaaaag acgatgtgat tgaagttgaa ggcaaagtag ttgatacaat
    42541 gccgaatgca atgtttacgg ttgaacttga aaatggacat cagattttag caacagtttc
    42601 tggtaaaatt cgtaaaaact atattcgtat tttagcggga gatcgtgtta ctgtcgaaat
    42661 gagtccatat gacttgacac gtggacgtat cacttaccgc tttaaataat cgaaaaactt
    42721 ggagggataa gaaatgaaag taagaccatc ggtcaaacca atttgcgaat actgtaaagt
    42781 tattcgtcgt aatggtcgtg ttatggtaat ttgcccagca aatccaaaac acaaacaacg
    42841 tcaaggataa gatagaaagg agaaaacatg gctcgtattg ctggagttga tattccaaat
    42901 gacaaacgcg tagtaatctc attgacttat gtttatggta tcggacttgc aacatctaag
    42961 aaaattttgg ctgctgctgg aatctcagaa gatgttcgtg tacgtgatct tacatcagat
    43021 caagaagatg ctatccgtcg tgaagtggat gcaatcaaag ttgaaggtga ccttcgtcgt
    43081 gaagtaaact tgaacatcaa acgtttgatg gaaatcggtt cataccgtgg tatccgtcac
    43141 cgtcgtggac ttcctgtccg tggacaaaac actaaaaaca acgctcgcac tcgtaaaggt
    43201 aaagctgttg cgattgctgg taagaaaaaa taatatagga ggtaaaagtc ttggctaaac
    43261 caacacgtaa acgtcgtgtg aaaaagaata tcgaatctgg tattgctcat attcacgcta
    43321 catttaataa cactattgtt atgattactg atgtgcatgg taatgcaatt gcttggtcat
    43381 cagctggtgc tcttggtttc aaaggttctc gtaaatctac accattcgct gctcaaatgg
    43441 cttctgaagc tgctgctaaa tctgcacaag aacacggtct taaatcagtt gaagttactg
    43501 taaaaggtcc aggttctggt cgtgagtcag ctattcgtgc gcttgctgcc gctggtcttg
    43561 aagtaacagc aattcgtgat gtgactccag tgccacacaa tggtgctcgt cctccaaaac
    43621 gtcgccgtgt ataatcatcg cattacactg cttttcgttt aagagggagt aactaaatga
    43681 tcgagtttga aaaaccaaat ataacaaaaa ttgatgaaaa taaagattat ggcaagtttg
    43741 taatcgaacc acttgaacgt ggctacggta caactcttgg taactctctt cgtcgtgtac
    43801 ttctagcttc tctaccagga gcagctgtga catctatcaa cattgatggt gtgttacatg
    43861 agtttgacac agttccaggt gttcgtgaag acgtgatgca aatcattctg aacattaaag
    43921 gaattgcagt gaaatcgtac gttgaagacg aaaaaatcat cgaactggat gttgaaggtc
    43981 ctgctgaagt aacagctggt gacattttga cagatagcga tattgaaatt gtaaatccag
    44041 atcattatct ctttacaatc ggtgaaggtt cttctctaaa agcgactatg actgttaaca
    44101 gtggtcgtgg atatgtacct gctgatgaaa ataaaaagga taatgcacca gttggaacac
    44161 ttgctgtaga ttctatttat acaccagtta caaaagtcaa ctatcaagtg gaacctgctc
    44221 gtgtaggtag caatgatggt ttcgacaaat taacccttga aatcttgaca aatggaacaa
    44281 ttattccaga agatgcttta gggctttcag cacgtatttt gacagaacat cttgatttgt
    44341 ttacaaatct tactgagatt gctaagtcaa ctgaagtgat gaaagaagct gatactgaat
    44401 ctgacgaccg tattttagat cgtacgattg aggaactgga cttgtctgtg cgttcataca
    44461 actgtttaaa acgtgccggt atcaatactg tgcatgattt gacagaaaaa tctgaagcag
    44521 agatgatgaa agtacgaaat cttggacgca agagtttgga agaagtgaaa ctcaaactca
    44581 ttgatttggg tcttggatta aaagataaat aaaggaggaa tacatggctt accgtaaact
    44641 aggacgcact agctcacaac gtaaagcaat gcttcgcgat ttgacaactg accttttgat
    44701 caacgaatca atcgtgacaa ctgaagctcg tgctaaagaa atccgtaaaa ctgttgaaaa
    44761 aatgattact ctaggtaaac gtggtgattt gcatgcacgt cgtcaagcag ctgctttcgt
    44821 acgtaatgaa atcgcatctg aaaactatga tgaagcaact gataagtaca cttctactac
    44881 agcacttcaa aaattgttct cagaaatcgc acctcgttat gctgaacgta acggtggata
    44941 cactcgtatc cttaaaactg aaccacgtcg tggtgatgca gcgccaatgg cgatcatcga
    45001 attagtataa aatcatcaat tttgttgagt gttatgatga tggagtcttg tgctcttagt
    45061 ctagctctgg tctaccgcta ggatttcggt cctagcggga acactcatca taagttggga
    45121 tagtagacgc ttgtttacga aattgttttt ttcttaagaa caacttcgta agcaggcgtt
    45181 tttgagtatt ttcgttagaa ttatgctata ctatttgaaa agaatcctgt ttaatgttaa
    45241 ggtttcttat tttaagaaga attggagttt acttatgaaa gccattataa ctgttgttgg
    45301 taaagataaa tctggaattg ttgcaggtgt ttctggtaaa attgcagaat taggattgaa
    45361 tattgacgat atctctcaaa ctgtattgga tgaatatttt acgatgatgg ctgttgtatc
    45421 tagtgatgaa aagcaagatt ttacctatct tcgtaatgaa tttgaagctt ttgggcaaac
    45481 tttgaatgta aaaatcaata ttcagagtgc agcgattttc gaagctatgt ataatatcta
    45541 ggaggtcatc atggatatta gacaagttac tgaaaccatc gccatgattg aggagcaaaa
    45601 cttcgatatt agaaccatta ccatggggat ttctcttttg gactgtatcg atccaaatat
    45661 caatcgtgct gcggagaaaa tctatcaaaa aattacgaca aaggcggcta atttagtagc
    45721 tgttggtgat gaaattgcgg ctgagttggg aattcctatc gttaataagc gtgtatcggt
    45781 gacacctatt tctctgattg gggcagcgac agatgcgacg gactacgtgg ttctggcaaa
    45841 agcgcttgat aaggctgcga aagagattgg tgtggacttt attggtggtt tttctgcctt
    45901 agtacaaaaa ggttatcaaa agggagatga gattctcatc aattccattc ctcgcgcttt
    45961 ggctgagacg gataaggtct gctcgtcagt caatatcggc tcaaccaagt ctggtattaa
    46021 tatgacggct gtggcagata tgggacgaat tatcaaggaa acagcaaatc tttcagatat
    46081 gggagtggcc aagttggttg tattcgctaa tgctgttgag gacaatccat ttatggcggg
    46141 tgcctttcat ggtgttgggg aagcagatgt tatcatcaat gtcggagttt ctggtcctgg
    46201 tgtggtgaaa cgtgctttgg aaaaagttcg tggacagagc tttgatgtag tagccgaaac
    46261 agttaagaaa actgccttta aaatcactcg tatcggtcaa ttggttggtc aaatggccag
    46321 tgagagactg ggtgtggagt ttggtattgt ggacttgagt ttggcaccaa cccctgcggt
    46381 tggagactct gtggcacgtg tccttgagga aatggggcta gaaacagttg gcacgcatgg
    46441 aacgacagct gccttggccc tcttgaacga ccaagttaaa aagggtggag tgatggcctg
    46501 taaccaggtc ggtggtctat ctggtgcctt tatccctgtt tctgaggatg aaggaatgat
    46561 tgctgcagtg caaaatggct ctcttaattt agaaaaacta gaagctatga cggctatctg
    46621 ttctgttgga ttggatatga ttgccatccc agaagatacg cctgctgaaa ctattgcggc
    46681 tatgattgcg gatgaagcag caatcggtgt tatcaacatg aaaacaacag ctgttcgtat
    46741 cattcccaaa ggaagagaag gcgatatgat tgagtttggt ggtctattag gaactgcacc
    46801 tgttatgaag gttaatgggg cttcgtctgt cgacttcatc tctcgcggtg gacaaatccc
    46861 agcaccaatt catagtttta aaaattaaga aaataggaga aattttaagt tctatttaag
    46921 attagacgtg tatactataa tcattaaata aagacctcct aatattattt gaaacagata
    46981 acactgaatt agtttgaatt tgattttcat ctaatatctt tatttaatga actcctaaac
    47041 tttttcataa taatctcctt caaaagtcgc ctgtatgggt ggcttttatt ttatcattca
    47101 tgatataata gaagcaaacg gaggacggaa aatggtaaaa gtacgattgt atttggtacg
    47161 tcatggcaag accatgttta acacgattgg tcgcgcgcaa ggttggagcg atactccctt
    47221 aactgctgaa ggtgaacgag ggattcaaga gttaggaatt ggtttgcgag aatctgatct
    47281 acagtttgag cgcgcttatt cgagtgattc tggtcgtacc attcagacca tgggaattat
    47341 ccttgaagaa cttggcttgc aggggaaaat cccttatcgc atggacaagc gtatcagaga
    47401 atggtgtttc ggtagttttg atggagccta tgatggcgat cttttcatgg gcattattcc
    47461 tcgtatcttt aatgtggacc acgttcacca attgtcttat gctgaactgg ctgagggctt
    47521 ggtagaggtc gatacagctg gttgggctga aggctgggaa aaactcagtg gccgaatcaa
    47581 ggaaggcttt gaaatgattg caaaagaaat ggaagatcaa ggtggaggta acgcccttgt
    47641 tgtcagccat ggaatgacta ttggaaccat tgtttatctg attaatggca tgcatccgca
    47701 tggtctagat aatggtagcg tgacgattct tgaatatgag gacggtcagt ttagggttga
    47761 agttgtcggt gaccgtagtt accgagagct aggacgtgag aagatggaag aaggctctat
    47821 ttaatcagtc tagacttgct tgccatgagc tagggatttg ataagaatat caagataaga
    47881 aaaaacagcc gagggtactc ctttcggctg tttttgatgt ggaaaactaa agtgtaatgc
    47941 tattgctttt agagattttc ataaacaaga gcaaggaacc tactgttaga acagtcagga
    48001 tagttgacaa ggctgcggct acaccgtaat ttcctctgag aacctctgta taaatagcta
    48061 cagtcattgt tcttgttttg acattgtaga ggaggataga agtagagagt tttgaaatca
    48121 ttatgaccta agataagatg gctccagaaa tgataccaga tagcatcatt ggagttgtaa
    48181 tcttagcaaa ggtattgaga cgactacttc ctaagctttc agcagcttct tcaatacttg
    48241 gtgctatttg ttgtaagcta gcaacagatg agcgaatagt ataaggtaat cttctgacag
    48301 atagagacat aatcaagatg aaagcagtcc ctgtaatcat aagaaatcca cttccaaata
    48361 gaccagtatt gaaggaagaa atgaaggcaa tccctagaac ggttcctggt acaatataag
    48421 gtaccatact gaggctgtca attaagtttg taaacaaatt ccgttttcta acggctaggt
    48481 aggagataaa tgtcgcaaat agaacaacta gaactaaggc aatcaaaggg atacgaatgg
    48541 tattgaaaat agcagatccc atacgattga aagctacctt gtaactgttt ggagaataac
    48601 ctttaacaga taccatacct gatgttttta ggaaagaggt ataaattaag tagatttgag
    48661 gtaaaacaga gataaagata attccgtaga ctgttgcata aatggcagct atttttcctt
    48721 ttgtagtttt tttaggctca attggatgga gcagattcat gctgaaactg tagcggtttg
    48781 caatgtgttt ttggataagg aaaattgcca agacaatgat aatcgccata attgcaaaag
    48841 cagaatttcc tccaacctcg ctaataaatt gggtataaat caggacaggg aaggtccgat
    48901 atccttcgcc aatcaacata ggcgttccaa agtctgagaa tgctctcata aatacaagca
    48961 aggagctgct agtaaggttg gaactaggag aggtaaaaca accgttacga taggtttaaa
    49021 tccgaaggac cccatgcttt cagctgcttc aagtagagaa ttgtcaatac tgttcattgt
    49081 tccagcaaca tatagaaata ccagtgggaa tagttgcagt gtaaagacaa gtacaattcc
    49141 tttgaatcca taaatatcga tagctggaag atgaagggca tttgtcaaaa atttagtgat
    49201 gaccccattt cgtcctagca agagaaccca ggagtaggct cctacgaaag gagctgacat
    49261 ggaagcaatg ataatcaata tttgtagaaa tttcttcccc ttgaagtcat acatagagaa
    49321 gagataagct aatagggttc ctacaactaa ggaagtgaca gtagcggtaa tggaaacctt
    49381 gaaactgttg actagtgtct cagagtagta gactttacta aagaaagtga caaaattagc
    49441 tagtgagaat tgtccttcat gtataagtgc ttgcttgagc acggtaacga taggataaac
    49501 gagaaagaca agataggtaa gaaagatgaa gaaagaggag gttgtccaaa tatttagttt
    49561 tttacattcc atggttgact ccttttatca ggttttggga accatctgca gaaaagatgt
    49621 ttaatttttg cgtattgatt cgtagacgaa tacgattgcc tttttgtagt tcttcttcaa
    49681 aagttgattc ttcactaact tgaatttttg aggcaaaacc tgtctcaatg aaatactccg
    49741 tatttagtcc aagatagacg ctatcgctaa tagttccttc aatatctcca gattcatctt
    49801 tgataaactc ttcgggacga atgcttacat gaatagcttg ctcctcaacc tgatcaagag
    49861 ctggcattcg aagggcatag ccatctgaaa agacgatata agcgccgtcg ctccgttttt
    49921 caagattagt agggataata tttgtgcgtc cgataaaggt tgccacaaac tcattagctg
    49981 gtttatgata gagttctttt ggtcggccga tttgttggat caccccatct ttcataacag
    50041 caatttggtc tgaaatagcc atggcttctt cttggtcgtg ggttacataa acagttgtaa
    50101 ttcccacttc gtgttggatt tctcggatgg cttgacgcat atccaagcga agtttggcct
    50161 ccagattact aagtggctcg tccatgagga gaacacttgg attaaccgct aaggcgcatg
    50221 ccaaggtgac acgttgttgt tgtccaccac tgagtttatc gggctttcaa tccgcatatt
    50281 gagcaatttg catgagttca agatacttgt tggtctgttg aatcaattct tcttttggaa
    50341 ccttcttttg cataagacca aaagcaacgt tgtctcggac agtcaaatgt gggaaaatag
    50401 cgtagttttg gaaaaccagc ccgatattgc gtttgctggg ttccatatta ttgatttttg
    50461 tatcatcgaa gtaaaattct ccatctttga tactgttgaa acctgcaatc atacgaagaa
    50521 gggtcgtttt cccacatcct gaagctccaa gaagggtaaa gagacttcct tttggaattg
    50581 taatgttcaa attctcaata acagggacat cgtggtagat ttttttggcg ttaataattt
    50641 cgatctcact catagtgaac ctcttttact gtttagattg gatatctgta aagacttcgt
    50701 tgtatttctt aacgatatct gatttattct tgatgacata atcataatct tcagtgagtg
    50761 ttttgatttt gtcaattggt ttcatgtttt cgcttgtttt agcattttta cgaacaggac
    50821 ggttagtagt ggttgtacca agtgtatctt gtacttcttg agagataata aaatcgataa
    50881 atttcttggc attttccata tttttagctt ttttaacgat agcagcacta gcaggtagga
    50941 agacggttcc ttcttttgga tagactactt taatgttagc tccgtcattt aagagtttaa
    51001 ctgctggatc ctcataagag agaccaacag ccatttctcc atcaacgact gctttataga
    51061 caccagatga acttgaaccg attttatagt gtattgaaac tagaatagta cacctctact
    51121 tctaaaacat tgttagaaat cgatttgact gtcctgatta atttgtcctg ttcttatttc
    51181 attttactat accatcaata agtgtgaaaa gatcttttac ataagaccaa gccttatcat
    51241 ctttgtaacc accttgagct tgtagcatat ttgttaattg agcaaaggcg ctagaagagt
    51301 ttgctgggtc agcagttgcg atttttcctt ttagttcagg tttgagaagg tcgctatatc
    51361 cttcgatgtt catgccttta gttaaatcag ggtggacgat taaaacacta ccatctagtg
    51421 tataaggagt agagaagcca gttgtgtttt gatattcttt gataacatta tcattttctt
    51481 ttgaaatata gttttcaaag agttctccgt gggtagcata ttgtgtataa gaaccaccaa
    51541 agataacatc agctacagga acttcttttt ctgactctag ttttttgaaa agttctccag
    51601 taccagcttg aatcagttct attttgatac catatttttc ttcaaaggca ggaatagttg
    51661 ctccaattaa gccttctgag tttggtgaat aaacgactag cgaaccaccg tctcctttat
    51721 cagatgaact gtcatcggca gattcattag aagaacaagc agcataatac atccatttct
    51781 ttttcatgat ggatatctcc gttgtgttat ttaagtttat tttaaaacaa tgtaagcgtt
    51841 tttaaaacct acaattctat tctatagtgt attgaatcta taacagtaca ctttgactgc
    51901 taaaatattt ctataaatta atttgacttt cctgatagag atgttcacat cttatttcaa
    51961 ttcactatat tagagtaaaa ttctctacaa aaagaagaat agcctatttg actattcttc
    52021 cgagtgattt caatttcttt ggggaaatat ggagatactt tttaaatact ttggcaaaat
    52081 atttatagtc tgaaaatcca acttggtcag agatagcgct taaaggggag ttgggagatt
    52141 cagccatctt atctatagct tgtttcaggc gatattgtaa gatatattca tttagagtca
    52201 tggggaagtc ttctttgata accttatata gatgcttgtt atctgcaaat agctagagca
    52261 tttcaaggaa ataaactaga aataacaatt aatatggtgg ttcagaaata ccttttgata
    52321 atcaataaga tcttcaggat gaagtgcgtt gattccatcc atttcatatt tccgatttaa
    52381 taaacgatat ttgttttcac caaattgatg aaaagggagt agttgaactt ggtcgatatt
    52441 taatgagtta aatagagtag cgaatttttc tgcatcctct aaactattgt taaaattagg
    52501 aataactggg attcttaaaa cgatagtttt attttgagaa aaagcataat gaatgttttt
    52561 aataatcatt tgattaaaaa ccccagtcac ttttttatgt tttatagaat tataatgttt
    52621 taggtctgtg tagataaaat ccacatattg aattaaatca ataaattttt catgatcaac
    52681 aaaggcagta gtttcaatgg cagtgtgtat gtgatgttct ttagctgatt ttaagatggc
    52741 tttagcaaat tcaaactgag caaatatttc acctcctgat aaagttaaac ctccaccgga
    52801 ttcttcgtaa aattctttgt cttttaatac ctctgtaata atttcttcta cagtcttttc
    52861 ttcaccgact aaggtgaatt tctctcgttg agcatctttc attttttcag gtttcattct
    52921 ttgagattca ggattagaac accatggaca gcgcagagga catcctttta aaaaaacagt
    52981 tgtacgaata cccgggccgt catgaattga aaagtgttga atattaaaaa taattccttt
    53041 agatatttcc ataagagttc ctcctcttca taagtctatc ctatcacaaa aacgaaagaa
    53101 aaacaattac gaacgaaagc ttaatttgtt gttttttgct ttttattttg gtagaataaa
    53161 acggaggtgt aaaatgaaaa gattggaaca aattattaaa ttagtatcag aatatgaaaa
    53221 gatcgacgtt aatacattat cggaaaaatt aaatgtatcg aaagtaacga ttagaaaaga
    53281 tttagataaa ttagagtcaa aaggtttatt acacagagag catggatatg ctgtattaaa
    53341 tagtggagat gacttaaatg tacgtttgtc aattaactat gaaattaaga gaaaaattgt
    53401 tcaggaagca gtaaaattgg tgtcagataa tgaaacaata atgatagaat ctggatcgac
    53461 ctgtgcttta cttgctgagg aaatttgcaa gcaaaaaaga aatgttacga ttgtaacaaa
    53521 ttcatttttt atagcaaatt ttgtgagagc ttatgattca tgtcgtatta ttgttcttgg
    53581 tggagagttt cagaaggatt cacaggttac tgtgggacct ttattaaaag aaatgataca
    53641 gacttttcat gtgcatcaag cttttgttgg gacagatggt tacgataaag agatgggctt
    53701 tacaggaaaa gatttaatgc gcagtgaggt agttcaatat atttcagcag cgtcggataa
    53761 agtcattgta ctaactgact caagtaaatt tgataaaagg ggtacagtaa gaagatttgc
    53821 tttaagtcaa gtctatgaag taataacaga cgaaaaactt tctaaacaaa atatagctac
    53881 attagaaaat gctgggataa tggttaaggt agtttcgtaa gaggttaaat gtatgaatca
    53941 agataggaat aaactgctct ctaaaattgc ttatctgtat tatattgaaa acttaaatca
    54001 gtcacaaata gcagcaaaat taggaattta tagaacctct attagtagaa tgttaacaga
    54061 agcaaggaat gcaggaattg ttaaaattga aatagagaat tttgatacca atatgtttaa
    54121 gttggaaaat tatgtaaaag aaaaatatgg tctggaaagt ttagaaatta ttccaaatga
    54181 atttgatgat aatccaacaa ttttatctga aagaatttct caagttgcag caggtgtcct
    54241 taggaatcta attgatgata atatgaaaat tggcttttct tgggggaaaa gtttaagtaa
    54301 tttagtagat ttaattcaca gtaaaagtgt ccgaaatgtt cacttctatc ctctagcagg
    54361 tggtcctagt cacatacacg ctaaatacca tgtgaataca ctgatttatg aaatgtctag
    54421 aaaatttcat ggagagtgta catttatgaa tgcaacgatt gtgcaagaaa ataaattgtt
    54481 agcagatggt attttgcaat caagatattt tgaaaatttg aaaaatagtt ggaaagattt
    54541 agatatagct gtagtcggaa ttggtgattt tagcaataaa gggaaacatc aatggttaga
    54601 catgcttaca gaggatgact ttaaagaatt gaccaaagtt aaaactgtag gagaaatttg
    54661 ttgtcgattt tttgattcaa aaggtaaaga agtctatgaa aacttacagg aaagaacgat
    54721 agccatctct ttggaagatt taaaaaatat tcctcaaagt ttagctgttg cttacggtga
    54781 tacgaaagta tcttcgattc tttctgtctt gcgtgctaat ttagtaaatc atttgattac
    54841 agataaaaat acaattttaa aagttttgga agaagatggt gatttgactt ttagagagat
    54901 tctaggtgag tgaaaatgat agactgatca gtttatcgtt ttttcttttt agtcgattgc
    54961 acatttgtgc ttatataaac aaaaatagtt tatctgttgt tttt
//
LOCUS       DAVKEV010000005        53479 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVKEV010000005 DAVKEV010000000
VERSION     DAVKEV010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53479
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.005"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            49..369
                     /locus_tag="VWZ68_000316"
     CDS             49..369
                     /locus_tag="VWZ68_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9371408.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            415..723
                     /locus_tag="VWZ68_000317"
     CDS             415..723
                     /locus_tag="VWZ68_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9371409.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            740..2038
                     /locus_tag="VWZ68_000318"
     CDS             740..2038
                     /locus_tag="VWZ68_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9371410.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLAMSTMVYFPFFKIQDRLACQNEIKQS"
     gene            2189..4627
                     /locus_tag="VWZ68_000319"
     CDS             2189..4627
                     /locus_tag="VWZ68_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEU9371411.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            4646..5314
                     /locus_tag="VWZ68_000320"
     CDS             4646..5314
                     /locus_tag="VWZ68_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEU9371412.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            5332..6420
                     /locus_tag="VWZ68_000321"
     CDS             5332..6420
                     /locus_tag="VWZ68_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEU9371413.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            6902..9403
                     /locus_tag="VWZ68_000322"
     CDS             6902..9403
                     /locus_tag="VWZ68_000322"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEU9371414.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            9597..10292
                     /locus_tag="VWZ68_000323"
     CDS             9597..10292
                     /locus_tag="VWZ68_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9371415.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            10304..10720
                     /locus_tag="VWZ68_000324"
     CDS             10304..10720
                     /locus_tag="VWZ68_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9371416.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(11535..11627)
                     /locus_tag="VWZ68_000325"
     CDS             complement(11535..11627)
                     /locus_tag="VWZ68_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU9371417.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            11788..12759
                     /gene="ruvB"
                     /locus_tag="VWZ68_000326"
     CDS             11788..12759
                     /gene="ruvB"
                     /locus_tag="VWZ68_000326"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEU9371418.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            12740..13312
                     /locus_tag="VWZ68_000327"
     CDS             12740..13312
                     /locus_tag="VWZ68_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEU9371419.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            13543..14301
                     /locus_tag="VWZ68_000328"
     CDS             13543..14301
                     /locus_tag="VWZ68_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEU9371420.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            14310..15113
                     /locus_tag="VWZ68_000329"
     CDS             14310..15113
                     /locus_tag="VWZ68_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEU9371421.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            15135..16394
                     /gene="rseP"
                     /locus_tag="VWZ68_000330"
     CDS             15135..16394
                     /gene="rseP"
                     /locus_tag="VWZ68_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEU9371422.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPKDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            16407..18260
                     /locus_tag="VWZ68_000331"
     CDS             16407..18260
                     /locus_tag="VWZ68_000331"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEU9371423.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTSEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            18359..19738
                     /gene="bglA"
                     /locus_tag="VWZ68_000332"
     CDS             18359..19738
                     /gene="bglA"
                     /locus_tag="VWZ68_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU9371424.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEHYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            19931..21739
                     /gene="glmS"
                     /locus_tag="VWZ68_000333"
     CDS             19931..21739
                     /gene="glmS"
                     /locus_tag="VWZ68_000333"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEU9371425.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVIDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLSLLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGFDVDKPRNLAKSVTVE"
     gene            complement(21877..21954)
                     /locus_tag="VWZ68_000334"
                     /pseudo
     CDS             complement(21877..21954)
                     /locus_tag="VWZ68_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            22011..23060
                     /locus_tag="VWZ68_000335"
     CDS             22011..23060
                     /locus_tag="VWZ68_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEU9371426.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLALLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(23160..26996)
                     /gene="spuA"
                     /locus_tag="VWZ68_000336"
     CDS             complement(23160..26996)
                     /gene="spuA"
                     /locus_tag="VWZ68_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEU9371427.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNKSDISSLGNANASLEKTEEKPATEPT
                     TPAASPADPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQ
                     GLWTWDDVEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNL
                     TGDKSVEKLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVK
                     NPSSAQWPDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFT
                     DLKNHSQIFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKH
                     SNITNHLGNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDE
                     TYSYDGKLGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTW
                     KQTLDSTNKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSNDAKIDDAHKVA
                     KAAFVDPAKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEA
                     FIEKLDYLKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSL
                     TGMYSSDPKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFM
                     DADGTPRTSFGGGRLGTTHHMTKRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEA
                     YKAARALNPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGY
                     PNEGQPAFITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSI
                     KKDPSKAENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDK
                     VPNKSHLLRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKG
                     LIALRQSTDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVN
                     ADEKAREFNLGTAFAHLRNAEVLADENQAGPVGIANPKGLEWTEKGLKLNALTATVLR
                     VSQNGTSHESTAEEKPDSTPSKPEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQ
                     AEQPAQEAQASSVKEAVQNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGISL
                     LALLGLGFLLKNKKEN"
     gene            27413..27826
                     /gene="rpsL"
                     /locus_tag="VWZ68_000337"
     CDS             27413..27826
                     /gene="rpsL"
                     /locus_tag="VWZ68_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEU9371428.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            27846..28316
                     /gene="rpsG"
                     /locus_tag="VWZ68_000338"
     CDS             27846..28316
                     /gene="rpsG"
                     /locus_tag="VWZ68_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEU9371429.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            28741..30822
                     /gene="fusA"
                     /locus_tag="VWZ68_000339"
     CDS             28741..30822
                     /gene="fusA"
                     /locus_tag="VWZ68_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEU9371430.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            30926..35317
                     /locus_tag="VWZ68_000340"
     CDS             30926..35317
                     /locus_tag="VWZ68_000340"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEU9371431.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREVFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            35419..35682
                     /locus_tag="VWZ68_000341"
     CDS             35419..35682
                     /locus_tag="VWZ68_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEU9371432.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            35675..35953
                     /locus_tag="VWZ68_000342"
     CDS             35675..35953
                     /locus_tag="VWZ68_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEU9371433.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            35974..36126
                     /locus_tag="VWZ68_000343"
     CDS             35974..36126
                     /locus_tag="VWZ68_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371434.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            36148..37389
                     /locus_tag="VWZ68_000344"
     CDS             36148..37389
                     /locus_tag="VWZ68_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEU9371435.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            37399..37629
                     /locus_tag="VWZ68_000345"
     CDS             37399..37629
                     /locus_tag="VWZ68_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU9371436.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            37852..38574
                     /locus_tag="VWZ68_000346"
     CDS             37852..38574
                     /locus_tag="VWZ68_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU9371437.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            38791..40125
                     /gene="pepC"
                     /locus_tag="VWZ68_000347"
     CDS             38791..40125
                     /gene="pepC"
                     /locus_tag="VWZ68_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEU9371438.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQTKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(40181..41092)
                     /locus_tag="VWZ68_000348"
     CDS             complement(40181..41092)
                     /locus_tag="VWZ68_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9371439.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(41116..41919)
                     /locus_tag="VWZ68_000349"
     CDS             complement(41116..41919)
                     /locus_tag="VWZ68_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEU9371440.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(41947..42936)
                     /gene="manX"
                     /locus_tag="VWZ68_000350"
     CDS             complement(41947..42936)
                     /gene="manX"
                     /locus_tag="VWZ68_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEU9371441.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(43169..44188)
                     /gene="adhP"
                     /locus_tag="VWZ68_000351"
     CDS             complement(43169..44188)
                     /gene="adhP"
                     /locus_tag="VWZ68_000351"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEU9371442.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSETMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(44527..45339)
                     /locus_tag="VWZ68_000352"
     CDS             complement(44527..45339)
                     /locus_tag="VWZ68_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9371443.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            45529..46947
                     /locus_tag="VWZ68_000353"
     CDS             45529..46947
                     /locus_tag="VWZ68_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEU9371444.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTKVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            47000..47707
                     /locus_tag="VWZ68_000354"
     CDS             47000..47707
                     /locus_tag="VWZ68_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9371445.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLMVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            47832..48776
                     /gene="folP"
                     /locus_tag="VWZ68_000355"
     CDS             47832..48776
                     /gene="folP"
                     /locus_tag="VWZ68_000355"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEU9371446.1"
                     /translation="MSSKANHAKTAICGIINVTPDSFSDGGQFFALEQALQQARKLIA
                     EGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDTWKSQVAEAAL
                     AAGADLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLIFPHFGFGQTF
                     TEKELADFETLPIEELMEAFFERALARAAEAGIAPENILLDPGIGFGLTKKENLLLLR
                     DLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTASAHVTSIAARQ
                     GVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            48778..50100
                     /locus_tag="VWZ68_000356"
     CDS             48778..50100
                     /locus_tag="VWZ68_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU9371447.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLESIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEEKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGCFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADH
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKARNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            50081..50635
                     /gene="folE"
                     /locus_tag="VWZ68_000357"
     CDS             50081..50635
                     /gene="folE"
                     /locus_tag="VWZ68_000357"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEU9371448.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            50678..51490
                     /gene="folK"
                     /locus_tag="VWZ68_000358"
     CDS             50678..51490
                     /gene="folK"
                     /locus_tag="VWZ68_000358"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEU9371449.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(51641..51958)
                     /locus_tag="VWZ68_000359"
     CDS             complement(51641..51958)
                     /locus_tag="VWZ68_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEU9371450.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            52315..52761
                     /gene="rplM"
                     /locus_tag="VWZ68_000360"
     CDS             52315..52761
                     /gene="rplM"
                     /locus_tag="VWZ68_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEU9371451.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISELI"
     gene            52780..53172
                     /gene="rpsI"
                     /locus_tag="VWZ68_000361"
     CDS             52780..53172
                     /gene="rpsI"
                     /locus_tag="VWZ68_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEU9371452.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
BASE COUNT        15508 a        10012 c        12216 g        15743 t
ORIGIN      
        1 aatttcaaat gaaaaaagct ttttacatag tgaaatgagg aggaatttat ggaaattatt
       61 gttccagatc aaattatcat gggtttaatt ttatatgctg gcgatgcgaa acaacatatt
      121 tataaagcat tagattacat aaaaaatggt acatgtgaac ggtgtgaaga agaaatccag
      181 ttagctgatg ccgccttatt agaagcccat aatctacaaa caaaattctt ggcacaagaa
      241 gcgtctggta caaagacaga aattacagct ctctttgttc attcacaaga tcatctcatg
      301 actagcatga cggagattaa tttaatcaaa gaaattatta gtttgagaaa agaacttcat
      361 aaaaaataat actagagtat tatcattgtt attaacatag aggaggaaaa cataatggtg
      421 aagattggtt tgttttgtgc agcaggtttt tctactggta tgcttgtaaa taatatgaaa
      481 attgcagcgc aatctagtgg agttgaggca gaaatagagg cgttttctca gtctaaatta
      541 gcggattatg cgccaaatat agatgttgca ctattgggtc cacaagttgc ttatacatta
      601 gataaatcaa aagaaatttg tgataagtgt gatgttccga tagctgttat tccgatgatg
      661 gactatggta tgttagatgg gaaaaaagta ttagatttgg ccctatcttt gattagtggg
      721 taagaaaagg agatttatta tgtcaaagat ggatgttcag aaaatcattg caccgatgat
      781 gaagtttgtg aatatgcgtg gcattatagc tctaaaagat gggatgttag caattttgcc
      841 attgacagta gttggcagtt tgttcttgat tatgggacaa ttgccgttcg aaggattaaa
      901 taagagcatt gctagtgttt ttggagctaa ttggacagag ccgtttatgc aagtatattc
      961 aggaactttt gctattatgg gtctaatttc ttgtttttca attgcctatt cttatgctaa
     1021 gaatagcgga gtagaggctt taccagctgg agttctatct gtatctgcat tctttatttt
     1081 gctaagatca tcttatatcc ctaaacaagg tgaggcgatt ggggacgcta ttagtaaagt
     1141 ttggtttgga ggccaaggaa ttatcggtgc tatcattata ggtttggtag taggaagtat
     1201 ttataccttc tttataaaga gaaaaattgt tattaagatg ccagaacaag ttccacaagc
     1261 tattgccaaa cagtttgaag caatgattcc agcatttgta attttcttat cttctatgat
     1321 tgtatatatt ttagcgaagt cattgactaa tggcggaaca ttcatagaaa tgatttattc
     1381 tgctattcaa gttccgttgc aaggtttaac tggatctttg tatggtgcta ttggaattgc
     1441 attctttata tcatttttgt ggtggtttgg tgttcatggg caatcggtag taaatggagt
     1501 agtgacagct ctgcttttat ctaatcttga tgctaataaa gctatgttag cctctggtaa
     1561 tctatcatta gaaaatggtg cacatattgt tactcaacaa tttttagatt catttttaat
     1621 tctatcaggt tcagggatta cgtttggtct tgtagttgcc atgctttttg cagcaaaatc
     1681 aaaacaatac caagccttag gaaaagttgc agcttttcca gcaatattta acgtaaatga
     1741 gccagttgta tttggatttc cgattgtcat gaatccagtt atgtttgtac ctttcattct
     1801 tgttcctgta cttgcagctg tgatagtata tggagctatt gcaacaggtt tcatgcaacc
     1861 attctcaggg gtaacattgc cttggagtac accagctatt ctatcaggat ttttggtggg
     1921 tggatggcaa ggtgttgtga ctcagttatt agtattggcg atgtctacaa tggtttactt
     1981 tccattcttt aagatacaag atcgtttagc ttgccaaaat gaaatcaaac aatcttagag
     2041 gtatttgtgt gttactgtta aactcacaca tttgtgctaa aaattagaga gttaaaattt
     2101 ttctagttaa aagcttgaaa atttctataa aaatcggtat tatattttcg aaagaaataa
     2161 aaatattttc gaaagaaagg tgcttacgat ggtaaataca gaagtagcaa gaacaacaat
     2221 caagacagaa tattttggca gccttactga aaggatgaac aaatatcgag aagatgtttt
     2281 aaataaaaaa ccttatattg atgctgagag agcagttcta gcaacacgcg cctatgaacg
     2341 atacaaggaa caacctaatg tcctaaaacg tgcatatatg ctgaaagaaa ttttggaaaa
     2401 tatgtctatc tatattgaag aagaatctat gattgcggga aatcaagctt cttccaataa
     2461 agatgctcct atttttccgg aatatacgct agaatttgtt ctcaatgagt tggatctttt
     2521 tgaaaagcgt gatggagatg ttttctatat tacagaagaa acaaaagaac aacttagaag
     2581 tattgctccg ttttgggaaa ataataattt acgtgctaga gctggtgcct tattacctga
     2641 agaagtgtct gtttatatgg aaacaggatt cttcggtatg gaaggtaaga tgaattctgg
     2701 agatgctcac ttagcagtta actatcagaa acttttgcaa tttggtttaa gaggttttga
     2761 agagcgggct cgtaaagcga aggtagctct agatttaaca gatccagcaa gtattgataa
     2821 atatcatttt tacgactcta tatttatcgt aatcgatgct attaaagtat atgcaaagcg
     2881 ctttgttgct cttgctaaaa gtttagccga aaatgcaaat cctaaacgta agaaagaatt
     2941 acttgagatt gcagatattt gctctagagt cccatatgaa ccggcaacta cttttgcaga
     3001 agctattcaa tcagtttggt ttattcaatg tattttacaa attgaatcta atggccactc
     3061 tctttcatat ggccgttttg atcaatatat gtatccatat atgaaggctg atttagaaag
     3121 tggtaaagaa acagaagata gcattgttga acgtctgaca aatctttgga ttaagacaat
     3181 tacaattaat aaggttcgca gtcaatcaca tacattttct tcagcaggaa gtcctttata
     3241 tcaaaatgtt acaattggtg gacagactcg agataagaag gatgctgtta acccattatc
     3301 ttatttggta ttaaaatcag ttgcacaaac ccatctaccg caacctaatc taactgtacg
     3361 ttaccatgca ggtttagatg ctcgtttcat gaatgagtgt attgaagtga tgaaacttgg
     3421 ttttggtatg cctgcattta ataatgatga gattattatt ccttctttta ttgcaaaagg
     3481 agtattggaa gatgatgctt atgattacag tgccattgga tgtgttgaaa cggcagttcc
     3541 agggaaatgg ggctatcgtt gcacaggtat gagttatatg aacttcccta aggttctact
     3601 tatcacgatg aatgatggaa ttgatccggc ttcgggtaaa cggtttgcac caagctttgg
     3661 tcattttaag gatatgaaga acttttctga attagaaaat gcttgggata aaacactaag
     3721 atatttgaca cgaatgagtg ttattgttga aaattctatt gatttatcat tggaacgaga
     3781 agttcctgat attctatgtt cagcattgac tgatgattgt attggtcgtg gaaaacacct
     3841 taaagaaggt ggagcagtat atgattatat atcaggattg caagttggaa ttgcaaattt
     3901 gtcggattca ttagctgcaa ttaaaaaatt ggtgtttgag gaagaacgta taagcccaag
     3961 tcagctttgg catgcactgg aaacagatta tgccggagaa gaaggtaagg tcattcaaga
     4021 aatgttgatt catgatgcac ctaagtatgg taatgatgat gattatgctg acaaattggt
     4081 tactgctgct tatgacattt atgttgatga aattgctaaa tatcctaata cacgttatgg
     4141 aagaggtcca attggaggaa ttcgttattc aggaacatct tctatctcag ccaacgtagg
     4201 gcagggacgt ggaacattag caactccaga tggacgcaac gcgggtacac cgttagcaga
     4261 gggttgttca ccatcacata atatggatca acacggccct acatctgttt taaaatctgt
     4321 ttcaaaatta ccaacagatg aaatcgtagg tggggttctc ttaaatcaga aagtaaatcc
     4381 tcaaacgtta gccaaagaag aagataaatt aaaactaatt gctttgttac gaacattctt
     4441 taatcgttta catgggtacc atattcaata caatgttgtt tccagagaga cgctgattga
     4501 cgctcagaaa catcctgaaa aacacagaga cttaattgtt cgtgttgcag gatactctgc
     4561 attcttcaat gttctttcta aggcaaccca agatgacatt ataggacgta ctgagcatac
     4621 tttgtaaaat aaagaggttc tttttatgga atttatgctt gacacattaa atttagatga
     4681 gattaaaaag tggtctgaaa ttttgccgct agctggggta acttcaaatc ccactattgc
     4741 aaaaagagag ggttctatta atttttttga acgaatcaaa gatgtaagag aattgattgg
     4801 ctctacaccc tctattcatg ttcaggtgat ttctcaagat tttgaaggca tcttaaagga
     4861 tgctcataaa attcgaagac aagcaggaga tgatatattt atcaaagtac ctgttactcc
     4921 agctggatta cgtgcaataa aggcgctaaa aaaagagggc taccatatca ctgcaacagc
     4981 tatttataca gttattcagg gattattagc tatcgaagca ggagcggatt acctagctcc
     5041 atattataat agaatggaaa atctgaacat tgattcaaat tctgtcattc gtcaattagc
     5101 tcttgctatt gatagacaga actctcctag taagatttta gctgcatcct ttaaaaatgt
     5161 agcacaagta aataatgctt tagctgcagg tgcgcatgct gttacagcag gagcggatgt
     5221 ttttgaatca gctttcgcca tgccatctat ccaaaaggcg gttgatgatt tttctgacga
     5281 ttggtttgtt attcaaaata gtcgttccat ttagatagag aggaaataca tatgagaatt
     5341 tttgctagtc cttctagata tattcagggg gaaaatgcct tgtttgaaaa tgccaaatca
     5401 attttggatt tgggaaattg ccctattcta ttatgcgatc agttggttta tgatattgtt
     5461 ggaaaacgat ttgaagatta cctacatagg tatggtttcc atattgttct ggcgctattt
     5521 aatggtgaag cttctgacaa tgaaatcaat cgagttgttg ccttggctga gaaagaaaat
     5581 tgtgatagta ttatcggtct tggtggggga aagacgattg atagcgcaaa agctattgca
     5641 gatttgattg aaaagcctgt tattattgct ccaacaattg catcgaccga cgcacctgta
     5701 tctgctttat ctgttattta tacagatgaa ggtgcatttg atcattatct attttattct
     5761 aaaaatccag atttagtttt ggttgataca aaagttattt cacaagcccc taagcgttta
     5821 ttagcgtctg gtattgcaga tggtttagca acttgggttg aggcgcgtgc ggttatgcag
     5881 gcaaatggaa aaactatgtt gggacaacag caaacattgg ctggagttgc aattgcgaag
     5941 aaatgtgaag aaacgctgtt tgcagatggt ttacaggcta tggcagcttg tgaagctaaa
     6001 gtggtgacac cagcattaga aaatattgtt gaagctaata ctttattgag tggtctaggt
     6061 tttgaaagtg gaggattagc tgcggcgcat gcaattcata atggttttac tgcattgaca
     6121 ggtgacattc atcatttaac acatggtgaa aaagtagctt atggaacttt agtacaacta
     6181 ttattggaaa atagacctaa agaagaactt gataagtata ttgagtttta caaaaaaatt
     6241 ggtatgccaa caactctaaa agaaatgcat ttggatcaag ttggatatga tgatttaata
     6301 aaagttggta aacaagcaac tatggagggt gagacaattc atcagatgcc gtttaagatt
     6361 tcgccttcag atgttgctca agctattatc gctgtagatg cctatgtaaa ttcaaaataa
     6421 acaataagga ctactgtttt ccaaatggta gtcttttatt gatccctgta ttgaattcta
     6481 tagaagattg aaataggatg agaacaaatc gattgggaaa gtaaaattaa tttctataaa
     6541 tgttttagca attgtttcgt actatttcag attcagtcta ctatatgttc ttcataaatc
     6601 aaaaagcgac ataggttgtc ggcaatcaaa aagcgacata ggttgtcggc tatttattgt
     6661 gaatacatta attagcattc cagttttatc ttcggtctaa aataagtatt ttgtgctata
     6721 cgagataagc ttcttgactt actccttgat ttactgcata acaatgggat aaaaagtggg
     6781 agatagagca attcatagtc atcaaaatta atgagataca gtatacagtt tttcctttaa
     6841 acacatttca aattccctca aaaatggtat aatagtaaca tcacaaaatt ggagagagac
     6901 catgagtttt tacaatcata aagaaattga gcctaagtgg cagggctact gggcagaaca
     6961 tcatacattt aagacaggaa cagatgcatc aaaacctaag ttttatgcgc ttgatatgtt
     7021 cccttatccg tctggagctg gtctgcacgt aggacaccca gaaggttata ctgcaaccga
     7081 tatcctcagt cgttacaaac gtgcgcaagg ctacaatgtc cttcacccaa tgggttggga
     7141 tgcttttggt ttgcctgcag agcaatacgc tatggatact ggtaatgacc cagcagaatt
     7201 tacagcggaa aacattgcca acttcaaacg tcaaattaat gcgcttggat tttcttatga
     7261 ctgggatcgt gaagtcaaca caacagatcc aaactactac aagtggactc aatggatttt
     7321 caccaagctt tacgaaaaag gcttggccta tgaagctgaa gtgccagtaa actgggttga
     7381 ggaattggga actgccattg ccaatgaaga agtgcttcct gacggaactt ctgagcgtgg
     7441 aggctatcca gttgtccgca aaccaatgcg ccaatggatg ctcaaaatca cggcttacgc
     7501 agagcgcttg ctcaatgact tagatgaact agattggtca gagtctatca aggatatgca
     7561 acgcaactgg attggtaaat caactggtgc caatgtaact ttcaaagtaa aaggaacaga
     7621 caaggaattt acagtcttta ctactcgtcc ggacacactt ttcggtgcga ctttcactgt
     7681 cttggctcct gaacatgaat tagtagacgc tatcacaagt tcagagcaag cagaagctgt
     7741 agcagactat aaacaccaag ccagccttaa gtctgacttg gctcgtacag accttgctaa
     7801 agaaaaaaca ggggtttgga ctggtgctta tgccatcaac cctgtcaatg gtaaggaaat
     7861 gccaatctgg attgcagact atgtccttgc tagttatgga acaggtgcgg ttatggctgt
     7921 gcctgcccac gaccaacgtg actgggaatt tgccaaacaa tttgaccttc caatcgtcga
     7981 agtacttgaa ggtggaaatg tcgaagaagc tgcctacaca gaggatggcc tgcatgtcaa
     8041 ttcagacttc ctagatggac tcaacaaaga agacgctatt gccaagattg tggcttggtt
     8101 ggaagaaaaa ggctgtggtc aggagaaggt tacctaccgt ctccgcgact ggctctttag
     8161 ccgtcaacgt tactggggtg agccaattcc aatcattcat tgggaagatg gaacttcaac
     8221 agctgttcct gaaactgaat tgccgcttgt cttgcctgta accaaggata tccgtccttc
     8281 aggtactggt gaaagtccac tagctaactt gacagattgg cttgaagtga ctcgtgaaga
     8341 tggtgtcaaa ggtcgtcgtg aaaccaacac tatgccacaa tgggctggtt caagctggta
     8401 ctacctccgc tatattgatc cacacaatac tgagaagttg gctgatgagg acctcctcaa
     8461 acaatggttg ccagtagata tctacgtggg tggtgcagag catgctgttc ttcacttgct
     8521 ttacgctcgt ttctggcaca aattcctcta tgacctcggt gttgttccga ctaaggaacc
     8581 attccaaaaa ctctttaacc aagggatgat tttgggaaca agctaccgtg accaccgtgg
     8641 tgctcttgtg gcaaccgaca aggttgaaaa acgtgatggt tccttcttcc atgtagaaac
     8701 aggggaagag ttggagcaag cgccagccaa gatgtctaaa tcgctcaaga acgttgttaa
     8761 cccagacgat gtggtggaac aatacggtgc cgataccctt cgtgtttatg aaatgtttat
     8821 gggaccactc gatgcttcga ttgcttggtc agaagaaggt ttggaaggaa gccgtaagtt
     8881 ccttgaccga gtttaccgtt tgattacaag taaagaaatc cttgcggaaa acaatggtgc
     8941 tcttgacaag gtttacaacg aaacagtcaa agctgttact gagcaaattg agtctctcaa
     9001 attcaacaca gctattgccc aacttatggt ctttgtcaat gctgctaaca aggaagataa
     9061 gctttatgtt gactatgcca aaggctttat tcaattgatt gcaccatttg cacctcactt
     9121 ggcagaagaa ctctggcaaa cagtcgcaga aacaggtgag tcaatctctt atgtagcttg
     9181 gccaacttgg gacgaaagta aactggttga agacgaaatc gaaatcgttg tccaaatcaa
     9241 aggtaaagtc cgtgccaaac tcatggtcgc taaagaccta tcacgtgaag aattgcaaga
     9301 aattgctcta gcggatgaaa aagtcaaagc agaaattgac ggtaaggaaa tcgtgaaagt
     9361 gattagtgta ccaaataaat tggttaatat tgttgtaaaa taaccaattt atttgctgat
     9421 ttccaacctc aaacagtttc ccaaactgtt tgagccaact aaactcgtta atatcgttgt
     9481 gaaataaggt aggaatcctt cagagtagaa tctggaggat tttttgaatc ttcttatgaa
     9541 agtatggtat actatgggca actataaagt ttgaaaagtg aaaaaaggag aaagctatgc
     9601 cagtaaatga atatggtcaa atgattgggg agtcaatgga aggttataca ccaggtgaac
     9661 tgccttctat tgatttctta gaagggcgtt atgctaggat agaggctctt tcagtggaaa
     9721 agcatgcgga ggatttgcta gctgtttatg ggcctgatac gcctcaggag atgtggacct
     9781 acctttttca ggagccagta gcagatatgg gggagctggt tagcctttta catcagatgt
     9841 tggctcgtaa ggaccgtttt tactatgcaa tcatagacaa ggcgactggt aaggctttgg
     9901 gatctttttc tctcatgcgc attgaccaga ataaccgagt aatagaagtc ggagcagtca
     9961 ctttttctcc agagctaagg ggtacacgga taggaactga agctcagtat ctcctagctc
    10021 gctatgtttt tgaggagcta aactatcgtc gctacgagtg gaaatgcgat gccttaaatc
    10081 tgccatccag acgagctgcg gagcgtttga gctttattta tgaaggaacc ttccgtcagg
    10141 cagtggttta taagggacgt acgagagata cggattggtt gtctatgatt gataaggact
    10201 ggcctcaagt caaagatcgt ttggaaacat ggttgcgtcc tgaaaatttt gataaaaatg
    10261 gacagcagta caagagcttg agagaacttt aagaggtgtt gacatgatta ctattaaaaa
    10321 gcaagaaatt gtcaagctag aggatgtttt acatctctat caggctgtcg gttggacaaa
    10381 ttatacccat caaccagaga tgctggagca ggccttatct cattcattag taatttatct
    10441 ggcacttgat ggtgatgctg tggtgggctt gattcgtttg gttggagatg gattctcatc
    10501 agtattggtt caggatttaa tcgttttacc aatctatcag cgtcaaggaa ttggtagtgc
    10561 cttgatgaaa gaggctttag aggattacaa agatgcctat caagtccagc tggtgacaga
    10621 agagacagaa agaaccttgg gcttctatcg ttctatgggc tttgaaatct tatccaccta
    10681 taattgtata gggatgactt ggatgaatcg taaaaaataa caaaacttgt tttttcttaa
    10741 gcaaaattta aggatggtct agtattatat agtcattaaa taaagacctc ctaactttat
    10801 ttaataaaat cctaaacttt tttcatcaca atctcctaat gaagccaccc aatcaggtgg
    10861 cttttttgcg tggtgaggtg ctggtgatag aaattttttg caaaatagta aaattttaga
    10921 aaagttaagc tagttttaag tttcgtcttg tatcatgtag ttattaaata aagacctcct
    10981 aactttattt aataaaatcc taaacttttc tttttcataa taatctccct taactccacc
    11041 caatcaggtg gagtttttta gctctatttc aggcttttgg ggactattct aaaaataatt
    11101 tttcgatatt tttcggtatt tttcggattt tggtcgggga attggcgggg acttttttag
    11161 cgaatataac taagaaatag gtctgtggtc gcttcagcta gttcaaactc aatttgattg
    11221 taagtgactg ttaattgaag aactggaact actgtaataa tgattttgct tgtctagtag
    11281 tggcgtatta aatgagaagt gacatgtaag attgtctctt cgtttacgaa atcaaaattt
    11341 ctatgaaatt gatagaatcc ctaacgttct cttaatctta accgtcttgt cgtacagcgg
    11401 ttgaagaaaa tgtaaacctt tgacaaaatt cgtgaactat gagataataa aaaggaattg
    11461 agtactagtt ctatatcata ggctagaaaa gaccccaagc tcacgaccaa ataagcttgg
    11521 ggtctttttt gacactattt gtccttgttt agccatttat cgactatacg aagaacgaca
    11581 ccgaccacaa ttggtccgat gatagttttg agtactaatt ccatcatggg ctatctcacc
    11641 tcctttcgta ggcggtgtag cagtgtcgta gaatattata ccacataagt gctaaactta
    11701 ggagtcaccc aatcaggtgg cttttttgtt tgtggcttgg ttttttgata taatagagcc
    11761 atgagtagaa ttttagataa tgagataatg ggggatgagg agttagtaga acgcacgctc
    11821 cgtcctcagt atttacgtga atatatcgga caggataagg tcaaggacca gctacaaatc
    11881 tttattgaag ctgccaaaat gcgggatgaa gcgctggatc atgtgctctt atttgggcct
    11941 ccaggtctcg ggaaaacgac catggccttt gttattgcca acgaactggg agtcaatctt
    12001 aagcagacgt cgggtccagt cattgaaaaa gccggagatc tggtagctat tttgaatgag
    12061 ttagagcctg gggatgtact ttttattgat gagatccatc gtttgccaat gtcagtggaa
    12121 gaggtgcttt atagtgctat ggaggacttc tacatagata ttatgattgg ggctggtgag
    12181 ggtagtcgta gtgttcattt ggagttacca ccttttacct tgattggtgc gacgactcgg
    12241 gctggtatgc tctccaatcc gctacgggca cgttttggga ttacaggcca tatggagtat
    12301 tatgcccatg ctgacttgac agaaattgtc gagcggacgg cagatatttt tgagatggaa
    12361 atcactcatg aggcagcatc tgagttggcc ctacgtagtc gtgggacccc tcgtattgcc
    12421 aatcgtctcc tcaagcgcgt gcgcgatttt gcccagataa tggggaatgg ggtaattgat
    12481 gatattatta ccgataaggc tttgactatg ctggatgttg accatgaagg tttggactat
    12541 gtggatcaaa aaatccttcg taccatgatt gagatgtaca gtggaggacc tgttggtcta
    12601 ggaactcttt ctgtgaatat cgccgaagag cgtgagacag ttgaagatat gtatgagcct
    12661 tacttgattc aaaaaggttt tatcatgcgg acacggtctg gacgggtggc gactgctaag
    12721 gcatatgagc acttaggtta tgaatacagt gaaaaataag caagaaatct tagaggcttt
    12781 tagagaaaat ccagatatga tggccattct gacgatcatc cgagaccttg gtctgaaaga
    12841 ctcgtggttg gcagcaggtt ctgtcagaaa tttcatttgg aatcttttgt cagacaaatc
    12901 cccttttgat catgaaacag atatagatgt gattttcttt gatccagatt tttcttatga
    12961 ggaaacctta ttactggaga aaaagctgcg agaggatttt cctcagtacc agtgggaatt
    13021 gaaaaatcag gtctatatgc atcagcacag tcctcacact gcttcctata ccagttctcg
    13081 tgatgctatg agtaagtatc cagaacggtg tacgacagtt ggactgcgct tgaatgaaga
    13141 atcagatttt gaactctatg caccttatgg tttggaggat attttgaatt ttcaagttcg
    13201 tccaactcct catttcttag aaaatgaaga ccgaatggaa ctctatcaaa cacgtttatc
    13261 caagaaaaat tggcaggaga aatggaaaaa tttgattttt aaaaatactt aaggaaactt
    13321 taagctaggg agtgtacact aagttcataa gttaagaaga ccttaactta aactcctaaa
    13381 actttttcat aataatctcc ctataaaaat aaagtcgccc aatcaggcgg cttatttttt
    13441 tgaaaaatgg gcttggtgcc tgagaataaa tagcttagtg atagaagaaa atggggaaat
    13501 atggtataat aaaacgatag atttttgaat aggaataaga tcatgtttgg attttttaag
    13561 aaagataagg ctgtggaagt agaggttccg acacaggttc ctgctcatat cggcatcatc
    13621 atggatggca atggccgttg ggctaaaaaa cgtatgcaac cgcgagtttt tggacataag
    13681 gcgggcatgg aagcattgca aaccgtgacc aaggcagcca acaaactggg cgtcaaggtt
    13741 attacggtct atgctttttc tacggaaaac tggacccgtc cagatcagga agtcaagttt
    13801 atcatgaact tgccagtaga gttttatgat aattatgtcc cggaactaca tgcgaataat
    13861 gttaagattc aaatgattgg ggagacagac cgcctgccta agcaaacctt tgaagcttta
    13921 accaaggctg aggaattgac taagaacaac acaggattga ttcttaattt tgctcttaac
    13981 tatggtggac gtgctgagat tacacaggcg cttaagttga tttcccagga tgttttagat
    14041 gccaaaatca atccaggtga catcacagag gaattgattg gtaactatct ctttacccag
    14101 catttgccta aggacttacg agacccagac ttgattatcc gtactagtgg agaattgcgt
    14161 ttgagcaatt tccttccatg gcagggagcc tatagtgagc tttattttac ggacacctta
    14221 tggcctgatt ttgacgaagc ggccttgcag gaagctattc ttgcctataa tcgtcgtcat
    14281 cgccgatttg gaggagttta ggaggaaata tgacccagga tttacagaaa agaaccttgt
    14341 ttgcagggat tgccctggct attttcctac caattttaat gattgggggc ctcttgcttc
    14401 agatagcaat cggaatcata gccatgctag ccatgcatga acttttgaag atgagaggtc
    14461 tagagaccat gacgatggag ggcctcttga ccctctttgc aacctttgca ttgaccattc
    14521 ccttggagaa ttacctgact tttttgccag ttgatgggaa tgtggttgcc tatagtgttt
    14581 tgatttcaat catgttagga acgaccgttt ttagcaagtc ttatacgatt gaggatgcgg
    14641 ttttccctct tgctatgagc ttctacgtgg gctttggatt taatgcttta ctagatgctc
    14701 gtgttgcagg tttggacaag gctctcttag ccttgtgtat cgtctgggcg acagacagtg
    14761 gtgcctatct tgttgggatg aactatggga aacgaaagtt agcaccaagg gtatcgccta
    14821 ataaaaccct tgagggtgcc ttgggtggta ttttaggagc aattttagta accattatct
    14881 ttatgatagt tgacagtaca gttgctcttc catatggaat ttacaagatg tcagtctttg
    14941 ctattttctt tagcattgct ggacaatttg gtgatttact agaaagttcg atcaaacgtc
    15001 attttggtgt taaggattct gggaaattta tccctggaca tggtggtgtt ttggatcgtt
    15061 tcgatagtat gttgcttgta tttccaatca tgcacttatt tggactcttt taatcaaaag
    15121 acggaggaaa cgctatgctc ggaattttaa cctttattct ggttttcggg attattgtag
    15181 tggtgcacga gttcgggcac ttctactttg ccaagaaatc agggatttta gtacgtgaat
    15241 ttgccatcgg tatgggacct aaaatttttg ctcacattgg caaggatgga acggcctata
    15301 ccattcgaat cttgcctctg ggtggctatg tccgcatggc cggttggggt gatgatacaa
    15361 ctgaaatcaa gacaggaacg cctgttagtt tgacacttgc tgatgatggt aaggttaaac
    15421 gcatcaatct ctcaggtaaa aaattggatc aaacagccct ccctatgcag gtgacccagt
    15481 ttgattttga agacaagctc tttatcaaag gattggttct ggaagaagaa aaaacatttg
    15541 cagtggatca cgatgcaacg gttgtggaag cagatggtac tgaggttcgg attgcacctt
    15601 tagatgttca atatcaaaat gcgactatct ggggcaaact gattaccaat tttgcaggtc
    15661 ctatgaacaa ttttatctta ggtgtcgttg ttttttgggt tttaatcttt atgcagggtg
    15721 gtgtcagaga tgttgatacc aatcagttcc atatcatgcc ccaaggtgcc ttggccaagg
    15781 taggagtacc agaaacggca caaattacca agattggctc acatgaggtt agcaactggg
    15841 aaagcttgat ccaagctgtg gaaacagaaa ccaaagataa gacggcaccg actttggatg
    15901 tgactatttc tgaaaagggg agtgacaaac aagtcactgt tacacccaaa gatagtcaag
    15961 gtcgttacct tctaggtgtt caaccggggg ttaagtcaga ttttctatcc atgtttgtag
    16021 gtggttttac aactgctgct gactcagctc tccgaattct ctcagctctg aaaaatctga
    16081 ttttccaacc agatttgaac aagttgggtg gacctgttgc tatctttaag gcaagtagtg
    16141 atgctgctaa aaatggaatt gaaaatatct tgtacttctt ggcaatgatt tccatcaata
    16201 ttgggatttt taatcttatt ccgattccag ccttggatgg tggtaagatt gtgctcaata
    16261 tcctagaagc catccgccgc aaaccattga aacaagaaat tgaaacctat gtcaccttgg
    16321 ccggagtggt catcatggtt gtcttgatga ttgctgtgac ttggaatgac attatgcgac
    16381 tcttttttag ataatcgagg aatattatga aacaaagtaa aatgcctatc ccaacgcttc
    16441 gcgaaatgcc aagcgatgct caagttatca gccatgctct tatgttgcgt gctggttatg
    16501 ttcgccaagt ttcagcaggt gtttattctt atctaccact tgccaatcgt gtgattgaaa
    16561 aagctaaaaa catcatgcgc caagaattcg aaaagattgg tgctgttgag atgttggctc
    16621 cagcccttct tagtgcagaa ttgtggcgtg aatcaggtcg ttacgaaacc tatggtgaag
    16681 acctttacaa actaaaaaac cgtgaaaaat cagactttat cttaggtcca actcacgaag
    16741 aaacctttac agctattgtc cgtgattctg ttaaatctta caagcaattg ccactcaacc
    16801 tttatcaaat tcagcccaag tatcgtgatg aaaaacgccc acgtaatgga cttcttcgta
    16861 cacgtgagtt tatcatgaag gatgcttata gtttccacgc taactatgat agtttggata
    16921 gtgtttatga tgagtacaaa gcagcctatg agcgtatttt tactcgtagt ggtttagact
    16981 tcaaggctat tattggtgac ggtggagcca tgggtggtaa ggatagccaa gaatttatgg
    17041 ccattacatc tgctcgtaca gaccttgacc gctgggttgt cttggacaag tcagttgcct
    17101 catttgacga aattcctgca gaagtgcaag aagaaatcaa ggcagaattg ctcaaatgga
    17161 tagtctctgg tgaagatacc attgcttact caagtgagtc tagctatgca gctaacttag
    17221 aaatggcaac aaacgagtac aaaccaagca accgtgttgt cgctgaagaa gaagttactc
    17281 gtgttgcaac gccagatgtt aaatcaatag atgaagttgc agctttcctc aatgttccag
    17341 aagaacaaac gattaaaacc ctcttctaca ttgcagatgg tgagcttgtt gcagcccttc
    17401 tagttggaaa tgaccaactc aacgaagtca agttgaaaaa ccacttagga gcagatttct
    17461 ttgacgttgc tagcgaagaa gaagtggcga atgttgttca agcaggattt ggttcacttg
    17521 gaccagttgg tttgccagag aatattaaaa ttattgcaga tcgtaaggtg caagatgttc
    17581 gcaatgcagt tgtcggtgct aacgaagatg gctaccactt gactggtgtg aacccaggcc
    17641 gtgattttac ttcagaatat gtggatatcc gtgaagttcg tgagggtgaa atttccccag
    17701 atggacaagg tgtccttaat tttgcgcgtg gtattgagat cggtcatatt ttcaaactcg
    17761 gaactcgcta ttcagcaagc atgggagcag atgtcttgga tgaaaatggt cgtgctgtgc
    17821 caatcatcat gggatgttac ggtatcggtg tcagccgtct tctttcagca gtgatggagc
    17881 aacacgctcg cctctttgtt aacaaaacgc caaaaggtga ataccgttac gcttggggaa
    17941 tcaatttccc taaagaattg gcaccatttg atgtgcattt gattactgtt aatgtcaagg
    18001 atgaagaagc gcaagccttg acagaaaaac ttgaagcaag cttgatggga gctggttatg
    18061 aagtcttgac agatgaccgt aacgaacgtg tcggtgttaa atttagcgat agtgacttga
    18121 ttggtcttcc aatccgtatc actgttggta aaaaagcggc cgatggcatt gtagaagtta
    18181 agatcaaggc aactggtgac accattgagg ttcatgcaga taacgtgctt gaaacgcttg
    18241 aaatcctaag taagaaataa aaactataat cagaagaaaa acaaggaaaa aatgtaacta
    18301 gtttttacct tgttttttct gtataatggg agaaatgagt agataaagag gtaaatgtat
    18361 gctaagattt ccaaaggatt ttgtctgggg atcctctact tctggaccgc agacagaagg
    18421 acgtgtagct ggtgacggta agggagacaa tctctgggat tactggttcc aagtggagcc
    18481 aaatcgttac tataatggga ttggttcaga taagacatcg actttttatg aaaattggga
    18541 gcgggatatt gagcttttgt tagagactgg tcacacagcc tttcggactt ctattcagtg
    18601 gtcacggatt tttccacaag gctgtggaaa agtcaaccct caaggtgtgg atttttatcg
    18661 taaggtcttt gaggctatta aggctaaagg aattcgtctg ttagtcaatc tctatcattt
    18721 tgatttacct tttgcccttc aagaggatgg tgatggttgg gaaaataagg cgacagtttc
    18781 agcctatgaa gactatgctc gtttttgttt tgagacttat ggagatttag tggatcaatg
    18841 gattaccttt aacgagccca tcgttcctgt agaatttggt tatttttatg atgcccatta
    18901 tccacataag gtggatgcag aggcagctgt taaggtagcc tatcatacac aattggccag
    18961 cagccgggct gttaaggctt gccatgaact tttgcctgat tccaagattg ggattgtcct
    19021 caacttgaca ccggcttatc cacgtagcca gcatcctgct gatgtcaagg cagctcgtat
    19081 tgcggccctt tttcaggccc aatctttctt agatccatct gtcttgggga cttatccaca
    19141 ggagttggta gaaatcttgc atgaacacgg tcttttacct gatgctacag aggaagagtt
    19201 ggaactcatt cgtgataata cggtggactt ccttggtgtg aactactatc aacctttgcg
    19261 tgttatggct cctcgatttg ctaagcatcc agagagtcca ctcttaccag aacattttta
    19321 cgagcattat gtgatgcctg gacgtaaaat caattctcac cgtggttggg agatttatga
    19381 gcaagggatt tatgacatcg cccaaaatat caaggaaaat tatggcaata ttgagtggat
    19441 gttgactgag aatggtatgg gtgttgaagg ggaagaaaaa ttccgtcaag atggaatgat
    19501 tcaagatgat taccgtattg actttgtaaa aggtcatctt cgtgaacttc accgtgccat
    19561 tgaagatggt gccaactgta agggctactt gatttggacc tttattgact gctggtcatg
    19621 gctcaacagc tataaaaatc gctatggttt ggtcgaatta gacttggaaa cgcaagaacg
    19681 tcgtctgaag aaatcaggcc actggttcaa agaattaagc gataataatg gattttaaaa
    19741 aggactctga ctgattatcc caatcggtca gagtttttat gcttacagga gcttaatttg
    19801 aactatacca atttttactc ttgacaagtg aaagaaacaa gtatatactg tttttactga
    19861 ttctataaaa gatgaattag actataccaa ttttaaggag aaagcacagc ttgcctgtgt
    19921 cgtatatact atgtgtggaa ttgttggtgt tgttggaaac acaaatgcaa ctgatatttt
    19981 gattcaaggg cttgaaaagc ttgaataccg tggctatgat tctgcgggaa tttttgtcct
    20041 agatggtgct gataaccatt tggtgaaggc ggttggtcgt attgcagaat tgtctgccaa
    20101 gacagctggt gttgagggaa caactggtat cggacatact cgttgggcta ctcacggaaa
    20161 accaactgag gacaatgctc acccacaccg ctctgagaca gaacgttttg tcttggtgca
    20221 taatggggtg attgagaact atcttgaaat caaggaagaa taccttgcag gtcaccactt
    20281 caaggggcag acagatactg aaatagccgt tcatttgatt ggaaaatttg cggaagaaga
    20341 agggctctca gttcttgaag ccttcaaaaa agctcttcat attatccgtg gttcatatgc
    20401 ctttgccttg attgactctg aaaatccaga tgtcatctat gtagcgaaaa acaaatctcc
    20461 acttttgatt ggtcttgggg aaggctacaa tatggtctgc tcagatgcta tggctatgat
    20521 tcgtgaaacc aaccaataca tggaaattca tgaccaagag ttggtaatcg tcaaggctga
    20581 tagcgtggaa gttcaagact atgatggtaa cagtcgtgaa cgtgctagct atactgcgga
    20641 acttgacttg tcagatatcg gtaagggaac ttatccttac tacatgctta aggaaattga
    20701 tgagcaacca actgttatgc gtaaactcat tcaagcctac acggatgatg ctggtcaagt
    20761 agtgattgat cctgctatca ttaaggctgt tcaagacgca gaccgcatct acatccttgc
    20821 agctggaaca tcttaccatg caggatttgc ttctaagaaa atgttggaag aattgacaga
    20881 tacaccagtt gaacttggaa tctcatctga gtggggctac ggtatgccac ttctcagcaa
    20941 gaaaccactc ttcatcttta tcagccaatc tggtgaaaca gcggatagtc gtcaagtttt
    21001 ggtcaaggct aatgaaatgg gaattccaag cttaacagtg acaaacgttc caggttcaac
    21061 cctctcacgt gaagccaact ataccatgct ccttcacgca ggtcctgaaa ttgccgtggc
    21121 atcaactaaa gcctatacag cgcaaatcgc agcccttgcc ttccttgcaa aagcagtcgg
    21181 agaagcaaat ggtaatgcta aagcgcaagc ctttgacctg gttcatgaat tgtcaatcgt
    21241 agctcagtct atcgaatcaa ctctttcaga gaaagaaacc attgaagcca aggttcgtga
    21301 acttcttgaa acaactcgta acgcctttta catcggacgt ggtcaagatt actacgtagc
    21361 catggaagca agtctcaaac tcaaagagat ttcttatatc cagtgtgaag gttttgcggc
    21421 aggagaactc aagcacggaa ccattgcctt gattgaagaa ggaacgcctg tcttgtctct
    21481 cttgtcagat ccagttcttg ccaaccatac tcgtggaaat atccaagagg tcgcagcccg
    21541 tggtgccaaa gtcctcacta tcgcagaaga gaatgtagcc aaagataccg acgatatcgt
    21601 ccttacgacc gtacatccat acctctcacc aatttcaatg gtcgtaccaa cgcaattagt
    21661 cgcttacttt gcaaccctcc accgtggctt cgatgtggac aaaccacgta accttgccaa
    21721 gtcagtaacg gtagaataag ctaaaaaagt ctagttatct aggccttttt cttgtgagca
    21781 aattggttgc ttgtactcaa gattcgtgtt atactcttcg aaaatctctt caaaccacgt
    21841 caacgtcgcc ttgccgtagg tatggttact gacttcgtca gttctatcca caacctcaaa
    21901 acactgtttt gagcagcctg cagctagctt cctagtttgc tctttgattt tcattgagta
    21961 ttagaataat ttttcaaatt gaagtacaga gatagataag gagaatcaca atggtagaat
    22021 tgggaatttc aacatttggg gaaataacgg agcttgaagg gactggacaa acttacagtc
    22081 atgctgaacg cattcgccag ttggtggcag agattgagct ggctgacaag gttggtttgg
    22141 atgtatatgg gattggtgag caccatcggg cggattttgc agtatcagcc ccagagattg
    22201 ttctggccgc tggggcagtc aataccaaga aaatccgttt gaccagtgca gtcagcattc
    22261 tgtcaagcat ggacccgatt cgtttgttcc aacagtatgc cactatcgat gctttgtcaa
    22321 atggacgagc ggagattatg gctggaaggg gctctttcac ggaatctttc cctctgtttg
    22381 gttatgactt gaaagactac gactctcttt ttgatgagaa attagccttg cttcagttag
    22441 tcaatgaaaa gaccaagtta gactggcaag gtcgattgac tcaaacgatt gctggtaaag
    22501 aagtttatcc tcgtccagtt caggacaaat tgcccttgtg gatagctaca ggtggtcatg
    22561 tcgaatcaac agtgaagatt gctcaggctg gtctaccgat tgtatatgct attattggtg
    22621 gtaatccacg ttattttaaa aagttgattc aggcttatcg tgagattgga agcgaagcgg
    22681 gtcatgctga caaagacttg aaagtgggag cccattcttg ggggtggatt gcggaagatg
    22741 gtgagcaggc ggtgaaagat tatttccatc cgactaagca agtggtggat gctatttcca
    22801 aagaccgtcc gcactggcag gaattgcgtt atgagcaata tttggagcag gtagggccaa
    22861 atggcgccat gtttgttggc aatccagatc aggtggccga aaaattgatt cgcatgatag
    22921 aggatttagg attggaccgc ttcatgcttc atctaccgct tggttctatg cctcatgacc
    22981 aggttctgag agctattgaa ctcttcggaa cacaagttgc acccaaagta cgagcttatt
    23041 ttgctatgaa agaggcttaa taaaaaatcc taatcaagtt tattaggaca acaaatattg
    23101 tacgaaaatt aatcccccga gctataatgc ttgggggatt tttctatagg agggctagtt
    23161 tagttctctt ttttattttt tagtaagaaa ccgagaccaa ggagcgcaag gaggctgatt
    23221 cctgcaaata ggagtttgtt ttcgtttttg attcctgtat ttggaagttc agcttgtcta
    23281 tctggggttg caggtatatt tttcttgcta gagttttcta ccgattcgtt ttgaaccgct
    23341 tcttttacag atgatgcttg tgcttcttgt gctggttgtt cagcttgtga atcagctgta
    23401 gcttggctag gtttattttc cgcatcagct actttggcat ctggtttagt agaatcaggt
    23461 ctagcttctg gagctgggtc ttgatgttca ggcttggaag gggttgagtc tggtttctct
    23521 tctgcagttg actcatggct agttccattt tgagagactc gaagaacagt agctgtaagg
    23581 gcattcaatt tcaagccttt ttcagtccat tcaagtcctt tcgggttggc aattccgact
    23641 ggtcctgctt ggttttcatc tgccaaaact tccgcatttc ttagatgtgc aaaggcagtt
    23701 cccaaattaa attcgcgagc tttttcatcc gcattgacaa agactgcgta gatatcgccg
    23761 tttggagcag tgatttggta gccaatcact acatcctctt tttccacacc attttggcct
    23821 gggacagtga tgaggtggac acggtctttg atatcttgga gactcttaag tcggaaggca
    23881 tctgtagatt gacgaagggc aatcaaacct ttcatatagt cacggctctt gacattttca
    23941 ggataagctt taccatctgt agccttagtc cagtcaaact tgttgactgc gtcgctagaa
    24001 tcgtaagaat catggatgaa gtaaggatag tcaaatgggt tgccgtcctt atcacgcaac
    24061 aagtgagatt tgtttggaac cttatcctct gctactggag tcttgtaggc tgggtcacgg
    24121 aattgtttag tacgtccata ttcctgaccg gagtggataa atggagttcc ttgagctgtc
    24181 aagaccatga gatttccaag tcgtaaacga cggtggattt cagcatagtt ctcagccttg
    24241 cttgggtctt ttttgataga ctgggcaatg atgtcaaaga gggtcaagtt atcatgggct
    24301 gcgatgtatt ggatgacatc tccagggctg tcagcttcaa agttagttgg ttgagcaatg
    24361 agatttttaa agatggtgtt gacatcacgc ttgccacctg tgataaaggc aggttgacct
    24421 tcgtttggat aaccagattt gaggttgtta cggatgtcat ctgaaaagac agcgacagta
    24481 tcggtatgtt tcatccaatc ttggtcagca gctttagtag gcatgttttc atcaccggca
    24541 taggttctcc aaccttcgcc taacatgatt agatttggat tgagggcgcg tgcagccttg
    24601 taagcttctt cgatagaagc ggcgtcatgg tctcccatca tatcgaagcg gaagccatcc
    24661 actttgtagg tatcaactag gtatttgata gagtcaacta ggaggcgttt ggtcatatgg
    24721 tgggttgtcc ccaagcgtcc accaccaaag ctagttcgag gtgtgccatc ggcatccata
    24781 aagtggtagt agtttggctc taggtcttca aagatatcga ctttggctgt gtggttataa
    24841 acgacatcta ggatagctcc cataccacgt ttgtggattt cgttgatgag gtttttaaat
    24901 tctgcgattc gtttttctgg attcttagga tcgcttgagt acataccagt caaggagaag
    24961 tagttttgag ggtcatatcc ccagttgtag ttgctgttgc ttgaagcata gtcagacaag
    25021 cgttcatggt ttttcaattc attgacaaag tagtaagaca agactggaag gagctggata
    25081 tgggttacac ccaagtcttt gagatagtct agtttttcaa tgaaggcttc aaaagtccca
    25141 aatggtttgg tcaagtcttt tgcaatggca ggatctgaag tgaagtcacg cacatgagct
    25201 tcgtagataa cggcgtcttc acgagtcttg aaattgtgaa tcttaccata agtcaagtct
    25261 tgaggtccga gtttagctgg atctacaaag gcggctttag ccactttatg ggcatcgtca
    25321 atcttggcat cgttgctatt ccaagcagca agagatttag cgtaaggatc gagtgcaaga
    25381 acagttttac cttgacgctc gatttggtat tgataatagt agccagtgaa atctgtgatt
    25441 ccgagtttgt ttgtgctgtc tagagtttgt ttccaagttc ctctttcccc tttttcgaga
    25501 gcgacagttc caactacttt gtcagggtca ttcttgtcgt agacaacaac agaaacctta
    25561 tcagcacttg gtgaccaaag ggtcaaatca acttgttttc cttcttcttt taggtcagct
    25621 cccagtttgc catcatagct gtatgtctca tctttcaggc gccagcttgt tttggtagtg
    25681 aattggtcgg aattgtagct aacagtataa ggatgttttg tgtcagagaa atctccgctg
    25741 taggtcactt tcttaccagc ttcatcgatt gcaacatcgg taatagttac cttgtttcct
    25801 aggtgattag tgatgttgga gtgtttgagg atatcttctt ttttagcacc gacaagtgtt
    25861 gaaaagctac tttcaatgct agaagtgcct acgtgttggg ctcctgtcat acggatatca
    25921 tggacatagt atggatttgt gtaaatcgat tcatcatcgt cttttaggaa aatttggcta
    25981 tgatttttca aatctgtgaa cttataattt tctttacgga ttttcacgtc gtctccttgt
    26041 ttgctctcat ctagtaataa aaatccaaat tctcttgcgg cttcattaag aggaatgtcg
    26101 atatagcggc catatttgcc tgtagccgta aagtctgttc cgtcaggcca ttgagcgcta
    26161 cttggatttt tcacatctcc ccagtaccag agagatttct tgtcatagtt gccatctgtg
    26221 cggtagtagt tgacgcgaac agttcctgca ggctgtggct cgtaagagaa aaccttgtaa
    26281 tcttggtcta accaagcttc gttcattttt ggaactagtt tttctacaga tttatcgccg
    26341 gttagatttt ttccagctgt attgttgatg aggaagctaa ttttcttggc ttgttctccc
    26401 tttaatttga catctaggta atagccgtag tcatctttct tggcatcctt gaaggacaaa
    26461 gctccgtttg gccagttttc agatggtttt tcaacatcgt cccaagtcca tagtccttga
    26521 gcatccttgt tttcttcagg aagttttttg acatggatac ggaagtagtt atcttcgatg
    26581 ggctcttctg ccttagtttc agttgttact ggactagtag aagtagttgg ctcacttgaa
    26641 cgatcttgtc cagtttgtgg tgctggatcg gctgggcttg cagcaggagt tgttggctct
    26701 gttgcaggtt tttcttctgt tttctctagg gaagcgtttg catttccaag tgaagaaata
    26761 tcacttttgt tcttaccaga gccagctgct gtatcagtaa gaggttgggc aagggtggtt
    26821 gtatttctgt tgttgggttc gttagtggtt ggtgtacttt cgtcggatga gatagttggt
    26881 gtagccatgg caagcaagac aaggcttgcg ccgataagga cagaaccagt cccatttttg
    26941 agggaacgga tgctgtagac catttttttc tcagtgtgag atggtgtttt tctcataatg
    27001 attctccaat caataaattt ctatatcagt atagcatgta gtaaaacaat atgcaagcgt
    27061 tttctttgat ttgtgaaaaa aattcttact tttgagaagt tttctgtact attttatata
    27121 tcagtataaa tgacggagat aaaaatgtca cataagccaa gccgtattat taggaagatg
    27181 atgtgttccc agctattttt attcagaaat tgatctctaa cattaccaat aaaaaagaaa
    27241 aatatcttga caaacaaggg aaaattttgt tacaataata gacggtactt tttacttttg
    27301 gtctctcaag agtgtacagg gacgtgctga caaatgttgc aaaagtacac acagatgata
    27361 tctgtcacca agtgtatcat caccaaaaat aaaaaaacac aggagaatgt agatgcctac
    27421 aattaaccaa ttggttcgca aaccgcgtaa atcaaaagta gaaaaatcta aatcaccagc
    27481 tttgaacgtt ggttacaata gtcataaaaa agttcaaaca aacgtttctt caccacaaaa
    27541 acgtggtgtt gcaactcgtg ttggaacaat gacacctaaa aaacctaact cagcccttcg
    27601 taaattcgct cgtgtacgtt tgagcaacct tatcgaagtt actgcctaca tcccaggtat
    27661 cggacacaac ttgcaagagc acagcgtggt gcttcttcgc ggtggacgtg taaaagacct
    27721 tccaggggta cgttaccata tcgtccgtgg tgcacttgat actgcaggtg ttaacgatcg
    27781 taaacaaggt cgttctaaat acggtactaa acgtccaaaa gcataaggaa aggggataaa
    27841 gagaaatgag tcgtaaaaat agagctccaa aacgtgacgt attgccagat ccgctataca
    27901 attcacaact agttactcgt cttatcaacc gcgttatgct tgatggtaaa cgtggtactg
    27961 ctgcttcaat cgtttacggt gcttttgagc aaatcaaaga agctactggc aacgatgcac
    28021 ttgaagtatt tgaaacagct atggaaaaca tcatgcctgt acttgaagta cgtgcacgtc
    28081 gtgttggtgg ttctaactac caagtcccag ttgaagttcg tccagaacgt cgtacaacac
    28141 ttggacttcg ttggttggta acaatcgctc gtcttcgtgg tgaacacaca atgcaagacc
    28201 gtcttgcaaa agaaatcttg gatgctgcta acaacactgg tgcagctgtt aagaaacgtg
    28261 aagatactca ccgtatggct gaagctaacc gtgcattcgc acacttccgt tggtaagata
    28321 ggatgcgaaa gcgttaagaa agtcccagag aaaataggga atcgaagcag gttgcggttg
    28381 caaccaatga gattcatctt tttctccaga cttttagctt gagctcaact aaatcatgat
    28441 gctaggcacg gtaaggatgc aaggtgaaaa taggaaactg acgcagtatt caacgaatac
    28501 aaggagtttt atctttttca cgcagcatcc cgttccagct cacatcggct aactaacttt
    28561 agcccgggtt caaattagct aaatcgatta gtattagcta taactcagct taccatctcg
    28621 taagttgaaa ccaacaatag catgaaaaca ttgagaacgg gtaggtcctg cctatccgtt
    28681 tttattaaaa tcgtgttata atagaataga aatcaaaaat aaataggaga aacaaacctc
    28741 atggcacgcg aattttcact tgaaaaaact cgtaatatcg gtatcatggc tcacgtcgat
    28801 gccggtaaaa caacaactac tgagcgtatt ctttactaca ctggtaaaat ccacaaaatc
    28861 ggtgaaactc acgaaggtgc gtcacaaatg gactggatgg agcaagagca agaacgtggt
    28921 atcacgatca catctgctgc gacaacagct caatggaaca accaccgcgt aaacatcatc
    28981 gacacaccag gacacgtgga cttcacaatc gaagtacaac gttctcttcg tgtattggat
    29041 ggtgcggtta ccgttcttga ctcacaatca ggtgttgaac ctcaaactga aacagtttgg
    29101 cgtcaagcaa ctgagtacgg agttccacgt atcgtatttg ccaacaaaat ggacaaaatc
    29161 ggtgctgact tcctttactc tgtaagcaca cttcacgatc gtcttcaagc aaatgcacac
    29221 ccaatccaat tgccaatcgg ttctgaagat gacttccgtg gtatcattga cttgatcaag
    29281 atgaaagctg aaatctatac taacgacctt ggtacggata tccttgaaga agacatccca
    29341 gctgaatacc ttgaccaagc tcaagaatac cgtgaaaaat tgattgaagc agttgctgaa
    29401 actgacgaag aattgatgat gaaatacctc gaaggtgaag aaatcactaa cgaagaattg
    29461 aaagctggta tccgtaaagc gactatcaac gttgaattct tcccagtatt gtgtggttca
    29521 gccttcaaaa acaaaggtgt tcaattgatg cttgatgcgg ttatcgacta ccttccaagt
    29581 ccacttgaca tcccagcaat caaaggtatt aacccagata cagacgctga agaaactcgt
    29641 ccagcatctg acgaagagcc atttgcagct cttgccttca agatcatgac tgacccattc
    29701 gtaggtcgtt tgacattctt ccgtgtttac tcaggtgttc ttcaatcagg ttcatacgta
    29761 ttgaatactt ctaaaggtaa acgtgaacgt atcggacgta tccttcaaat gcacgctaac
    29821 agccgtcaag aaatcgacac tgtttactca ggtgatatcg ctgctgccgt tggtttgaaa
    29881 gatactacaa ctggtgactc attgacagat gaaaaatcta aaatcatcct tgagtcaatc
    29941 aacgttccag aaccagttat ccaattgatg gttgagccaa aatctaaagc tgaccaagac
    30001 aagatgggta tcgcccttca aaaattggct gaagaagatc caacattccg cgttgaaaca
    30061 aacgttgaaa ctggtgaaac agttatctca ggtatgggtg aacttcacct tgacgtcctt
    30121 gttgatcgta tgcgtcgtga gttcaaagtt gaagcgaacg taggtgcgcc tcaagtatct
    30181 taccgtgaaa cattccgcgc ttctactcaa gcacgtggat tcttcaaacg tcagtctggt
    30241 ggtaaaggtc aattcggtga tgtgtggatt gaatttactc caaacgaaga aggtaaagga
    30301 ttcgaattcg aaaacgcaat cgtcggtggt gtggttcctc gtgaatttat cccagcggtt
    30361 gaaaaaggtt tggtagaatc tatggctaac ggtgttcttg caggttaccc aatggttgac
    30421 gttaaagcta agctttatga tggttcatat cacgatgtcg actcatctga aactgccttc
    30481 aagattgcgg cttcactttc ccttaaagaa gctgctaaat cagcacaacc agctatcctt
    30541 gaaccaatga tgcttgtaac aatcactgtt ccagaagaaa accttggtga tgttatgggt
    30601 cacgtaactg ctcgtcgtgg acgtgtagat ggtatggaag cacacggtaa cagccaaatc
    30661 gttcgtgctt acgttccact tgctgaaatg ttcggttacg caacagttct tcgttctgca
    30721 tctcaaggac gtggtacatt catgatggta tttgaccact acgaagatgt acctaagtca
    30781 gtacaagaag aaattattaa gaaaaataaa ggtgaagact aatccgtcct cactctagaa
    30841 ggaagtcact tagtggcttc cttttgtctt tagaaaatac ctctaaatat ggtaaaatag
    30901 tagaagaata atgtgaggaa aatgaatgtc aaatagtttt gaaattttga tgaatcaatt
    30961 ggggatgcct gctgaaatga gacaggctcc tgctttagca caggccaata ttgagcgagt
    31021 tgtggttcat aaaattagta aggtatggga gtttcatttc gtattttcta atattttacc
    31081 gattgaaatc tttttagaat taaagaaagg tttgagcgaa gaattttcta agacaggcaa
    31141 taaagctgtt tttgaaatta aggctcggtc tcaagaattt tcaaatcagc tcttgcagtc
    31201 ctactatagg gaggttttct ctgaaggtcc atgtgctagt caaggtttta agtcccttta
    31261 tcaaaatttg caagttcgtg ctgagggtaa tcagctattt attgaaggat ctgaagcgat
    31321 tgataaggaa cattttaaga agaatcatct tcctaattta gccaaacaac ttgaaaagtt
    31381 tggttttcca acttttaact gtcaagtcga gaagaatgat gtcttgaccc aagagcagga
    31441 agaggccttt catgctgaaa atgagcagat tgttcaagct gccaatgagg aagcgctccg
    31501 tgctatggaa caactggagc agatggcacc tcctccagcg gaagagaaac cagtctttga
    31561 ttttcaagcg aaaaaagctg cagctaaacc caagctggat aaggcggaga ttactcctat
    31621 gatcgaagtg acgacagagg aaaatcgtct ggtatttgaa ggggttgttt ttgatgtgga
    31681 gcaaaaagtg actagaacag gtcgtgtttt aatcaacttt aaaatgacgg actatacttc
    31741 aagtttttct atgcaaaagt gggttaaaaa cgaggaagag gcccagaagt ttgacctcat
    31801 caagaagaat tcttggctcc gagttcgagg gaatgtggag atgaataatt tcacacgcga
    31861 tttgactatg aacgtacagg atctgcagga agttgttcac tatgagcgga aggatttgat
    31921 gccagaaggt gagcgtcggg ttgagtttca tgctcatact aacatgtcga ctatggatgc
    31981 tttgccagag gtcgaagaga ttgttgcaac agctgctaag tggggacaca aggcggttgc
    32041 tatcacggac catgggaatg tccagtcctt tccacatggc tataaggcgg ctaagaaagc
    32101 gggaatccag ctgatctatg gaatggaagc caatatcgtg gaggaccgtg tccctatcgt
    32161 ctataacgaa gtggagatgg acttgtcaga agcaacctac gtggtctttg acgtggaaac
    32221 gacgggactt tcagctatct ataatgactt gattcaggtt gcggcctcta agatgtacaa
    32281 ggggaatgtt attgctgaat ttgatgaatt tatcaatcct gggcatccct tgtcagcttt
    32341 tactacagag ttaactggaa ttacagatga tcatgtcaaa aatgccaaac cactagaaca
    32401 agttttgcaa gaattccaag aattttgcaa ggatacggtc ctagttgccc acaatgctac
    32461 ctttgacgtt ggctttatga atgctaatta tgagcgtcat ggtcttccaa agattagtca
    32521 gccagttatt gatacgctgg agtttgctag aaacctctat cctgagtata aacgccatgg
    32581 tttggggcct ttgaccaagc gttttggtgt ggccttggaa catcatcaca tggccaacta
    32641 cgatgcggaa gcgactggtc gtctgctttt catctttatc aaagaggtag cagaaaaaca
    32701 tggtgtgacc gatttagcta gactcaacat tgatctaatc agtccagatt cttacaaaaa
    32761 agctcggatc aagcatgcga ccatctatgt caagaatcag gtaggtctaa aaaatatctt
    32821 taagctggtt tccttgtcta ataccaagta ttttgaagga gtgccacgga ttccgagaac
    32881 ggttctagat gcccatcgag agggcttgat tttaggttca gcctgttcag agggtgaagt
    32941 ttttgacgtg gtcgtttctc aaggtgtgga tgcggcggtt gaggtggcca agtattatga
    33001 ctttatcgag gtcatgccac cggctatcta tgcgcccttg attgccaaag agcaggtcaa
    33061 ggatatggag gaactccaga ccattatcaa gagtttgata gaggttggag atcgccttgg
    33121 caagcctgtt ctggctacgg gaaatgttca ctatatcgaa ccggaagaag agatttatcg
    33181 tgaaattatc gtccgtagtt tgggacaggg tgcgatgatt aaccgaacta tcggtcatgg
    33241 tgaacatgcc caaccagcac cacttccaaa ggctcatttt cgaacgacta atgagatgtt
    33301 ggatgaattt gcctttttgg gagaggaact ggctcgtaaa ctggttattg aaaacaccaa
    33361 tgccttggca gaaatatttg aacccgttga agtcgttaag ggtgacttgt atacgccttt
    33421 catcgacaag gctgaagaaa cagttgctga gttgacctat aagaaagctt ttgagattta
    33481 tggaaatccg ctgccagata ttgttgattt gcggattgaa aaagaattaa catccatact
    33541 ggggaatgga tttgctgtga tttatctggc atcgcagatg ctggtgcaac gttctaatga
    33601 acggggttat ttggttggtt ctcgtgggtc tgtcggatct agtttcgttg cgaccatgat
    33661 tgggattacg gaagtcaatc ctctctctcc tcactatgtc tgtggtcagt gtcagtacag
    33721 tgagtttatc acagatggtt cgtacggttc aggatttgat atgccccata aggactgtcc
    33781 aaactgtggt cacaaactca gtaaaaacgg acaggatatt ccgtttgaga ccttccttgg
    33841 ttttgatggg gataaggttc ctgatattga cttgaacttc tcgggagaag atcagcctag
    33901 cgcccacttg gatgtgcgtg atatctttgg tgaagaatat gccttccgtg cgggaacggt
    33961 tggtacggta gctgccaaga ctgcctatgg atttgtcaag ggttacgagc gagattatgg
    34021 taagttttat cgtgatgcag aagtagaacg cctcgctcaa ggagcggcgg gtgtcaagcg
    34081 gacaacaggc caacacccgg ggggaatcgt tgttattccg aactacatgg atgtctacga
    34141 ttttacgcct gtccagtatc cagcagatga tgtcacggct gaatggcaga ccactcactt
    34201 taacttccac gatatcgatg agaacgtcct caaactcgat gtactgggac atgatgatcc
    34261 gaccatgatt cgaaaacttc aggatttgtc tggtattgac cctaataaaa ttcctatgga
    34321 tgacgaaggc gtgatggcac tcttttctgg gactgatgtg ctaggggtaa cacctgaaca
    34381 aattggaacg cctacgggta tgttggggat tccagagttt ggaacaaatt tcgtacgtgg
    34441 aatggtagac gaaacccatc cgacaacctt tgcggaattg cttcagctgt ctggtctgtc
    34501 ccacggtact gacgtttggt tggggaatgc tcaggatctg attaagcaag gaatagcgga
    34561 cctatcgact gttatcggtt gtcgggacga catcatggtt tacctcatgc atgcgggtct
    34621 ggaacctaag atggccttta ccattatgga acgggtacgt aagggtttgt ggctaaagat
    34681 ttcagaagag gagagaaatg gctatatcga agcaatgaag gctaataagg tgccagagtg
    34741 gtatatcgaa tcctgtggga aaattaagta catgttccct aaggcccatg cggcagccta
    34801 cgttatgatg gccttgcgtg tagcttactt caaggttcac catcctattt attactactg
    34861 tgcttacttc tccattcgtg ctaaggcttt tgatatcaag accatgggtg cgggcttgga
    34921 ggtcatcaag cgcagaatgg aagaaatctc tgaaaaacgg aagaacaatg aagcctctaa
    34981 tgtggaaatc gatctctata caactcttga gattgtcaat gagatgtggg aacgaggttt
    35041 caagtttggt aaattagatc tctactgtag tcaggcgaca gagttcctca tcgacgggga
    35101 tacccttatc ccaccatttg tagcaatgga tggtctggga gagaacgttg ccaagcaact
    35161 ggtgcgggcg cgtgaagagg gagaatttct ctctaaaaca gaactacgca agcgtggtgg
    35221 actctcatca accttggttg aaaagatgga tgagatgggt attcttggaa atatgccaga
    35281 ggataaccag ttgagtttgt ttgatgagtt gttttaaaaa attgcttaat aatctattaa
    35341 aagaggctaa cgtatatcca atagatttac attagctttc ttttttgtta aaatagtcta
    35401 tggaaagagg gtgagagtat gtcaaagatg agtataagca tccgtctgga tagtgaggtt
    35461 aaggagcagg cccaacaggt gtttagtaat ctgggaatgg atatgacaac agctattaat
    35521 attttccttc gtcaggcaat tcaatatcag ggactacctt ttgatgttag actagacgaa
    35581 aatcggaagt tgctccaagc gttaacggat ttagaccaaa atcgtaatat gagccagtct
    35641 tttgaatcag tctcagattt gatggaggac ttacgtgctt aagattcgtt atcataaaca
    35701 gtttaaaaaa gattttaagt tggctatgaa gcgtggtttg aaggcagaat tattagaaga
    35761 agttttgaat tttctggttc aagaaaaaga acatcctgcc agatatcgtg atcattcatt
    35821 gacggcatcc aagcattttc aaggagttcg tgaatgccat acccagccag attggctttt
    35881 ggtttataaa gtagacaagt cggaattgat tttaaatttg ctgaggacag gcagtcacag
    35941 tgatttattt taatctattt taagggggtt ctcatgaaac taagaatatt tgcggaagat
    36001 aagccggcta agaaggtatt tgaatatcaa ttagaacttg ctgatcgtac aattcttcta
    36061 tcgacagcac tcttgtcagg tgctattgct ttagcaggaa tcttttctgc tttgagagaa
    36121 aaataaaaat agaaaagaga aaacagaatg gttttaccaa attttaaaga aaatctagaa
    36181 aaatatgcga aattgttggt tgcgaacgga attaacgtgc aacctggtca cactttggct
    36241 ctctctattg atgtggagca acgtgaattg gcacatctaa tcgtgaaaga agcttatgcc
    36301 ttgggtgcgc atgaggtcat cgttcagtgg acagatgatg tgattaaccg tgagaaattc
    36361 ctccatgccc cgatggagcg tttggacaat gtgccagaat acaagattgc tgagatgaac
    36421 tatctcttgg agaataaggc tagccgtctt ggagttcgtt catctgatcc aggtgccttg
    36481 aacggagtgg acgctgacaa gctttcagct tctgctaaag ctatgggact tgccatgaag
    36541 cctatgcgta tcgcaactca atctaacaag gttagctgga ctgtagcagc tgcagcagga
    36601 cttgagtggg ctaagaaagt cttcccaaat gctgcgagcg acgaagaagc agttgatttc
    36661 ctttgggacc aaattttcaa aacttgccgt gtctacgaag cagatcctgt taaggcctgg
    36721 gaagagcatg cagctatctt gaagagcaag gccgatatgc ttaataagga gcaattttca
    36781 gcccttcact acacagcgcc aggaacagat ttaacacttg gtttgccaaa gaaccatgtt
    36841 tgggaatcag ctggtgctgt caatgcacag ggcgaaggat tcttgccaaa tatgccgaca
    36901 gaagaggtct tcacagcacc tgacttccgt cgtgcagatg gttatgtcac ttctacaaaa
    36961 ccgcttagct acaacggaaa tattattgaa ggcattaagg tgacctttaa ggatggacaa
    37021 atcgtagata tcactgctga gaagggtgat caggttatga aagaccttgt ctttgaaaat
    37081 gcgggtgcgc gtgccttggg tgaatgtgcc ttggtaccag atccaagtcc aatttctcag
    37141 tcaggcatta ccttctttaa cacccttttc gatgaaaatg cgtcaaacca cttggctatc
    37201 ggtgcagcct atgcgactag cgttgttgat ggagcggaga tgagcgaaga ggagcttgaa
    37261 gctgcagggc ttaaccgttc agatgttcac gtagacttta tgattggttc taaccaaatg
    37321 gatatcgatg gtattcgtga ggatggaacg cgggtacctc ttttccgtaa tgggaattgg
    37381 gcaaattaag gagataatat gttaggaagt atgttcgttg gtctcctagt gggattttta
    37441 gcaggtgcta tgaccaatcg tggagagcga atgggatgtt ttggaaaaat gtttctcggt
    37501 tggatcggag cctttctagg tcacttgctc tttggaactt gggggccagt tttatcagga
    37561 acagctatta tcccagctgt tttaggtgcc atgattgtct tagctatttt ttggagacga
    37621 ggaagttaat ttcctaaatc tgatactcaa tgaaaatcaa agagcaaact aggaaactag
    37681 ccgcaggttg ctcaaagcac tgctttgagg ttgcagatag aactgacgaa gtcagtaaca
    37741 tatatgcggc aaggcgacgt tgacgcggtt tgaagagatt tttgaagagt atgaaacgaa
    37801 aaggaggttg gtcattgtac tagcctcctt ttgatatgat ataatagttc tatgagatta
    37861 gataaatttt tagttgcctg tgcggtggga agtcggactg aggtcaaaaa cttgctcaag
    37921 gctgggcgcg tgactgtaaa tggtaaaaaa gaaaaatcag ctaaattgca gattgatgaa
    37981 aaaatagatg agattcgctt tgatgggcaa gtgttggagt atgaagagtt tgtctactac
    38041 atgatgaaca agcccaaagg agttatctca gcgactgagg atcccaagca cagaaccgtt
    38101 ctggacttgt tggatgactt ggcgcggagt aaggaagttt ttccagtagg acgcttggat
    38161 attgacacgc atggtctttt gctcttgacc aataatggtc agctggctca tgttcttctt
    38221 tctcccaagc gtcatgtgga caagacttat caggctcagg tcaagggaat tatgacccaa
    38281 gaagatgtgg agacatttat caagggcatt ccgctcaaag actttacctg tcagcccgct
    38341 agactggaga ttctttccac agatgcagaa aagaatcaga gccaaatccg tgtgaccatt
    38401 gcagaaggga agtttcatca gatcaagcgt atggtgggct actgtggcaa ggaagtggtg
    38461 gacttgcaac gattgactat gggaacttta gtattagatg agaacctgga acgaggggaa
    38521 tggcgtcgct tgaccaagga agaattagaa attctccgcg ctaatattat ttaatttagt
    38581 ttaatactca atgaaaatca aagagcaaac taggaaacta gccgcaggct gtacttgagt
    38641 acggcaaggc gacgttgacg tggtttgaag agattttcga agagtataaa ttcgaaaaag
    38701 gtgagggaga atgtccttac cttttatgtt ttttagttgc ttcctttgtg aaaagagtta
    38761 taatagactg tagaataaaa ggaggaatct atgaacgcga ttcaagaatc atttactgat
    38821 aaactatttg ccaactatga agcaaatgta aaataccaag cgattgaaaa tgctgccagc
    38881 cacaacggaa tttttgcagc tctggaacgt cgccaaagcc atgtagacaa cacacctgtt
    38941 ttctcattgg atttaaccaa ggacaaggtc actaaccaga aagcgtctgg tcgttgctgg
    39001 atgtttgcgg ctctcaacac cttccgccac aaactcatct cgcaatacaa attggagaac
    39061 tttgagttgt cacaagccca cactttcttc tgggataagt atgagaaatc aaactggttc
    39121 ttggagcaag tcattgcgac ttcagaccaa gaattgacta gccgcaaggt tagcttctta
    39181 ctccaaacac ctcaacaaga tggtggtcaa tgggatatgg tcgtttccct ctttgaaaaa
    39241 tacggtgtcg tgcctaagtc agtttatcct gagtctgttt catctagcag cagtcgtgag
    39301 ctaaatgcga tccttaataa attgcttcgt caagatgctc aaatcttgcg tgatttgctt
    39361 gtttctggtg cagatcaagt gactgttcaa actaagaaag aagacctctt gcaagaaatc
    39421 tttaactttc ttgctatgtc attaggactt ccaccacgca agtttgactt tgcttatcgc
    39481 gataaagata acaactacaa aagtgaaaaa ggaatcacac cacaagagtt ctacaagaaa
    39541 tatgtcaatc ttcctttaga agactacgtt tctgttatca atgctccaac tgctgataaa
    39601 ccttacggaa aatcttacac agttgagatg ttggggaatg tggttggtag ccgtgcagtt
    39661 cgctacatca acgttccaat ggagcgcttg aaagaattgg cgattgccca aatgcaagca
    39721 ggtgagactg tttggtttgg ttctgatgtc ggccagctca gcaaccgtaa ggctggcatc
    39781 cttgcgacag atgtttatga ctttgaatca agcatggaca ttaaacttac tcaagacaag
    39841 gctggacgtt tggactatag tgaaagcttg atgacccacg ccatggtctt gacaggtgtt
    39901 gacttggacg aaaatggtaa atcaaccaag tggaaggttg aaaactcatg gggagacaag
    39961 gtcggtacag atggttactt tgttgcctca gacgcttgga tggacgaata cacataccaa
    40021 atcgttgttc gtaaggaatt gctgacagca gaagaacaag ctgcctatgg agcagaacca
    40081 atcgtacttg caccatggga tccaatggga gccttggctg aataaaagca tagaaaaaag
    40141 gaatcagatt ttagaacctg gttccttttt agttgcttga ttacatgatg tgaagaacat
    40201 gtgccacaat acccactgcg aagagggcaa ggataatagt gattggagat acttttttct
    40261 taagtaagta catgcaaagt aaagtaagga gtagtcctga taatccagga atcaacatat
    40321 ccaagttttg ttggaaagta gtaacttttt caggagtttg agacaatcct tgtcctactt
    40381 gtgcgaatgc ttcttggata cctttagacc cttctggcaa tttatcccaa tggatataag
    40441 ccttttcatc tagttgaact ttagaaacat cgaaagcaaa tttaatattt acccagcgtt
    40501 gaacaaggac agcaagaatg aacatcccaa ggatagaagc tcctttagtg atatcttgaa
    40561 ggataccacc agacatatct ttagtgattt ctgatccagc cttgtatcca atctcttgaa
    40621 cataccacaa gaatgacata cgaatcaagt tccatgcaac aaagaagagg agtggaccca
    40681 agatattgcc agtaagggca agtgaagcac cgagagatcc aaggattggg cgtactgtaa
    40741 accagaatac tgggtcaccg ataccagcaa gaggtcccat cataccgatt ttaacccctt
    40801 ggatagcagc gtcatcgatt tccacaccgt tagcacgttc ttcttcaagc gcaagagtaa
    40861 cccccatgac tggagcagct acgtatggat gagtgttgaa gaactcaagg tgacgctcaa
    40921 gagcagcgat ttgatcttct tttttagtat agagtttttt gatagctgga atgagtgtat
    40981 aagcccagcc caagttttgc atccgttcaa agttccaaga cccttgtaag aaggttgaac
    41041 gccaccaaac ttttttacga tctgatttag ttaattgaag tttttcagtc atgatgtttt
    41101 cagtcctttc ttatcttagt agtcttctag gatatcgccg attgggtcgt tagaagttgc
    41161 ggctcctccg ccaccatttc caccagtttt agaaaggtga aggtagataa gagcgatagc
    41221 aacaccgata gcaccgaatc cgattagagt aatatctgac acagcagcga gaacgaaacc
    41281 aagagcgaag aatggccata cttcacgagt tgccatcatg ttgataacca tggcgtaacc
    41341 aacggcaacg accataccac caccgatagc cataccatct ttgagccagt ctggcatggc
    41401 actaaggata ctttgtacag tttcagttgg taccataagg agaagagctg caggaagcgc
    41461 gatacgaagt ccttggaaaa gtagcgcaat gaaatgcgca cgctccacag cgccgaagtc
    41521 acctttttta gcggcagcat ctgcagtatg aaccaaacca actgaaattg tacgaacaat
    41581 cattgtcaag aaaagtccag ctacggcaag agggatagca accgcttggg caacaccgat
    41641 accagtcttg gtaaagtcac caccaagaac catgataatg gcagcagcga cagaagcaag
    41701 tgcagcatca ggagcgatag cagcaccgat atttgaccaa ccaagggcaa tcatttgaag
    41761 cgatccaccg aggataatcc ctgcttccaa gtgacctgtt acaagcccaa taagggtaca
    41821 ggctacaagt ggttggtgaa attggaactg gtcgaggatg ccttcaagac ctgcaaagaa
    41881 ggctacaacg actactaaaa ccatagaaat aatagacatg tttaaaatcc tttcataaat
    41941 aatggcttat ttgacattgg ctttgttaat caagtcaaac aaatcttttt tagaatcatt
    42001 tggtacttta cggacatcaa attcaacacc caagtcacgc attttttcaa atgtagcaac
    42061 atcttctttg tccatagaca aaacggtatt gaccaatgtt ttacctgttg agtgagccat
    42121 agaaccaacg ttaagagtct tgattggcac gccgccttcg atggcacgaa gggcatcttg
    42181 aggtgtttca aacaagataa gggcatgtgt ttctccaaaa cgtgggtctt ttgaaatctc
    42241 aatcagtttt tgaattggaa ccacgttagc cttgacatta cctggagctg cttgtttaat
    42301 caattcttta cgaaggtcgt ctttagccac gttatctgaa gcaacgatga tacgatttgc
    42361 ttttgaatct ggagtccaag cagttgcaac ctgaccgtga agtagacgtg tgtcaagacg
    42421 ggcaagattg attttcaatt taccgtctcc gataacagtt ccttctggga tagcagtttg
    42481 ggcaactgga gcagctgcag cgcttgcaac ttcttcaact ggatttagct cttctggaag
    42541 agctttgatg ccatctttgg cttctttaat gatattagca gcgacttttt ctacacctgc
    42601 agcagcgtcc atgaggcgct ctgtgtaggc ttgaatcaac atcggtaagt taagtcctgt
    42661 gatgatggca aacttacgct caggattttc tcccatcacg cgactagctt ggttaaatgg
    42721 agaaccactc caaaggtcag ccaaaactag aacctcatct tctgcgtcaa atgcagcaac
    42781 agcgttatta aacttagcgt atagatcatc aggaccttca tttggcataa aggtcacaac
    42841 ttgaaccttt tcttgttcac caaagatcat agatcctgac tgatgaatac ccgcagcaaa
    42901 ttcgccgtgg ctcgcaataa tgattccgat actcattatt gtcattcctc cttttttgtt
    42961 ttagttttca tttaagaaaa ctttaagact gtttaagtat aaaccgtttt cataaaaaaa
    43021 gcaactattt atcataaaaa attaaaaaat ttttattttt atatgttgat atgttgagtt
    43081 tttgaggagt aatcttgaat tcttatttaa aatttaatat aaaaaagttg gaagaagctt
    43141 ccaactttta aaataggttt ctattagatt agtgggtgaa gtcgagtacc atacgtcctt
    43201 ggatttggcc tttttccatt tcgtcgaaaa tggcaacagc atcttctact ggacgttttt
    43261 gaacaactgg gactaccaga ccttctgcac caaattggaa ggcttcttct aagtctttac
    43321 gagttccgac aagagaaccg atgacttgga ttccatcgag gactgtttta acgatgctga
    43381 gttccatcgt ttcagaagga agaccaacag cgacgacgcg accaccagca cgaatggagt
    43441 caacagcctg gttgaaggca actttagaca cagcagttac gacagctgaa tgagctcctc
    43501 catcagtttt ttctttaatg agtccagcta catcttcaac ttcgaggccg ttaatcacaa
    43561 tgtcagcgcc tacttctttt gcaagggcaa gtttgtcatt gttgatatcg actgcgataa
    43621 catgagcatt gaatactttt ttagcgtatt gaacagcgag gttaccaagt ccaccagcac
    43681 cgtaaagaac aacccattgg cctggttcaa cttttgcttc tttgatagct ttataggttg
    43741 ttactccagc acatgtgata gaagaagctt gggctggatc aagtccgtca ggaactttga
    43801 cagcatagtc agcagttacg atacattgtt cagccatacc accgtctact gagtagccag
    43861 catttttcac tgtacggcaa agggtttcgc gaccagttgt acagtattcg caagtgccac
    43921 atccttcaaa gaaccaagca acgctgacgc ggtcaccgac tttaaggctt ttcacatctg
    43981 gagcaatctc tttaacgata ccgatacctt cgtgcccaag aacacgtcct gggacttgac
    44041 caaagtcacc atgagcaacg tggaggtcgg tgtggcaaac gccacagtat tcaacttcta
    44101 caagtgcttc cccagtttca agtggacgga gtactttttc ttcaatagca acaccagtgc
    44161 tttctggatt tacaacaaca gctttcatag ctatcctcct tgatattgac cgagaacagg
    44221 gacaacggga ctggattgat tttttgtcaa cagagtcgag tgtgacgagc tctcttgtat
    44281 ttatatgtga agtatatcac aaaagaaagc cttttccaag gttttggaga caaaaagtag
    44341 aacaatcgat taactggttg atgagactgt gaaaagagca caaagaccag cttgcaagct
    44401 ggtcatactc ttcgaaaatc tcttcaaacc acgtcagctt catctacaac ctcaaagcag
    44461 tgctttgagc aacctacggc tagcttccta gtttgctctt tgattctcat tgagtatcag
    44521 tataggttat aagaataagt cttgtagggt tttggcaacc ccatcttggt cgttggtaag
    44581 ggaaatttgc tcatctgcat aaggaagtag ctctggattg gcatttttca tggcataacc
    44641 cttcccagca aaagcgagca tttcggtatc attgtgttca tctccaaagg caatcaaatc
    44701 ttttttgtca cgattcatta tcttgagcaa gtagtccaaa gcaaaggcct tgttgacacc
    44761 ttttggggta cattcaagga tattgagcgg acctccccag gtattgatag aaagttgatg
    44821 ctggtagaag gcgttcatgt cttttgccaa ggcatatttg tcactggctc tggtctgcaa
    44881 gaggatacag ttagggtcct tggtcaccaa ttcaggctgg aattgatctt caggctggaa
    44941 agcttctaca ccaaatagtt tgggattggc aatctcttca ttgggatttg taatgtagaa
    45001 ttttttacga tattctccag cgataaaatc ggcttgaatg tcctctgaac gttgaaccat
    45061 atctagcaga tattttttgt ctacagtcaa acacttttca aaatcccaaa cttggtctgg
    45121 taaatgagta agggatccgt tgaagttaat cataggagtg tctaagccca gttcacggta
    45181 aaaatctttt gacatacggt aagggcgacc tgtcgtaata ataacctgat ggcctttttc
    45241 agcaactttt ttgatggttt ttttggtaaa gtcagaaatt tgactgtctg agttgagcag
    45301 ggttccatcc aggtcaactg caataatttt tttcgtcata tggacctttc tagtgtgttt
    45361 tcagataaga tgtcttctat tataacagaa agcaggcaga aaagcagatt ccaaacaaaa
    45421 aatgaaattg gattaatttc ttaaacaaat caaacaaaga cattgaaaaa gtgaatgata
    45481 aatgatataa ttctattatt gttcgtaaaa attaaaagga gattgatgat ggacaaatta
    45541 tttaaactaa aagagaacgg tacagacgtt cgtacagagg ttctcgctgg tttaacaact
    45601 ttctttgcaa tgagctatat tctctttgta aacccacaaa tactttcaca aacaggaatg
    45661 cctgctcagg gtgtcttcct agcgacgatt attggtgcag tagcgggtac cttgatgatg
    45721 gctttttatg ctaacttacc ttatgcccaa gcgccaggta tgggactcaa tgccttcttt
    45781 acctttacag ttgtattcgg gcttggttat tcttggcaag aagccctagc tatggtcttc
    45841 atctgtggga ttatttcatt gattattacc ttgacaaagg ttcgtaaaat gatcattgaa
    45901 tcgattccca atgctcttcg ctcagctatt tcagctggta tcggtgtctt ccttgcctat
    45961 gtagggatta agaatgctgg acttttgaaa ttcacgattg atccaggcaa ctatactgtt
    46021 gtaggagaag gggctgacaa agctcaagca acgattgcag caaactcttc agcagttcca
    46081 ggattggtca gctttaataa tccagctgtt ttagtggctc ttgcaggact tgccattact
    46141 atcttctttg tcatcaaagg gattaaaggg ggaattattc tctctatctt gacaacaact
    46201 gttcttgcta ttgcagttgg tttggttgat ttgtctagta tcgattttgc taataaccat
    46261 gttggtgcag cttttgaaga tttgaagaca atctttggtg cagctcttgg ttcagaaggt
    46321 ttaggagctt tggtttcaga tacagctcgc ttgcctgaaa ctctgatggc cattcttgcc
    46381 ttctcattga cagatatttt tgacacaatt ggtaccttga tcggtacagg tgaaaaagtt
    46441 ggtattgtag cgacaaatgg tgaaaatcac caatcagcca aattggataa ggctctttac
    46501 tctgatttga ttggaacgac agtcggtgcc attgcaggta cttcaaacgt aacgacttat
    46561 gttgagtctg ctgctggtat cggtgcaggt ggacgtactg gtttgacagc cttggttgta
    46621 gctatctgtt ttgcgatttc aagcttcttt agcccacttc tagcgatcgt accaacagcg
    46681 gctacagctc caatcttgat tatcgttggg attatgatgc ttggtagctt gaaaaatatc
    46741 cattgggatg atatgtctga agcagttcct gccttcttca catctatctt tatgggattc
    46801 agctactcta tcactcaagg gattgcagtt ggtttcttga cttacacttt gactaagctt
    46861 gttaaaggtc aagttaaaga tgttcatgcc atgatttgga ttttggatgc cttgtttatc
    46921 cttaactaca ttagcatggc cttataatag aatgacccag ggggatttcc cccctttttt
    46981 aatacaaagg agataggtga tgaaagagaa aaatatgtgg aaagaattgt tgaatcgtgc
    47041 aggctggatt ttggtctttt tacttgccgt ccttttatat caggttcccc tagtggttac
    47101 ctctattttg actttaaaag aagtagccct gctacagtca gggctgatgg ttgctggcct
    47161 ttcaattgtg gttctggctc tatttattat gggagctcgt aaaaccaagt tagctagttt
    47221 taatttttct ttttttagag ctaaagattt ggcacgtttg ggtttgagtt atttagttat
    47281 tgtcgggtca aatatacttg gttctatctt gttgcaactg tcaaatgaga cgacaacagc
    47341 taaccagtct cagattaatg atatggttca aaatagttcg ttgatttcca gtttcttctt
    47401 gctagccttg cttgctccga tttgtgagga aatcttgtgt cgtgggattg ttcctaaaaa
    47461 gattttccga ggcaaggaga acttgggatt tgtagtcggt acgattgtgt ttgctttatt
    47521 gcatcaacca agtaatttac cttctttatt gatttatgga ggtatgtcga cagttctatc
    47581 ttggacggcc tacaagaccc aacgtttgga aatgtcgatc ttgcttcaca tgattgttaa
    47641 tgggattgct ttctgtttgt tggctcttgt ggtgattatg agtcggacat taggaatttc
    47701 tgtttaaaag cttttatgta gaaaccgacc tctttctact agggaaagat gaatgcaatc
    47761 gtgtccatct ttttcttttt atggtaaaat agaaaaataa taagatgaaa agccttgagg
    47821 gagtgaccga tatgtcaagt aaagccaatc atgcaaaaac agctatttgc ggaattatca
    47881 atgtaacccc agactccttt tcggacggtg gtcaattttt tgctcttgag caggcactcc
    47941 agcaggctcg taaattgata gcagaaggag ccagtatgct cgatatcggc ggagaatcga
    48001 ctcggccggg cagtagctat gttgagatag aagaggaaat ccagcgtgtt gttccagtga
    48061 tcaaagcgat tcgcaaggaa agtgatgtcc tcatctctat tgatacttgg aagagtcaag
    48121 tagcagaggc tgctttggct gctggtgccg atctagtcaa tgatatcact ggtcttatgg
    48181 gtgatgagaa aatggctcat gtggtagctg aagcgagagc gcaagtggtc atcatgttta
    48241 acccagttat ggctcggcct cagcatccta gttcgcttat cttccctcat tttggttttg
    48301 gtcaaacctt tacagaaaaa gagttagcgg actttgaaac attgccaatc gaagaattga
    48361 tggaggcttt ctttgaacga gcactagcga gagcggcaga agctggtatt gcaccagaaa
    48421 atatcctgtt ggatccagga attggctttg gtctgaccaa gaaagaaaat ctgcttcttt
    48481 tacgggacct ggataaacta catcagaagg gctatccaat ctttctcgga gtgtcgcgca
    48541 agcgatttgt catcaatatc ctagaggaga atggttttga agtcaatcct gagacagagc
    48601 ttggtttccg aaatcgggac acggcttcgg ctcatgtaac tagtatcgct gcgagacagg
    48661 gtgtagaagt ggtgcgcgtg catgacgtag ctagtcacag gatggcagtt gaaattgcct
    48721 ctgccattcg tctggctgat gaagcggaaa atttagattt aaaacaatat aaataagatg
    48781 aaagaaattg aaaacaatca gtggattgct aactaccgga cggatcaacc gcattttggc
    48841 ttggaacgaa tggtggaact gttagctttg cgtggcaatc cccatctcaa actcaaggtc
    48901 ctccatatcg gagggactaa cggcaagggc tcgactattg cttttttgaa aaagatgcta
    48961 gaaaagctag ggttgagagt tggcgtgttt agctcgccct atctcattca ttacacagac
    49021 cagattagca tcaatgggga atcgatctca gaagcgaggc tagaagctct catggcagac
    49081 tatcagtctt tgctggaggg agaagcggtc gccaatttac agggcacaac cgagtttgag
    49141 attatcacag ccctggccta tgactacttt gcctcagagc aagtagatgt ggccatcatg
    49201 gaagttggca tgggtggact tttggatagt accaatgtct gtcagcccat tttgacagga
    49261 attacaacta ttggcttgga tcatgtggcc ctacttggtg acaccttgga gtccatagca
    49321 gagcagaagg caggtattat caaacaaggg atgcccttgg taacagggcg tattgctcca
    49381 gaagccttag ctgtgattga ccgcattgcg gaagagaaag atgcgccgag acttgcctac
    49441 gggacagatt atcaggttcg tcatcaagaa agtgtggtga caggggaagt ctttgactat
    49501 acaagtgctg tcagacaagg ttgcttccag actagcctgc ttggtttgta ccaaatagag
    49561 aatgctggga tggccatagc tttacttgat actttttgtc aagaagatgg tcgagagcta
    49621 gcaagcaatg actttcttgg tcaagccttg gaagaaacaa gttggccagg gcgtttggaa
    49681 atcgtgtcaa gagatccctt gatgattttg gatggagccc acaatcccca tgctatcaag
    49741 gccttgttgg taaccttgca agaacgtttt gcggatcatc ataaggaaat cctcttcact
    49801 tgtatcaaaa ccaaagcctt ggaggatatg ttggacttgc tgggagccat gccagatacc
    49861 gagcttactc taacacattt tgcggatagt cgggcgacgg atgaaagcgt gctgaaagag
    49921 gcagctaagg ctagaaatct cagctaccaa gattggcatg attttctaga gcagaatttg
    49981 acagataaaa aagaagagaa acaaacagtt aggattgtca caggttcctt gtatttcttg
    50041 agccaagtga gggcctatct gatggagagg aagaacgaga atggatacac aaaagattga
    50101 agcagctgta aaaatgatta tcgaggctgt aggagagaac gctaatcgcg agggcttgca
    50161 ggaaacacct gctcgtgtag cccgtatgta tcaagagatt ttttcaggtc ttggtcaaac
    50221 agcagaggaa catttgtcaa aatcctttga aattattgac gataatatgg tggtagaaaa
    50281 ggatatcttt ttccatacca tgtgtgaaca ccacttcttg ccattttatg gtagagcgca
    50341 cattgcctac attccagatg gtcgtgtggc aggcttgtct aagctagccc gtacggttga
    50401 agtttattcg aaaaaaccac aaattcaaga acgtttgaat atcgaagtgg ccgatgcctt
    50461 gatggactat ctaggtgcta aaggagcctt tgttgtcatt gaggcggaac atatgtgtat
    50521 gagtatgcgt ggtgttagaa aaccaggcac tgcaaccttg acgacagtag ctcgtggtct
    50581 atttgaaaca gataaggatc tccgtgacca agcttatcgt ttaatggggc tataaaaaga
    50641 atccgcttca agcggatttt tctagaaagg aatcattatg gatcaactgc agattaagga
    50701 tttggaaatg tttgcctatc atggtctttt tcctagtgag aaagaattgg ggcagaaatt
    50761 tgtcgtttca gccatcctat cctatgatat gaccaaggca gctacagact tggatttaac
    50821 agcctctgtc cattacggag aattgtgtca gcagtggacg acttggtttc aggaaacgag
    50881 tgaagatttg attgaaacgg tagcctataa actggtggaa cgtacctttg agtcttatcc
    50941 tcttgtccaa gaaatgaagt tggaactgaa aaaaccttgg gcaccggtgc atttgtcact
    51001 agatacttgc tcggtaacca ttcatcgccg caagcaacga gcctttatcg ccctaggaag
    51061 caatatggga gataaacaag caaacttgaa gcaagccatt gacaaactgc gagctcgtgg
    51121 catccatatt ctcaaagagt ccagtgtctt agcgacggag ccttggggtg gagtggagca
    51181 ggatagcttt gccaatcaag tggttgaggt ggaaacctgg ctaccagcac aagacttgtt
    51241 agaaaccttg ttagccattg agtcagagct gggacgggtg agagaagtgc attggggacc
    51301 tcgtttgatt gatttggact tgctctttgt ggaggaccag atcctttata cagacgacct
    51361 catattgcct catccttaca tagcggaacg cctttttgtc cttgagtcct tacaggaaat
    51421 tgcgcctcat tttatccatc cgatattaaa acaaccgatc cgcaacttgt atgatgcttt
    51481 gaaaaaatag aaaaactcta gttttcagtc acttgcaact gaaggctaga gtttttatac
    51541 tcttcgaaaa tcaaattcaa accacgtcag cgtcgcctta ccgtactcaa gtacagcttg
    51601 cggttagctt cctagtttgc tctttgattt tcattgagta ttaaaatagg tcattttctt
    51661 ctgggaggag gatagtttct ctaccgtcca tgtctaaaac cagtactctt gggggataac
    51721 gagggtcgaa aggatggtta aagtcaaaat caatggctgt agggaggtgt tgacttgaaa
    51781 agtggaaggt aatctttcct tggttattaa gcaattgaaa ctcgagttct tcttccaatt
    51841 caaagacatt ttttaagaaa tgatcgatga tataccaaaa agagtcaatg atgtcatcgg
    51901 gcaagctggt aacaatgcca aaactagcag accgcatgtg ggtattggta aaagccatat
    51961 ctctgtcccc tttcttttcc cttatcatac agcaaatagg attaaaaatc aagaaaaggt
    52021 gattttttga aaaggatttt aactacaggg aaaaagaagg aaaaaaattc ccaaaaatct
    52081 accgaagtta ataggtaaat tcccaaatta acttgattat ataactttca gttactttga
    52141 gaagttaccg aaaaatattt ttcatatcta ttgactttta ggggtaaaat ttggtatgat
    52201 agtaggcggt attgtttacc ccatttgaaa ggccccggaa ccttccaaat acttttcgat
    52261 gggaaggaac acccatcacc gtaaacaaaa atcgaactat atataggaga aatcatgaac
    52321 aaaacaacat ttatggctaa accaggccaa gttgaacgta aatggtacgt agttgacgca
    52381 actgatgtac cacttggacg tctttctgca gtagttgcta gcgtacttcg cggaaaaaac
    52441 aaaccaacat ttacaccaca cactgataca ggtgacttcg tgattgttat caatgctgaa
    52501 aaagttaaat tgactggtaa aaaagcaact gataaaatct actacactca ctcaaaccac
    52561 ccaggtggat tgaaacaaat ctctgcaggt gaacttcgtt ctaaaaatgc agtacgtttg
    52621 attgagaaat cagttaaagg tatgcttcca cacaatacac ttggacgcgc tcaaggtatg
    52681 aagttgaaag tatttgttgg agctgagcac actcacgctg cacaacaacc agaagttctt
    52741 gacatttcag aacttatcta aggaaaggaa caataaagta tgtcacaagc acaatatgca
    52801 ggtactggac gtcgtaaaaa cgctgttgca cgcgttcgcc ttgttccagg aactggtaaa
    52861 atcactgtta acaaaaaaga tgttgaagag tacatcccac acgctgacct tcgtcttgtc
    52921 atcaaccaac cattcgcagt tacttcaact gtaggttcat acgacgtttt cgttaacgtt
    52981 gtaggtggtg gatacgctgg tcaatcagga gctatccgtc acggtatcgc tcgtgccctt
    53041 cttcaagtag acccagactt ccgcgattca ttgaaacgcg caggacttct tacacgtgac
    53101 tcacgtaaag ttgaacgtaa gaaaccaggt cttaagaaag ctcgtaaagc atcacaattt
    53161 agtaaacgtt aattcgaaag aattactata cttatacaga gcacctttcg gggtgttctt
    53221 tttttatact ttcttactaa attggtgcaa ttgacacagt tgttgcgact ttagtcgctt
    53281 acaaatgtgg ctgcaacctg acaaggtcag ttgcctcaaa acgttaatca atacgattat
    53341 atcaatgttt caaagcactc aaaagtttac cttattttta tagtaaggtg aaataagaat
    53401 aggacaaacc gaggataatc aaatcgaatt ctaacaatgt tttagaagta gaggtgtact
    53461 attctagttt caatctact
//
LOCUS       DAVKEV010000006        53362 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVKEV010000006 DAVKEV010000000
VERSION     DAVKEV010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53362
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.006"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..202)
                     /locus_tag="VWZ68_000362"
     CDS             complement(<1..202)
                     /locus_tag="VWZ68_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HEU9371453.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTF"
     gene            complement(215..964)
                     /locus_tag="VWZ68_000363"
     CDS             complement(215..964)
                     /locus_tag="VWZ68_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEU9371454.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            complement(976..1404)
                     /locus_tag="VWZ68_000364"
     CDS             complement(976..1404)
                     /locus_tag="VWZ68_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371455.1"
                     /translation="MSEIVEMSKKISNLNDKKEFHKKNCELRFQDSVLDNINSVPGTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            complement(1665..3281)
                     /locus_tag="VWZ68_000365"
     CDS             complement(1665..3281)
                     /locus_tag="VWZ68_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9371456.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTSQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            complement(3291..4244)
                     /locus_tag="VWZ68_000366"
     CDS             complement(3291..4244)
                     /locus_tag="VWZ68_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9371457.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLFFKYMLLYYFGFFYCIYDNYVQLKFRK"
     gene            complement(4237..5441)
                     /locus_tag="VWZ68_000367"
                     /pseudo
     CDS             complement(4237..5441)
                     /locus_tag="VWZ68_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            5678..6004
                     /locus_tag="VWZ68_000368"
     CDS             5678..6004
                     /locus_tag="VWZ68_000368"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371458.1"
                     /translation="MEKVDRDKLKIYIETHPDAYLTEIAAEFNCPPTTIHYALKAMGY
                     SLKKSRTYCEQDPEKVNRFLKELNHLSYLTPIYIYETGVKTYFYLEYDRALSRQLVSL
                     EEDIII"
     gene            6205..6285
                     /locus_tag="VWZ68_000369"
     CDS             6205..6285
                     /locus_tag="VWZ68_000369"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9371459.1"
                     /translation="MLPLPTYSPEYNPIEKIWAYIKNISE"
     gene            6677..7983
                     /locus_tag="VWZ68_000370"
                     /pseudo
     CDS             6677..7983
                     /locus_tag="VWZ68_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(8023..9033)
                     /gene="tsaD"
                     /locus_tag="VWZ68_000371"
     CDS             complement(8023..9033)
                     /gene="tsaD"
                     /locus_tag="VWZ68_000371"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEU9371460.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHELPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFANLDLNAKPSLAFDT
                     ME"
     gene            complement(9023..9460)
                     /gene="rimI"
                     /locus_tag="VWZ68_000372"
     CDS             complement(9023..9460)
                     /gene="rimI"
                     /locus_tag="VWZ68_000372"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEU9371461.1"
                     /translation="MIEIKRIQQHPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            complement(9457..10140)
                     /gene="tsaB"
                     /locus_tag="VWZ68_000373"
     CDS             complement(9457..10140)
                     /gene="tsaB"
                     /locus_tag="VWZ68_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEU9371462.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            10318..10503
                     /gene="cibA"
                     /locus_tag="VWZ68_000374"
     CDS             10318..10503
                     /gene="cibA"
                     /locus_tag="VWZ68_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEU9371463.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            10505..10657
                     /gene="cibB"
                     /locus_tag="VWZ68_000375"
     CDS             10505..10657
                     /gene="cibB"
                     /locus_tag="VWZ68_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEU9371464.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(10980..11195)
                     /locus_tag="VWZ68_000376"
     CDS             complement(10980..11195)
                     /locus_tag="VWZ68_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371465.1"
                     /translation="MYNLFAFAIGVRLLAFIVFVACVYGGNLLFAKLERRQTKFLWKM
                     TFVTLYSLFLLLVTYVVWFVFYFELNA"
     gene            11475..11708
                     /locus_tag="VWZ68_000377"
     CDS             11475..11708
                     /locus_tag="VWZ68_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEU9371466.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            11710..13389
                     /locus_tag="VWZ68_000378"
     CDS             11710..13389
                     /locus_tag="VWZ68_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU9371467.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(13487..13564)
                     /locus_tag="VWZ68_000379"
                     /pseudo
     CDS             complement(13487..13564)
                     /locus_tag="VWZ68_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(13768..15681)
                     /gene="mnmG"
                     /locus_tag="VWZ68_000380"
     CDS             complement(13768..15681)
                     /gene="mnmG"
                     /locus_tag="VWZ68_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEU9371468.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(15691..16146)
                     /locus_tag="VWZ68_000381"
     CDS             complement(15691..16146)
                     /locus_tag="VWZ68_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9371469.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNEKTEDAVVREVKEELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            complement(16287..17408)
                     /gene="mnmA"
                     /locus_tag="VWZ68_000382"
     CDS             complement(16287..17408)
                     /gene="mnmA"
                     /locus_tag="VWZ68_000382"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEU9371470.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLATAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTNLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            complement(17808..19853)
                     /gene="pspA"
                     /locus_tag="VWZ68_000383"
     CDS             complement(17808..19853)
                     /gene="pspA"
                     /locus_tag="VWZ68_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HEU9371471.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTLVRAEEAPVANQSKAEK
                     DYDAAVKKSEAAKKDYETAKKKAEDAQKKYDEDQKKTEEKAELVRKADEKRQKANLAV
                     QEAYVKFQEAQREFNESPSRKKSDAKKKLDDASAHIEEVKLKQKEADANFNKEQAKVI
                     PEASDLAVTKQKAEEAKKEAEVAKEKYDKAVQEVEVEKNKILEQDAENEKKIDVLQNK
                     VADLEKGIAPYQNKVAELNKEIARLQSDLKDAEENNVEDYIKEGLEQAIADKKAELAT
                     TQQNIDKTQKDLEDAELELEKVLATLDPEGKTQDELDKEAAEDANIEALQNKVADLEN
                     KVAELDKEVTRLQSDLKDAEENNVEDYVKEGLDKALTDKKVELNNTQKALDTAQKALD
                     TALNELGPDGDEEETPAPAPKPEQPAEQPKPAPAPQPAPAPKPEKTDDQQAEEDYARR
                     SEEEYNRLPQQQPPKAEKPAPAPKPEQPVPAPKTGWKQENGMWYFYNTDGSMATGWLQ
                     NNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMATGW
                     LQYNDSWYYLNANGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMAT
                     GWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYKVNANGEWV"
     gene            complement(20140..20643)
                     /locus_tag="VWZ68_000384"
     CDS             complement(20140..20643)
                     /locus_tag="VWZ68_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371472.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     GLHKITRDYASQTKPAIQDGVFILEDFRNILLYNDVIERISLYEFIGDIFYSKITSCC
                     IVAKDLSKNTMKLDVIFFEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTD
                     VKEMKWL"
     gene            complement(21775..22503)
                     /locus_tag="VWZ68_000385"
     CDS             complement(21775..22503)
                     /locus_tag="VWZ68_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371473.1"
                     /translation="MNNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKAKEYELFKNSK"
     gene            complement(22500..22853)
                     /locus_tag="VWZ68_000386"
     CDS             complement(22500..22853)
                     /locus_tag="VWZ68_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU9371474.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKSDCQGICAALAMSPGT
                     FIALAGSAVLTKKLINYIKFGGLGGWLIGAAAGVLATAAGKIAYCIGYGALNRGCDIS
                     GNPYPWDGFISATVR"
     gene            complement(22909..23811)
                     /locus_tag="VWZ68_000387"
     CDS             complement(22909..23811)
                     /locus_tag="VWZ68_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371475.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            complement(24019..24393)
                     /locus_tag="VWZ68_000388"
     CDS             complement(24019..24393)
                     /locus_tag="VWZ68_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEU9371476.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            complement(24770..25747)
                     /locus_tag="VWZ68_000389"
     CDS             complement(24770..25747)
                     /locus_tag="VWZ68_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371477.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKSLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            complement(26061..27119)
                     /locus_tag="VWZ68_000390"
     CDS             complement(26061..27119)
                     /locus_tag="VWZ68_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371478.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEDGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            complement(28001..28213)
                     /locus_tag="VWZ68_000391"
     CDS             complement(28001..28213)
                     /locus_tag="VWZ68_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371479.1"
                     /translation="MLIVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            complement(28221..28592)
                     /locus_tag="VWZ68_000392"
     CDS             complement(28221..28592)
                     /locus_tag="VWZ68_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HEU9371480.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WIFTNIIDGWDGRRDNQLRIG"
     gene            29350..29670
                     /locus_tag="VWZ68_000393"
     CDS             29350..29670
                     /locus_tag="VWZ68_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU9371481.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSILFHLKKEVEIYYQ
                     AKER"
     gene            complement(29959..30429)
                     /locus_tag="VWZ68_000394"
     CDS             complement(29959..30429)
                     /locus_tag="VWZ68_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEU9371482.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQIGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(30395..31201)
                     /locus_tag="VWZ68_000395"
     CDS             complement(30395..31201)
                     /locus_tag="VWZ68_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU9371483.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(31417..32058)
                     /locus_tag="VWZ68_000396"
     CDS             complement(31417..32058)
                     /locus_tag="VWZ68_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9371484.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(32055..34163)
                     /locus_tag="VWZ68_000397"
     CDS             complement(32055..34163)
                     /locus_tag="VWZ68_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9371485.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(34215..34502)
                     /locus_tag="VWZ68_000398"
     CDS             complement(34215..34502)
                     /locus_tag="VWZ68_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU9371486.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            34927..35247
                     /locus_tag="VWZ68_000399"
     CDS             34927..35247
                     /locus_tag="VWZ68_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU9371487.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVPIGICTDNAKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            complement(35300..35872)
                     /locus_tag="VWZ68_000400"
     CDS             complement(35300..35872)
                     /locus_tag="VWZ68_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU9371488.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            36114..36785
                     /gene="sdaAB"
                     /locus_tag="VWZ68_000401"
     CDS             36114..36785
                     /gene="sdaAB"
                     /locus_tag="VWZ68_000401"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEU9371489.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            36794..37666
                     /gene="sdaAA"
                     /locus_tag="VWZ68_000402"
     CDS             36794..37666
                     /gene="sdaAA"
                     /locus_tag="VWZ68_000402"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEU9371490.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            37688..38320
                     /locus_tag="VWZ68_000403"
     CDS             37688..38320
                     /locus_tag="VWZ68_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU9371491.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            38370..38447
                     /locus_tag="VWZ68_000404"
                     /pseudo
     CDS             38370..38447
                     /locus_tag="VWZ68_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(38713..40563)
                     /locus_tag="VWZ68_000405"
     CDS             complement(38713..40563)
                     /locus_tag="VWZ68_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU9371492.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(40605..41762)
                     /locus_tag="VWZ68_000406"
     CDS             complement(40605..41762)
                     /locus_tag="VWZ68_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9371493.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKEDIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINQNML"
     gene            41820..42986
                     /locus_tag="VWZ68_000407"
     CDS             41820..42986
                     /locus_tag="VWZ68_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEU9371494.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            43125..43451
                     /locus_tag="VWZ68_000408"
     CDS             43125..43451
                     /locus_tag="VWZ68_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU9371495.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            43438..44031
                     /locus_tag="VWZ68_000409"
     CDS             43438..44031
                     /locus_tag="VWZ68_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEU9371496.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYATRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            44024..44935
                     /locus_tag="VWZ68_000410"
     CDS             44024..44935
                     /locus_tag="VWZ68_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEU9371497.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            44998..46062
                     /locus_tag="VWZ68_000411"
     CDS             44998..46062
                     /locus_tag="VWZ68_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371498.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVPQAEVELESQQEEKIEAPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(46240..47100)
                     /locus_tag="VWZ68_000412"
     CDS             complement(46240..47100)
                     /locus_tag="VWZ68_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEU9371499.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFERVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(47375..48361)
                     /locus_tag="VWZ68_000413"
     CDS             complement(47375..48361)
                     /locus_tag="VWZ68_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEU9371500.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEEREQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(48633..50108)
                     /locus_tag="VWZ68_000414"
     CDS             complement(48633..50108)
                     /locus_tag="VWZ68_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEU9371501.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(50318..51241)
                     /locus_tag="VWZ68_000415"
     CDS             complement(50318..51241)
                     /locus_tag="VWZ68_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9371502.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(51255..52184)
                     /locus_tag="VWZ68_000416"
     CDS             complement(51255..52184)
                     /locus_tag="VWZ68_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9371503.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGTLWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(52503..52723)
                     /locus_tag="VWZ68_000417"
                     /pseudo
     CDS             complement(52503..52723)
                     /locus_tag="VWZ68_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(52677..52937)
                     /locus_tag="VWZ68_000418"
     CDS             complement(52677..52937)
                     /locus_tag="VWZ68_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371504.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
BASE COUNT        16495 a        11236 c         8941 g        16690 t
ORIGIN      
        1 aaaatgtatc aaaaaaagta atatttaagt tattctcgca aaaaaacttc ataagctctt
       61 catttttaga tggaagaatg ccctttttta aattatttat ttttacagaa tctatatcat
      121 atgcaacaac tttatattta gatgcaaata gtaacgcgta ggccagccca acatgcccca
      181 aaccaattac tgctatattc ataaaactac ttccttattt cttaatccaa aatctaatag
      241 aataagctgc cccattcctt aaatacaact ctttaatatt gtttaaaagt ttttcaactg
      301 atttccagat tatcaaaatc tgagatttat agcacaatat tgatgatatt ctatcaatat
      361 aatgtttttc atcaagttcc tcttgataca tttttaattc tttagttttt cccatataac
      421 taaccatact actatcactt acatatggga agtcctcata atatattact ttataacgca
      481 taaattcaag cgcccttcca atactattca caaaaacatg atcaacatgg tcaccaagtg
      541 aaagcggaca atatacgaca catttatcgt ctaaatgcat taacagctct tttatgatat
      601 cattctttaa tgtgtcctca ttttttaatt cactatagat atgacggtat agaaaattgc
      661 catttctatc tttcctatag agacattcat agtacgataa gtgtctaaaa tcacattgta
      721 gacgttcaca agctaacctg tcttctttct tcctttcttc aatcggatat ttcccaaggt
      781 tacacaactt atgaaattgc ttagcagagg gctgtagctg ttggctcaaa gggtaaccag
      841 aaaatatagt aataacaagt acaatttctc cttctgaagt taattttgaa atataatcac
      901 cacaggaaaa aattgcgtca tctaaatgtg gagataaaaa gatatactta gtattgttac
      961 tcataaccat tccctctaca atttatctaa aaactcacta agtgtctgat taaattccac
     1021 atcatcaaaa aaattcacct tattcttaat aatgaatatt tcgttaaata aacatatata
     1081 taaatatttc aatatccttt caatatcatc ctctaaattc tcctcaatat tttgtatcag
     1141 cccatttaca atcttattaa aaaagataag ctctttatct ctaaaattaa atattttcat
     1201 acaactgttg tatcgaaaaa tatataaaat aatttttact aatgtttgaa tatttaaaca
     1261 actaaataaa tgagttgtac ccgggacact atttatgtta tcaagaacac tatcttgaaa
     1321 cctcaactca cagttctttt tgtgaaattc ttttttatcg tttagatttg atattttttt
     1381 agacatttca acaatctcag acattttata tggatatcta ggatgaatgc caaaactatg
     1441 caaaatgaac tgcaccccaa aagttagaca gaataaatct aacttttggg gtgcagttca
     1501 taagattggg atattttttt ttagctagaa ctagtagaaa tatatagtca aataacagat
     1561 accttaaggg tttctcatct acataaaaaa atgatacttt tttctcttca gtaattacct
     1621 cataagcttc acaatagaat ctcatgtttc cctcccctat attcttaaat aaaatccttt
     1681 ggaaattgat atatcttagt aaaatattgt ttaagttccg gatgcggagc atgggtaaca
     1741 ataatgacag tcaaatcctc tctatctaat atcttacgtt caatcgctaa cgaagttctc
     1801 ctatcgatag cagaagttcc ctcgtcaatt aatactattt tcttatttct aattaggcct
     1861 ctagctaaag taattttttg tttctgccct cctgacagta atctcccatc atcaccaaca
     1921 taataatcta aaatgttatt aggaaaatct tttacactca aaccaacttg ttctaaagac
     1981 tgtagtattt cttcatcagt ataattttct tccaataaaa tattatctct aatcgtacct
     2041 tcaaacaaat aagctttttg atctacatat agaacattcg aaaccatatt taaataggag
     2101 gtttttttta tatcatcccc gcagaatcgc aattctccac tataatctct caaaaagcca
     2161 ttcaataatt ttaataatgt agatttcccg cttccacttt cacctaaaat taaatacttt
     2221 tcattacgtt gaaaacaaaa atttaagttt tttaatattt ctttatctcc atacttatag
     2281 caaatatttt ttgcttcata taacggaaaa tctctattca cctcatttgg ttcgatatca
     2341 ttcattttat ttgactcaat tggattaatt gaatacaatt ttaaaaaaat aggcttcgta
     2401 ccaataatag aggataattg acctcctaat tcacctagcg ctgtaaaaat aacacctgtt
     2461 agtgctccta ttgcttcaat agtaccaatt ttcactattc cttttattgc aagatagcct
     2521 gttaaaaaaa cgagagatat ctgaaaaaaa atattgagaa agaagctaat agcgcctgct
     2581 aacgtttcta cagttgtctt tctttgtata accatcttta ataaaattcc tgcttcttta
     2641 attttcttag gcaatacata taaaagattc aaggacgcta acacatcaaa tccattcaat
     2701 atagtctcac tagattttaa aaaagcttca ttttggctag ttaaatttag actaacttct
     2761 cgcattttcg atgcaaagat ttttggtaca agtagcataa tcattaatga aaacaaggtg
     2821 gctacagtca atgaccaatg atagtgatta agagtcacaa ctgcaaatat agtaccagaa
     2881 attcctttta ttactaaaaa aagttgttta aaagcctgat catttaaagt ctgaacatca
     2941 ttatttagcc acgaaagata tgttcctgat gatttactat gaaattcttg ataggtagag
     3001 ttagagatgt ctgtggcaac tctatttcga atctctagat taaactcttg gatcacttca
     3061 acctgataat ttttcactac ccagtcaagg aatattatcc cacaccagac aatcatttgg
     3121 tagattgaca atttcaaaaa ccgctctaaa ttcatcgcaa ttaattcatt caacaccaga
     3181 gcattaatag ttgctgcata aattagcaat aattgaccag caacaataaa tatcgttaat
     3241 aaactaaatt tttttatatt tgattttata atagtataca caatagtttc tcactttcta
     3301 aattttaatt gaacatagtt gtcatatata caatagaaaa aaccaaaata atataataac
     3361 atgtatttaa aaaaaagaaa ttcgttaaaa attttttctt ctcttgcctt cttgattact
     3421 tttaaagcct tgcatttgtc tcctattaat agtaaccgct ttatgtttaa agaataatat
     3481 ttctttgtaa ccaatattct ctcgttgaaa ctcaataaat taaaatattt cctacagtaa
     3541 ttataatatt cttcatctgc attaattgtt ttttgtgtca ctccagtgat accgttttct
     3601 ttactgtgag cgtagtaatt caccaagaat tctcgcacta tatcaatttg gtatccttga
     3661 gcaagtagtt ttaataaaac aacaccgtcc tgatgtgaat ctattttctc aaaaccatta
     3721 attaattcta gcacctcttt tttacacaac caaaatgacg tacctgctat attgtgaacc
     3781 atttgaacaa acaagggatt tccaacaaaa tcggtcttct cctcttctcg tgtaccattt
     3841 ggataaatta ttattccata actataaact aaagctaaat tcttcattct actcttttta
     3901 aaacaagcca tcaactttaa aattcgatct ggcatatatt catcatcatc gtctaaaaat
     3961 gatatatact tacctctaga attttttata cctatgtttc tggcattagt tgcacctaaa
     4021 tcttcattac ttaaaattaa cttaattcta tgatttgtat agccaaattg atggataatt
     4081 ttatttctta aatttacatt actataatta tcatcaataa ttataacttc gatattttta
     4141 taactttgat gtaaacaact tttcacagct ctaatcagag attcatacct attatgtgtt
     4201 ggtattataa tacttactaa ttcttgatct atattcctat ccatgactac tcttctctaa
     4261 taattcatca tatactctca tggtttctac aaacattttt tgcacagaaa aatgttttct
     4321 tatttttgat ttactattct cacctatata tttcaaatac tcagaatcat tgagtaaaaa
     4381 attagcacaa gcacacactc cctcaacatc ttccttctca aataaaaatc catcaaccct
     4441 atgttcaata atttcactta acccgccaac attactagct aaaaccggag ttccttgtga
     4501 cattgactct aaaacacaca taggtattcc ttctgtatca gaaggaatat acaataaatc
     4561 cgatatttgg taaactatag tagctggata gatttcacca agtaacctga aattatctct
     4621 acatttcaaa tggcaaattt tttctttcaa agcagcccac atactaccat ttccagccat
     4681 aataaaaatc acatcttctc tgactaaaaa taatttttct gcaaattcaa ggaatctatc
     4741 cggccttttt tctggatcca accttccaat ataacaaatg atttttttgt tatttggaat
     4801 acaaaattct tttttaaagt cttgaacacc tactacatct aaatcgctat ttgatacatt
     4861 aattccgtta tttattgcaa ttatcttctt attttttatt atactctcca atcttttttc
     4921 atagtttcag atacacaaat aaaagcatct cccatagaat atgtccaaaa atcaaaataa
     4981 gtcaagaatt tcttttttaa gttatattca acccatccat ggcatgttat cactgtctta
     5041 acctttccaa atccattctt gtcaagtttt tttaacatat ataaaaaata attagttgag
     5101 tagccatgac agtgtataag ttggattttt aataatttta aaatattttt aacgtgtaag
     5161 gcagtttcaa aattatttga acattgagta caatcaacat aggcaatatc taaattttta
     5221 taatcatcaa taacctttga atctctagat acgattatca aaataggata tagagacatc
     5281 cttctgatct gctttttaca aagtccaatt atatgcggat ctatacctcc acaatgtcca
     5341 ttattatacc taactataat atgagccgaa aacactatat ccttaatgtc tccatatcca
     5401 tcagggatat taatatttat ttttccacaa ctatattgca ttgtaaccat ctccttaaac
     5461 gacgcattat gatatttgat agagaaattt ttatgaataa ctcaataatt ttatagtaaa
     5521 tcatgcttat atctcaaaga tacctatttt ctcttgtctc gaccttctcc aaagaattgc
     5581 tataatacta ttacaaatac atctgcacta cacttcaaat tttagcactg tataaaaacg
     5641 tttcaataca ctaacttcaa gaaaacttcc actattaatt gaaaaagttg atagagataa
     5701 attaaagatc tatattgaaa ctcatcccga tgcttatttg actgaaatag ctgctgaatt
     5761 caactgtcct ccaacaacta ttcattacgc tctaaaggct atgggatata gtctaaaaaa
     5821 gagccgtacc tactgcgaac aagacccaga aaaagtaaat cggttcctta aagaattgaa
     5881 tcacttaagc tacctgactc ctatttatat ttatgagaca ggggttaaga cctattttta
     5941 tctcgaatat gatcgagcct tgagcaggca gttagtctct ctggaagaag atataattat
     6001 ttgaattaag atcgagacaa cgcacaccag agattgcgat actgttatag aagtactaat
     6061 gccctttttt gtttcaatat actatggctc cttcgaagct tgcttccaaa aattcttact
     6121 acctacttta gatacaccat cccttatcat tatggacaat gcaaggtttc acagaatgaa
     6181 catgtgtaag gagcagggca tagactgtta ccacttccta cctattcacc cgagtataat
     6241 cccattgaga aaatatgggc ttacatcaaa aacatctcag aataatattg tcaaattacg
     6301 atgcttttct tgaggcactt ttgtcctatt cttgtttcag ccgactatac tccgttattg
     6361 ggcagctacg gaacagtcga tgggacgatg gggggacata aaaaaatcct ccagttttgt
     6421 tttttataac agtatactgg agaattgaca atctcggtag atacctcgtt atagcgcggt
     6481 tacttattag gcagttacaa aacaactgtg aacagaaaac attccagagt cagacaagac
     6541 tttggaatgc tttggctcta taatttctgt agtgggtaat cccaccccag gaattatagg
     6601 gtcgtttctt gtagaaaaaa agccccatat gacctataat gaaaagcgtc taaccaactc
     6661 attagaaagg gttcatatgg aacaacttaa gaataccaca gatttgctcg gattggaaga
     6721 caaaaatatc aaaatcttgt ctgttctgaa ataccaaacc catctagtcg ttcaggcaaa
     6781 gttggattcc cccgctcctc cttgtcctca ttgtcaaggg aagatgatca aatacgactt
     6841 ccagaaagcc tctaaaattc cgcttctcga ctgtcagggt ttacccacgg tactgcatct
     6901 caaaaagcgc cgctttcagt gcaagaattg ccttaaggtg gtcgtttctc aaacatccat
     6961 tgtcaagaaa aattgccaga tttccaacat ggtgagacaa aaaatcgctc agctcctcct
     7021 tgaaaagcag tctatgactg agattgccca cagattggcg gtctcaactt ccaccgtcat
     7081 ccgaaaactg agggaattta agtttgaaac cgattggacc aagttgccaa aagttatgag
     7141 ttgggatgag tatagcttca aaaagagcaa aatgagcttc attgcccaag attttgagtc
     7201 caaatccatc ctcgcaattt tagacgggcg aactcatgcg gtgattcgaa accatttcca
     7261 acgctatcag agagaggttc gggagctggt cgaggtcatc accatggaca tgtacagccc
     7321 ttattatcgg ctcgctaagc aactctttcc aaaggcgaag attgttcttg accgcttcca
     7381 cattgtccaa catctgagcc gagctatgaa ccgagtacga atccaaatca tgaaccaatt
     7441 tgaccgaaaa tccttggagt atcgggcgct caagcgcttt tggaaccctc gctttttcgt
     7501 ttctaggctc gggctaaatc agtccactgg actgatttac tacaccagga tagcttcaag
     7561 ctctgtcaga aacgattcta tcagcccacg tttcgaatgc acttaaccca tcgggaagta
     7621 cgagataagc tgctttctta ctctgaggga ttacaggttt actacgaact ctatcaactc
     7681 ctgctctttc attttcaaga gaagaatgcc gaccatttct ttggattgat tgagcaagaa
     7741 ctgccaacgg ttcatccgct ttttcaaacg gtcttttgga cttttttaag ggatagagat
     7801 aagattatca acgcacttaa gctgccttat tccaacgcta aacttgaagc gaccaataat
     7861 ttgattaagg ttatcaagcg caaagccttt ggtttccgga actttaacaa ttttaaaaaa
     7921 cggattttga tgactttgaa catcaaaaaa gagagtacga atttcgtact ctccagattg
     7981 tagcttttcg cctacccact acacttgaca aagagccact ctttattcca tggtatcaaa
     8041 ggcaagactt ggtttggcat tgaggtccaa gtttgcaaag ttttctttgt tccactcgct
     8101 gacgctggca taggcaatca tacctgcatt gtctccgcag agtcgcagag gggggatgat
     8161 aaccttgaca tctgtgattt cggctgctag gcgttctctg agacctttat tggctgccac
     8221 accacctgcc acaactaggg ttttaacagg atatttctcc aaagccttct tggtttttgc
     8281 catgagaatg tccataactg ctgcttggaa ggaagcacac aaatcttctg tagacaggct
     8341 ttctcccttt tgctcggcat tgtgatgaag attgataaag gcagatttca aacctgagaa
     8401 ggagaactcc agattatctt ccttaatcat ggcacggggg aaatcataaa tatcctgccc
     8461 ctgatgagcc agctcgtcaa tctcacgacc tgcaggatag gtcaagccca tgacacgacc
     8521 gaccttgtca taagcctccc caactgcatc gtctcgtgtc tccccaacaa tcttgtaatc
     8581 gccagcctca gaaacataga ccaactctgt gtgcccacca ctgactaaaa gggctagcaa
     8641 gggaaactcc aaaggctcca cactctgagc tgccatgagg tgcccagcca tgtgattaac
     8701 aggaatcagt ggaagttcgt gagcccaagc aaaggccttg gcagctgaca aaccaactag
     8761 caaggctccg accaagcctg gtccgtaggt aaccgcaaca gctgtcacgt cctcttcggt
     8821 aatccctgct tctgccaatg cctcctcgat acaggctgta atgacctcga catggtgacg
     8881 actggctact tcgggcacta cgccaccaaa acgtttgtga ctctcaattt gactagcaat
     8941 gacattggac aagagctcat cgtcgttttt caagacggcg acactggtct catcacagga
     9001 tgtctcaaat gctaaaatat atctatcctt catctatttc tctcttcatg ataatggcgt
     9061 cctcgactgg gtcatggtag taggcctttc gctcagcgat aactgccatc ttttctttct
     9121 tgtaaaatgc ttgcgctcgt tgatttgact gtctgacttc gaggaaaatt tccttgtctg
     9181 tcggcaattg agcaaacaag gctgacgcaa ttccctgacc ctgataagct cctttgacag
     9241 cgatttgcag gacttctgct tcaaaaagat tctcctgcac agctagaaat ccaatcactt
     9301 ctgccccatc ataagccaat gcataccaag tctggtcttg ggacagatct gcttggattt
     9361 gctccagagt ccaaggactg actaggtaaa cagctgccat aacagcgtag atggcttgag
     9421 ctaggtcagg atgttgttga attcgcttga tttctatcat aggcgtttaa tgtaggactc
     9481 accagactcg gtgtgattct tgagccagtt ttcctcagct tcgacacgct tgaggtagtt
     9541 cggcacaaaa tcatgcaagg agtctgcttc cttgtcccaa gctaaaagag caagattggc
     9601 tgcattgggc aatgtttctt tgtaatcagt ccttggcaag tgtttttgaa tctgctcaac
     9661 aaaggggcca acttctccga caaaggttac ctgactagta cccttgactt tttctagcac
     9721 ctcttcaaaa gataggtgcg cttctgccat gacaggtttg gcattttcat aaaatcctgc
     9781 ataaacatta ttgcgacgcg catccatcaa ggggacaaac aaaccttctt gttggtgggg
     9841 caccagagcc aagagactcg acataccaac caactcgatg ttcagggtgt aagctaaggt
     9901 cttagcagtt gctaccgcaa ttcgcaagcc tgtatagcta cccggccctt cagctaccac
     9961 gattcggtcc aaatccttgg gtgtccaatc caaacttgcc atcaaaaaat cgatggcagg
    10021 cataagagta atactgtgat ttttcttaat attaatcgtc gtctcggcaa gaacctgctt
    10081 atcctctaaa atagccagag aaagagcctt gctggacgta tcaaaagcta atactttcat
    10141 aacacattcc tatctttttg tctgcttact attatactac aaaagctggc acatgggaat
    10201 tttctttgcc cccagacaag agtgccctca cttaactaaa aataatttaa aaaaatgctc
    10261 acttttcctt ttcttttccg aatataaaag tgaacaagaa aaaaggagga aagttcaatg
    10321 acaaattttg acattcttga caatcaattt ttatccttat ctgaaaatga attatcagat
    10381 attgatggcg gtctcgctcc cttggttatc tttggagtag cagtatcttg gaaggctatt
    10441 gcaggtggaa cagcacttat aggttctggt ttggcagctg gttatttttt aggaggagat
    10501 taatatgatg aaagatttga acaattatcg tgaaatttct aataaggaat tgcaagaaat
    10561 caagggtggc tttggtgtcg gtgttggtat cgctttattt atggcaggtt ataccattgg
    10621 aaaagacctt cgtaaaaagt ttggtaagtc atgctagata agaaacacat ttttagaagg
    10681 ataaatttta ttgtcttcat ctcttacagt ttgctcagca ttctcaatga tttgaacatt
    10741 actaccatcc ctttaccatt cgatttatct gtttgtattg ttttattttt atgcttcaac
    10801 tctatttttg atcagaacaa tgactcccat aaaaataata agctttgaaa attccattgt
    10861 catgtcatgt tagaaaaatg caaagaccac ctcatcttga tagatggggt ggaattttcg
    10921 tgtcgtaaat ctactatctc tacatcccca aacaaaaaac cccagcataa gcagggcatc
    10981 taagcattta attcaaagta aaatacaaac caaacgacat aggtcacgag gaggagaaaa
    11041 agcgagtaga gagtcacaaa ggtcattttc cacaagaact tggtttgtcg tcgttccagt
    11101 ttggcaaata gaagatttcc tccataaacg caagcaacaa aaacgataaa agctagcaaa
    11161 cgaactccga tagcaaaagc aaataagtta tacatagggc aacctccttg acttaaaatc
    11221 tatatggaat tatgacaagc aataaatttc acttccgtta tcaacataat acattttctt
    11281 tatttttgca aacgcttacc aaagaaatcg tcccctaact ttctcgtttc cgtcttttac
    11341 taatttttca ttttgtggta taattgaaat aattgtaacg aatcaaggtc aatctagaca
    11401 caaaatggaa tgaaatcaag caaatctctg ctaaaagttt ggaataagct gacctgtaaa
    11461 tagaaaggaa ctatatgatt tacaaagttt tttatcaaga aacaaaagaa cgtagcccac
    11521 gccgtgaaac aacacgcgcg ctttacctag acatcgatgc cagctcagaa cttgagggcc
    11581 gtatcactgc tcgccaactt gtcgaagaaa atcgcccaga gtacaatatc gaatatatcg
    11641 aactcttgtc tgacaaattg ctcgattacg aaaaagaaac tggcgccttc gaaattacgg
    11701 agttctaata tggcctacac tcttaaacct gaagaagtcg gcgtttttgc catcggtggt
    11761 ctaggagaaa tcgggaaaaa cacttacgga attgaatacc aagacgagat tatcatcgtc
    11821 gatgctggga ttaaattccc agaagatgac ttgcttggta tcgactatgt cattcctgac
    11881 tactcttaca tcgtggacaa tatcgaccgc gtcaaggctg ttttaatcac acacggacac
    11941 gaggaccaca ttggtgggat tccgttccta ctcaagcaag caaatgtccc tatctacgct
    12001 ggaccgcttg ccttggcttt gatccgtggg aaactcgaag aacacggcct cttgcgcaac
    12061 gccaaacttt acgaaatcaa ccacaacacc gagttgacct ttaaaaatct caaggcaact
    12121 ttctttagaa cgactcactc tattccagag cctttgggga ttgtcattca tactcctcaa
    12181 gggaaaatcg tctgtacggg tgactttaag ttcgacttta ctccagttgg agaacctgcg
    12241 gacttgcatc gtatggctgc gcttggtgaa gaaggcgtgc tctgtctcct gtctgactcg
    12301 acaaatgcgg aagtaccaac ctttaccaac tctgaaaaag tcgttggtca gtccattatg
    12361 aagattatcc aaggtattga aggacgtatc atctttgcat cctttgcctc aaatatcttc
    12421 cgtctccagc aggcaacaga agctgctgtt aagactggac gcaagattgc ggtctttggt
    12481 cgttctatgg aaaaggccat tgtcaacgga atcgatcttg gctacatcaa agctcctaag
    12541 ggaaccttta tcgagccaaa tgaaatcaaa gattatcctg caggagaagt tcttatcctc
    12601 tgtacaggta gtcagggtga gcctatggca gccctctctc gtatcgccaa cggaacccac
    12661 cgtcaagtac aattacaacc aggtgatacc gttatcttct cttctagtcc catccctgga
    12721 aacactacta gcgtcaacaa gctgattaac atcatttctg aagctggtgt cgaagttatc
    12781 cacggtaaag taaacaatat ccatacatct ggacacggtg gtcagcaaga gcaaaaactc
    12841 atgctctgct tgattaagcc aaaatacttc atgcctgtcc acggtgaata ccgcatgcaa
    12901 aaagtccacg ctggactagc agtggatact ggtgttgaga aggacaatat ctttatcatg
    12961 agcaatggcg atgtgcttgc ccttactgct gactcagctc gtatcgcagg tcatttcaac
    13021 gcccaagata tctatgtcga tggaaatcgt atcggtgaaa ttggcgcagc tgtcctcaaa
    13081 gatcgtcgcg atctatctga agacggtgtc gttctggcag tcgcaactgt tgacttcaaa
    13141 tcgcagatga ttctatctgg tccagacatc ctcagccgag gctttgtcta catgagagag
    13201 tctggcgact tgattcgcca aagccagcgt atcctcttca atgccattcg tatcgcactg
    13261 aaaaataagg atgctagcgt gcaatctgtc aatggtgcca ttgtcaacgc tattcgcccc
    13321 ttcctctatg aaaataccga acgtgaaccg atcatcatcc cgatgatcct cacaccagat
    13381 gaagaataat actcttcaaa ccacgtcagc ttcgccttgc cgtatatatg ttactgactt
    13441 cgtcagttct atccacaacc tcaaaactgt gttttgagct gacttcgtca gttctatcca
    13501 caacctcaaa gcagtgcttt gagcaaccta cggctagctt cctagtttgc tctttgattt
    13561 tcattgagta caaatcaaca aaacagcccc gtcttcggag ctgtttttct ctatgctttc
    13621 ttttgagatt aaaactcaat gaaaatcaga ctagaaggct aagcgaaagc ataacttgag
    13681 ttagctccca tagttcgggg aactatggga ggttggagat gaatcaaagc caagctttga
    13741 actcattcgt aagaagccga cgacgtatca ttttgatttt tgaagagttt tagaaatact
    13801 acgattttta ccttccagat acaccatcaa aatagaaata tctgctgggt ttactcccga
    13861 aatacggctg gcttggccga tggtttctgg attgatgagt ttgaacttct gacgagcttc
    13921 cgtcgcaata gaatcgatgt catcccagtc gatattggct ggaatgcgtt tttcttccat
    13981 acgtttcatc ttggcaacct gatccatggc tttggaaata tagccttcgt acttgatttc
    14041 tgtttcaatc aattcgataa tcttgtcatc caagtcttct gcagctggtc cgatgaaggc
    14101 caccacatct tggtaagaaa cttctggacg gcgaaggaat tctttggctg tcaccgcatc
    14161 tgtcaacggc ttgaagccca tttcctcaac cttagcattg gtttccttga ctggcttgag
    14221 tttgatactg tctaggcgtt tcatctcatt atcaaattga tttttcttga tttcaaaacg
    14281 agcccagcgt tcatcatcca caaggccaat ctcgcgtccc atctcagtca agcgcatatc
    14341 agcattgtca tgacgaagaa tgagacggta ttcagcacga cttgtcaaga gacggtaggg
    14401 ttcaatggtt cccttggtca ccaagtcgtc gatcatcacc ccgatataac cgtcactgcg
    14461 cttcaaaatc aactcaggct tgccttggat tttcagagcc gcattgatac ccgcgataat
    14521 cccttggcca gcagcttctt cataacctga tgttccattt gtctgaccag cagtgaagag
    14581 acctgagatt ttcttggttt ccagagtcgc acgcaactga tgaggcaaga ccatatcata
    14641 ctcaatagca taacctgtcc gcatcatctc tgcattttcc aaacctttga tggaatgaac
    14701 caagtcacgc tggacatcct caggcagact ggttgaaagt ccttgaacat agacttcctc
    14761 agtattgcgc ccttctggct caaggaagag ttggtgacgt tccttgtccg caaagcgcac
    14821 aatcttgtcc tcaatcgatg gacagtaacg aggccccact cccttgacca cacctgtaaa
    14881 cataggcgca cggtggaggt tgttttggat aatctcatga ctggtaccat tggtgtaggt
    14941 caaccagcat ggcacttggt ccttgacata atcctcatca cgtgaagtgt atgagaagtg
    15001 attaggtgct tcatctcctg gttggatttc tgtcacatcg taattgatag aagaagcctt
    15061 gacacgtgga ggggttcctg tcttgaaacg accgatttcg aggcccagtt ccttgagatt
    15121 gtcagctagg ttaatagaag ccaagctgtg gttaggacct gatgagtact tgaggtctcc
    15181 gatgataatt tccccacgga gagcagtccc tgtcgtcaca ataacagcct tagcagcata
    15241 ttcttgatgg gtggctgtac gcacaccgac aaccttgcca tcttccacca aaatctcatc
    15301 aatcatggtt tgacgaaggg tcagattttc ttggttttca accgtcttgc gcatctcctt
    15361 agagtaaagt tccttgtcag cctgcgcacg aagggcacgg acagctggcc ccttccctgt
    15421 gttgagcatc ttcatctgga tgtaagtctt gtcaatggtt ttggccatct cgccaccgag
    15481 ggcatcgact tcacgcacga caatcccctt ggcagaacca ccgatagagg gattacaagg
    15541 catgaaagcc agcatttcaa tattgatggt cgcaagcagg accttacagc ccatacggct
    15601 agcggccaag gaagcctcaa ccccagcgtg tcccgcacca attacaataa tatcgtattc
    15661 ttcagtaaaa tgataagtca tgtttctctc ctattcctca agatgaatgt gtcttagttg
    15721 gccttcccaa tctggtaggg ctgtttttaa aaaggctgga actagctgga tatcctcaag
    15781 cttatccaag tcaatccact cacagggctg ccttttctca tcttcctgca tggtcaacgg
    15841 ggcatcttca agcaaatcca ccagataatg aaactcgata ttgtgatagg aaacgccgtc
    15901 cacttcaaaa cgattttcaa ccacaaaagc tagctgccca gcttgagctt taacacctag
    15961 ttcttccttc acttcacgga ctaccgcgtc ttccgttttt tcgttaactt gaatcgcacc
    16021 gccgatagtg taatacttgc ccttgtcttt ggtgactaga agcttgtgat tttggacaat
    16081 caaggctgtc gcccgaacac caaaaaccgt attgtctact tttgtccgaa agtcttgttg
    16141 agtcattctt gtcctttccc ttaaacgaca caaaaacagt caaaactaca aagaagtgca
    16201 ggacaaaaaa gcctgcaaca tccatgagct ttgaccatca tttctattgc tgttattatt
    16261 gtagcaaatt gagaaaattt gtcaatctaa atgtactgac aaacttgtcc atcgcggtaa
    16321 gcattgtcaa tcaaaccgcc acctagacac tcttcgccat cgtaaaagac aactgcctgt
    16381 cctggtgtaa tcgcgcgttg tggttccgca aagataactt ctgccttgtc tcctttgaca
    16441 tggacggtca ccttagagtc aggctgacgg taacggaatt tagccgtaca ttctagcgta
    16501 aactcttctg gcatttcacg agtaaagtgg acttgactgg cttctaggtt agttgacatg
    16561 agcgaatcat ggtagaatcc ttgtcctaca tagagaatat tcttgcttag atcttttccg
    16621 acaacgaacc aaggggcatt gtcaccgccg tgttgcccac cgataccgag tccgccacgc
    16681 tgaccgattg tatagtacat aagacctgca tgctcgccca tatcgcgacc atccacagtc
    16741 atcatgcgac caggctgagc tggcaggtag ttgctgagga agtttttaaa gttcttttct
    16801 ccgataaaac aaatccctgt cgaatctttc ttcttagcag tcgccaggcc tgcttcttct
    16861 gctagtctgc gtacttcagg cttttccaaa tgtcccaaag ggaacatggt tttttggagt
    16921 tgttcttgcg aaagttggct gaggaaatag gtctggtcct tgccattgtc cacgccacga
    16981 agcatgtgaa cagtgccgtc ctcatcacgc gccactcgag cataatgccc agtcgctaca
    17041 tagtctgccc ccaaggtcat ggcatagtcc aaaaaggcct tgaacttgat ttccttgttg
    17101 cacataacgt ccggatttgg cgtgcgccct gcacggtatt ccgctaggaa atactcaaaa
    17161 acgcggtccc agtactcttt ttcaaaattg acagagtagt agggaatgcc aatctggtct
    17221 gccaccgcaa ccacatcctt gtaatcttcg gtcgccgtac aaacgccgtt ttcatctgtg
    17281 tcatcccagt tcttcatgaa gataccgatc acatcgtagc cctgctcctt gagcaaaaga
    17341 gccgtcaccg acgaatcaac accaccactc atccccacga caacacgtgt tttagagtta
    17401 tcactcatgg taagtctcca tctattcgtt tattcacgat tgaaggtcgt gtgtgcttca
    17461 cgattgaagg tcgcttgagc agtattcatt ataacacgct tggttagaga agacaaggaa
    17521 gagcttaaaa attgtttttt aaaacttata gtcaatatac agatcatgtg aatgacgtga
    17581 gtataccctc ttcttatctt cattcaaata actataataa ataaaacaac ccattttctc
    17641 taatctattt ttcaagttag agaaaaggag tcgttttttt aatgacactt cctgaaatca
    17701 taagataggt acctaaagaa tacgaacata aatctattca atcgaacctt atctttgttt
    17761 caaaattaaa atgtcaaatg ttcttaacat gatttaattt aatcggctta aacccattca
    17821 ccattggcat tgactttata gccatctaca gttgtgttga ctgcaagggc acctaaacca
    17881 ttgacatagt accatttatc tgatactttg aaccattggc ttgctttcat agcacctgat
    17941 gcttcaagat agtaccaggt atctccatct ttcacccaac ctgttgccat tgaaccgtta
    18001 gcgttgaggt agtaccatga accgttgact ttagcccaac ctgtagccat agcaccgtta
    18061 gcgttgaggt agtaccatga accgttgtat tggagccatc ctgtagccat agcgccgtta
    18121 gcgtttaggt aataccatga atcgttgtat tggagccaac ctgtagccat agcaccatta
    18181 gcgttgaggt agtaccatga accgttgact ttagcccaac ctgtagccat agcgccgtta
    18241 gcgtttaggt aataccatga accattgtat tggagccaac ctgtagccat agcgccattg
    18301 ctgttgaggt aataccatga accgttgttt tggagccaac ctgtagccat tgaaccatca
    18361 gtattgtaga agtaccacat accgttttct tgtttccaac ctgtttttgg tgcaggaact
    18421 ggttgctctg gttttggtgc tggagctggt ttttctgctt ttggcggttg ctgttggggc
    18481 aagcggttat attcttcttc tgatctacga gcatagtctt cttcagcttg ttgatcatct
    18541 gttttttctg gttttggtgc tggagctggt tgaggagccg gcgctggttt tggttgttca
    18601 gctggttgct ctggttttgg tgctggagct ggagtttctt cttcatcacc gtcaggacct
    18661 aattcattaa gagcagtatc taatgctttt tgagcagtat ctaatgcttt ttgagtatta
    18721 tttaattcaa cttttttatc agtaagagct ttatctaagc cttctttaac gtagtcttct
    18781 acattgtttt cttcagcatc ttttaaatcg ctttgaagtc tagtaacttc tttatctaat
    18841 tcagcaacct tgttttctag atcagcaact ttgttttgaa gagcttcaat attagcatct
    18901 tctgcagctt ctttatctaa ttcatcttga gttttacctt cagggtctaa tgtagctaat
    18961 actttttcaa gttctaattc agcatcctct aaatcttttt gagttttatc tatgttttgt
    19021 tgagttgtag ctaattcagc ttttttatca gcgatagctt gctctaaacc ttctttaata
    19081 tagtcttcta cattattttc ttcagcatct tttaaatcgc tttgaagtct agcaatttct
    19141 ttatttaatt cagcgacttt gttttgataa ggagcaattc ctttttctaa atcagcgact
    19201 ttgttttgaa gtacgtcaat tttcttttcg ttttcagcat cttgttcaag tattttattt
    19261 ttctctactt ctacctcttg aactgcctta tcatattttt ccttagctac ttctgcttct
    19321 tttttagctt cttccgcttt ttgtttagta acagctaagt cacttgcttc gggaattact
    19381 tttgcttgtt ccttattaaa attcgcatcc gcctcttttt gttttaattt tacctcttca
    19441 atatgagctg atgcatcatc taatttcttt ttagcatcag atttttttct gcttggactt
    19501 tcgttaaatt ctctttgtgc ttcttggaat tttacatatg cttcttgaac tgccaaattc
    19561 gctttttgac gtttttcatc cgcttttcga acaagctctg ctttctcctc agttttcttc
    19621 tgatcctcat catatttctt ctgagcgtct tctgctttct ttttagccgt ttcgtaatct
    19681 ttcttagcag cttcagattt tttcactgct gcatcatagt ctttctcagc tttagactgg
    19741 ttagctacgg gagcttcttc tgctctcacc aaagtaggct gagacgtaac aaaaccagcc
    19801 cctaagatag cgacgctggc tagacttgtt aaaatcattt ttttcttatt catctaaatt
    19861 tacctctttt ctgatagtca tttttagact atacttatat taagtatact ccccccgtaa
    19921 atatttgtca aatgttttat attacatttt tattacaaat ttctatatca taagcttcta
    19981 ctccaaaaag ataaagacac tacttttgcc cttttcgatt ctctttttaa acatagcatc
    20041 atcttccttc attcctataa aaacatttcc gatgagagag cttgtttttt taatttcgtt
    20101 aaacaacaaa aaacgcaagc ttaagcctgc ggacaatctt tatagccatt tcatttcttt
    20161 cacatctgtt ttacgaactt tagcatattt cttagcgctt gtaaaatgta gggtaactgg
    20221 tttaaatact ccgcttttgt ctcttcgtaa acctaaaact gcggatcttt tatttttatc
    20281 ctcaaaaaat atgacgtcca atttcatagt atttttagat aaatccttag ctacgatgca
    20341 acaacttgtt attttagaat agaaaatatc acctataaac tcatataaag atatcctttc
    20401 gattacatca ttgtacaata ggatatttct aaaatcttct aaaataaaaa caccatcttg
    20461 aatagcaggt tttgtttgac tagcataatc tcgtgtgatt ttgtgtaagc caaataaatg
    20521 atgtaaatca gtcaagcaaa aattcacttt gaaagtctct aaatacttat aattcgttga
    20581 tacttgacat gtttttccat tgaatctttc ttgatagtcc aaaatacaat caagtaattt
    20641 caacgacaaa ctccatattt tctcaaaata aaaagcacgg ggcagttctc actactgccc
    20701 aaagtggttg attagagtcg gcttctctaa ctccctatgt tgtgcttatt aggcttatcg
    20761 caagggaaca gtttttagct ctgccaagcc acataatgtg cttactacta tgtgtccatg
    20821 tcaccatgaa ttgccgaacg gtttaacgag aaagtatagt agattgaaac aagatgtgaa
    20881 caaatcgatt aggaaagtca aattaatttc tagaaatatt ttaacagtca taacggacta
    20941 ttccagattc aatctactat attactttta ggtttatccc aactcaatta tgacattttt
    21001 ttcaaaagtc aatatatctc actcttttca acgacaagaa agaggctgat aatcgaccaa
    21061 cctctgtttt tagatacagt tcaagtccaa actattcttt atagaaaagt ccgataaatt
    21121 cgagcaatag ttaacatact tacaaatata actcccaaaa tagataacac tattttcaca
    21181 aaactcagtt ccgaacctat gacatatata tgaaaaagag gggctagtcc tacacatata
    21241 tacaataagt agccaacaag ttttatctca ccaattcctg caaaaaaatg tttcatgtga
    21301 cgattctcca tttactccat taaatcagtt ttattttaga ctatcataaa acaatcacct
    21361 cttcaataaa aaccatttgc gaaatactat tctgaagcat tgatagctca gatttctcag
    21421 aatagagctg tcctaactat cgagcagctc aaatacatat atatgagcaa ttctaagcct
    21481 agaattgcta taaaataaat gtttccaggc tattctaagt ctttgactgc ttaaaatttt
    21541 acattctgaa ggattctaaa gctagaacag ctcaaaatca cgagaactaa ggtattcgaa
    21601 acttcagagt aatacaatcc ccataggaat tctccattct tattaagcat gattaaaatg
    21661 taatcctaac aagtgatcct cgactgtgtt tgtagcactt agttacctag ataagactat
    21721 ttccctttat catatctgat tttaagccgt tctaagattt aacctatgtt tctattactt
    21781 gctattttta aataattcgt attcctttgc tttgataaat ggaactgaaa aattagaaaa
    21841 aagaagtaaa accgaaaaca aatagcctgc tttttgaatc actaaaagat atcctaaaaa
    21901 taagtaagct ataacatcca atgcgaaaag aaaaaatatt ctcctcttca ttaaagtact
    21961 tgtgtcaaat aatctgatga ataaaaattt tatcgtagta tctacacaaa tttttatcaa
    22021 aaagataaga gccaatacac gattatcaac tgtaccgtaa agaatagatg gaaatatagt
    22081 taatataaaa ctagaaatct ctaaatattt tatccaagga gattgagaca ccttgcttct
    22141 aaactgacta attttcttat attcgttagt caatttagta gcaaaatctt ccccaattaa
    22201 atgaaagatt gctaactcta ggataaaaac acttattaat acggtataag tcaaaaaact
    22261 ttctgggaaa aacttattga ttaaaatggg gaaactcatt aacagaatcg aatttatggc
    22321 tagacagata gatactattt tatttttcac agaatataga ggtagtgata ctattgagta
    22381 gataaaagct aaaaaaataa gcaaaaaata ctccgtgtca tttataatcg ccctgaatga
    22441 taaaaatata tacatccaac atacgataat atgtattttt cgaatcttat ctacattatt
    22501 catcttactg tcgcagatat gaatccatcc caaggataag ggttcccgct aatatcacaa
    22561 cctctattaa gagcaccata tccaatacag taagctattt ttcctgctgc tgtagccaat
    22621 acacctgctg ctgcaccaat aagccagcct ccaagacctc caaacttaat atagtttatt
    22681 agttttttag ttaaaactgc agatccagct aatgctataa aagttcctgg gctcatagct
    22741 aaagctgcac aaattccttg acaatcactc ttgcttaaat aagccccccc atcaagatac
    22801 atcatttctt cttcatcaat cacaacataa ttatttggta atacaagttc catttgtttt
    22861 ctcctcctta gttgaaattg tttcatttgt tttacaaata ggacgaactt aaactatctt
    22921 tttattactc agtaataatt tccgagattt cattttatga tactctctat tcatacagaa
    22981 atcaaaattt tgccttaacc aacttgtata atagaaaaaa tctaattgat tgattctgat
    23041 gaggtgtatc ctaattttat caaccttgtt ggaccagttg ttattgttac taatagaaat
    23101 ctcatacagc agtaactcga caagacctgt acacagaagg gtgttatgag aatcttcaat
    23161 tttactcaga atatcctcaa agagttcact atccgttaaa aaggtagatt gattcatcgc
    23221 atcatacagc tgaagagaca ttaagtcaga ataactgaga tctgattttt gtattttatc
    23281 ctttaacgta tttgtcaaat cactttcaaa cgaatcttct ttttcccatt tattttgatt
    23341 gaaaagaaat tccgtcttat taaaaacgag atgattgata tccattatag tccagaaaaa
    23401 tattgtagta agcatgatga ttgcaaaagg aatttttaaa ataaatacta ggataatagc
    23461 aatttcaaga ataaaactcc atataatcct agatcttaaa tcatcaggcg acaaactttt
    23521 acgatggaat gaaaaatagg gcgagaacct cacatttact ttcttcctgc ctataaaaat
    23581 aaaaggaaaa atcgtaataa gagcttcttt cttgtacaaa tctttcaatg cgtatagtat
    23641 gtctaaaact atttttgata aaatcaaact acagaaagca agactcatac taatcacaaa
    23701 atcaagggga gattctagat tcaatagtaa gttattcact aggacatgca actctagcca
    23761 caagacaaaa agagggagca ttaataaaaa aatgattagt ttacgtatca taattttaca
    23821 gtgtccttat cattttctta attttggata aattatcatt gctatgatta aaatcaaaaa
    23881 aacgacattc atccaaataa tcaatttttt tatttcttcg ctaacaaaat cataggctaa
    23941 aaaagttatg gatgatataa atagacatac aaaaaaaata ataacaaaaa ttttttccat
    24001 tttaataccc atatctagtt accacaaggc gtttaaattt gggtctctcc tatttacatc
    24061 attgttggcc cagattgttg taatagcatc gccaattgac atccaagctg caaatccatt
    24121 aatagcagac agtgcaaatc ctgccactct atttgcaact cgtaccccaa catatcttgc
    24181 agctgctcca gcaattgcgc ttgtaactcg ccgcaaacca taattacgaa tataatttct
    24241 aactagactg attgctcctc cacctaaaac accattaaaa gctatattaa tggctgttgc
    24301 aacaggccat ctcagaatag aaaatccccc atcaagatac atcatctctt cttgctcaag
    24361 agcaacataa ttatttggta atacgagttc catttatttt ctcctttttt attaagcata
    24421 gttaggatag tttcctaaca agtgatagac gactgtgttt ttatcactta gctacctata
    24481 taagatatcc tttctctacc ttatttgttt ttataggtta cctaaggttt aaaatcaatt
    24541 attgtttgaa acttaacagt tctaaaccac tagcaataaa taattgcgaa ctcactaata
    24601 ctatttcaaa atttattttt tttgacttag taacgcaatt ccaattagca atacacctaa
    24661 tataaataaa agtatttccc aaaatttatt ctcagtttta ataagtggaa taagatacat
    24721 actgactaat atgcaacttg cccctataat ggcaaatatt attctggttt tatctcctaa
    24781 ttgaaacatg tttgatcccc atatacactt caagcaaaag ttggatttct gaaatggcta
    24841 aagataaaga taagggttgc gagctattta aactatcatc aatattctgc tcgattaaaa
    24901 caaagtctgg tcttacctct aaaattttct ttaacattga ttcatattta tttttttcat
    24961 tataatgccg taaatataga tttaatttta taacatccaa cataccataa agtgatattg
    25021 gatgatttat ttttttaaat cgcttaactt ctaataaatc aatttgttca cgcacactct
    25081 ctgaaagata tggcttgatc aaactgatat aagataaagc cacgcatggc aactcagatt
    25141 ttgattgcaa tttccaaatt tcatgataat cctgaagatt aaactcacaa tccctcttag
    25201 attccagtat tgttagtact tttgatttta acagaaataa ttgttgattc tcaattctat
    25261 aaagtttttg tactaatgct atgataatag aaaatggaat aagaggcaaa agcaacgatt
    25321 tgtcatacac aaaagtaaag aaaaaatagt atgaaattag tgttgtaaag tacaagaagt
    25381 agtaaaattt aaacagattc ttagttgttt gactctcctt ataaaacact gctattcctg
    25441 gactaaatcc cattagttgg tgaaagagaa ttcgatagta tttcctagct cctataatga
    25501 tcacaaatat aaaataaaaa taaattggtc ttaatttaca aaagattgag gaaactagta
    25561 atagcaaagt atgtaagcat tgagacaaaa tatagaataa cggtatcgcc aatacaaagg
    25621 ttaagatggc atgagaggga gttcctaaga tgtccaattt tataaatact gggctgacac
    25681 aaaatatcgt gcttataagc agtaaaatta ttaaaattgt gtcaaaaaaa taacgcttat
    25741 ttttcattag tctactttcc attgttaaat aatactactg ctaacaccaa gccaacttag
    25801 cacattgcat cacctaatcc tgcgctactt gtccataatc ctttaatgtt tctactaaaa
    25861 ttattccaat ctcccccatc aagatagctt atttatccta gacaacgcct actgcaacag
    25921 tataaataag attcatcagc catcttttct ggcaatcata tgggtagact aatgatattt
    25981 ctagttactc aaaaatatct agctatacta gagttatttc taatccctag gacacttgtt
    26041 aatccaaatg taacaaattt tcacccctta ataggactct ttctggaaaa aatataaggt
    26101 ctatctttat aaaaaaatct atcatattgg gatggcacgc atctggaatt taaacaagct
    26161 ataaattcat ttataactac tatttgttta gaggcaacag catcttgtat accgtcctcg
    26221 aaagaaccat cttgtaattc cgaaatattt ttgtttaaat attgttttga caaatctctt
    26281 aatgcttcat tatcgtaaat gattcccaaa aatccaacct tatatagtaa ataatttaaa
    26341 cttacaaagt aattgaatcc catagtatat ttttctttat aaagcaaagg taaaacttta
    26401 taaaaaatat ctaagtcaac ctcactctga ttctgaagca agtaggagtc aagcaaattt
    26461 tcaaaaatag ctaacaatat gattggtgta aagtttttgt attcacatgt caagtattct
    26521 gagtatcgtg cagatgatat ttcttttata taactttttg aaagcaagat tttttcaaat
    26581 tcatcatcta ttattaatct tctatttcca atccaagcgg tattaccacc caaataagat
    26641 tgtgcaaata gcaatatgta agaaaatatg aacgtaaata ctgaaagagg tagaattcta
    26701 tgcgtaaaaa aatagacgat aatggtagcc aggagtaaag atatctctcg tgacaatcga
    26761 attcttttca gcatcttttt taacagtccg taaggttgtc cttggcaata ttcttgaact
    26821 aaattaatcg gaatgacatc tctcaccatt tctggaaagt agagtaagtt tataggttga
    26881 aatctccagc tcccatcata agtaaatgga tatagaacca aatacttaaa agattttttt
    26941 cttataaact taattatcac aatatgaatg actgttgcaa tgaagtatat taaatataaa
    27001 agtaaaaccg ccatcaatat acttacaaaa atccccttgg aatcaatcaa tggaaaataa
    27061 aatattgcaa ctagaagcga ataaagtccc gctaataaat atttctgatc atctttcatt
    27121 taaaacacca tattatttac taagaatgca tcaatacaat agagcaactc tgtaagtcaa
    27181 tatttgataa agcaaagctt taaacccttc cccagacgtt agcttttatt caacccacta
    27241 cagttgacaa ggagcccaaa ttattgataa aaactttagt catcatcgtc tctataaaaa
    27301 tattttctat acactcttga taataccaaa attaatgcca atatcatacc aagagctata
    27361 ataatagaat ttattagatt tattttagta tatccaatca ctagtccaat aattggacta
    27421 gcagacatgc ttagatataa taaaaataac aaaaaatgaa tttcaccaat tcctgcaaaa
    27481 aaatgtttca tagctatagt tttacgccca taaataccca tcaaatttac cgtctacgat
    27541 atctaaacca tatgcaatgg ctcctcctaa tgagaagact tcagcaacag tagccacaat
    27601 attaagagca ttagtaatag ttgccatact aactccacca atatatcttg ttatagcact
    27661 tagttaccta gataagatat cctttagctt gcttccaaaa tttaagtcta cacctataat
    27721 atgagttcat attagtactg ctaaatccta tctatagtaa tgtcaaacac ctaaataaag
    27781 tcatctctcc aattcattca agaaatgaat aaaggcaaaa aatctttaaa ataagaaaag
    27841 tgcatattat caggtgttca aaaatattga tgatatacgt tatatagata gaaagattta
    27901 ctcaatctca ctttcaaatt gagttttttc ccaacctcgt ttttaattta tatcttcaat
    27961 aaaatctaat gacctagttg atatgtcata tggaataata ttatttaatc tgtaattttt
    28021 ttaaaaaact taataataaa tttgctccac tgattgctat caatatttca attggtaaaa
    28081 aatagtaatt ccaaataaaa tgagaaatca gcaatgatag aaaaataaca atatcaattt
    28141 tcctgttgtt gacatactct gtaattttat gatacaggaa tgcaacaata actgaaatta
    28201 aaacaatcaa cataagatta ttaacctatt ctcaattgat tatcacgtcg cccatcccag
    28261 ccatcaataa tattggtaaa aatccaatca gctccagcac caattccagc agatgcaata
    28321 cttctaataa cagtatttgc aaaagcattt ccaatatgaa ttcctaatac tcctaaacct
    28381 ttaacaatcc cagctaccag tgcggagcgt aatccataag atgcaagaac tagttgaagg
    28441 cctccacctc ctgctgctgc taatgctgca tatgctgcac cagtaatggc tcctgtaatt
    28501 gcccacctgg gtatatatat agccccccca tcaaggtaca tcatctcttc ttcatcaatc
    28561 acaacataat tatttggtaa tacaagttcc atttattttc tcctttttta ttaagcatgc
    28621 ttaggatggt ttcctaacaa gtgatcgcag gctttgttta gttacctaaa ttagacttcc
    28681 ttcctttatc ttattttaaa tatttaaaac cagttactgc ttgaagctta acagtttact
    28741 taattcaaat aacagctaat cactgattcc ctgattttat caaatatact aataacaaca
    28801 attgtgatac gatcatcatt ataagaacaa catttaacga atcaaagttt ttccgagata
    28861 ataataaagc aacagcaagc agtattatta ctaaagattg aataactact attactctta
    28921 acattttatc ctccactaac aactcaagct cccttacatt atatcgacca gccccatgga
    28981 aagattatag ctagactaat caatgatata atacatacta gaatacaaaa tattttttta
    29041 ttcatacttt ttctcctatc tttattttct acctacatca tacctcttat taagctcatt
    29101 tcaaaattac gttaactttt ttcacgaaaa ggagacaatt atgcgttatg attatggata
    29161 gcgctttcaa atttttaaac tcctatccca tccttttatc tatattatga gcgaaaatat
    29221 aataactgtc aagtaactaa agtgaatttt ataaaaaaat tacaagccaa atttgtaaag
    29281 tttacactaa gccgctaggg caatcgtcta tcagaatgtc cgtttatttg tcaataatcc
    29341 gagaaaatct tgcaacgctt agaagtctat aaaaactatc aacatttata tgacttgcga
    29401 atagcaatcc tgctcaacct ttccacactc tatctataca atcaagataa aaacatgtgt
    29461 aagcaaatct gctacacttt actggaggac gccaagaata agaaaagcta cgataggctg
    29521 gctatctgct atgtccgtat tgggatttgt agggatgatg cgaaacttat ccaaaaaggg
    29581 ttctcccttc tggagctaac cgaggaaact tctatactgt ttcatctcaa aaaagaagta
    29641 gagatctatt accaagcgaa ggaaagataa aaaagccgag ggatttcctc gactctttac
    29701 atattatttg ttcgttagtt cttaatacca gctattgtta agccagaagt ttttagctct
    29761 gccaagccac atagtgtgtt tactactatg tgtccatgtc accatgaatc gccgaacgat
    29821 ttaacgagaa agtatgactt ttccgtttat cccaactcaa ttatgacatt tttttcaaaa
    29881 gtcaatatat ctcacttttt caacgacaag aaagaggctg ataatctacc aacctcttat
    29941 tctgaaccca tcactccatc actttttagc ttcattcgct ttcttagcga ctgcaatctg
    30001 gtattcgact tggtcattcc ccttaccggt acaaccatga gcaattgtag tcgctcctat
    30061 ctgatgcgct atttcaacca attttttaga aatcagaggg cggctcaagg cagataccaa
    30121 gggatacttt tgttcataat aggcatgtga ctgaagagcc actagcacat aatctgtagc
    30181 aaattcgtcc ttaacatcaa tgacataaga ttctactgcc ccaaccttaa gagccttatc
    30241 atggatgaaa tctaagtctt tcccttcacc cacatccata caaactgaaa caacatcata
    30301 gtctttcttt aaccaggtaa tagcaactga tgtgtccaaa ccgccagaat aggccaaaat
    30361 tactttttct ttactcatgt tcttttcctt ctttctattt ttcaatggat gctttaaagg
    30421 catcctcaat gagtttgtct aattccccag actccttcaa cttttgaatg gttttatcga
    30481 ctgcctcttt caattccttg ctatcttttt tcatggctac cgcgtaggaa tcatcttgct
    30541 ctttttcaaa attgaggtct gcgattgcta aatcaggatt attttccaca aatcccttgg
    30601 aaacaggttc ttcaaagata acggcatcca cttgtcctga ttttaaatct gtgattaaat
    30661 tcccattttt aggcagagat acgagggaag aattttgtag caaatctttc gccatcgtct
    30721 cttgaatcga acctttctgc gctccaacct ttttctgcgc caagtcgttt acagactgat
    30781 aagtagtcaa gtcagatttt ttgacaatga gtttattttt tgcagtatag tagggaatgg
    30841 aaaagtcaaa caccttgctc cgttcatctg tcttagaaac acctgatatg gcaaggtctg
    30901 cttttcctga ttgaacacta gccagtacat tatcaaaact catgggagat agttccaatt
    30961 cgacacctag ttctgttgcg atagccttgg ctaattcgat atctgaaccc acaatctgat
    31021 ttttcccatc aaccactttt tgatattcaa atggagcaaa atctggattg agggctacaa
    31081 ccaattttcc tttggacttg atggcttcaa ttccagccga ttgattgtta ctacaagcaa
    31141 atagtagggg gagcatcact aaaccaaaca tcgtcatcaa caccttcttc atcttattca
    31201 taacaaagcc ttctttatgt ttattctttt ttattgtata aataatactc ctatactcat
    31261 atactcatcc tttgtcaagc ctaaattgaa aaaattttca atttgaaaca aaaaaaaacc
    31321 tagaaatgct acataaaatg tcattcctag gcgtatttat gctatttttc tctggaaaac
    31381 atgagtattc agccagtcaa aaggagctga atgaactcat tttccctcgc ccaattcaat
    31441 gacacgatga cattgttggg ctacataagc atcgtgggtc acaataatga ctgttttccc
    31501 ttctcgattc atctctaaga gaaacttcaa gaccaaatct ctattttcag gatccagcga
    31561 acctgtaggt tcatcggcta aaatcagctg gctgggtttt aagatggctc tagcaactgc
    31621 aattcgttgt tgttcgcccc cagacaactc ggagaccctt tgatgcaaag tagctgacaa
    31681 acctactctc tctaaaatct cttccacctt tttgagcttg tctttcttag gcaatttcac
    31741 atatttcagc gccagcatga gattgtactc gaccgtttca tcatcaatca gggcaaaatt
    31801 ttgaaacaga taagagatat gttcacggat tattgtttgc gacttagcag aattaaccgc
    31861 tagatttgtc tgaccaaaaa tctcataccg tccgctataa tcaccatcta tcaaacccaa
    31921 taaatttaac aaggtcgact tcccactacc actcttacca acaatagcta ccaaatcccc
    31981 ctgatcaatc ctgagagata agttatccaa aatcactttt cccccaatgg ttttggtaat
    32041 atttttcaac tcaatcataa gatgccccct ttcaataact ctactagact tcttttctcc
    32101 atcctagaag ctaagcctag cacaaatagt atatccagac atgtaaaacc tgcaaacagt
    32161 agaagtggta agaacgcatg ggcaaagaaa atcaagacta gaagagggaa actatagccc
    32221 agcaagagca gaacgaggag aggacggtag cgatcgacca gtttccaccc cataaacttc
    32281 ttggtaatga tatccctgcg cttcaataag aaagttgtta ctagtaagaa gtaggaaatc
    32341 atcatgctaa ggagaccaaa caaagcaaag agtaggttaa aattccgaac agcatctcta
    32401 taagaatcca ctttctcttg ttgaatggct tgaatagatg aaaattttaa ataatttcca
    32461 tctgacaatt tctcaactaa ctctgtaatc tctttttgat gttgaaccgt attttcaatt
    32521 ttaatcggat tatttaagcc agttgttgac agggaggctt tctcatccca catcatatca
    32581 gaatcattga ccaagctaat aattggattg gagagatttt cctttcgctt atcactatat
    32641 gggaaaaatg accaatctcc ttcataatag gcaatctcga catccatctc ctctatcgtt
    32701 cgtttttgct gctcttcata cttcatcgaa tgaaaggcaa ttaacttccc caagagctga
    32761 tttttatctt cttcaccttt cgtacttgct ggcatcaaaa taactttttt aataccggta
    32821 tctggtagct tgaatccctt gctctttaga aaattgcgat tggcatagta aacatccacc
    32881 gtatctgtta actgatattg ctgaatctgt tctgattgga caaaattttt tacaggaaga
    32941 ctgctactct gcacatagcc cgcctgcgtt ttttctacca aatcctgata aaatcgatag
    33001 aaataatctg tagatttccc tgaccctgct agctcttctt gccacagatt atcattgagt
    33061 ttgaaggttt ctaaggtcag gtaattacct tgacttaccc actgttgctg ataagcaagt
    33121 tctttgtttt cttgttctaa acttctgccc accccaatca gtaaggccgt cagtaaaata
    33181 gttgtcccta ttttcatcac ataattgaag ataagaccaa atttgaaaga tgaaaaacct
    33241 ttcagcagag agctgattgt cattttttgg attaagaggt aagtcaacca actgataaag
    33301 agataaagct gcaacagcaa aaaatgagac aaccacagca taggaaacaa atcttttggc
    33361 ttataatcaa gcaagaaaaa cacgcctaga ttgatcacaa gagccccacc taggaggagg
    33421 taaaggttgc cttttacaac atcagctaaa acagccctat cttgaaaacc aagtaatttt
    33481 tgtaccccaa ctcttttcat ctccatcatc ggttgataca ctgtcactaa cacaagaagc
    33541 aaaatagcca agacaaaaac aatggcagat aaaagcaaat ctcgatttat gacttccact
    33601 gcacttttgt aggtcggctc tagcaaggta gcctggtcta tcttgaaaaa atcgctccat
    33661 ttctgtacaa tcctatcctt gtccatctct tgtgtagaag ttatcgtata gcgaccattt
    33721 aaactacgag atgtatcctt gatataggtt tgaaaagtca taagctgaat aggtttggct
    33781 tttagaaagg tcggaatcgt accaagttta ttggaaattt ctttattact atagactcct
    33841 tcaccatctg tggtaaaatc aagagaagaa atcccaaact cttggtaggg gaaggtatct
    33901 ttatcaaaaa caccagactt gaccacctca tcaccactgt ctgttttgat gatggagact
    33961 ttatactcct ttgatacatc ctcaaaaaat cgaagaacag acgctgcagg ttcgttaata
    34021 tctttcaaat acaaatccaa agaatctaca gtctttccca tttcttgaat ccgaaccact
    34081 tctcgtgtat agtttacatt aaaaacaaaa aaagtggtac acagaagcag gagtaacata
    34141 cagaaattac tgattttttt cataaaagtg cctccactac agttttccct ctccaaatag
    34201 gagagggaag aattttactc aaatccatag aaatattcca ttcctgttgg cggaatcttg
    34261 gtgagggaag ctctagccca tgcctcaggt tttgcataat ccttagaggt tctaccccca
    34321 tgtctaacag ttgctgtatg atatcgagta gaatgtaagt aatcagaata tccaaaagtt
    34381 cctgtccaac ctactccata gttccattga ccaccctcaa cccatactgc taaagcattt
    34441 gtagtagcaa gtataccaca taccattaaa gatgcaacac caattttaac taattttctc
    34501 atgatttatt tctcctatta tcgagagctg ttccgtaaaa acagctatag taatttatca
    34561 acaagtatcg tagtccattg gactcacctt ccttctatct catttcattt tttaacaacg
    34621 aacttactct taaccgggag aatggtgcgc ttctgtatca ggtccttgaa caaccagagt
    34681 agtattaagc acactctaac tattactcaa gaatcagtcc aataaacaat atggatagcg
    34741 ctttcaaatt tttaaactcc tatcccatcc ttttatctat ataataagcg aaaatataat
    34801 aactgtcaag taactgaagt gaattttata aaaaaattac aagccaaatt tgtaaagttt
    34861 acactaagcc gctagggcaa tcgtctatca gaatgtccgt ttatttgtca ataatccgag
    34921 aaaatcttgc aacgcttaga agtctataaa aactatcaac atttatatga cttgcgaata
    34981 gcaatcctgc taaacctttc cacactctat ctatacaatc aagataaaaa catgtgtaag
    35041 caaatctgct acactttact ggaggacgcc aagaataaga aaagctacga taggcttgct
    35101 atctgctatg tccctattgg gatttgtaca gataatgcta aacttatcca aaaaggtttc
    35161 tcacttctgg agctgaccga ggaaacttct atgctgtctc atctcaaaaa agaagtagag
    35221 acccattatc aaccaaagaa attataaaaa aagtcgaggg agctcctcga ccttttacat
    35281 attatttgtt cgttagttct taataccagc cattgttaag ccagaagttt ttagcagcag
    35341 tccatgaacc gtaacgtcct gcaacgtagg catctgctac acgttcttgg ttttcagctg
    35401 agtagtcacc gttcaggtat gaatctgtta attggtaacg tccgatataa cgtccatttg
    35461 tagctgtata gctaccacct gattcttttt gagcgatcca ttctttggct tctgcttcag
    35521 atccgcttac agttgaaaca actgtttcac ttactactgg agctgaaaca gtttcatctt
    35581 gagcggctgg tgccgcataa gtagctggcg ctggtgttgc aacaggcgct acagggccat
    35641 cgataaccaa ctcttgatca acataaatca aatgaatgtt atcaatgtgg ttgttttctg
    35701 ccaatttttc aactgttgtg ttgtgagttt cagcgatttc tgaaagtgta tcaccttctt
    35761 taacagtgta agttgatgat tcttgagcag atacaaatga tggagcaaat actgcaaaca
    35821 aggcagctac tcctgcaaga gttgctttaa tctttttagt tattgatttc atattcgaaa
    35881 attctccttc tttctatagt tctatcatac cctttaaata ttaccgtttc ttgacacttt
    35941 tatgtagaaa tattacaaaa ttatttttta tttccctaaa taaggtgttt tttgtcataa
    36001 aagatactat ttttatgcta tttgaggtat tagaaaggtt ttcatccaca attaaagcca
    36061 agcccctcat tctttgatat aatagagata agaattttta taaggggaaa ctgatgaaat
    36121 cacttcgttt tcaatctgtc tttgatatca tcggaccagt tatgattggc ccatctagta
    36181 gccataccgc tggtgctgtt cgtattggga agattgtctc ttccattttt gatgatactc
    36241 cgacagaagt tgaattccaa ctttttaact catttgccaa gacctatcgt ggtcacggaa
    36301 cagacctagc ccttgttgca ggtattttag gaatggatac agatgatcct gaaattccaa
    36361 atagtctgga aattgcccac aagcgtggta tcaagattgt ctggaccatt cagaaagaca
    36421 gcaatgcccc tcaccctaac accactaaaa ttactgttaa aaatgcccac aagaccatca
    36481 gcgtgactgg tatttctatc ggtggaggaa atattcaggt aaccgaactc aatggttttg
    36541 ccgtctctct caatatgaat acaccgacta tcatcatcgt tcatcaagat attccaggta
    36601 tgattgccct tgttacagag gcgctttccc gctatggtat caatatcgcc cagatgaatg
    36661 tcactcgtga aaaagctggt gaaaaagcca ttatgattat cgaagttgac agtcgcaact
    36721 gtgatgaggc tatcgaagaa attcgaaaaa tccctcatct ccacaatgtc aatttcttta
    36781 aataggagga agcatgtttt attctatcaa agaattggtc gagcaagcag atctagactt
    36841 tcaaggaaat gtcgcagaac tcatgattac aacagagttt gaattgaccg gtcgcgaacg
    36901 tgaagaagtc ttccttctca tggaacgcaa tctggaagtt atgaaagcct ctgtccaact
    36961 tggcctcaat gaaaataaat ctcgtagtgg cctgacaggt ggagatgctg ccaaattgga
    37021 tcactacatc gaaaacggaa aaactctgtc agattacacg attctctctg ctgcccgaaa
    37081 tgccatcgca gtcaatgaac acaatgccaa aatgggcttg gtctgtgcca ctccaaccgc
    37141 tggaagtgct ggctgtctgc catccgttct cactgctgct attgaaaaat tagacctcag
    37201 ccacgagcaa caattggatt tcctctttgc tgctggtgcc tttggactag tcatcgcaaa
    37261 caatgcctcc atctcaggtg ctgagggtgg gtgtcaagct gaagttggtt cagcctctgc
    37321 tatgagtgct gccgccttga ctctggctgc aggtggaaca ccttatcagg ccagtcaagc
    37381 tattgccttt gtcattaaaa atatgctagg cctcatctgt gaccctgttg caggtttggt
    37441 cgaagttccc tgtgtcaaac gtaatgccat gggagctagc tttgctttca tcgcagcaga
    37501 catggccttg gcaggtatcg aatctaaaat ccctgtggat gaagtgatcg atgccatgta
    37561 ccaagtagga gcaagcatgc caactgcctt tcgtgaaaca gctgaaggtg gactcgctac
    37621 cacccctact ggtcgtcgcc tccaaaaaga aattttcgga gaataagctt atcaaatagg
    37681 agaaaccatg acctctatca cagcgatttt tttcgatttg gatggaaccc tcgttgatag
    37741 ttctatcggg attcacaatg cctttaccta tacctttaaa gagctggggg tgcctagccc
    37801 tgatgccaaa actattcgtg gttttatggg accacctctc gaaagtagtt ttgcgacctg
    37861 cctgtccaaa gaccaaattt ctgaagccgt gcagatatat cgttcttact ataaggcaaa
    37921 aggcatctat gaagctcaac tctttcctca gattatagac ttgcttgagg agttatcgag
    37981 cagttatcca ctctacatca ccacgacaaa ggatacatct actgctcaag acatggcaaa
    38041 aaacttggaa atccatcatt tctttgatgg catttatggt tctagccctg aagcacccca
    38101 taaggcagat gtcattcacc aagccttgca gacacatcaa ctagcaccag aacaagccat
    38161 catcatcgga gataccaagt ttgatatgct gggagctcga gaaacaggta ttcagaaatt
    38221 ggccatcact tggggatttg gagagcaagc agatctacta aactatcaac ctgattatat
    38281 cgctcacaaa cccttagaag ttttggcgta ttttcaatag catagactgg gtaacaattc
    38341 catttcagaa gaaaatgaag taatactcaa tgaaaatcaa agagcaaact aggaaactag
    38401 ctgcgggctg ctcaaaacac tgttttgagg ttgcagatag aactgacgaa gtcagatcaa
    38461 aacactgttt taaggttgtg gatggaactg acgaagtcag atcaaaacac tgttttgagg
    38521 ttgcagatag aactgacgaa gtcagatcaa aacactgttt tgaggttgtg gatagaactg
    38581 acgaagtcag taaccatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa
    38641 gagtataagt ctctacataa taaaacgcat attaccaagg ttgtgtaact ggatactatg
    38701 cgtttttctt ttttattcaa tgtgggttgt ttgattagca aaggcgataa tagcttgctt
    38761 caactcatct ccactgagag tgcggaactc tccaatcttt tgattgatgg attctaaagg
    38821 catgacatta accttaccaa cgaaaatctt atccataact tgattatcaa cgagttcggt
    38881 tgataccaag agttcttcgt agagtttttc acctgggcgg attccaactt caacgattgg
    38941 aatttcactt tcagtgtggc cacttagaag caccatcttc ttggccaagt cataaatctt
    39001 gactggtttg cccatatcaa ggataaagac ttccccatct ttggcataag caccagcatg
    39061 gataaccaga cggctagctt ctggaatggt cataaagtaa cgggtcatgc ggaagtctgt
    39121 caccgttaca ggcccacctt cagcaatctg acgttcaaag actggaatga cactaccacg
    39181 gctaccaaga acattcccaa aacgaactgc acagtaggtt gattggctac gttggttaaa
    39241 gccagtgaca atcaactccg ccacgcgctt ggttgctccc ataacatttg gtggattgac
    39301 tgccttatct gtcgaaatca taaccatctt agacacttta gcttcatcaa cagccttagc
    39361 aacattgtaa gttccacgga tattgttttt gaaggcttct tttggattgc gctccatcat
    39421 aggaacatgc ttgtgggcag ccgcatgata aacaatagca ggtttgtact gctcaaagac
    39481 ttgcaacaaa cgatcatagt cttgaatgtc cgcaatcaca ggtacataat caatcccttg
    39541 gaacttacga atcaattcat gataaacaag gtagattgag ttttccccat gaccgagcaa
    39601 gacaatgcgt tcaggattga agcgactaac ttgacgacag atttcagaac cgattgaacc
    39661 tccagctcct gtgactaaga tggtcttacc tgtcagttct gcacccagac gcgattcgtc
    39721 aagacggatt tcctgacgac ccaaaaggtc cgtaatatca attttttgga agccagtacc
    39781 tgcttggtga aggccctgaa caacagtttc aaccttaggc atcttgtaac atttgacacc
    39841 cagcttatta cacatctgca agatacgctc atattctgac ggatccagcg acggaatcgc
    39901 aacgatgaca cgctcgattt gatggcgttt ggctaattca ggcagattgt cataagagcc
    39961 caaaacagga ataccaccaa gtttttgacc ctttttctta gaatccttat ccaaaatacc
    40021 gaccagttct aattcactgg ttggatgttg gtaactatcc ataaagagag ccccaccatc
    40081 accggcacca atcaagaagg ttcgacggtg ttctccatca ccactacctt ttttgcgtct
    40141 ggagtagatt aactgccaag taatccgtgg caataaaatc aagaaggtac tcaacaagat
    40201 aaagagaatg atgaaacgga tggagaagag tggcaagaag gcataacaga tactatatga
    40261 caagacactg ctagcagtca caccaaaaaa gattttcatg aaatccgtaa tcttgctgta
    40321 acgactaatg ctcgcgttca acccccaaaa accaatcatc aattgataga acaggaaggc
    40381 caaactcgta tagataatgt agtcaacagg tgctggatta atcagcccat aaaataaaat
    40441 ataagataca atgatggaaa ccaccatact gaaaatatca aatattcccc agaaaacctg
    40501 cttttgttgt ttatttaaaa tttccaccag atcaatcaca taatctgtta gttttttatt
    40561 catagaaatc tactcctcct taaaagagtt ttactatatt gttattatag catattttga
    40621 tttatttggc ttattttatc caaataaatt attgttctct tgtactcctt cttccattta
    40681 aatcctctaa ttaaacctac aatcgtccca aagccataag caaagtgaat ggaaaataaa
    40741 agaaagggca tcacaattag aaatccattt ttatgtttta ataaagtcag caaagtgagt
    40801 aatgacaaaa gtagaaaata ggcacctaat agtaaagtta tgaatacgaa tgtgatcggt
    40861 aacaatgcta gactaaacac aagactcaaa acaaataaac aaggaacata gtgaaataat
    40921 gataaacact taaactgaac atgacttgtc aagccaatcc acaaaccatt tgaatacttt
    40981 tgatgcagca ttttcttgaa tgttggtcga atatactgat aagatagaat acttgggcta
    41041 tagcggattt tataaccatg ttctcgaatt ctataatgaa tatcattatc ttcagttcgg
    41101 ccaagttgct catttactaa accaaccttc tggaaaacct ctcgtttata catcccatga
    41161 aaaatagaag aaacatatct atcctcggaa ctatttcgat aattggcaat gctactgcca
    41221 aacatatttt cctcaacaag atgcaaggtc tctgcccatt ttccttttcc ttcgacaatc
    41281 gtcggtctag gccccccaca gacaaattca ccttgttgaa taatagccac attgttcatt
    41341 acaaaactct cagtaacttt tgaatgagca tcaattttta aaataaggtc ccctacagaa
    41401 tgtttaactc ccaggttaaa accactagct tgatttttct taggattgtt atacaatcta
    41461 attgagttaa actctgtatc ttcctttata aattgctgaa tgatagctgt ggtcccatct
    41521 gtggacatag catttataaa tagaatttca atatcctctt taggataggt ttgatttttt
    41581 aagtcttcaa ttagaccagg cagatatttt tcttcattgt atgcactgat tacaatggat
    41641 acgagaagac tttcaacatt ttgagtcact actactctcc tgaatttttc cttccaccat
    41701 tctatcataa ttttcaagac tttcccattt ttatcttgaa agccagaaac cttacttgac
    41761 attatagtga aaaagcctta aaataagctg ttattaaaat cagctagaag aggtattata
    41821 tgaaaaagca atcactcttt tttgttccag gtattatcct gattggtgtt tccttgcgaa
    41881 ctccttttac tgttttaccc attattttgg gaaatatttc gcaaggtctg gaggtagaag
    41941 ttagttcgct tggtgtcttg accagcctgc ctctccttat gtttaccctc ttttcaccat
    42001 tttctaccca actggctcag aaaatcggct tggagcatct cttcacctac agcctcttct
    42061 tcttgaccat cggctcactt attcgactaa tcaatctgcc cctgctctat ctaggaacct
    42121 tgatggttgg ggcaagtgtc gcagtcatca atgtcctgct tcctagtctt atccaagcca
    42181 atcaaccaaa gaaaattggt tttctgacca ccttatatgt aacgtctatg gggattgcaa
    42241 cggctctggc ttcctatcta gctgtgccca ttacacaagc cagttcttgg aaaggactta
    42301 tccttctcct cacgttactc tgtctagcaa cttttttggt ctggctccca aatcaccgct
    42361 ataatcatag actagctcca caaaccaaac aaaaaagtca aataaaggtc atgcgtaata
    42421 aacaggtttg ggcaattatt atcttttcag gttttcaatc cttgatcttt tacaccgtca
    42481 tgacctggtt acctaccatg tctatccatg caggtctatc cagtcacgaa gctggcttgc
    42541 tgacttctat cttatctctg attagcattc ctttttcaat gaccatccca agcctgacaa
    42601 ccagtttatc tactcgcaac cgtcagctca tgctcactct ggtttcacta gctggtgtgg
    42661 tcggcatttc catgctcttt ttcccaatca ataatttcat ttactggctt gccatccatc
    42721 tcctcatcgg aaccgcaacc agtgccctct tcccttatct catggtcaac ttttcactca
    42781 agacaagcgc ccctgaaaag acagcccaat tgtccggcct atctcaaaca ggaggctata
    42841 tcctagcagc ctttgggcca accctctttg gttacagttt tgacctgttc cactcttggg
    42901 taccatctgt agctgccctc ttgctcatcg atatcctgat gactgtggcc ctctttacag
    42961 tggacagagc ggataagatc ctttaaactt ctagttttag ctagaagttt tttatatata
    43021 aaaattttac acatttctct tgacagggct ttcttttaga tgtacaatgt atgtgtagaa
    43081 aaattatata taaaaatctt acacattaga aaaggaggtt tcccatgtac tttccaacat
    43141 cctctgcctt gattgaattt ctcatcttgg ctgtactgga gcagggtgat tcttatggtt
    43201 atgagattag ccaaaccatt aagctgatcg ctaatatcaa agaatccaca ctctatccca
    43261 ttctcaaaaa attggaaggc aatagctttc tgacaaccta ctctagagag ttccaaggtc
    43321 gcatgcgcaa atactactcc ttgacaaacg gtggtataga gcagctcttg accctaaaag
    43381 atgaatgggc actctataca gacaccatca atggcatcat agaagggagt atccgccatg
    43441 acaagaactg aatacctgac tcagctagaa ctctatctca agaaactacc tgaagctgac
    43501 cgtatcgaag ccatggacta tttcagagag ctctttgacg atgctggagt cgaaggagaa
    43561 gaagaactca tcgctagttt gggaactccc aaagaagcgg cccacgaagt tctatccaat
    43621 cttctcgata aaaaaatcaa tgaagcaccc gctcaaaaaa ataaccgaca aattttacat
    43681 atcgccttgt tagccctcct tgcagcacct atcggcattc ctctgggaat cgccatcctc
    43741 gtgaccctgt tcgcaattct tgtagccgct ttgactgtca ttctggcttt ctttgcagtt
    43801 tccatactgg gtatcatcgg cggattccta tttttagttg aaagtttcac tgtcctcgcc
    43861 caagccaaat cagcctttat cttgattttt ggttctggtt tactggctat cggtgcttct
    43921 tcgctagttt tacttggcat ttcctatgca actcgcttct tcggtctact cattgttcgt
    43981 ctggtacaat ttgttcttaa aaaaggaaag agaggtaatc agcatgcgta aatggacaaa
    44041 aggatttctc atctttggtg tggtgactac cgttatcggc tttatcctgc tttttgtagg
    44101 tatccaatct gacgggatta agagcctact ttccatgtcc aaagaacctg tctatgatag
    44161 ccgtacggaa aagctaacct ttggcaagga agtcgaaaac ctagaaatta ctctccacca
    44221 acacacgctc accatcacag actctttcga tgatcaaatc cacatttctt accatccatc
    44281 tctttctgct caccatgatc ttatcaccaa tcagaacgat agaactctga gtctcactga
    44341 taagaaactg tctgaaactc cgtttctctc ttctggaatt ggtgggattc ttcatatcgc
    44401 aagtagctac tctagtcgtt ttgaagaagt tattctccga ctaccaaaag ggagaactct
    44461 aaaagggatc aacatctcag ccaatcgcgg acaaaccacc atcataaatg ctagccttga
    44521 aaatgcgacc ctcaatacaa acagctatat cctccgaatt gaaggaagtc gtatcaaaaa
    44581 cagtaaactc acaacgccca atatcgttaa tatctttgat acagttctta cagatagtca
    44641 gctagagtca acagagaatc acttccacgc tgaaaatatc caagtccatg gcaaggttga
    44701 actgactgcc aaagattatc tcagaatcat cctagaccag aaagaaagcc aacgaattaa
    44761 ctgggacatc tcaagcaact atggttctat cttccaattc acaagagaaa agcctgaatc
    44821 aagaggtacg gaattaagca acccttacaa aactgaaaaa accgatgtca aggatcaact
    44881 cattgcgaga tctgatgata atattgatct aatatccaca ccaagcagac gttgacaaaa
    44941 acgcttacat ttgctactat ggaaacatat ttatctaact aaaaaggagg ttctaccatg
    45001 aaacaagaat ggtttgaaag taatgatttt gtaaaaacaa caagcaagaa caagcctgaa
    45061 gagcaagctc aagaggttgc agacaaggct gaagaaacga tagccgatct cgatacacca
    45121 attgaaaaaa atactcagtt agaggaggaa gtccctcaag ctgaagtcga attggaaagc
    45181 cagcaagaag agaaaattga agctcctgaa gacagtgaag cgagaacaga aatagaagaa
    45241 aagaaggcat ctaattctac tgaagaagag ccagaccttt ctaaagaaac agaaaaagtc
    45301 actatagctg aagagagcca agaagctctt cctcagcaaa aagcaaccac gaaagagcca
    45361 cttcttatca gtaaatcttt agaaagtcct tatatccccg accaagctcc aaaatctagg
    45421 gataaatgga aagagcaagt gcttgatttt tggtcttggc tagtggaagc gatcaaatct
    45481 cctacaagta agttggaaac aagtatcaca cacagttaca cagcctttct cttgctcatt
    45541 ctgttttctg catcttcctt tttctttagt atctatcaca tcaaacatgc ttactatgga
    45601 catatagcaa gcattaacag tcgcttccct gagcagctag ctcctttaac tcttttttct
    45661 atcatctcta tcctagtagc gacaacactc ttcttctttt cattcctctt gggtagtttc
    45721 gttgtgagac gatttatcca ccaggaaaag gactggacgc tagacaaggt tctccaacaa
    45781 tatagtcaac tcttggcaat tccaatcttc ctcactgcta ttgctagttt ctttgctttc
    45841 tttgatagcc tacgatttac agccctcttg tgtgtgatta gcattggaat cattctgctt
    45901 gccagtctcc atatcattac aagaccaagt caagcaagtg aaaccgactc cttctatcaa
    45961 ttattcttgt ctgtccttgt gaacggagtt attatcctcc tcttctttgt agctgaagtg
    46021 gcactgattg gagattatct tcgtatcttg gcctttcttt aaacttcata ctcttcaaaa
    46081 atcaaattca aaccacgtca gcttcgcctt accgtactca agtacagcct gcggctagct
    46141 tcctagtttg ctctttgatt ttcattgagt agcaatcctg tcatccttgg caggattttt
    46201 tctatgtcaa aaaagcaagt cgattgacct gcttctgctt tacttttctt gtgctaatgt
    46261 tttaaaatct ttgtctaata tgggttgcac ttctatttga ttggcgtcta gttggtggta
    46321 aaaagatggg ggtaatacct ctaagaattt tgcatagtcc aagcgagcaa tggcttcata
    46381 gtcttctggt ttagagccat ctcctgtgat ttgaaccaag tcaatctccc actggacttc
    46441 cttatccacc aattgctcaa tataggctgc aggaacaaac ggttctctcg gtaaaactgt
    46501 cttgactcct tgagctagat ggtaaacgcc atgcactttt ccttctccat cctgatagaa
    46561 ggaaactctc tcaaagtagg catctgtctc ttgaaccgca cgcacacgcg cttcaaactg
    46621 agccaagcca tctgcctcta aaaagctttt caagttctca cgactaaaga aaataggatt
    46681 aaaaattcct tggcaaatcg taaaacgagc tacagggtct gctagatagg cttgaatact
    46741 tgcttggaaa taagcttcaa aatcaaaacc atctagccct tcaatatcag tccctgtata
    46801 agcaagcaaa gcatctaaaa atgacttgat aatctgccag tctgtctttg ttagtaggtc
    46861 aggaagatcg acacggtaag ccttttgacc atcagcataa ctgaccttaa agagaaattg
    46921 tgattgcccc actatcgcac actcgatata ttcgagacga ttaagaggct gacggagata
    46981 gactacatca tagctatgtg actccaaacc gtctagcaag gccaagatcg acttggcatt
    47041 caaaatctct tgttctccta aaatgctctg tttatttgga ataaaaaatg ttttcgccat
    47101 aactggactc ctttgaaatc gtttacatac agtatacctt atttttctga aagatacaaa
    47161 aacaaacttt atactcttcg aaaatctctt caaaccgcgt cagcttcgcc ttgccgtaga
    47221 tatatgtaac tgacttcgtc agtcttatct acaacctcaa agcagtgctt tgagcagcct
    47281 gcagctagct tcctagtttg ctctttgatt ttcattgagt attagatttt tgagtacaaa
    47341 gcatagaaaa acagccccta aggactgttt gatcttatac agtagctgcc tgatccaagc
    47401 tttcaccgat agcggctagg cgctcaatca cttcagcttg tgtcaattca ttttttgaaa
    47461 catagcggtt acgtgggtga acacggcact cgtgtgagca tccacgaagg tacttgtctt
    47521 cattttcttc tgatgtcaag atacgacggt tacagaaggg atttccacag ttgacataac
    47581 gttcacatgg tgttccatca aaccagtctt tccctacgat agttgggttg acatggttga
    47641 catcaacggc aatacgctcg tcaaagacgt acattttccc atcccaaagc tcaccttgaa
    47701 cttctgggtc tttaccgtaa gttgcgattc ctccgtgcaa ttggccgaca tctttgtagc
    47761 cttcacggac catccagcct gagaatttct cacagcgaac gccacctgta cagtaaacca
    47821 cgacacgctt gtccatgaat ttttccttgt tatcacggac ccattgtggt aactcacgga
    47881 agttgcgaat atctgggcga atagccccac ggaaatgtcc taggtcgtac tcataatcgt
    47941 tacgtgtgtc aaggacaacg gtatctttat caagaagcgc ttctttgaac tcttttggag
    48001 acaagtaagc acctgttgtt tcaagtgggt tgatgtcatt gtcaaagtcg ttgtcttcca
    48061 aaccaaggtg gacaatttct ttcttgtagc gaacaaacat cttcttgaag gcttgttctc
    48121 tttcttcgtc aatcttgaac cagagatctt ccatacctgg gaggctgtga acgtagtcca
    48181 tgtatttttg agttgtttca tagtcacctg aaactgttcc gttaattccc tcgtcagcga
    48241 ctaggatacg gcctttaagg ccgattgatt tacagaaagc caagtggtct gcagcaaatt
    48301 gctctgcatt ttcaattgga gtataaaggt agtaaagtaa gacacgaata tcttttgcca
    48361 taagatttgt tctcttttct attcttaaat tttctaaatt ttttatttat ccatactagt
    48421 atacctgctt gagaaaacga atgcaattta tttgactgga aattgtagag ggttctcgaa
    48481 atttcctgaa tggttaaaat aaggacaaga gaaaacatgg atatctatat ccttgtgcca
    48541 aaaaaaccac tgccctcccc agaccaacct gaggaaagca gtgattctta ttttaggagt
    48601 taggaatgaa tacacgaaat caatttagct gattattttt tgtttttcaa gaattcatcg
    48661 tattgttttt gcatttcgtt caatactttt tcgtaggcac cttcagattt caatttttcc
    48721 atcaattctg gaatagcttt atctgggtct acagtaccag tgttgatagc tgtatcaaat
    48781 tgttgcattg tgttagcaat agctgagatt tcagatttca cattgtcagt attgaagata
    48841 aatccaagcg ctggagattc tttagcttct gccaattctt tcttagaatt ttcgatttgt
    48901 tggtctgtaa cgttttcgtt gatgtaaagg atccagttgt taccagtgtt ccatccaccc
    48961 atgtgagtgt ttcctttgta gccatcaaga acgcgaacac ggttttcttt accttcaatt
    49021 ttttcccagt tcttgccttc tggaccgtaa acaagaccgt tcaagagttc tggattcgta
    49081 ttcaagaggt tcaagatttc cattgatttt tctttgttct tagagttgtt tgagatgaca
    49141 aagttagcaa cttgtgttgt ttggtttttc ttgatgaagt tagtaattgg tttgatttgg
    49201 atatctttgt tggcaacacg tgaaagcaag ctgttaccgt agtcagctgg tcctactgtt
    49261 tcttcacgaa cgaaccaagt atcttgttga aggtcaaagg aagtatcgct tgttgcgaca
    49321 tcttttggaa tgtagccagc ttcatagaat ttgtgaagag tcttcaagtg ttctttgaaa
    49381 cgaggcactt cgtaacggtt tacaacttta gtagtatcgc cttcaaggtc aataacgaat
    49441 ggaagcccgt ttgctactgg gtagtcaaaa ttatcagatg ggatgaaaac tttaccaata
    49501 gcaaatggta ctacgtctgg agctttttct ttgatttgtt tcaagactgg ctcaagagtt
    49561 tcgtaagaag taacacctga aatatcgata ccatatttgg caaggagagt tccgttgaag
    49621 gcaaagtttt gagatgatgc tacgttggct gcaactggta cagcataaat cttaccattt
    49681 acagtattac ccttgatata agctggatca agtgccttgt aaaggtcttt accttctttt
    49741 ttgtacaatt ctgtcaagtc agcataagca cctttttgag catttacaat atagttatct
    49801 gcaaaggcga tatcatagtt ttcaccagat gatgtgataa ctgacatttt cttaccatag
    49861 tcaccccagc caaggtattg gatatccaat ttggcaccaa ctttttcttc gatgattttg
    49921 ttggcatttg ctaacaattc atccaagtta tctggtttgt caccgatttg gtacattttg
    49981 ataacaggtt tgtcacctga atcagcagct tttttactgt tacctgtcaa gttgccacaa
    50041 gcagcaagac ctgcagccaa agcgactaca ctagcagatg caaaagcata ttttttccag
    50101 tttttcatga taaaaactcc tttttttatt tttaaactta taaacaatgt aatgatctta
    50161 tactcaatga aaatcaaaga gcaaactaga aaactagccg caggctgtac ttgagtacgg
    50221 caaggcgacg ttgacgcggt ttgaatttga ttttcgaaga gtattaactt cacacaaggg
    50281 aagttgggaa ctgagaaatg ttatttctca ataagcacta ttctttcaca ccaccgatag
    50341 tcaaaccttt tacaaagtag cgttggaaaa atggatacaa aatcgcgatt ggaagggttg
    50401 caaccacaac catggccata cgacctgttt ctttcggtag agcaactccc agttgaccag
    50461 tcaagccgac cgctttggca atgtagtcca tattttgttg gatttgcatg agcaaatatt
    50521 gcaatggata caagttgtca ctcttgatgt aaagaagggc gttgaaccag tcattccaga
    50581 aaccaagagc tgttaagagc gtgatggttg cgatacctgg tagtgacaat ggcaaacaga
    50641 tttggaagaa aatccgggct tcactggcac catcgatacg agccgattct agaatggctt
    50701 ctggaatggt cttcttgaag aaggaacgca tcaagatgat gttaaatggt gagagaagca
    50761 ttggaacaat caaggcccaa acagtatccc caagctgaag cacacgagtc accatgatat
    50821 aacctggtac caaaccagcg ttgaacaaca tactgagcag aacgaagatg gtaaagaatc
    50881 tgcgatactt aaaggttgtc cgtgaaatag cgtaggcata ggttgttgtg ataaagacat
    50941 ttgtcaatgt cccaactacg gttacaaaga cagagatgaa gagggcttgt aggattttat
    51001 ccttaaactg tgccaaaaac tcaaaaccgt ctaagccaaa ttgggatggg aagaagctat
    51061 agccgtattg gaggaggctt ttctcgtctg tcactgaaat aatgataacg aatacaaaag
    51121 gtaggataca agagagggca atcaaacccg aaatgatact gaagaagata tctgctttct
    51181 tactgaagga gtgaatgccg acattatcaa ttttttcttt tttaattttc ttttttgcca
    51241 tattctcctc ctttctagaa caaagctgag tttggatcga ctcgtcttgc aagcaagttt
    51301 gataggataa ccagaatcaa accaacaacg gattggtaaa gaccggctgc tgcagccata
    51361 ccgatatctg ctgtctgagt caaaccatta aagacatata cgtccaaaac gttggttaca
    51421 ttgtaaagct gaccagcatt gtgtgggatt tgatagaaga gaccaaagtc tgcgcggaag
    51481 atatttccga ctgcaaggat ggtcaataca gttacaagcg gagtcaactg aggaatggtt
    51541 acgttgcgaa tacgttgcca cttgctagct ccgtccactg tcgctgcttc gtagtaggtt
    51601 ggatcaattc ccatgatcgt cgcatagtac atgacactgc tatatccaaa gcctttccaa
    51661 atacctagga aaagtaggag atagggccag atgcccaggt cagcgtaaaa attgacttct
    51721 ttgagaccaa gactttccaa tagatgattg aacacccctt tatcaatatt taggaaggca
    51781 tctgtaaaga aactgatgat aacccaagac aagaagtaag ggaacaacat agaagtttgg
    51841 aaaatcttca ccattctctt agaacggagc tcgctgagga taatggcaat ccctacagat
    51901 acaactaaac ctagaaagat aaagccaaga ttgtagagga cagtatttcg tgtgataata
    51961 aaggcgtctc ttgaactaaa taagaatctg aaattatcga gtccgaccca tttactattt
    52021 atgatactat ctatgaaacc attactggtc atgtggtagt ctttgaaggc aaccacgttc
    52081 ccaaatactg gaatgtaaaa gaatagaatc aaccagagtg tccctggcaa aaccatcaag
    52141 agaaagatcc agttgtctct caatgttttt gaaaactttt tcataatttc ctcccttttt
    52201 attttgatat ccatctaaaa attctttttt agacttttga taacgattac attattagta
    52261 tactcctatt tgcaggttag gttaaactcc taattataga aaaaactcca caaattatgt
    52321 agcagattta aaactttatc accactatca aacaaatgtc ctaaatcaat tgtttatttt
    52381 atctctatta gcccagtgat ggcgtcactc tgttataagc atccaacaac ggggtatact
    52441 gaaaaatctc cagactaggg aactcagaga tagttcctaa tctggagatt tttaatatgt
    52501 tattaggcgt ttgctttcaa cttagcaata acctctttaa gattatcaat cacctctgct
    52561 tcagtatgct cagagctttt tcatctgcca agaacaaaac tgctttttga agttcttttt
    52621 gagagttttc aaggacatcc ttatctactg tttcaaggtt tgagtcttta agaagtttac
    52681 ttaattcctt ggctaatttc ttgagtttga tttgcagact catcttctcc tgctgtttct
    52741 ttgcccgctg tttgtcctcc atccttagtt gctgactggc tttccttaat ggactctagg
    52801 gaagcaatgg catctttgac tgtttgcaaa atatcacgta aaccttgctc tgtcaaacta
    52861 tcatctgcaa aagctttctt agcctctgcc aaaaccagac gtgctgaatc tgtggtagga
    52921 ttcgatacac ctgtcaatga tctcaaaaga ttttctaagg tttgagtctg cttactaata
    52981 ctagactaaa atcaaaaagc attatataac agtgatatga aatcaactaa agaagaaatc
    53041 caaactatca aaacactttt aaaagactct cgtacagcta aatatcataa acgccttcaa
    53101 atcgttctat agtaaaatga aacaagaaca ggacaaatcg atcaggacag tcaaatcgat
    53161 ttctaacaat gttttagaag tagatgtgta ctattctagt ttcaatccat tatatttcgt
    53221 ctgatgggca aatcttaata aagagattat agagctttta tagtgatttg aaataagatg
    53281 tgaacaactc tatcaggaaa gtcaaattaa tttatagaaa tattttagca gccaaggtgt
    53341 actgttataa attcaataca ct
//
LOCUS       DAVKEV010000007        52882 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVKEV010000007 DAVKEV010000000
VERSION     DAVKEV010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52882
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.007"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            265..501
                     /locus_tag="VWZ68_000419"
     CDS             265..501
                     /locus_tag="VWZ68_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEU9371505.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            732..2018
                     /locus_tag="VWZ68_000420"
     CDS             732..2018
                     /locus_tag="VWZ68_000420"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEU9371506.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            2219..2686
                     /locus_tag="VWZ68_000421"
     CDS             2219..2686
                     /locus_tag="VWZ68_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEU9371507.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            2719..2812
                     /gene="ffs"
                     /locus_tag="VWZ68_000422"
     ncRNA           2719..2812
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VWZ68_000422"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            2872..3315
                     /locus_tag="VWZ68_000423"
     CDS             2872..3315
                     /locus_tag="VWZ68_000423"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEU9371508.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            3317..3832
                     /locus_tag="VWZ68_000424"
     CDS             3317..3832
                     /locus_tag="VWZ68_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU9371509.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     TPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            3846..5207
                     /gene="radA"
                     /locus_tag="VWZ68_000425"
     CDS             3846..5207
                     /gene="radA"
                     /locus_tag="VWZ68_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEU9371510.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYISGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            5280..5777
                     /locus_tag="VWZ68_000426"
     CDS             5280..5777
                     /locus_tag="VWZ68_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEU9371511.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            5798..6142
                     /locus_tag="VWZ68_000427"
     CDS             5798..6142
                     /locus_tag="VWZ68_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371512.1"
                     /translation="MYEEKQYFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFANTYIHDFMNCTPKV
                     RQKKSNFWGVLL"
     gene            6139..7490
                     /locus_tag="VWZ68_000428"
     CDS             join(6139..6580,6580..7490)
                     /locus_tag="VWZ68_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU9371513.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNSMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRTKSFG
                     "
     gene            7496..8056
                     /locus_tag="VWZ68_000429"
     CDS             7496..8056
                     /locus_tag="VWZ68_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEU9371514.1"
                     /translation="MSNFLGSVHLLGVLFPDSTFLNAFESAIVAPLVEESLKLLPLVF
                     VLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIHTDLPEGFDFTISRILERIISGIAS
                     HWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLALGTHFLFNSPFVELETELPLAI
                     PVVTAIALYGFYHAYCFVEKHNELMT"
     gene            8201..9169
                     /locus_tag="VWZ68_000430"
     CDS             8201..9169
                     /locus_tag="VWZ68_000430"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU9371515.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            9287..9640
                     /locus_tag="VWZ68_000431"
     CDS             9287..9640
                     /locus_tag="VWZ68_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU9371516.1"
                     /translation="MTVRHPGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAQNVTIL
                     EGSNIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            9855..9971
                     /locus_tag="VWZ68_000432"
     CDS             9855..9971
                     /locus_tag="VWZ68_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU9371517.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            9964..10214
                     /locus_tag="VWZ68_000433"
                     /pseudo
     CDS             9964..10214
                     /locus_tag="VWZ68_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866636.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            10823..13456
                     /gene="polA"
                     /locus_tag="VWZ68_000434"
     CDS             10823..13456
                     /gene="polA"
                     /locus_tag="VWZ68_000434"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEU9371518.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVGTEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            13541..13978
                     /locus_tag="VWZ68_000435"
     CDS             13541..13978
                     /locus_tag="VWZ68_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEU9371519.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(14214..15224)
                     /locus_tag="VWZ68_000436"
     CDS             complement(14214..15224)
                     /locus_tag="VWZ68_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEU9371520.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSIVLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            15373..16542
                     /locus_tag="VWZ68_000437"
     CDS             15373..16542
                     /locus_tag="VWZ68_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9371521.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEVFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            16539..17309
                     /gene="recO"
                     /locus_tag="VWZ68_000438"
     CDS             16539..17309
                     /gene="recO"
                     /locus_tag="VWZ68_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEU9371522.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKCMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            17306..18298
                     /gene="plsX"
                     /locus_tag="VWZ68_000439"
     CDS             17306..18298
                     /gene="plsX"
                     /locus_tag="VWZ68_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEU9371523.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            18304..18537
                     /locus_tag="VWZ68_000440"
     CDS             18304..18537
                     /locus_tag="VWZ68_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU9371524.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            18583..18873
                     /locus_tag="VWZ68_000441"
                     /pseudo
     CDS             18583..18873
                     /locus_tag="VWZ68_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            19076..19306
                     /gene="blpU"
                     /locus_tag="VWZ68_000442"
     CDS             19076..19306
                     /gene="blpU"
                     /locus_tag="VWZ68_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEU9371525.1"
                     /translation="MNTKTMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            20021..22174
                     /locus_tag="VWZ68_000443"
     CDS             20021..22174
                     /locus_tag="VWZ68_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU9371526.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            22187..23536
                     /locus_tag="VWZ68_000444"
     CDS             22187..23536
                     /locus_tag="VWZ68_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEU9371527.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKVTASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKYVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            23706..24413
                     /locus_tag="VWZ68_000445"
     CDS             23706..24413
                     /locus_tag="VWZ68_000445"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU9371528.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNVAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            24415..24558
                     /locus_tag="VWZ68_000446"
     CDS             24415..24558
                     /locus_tag="VWZ68_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU9371529.1"
                     /translation="MFATENLRLSTKRTQAEKVPQTFSLCRELGELTDVYEIVWEKLQ
                     GLK"
     gene            24615..28340
                     /locus_tag="VWZ68_000447"
     CDS             24615..28340
                     /locus_tag="VWZ68_000447"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEU9371530.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            28433..29875
                     /locus_tag="VWZ68_000448"
     CDS             28433..29875
                     /locus_tag="VWZ68_000448"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEU9371531.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGVEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            30094..31116
                     /locus_tag="VWZ68_000449"
     CDS             30094..31116
                     /locus_tag="VWZ68_000449"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEU9371532.1"
                     /translation="MANKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIAGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            31113..31658
                     /gene="purN"
                     /locus_tag="VWZ68_000450"
     CDS             31113..31658
                     /gene="purN"
                     /locus_tag="VWZ68_000450"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEU9371533.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            31742..32251
                     /locus_tag="VWZ68_000451"
     CDS             31742..32251
                     /locus_tag="VWZ68_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU9371534.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            32276..33823
                     /gene="purH"
                     /locus_tag="VWZ68_000452"
     CDS             32276..33823
                     /gene="purH"
                     /locus_tag="VWZ68_000452"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEU9371535.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     ETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAANENQIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            33945..35207
                     /gene="purD"
                     /locus_tag="VWZ68_000453"
     CDS             33945..35207
                     /gene="purD"
                     /locus_tag="VWZ68_000453"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEU9371536.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVPTATYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGVIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            35610..36098
                     /gene="purE"
                     /locus_tag="VWZ68_000454"
     CDS             35610..36098
                     /gene="purE"
                     /locus_tag="VWZ68_000454"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEU9371537.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            36085..37176
                     /gene="purK"
                     /locus_tag="VWZ68_000455"
     CDS             36085..37176
                     /gene="purK"
                     /locus_tag="VWZ68_000455"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEU9371538.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            37186..37413
                     /locus_tag="VWZ68_000456"
     CDS             37186..37413
                     /locus_tag="VWZ68_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEU9371539.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            37476..38774
                     /gene="purB"
                     /locus_tag="VWZ68_000457"
     CDS             37476..38774
                     /gene="purB"
                     /locus_tag="VWZ68_000457"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEU9371540.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(38829..42767)
                     /gene="strH"
                     /locus_tag="VWZ68_000458"
     CDS             complement(38829..42767)
                     /gene="strH"
                     /locus_tag="VWZ68_000458"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU9371541.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLETLDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(43082..43798)
                     /locus_tag="VWZ68_000459"
     CDS             complement(43082..43798)
                     /locus_tag="VWZ68_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9371542.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            44146..45933
                     /locus_tag="VWZ68_000460"
     CDS             44146..45933
                     /locus_tag="VWZ68_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEU9371543.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            45930..46406
                     /locus_tag="VWZ68_000461"
     CDS             45930..46406
                     /locus_tag="VWZ68_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU9371544.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            46434..47339
                     /locus_tag="VWZ68_000462"
     CDS             46434..47339
                     /locus_tag="VWZ68_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU9371545.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            47326..48141
                     /locus_tag="VWZ68_000463"
     CDS             47326..48141
                     /locus_tag="VWZ68_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9371546.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            48148..48552
                     /locus_tag="VWZ68_000464"
     CDS             48148..48552
                     /locus_tag="VWZ68_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9371547.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            48805..49971
                     /locus_tag="VWZ68_000465"
     CDS             48805..49971
                     /locus_tag="VWZ68_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEU9371548.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCATDGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKV
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTAYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            50087..51124
                     /locus_tag="VWZ68_000466"
     CDS             50087..51124
                     /locus_tag="VWZ68_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEU9371549.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     IYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            51332..52186
                     /locus_tag="VWZ68_000467"
     CDS             51332..52186
                     /locus_tag="VWZ68_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9371550.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWNIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            52336..52593
                     /locus_tag="VWZ68_000468"
     CDS             52336..52593
                     /locus_tag="VWZ68_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEU9371551.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVKSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
BASE COUNT        14931 a         9825 c        12570 g        15556 t
ORIGIN      
        1 tgaatttttt tatactagaa aatcagaacc ataataccta tataaaaata ttatagtttt
       61 aataggattt acccaaaagt tttaaggcgg tctttttaga actttaattg tttgaaattt
      121 aggtagcaaa tttgtttcta ttttgtcaac ttttcctatt tttatcttgt tgaggctggt
      181 attttaacaa ttcaggaatt gatagtgaat gtgtaaaatt ttttgttaga ataagtttat
      241 aaaaaagaaa aggagtattt gattatgtta caaaaaattt atgagcagat ggctaatttc
      301 tatgatagta ttgaagaaga gtatggtcct acatttggtg ataattttga ctgggaacat
      361 gttcatttta aatttttaat ttattattta gtgagatatg gcattggttg tcgtagggat
      421 tttatcgttt accattatcg tgttgcttat cgtttgtatc ttgaaaaatt ggtaatgaat
      481 cgggggttta tttcttgttg aggtaatttt agtaaatttc cgaactaatt tactctttta
      541 tggaaagata atagtaaata gctagtaatt tttctaaatc attttttaat agttggaaat
      601 agcaaatctt tctattgttt cttcttgata aaaaggcgat tttttattat aataaattgt
      661 aagatataat tgcaggtgag agtcctgcca tgtatgtgag aaaggaagag cctgagggct
      721 cagacaaaat tatgacttca gttgttgttg taggtaccca atggggtgat gaaggtaaag
      781 ggaagattac agacttcctt tcagcgaatg cagaagtaat tgcacgttac caaggtggtg
      841 ataatgctgg tcacacgatt gtgattgacg gtaagaaatt taagttgcac ttgattccat
      901 ctgggatttt cttccctgaa aaaatatctg tcattgggaa tggtatggtt gtaaatccta
      961 aatctcttgt aaaagagttg agctatcttc atgaggaagg tgtaacaact gataacttgc
     1021 gtatttctga tcgtgcgcat gttattttgc cttatcatat cgagttggat cgcttgcaag
     1081 aagaagctaa gggcgacaat aagattggta cgacaattaa gggaattggt ccagcttata
     1141 tggacaaggc tgctcgtgtt ggaattcgta ttgcagatct tttagataaa gatattttcc
     1201 gtgagcgttt agaacgtaac cttgctgaaa agaatcgtct ttttgaaaaa ttgtatgaca
     1261 gtaaagcgat tgttttcgat gatatttttg aagaatatta cgaatatggt caacaaatca
     1321 agaaatacgt gatagataca tctgttatct tgaatgatgc gcttgataat ggcaaacgtg
     1381 tgctttttga aggtgcacaa ggtgttatgc tagatatcga ccaaggtact tatccatttg
     1441 ttacgtcatc aaaccctgta gctggtggtg tgacaattgg ttctggtgtc ggtccaagca
     1501 agattgacaa ggttgtaggt gtatgtaaag cttatacgag tcgtgtagga gatggtcctt
     1561 tcccaactga gttgtttgat gaagtgggag aacgtatccg tgaagtgggt catgaatatg
     1621 gtacaacaac tggtcgtcca cgtcgtgtag gttggtttga ctcagttgtg atgcgtcata
     1681 gccgtcgtgt ttctggtatt actaaccttt ctttgaactc tattgatgtt ttgagcggtt
     1741 tggatactgt gaaaatctgt gtggcctatg atcttgacgg tcaacgtatt gactactatc
     1801 cagctagtct tgagcaattg aaacgttgca agcctatcta tgaagagttg ccaggttggt
     1861 cagaagatat taccggagtt cgcaatttgg aagatcttcc tgagaatgcg cgtaactatg
     1921 ttcgtcgtgt gagtgaattg gttggcgttc gtatttctac tttctcagta ggtcctggtc
     1981 gtgaacaaac aaatatttta gaaagtgttt ggtcctaaga gatttttaag atttgtttaa
     2041 gataggtcgg gtatactata gacggttaca agaagacctc ctaacttgtt gtaacaaata
     2101 tcctaaactt ttctttttca taataatctc cctatagagt caccgcattc ggtggcttct
     2161 tttgtgttgg gattcatgat ataataataa aatcgataag taggaaaaga gaaaagagat
     2221 gtattatacg cttgaagaaa aagaagtctt tatgagggag gctttgagag aggctgagat
     2281 tgctcttgaa cacgatgaaa ttccaattgg ttgtgtgatt gtcaaagatg gggaaatcat
     2341 tggtcgtggg cataatgcgc gtgaggaatt acagcgagcg gttatgcatg cggaaattat
     2401 ggctatagag gatgcgaact tgagtgagga gagctggcgc ttgctggatt gcacactttt
     2461 tgtgaccatt gaaccttgtg tcatgtgtag tggagcgatt gggcttgccc gcattccaaa
     2521 tgtggtctat ggggctaaaa accagaaatt tggcgctgct gggagtttgt acaatatctt
     2581 gacagatgag cgtctcaatc atcgtgtgga ggttgaaata ggaattttgg aagatgaatg
     2641 cgcagctatc atgcaggatt tttttagaaa tagacggaaa aaataatttt gcttttaaaa
     2701 tgaataggaa tgtgatataa taaatagtgg agcaacagtt ctgcgtgaag cgggtcaggg
     2761 gaggaatcca gcagccctaa gcgatttgaa ttgtgtgctc ttttttcgtg ctttttccga
     2821 ataaataaga tagaataatc tagaataaat gataatagaa aagagaaaat tatgaaaatt
     2881 cgtggttttg aattggtttc gagttttaca gatgaaaatt tattgcccaa gcgtgagaca
     2941 gcgcatgcgg ctggttacga cttaaaggtt gctgtgcgta cagttgttgc gccaggagag
     3001 attgtcttgg ttccgacagg ggttaaggct tatatgcagc cgactgaggt tctctacctc
     3061 tatgatcgtt cttcaaatcc tcgtaagaag ggcttggttt taattaactc agttggggtc
     3121 attgatgggg attattatgg aaatcctgga aatgaagggc atatttttgc gcagatgaag
     3181 aatatcacag accaagaggt tgttcttgaa gttggggaac gtattgtcca ggctgttttt
     3241 gctactttct taattgcaga tggagatgca gctgatggcg ttcgaactgg tggatttgga
     3301 tcgacagggc actagaatga agattatctt tgtacgtcat ggggagccag attaccgtga
     3361 gttagaggag cgttcttata taggatttgg gatagatttg gcacccttgt ctgagatggg
     3421 acggcagcaa gtccagaaat tgagcaaaac tcctttactc tcgtcagctg aaataatcgt
     3481 atcttctgca gtcacaagag ctttagaaac ggcttcgtat gtggtctgtg ctacgggtct
     3541 tcctttaaga gtagagcctt tattacatga atggcaggtc tataaaacag gaatagaaaa
     3601 ctttgaaaca gctagaagac tgtttttaga aaacaagggg gagttgcttc ctaatagtcc
     3661 tattcaatat gagacagcta cggaaatgaa gtctcggttt ctagaatgta tgtctaagta
     3721 tcgagaacat cagactgtgg tagttgttgc tcatcgaatg ctcatgcgcc agtttgtgcc
     3781 aaatgagaag attgattttt gccaagtgat tgagtgtgag ttagagatat agaaagaggt
     3841 ttgtcatcgc aaagaaaaaa gcgacatttg tatgtcaaaa ttgtgggtat aattccccta
     3901 aatatctggg acgttgcccc aactgtgggt cttggtcttc ttttgtggaa gaggttgagg
     3961 ttgccgaggt caagaatgcg cgtgtgtcct tgacaggtga gaaaaccaag cccatgaaac
     4021 tagctgaggt gacttccatc aatgtcaatc gaaccaagac ggagatggag gaattcaacc
     4081 gtgtgcttgg aggcggagtg gtaccaggaa gtctcgtcct catcggtggg gatcctggga
     4141 ttgggaaatc aactcttctc ctacaagtct caacccagtt gtcccaagtg gggacagttc
     4201 tctatatcag tggggaggag tctgcccagc agattaaact acgtgcagag cgcttaggtg
     4261 atattgatag tgagttttat ctctatgcag agaccaatat gcagagtgtt cgtgcagaag
     4321 tggagcgtat ccagccagac tttcttatta ttgattccat ccagaccatc atgtctcctg
     4381 agatttcagg ggtgcagggg tctgtttctc aggtacgtga agtgaccgct gaactcatgc
     4441 agttggccaa gaccaataac attgccatct ttatcgtagg tcatgtgacc aaagaaggaa
     4501 ccttggctgg gcctcgtatg ttggagcata tggtggatac ggtgctttac tttgaagggg
     4561 agcgtcacca cacctttcgt attttgagag cggtcaaaaa tcgttttggt tccactaatg
     4621 agattgggat ttttgagatg cagtcgggcg gcttggttga ggtactcaat ccgagtcaag
     4681 ttttcctaga agagcgtttg gatggggcaa ctggttcctc catcgttgta accatggaag
     4741 ggacgcgtcc gattttggcg gaggttcagg ctttggtaac accgaccatg tttggaaatg
     4801 ccaagcgtac tacgacagga cttgatttta accgtgctag cttgattatg gctgttttgg
     4861 aaaaacgggc agggcttctc ttgcaaaatc aggatgccta tctcaaatct gctggtggtg
     4921 ttaaattgga tgaacctgcc attgacttgg ctgttgcagt tgctattgct tcgagctaca
     4981 aagacaagcc aactaatcct caggaatgtt ttgtcggaga actgggcttg acaggagaga
     5041 ttcggcgcgt gaatcgtatt gagcaacgca tcaacgaagc tgctaaactg ggctttacta
     5101 agatttatgt acctaagaat tccttgacag gaatcactct gcctaaggaa attcaggtca
     5161 ttggcgtgac aacgattcag gaagttttga aaaaggtctt tgcataatcc gtgacaaatt
     5221 ctcttaaaaa tgataagata ggagaaatat ttgactatca aattttcaag gagggaatcg
     5281 tgtcgtattt tgaacagttt atgcaagcta atcaggctta tgttgcccta catgggcagt
     5341 taaatctgcc acttaaaccc aaaacaagag tagctattgt gacctgtatg gactcacgtt
     5401 tgcacgttgc gcaagctcta ggtttggcac ttggggatgc tcatatcttg cggaatgcag
     5461 gtggtcgagt gactgaagac atgattcgtt cgctagttat ttcccagcaa caaatgggga
     5521 caagagagat tgtggtattg caccatacag actgtggtgc tcagaccttt gaaaatgaac
     5581 cttttcagga gtatttaaaa gaggaattag gtgtagatgt gtcagaccag gacttcttgc
     5641 ccttccaaga tatagaagag agtgtacgcg aggatatgca actgcttatc gagtctcccc
     5701 taataccaga cgatgtcatt atctctggtg ctatttacaa tgttgataca ggaagtatga
     5761 cagtcgtaga attataaata cttcatttag aaagaaagtg tatgaagaaa agcagtattt
     5821 tatttttatt ttattgctat gtattggttt acagtatgaa accatctact atacggacgg
     5881 ttcgaggtca ggtgcggaat atggactaat gggagtttct atctttctag ctctctttta
     5941 catgattccg gctctttatt ttctcttccg tattgggaaa aaatgggaat tgccaaagaa
     6001 ggttttgatt ctgtctttat tgggagggat gttcctttca ggctggttgt ctagttttgc
     6061 taatacttat atccatgatt ttatgaactg caccccaaaa gttagacaga aaaaatctaa
     6121 cttttggggt gttttattat gaaattgagt tatgaagata aagttcagat ctatgaacta
     6181 agaaagcaag gacaaagctt caaacagctt tcaaaaagat ttggtgtgga tgtttctggt
     6241 ctaaagtaca tggtgaaatt aattgaccgt tatggcatag aaatcgttaa aaaagggaag
     6301 aatcgtcact attcttctaa attgaaacaa gaaatgatgg ataaagcctt actggaaggt
     6361 tgttcacaaa gaagtattag tcttgattat gccctcccaa accaaggaat gctttcattt
     6421 tggccggcac aatacaagaa aaacgggtat actattgttg agaaaacaag agggagacca
     6481 gctaaaatgg gacgtaaacg gaagaagact tgggaagaaa tgacagaact agaacgactc
     6541 caggaggaga atgaacgctt acggactgag gtggcctacc taaaaaagtt aaaagagtta
     6601 gaggaaaggg acgaagccct agagcgagaa aggcagagac agttagagaa atggtttcag
     6661 gaggatttcg actagatttt cttcttgaaa cagcacgttt agctcgctcg acttactatt
     6721 atcagttgaa acaactggat ggggttgata aagataaaga gattaaaacc gaaattcagg
     6781 gcattgataa tgaacataaa ggcaactatg gctatcgtcg aatccattta gaactaagga
     6841 atcgtggttt tgtggtcaat cataagaaag ttcaacggtt gatgagaatt cttggtttaa
     6901 cggctcgaat tcgccgtaaa cggaagtatt cttcctacca aggagagatt ggcaagaaag
     6961 cagagaatct cattcaacgc cagttcgaag catcgaggcc aatggaaaag tgctatacag
     7021 atgtgacaga gtttgccatt ccaaatagca cacagaaact ctatttatca ccagttttag
     7081 atggttttaa cagtgaaatc attgcttatc atctttctac ttcgccaaac ttagaacaag
     7141 tgaagagtat gttagaacag gcctttacag agaaatacta tgagaatacg attctccata
     7201 gtgaccaagg ctggcaatac caacacgatt cttatcatcg gttcctagag agtaagggaa
     7261 ttcaagcatc catgtcacgc aagggcaaca gcccagacaa cagcatgatg gaatctttct
     7321 ttggcatttt aaaatccgaa atgttttatg gctatgagaa gaactttaga tctttagaaa
     7381 accttgaaca agctattgtg gactacattg attactacaa caacaaacga attaaggtaa
     7441 aactaaaagg acttagttct gtgcagtaca gaactaaatc ctttggataa attatttgtc
     7501 taactttttg gggtcagtac atttactggg ggttcttttc ccagatagta catttttaaa
     7561 tgcctttgaa agtgctattg tggctccttt ggtagaagaa tccttgaaat tattgccact
     7621 tgtttttgtt ttggctttga ttcctgtgcg aaaattaaaa tctttgtttt tacttggaat
     7681 tgcttccggt ttgggattcc aaatgattga ggatattggt tatattcata cggatttgcc
     7741 agagggcttt gactttacta tttcgcgaat tttagagcgt atcatctcag gaattgcctc
     7801 tcactggact ttttcaggtc tagctgtagt aggtgtttac ttgctttaca gagcctataa
     7861 aggacagaag gttggcaaga aacagggcct tatttttcta ggtttagcct tgggaactca
     7921 cttcttgttt aactctcctt ttgtggagtt ggaaacagag ttgcctttag cgattccagt
     7981 ggttacggct attgctctct atggttttta tcatgcttat tgctttgttg agaaacacaa
     8041 tgagttgatg acctagaata tttttcaaaa gaatgatgca agggtacaaa tatggtgccc
     8101 ttcttttatt tttgattgaa aaatagtgca aaaagcgcta caatggtaga tggaaaatct
     8161 tgtgaaaagc acaagttata catatatacc ggaggaaatc atgtcttttt ctgatttaaa
     8221 gctatttgcc ctttcttcta ataaagaatt ggcagaacgt gtggcgcagg agattgggat
     8281 agagttgggg aaatcaagtg ttcgccaatt ttcagatgga gagattcagg tcaacattga
     8341 agaatcaatc cgtgggaaac acgtctttat cctacaatca actagttcgc ctgtaaatga
     8401 caatctgctt gaaattttga ttatggtaga tgctttgaag cgtgcgagtg cagaatctgt
     8461 caatgttgtc atgccttact atgggtatgc acgtcaggat agaaaggcga gagcgcgtga
     8521 gccaatcact tcaaaacttg tcgcaaatat gcttgaagta gctggagtgg atcgtttatt
     8581 gaccatcgac ttgcatgctg cgcaaattca aggattcttt gatattcctg tggatcattt
     8641 gatgggtgct cctctgattg cagattattt tgagcgtcgt ggtatggttg gttctgacta
     8701 tgtggttgtc agcccggacc atggaggggt gactcgtgct cgtaagttgg cagaattttt
     8761 gaaaacttct atcgctatta ttgataaacg tcgtagcgtt gataagatga atactagtga
     8821 agttatgaac atcatcggta aggttgaagg caagacttgt atcttgattg atgatatgat
     8881 tgataccgct ggaacgattt gtcatgcggc agatgctctt gcggaagctg gtgctgttga
     8941 agtctatgca agctgtacgc acccagttct ttctggtcct gctacggaca atatccaaaa
     9001 atcagctatt aagaaattgg ttgttttgga taccatctat ctgccagaag agcgtttgat
     9061 tgataagatt gagcagattt caatcgctca tctcctaggg gatgctatcg tacgtattca
     9121 tgaaaaacga ccactttctc cacttttcga tattgagaaa aaaatttaat gaccaagcct
     9181 gagatgattc tcaggttttt tcgtcttttt tccgaataaa tagatagtag cggtgaatct
     9241 agtaaagcta gatttaaaac tgtgatataa taaaaagaga agaaatatga ctgtacgtca
     9301 tccgggcatt agcccaacca atgacttggt agctaagaaa atctttagca atccagaaat
     9361 tacttgtcaa tttattcgcg atatgctgga tttgccagcc caaaatgtga ccattttgga
     9421 gggtagcaat attcacgtat tactctccat gccttactcg gtgcaggatt tttataccag
     9481 tatagacgtc ttggcggagt tggataacgg tactcaagta attattgaga ttcaagtcca
     9541 tcatcagaat tttttcatca atcacttgtg ggcttacctg tgcagtcagg ttaatcaaaa
     9601 tcttgaaaaa attcgtcagc gagaaggtga tactcactag atctacaaac acatcgctcc
     9661 tgtttacgtc attgctatcg tggatagcaa ttatttctca gatggcctgg cttttcatag
     9721 cgttagtatg cgcgaagaca caacaggtga ggtattggcg attaccaaca atggacagga
     9781 aaaccatctg gttaagatgg cattcttgga attaaaaaat acagagaaac cagcaaagac
     9841 aaggttcgca agccatggtt ggagtttttc ggcaacaagc cctttaccca gcaaccgcaa
     9901 cgagccatta cccaagcaaa tcaactgctg gactacaaga gctggtccga ggaggacagg
     9961 aaaatgttta gtcaactaca tatgcgagaa gaacaagtct tgttagcaca ggactatgcg
    10021 aaggtattga acaaggacta gagcgtggta ttgaacgtgg tcgtgcagag ggttgtgaac
    10081 aaggacgaga agaaggcctt gaagagggat taaaagtagg tttagtaaat ctagtacgtc
    10141 aaggtcttct aacacctgag gttgcgagtg agcaattagg catgaccgtg gctgagtttg
    10201 agtccttgct atgagttcat actttatata gtagaaagtt gatgggatgg caagtttatt
    10261 atcaaaatac ttgtcatttt tgcttgacat ttctatcttt ttataagata tagtaaaatg
    10321 aaataataac aggacaaatc gttcaggaca gtcaaatcga tttctaacaa tgttttagaa
    10381 atcgaggtgt actattctag tttcaatcta ctatagtatt agcgaagtaa gttatgtctc
    10441 gctattcgta cagtttggat agtcgcaaga ttgtctttga aatttcctgt tttaaagaga
    10501 aaaaagcctc tttgacgcta ttttttcatc tttttgaaag ttctataatg aagttagcca
    10561 cccagccctc cttttcctcc ttctatagtg agttgaaata agatgtgaaa caactctatc
    10621 aggaaagtca aattaattta tagaaatatt ttagcagtca aggtgtacta ttatagattc
    10681 aatatactat attatatcac atttttaaat ctaggtttac taaattctct ggctctatct
    10741 atttattcgg aaaaagtttg aaaaatactt gctctagctc ttcccaatgg tattttttga
    10801 ttctttcctt tataatgggt gtatggataa gaaaaaatta ttattgattg atgggtcttc
    10861 tgtagctttt cgggcgtttt ttgcgctgta tcagcagttg gaccgtttta agaatgcggc
    10921 tggtttgcat accaatgcga tttatggttt tcagttgatg ttgagtcatt tgttggagcg
    10981 ggttgagccg agtcatattt tggtggcttt tgatgcggga aagacgacct tccggacaga
    11041 gatgtatgcg gactataagg gtggtcgggc caagactcct gatgagtttc gtgagcaatt
    11101 tcctttcatt cgtgagttgc tggatcatat ggggattcgt cactatgagc tggctcagta
    11161 tgaggcggat gacatcattg ggacgctgga taagctagca gagcaggatg gttttgatat
    11221 taccattgtc agtggggaca aggatttgat tcagctgacg gatgagcata cggtggttga
    11281 aatttccaag aaaggtgtgg ctgagtttga ggcctttacg ccagattacc tcatggaaga
    11341 aatgggcctc acaccagctc agtttatcga tctcaaggcg ctcatgggtg ataagtcgga
    11401 taatatccct ggggtgacca aagtcggtga aaagacgggt attaagctct tgctggagca
    11461 tggttcgctt gaggggattt atgaaaatat tgatggaatg aagacttcta agatgaagga
    11521 aaatctcatc aatgacaagg aacaggcctt tttgtctaaa acactagcga ccattgatac
    11581 caaggcaccg attgcgattg gtttagagga cttggtctat agtggtccag atgttgaaaa
    11641 tcttgggaaa ttttacgatg agatgggctt caaacagctc aagcaggctt taaatgtgtc
    11701 gtcagctgat gtggctgagg gtttggattt tactattgtt gaccaaatca gtcaagatat
    11761 gctgagtgaa gagtctatct tccactttga gctttttggt gagaattacc atacggataa
    11821 tttggttgga tttgcctggt cttgtgggga taagctctat gccacagaca agcttgagct
    11881 gttgcaagac ccgattttca aggatttctt agaaaaaaca tctctgagag tttatgactt
    11941 taagaaggtt aaagttcttt tgcaacgttt tggtgtggat ttgcaggcgc ctgcttttga
    12001 catccgtttg gctaaatacc tcctttcgac tgtggaggac aatgaaattg cgaccatcgc
    12061 tagtctttat ggtcagactt acttggttga tgatgaaact ttctacggta agggtgttaa
    12121 aaaggccatt cctgaacgtg agaaattctt ggaacactta gcttgtaaac ttgctgtttt
    12181 ggtaggaaca gagcctattt tacttgaaaa actcagcgaa aatgggcaat tagagcttct
    12241 ttatgatatg gagcaacctc tggcttttgt tcttgccaag atggaaattg ctgggattgt
    12301 ggtcaagaaa gagaccttgc ttgagatgca ggctgaaaat gagcttgtca ttgaaaaact
    12361 gactcaagag atttacgagc tggctggtga ggagtttaat gtcaactcgc ctaagcagtt
    12421 gggcgtgctt ctctttgaga aattgggact tcctctagaa tacactaaga aaaccaagac
    12481 aggttattcg acagcagtgg atgtgttgga gcgtctcgct cctattgctc cgattgttaa
    12541 gaaaatcctg gattaccgtc aaattgctaa gattcaatct acttatgtaa ttggcttgca
    12601 ggactggatt ttggctgatg gaaagattca tactcgctat atgcaggatt tgacccagac
    12661 cgggcgtttg tctagtgtgg atccaaactt gcaaaatatt cctgctcgat tggaacaagg
    12721 gcgcttgatt cggaaggctt ttgtgccaga gtgggaggat agtgtgctac tcagctctga
    12781 ctattcacag attgaattgc gcgttttggc gcatatttct aaggatgagc acttgattaa
    12841 ggccttccaa gagggggcag atatccatac ttcgacagcc atgcgggtct ttggcattga
    12901 gcgtcctgat aatgtgactg caaatgaccg tcgcaatgcc aaggcagtta actttggagt
    12961 ggtttatggg atttcagact ttggcttgtc taataatttg ggaattagtc gtaaggaagc
    13021 caaagcctac attgatacct actttgaacg ttttccaggt attaaaaact acatggatga
    13081 agtggtgcgg gaggcgcgtg ataagggcta tgtagagacc ctctttaagc gtcgccgtga
    13141 gttgccagat atcaattcgc gcaacttcaa tattcgtggt tttgcggagc gaactgctat
    13201 caactcacct atccagggtt cggcagcaga tattctcaag attgccatga ttcagctgga
    13261 taaagccttg gttgcaggtg gttatcagac taagatgctg ttacaagtgc acgatgaaat
    13321 cgtccttgaa gtgcctaaat ctgaattggt agagatgaaa aaattggtga aacaaaccat
    13381 ggaagaagcc attcaactca gtgttcctct tatcgcagat gagaatgaag gggcaacctg
    13441 gtacgaggct aaataaaaag ggggctagtc ctcctttttt gtagtagaat tctgcaaacc
    13501 ttttcaaaat gtgctatact gatgaaaaag gaggatttct atgagtcaag aatttatcaa
    13561 tccaagtgat ggcgtgattc gtcagtatct cgcaacgagt aaaacccttg ctgtggtggg
    13621 tttgtctgac cgtgaagaaa caactagcaa tcgagtaaca aaggaaatgc aggctcgggg
    13681 ctataaaatc atcccagtca atcccaaggc ggcaggtggc gaaatcttgg gtgaaaaggc
    13741 ttatgctagc ctcgctgaaa ttccttttcc tgtagatatt gtcaatgttt atcgtcgcag
    13801 tgaatttctg cccgatgtgg cgcgtgattt tctcaaagct gatgccaaga ttttttgggc
    13861 acagctagga cttgaaagtt tagaagcgaa agagattttg cgtgatggtg gatgtgatga
    13921 tatcgtgatg aatcgctgta tcaagagaga acatactcgc ttgattgagg aagcataaga
    13981 aaaaggtagc tgatgggcta ccttttgtgt tatactcaat gaaaatcaaa gagcaaacta
    14041 gcaaactagg aaactagccg cgggctgctc aaaacactgt tttgaggttg tagatagaac
    14101 tgacgaagtc agctcaaaac accgttttga ggttgcagat agaactgacg aagtcagtaa
    14161 catatatacg gcaaggcgac gttgacgtgg tttgaagaga ttttcgaaga gtattagaaa
    14221 atgccgataa gggtctgcat accaagagtg gtgaggatga tggcaatcca gcagatggct
    14281 ccgagaacaa tggattttcc actggatttg accatagcga ccagattggt tttgagaccg
    14341 atagcactca tggccatgac aatgaggaat ttagagagtt gtttgagagg ggtaaagaaa
    14401 ctactagaca caccgagaga ggtcagaagg gtggttagga gcgatgcaag gataaagtaa
    14461 aggataaaaa gtgggaagac ttttttcagt tgtaggcttt gcttgttttc ttgttggcga
    14521 ctttgccagt aggatagaaa gagcgtgata gggataatgg ccaaagtacg tgtgagttta
    14581 acaatggttg cagactcgag ggtattgctt tggtaaagac tgtcccaagc gctggcggca
    14641 gccgttacag aggaagtgtc gttgaccgca gtccctgcaa agagggcgaa gccttcattg
    14701 gatagatgaa gccaggtgcc gagggttgga aagatgagcg cagccaagac attgaagaaa
    14761 aagataacgg aaatggcttg ggctacttcc ttttccttag catcaataac gggcgctgtc
    14821 gctgcaatgg cagaaccccc acagatagaa gaacctactc caaccaaggt agccagtttt
    14881 gtatccagtg caaagaaacg ctggaagagg taggcaataa tcagagctat tgagatagtg
    14941 gacaggatga cagggagtga agattggcca actgcgaaga cctgcgagat attgagacca
    15001 aaaccaagca agacaacggc atattggagc aacttcttgg aactaaaggt caaaccagca
    15061 tccagttgtt tataggacga gagaaaggga tgtaggagca tgcctatgaa aatggcaaaa
    15121 acgggcgcgc caatcacagg gaagaatcct cctaagtacc aagataggat ggaaatgaga
    15181 aggcaggcca agatacctgc tccatttttt gatagaaatg acataaaaac ctccaaataa
    15241 aatctattac cattatagac ctataaacag gaaaagtaaa atagaaagtg gaaagctatt
    15301 ctctaatgta tttttgcggt cggggggctt ttgtagtata atagagatac gttttgaaag
    15361 taggaggtat ctatggactt aactaagcgc tttaataaac agttagataa aattcaagtt
    15421 tcgttgattc gtcagtttga ccaggctatt tcggagattc ctggggtctt gcgtttgacc
    15481 ttgggggaac ctgattttac aacgccagac catgtcaagg aggcggccaa gcgagcgatt
    15541 gatcagaacc aatcctacta tacagggatg agtggtctgc tgactctacg tcaggcagcc
    15601 agtgactttg ttaaggaaaa gtaccaactg gactatgctc ctgaaaatga aatcttggtt
    15661 acaattgggg cgacagaggc tttatctgcg actttgacgg ctattttgga agagggagac
    15721 aaggtacttt tgccagctcc tgcttatcca ggctatgaac cgattgttaa cttagttggg
    15781 gcagaaattg ttgagattga tacgactgaa aatggttttg tcttgactcc tgagatgttg
    15841 gagaaggcca ttttggagca gggtgataag ctcaaagcgg ttattctcaa ctatccagcc
    15901 aatccgacag gaattaccta cagtcgagag cagttagagg ccttggcagc tgttttacgc
    15961 aagtacgaag tttttgttgt ctgtgatgag gtttactcag aattgaccta cacaggcgaa
    16021 gcccatgtgt ctctaggaac gatgttgaga gaccaggcta ttattatcaa tggtttgtct
    16081 aaatcgcatg ccatgacagg ttggcgtttg gggctgattt tcgctccggc gaccttcaca
    16141 gcccagttaa tcaagagtca ccagtacttg gtcactgccg caaataccat ggcgcaacat
    16201 gctgcggtag aagccttgac ggctggtaaa aatgatgcgg agcccatgaa gaaggaatat
    16261 atccagcgtc gggactatat catcgaaaaa atgactgctc ttggttttga gattatcaaa
    16321 ccagacggtg ccttctatat ttttgctaaa attccagcgg gctacaatca agactccttt
    16381 gcttttctga aggattttgc tcagaagaag gccgttgcct ttatccctgg tgcagccttt
    16441 ggacgttacg gggaaggcta cgtccgccta tcttatgcag ccagcatgga gactatcaaa
    16501 gaagccatga aacgacttga ggagtacatg agagaagcat gattcagtct atcacgagtc
    16561 aaggcttggt gctttacaat cgcaattttc gtgaggatga caagctcgtc aaaattttta
    16621 cagagcaggt tggcaaatgc atgttttttg tcaaacacgc tggtcagtct aagctggcgc
    16681 ctgttattca gcccttggtg ctggcacgat ttctcttgcg aatcaatgat gacggactca
    16741 gttacatcga agactatcat gaggtcatga cttttcccaa gattaatagt gacctctttg
    16801 tcatggccta tgcgacctat gtggcagctc ttgcagatgc tagtttgcag gacaatcagc
    16861 aggatgctcc cttgtttgct tttttgcaaa agactttgga gttgatggaa gcaggcttgg
    16921 attatcaggt tttgaccaat atttttgaaa ttcaaatttt gactcgattt ggaatcagcc
    16981 tcaattttaa tgagtgtgtc ttctgccatc gggttggtca ggcttttgac ttttctttca
    17041 aatatggagc ctgcctctgt ccagagcatt atcatgagga taagagacgt tgtcatctca
    17101 atcccaatat cccctatctg ctcaatcaat ttcaagctat tgattttgag actttggaga
    17161 ccatttcgct caagcctgga atcaagcaag agctacgcca atttatggat caattatatg
    17221 aagagtacgt tgggattcac ctaaaatcaa agaaatttat tgattcccta gcagactggg
    17281 gacaattact aaaagaggaa aagaaatgaa aaaaatcgca gtagatgcca tggggggcga
    17341 ttacgcacct caggccattg ttgagggtgt caatcaagcc ctatctgact tttcagatat
    17401 cgaggttcaa ctttacggag atgaagctaa aatcaagcaa tatctgacag cgacagagcg
    17461 cgtcagcatt atccatacgg atgagaagat tgattcggat gatgaaccta cgagagctat
    17521 taggaataag aaaaatgcca gtatggtatt ggcagccaag gctgtcaaag atggtgaagc
    17581 agacgctgtc ctttcggctg ggaatacagg tgccttgttg gcagcaggat tcttcatcgt
    17641 gggtcgtatc aagaatatcg accgtcctgg actcatgtct accttgccta ccgttgatgg
    17701 aaaaggtttt gacatgctag accttggtgc caatgcagaa aatacagccc agcacctcca
    17761 tcaatatgcg gttctaggtt ccttctatgc taaaaatgtc cgtggcattg cgcaaccacg
    17821 cgttggtttg ctcaacaacg gaacagagag tagcaagggc gacccgcttc gtaaggaaac
    17881 ttatgaatta ctggcggctg atgaaagttt gaactttatc ggaaacgtgg aagcgcgtga
    17941 tttgatgaat ggcgttgcag atgttgttgt ggcagatggt ttcacgggaa acgctgtgct
    18001 caaatccatc gaagggacag ctatgggaat catgggcttg ctcaagacag ctattacagg
    18061 tggtggtctt cgagcgaaac taggtgccct ccttctcaag gacagcctca gaggtttgaa
    18121 aaaacagctc aattattcag atgttggtgg agcggtcttg tttggtgtta aggcacctgt
    18181 tgtcaagact catggctcaa gcgatgccaa ggctgtttat agtacgattc gccagattcg
    18241 taccatgcta gaaacagacg tagttgccca gactgcgcgt gaattttcag gagaataaaa
    18301 gagatgacag aaaaagaaat ttttgaccgt attgtgacca ttatccaaga gcgacaggga
    18361 gaggactttg tcgtgacaga atccttgagt ctgaaagacg atttggatgc ggattctgtt
    18421 gacttgatgg agtttatctt gaccctggaa gatgaattta gtatcgaaat cagcgatgaa
    18481 gaaattgacc aactccaaaa cgtaggagat gtggttaaaa tcattcaagg aaaatagcaa
    18541 tcggagttcc aagtcaacgg aagtagatgg tttttagaaa tgagaaatat cggacaagct
    18601 ggtaaaatct tggctgacag tggttatcaa gggctcatga agatatatcc tcaagcacaa
    18661 actccacgta aatccagcaa actcaagccg ctaacagttg aagataaagc ctgtaatcat
    18721 gcgctatcta aggagagaag caaggttgag aatatctttg ccaaagtaaa aacgtttaaa
    18781 atgttttcaa caacctatcg aaatcatcgt aaacgcttcg gattacgaat gaatttgatt
    18841 gctggtatta tcaatcatga actaggattc tagttttgca ggaagtctaa tagtaaaaaa
    18901 gtgattagaa aacatctttt ttaaaaatag agatgatttt gaaacaaaaa agctaattca
    18961 agacgtttcg atgccaattc aagatttgga tgaaaaaaat taatagatac tgttatacta
    19021 aacttgtcaa gtttgtaaca agacaaatat taaaaataaa aaagaggtat tcgttatgaa
    19081 tacaaaaacg atgtcacaat ttgaaattat ggatactgag atgcttgctt gcgttgaagg
    19141 tggcggatgc aattggggag attttgccaa agcaggtgtt ggaggaggag cagtacgagg
    19201 tcttcagcta ggaattaaaa caagaacatg gcaaggtgca gcaactggtg ctgcgggagg
    19261 agctatactt ggaggtgtgg cctatgcagc gacatgttgg tggtaattat ggattttaaa
    19321 agttttatta ttggtttagt agttggtata tttggtcctt atatggatga tttaattaga
    19381 aaaaaatttt taaagtcttc ggagaagaaa acagaaaaat ctgttaaaaa ataatcaaaa
    19441 ctataaatga tgaatctgaa tcaaaattat tttgcgcatg taaagaggag tcttatagta
    19501 acgagtcaaa aaaggagtaa ctatgaatcg taatttagaa cggtgttatc tattctgact
    19561 aggaatagat cataccagag gtagcttaga aatagcaggg acattagaaa ttgaagtaat
    19621 aaataggatg tcgtaagtgt tactatcaat gatttatttg tttcaagctt gcctagggtg
    19681 acagtaaaaa atcaatttcc tttcaatagc atatttttag tgggcaggac tcttgttctg
    19741 cctatttttt tatccaaaaa gtgcagttgg gagggagata ggctcatttg ggaaggaagt
    19801 ccagtttttg tttagtgatt ggggtaagat agttgttatc agatgagttt atactcttcg
    19861 aaaatcaaat tcaaaccacg tcaacgtcgc cttgccgtat atatgtgact gacttcgtca
    19921 gtcctatcta caacctcaaa acagtgtttt gagcagcctg cggctagttt cctagtttgc
    19981 tctttgattt tcattgagta ttagggaaaa ggagatgaat atgaaatttg ggaaacgtca
    20041 ctatcgtccg caagtggatc agatggactg cggtgtagct tcattagcca tggtttttgg
    20101 ctactatggt agttattatt ttttggctca cttgcgagaa ttggctaaga cgaccatgga
    20161 tgggacgacg gctttgggct tggtcaaggt ggcagaggag attggttttg agacgcgagc
    20221 cattaaggcg gatatgacgc tttttgactt gccggatttg acttttcctt ttgttgccca
    20281 tgtgcttaag gaagggaaat tgctccacta ctatgtggtg actgggcagg ataaggatag
    20341 cattcatatt gccgatccag atcccggggt gaagttgact aaactgccac gtgagcgttt
    20401 tgaggaagaa tggacaggag tgactctttt tatggcacct agtccagact ataagcctta
    20461 taaggaacaa aaaaatggtc tgctctcttt tatccctata ttagtgaagc agcgtggctt
    20521 gattgccaat atcgttttgg caacactctt ggtaaccggg attaacattg tgggttctta
    20581 ttatctgcag tctatcattg atacctatgt gccagatcag atgcgttcga cactagggat
    20641 tatttctatt gggctagtca tcgtctacat cctccagcaa atcttgtctt acgctcagga
    20701 gtatctcttg cttgttttgg ggcaacgctt gtcgattgac gtgattttgt cctatatcaa
    20761 gcatgttttt cacctcccta tgtccttctt tgcgacacgc aggacagggg agatcgtgtc
    20821 tcgttttaca gatgctaaca gtatcatcga tgcgctggct tcgaccatcc tttcgatttt
    20881 cctagatgtg tcaacggttg tcattatttc ccttgttcta ttttcacaaa ataccaatct
    20941 ctttttcatg actttattgg cgcttcctat ctacacagtg attatctttg cctttatgaa
    21001 gccgtttgaa aagatgaatc gggataccat ggaagccaat gcggttctgt cttcttctat
    21061 cattgaggac atcaacggta ttgagactat caagtccttg accagtgaaa gtcagcgtta
    21121 ccaaaaaatt gacaaggaat ttgtggatta tctgaagaaa tcctttacct atagtcgagc
    21181 agagagtcag caaaaggctc tgaaaaaggt tgcccatctc ttgcttaatg tcggcattct
    21241 ctggatgggg gctgttctgg tcatggatgg caagatgagt ttggggcagt tgattaccta
    21301 taataccttg ctggtttact ttaccaatcc tttggaaaat atcatcaatc tgcaaaccaa
    21361 gcttcagaca gcgcaggttg ccaataaccg tctaaatgaa gtgtatctag tagcttctga
    21421 gtttgaggag aagaaaacag ttgaggattt gagcttgatg aagggagata tgaccttcaa
    21481 gcaggttcat tacaagtatg gctatggtcg agacgtcttg tcggatatca atttaaccgt
    21541 tccccaaggg tctaaggtgg cttttgtggg gatttcaggg tcaggtaaga cgactttggc
    21601 caagatgatg gttaattttt acgacccaag tcaaggggag attagtctgg gtggtgtcaa
    21661 tctcaatcag attgataaaa aagccctgcg ccagtacatc aactatctgc ctcaacagcc
    21721 ctatgtcttt aacggaacga ttttggagaa tcttcttttg ggagccaagg aggggacgac
    21781 acaggaagat atcttacggg cggtcgaatt ggcagagatt cgagaggata tcgagcgcat
    21841 gccactgaat tatcagacag aattgacttc ggatggggca gggatttcag gtggtcaacg
    21901 tcagagaatc gctttggcgc gtgctctctt gacagatgcg ccggtcttga ttttggatga
    21961 ggcgactagc agtttggata ttttgacaga gaagcggatt gtcgataatc tcatggcttt
    22021 ggacaagacc ttgattttca ttgctcaccg cttgactatt gctgagcgga cagagaaggt
    22081 agttgtcttg gatcagggca agattgtcga agaaggaaag catgctgatt tgcttgcaca
    22141 gggtggcttt tacgcccatt tggtcaatag ctagaaagag gagaggatga aaccagaatt
    22201 tttagaaagt gcggagtttt ataatcgtcg ttaccataat ttttccagta gtgtgattgt
    22261 acccatggcc cttctgcttg tgtttttact tggctttgca actgttgcag agaaggagat
    22321 gagtttgtcc actagagcta ctgtcgaacc tagtcgtatc cttgcaaata tccagtcaac
    22381 tagcaacaat cgtattcttg tcaatcattt ggaagaaaat aagctggtta agaaggggga
    22441 tcttttggtt caataccaag aaggggcaga gggtgtccaa gcggagtcct atgccagtca
    22501 gttggacatg ctaaaggatc aaaaaaagca attggagtat ctgcaaaaga gcctgcaaga
    22561 aggggagaac cactttccag aggaggataa gtttggctac caagccacct ttcgcgacta
    22621 catcagtcaa gcaggcagtc ttagggctag tacatcgcaa caaaatgaga ccatcgcgtc
    22681 ccagaatgca gcagctagcc aaacccaagc cgaaatcggc aacctcatca gtcaaacaga
    22741 ggctaaaatt cgcgattacc agacagctaa gtcagctatt gaaacaggtg cttccttggc
    22801 cggtcagaat ctagcctact ctctttacca gtcctacaag tctcagggcg aggaaaatcc
    22861 ccaaactaag gttcaggcag ttgcacaggt tgaagcacag atttctcagt tagaatctag
    22921 tcttgctact taccgtgtcc agtatgcagg ttcaggtacc cagcaagcct atgcgtcagg
    22981 gttaagcagt caattggaat cccttaaatc ccaacacttg gcaaaggttg gtcaggaatt
    23041 gacccttcta gcccagaaaa ttttggaggc agagtcaggt aagaaggtac agggaaatct
    23101 tttagacaag gggaaagtta cggcgagtga ggatggggtg cttcatctta atcctgagac
    23161 cagtgattct agcatggttg cagaaggtgc cctactagcc caactttatc catctttgga
    23221 aagagaaggg aaagccaaac tcacagctta tctaagttca aaatatgtag caagaatcaa
    23281 ggtcggtgat tctgttcgct atactacgac tcatgatgcc gggaatcaac ttttcctaga
    23341 ttctactatt acaagtattg atgcgacagc tactaagact gagaaaggga atttctttaa
    23401 aatcgaggcg gagactaatc taacttcgga gcaggctgaa aaacttaggt acggggtgga
    23461 aggccgcttg cagatgatta cgggcaagaa aagttaccta cgttattatt tggatcaatt
    23521 tttgaacaaa gagtaatgtt cgtgttttta gagttaaata atttttaaac tgtgagaaag
    23581 attcttcttg cagttttttc tttacaattt ttgaaaaaca tctactattt attcggttaa
    23641 attcttgtgt tttttggttt tttgtggtaa aatgtgctca agtaatacga aaggcgaact
    23701 ttaaaatgtc aaaacaattg atctattcgg gaaaagctaa agatatctat acaactgagg
    23761 atgaaaatct tattatttca acttacaagg accaggcgac tgctttcaac ggtgtcaaga
    23821 aggagcagat tgcaggtaag ggagtcttga ataatcagat ctcatctttt atttttgaga
    23881 aattaaatgt ggctggtgtg gcgactcact ttgtggagaa actttcagac acggaacaac
    23941 tcaataaaaa ggttaagatt attcctttgg aagtcgtgct ccgcaactat actgctggtt
    24001 ccttttcaaa acgttttggt gtggatgagg gaatcgcctt ggagactccg attgtcgaat
    24061 tttactacaa aaatgatgat ttggatgatc catttatcaa tgatgagcat gtgaaattcc
    24121 tacagattgc gggtgaccag cagattgcct acttgaagga agaaacgcgt cgtatcaatg
    24181 aactattgaa agtctggttt gctgagattg ggcttaaatt gattgacttt aagctagagt
    24241 tcggttttga caaggatggc aagattatct tggcagacga attttcacca gataactgcc
    24301 gcttgtggga cgctgatggc aaccacatgg ataaggatgt tttccgtaga ggattgggag
    24361 aactaaccga cgtttatgag attgtttggg aaaagttgca ggaattgaaa taatctgttt
    24421 gcaacggaaa accttcgtct ctcaactaaa aggactcagg ctgaaaaggt cccccagacc
    24481 ttttcactct gtagagaact aggtgaacta acagatgttt acgaaattgt ctgggaaaag
    24541 ttgcagggtt taaaataaca acctcaaggc tgtttgggaa tattgcaaga gctgaaataa
    24601 aggaataaga attgatggat aaacgtattt ttgttgaaaa aaaggctgat tttcaggtca
    24661 agtcagagag tttggttaga gagctccagc acaacttggg actgtcaagc ttgaaaagta
    24721 ttcgtattgt gcaagtatat gatgtatttg acttggctga ggacttgttt gcacctgcag
    24781 agaagcacat tttctctgag cagggaaccg accatgtttt agatgaagta tctgtgcagg
    24841 cggatcttgc taactatgct ttctttgcca ttgaaagtct gccagggcag tttgaccagc
    24901 gtgcagcttc gtcacaggaa gccttgcttt tgttgggaag ttcgagtgac gtgacagtca
    24961 acacagccca actttacttg gtgaataaag atattgatgc gactgagttg gaagctgtca
    25021 aaaactacct gctcaatcca gttgattctc gtttcaagga tatcacgaca gggattgcca
    25081 agcaggagtt ttcagagtca gacaagacca ttccaaaatt gactttcttt gaaagctata
    25141 cagcagaaga ctttgctcgc tacaaggccg agcaagggat ggccatggaa gtggatgatt
    25201 tgctctttat ccaagactac tttaagtcaa tcgggcgcgt gccaactgag actgaactca
    25261 aggttttgga cacttactgg tctgaccact gccgtcatac gacttttgag acagagttga
    25321 aacacatcga cttttcagct tctaaatttc aaaagcaatt gcagtcaacc tatgacaagt
    25381 atattgccat gcgcgaggag ttaggtcggt ctgaaaaacc acaaaccttg atggatatgg
    25441 cgactatttt cggtcgttat gagcgtgcta acggacgatt ggatgatatg gaagtctctg
    25501 acgaaatcaa tgcctgctca gttgaaattg aagtggatgt tgatggtgtc aaggaacctt
    25561 ggctcctcat gtttaaaaat gaaacccaca accatccaac agaaattgag ccatttggtg
    25621 gagcggctac ctgtatcggt ggagctattc gtgatccgtt gtcaggccgt tcctatgttt
    25681 accaagccat gcgtatttca ggtgctggtg atattacagc accgatttcg gaaactcgtg
    25741 ctgggaaatt gccacaacaa gtcatttcta aaacagcagc tcatggttat tcttcatatg
    25801 gtaaccagat tgggcttgcc acaacctacg ttcgtgaata cttccaccca ggctttgtag
    25861 ctaaacgtat ggaacttggt gccgttgttg gtgcggctcc caagggcaat gttgtccgtg
    25921 aaaaacctga agcaggtgat gtgatcatcc ttctcggagg caaaacaggt cgtgatggtg
    25981 tcggtggtgc gacgggctct tctaaggttc aaacagttga gtctgtagag actgctggtg
    26041 ctgaggttca aaaaggaaat gccatcgaag aacgcaagat tcagcgcctc ttccgtaatg
    26101 gcaatgtcac tcgtctgatc aagaagtcca atgactttgg ggcaggcggc gtctgtgtgg
    26161 ctatcggtga attggcagac ggtcttgaaa tcgacctcaa caaggtgcct cttaaatacc
    26221 agggcttgaa tggtacagaa attgccatct ctgaatcaca agaacggatg gcggtcgtgg
    26281 ttcgtcctga agatgtggat accttcgttg ccgaatgtaa caaagaaaat attgatgctg
    26341 ttgtggtggc gacagtaact gaaaaaccaa atcttgtcat gcactggaat ggtgagacaa
    26401 tcgttgactt ggagcgtcgt ttccttgaca ccaatggtgt gcgcgtggtt gtcgatgcca
    26461 aagttgtgga caaggatgtc aaactcccag aagagcgtca aacatctgct gaaacactgg
    26521 aatcagatac ccttacggtt ctatctgacc tcaaccatgc aagtcaaaaa ggattacaga
    26581 ctatctttga ctgctctgtt ggacgctcaa cggttaatca cccacttggt ggtcgttacc
    26641 aactcacacc aactgaggca tctgtgcaga aattgccagt tcaacacggt gtgactcata
    26701 ctgcgtcggt cattgctcaa ggtttcaacc catatgtagc tgaatggtct ccataccacg
    26761 gtgctgctta tgcggttatc gaagcaactg ctcgtttggt ggctgctggt gccaactggt
    26821 ctaaggctcg tttctcttac caagaatatt tcgagcggat ggacaagcaa gcagagcgtt
    26881 tcggtcagcc agtagctgct cttctaggtt ctattgaagc acaaattcag cttggcttgc
    26941 catctatcgg tggtaaggac tccatgtctg gtacctttga agaattgacc gttccgccaa
    27001 ccttggttgc ctttggggtg acgacggcag atagccgtaa ggtgctctct ccagaattta
    27061 aagctgttgg ggaaaatatc tactacatcc caggtcaagc cctctctgca gagattgatt
    27121 ttgacttgat taagaaaaat tttgctcagt ttgaagcaag ccaagctgac cataaagtga
    27181 cgtctgcatc agctgtcaaa tacggtggtg tagttgaaag tttggctctt gctacctttg
    27241 gaaactatat tggtgcagag gtgaccttgc ctgaacttaa aacagctttg acagctcaat
    27301 taggcggctt tgtcttcaca tctcctgaag aaattgctgg agtagagaag attggacaaa
    27361 cgaaagcaga ctttacactg actgtcaacg gtgtgaagct agatggacac aagcttgaca
    27421 gtgcatttca agggacattg gaagaagttt acccaacaga atttacccaa gcgaaagaac
    27481 tagaagaagt accagctgtg gcatcagatg ttgtgattaa agccaaagaa aaggttgaaa
    27541 aacctgtggt ttacatccca gtctttccag gaaccaactc agaatatgat tcagctaagg
    27601 ccttcgaaaa agaaggtgca gaggtcaatt tggtgccatt cgtgaccttg aatgaagaag
    27661 ctattgtcaa gtcagttgaa actatggttg acaatatcga caagactaat attctcttct
    27721 ttgccggtgg attctcggct gcggatgaac cagatggttc agctaagttt atcgtcaata
    27781 tcctgcttaa tgaaaaagtg cgtgtggcta ttgatagctt tatcgcccgt ggtggcttga
    27841 ttatcggtat ttgtaatgga ttccaagcct tagtcaaatc gggtctccta ccatacggaa
    27901 actttgaaga tgctaacagt actagtccaa ccctcttcta caatgatgcc aaccaacacg
    27961 tggccaagat ggtggaaact cgtattgcca ataccaactc accatggttg gctggtgtgc
    28021 aagtgggcga tatccacgct attcctgttt cgcacggtga agggaagttt gtcgtgacgg
    28081 ctgaggaatt tgcagagctc cgtgacaatg gacaaatttt cagccaatac gttgacttta
    28141 acggtaaacc aagtatggat tctaagtaca atccgaatgg ttctgtccat gccatcgaag
    28201 gaattaccag caagaatggt caaatcatcg gtaagatggg ccactcagaa cgttatgagg
    28261 atggtctttt ccaaaatatc ccaggcaata aagaccaaca cctgttcgca tcagcggtta
    28321 aacatttcac tggaaaataa gacttacaga ttttctaata gatagtatca gtaatgtaaa
    28381 agtcatgtaa atctagctct tgatgattac aaatgaaaat taggtataaa aaatgacata
    28441 cgaagtaaaa tctcttaatg aagaatgtgg tgttttcggt atttggggac atccagatgc
    28501 tgctaagttg acctattttg gactccacag tcttcaacac cgtggtcagg agggggcagg
    28561 aatcctctcc aatgatcaag gacaactgaa gcgccatcgt gacatggggc ttttatcaga
    28621 agttttcaga aatccagcca atttggataa attgacagga gctggtgcga ttgggcatgt
    28681 gcgttatgcg actgctggcg aagcttctgt tgataacatc caacccttcc tcttccgttt
    28741 tcacgatatg cagtttggtt tggctcataa tggaaatctg accaatgcag cctctctcaa
    28801 gaaagaactg gaacaaagag gagcaatttt cagcgcgact tcggactctg aaatcttggc
    28861 tcacctcatt cgtcgcagtc ataatcctag cctgatgggc aaaatcaagg aagcgctcag
    28921 ccttgtcaaa ggtggttttg cctatatctt gctgtttgag gacaagttga ttgcggctct
    28981 tgaccctaat ggctttcgtc cgctttctat cgggaaaatg gccaacggag cggtggttgt
    29041 ttcctctgaa acctgtgctt ttgaggtcat tggtgtcgag tggatttgtg atttgaagcc
    29101 aggtgagatt gtgatcattg atgacgaggg cattcagtat gacagctata cagatgatac
    29161 ccagttggcg atttgttcta tggagtatat ctactttgcc cgccctgatt ctaatatcca
    29221 cggtgtcaat gtccatacgg cacgtaagag aatgggagcg caattggcgc gagaatttaa
    29281 gcatgaggca gatattgtag ttggtgtgcc caattcttcc ctaagcgcgg ctatgggatt
    29341 tgcggaagaa tcaggcttac caaatgaaat gggtctgatc aaaaaccaat acacccagcg
    29401 aacttttatc caaccgactc aagaattgcg ggagcaagga gtgcggatga aactgtctgc
    29461 tgtttcgggt gttgtcaaag gcaaacgtgt ggtcatggtg gatgattcca ttgtacgtgg
    29521 aacaacctct cgtcgtatcg ttcagctctt gaaagaagcg ggtgcgactg aggttcacgt
    29581 tgccattgga agtcctgcac tagcgtatcc atgtttctac gggattgata tccagacccg
    29641 tcaggagctg attgcagcca atcatacggt cgaagaaact cgccaaatca ttggtgcgga
    29701 cagtctgact tatctttcaa ttgatggctt gattgagtcg attggtatcg aaacagatgc
    29761 gccgaacggt ggtctctgtg tcgcttactt tgacggtgac tacccaacgc ctctctatga
    29821 ctacgaagaa gactatcgta gaagtttgga agaaaagacc agtttttaca agtaggcgac
    29881 agattctcca ttaaagaaaa ggaaaaaaca aatgacaaat aaaaatgcat atgcctcacg
    29941 tctcactact gactaaaggc ttaagcattt agtcagtaga cgctttgtcc tataggatca
    30001 aagctagagc cctgactagt atttttagat aaaaagatgg tttatctaaa aatacgtcgc
    30061 agtctttctc aaaaaaagaa aaggaaaaat aaaatggcaa ataaaaatgc gtacgctcaa
    30121 tctggtgtgg atgttgaagc gggttatgaa gttgttgaac ggattaaaaa gcacgtggct
    30181 cgtacggagc gtgcaggtgt catgggagct cttggtggct ttggtggtat gtttgacctt
    30241 tccaagactg gggttaaaga acccgtcttg atttcaggga ctgacggtgt cggaaccaag
    30301 ctcatgttgg ctatcaagta cgacaagcac gataccatcg ggcaggactg tgtggccatg
    30361 tgtgtcaacg acatcattgc tgcaggtgcg gaacccctct attttctcga ctacgtagcg
    30421 acagggaaga atgaaccagc taagctagaa caagtggttg ctggtgtggc agaaggttgt
    30481 gtgcaggctg gtgctgccct catcgctggg gaaacggctg aaatgccggg catgtacggc
    30541 gaagacgact atgacttggc tggttttgcg gtcggtgtgg ctgaaaaatc tcaaatcatt
    30601 gacggttcaa aggtggtaga gggagatgtt cttctcggac ttgcttcaag tgggattcac
    30661 tcaaatggtt actctttggt tcgtcgtgtc tttgcggatt acacaggtga ggaagtccta
    30721 ccagaattgg aaggcaagaa acttaaggaa gttctacttg agccgactcg tatctatgtc
    30781 aaggctgtct tgccgctcat caaagaagag ttggtcaacg gcattgccca catcacaggt
    30841 ggtggcttta tcgaaaatgt ccctcgtatg tttgcagatg acctagctgc tgaaattgat
    30901 gaaagcaaag ttccagtgct tccaattttc aaagcccttg aaaaatatgg tcagattaaa
    30961 cacgaagaaa tgtttgaaat cttcaatatg ggtgtgggac ttatgttggc ggtcagccct
    31021 gaaaatgtag agcgtgtaaa agaattgttg gatgaagcag tctatgaaat tggtcgcatc
    31081 gtcaagaaag aaaacgaaag tgtcattatc aaatgaaaaa aatagcggtt tttgcctctg
    31141 gtaatggctc aaattttcag gtgattgccg aagaatttcc agtggagttt gtcttttcag
    31201 accatcgtga tgcctatgtg cttgagcgtg caaagcagct cggcgttctg tcctatgctt
    31261 ttgaactcaa ggagtttgag agcaagacag actacgaagc agcccttgtc gaactcttgg
    31321 aagaacacca gattgacttg gtttgcctag caggctacat gaaaatcgtt ggaccaacct
    31381 tattgtcggc ttatgaaggt cggattgtca acattcatcc agcctacttg ccagaatttc
    31441 caggagctca tgggattgag gatgcttgga atgctggcgt gggtcagtct ggtgtgacca
    31501 ttcactgggt ggattcgggt gtggatacag gccaggtcat caaacaggtt cgtgtgccac
    31561 gactagctga tgataccatt gacagatttg aagctcgcat ccatgaagca gagtacaggt
    31621 tgtatccgga agtagtgaag gctctattta cagattgact ttttgatgat tcatatgata
    31681 tctttgattt taaattggag tcagtgtttg ttgaagacgg cttcaaacgg aggtatttgt
    31741 aatgttagaa tctaaaaaaa caactcgata tgtattttat gtctatctga tgttattaac
    31801 ttggggaatc ttatttaagt ttgaaacaaa tcctgaattt atagcatttt tcttagctcc
    31861 aaggtatatc aattggattc cattttcaga accactaata gtcgatggaa aaattgtttt
    31921 tgctgaaatg ttatttaatc tgatttcctt tattccatta ggtgtttgtt tccctttgat
    31981 aaaaactaat ttatctagtt taagaatagt cgggacaggt ttcttgatta gtttattgtt
    32041 tgagtgctta cagtatattt tagcaatagg tataacagat ataacggatt tgactttaaa
    32101 tacgctaggt gtctgtgtag gcttactgat ttatcaaatt tttataagag tgttcaaatc
    32161 acagactaga aaatggatca atatcttagg tatgcttagc cttggttttg cttatcttgt
    32221 tttactgtta ctgcatttaa ttggtgttta actaatgatt aaaaaggaga atataatgac
    32281 taaacgcgtc ttaatcagcg tctcagacaa agcgggcatt gttgaatttg cccaagaact
    32341 aaaaaaactt ggttgggaga ttatctcgac aggtggaact aaggttgccc ttgataatgc
    32401 tggggtggag accattgcga tcgatgatgt gacgggcttc ccagagatga tggatggccg
    32461 tgttaagact cttcatccaa atatccacgg gggtcttctc gctcgtcgtg atttggatag
    32521 ccacttggaa gcagccaatg agaaccaaat tgagcttatt gaccttgtag tggtcaacct
    32581 ttacccattt aaggaaacta tccttaaacc agatgtgact tatgctgatg cagttgaaaa
    32641 tatcgatatt ggtgggccgt ctatgcttcg ttcagcagcg aaaaatcatg ccagtgttac
    32701 agttgtggta gatcctgctg actacgctgt ggttttggac gaattggcag caaacggcga
    32761 aacctcttat gaaactcgcc aacgtttagc agccaaagta tttcgtcaca cagcggctta
    32821 tgacgccttg attgcagaat acttcacagc tcaagtgggt gaaagcaagc ctgaaaaact
    32881 cactttgact tatgacctca agcaaccaat gcgttacggt gagaatcctc aacaagacgc
    32941 ggacttttac cagaaagctt tgcctacaga ttactctatt gcttcagcca aacagctcaa
    33001 cgggaaagaa ttgtcattta ataatatccg tgatgcagat gctgctatcc gtatcatccg
    33061 tgacttcaaa gatagtccaa ccgttgtggc tctcaagcat atgaatccat gtggtatcgg
    33121 ccaggcggat gacatcgaga cggcttggga ttatgcttat gagtctgacc cagtgtctat
    33181 ctttggtggt atcgttgttc ttaaccgtga ggtggatgct gcgacagctg agaagatgca
    33241 cggcgttttc ctcgaaatca tcattgcacc aagctatacg gatgaagcgc tagctatttt
    33301 gatcaataaa aagaaaaact tgcgtatcct tgccttgcca tttaatgctc aagaggctag
    33361 cgaagtggaa gcagaataca caggtgtagt cggtggactt ctcgtgcaaa atcaagacgt
    33421 ggtcaaggaa agcccagctg actggcaagt ggtgaccaaa cgtcagccaa ccgagacaga
    33481 agcgactgct cttgagttcg cttggaaggc tatcaagtac gtcaaatcaa atggtattat
    33541 cgtgaccaac gatcacatga cacttggtgt tggtccaggt caaaccaacc gtgtggcttc
    33601 tgttcgcctt gccattgacc aagccaaaga tcgtctggac ggggcggtcc ttgcttcaga
    33661 tgccttcttc ccatttgcgg ataacgtgga agaaatcgcc aaagcaggaa ttaaggccat
    33721 catccagccc ggtggctctg tccgtgacca agaatccatc gaagcagcgg ataaatatgg
    33781 cttgactatg gtctttacag gtgtgagaca ttttagacat taagaagata aaagggaaga
    33841 aaacagtttc tttccttttt tggcttaaaa tgctaactga aacaagatta aaacgaactt
    33901 ttttgatata atgttggtaa ataattcgca aaagaggttg aggaatgaaa ctgcttgttg
    33961 tcggttctgg tggtcgtgag catgcgattg ctaaaaagtt acttgaatca aaagacgtgg
    34021 aaaaagtctt tgtagctcct gggaatgatg ggatgactct ggatggtttg gaattggtaa
    34081 atatctctat ttccgaacat tctaaattga ttgacttcgc aaagaccaat gatgttgctt
    34141 ggacctttat cggtccagat gatgcccttg ctgctggtat cgtggatgat tttaaccaag
    34201 ctggacttaa ggcctttggt ccgactaggg ctgcagcgga gctggagtgg tccaaggatt
    34261 tcgccaagga aatcatggtc aaatacggcg ttccgacagc aacatatggc acattttcag
    34321 atttcgagga agccaaggcc tatatcgaaa agcatggtgc gcctatcgta gtcaaggcgg
    34381 atggcttggc acttgggaag ggtgtcgtcg ttgctgagac ggttgagcaa gcggtcgaag
    34441 ccgctcatga gatgcttttg gacaataaat ttggtgactc aggtgcgcgc gtggttattg
    34501 aggaattcct tgaaggagag gaattttcac tctttgcctt tgtcaatggt gataagttct
    34561 acatcatgcc aacggctcag gaccacaaac gtgcctatga tggcgacaaa gggcctaaca
    34621 cgggtggtat gggtgcctat gcgccagtcc cacacttacc acagagtgta gttgatacag
    34681 cggttgacac cattgtcaag ccagttctag aaggggtgat taaagaaggt cgcccttatc
    34741 tgggagttct ttacgcaggg cttatcctga cagctgatgg accgaaagtc attgagttca
    34801 acgctcggtt cggagatcca gaaactcaga ttatcttgcc tcgcttgacc tctgactttg
    34861 ctcaaaatat cacagatatc ctggatagca aggagccaaa tatcatgtgg acggacaagg
    34921 gtgtgactct gggtgtggtt gtcgcatcca agggctaccc gctagactat gaaaggggcg
    34981 ttgagttgcc agcaaagaca gaaggcgatg tcatcaccta ctatgcaggg gctaagtttg
    35041 cggaaaatag cagagcactg ctctcaaacg gcggacgagt ttatatgctc gttaccacag
    35101 cagataccgt caaagaagcc caagccagca tctaccaaga actatcccaa caaaaaatag
    35161 aaggactctt ctaccgaaca gatatcggaa gcaaggcaat taagtaaaga tataagaata
    35221 acgcgccgta gtcgccaaac acgataatgg tcgtcgtggt gaaaagacca gaacagtgaa
    35281 tgttctggtc agggggaaac ttggagacct taggctcaaa gtttaggaat gaaaccgaag
    35341 gtttgcttcc gcctccatca cctaagacca ttatcaaaaa gaaaaataaa aattcacaaa
    35401 atacgttaat gatcgtatgg tttgcgagcg ttagcgagct aatatagaac aatcaccgcc
    35461 gttgtgaaag aacgattgga tgataatcca atcgttcagg gaaattggaa gaccttgggt
    35521 ttccaattta ggcatgagac acctttggtg gctgctgccg tccctcacaa gctaaggtga
    35581 ttgttgaaaa agaggaaaaa ggagaagaaa tgaaaccagt aatttccatc atcatgggct
    35641 caaaatccga ctgggcaacc atgcaaaaaa cagcagaagt cctagaccgc ttcggtgtag
    35701 cctacgaaaa gaaagttgtt tccgcacacc gtacaccaga cctcatgttc aaacatgcag
    35761 aagaagcccg tagtcgtggc atcaagatca tcatcgcagg tgctggtggc gcagcgcatt
    35821 tgccaggcat ggtagctgcc aaaacaaccc ttccagtcat tggtgtgcca gtcaagtctc
    35881 gtgctcttag tggagtggat tcactctatt ctatcgttca gatgccgggt ggggtgcctg
    35941 ttgcgaccat ggctatcggt gaagctggag cgactaacgc agctctcttt gccctccgtc
    36001 tcctctctgt agaagataag tccattgcgg atgcacttgc caactttgct gaagaacaag
    36061 gaaaaatcgc agaggagtcg tcaaatgagc tcatctaaaa caatcggaat tatcggtggc
    36121 ggtcaactgg gtcagatgat ggccatttct gctatctaca tgggccacaa ggttatcgcg
    36181 ctggatcctg cggcggattg cccggcctct cgcgtggcgg aaatcattgt ggcaccttat
    36241 aacgatgtgg acgccctccg tcagttggca gaccgttgcg atgtcctcac ttacgagttt
    36301 gaaaatgtcg acgctgacgg tttggatgcc gttatcaagg atggacaact ccctcaagga
    36361 acagatctgc tccgcatttc gcaaaatcgt atttttgaaa aggacttttt gtcaaacaag
    36421 gctcaagtca ctgtggcacc ctacaaggtc gtgacttcta gcctagactt ggcagatatc
    36481 gacttgtcga aaaactatgt cctcaagact gcgactggtg gctacgatgg tcatggacaa
    36541 aaggttattc gttcagaagc agacttggaa gcagcctatg cgctagcaga ctcagcagac
    36601 tgcgtcttgg aagaatttgt caactttgac cttgagattt ctgtcatcgt gtcaggaaat
    36661 ggcaaggagg tgacgttttt cccagttcag gaaaatatcc accgcaacaa tatcctgtct
    36721 aagaccatcg taccagcccg catttctgaa agtctagcag acaaggctaa agctatggca
    36781 gtgcgaatcg cagaacaact caacttgtct ggaactctct gtgtggaaat gtttgcgact
    36841 gatgatgacg ttattgtcaa tgaaatcgcc ccacgaccac ataactctgg gcactattct
    36901 attgaagcct gtgatttctc tcagtttgac acccatattc tcggtgttct cggagcacca
    36961 ttaccagtca tcaaactcca tgcgccagcc gttatgctta atgtcctcgg tcagcatgtc
    37021 gaggctgctg agcaatatgt gacagaaaat tcaagcgccc acctccacat gtatggtaaa
    37081 atagaagcga agcacaaccg caagatggga catgtgacct tgtttagtga tgtaccggat
    37141 agtgtggatg agcttgggga agggattgat ttttaggaca agtctatgat acaaattatc
    37201 gttaatacat ttattgaaaa ggataagact ggagcagttg ttgaagtgtt gtatgccagt
    37261 gctgaccaag ataaggtaca agctaaatat gaagaactag ctgcacaata ccccgaaaat
    37321 tatttagcta tctatgatgt accgctggat acggatttga atacactaga tcattacccg
    37381 tctgtgttta ttgaaaaaga ggagtttgag tagaaatctt ggtttaccta gatagcttat
    37441 tcccaacagc ttaagaagaa aggaaaaatt aacacatgat caaccgttac tctcgccctg
    37501 agatggcgaa tatttggagt gaagaaaata aataccgtgc ttggcttgag gtggaaatcc
    37561 tctctgacga ggcatgggct gagttggggg aaatccctaa ggaagatgtg gctttgattc
    37621 gcaagaaggc ggactttgac atcgaccgta ttttggaaat tgagcaggag acgcgccacg
    37681 atgtggtggc tttcacgcgt gcggtttctg agactcttgg tgaagagcgc aagtgggttc
    37741 actatgggtt aacttctacc gacgtggtgg atactgctta tggttacctc tacaagcagg
    37801 ccaacgacat catccgtcgt gaccttgaaa acttcactaa tatcatcgct gacaaggcca
    37861 aggagcacaa gttcaccatc atgatggggc gtactcatgg tgtgcacgct gagccgacaa
    37921 cctttggtct taaattggca acttggtaca gcgaaatgaa acgcaatatc gagcgtttcg
    37981 agcatgcagc tgctggtgta gaagctggta agatttctgg tgcggttggg aactttgcca
    38041 atatcccacc atttgtagag gagtatgtct gcgataaact tggcatccgt gcccaagaaa
    38101 tctctacaca agtccttcct cgtgaccttc acgctgagta ctttgcggtt cttgccagca
    38161 ttgcgacttc aatcgaacgt atggcgactg agattcgtgg tctacaaaaa tctgagcaac
    38221 gcgaagtaga agagttcttt gctaaagggc aaaaagggtc ttcagcaatg cctcacaaac
    38281 gcaacccaat cggttctgaa aatatgactg gtctggcgcg tgtcattcgt ggtcacatga
    38341 ttacggctta tgaaaacgtc gctctctggc acgaacgcga tatttctcac tcatcagctg
    38401 agcgtatcat cacaccagat acgaccattt tgattgacta catgctcaac cgttttggaa
    38461 atatcgtcaa gaacttgaca gtcttcccag aaaatatgat ccgaaacatg aactcgactt
    38521 ttggtcttat ctttagccaa cgggctatgt tgacattgat tgaaaaaggc atgacccgtg
    38581 agcaagccta tgacttggtg caaccaaaaa cagcctactc ttgggacaac caagtagact
    38641 ttaaaccact tcttgaggca gattcagaag taacatcacg tctcactcaa gaagaaatcg
    38701 atgaaatctt caacccagtt tattacacca aacgagtgga tgatatcttt gaacgtcttg
    38761 gactaggtga ttaattaaaa aataaacagc gagcttcaat ctcgctgttt attttttatc
    38821 gaaaagactt agtcttcttt tcttttagtg agtccatagg ctgctagtgt ggacatgagt
    38881 cctgcgacta ctagtcctgc agaatcgtga gttcctgttt caggaagttt tttctctgtt
    38941 accacaggag ctggatcttg aggaagagct ttgctttcct cagcaggagc agttgatgga
    39001 gctggttggc ttgggatttc tagttttggt ttttcttcag caatagcggc ttgtccgttt
    39061 tcatcgccta catgtgttac catagttccg acttcgacta tttgagtaac ggcttcctgt
    39121 gctacgacac tatttacaag tgttttcact tccttaccat cggcagaagt gctcacagag
    39181 tagaagttgc tacgatgtcc attgacgccc ttagtaatga cttgtgtttt tcctttgagt
    39241 aagagtggat tttcacgagt cactgtggta aatggaattt cttctttttg gatatccagt
    39301 ctaggtttta cctcagtagt tggtgcaaga ccactttcat cacccttgtg agttacagga
    39361 gcgccaactt caaccacttg gtttataact tctttggtta cctggctatc aaggactgtt
    39421 tctgttgttt ttccattttc agtgagtaca gagatgtaat gagttcgttc acctttgact
    39481 cctgctgtga taatattttc ctgaccagct gggaggttag gattttcttt cttgataact
    39541 tcaaatggaa tttcttcagt tcttgtgatg agttctggtc tggtttcaac attggcagcc
    39601 acttcatttt catctaggct tcctgaatga gttgcagctg gtttgaggcc ttgaagagcg
    39661 gcttttaggt tggctacaag tgtgtcaagc tcagcttgtt tattacggtt gaggttgtaa
    39721 tttagagctg ttttagctgc gtcaagggtc tcaagacttt ctttactata tccttctaag
    39781 tttgtaggaa ttttagctaa ttcttcgcgg agagcattat aattagcacg gaagtagtct
    39841 ttgttgtggt ctgcaaaggc agtcatgagt tcaaagattt cctcttcctt gtattcagcg
    39901 cttggtctat ctgcccagat tgaaagcata cttccgactg ttggaagatc tacttcagga
    39961 tatttggtag aagctagttg attgaatggt gtttttccag tattctcaat agctttcttg
    40021 aggaaaccac caccatcttc tggtttttga ccaagaatgt agtaccagtc accgttggta
    40081 ttcaagaatt tatagccttt gcttgctagg tattgaggtg atgcgaggtt atatccccac
    40141 cagcctttag accagtaaga aatcaagaca tctttgtcaa actgaacatc gtccttgtct
    40201 tcatagtaga agccatcgtt gaaggccatt ggttgaagcc ctctttcttt ggccatagct
    40261 gcgagggtgt tggcatattc ggcaaatttg ccatagagtt gataccactt gaggtagtac
    40321 cagccttggg cactagtcgc atcgttggcg tattcgtcag taccaaagtt gaaaatcttt
    40381 gttttacctg caaagaagtc catgtattta ccgatgaggg cttttacaaa gttcatcgct
    40441 tcttcgtttt tcaagtccat agttgttttt gaaactttat caaagtgggc ttgaggattt
    40501 ttaataccta atttttccat ggcaaccagc atagcatcca tgtgacctgg actgttaata
    40561 gctgggatga gaccgatgtc cttagattta gcgtattcaa ttagctctgt tacttctgcc
    40621 tgtgttagtg cagtaccgtt tggatcgtcg tagtaagctt tagttccttc gataatagct
    40681 tttttaacgt catcactagc ataggttttt ccgttggcag taatggtcat atcatcgagt
    40741 agaaagcgaa gtccgtcatt tcctagaagg agatggacat cagaatatcc gagctcactg
    40801 gccttgtcta cgatgcgttt gagctggttc agagtaaagt atttgcgtcc agcatcgatt
    40861 gagattacct tgtttttggc aagtttttca acctcacgtt tagcttcttc ttctttttga
    40921 gcttcaggcg tgagggtcaa gttgttgaca gtttcttgaa gtttagcaat ggcttgatca
    40981 atcgtatctt gttgggcacg gctaaggttg ctatcgagag agcgaatagc tttttcagct
    41041 tcttttacgg ccgtgacgct ttctgcagta taacggttca ggtcttttgg tacctcgtta
    41101 agtgcttgct ctgcagattc ataatcagct gcgaagtatt cagcgttggc atttgcaaaa
    41161 tgacgcatga gtttgaagag gcgtgatggt gaataacgtg cagatggagt gtcagcccaa
    41221 gcagctacca taccaccgat gattgggata tcagctcctt ctgtttttgg tacagaagtg
    41281 attggtgtgt ttttaatacc attgagcccc tgatcgagat tgtaccagcc ttggccatca
    41341 gcgtttcgtc caagaacgta gtaccaagca tcattggtat taaggatttg gtgacctttt
    41401 tcagctagta gtttagaaga agcgacatcg tagcctcccc aaccaccagt ccacatagaa
    41461 acgatgatgt ctttgtcaaa actaccaaag cttgtgtcgc tattgtagta gataccgtcg
    41521 ttaaaggcca ttggtttgag accgtgcgat tttacaatac gagcgaggtc attggcgtag
    41581 gcaataaatt tttcatagcc ttttacaggg tagccttcgt ttggatagta tttatcagct
    41641 tgaagcacac tccaaccttt agcatctgtc gcatcattgg catattcatc aagtccgatg
    41701 ttgaagattt cagtcttttt cgcgaaataa gcagcatact tgtcgataag ggcttttgta
    41761 aaagcgacag cttgttcgtt gtcaagatcg acagtacggg ctgatttctt cccaaaatag
    41821 ctaaagttag ggttttggat tcccaattct ttcatggcat tgagaatcgc atccatgtgt
    41881 ccaggactat ttactgtcgg aatgagaccg atacctttat ctttggcata gttaatcaga
    41941 tctgtcattt gactttctgt taagtgattg ccgtttggat cgttgtaata atcatttgta
    42001 cctttttcaa tggcgcgttt gacatcgtca ctggcatagg tcttgccgtt agctgtgatg
    42061 ctcatatcgt ccaacatgaa acggagtcca tcatttccga ctaataggtg taaatcagtg
    42121 tagccataat gtttcgcttt atcgatgatt tccttgagct gttctggtga gaaatattta
    42181 cgtccagcat caatagaaac aattttcttt ttcgctagtt tttcatttac agttgcagca
    42241 cgttcctttc ctgcctctgt ttccggtttg tcagcctctg ctttcgcttc atctttttta
    42301 gctggtttat ccttgtcagt cttgtctgta tttgactctt tagaatcaac ctctttcgct
    42361 tcttcctttt tagggctagc ttcttctgcc tttttattag cagtttcttt ttcagcagaa
    42421 gttggagtta ccacttctgc tttatcacta ggagttgaac taacttcctc ttgtggtttt
    42481 tcttctgttt ttggaagact agctacctta tcagtagctg gagtttctgt ttctacagtt
    42541 tttggagctt ctggttgaag ctctgcttta ggtgtttcct cagtccgatt ttcggatgat
    42601 tgaggggaat cagaaaccgt atggatggtc ggttggtttt ctgtagtagt aggagtaact
    42661 ccatcggctg caacagtctg tgcttggaag gcaaatccaa ttagaacaga agctgctcct
    42721 acagcgtatt tacgaataga aaaacgctgt tgtttttcat gtttcattgc aaaacctcct
    42781 gattgcattg ttatattgat agcgattata taaatcaacg cctttatttt atttcttata
    42841 ttaacgagag tcaagaggag atgacaaaaa actataataa gtataaaaaa atataaaatt
    42901 taaacttaag atttcagatt ggtcggaaaa aatgaatata tatatctagt ataatttttg
    42961 gttctatttc tataaaatat tccacaaatt atagaatctt ccaaaaatag gtaagcgcta
    43021 cctttttggt gtggtataat aagcatagaa aaagcccaag cgattagctc aggctttctt
    43081 cttagtgatc acggtcacat gagataaatt taatcttgta gtaatcagat cgtttgtaag
    43141 tttcactgta ttctaaaact tggccagttg attcgagttt ggtgatttta gtttgtagga
    43201 cagtagggaa ttgttcatcg actccgagga ctgaagccgc atgttctgga gttggaaaga
    43261 ctatttcgtt gatttcttca aagtgttcat cattcatgtg aatgtggtag tctaacttga
    43321 aacgattata gatagaacta tagtattcaa ggtttggata atttgcgttg atatattgtt
    43381 ctgggatgta ggatgtatgg tagatataaa cgacaccgtt tgattcgcgg atacgttcaa
    43441 tcttgtagta gaattgatcg ccgcgtagac ccaatttttc caagtaaaca agcttgtttc
    43501 cgcgttcaat tgaaagaaca gttaccttat catctttagc attgaagagt tcaatatctg
    43561 aaaactctac aagcttgtgt ttgcgcgcac gtgaaacgaa ggttcctttt ccttgttggc
    43621 ggacaatata gccatctttg gcaaggtcgt ttaaggcgcg aacaactgtg atagagctga
    43681 catcgtacat tgaaatgagt tctgcttcag tgtaaaattt atctccactg ctaaactgcc
    43741 cagagatgat tttatttttt aattcgtctt ttatgtattg atatttggga attgccatat
    43801 ttttacctct attttccttc tccatagaaa attttaccat aaaagcgaaa aaaatagtag
    43861 tcttttgaat aaaaaattag aataatagtt tgaaaaatta agcgatatag ggattgctca
    43921 tattttataa atgtattcta tacaaaatta ttttaggtcc tatattccga atttaaagag
    43981 cgtttgaaat gggtctaaaa atgtttgaaa ctaattgaat gtgtgtataa tagtaaaaat
    44041 gcagtaaata tcccgacaat ttctattgac aattcaaaca gattggttta taattaatat
    44101 aacaacaaat gaaagcgcaa actttcgcgg tcggaaggta gttttatgac acgatttgag
    44161 atacgagatg atttctatct cgatggaaaa tcatttaaga ttttatctgg tgccattcat
    44221 tattttaggg ttcctccaga ggattggtat cattcgctct ataacttgaa ggctcttggt
    44281 tttaatacgg tagagactta tgttgcttgg aatttacacg agcctcgtga aggtgagttt
    44341 cattttgacg gtgatctgga tttagagaaa tttctccaaa tagcgcagga tttgggtctc
    44401 tacgcaattg tgcgtccgtc tccatttatc tgtgcggaat gggaattcgg tggcttacca
    44461 gcttggctct tgaccaagaa catgcgaatt cgctcatccg acccagcata tatcgaggca
    44521 gttggtcgct actatgatca gttattgcca agactggttc ctcgtttgtt ggacaatggt
    44581 ggcaatattc tcatgatgca ggttgaaaat gagtatggtt cttacggaga agataaggct
    44641 tacctgagag cgattcgaca gctaatggaa gagtgtggcg taacctgtcc cctctttaca
    44701 tcagatggtc catggcgagc tactctgaaa gctggaacct taattgaaga ggacctcttt
    44761 gtaacaggaa actttggttc taaggcacct tacaactttt cgcagatgca ggaattcttt
    44821 gatgaacatg gtaagaaatg gccactcatg tgtatggagt tctgggatgg ttggtttaat
    44881 cgttggaaag aaccgattat cacacgggat cctaaggaat tggcagatgc agttcgagaa
    44941 gttttggaac aaggctccat caatctttac atgttccacg gtggtacaaa ctttggtttc
    45001 atgaatggtt gctcggctcg aggaactttg gacctgccac aagttacgtc ttatgattac
    45061 gatgcccttc tggatgaaga aggaaatcca actgctaaat atcttgcagt caagaagatg
    45121 atggcaacac atttttcaga gtatccgcag ttggaaccac tctacaaaga gagtatggag
    45181 ttggatgcta ttccactagt tgaaaaagtt tctttgtttg aaaccttaga tagcttgtca
    45241 agtcctgtag aaagtctcta tcctcaaaag atggaggagc tgggacaaag ttatggctac
    45301 ctactttatc gaacagaaac aaactgggat gcagaagaag aaagacttcg tatcattgat
    45361 ggtcgagata gggcccagct gtatgtcgat ggtcagtggg ttaaaactca atatcagaca
    45421 gagattgggg aagatatttt ttatcaaggt aaaaagaaag ggctatctag gttagatatc
    45481 ttgatagaaa atatggggcg tgtcaactat gggcataagt tcttagcgga tacgcaacgt
    45541 aagggaattc ggacaggggt ctgtaaggat ctgcatttct tactaaactg gaaacactat
    45601 ccactcccac tagacaatcc tgagaaaatt gatttttcaa aaggatggac tcaaggacaa
    45661 ccagcctttt acgcttatga ctttacagtc gaagagccaa aagatactta cctagacttg
    45721 tctgagtttg gtaagggggt tgcctttgtc aatgggcaga atctaggacg tttttggaac
    45781 gttggcccaa ctctctcact ttatatccct catagctatc tcaaggaagg tgccaaccgc
    45841 atcattatct ttgaaacaga aggtcaatat aaagaagaga ttcatttaac tcgtaaacct
    45901 acactaaaac atataaaggg ggaaaactta tgacaattgt aggatgccgt attgatggac
    45961 gtttgatcca cggacaagta gccaatcttt gggctggaaa actaaatgtt tcacgcatta
    46021 tggttgtaga cgacgaagtt gtcaacaacg atattgaaaa gagtggtttg aaacttgcga
    46081 caccaccagg tgtgaaattg agtattttgc cagttgagaa agctgcagcc aatattcttg
    46141 ctggcaaata cgatagccaa cgtctcttta tcgtggctcg taaaccagac cgcttccttg
    46201 gtttggtaga agcaggtgta ccacttgaaa cccttaatgt tgggaatatg tctcaaacac
    46261 cagaaactcg ttctattaca cgttctatca acgtagtaga caaggatgtg gaagacttcc
    46321 acaaactggc agaaaaaggt gttaaactta ctgctcagat ggttccaaat gatccaattt
    46381 cagacttttt gagcttatta aaataggaaa aaatttttta ggaggtcatt gttatgatac
    46441 aatggtggca aattttactt ctcactttgt actcagctta tcaaatctgt gatgagttga
    46501 cgatcgtttc atctgcaggt tcccctgtat ttgctggttt cattactggt ttaatcatgg
    46561 gagatgtgac tactggttta cttatcggtg gtaacttgca actgttcgtt cttggggttg
    46621 gtaccttcgg tggtgcttct cgtatcgacg caacttctgg tgcggttctt gcgacagcct
    46681 tctctgtttc acaaggaatt gatgcaccgc ttgcaattac tacaatcgct gtaccagtag
    46741 cagctctctt gacttacttc gacgttcttg gtcgtatgac tactaccttc ttcgctcacc
    46801 gtgtggatgc tgcaatcgaa cgctttgact ataaaggtat tgaacgcaac tacttgcttg
    46861 gtgcgattcc gtgggctcta tctcgtgccc ttccagtctt ctttgccctt gcttttggtg
    46921 gtgcctttgt acaatcagta gtagacttcg ttgaagccta caaatgggtt gcagatggct
    46981 tgacactcgc aggacgtatg cttccaggtc ttggatttgc aatcttgctt cgttaccttc
    47041 cagttaaacg taaccttcac taccttgcta tgggatttgg tttgacagct atgttgactg
    47101 ttctttactc atatgtaaca ggtcttggtg gcgctgttgc tggtatcgta ggtactcttc
    47161 ctgctgaagt tgctgaaaaa attggtttcg tgaacaactt caaaggtttg tctatgattg
    47221 gtatttctat cgtaggtatt ttccttgcag tgcttcactt caaaaatagc caaaaagtag
    47281 ctgtagcagc accttctaca ccatcagaaa gtggggaaat cgaagatgac gaattctaat
    47341 tacaaactta caaaagaaga ttttaatcaa atcaacaaac gtagcttgtt tactttccaa
    47401 ttaggttgga actacgaacg tatgcaagct tctggttacc tttacatgat cttgcctcag
    47461 ttgcgtaaaa tgtatggtga tggaactcct gaattgaaag aaatgatgaa agttcatact
    47521 caattcttca atacttcacc attcttccat accattatcg ctggttttga ccttgccatg
    47581 gaagaaaaag atggtgtagg ttcaaaagac gctgttaacg gtatcaagac aggtttgatg
    47641 ggaccattcg ctcctcttgg ggatacaatc tttggttcac ttgtacctgc tatcatgggg
    47701 tcagtcgcag caactatggc tatcgctggc caaccttggg ggatcttcct ttggattgca
    47761 gttgcagtag cgtatgacat cttccgttgg aaacagttgg aatttgctta caaagaaggg
    47821 gttaacctta tcaacaacat gcaaagtacc ttgacagctt tgattgacgc tgcatctgta
    47881 cttggtgtct tcatgatggg tgctcttgta gcaacagtga ttaactttga aatttcttac
    47941 aagttgccaa tcggtgaaaa gatgattgat ttccaagaca tcttgaacca aatcttccca
    48001 cgtttgcttc cagcaatctt tactgccttt atcttctggt tgcttggtaa aaaaggtatg
    48061 aactctacta aagctatcgg tattattata gtacttgctt tggctctttc tgcccttggt
    48121 cactttgcac ttggaatgta attccttatg actaaatcat taattttggt gagccatggt
    48181 cgcttctgtg aggagcttag aggtagcaca gaaatgatta tgggcccaca agacaacatt
    48241 tacacagtag ctcttcttcc agaagatggc ccagaagaat ttactgctaa atttgaagct
    48301 gttattgaag gattggatga tttcctagtc tttgcggatc ttctcggtgg gacaccttgt
    48361 aatgtggtga gtcgcttgat catggaaggt cgtgatattg acctttacgc agggatgaat
    48421 cttccaatgg tgattgaatt tatcaatgcg agccttacag gcgcagatgc ggactacaag
    48481 agccgtgctg cagaaagcat tgtgaaagtt aatgacctgt tagcgggctt cgatgatgac
    48541 gaagatgaat aatactcttc gaaaatctct tcaaactacg tcaacgtcgc cttgccgtag
    48601 gtatatgtta ctgacttcgt cagtcttatc cggcaacctc aaagcggtgc tttgagcagc
    48661 ctgcggctag tttcctacag attttagttg gaactcgatt caattcatgt gacaacgtga
    48721 aaatcgttag agcattttat atagaatata catgggaatg gagcttactc ccattcccat
    48781 atttaataga aaaagaggaa ctcaatgcta cattatacaa aagaagactt gctcgaattg
    48841 ggtgcagaaa tcactacgcg tgaaatctac caacagcctg atgtatggag agaagctttt
    48901 gaattttatc aagcaaaacg tgaagaaatt gcagcctttc tacaagaaat cgctgataaa
    48961 catgactata ttaaggttat cttgacaggt gctgggactt ctgcttatgt gggagatacc
    49021 ttgctacctt actttaagga agtctatgac gaacgcaaat ggaatttcaa tgctattgcg
    49081 acaacagata tcgttgccaa accagcaacc tatttgaaaa aagatgtggc aactgtcctt
    49141 gtgtcttttg ctcgtagtgg gaactcgcct gaaagtgtgg cgactgttga tttggccaaa
    49201 tccttggtgg atgagcttta tcaagtgacg attacttgtg caacagatgg taaattggct
    49261 cttcaagctc acggtgatga ccgtaatctc ttgctcttgc aaccagctgt ctctaatgat
    49321 gctggatttg ccatgacttc tagctttacg tctatgatgt tgacagctct cttggtcttt
    49381 gatcctacag aatttgctgt taagtctgaa cgttttgaag ttgtatctag tcttgcccgt
    49441 aaagttttag acaaggtaga agatgtcaaa gagctcgttg atttagactt taaccgtgtc
    49501 atctatctag gcgctggtcc tttctttgga cttgctcatg aagctcagct caagattttg
    49561 gaattaactg ctggtcaagt tgcgaccatg tatgaaagcc cagttggctt ccgtcacggt
    49621 ccaaaatctc ttatcaacga caatacagtt gttttggtct ttggtacaac gacagcctac
    49681 actcgtaagt acgacttgga cttggttcgt gaagttgctg gtgaccagat tgctcgtcgt
    49741 gttgtgcttt tgagtgatca agcttttggt cttgaaaatg tcaaagaagt ggtccttggt
    49801 tgtggcggtg tcttgaatga tatttaccgt gtcttccctt acatcgttta tgcccaactc
    49861 tttgctctat tgacttcact caaggtagaa aataaaccag atacaccgtc tcctacaggt
    49921 acagtaaacc gtgtagtaca aggtgtcata attcacgaat atcaaaagta agacagtgtt
    49981 tatgaattct tgacaagagg atttgtaaat tatcagataa accatagatt gtcagtacgc
    50041 tttctatggt ttgtttgctt gagagaaata gtaaaaggag aacagaatga aagcatacac
    50101 agagcgtgta tttggaaatg ttgagggcga ggatgtcttg gcctatcgat ttgagacaga
    50161 cggtggctac caacttgagg ttatgactta tggcgcgacc atcttgcgct atgtcgcacc
    50221 tgacaaggct ggaaattttg ccaatgttat cttgggattt gatgactttg atagttatgt
    50281 aggcaatagt cccaagcatg gagcaagtgt aggtcctgta gcgggtcgta ttgcaggtgc
    50341 gacctttgag ctcaatggta agacctatga ccttgaggtt aataatgcta gcaactgtaa
    50401 tcacagtggt tcaactggtt gggattccag cttgtttgaa gttgaagaag taagcgatca
    50461 tggcttgact ctctacacag agcgtacaga tgggacagga gggttccctg gaaatctcaa
    50521 gatttggatc agttatcact tggaagaaac tggtgcctat gaaatcatct acaaggtaac
    50581 gaccgatcag gatacgctgg tcaatccaac caaccacagc tatttcaact tgtctggtga
    50641 tttcacgcag acgattgacc gtcatgtctt ccaactaaac acagagggca tttactcaat
    50701 cgctcctgac ggtgttcctg ccaaaactcc agaagccaac cgtgatgtgg tcaaacacat
    50761 ctacaatggt accttgttga aggatatctt tgcagaagaa gatgagcaaa tccagctggc
    50821 atcaggtttg gatcacccat ttgcccttcc tgcaggccat gacaatgctg gattccttta
    50881 tgaccaaaat tcaggtcgct tcctgctttt caagacagaa gctccttgct ttgtggtcta
    50941 cacagcaaac tttgtggatg aaagtgtcat cataggaggt cagccaatgc tacagcacaa
    51001 tgggattgct cttgaagcgc aagctttacc agatgccatt cacagtgacc ttaaaggcca
    51061 agtcattctt aaagctggtc aaaccttcac cagtaagaca cgttatgaac ttgttgtgaa
    51121 ataaaaaaag ctggtcaaaa agtctttaaa attaaaataa cgcatattgt caggtgatga
    51181 aaagtttgat aatatgcgtt ttattatgaa atgatttact ttatcttatc ctgaaatggt
    51241 gttatttttg agttatctgg cttgactttc ttgatggaaa ttatataata gttgtaataa
    51301 caataattac aacgagaaaa gaggaccatt tatgacctat gaatacaaga gtcacattta
    51361 tttggcagag acagttttaa atgtaaagga tttggccagt caaacagcct tttatcagca
    51421 agttattggt ttagaaatct tatctcaaac tgagacagag tccattctag gccttggtgg
    51481 aaaagtcttg gtacagctga ttcaagcaca agagagcgga gaagtgaggg aacattatgg
    51541 tctttaccat ttggccattc tcttgcccac acgcaaggct ttggctgatg tcttgaaaca
    51601 cctgacagat ttgcaaattc ctcttgtcgg cggtgcagac catggttaca gtgaagctat
    51661 ttacttggaa gatttggagg gaaatggcat tgaactctat cgagataagc cagtttccac
    51721 atggaatatt cgagaagatg gacgcattat cggagtgacg gaggctcttg cggcgcagga
    51781 catttatgag ttgggggaaa gagtagagcc ctttatcctg gcagaaggta caagaatggg
    51841 gcatattcat ctttccgtca aggatagtcg aaagtccagc cagttttatc aaaaggtgtt
    51901 agggctagag aataaattca gtgtgcctgg cgctagttgg attgcggctg gagattacca
    51961 tcatcattta gcagttaacg aatggggagg aaaaggtctg gcttcgcgta agcaaggctt
    52021 accaggttta gcctactatg tcatcgaagt cgcacataaa aaagaactgt taacgattgc
    52081 ccaacgagca caagaagttg acgcaccaat caaatggatg acatcgagcc aattggaaat
    52141 cacagactca gatggcatcg tgacccgtat tcgtttagca aggtaaaatt aggaattttt
    52201 aataagttat aagtattgct agtttgcttt ttgaacggtc tttggtaaca gaactgcgtg
    52261 agctggatgg gtgagaattt tgacaaagaa gctgattaga gatataatga agaaaaatcg
    52321 agcaaggaaa aagaaatgac aaattcaaag tatattactt gtttgaaacg ttcagagggc
    52381 cagttgtgtg gaattcaaaa gatgattgaa ggagatcgtg actgtgctga tattgtgacg
    52441 caactgacag cagtgaaatc tagtgtagag cgcgtgattg agatgataat taccgaaaat
    52501 cttactgaat gtatcaatca gccactagat gattctgaag ctcaaaagga acgcctagaa
    52561 aaggctatcc gatacttgat taaacggaaa taaatgaatg ttttgagacg atatgtgcaa
    52621 aggtctatta actattagaa tagtttaatg tgagtcaaaa gaagttgtaa aaaatcttta
    52681 aaattaaaaa acgcatagta tcaggtattg aaatgtactg ccccccaaaa gttagattct
    52741 ttctgtctaa cttttggggg gcagtacata aaaaccttga tagtatgcgt tttattgtgg
    52801 ggagacttat actcttcgaa aatctcttca aaccacgtca gtttcacctt gccgtagata
    52861 tggttactga cttcgtcagt tc
//
LOCUS       DAVKEV010000008        51519 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVKEV010000008 DAVKEV010000000
VERSION     DAVKEV010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51519
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.008"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..1387)
                     /gene="pcpA"
                     /locus_tag="VWZ68_000469"
     CDS             complement(<1..1387)
                     /gene="pcpA"
                     /locus_tag="VWZ68_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEU9371552.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNRGV"
     gene            1656..1838
                     /locus_tag="VWZ68_000470"
     CDS             1656..1838
                     /locus_tag="VWZ68_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU9371553.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            1783..2632
                     /locus_tag="VWZ68_000471"
                     /pseudo
     CDS             1783..2632
                     /locus_tag="VWZ68_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(2684..3046)
                     /locus_tag="VWZ68_000472"
     CDS             complement(2684..3046)
                     /locus_tag="VWZ68_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371554.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNIEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(3337..5217)
                     /locus_tag="VWZ68_000473"
     CDS             complement(3337..5217)
                     /locus_tag="VWZ68_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU9371555.1"
                     /translation="MVRFIGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRHDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(5211..6080)
                     /locus_tag="VWZ68_000474"
     CDS             complement(5211..6080)
                     /locus_tag="VWZ68_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9371556.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(6164..8809)
                     /locus_tag="VWZ68_000475"
     CDS             complement(6164..8809)
                     /locus_tag="VWZ68_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEU9371557.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(8900..10180)
                     /locus_tag="VWZ68_000476"
     CDS             complement(8900..10180)
                     /locus_tag="VWZ68_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEU9371558.1"
                     /translation="MVYSKEIVREWLDEVAERAKDYPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIKNYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            10352..12436
                     /locus_tag="VWZ68_000477"
     CDS             10352..12436
                     /locus_tag="VWZ68_000477"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEU9371559.1"
                     /translation="MKPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKSSAQVDWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEINESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMTPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(12476..14155)
                     /locus_tag="VWZ68_000478"
     CDS             complement(12476..14155)
                     /locus_tag="VWZ68_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU9371560.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQTGETEKSLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            14910..16139
                     /gene="arcA"
                     /locus_tag="VWZ68_000479"
     CDS             14910..16139
                     /gene="arcA"
                     /locus_tag="VWZ68_000479"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEU9371561.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESEYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            16197..17213
                     /gene="argF"
                     /locus_tag="VWZ68_000480"
     CDS             16197..17213
                     /gene="argF"
                     /locus_tag="VWZ68_000480"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEU9371562.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            17378..18325
                     /gene="arcC"
                     /locus_tag="VWZ68_000481"
     CDS             17378..18325
                     /gene="arcC"
                     /locus_tag="VWZ68_000481"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEU9371563.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            18536..20047
                     /locus_tag="VWZ68_000482"
     CDS             18536..20047
                     /locus_tag="VWZ68_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEU9371564.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            20069..21400
                     /locus_tag="VWZ68_000483"
     CDS             20069..21400
                     /locus_tag="VWZ68_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEU9371565.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEENLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     LLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            21495..21622
                     /locus_tag="VWZ68_000484"
                     /pseudo
     CDS             21495..21622
                     /locus_tag="VWZ68_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836165.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fucose isomerase"
     gene            complement(21787..22077)
                     /locus_tag="VWZ68_000485"
     CDS             complement(21787..22077)
                     /locus_tag="VWZ68_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371566.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(22065..22316)
                     /locus_tag="VWZ68_000486"
     CDS             complement(22065..22316)
                     /locus_tag="VWZ68_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU9371567.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFDGMGDQPVQDTE
                     TSSALILSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            22520..22597
                     /locus_tag="VWZ68_000487"
                     /pseudo
     CDS             22520..22597
                     /locus_tag="VWZ68_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(22715..23599)
                     /locus_tag="VWZ68_000488"
     CDS             complement(22715..23599)
                     /locus_tag="VWZ68_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU9371568.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(23744..24895)
                     /locus_tag="VWZ68_000489"
     CDS             complement(23744..24895)
                     /locus_tag="VWZ68_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEU9371569.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(25041..26807)
                     /locus_tag="VWZ68_000490"
     CDS             complement(25041..26807)
                     /locus_tag="VWZ68_000490"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEU9371570.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPIMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(26890..30006)
                     /locus_tag="VWZ68_000491"
     CDS             complement(26890..30006)
                     /locus_tag="VWZ68_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU9371571.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVSFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKEDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNDYEVFTQHIDSLESNNLSIDLKGLKGKKVRISLRSAGIPLSLA
                     EVEVYTYK"
     gene            complement(30016..32310)
                     /locus_tag="VWZ68_000492"
     CDS             complement(30016..32310)
                     /locus_tag="VWZ68_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU9371572.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTVFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(32369..33169)
                     /locus_tag="VWZ68_000493"
     CDS             complement(32369..33169)
                     /locus_tag="VWZ68_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9371573.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(33166..33939)
                     /locus_tag="VWZ68_000494"
     CDS             complement(33166..33939)
                     /locus_tag="VWZ68_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU9371574.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(33964..34434)
                     /locus_tag="VWZ68_000495"
     CDS             complement(33964..34434)
                     /locus_tag="VWZ68_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9371575.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(34425..34856)
                     /locus_tag="VWZ68_000496"
     CDS             complement(34425..34856)
                     /locus_tag="VWZ68_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9371576.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(34846..35289)
                     /locus_tag="VWZ68_000497"
     CDS             complement(34846..35289)
                     /locus_tag="VWZ68_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEU9371577.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENVQ"
     gene            complement(35301..35939)
                     /locus_tag="VWZ68_000498"
     CDS             complement(35301..35939)
                     /locus_tag="VWZ68_000498"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEU9371578.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            complement(36054..37457)
                     /locus_tag="VWZ68_000499"
     CDS             complement(36054..37457)
                     /locus_tag="VWZ68_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEU9371579.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKEE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            37633..38406
                     /locus_tag="VWZ68_000500"
     CDS             37633..38406
                     /locus_tag="VWZ68_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9371580.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(39566..41071)
                     /gene="adcA"
                     /locus_tag="VWZ68_000501"
     CDS             complement(39566..41071)
                     /gene="adcA"
                     /locus_tag="VWZ68_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEU9371581.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYHTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(41081..41887)
                     /locus_tag="VWZ68_000502"
     CDS             complement(41081..41887)
                     /locus_tag="VWZ68_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU9371582.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(41880..42584)
                     /locus_tag="VWZ68_000503"
     CDS             complement(41880..42584)
                     /locus_tag="VWZ68_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU9371583.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            complement(42584..43024)
                     /gene="adcR"
                     /locus_tag="VWZ68_000504"
     CDS             complement(42584..43024)
                     /gene="adcR"
                     /locus_tag="VWZ68_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEU9371584.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(43179..44447)
                     /gene="dltD"
                     /locus_tag="VWZ68_000505"
     CDS             complement(43179..44447)
                     /gene="dltD"
                     /locus_tag="VWZ68_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEU9371585.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMNYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(44440..44679)
                     /gene="dltC"
                     /locus_tag="VWZ68_000506"
     CDS             complement(44440..44679)
                     /gene="dltC"
                     /locus_tag="VWZ68_000506"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEU9371586.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(44693..45937)
                     /gene="dltB"
                     /locus_tag="VWZ68_000507"
     CDS             complement(44693..45937)
                     /gene="dltB"
                     /locus_tag="VWZ68_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEU9371587.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIVIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(45934..47484)
                     /gene="dltA"
                     /locus_tag="VWZ68_000508"
     CDS             complement(45934..47484)
                     /gene="dltA"
                     /locus_tag="VWZ68_000508"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEU9371588.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(47505..47636)
                     /locus_tag="VWZ68_000509"
     CDS             complement(47505..47636)
                     /locus_tag="VWZ68_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEU9371589.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(47950..49128)
                     /locus_tag="VWZ68_000510"
     CDS             complement(47950..49128)
                     /locus_tag="VWZ68_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9371590.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTCINLVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMEIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            complement(49584..50840)
                     /gene="ltrA"
                     /locus_tag="VWZ68_000511"
                     /pseudo
     CDS             complement(49584..50840)
                     /gene="ltrA"
                     /locus_tag="VWZ68_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT        15392 a        11138 c         9222 g        15767 t
ORIGIN      
        1 ctactccccg attagaattc tttttaggtt tagctacatc agtttcttgt tttatattat
       61 ctactttttc aacaatgata tcattactag tagataaatt tgatttaaga acatctttta
      121 tatgttctga tgttacatag aacttaacag tttcaggaat tgcaaatgta tcttttttca
      181 cagaaaactc tgtactttta ttcttaatat gaatttcctt taatgaatct aagacgccac
      241 ttaggaagaa ggacggcaat gagttgatat tattaccaat tgttaaactt tttaattttg
      301 gtaaaccgtt cataacgtgt ttaccaaaat ttttaacatt atctggtaat ataagttctt
      361 ttaattctaa attaccgtaa aaggctaaac gttcaatagt ttctaaacta tttggtaagc
      421 taatttcttc aagtttaatc gcatccgcaa atgcaaaagt accgattttt tctaaacctt
      481 cattcaattc gagttttttc aagtaagaat ttttattaaa cgaatatgat gcaagttctt
      541 ttgtctcttt aggcgtttta taactttcgt catttttttg acttggataa taaattaatt
      601 gagttttatc ttttgaaaac aaaacaccat caactgaggc aaacgattca tttccttctt
      661 caacatcaac atgttttaag ctagtagtga gtctaaatag attacttcct aatgttttaa
      721 ccgattttgg taatgttagt ttctctaaat ttgataaatt agcaaaagcc tcatgtgata
      781 ttaattctaa ttttgaactt gaggaaaagg ttagcttttt caatttttga ctaaaagaaa
      841 atgcacttgt tccaatatat tctagagatg caggcaattc aatctcttct aattcagaaa
      901 aatcaaaagc tctatcttca attttctcca gctgactgcc tttgtcaaaa ataatagttt
      961 tagctttact tccatggaag cctttttttt gtattttttt tatgcttgat gggatagtaa
     1021 tagagctagg atagtagaca attctacctg tttcatctgg ataataacta aaagcttgac
     1081 tagctacttc agtaacggta aatactttat cacctactgt gatttttgta ggaatcgtga
     1141 atggttttcc atcttgacca gcttcaaact ctacaggagt aactccatta cccacttgaa
     1201 cagttcctat gttaccttct acagttagaa ccttatattt gatattattt tgttgaataa
     1261 tacttccaac tttagtctct ttgattactt ccgaactagg agtatctgct aggattggtt
     1321 cattagggac atatgctgct aaaataaccg cagctgtagt taatgataat attgtagttt
     1381 ttttcattta aatttcctta catatttatt ttctaataga tataaaatta taactttgct
     1441 agccgttgtt ataaaaagtt ttattcaatc attatctagt agaatagagt agtacatttt
     1501 ataaattgtc atctctccat aaacacagta tatcattttt aaattttaag tcaaggaaaa
     1561 ttaactgagt aaaaactctc gaaattcaat tcgctatatt atcactcaac ttgaacaaat
     1621 accagaacca caaaaaacag atgtaaagga aaaatatgga cttaaaattt gaaggggttg
     1681 atttagaata caaaaaagct aaaaacaatc ttccagagtc tttctgggaa acctactcag
     1741 catttgcaaa tacaaatggc gggaaaataa ttctcgggat agatgaaaaa aacattgaca
     1801 cctaccaaag agtcaataga ctccctgcga aattatgaag caagtaaaca attaactgat
     1861 acacgattta agcgtcttgt tggtgttcag cgcacgactt ttaaagagat gttagctgta
     1921 ttaaaaacag cttatcaact taaacacgca aaaggtggac gaaaacctaa attaagccta
     1981 gaagaccttc ttatggccac tcttcaatat gtgtgagaat accgcactta tgaagaaatt
     2041 gcggctgatt ttggtatcca cgaaagcaac ttaatccgtc ggagccaatg ggttgaagta
     2101 actcttgttc aaagtggtgt tacgatttca agaactcctc tcagctctga ggacacggta
     2161 atgattgatg cgacggaagt acaaatcaat cgccctaaaa aaacaattag cgaatcattc
     2221 tggtaaaaag aaatttcacg ctatgaaggc tcaagcgatt gtcacaagtc aagggagaat
     2281 tgtttctttg gatatcactg tgaactattg tcatgatatg aagttgttca aaatgagttg
     2341 cagaaatatc agacaagttg gtaaaatctt ggctgacagt ggttatcaag ggctcatgaa
     2401 gatatgtcct caagcacaaa cttcacgtaa atccagcaaa ctcaagccac taacagctga
     2461 agataaagcc tataaccatg cgctatccaa ggagagaagc aaggttgaga acatctttgc
     2521 caaagtaaaa acgtttaaaa tgttttcaac aacctatcga aatcatcgta aacgcttcgg
     2581 attacgaatg aatttgattg ctggtattat caatcatgaa ctaggattct agttttgcag
     2641 gaagtctatt gaaatactaa gcctacacag actgatttca attttaccat tcttcatagt
     2701 caaaaccatc ataatctgga tattgttctg gcgacgttcc aaccgaacgt acgagataag
     2761 cttcttcgtc ctctgtctcg atttctctca gcacttggca ttcaaaacgc cattcatcac
     2821 cgaagtcgaa aataaactta aatttttgtt tgacacttag gctatccaga tagacatttt
     2881 ctgtgtaacg ttcttcaaca tcgtcactaa caaagctaag aaagtaagaa tctgcatgac
     2941 tccactcaat attatccatg aaaaatgcgt gagcatgatc atttgcaaaa tcaaaactcc
     3001 ataaaatcac atctgctagt tccgctaacg tttttgtttt tggaatctat atatgtcggt
     3061 agcaaccttt tttaaatttg acggaaatga tccaagcctc tacagatgct ggcttttcag
     3121 cttctatttc ttgttttact aattttaact gtagcatttg aaaccagata attcttctgt
     3181 ttcacgcgaa acaccctgcg ccaagcaagg tgttcttgtt tttatactca atgaaaatca
     3241 aagagcaaac taggaagcta gctgcaggct gctcaaaaca ctgttttgag gttgtagatg
     3301 gaagctgacg tggtttgaag agattttcga agagtattaa gtcgtataaa tcgtcgaagc
     3361 tgtcgcaatg gtatgccact ggttagctgt agttgctgcg aaatccttgt ctgcgtagaa
     3421 gtcagtaaat ggtaggattt caacttccag ctcgtcgatg cggtcaagct ggccagccag
     3481 ataaacctcg atacggcttt ctgctcgttt gatgcgttgc aagagtccgc ccatacggat
     3541 gtcaactgta tccaaaccaa agaccttgtt ttctttcagc cattggtgac taaagagggc
     3601 atggaagtct tcaatttggc ttctaagttc tggtaattct tgtctggcga tttgttgtaa
     3661 actttcttta tcatccgctt ggtaggcctg acgaatgcgt cgtcccacat ctactttgct
     3721 acttaaaata gcattcaact gggcctgagt ttcaaagaga taagcatagt ttccagcttt
     3781 ttctttaatg ttagcaagcg tctcagcagc ctgagcgaag tgcggtttgt cctgttcagg
     3841 tgtcatgtgt cggtcaagta tcggacagag aacatcctga taaaagacat atcggttggg
     3901 attgatgcca ctgagattgc ctggtaggtc tggtaagagg ttggcaaggt caatctgcat
     3961 aaaatcctca accgttagac cagtattggt cttgaagtgc gcagacaaac tatctaggtc
     4021 atggcgatag ctgagttctg cccagatttg caagcttggt aggatagaga actgggcagt
     4081 ttcaccccca ttgtctcccc aacccgttac gatgacttct ttaatctgat tggcacggca
     4141 ggctttatta gcctcgatag ccactagacg gctaaaatgg ttgtgaggtg taaagccaat
     4201 ccacttccaa gctccccctg caaatgcaag gtcatggcta atcttgtgat gattgcggaa
     4261 attacggttg tatttttcct cgctatcctg ataataatcc cagtaaacca gagtcacacg
     4321 gtctttgaga cggtctaggt agacacgagt ttcctctgga atttccacat cacggtcgta
     4381 ctggccatcc gctgacatga gtttgaagaa catatcactc cacatctggc agtggaaacc
     4441 atatttgtca gcaatatcca gcacgcgctc caagtgttgg cacatgagga gactacgatc
     4501 cacaacaccg ttcaaaatca ggtagcgtcc caaaccaacc aagtgggctt cgtccatccc
     4561 gatattgacc ttgcgagtct tcagtttaga caacgtggca aacatgccat caatcaggtc
     4621 ataaaccttt tcttcgccaa tgagaagaat gtcctctaca tcacggagct cctgcacttc
     4681 cttgacaccc catttgacaa aggccgacaa gtgggccaag gtctggatgc atggtacaaa
     4741 ggtcatgtca aactgttggg cataggcttc gatttcctgc aactcctctg ctgaataagc
     4801 tccacggaaa tagccaaagt aaggctgtcc ttcaatctgg taagtgtctt ccatgtaaag
     4861 ctcaaaggtt gagtagccca tgagagccaa gacctcaatc atctgcttgg cagaagccac
     4921 attcagcacc gcatttcgag aacagtcaac catgtaagcc aaatcttcgt aagctgcttg
     4981 ttcctcaatc tctactttat cagcttctgc tagaactgtt accaacaagg acaaggcacg
     5041 ataaagttgg tgaggtttgc gataggtcaa ttgatagtga ccttcctcac cctggataga
     5101 gatagatgct tggtcagact gagtgacagc cacttccaca tctggtagag aaatgtgacc
     5161 ttttaaaacc tcaatagctt gcgtttgttt gggactaagt cctataaatc ttaccactgc
     5221 ttttcctcct gtagccagtt gacaagagca ccgtagagat tggcatctgc gtgataggtg
     5281 caggcctgga taactggtgc gaccgtgtat tcttcgtagg catcgacaaa gtcttcaaca
     5341 gccttcttaa caccttggat aaaatctgga ttttgactga tagagccacc cagactgatg
     5401 acatctggat cgatgagata ctggatattg agcaagcctt gcgtcaaatt gcggttcatg
     5461 cgctcaatgg cttcttgaca aagagcatta ccagctgcgg cctcttggta aatcttgcga
     5521 ccgtcccaat cagtatgacc agatttttca atcacgtatc gtaccatatt cccagttgat
     5581 gctagttgcg accagttatt aagtttttca gcaggggcaa gggttgtcat gtagccaaat
     5641 tctccaccca gaccgtggcg acctcgatga agtctaccat tgataatcat ggctccgcca
     5701 atccctgtcc caatcacgac acaggctgca ttttcaagct ctggatgagc tagtagttca
     5761 ctgagtccaa cgcagttggc atcattttct aaatggacag gtagctgata agagctaagc
     5821 gcctcatacc aagaaaagcc atggatgtag ggcaccgcac tgaagccatc aatcacacct
     5881 gtctcttgat tgactgcacc tggaacactc atagcaatcc cactgtaatc ctgttctgac
     5941 aagcgttgat ctagccacgc tagtaaatcc tccaagtttt caggcgttga aatacttgtc
     6001 ttatccagta ttttcccatc aggagtcaga ctggcaaact taatcccagt ccctccgata
     6061 tcaatcgttg caatggtcat tgtttttacc ataaaaaggg gcgaatcagc agttagttct
     6121 tactttttcg cccctccttt cttttgatgt ttactttttg aaattaaatt tcttcttttt
     6181 tgatgaattc tgtacgaatc tcttgtggag ccaatagtcc tgaatgaact ggatatggtc
     6241 gctcaagtaa gtcaagaatg gtttgttgat gttctgatat gcgcacattt tcttgactca
     6301 tattatagta acggaggaca tagccttctt cattttccgc cactttaaag gctgttggac
     6361 aaacttgcgg tatgctgaga acagaatggc tcaagaggct accagtcgca accacgcttc
     6421 cttcctgtct agcaagctga aggctggtaa acggtgtctg caaggctttg gcacgacgat
     6481 aggctgagaa gcgttcttgg gcttggtggc attcaatcgc aaattcgact tcaaactcac
     6541 gcaagcattg tgcttctggc gttgggaagt agccccagtc acctagctca cctgatgcac
     6601 gcaaaatggt cacggcaatg gtgttatccc caaggatttc gtattcattc aatcccttgt
     6661 tggatacagt cacccctttt tcatcgtcat acagactgac aaaagcttgt tggtgttgag
     6721 gattttcagg attttcccat gaagcagctg gtttgtttgg tcgtgtcacc acctcataga
     6781 tactttcaga atcattgctt ggacgcgtgt tatgagtctt gaccaagaga cggatacggt
     6841 gatccttggc agtgttagta aagcgagtct tgaagcggat ttgtggattg tcaacaaaga
     6901 caatcaactc agtttccaga ggaatgtttg tcaattcttc tgaccgtcca gcctcacgct
     6961 tcataaactc gatgatacct tgttgctctt cttctagctt ttcatccgca ctgacaggca
     7021 cggtcaattc atgtttgagc aagattttag catagcgatc tgtgttttcc aagacctcgt
     7081 ggcccttaag ctctgcaaag attggctctg ttccttttgg ttggaaatag atatactcgt
     7141 ttccgatgtc accccggtct tcaaagcgga taaagtcttc ataggcttcg tgagttgtct
     7201 tgtcatagac tgtgatgttg tcatccacac tcaccgttac gaatggtgta tcaatcactc
     7261 cgttttggta aataccctca cggtgttctt gttttccttc cagcaattgg aaggttgtcc
     7321 aagaaagcgg cgctaggtga actggaatgg tcacgcgcac ttgtcgagca atacgagctt
     7381 ggcggaactt atcttttggt aaatcgtact caaaattagc tccgaggtct tcgattgtag
     7441 cctctacagg acgaccatcc aagtcctcca cacggtaact tggcaagata agagcagcca
     7501 tctttttgta gccttctgtt gggtgcaatt ccttgaaatc acaagtcgcc acatcaatca
     7561 ctgtgctgac agtatcgacc ttatcatgca agcctgtgtt aatgacagta aagagatagt
     7621 cactttgagc cttatccgta gcaattttac ccttccactc gttgagcaag ttacttttaa
     7681 caaagtttcc tacttggttg accttggcaa aacgcgtttc catctcgcgg tgaacttcgt
     7741 ccacgctaca gccacagata ctatcatgtg gcgcattctg caaaagtgtt ttccaagcat
     7801 aggtcaactg gtccttgtgg ttgtgtccac cagtgataat agtcaagggt tctaccactt
     7861 gctctaggag gttgctattt tcttggaagg cttgttttag gtaaatgcgg gatgaagaag
     7921 tgttggcaag tgtgtaccag ccatctgttt cctgactggt caactcgcct gtaacagttg
     7981 ataagtgttc aggaagcgca ccttctacag cttgaacata ttcatcaaaa gaactatgaa
     8041 caaagattac atccgggaag agttcatttg ccacacgaat ggcttcgctc agatttttct
     8101 gtacaggctg gtggtcacag ccgttcatca tcaaccattg gttggtcgaa gcgtaggcac
     8161 gcacatctga caatttttgt ttccagaagg tcaaggcctc atctttgtca actggaattt
     8221 cattcccgtt actgtaccag ttggcaaaga gaatacctaa aacacgacta ccatccacac
     8281 cctgccagta catttctgaa aactgagacg taaactgctc atcttcaagg acttggttgt
     8341 caaatccaat cggcttcaca ccacgaccaa aggccgccac gtgaatgcct gatttttgaa
     8401 gaatttgagg cgcttgtccc atatttccaa aggtatctgg aaagtagcca atctgggttg
     8461 atttacccca tttggcagct tcttgttgac caatcaaggt attgcggaca ttggcttcac
     8521 tggagatcaa gtagtcatcc tgcaagatgt aaaagggacc aattttaagt ttgccctcgt
     8581 caatgtagcg ttggaccttg tcgcgatttt cagggcgaat ttgtaagtag tcatcaagga
     8641 caatagtttg tccatccaag tggaaactct tgaactcagg gtcattttca aagagatcaa
     8701 agagattgtc aaacaattcc accaactgca tacgatggct ttcaaaaggc aagtaccact
     8761 cacgatccca gtgactatgt gagataatat gtacaacaac attttccatg aagtaaaacc
     8821 tcattctaaa tttaaatttt aacgttttaa atgtaaactt gtgattctga taagaatcgg
     8881 ttgagctaaa gcgagcccct tagcgaatat ccaagtaatc caagaccaac tcacagaaca
     8941 tcatgttagc ccaggagaac cattcacgag agtagagggt cggatcatct acatgaaagc
     9001 tttcgtgcat gacacctgta ccaccatcgc aggcaaccag ctgatccagc aagaattttt
     9061 tctctgcctt atctcttgtt gtcaagcctt ggatagaaag ggcgattggc cagatatagc
     9121 gatagaaggt atgagaactg ccgagaccgc ttgcgtattc tccttggtag aagtatggat
     9181 tttcagagct caaaatggta cgacgagtag cttgatacac ttcatcatcg accgaacagt
     9241 agcccagata gggcgcagct agtagacttg gtacatttgg atcatccatg atgctggcat
     9301 ttcctaggcc atccacttca aaagcgtaaa tcttttcgcc cttgctgttg gtggtgtaag
     9361 cgtagttttt gattccttct tggatttcat cctgaagacg cttggcatca gcaataacac
     9421 tctggctatc agctaggttt aatgctgcga agatttcttg cacataaccc aagactacta
     9481 cagcaaacat atttgacgga atcaagtaac tatactggca acagtcatca ctcggacgaa
     9541 aggctgacca agtcatacct gtcactgcaa agtcaggtcc aaagccatca tttaccaagg
     9601 tgtcttcctt acggtccgta tctcggacaa aacgataagg agagttcttg tggtcttgtt
     9661 ccaccgtcca cagatggaga atttccttag tcgctgcgac aaaaatctca tcaaactgac
     9721 tagtctcgcc agtctctttc cagaggagat aagccaactg caaaggatag caaagcgaat
     9781 ccacctcata cttgcgctcc cagatccagc cgttaaggtc tgtgtggtca gtctcgtggt
     9841 gccctttcca gttctcctca atgttgaagg agttagcata gggatccttg agtaccaagg
     9901 tcatctgacg tttgaccaaa cctgcaatgg tctgacgcag gagggcatct cttttagcta
     9961 catgaaggta gggtctgagt tgggctgtcg aatctcgaag ccacatggca ggaatatccc
    10021 cagtcaagac aaaagttgaa ccatcttcta agatttcaac cgtattgtcc aaggtatcgg
    10081 tgtagcaacg ctcgaaaaca tccacccact ctggatagtc cttagcccgc tctgctactt
    10141 catctagcca ctctctgaca atttctttcg aataaaccat tttaaatttt acctctttca
    10201 aacaagtttc atgttcagta tatagctttt gagacagaaa atacatacac aaatgatagt
    10261 catttttcta caaaatagtt atttttgaaa ctccttttct aaaggccctc tttttctgat
    10321 ataatgtaga aaaacagcta aaggaaagac tatgaaacca ctacttgaaa ccatcgatac
    10381 ccgctttgga actaccaaca agcatgcctt ttctcgggga aataccctgc catacacagg
    10441 cgtgcctttt gggatgaatt actttgtgcc ccagaccagt gaccaggatg gatcttggtt
    10501 ttttgatcca catctgccta tctttcaggg gattcgatta actcaccagc ccagtccttg
    10561 gattggggac tactcttggc tccttctgac acctgtcacc agtcaactgg ggggagacag
    10621 cctctttcac cgccagtctt cttatgatat agataaagct tgcttccagc ctcactattt
    10681 gaagctcttt tctctgcgtt atcagattga aacccagctc acaccgactt gctatggtgc
    10741 ttctattcgt ttgaatcaaa agcaaggcaa agccctctcc ctctatcttc acgcagcaga
    10801 tgaactgaca gtagagcaag tagataagcg gactcttgcc ctgcgacaag aaggtaaaac
    10861 tgaaactaac aaaaattcgc taacgatgtt cactgccctg caaatgaaca cggatattct
    10921 tgctatcagc caagaagctg gagactggcg aattgactta gcaagtagtc aaaccgagat
    10981 gcaactagcc acttctttca tctctccttc tcaagctcta atcaatctac ctcaagaaga
    11041 ttttgatagc tgtaaatcaa gtgcccaagt ggattgggaa aatctcctcc atcgttttga
    11101 cattatagag acaggagagg ctgaccgaac cttctttgac cactgcctct acagactctt
    11161 cctcttccca cagacttttt atgagattaa tgaatcaggg caagccatcc acatggatct
    11221 ggctactggt actgtcaagc ctggtgtcct ctttagcaac aatggtttct gggatacctt
    11281 ccgcaccacc ttccccctct ttgcccttat cataccggag cactatcaac gctttttaga
    11341 aggtttcctc aatagctacc gcgatactgg tttccttcca aaatggctgg ctccagatga
    11401 acggggtatg atgccaggta cacttttaga cggtattatc gcagatagcg cctgcaagga
    11461 catgaccccc gacctagaag gagaactctt ccaagccatg ctcgaaacag ccagcaaagc
    11521 cgaccctctc ggcatcaatg gccgccacgg actagcccaa taccaagaac taggttacct
    11581 ctctaccgac caccacgaaa gtgttagcca tactctagac tatgcctata gtgacttttg
    11641 tatcgccagc tgtgccaaaa aactagagaa catagaaatc gctgaaacct acaaggctgc
    11701 ttcacaaaat taccgccagc tatttgacgc tgagacaggt tacatgcgag cacgagacaa
    11761 tcaaggaaac tttcaccctg acttctctcc ttatagttgg gggcgagact acgctgaatg
    11821 ctctgccatt caagctactt taggcgttct ccacgacatc cctggcttaa tccaactgat
    11881 gggtggaaaa gaaaccttta gcaactatct tttgaaagcc tgtcaagatg ctcccctctt
    11941 tgaaacaaca ggctatggtt acgaaattca cgaaatgagc gagatggcta ctgctccttt
    12001 tggacaaata gccatttcca accagcctag tttccacatt ccttatctct tccgttacag
    12061 cgattaccct gactacactg cccttcttat caagacgctc cgtcagaaag cttttcaccc
    12121 aagttgggaa gcctatcctg gagatgaaga caatggtagt ctctctgctt ggtacatctg
    12181 gtcagctctc ggattttatc caacctgtcc aggaaaacca agctatgacc tcggaatccc
    12241 tctctttgac catctacgag tctacctcgc taaagaagat aaatggctgg atatccatac
    12301 taaacaaaac cacaaccatt ttaactttgt caaagaatgc cgactggaca aaacactcgt
    12361 atcaactatt caacaccaag acctcttaaa agctgaacaa ctaactttca ccctcagctg
    12421 gttaccaagt cactaataac caaaagaacc tttgcatcgc gcaaaggttc ttcttttatg
    12481 aaacttggac ttgaagttga tccacaagct gaccatccac cgttaggttc agatagaaat
    12541 ccaaggtttt atctcctgcg aaatacaagg ttggtagcgt cagacttttt tcagtctcac
    12601 cagtttgaaa cgcaaggact tgaatctcat cctgataggc gacaccatgg acacctgtcc
    12661 ccggttgaat cgaaatctta gcttctaaag gaccactaca ttctctgcgc ttaactgtaa
    12721 aataggcatt ttctcccttt gccacagcta ggcttttttc tgcaaatgct agttcctgaa
    12781 caacttcttt ttttgataat ccaggagttt tataaaggga aatcttggtc aacaaaggca
    12841 aagcctgtga ttctgtaatg actacacgta tcttctgtgc ctcaacaact gctcctcgta
    12901 agagacgttt gtaaccaaca gtatgacccg aaccaaactc ctgccagaca ccatccacct
    12961 ctacttgcac atgaaaagca gcgattcgtt gccctagctt caaatcttct cttaactcaa
    13021 ttacatcaaa agttttagga gaacctaagt cgagttctaa ctggatgggc aagtctgcat
    13081 cgcttgccca agagctggtc tcaaggccgt ctgtcaaatg gcgacaagca aagtctgcgg
    13141 aaagagctgg accagatacc tcagctccca gagccaaatc ttctttatag agctcattgc
    13201 gataggtcgc aaattcataa agtcgttcaa tatcctttgc atcaaagagc ccagcttgat
    13261 tcggcggaat attaagcaag agtggagttc ctcgccctac tgagtgaaag tagatttcga
    13321 ccaactcctc gagagactta ggatcctgat cctcatggta gaaccagcct ggacggatgg
    13381 aaacatctgc ctctccgatt gaaaaaatcg tgcccgaggg atccccgtgc tgaagatagt
    13441 tcagctctgc ttctgttcct agtttatcag gattcacctt ttgccacagt ggatcacctg
    13501 cataccctcg ttcattgcca atccagcgga tactggtgcc ttctgttgaa aaaatcaagc
    13561 aatcgccctg caggtcacga atggtttcaa accatttttc aaattcataa ttaacctttt
    13621 gcgcgccctc tcctctggca ccatccatcc aaacctcagc gaacttacca gcattcccat
    13681 agttaggatt tgataagatt tccttcaact gagccagata ataggcattg tagtccgctt
    13741 ctcggtccac atgatagagg ggactatggg catcccacgg tgacaggtag acccccatat
    13801 ccatatcaaa ctctgtggca gcttgggata cttcaaggag caagtcgccc tttcctctcc
    13861 tccaaggact gaccttaacc gaataatctg tgtgagctgt cggataaagg acaaagccat
    13921 cgtggtgctt gaccaccaaa atcaactttt tgaagcccgt ttccttgagc acacgaaccc
    13981 actcacgcgc atccaactga ctcgggttaa agcgctcagg atcctcctgt ccagtccccc
    14041 attcttggtc ataaaaggta ttaggaccga agtggataaa agctgctagt tcatctccca
    14101 gataagctag ctgagtctga cttggtaacg gtccatgcgg tttgattttc ttcatcgtta
    14161 tatatctcct tctttagcaa cttctcttat tcacaaagtt atccacaggt tgtggataat
    14221 aaaccatgat ctaacagtca gctctttcca actccaactg gtaggctcag gatttttctc
    14281 ctcaatattc cctcttcaaa cagctctgtc atatggttct gctaacacct ctcagaatgc
    14341 tactctccat aattattctc aggcttcttt caggtcattg tgtgaagacc attcactatc
    14401 cagacttttc cacagattgt gaataagtga ttattctaaa ctatcacctc gtcgactata
    14461 acaaaaaata aaaagagggt caataagata attatctctt cctaaatact cagaaaagat
    14521 tctataattt gtacaattga acaagaaatg cttctccaaa atctatcttc aaaagaatgt
    14581 tgcatctttt tatcctttca cacaaacatt tctctttata cagatccaag tgataaccag
    14641 atgataattg gacacttttt gatcatttgt atattttttg aaaaattttt taaaaaaatt
    14701 ttatatcctt tttatagaag tttatgcatt tgtatctatg tattctatcc tatgttatgt
    14761 ataataacat aaaattgtgc taaacatcat aatttatatt attttccgag aaattatagc
    14821 cattgacatt acctaggaat tgcgttataa catacatgta agcggtaccc aaaatggtgc
    14881 caagtcaaaa tttttaagga ggaaaataca tgtcttcaca tccaattcag gtcttctcag
    14941 aaattgggaa actgaaaaaa gttatgttgc accgtccagg caaggagtta gaaaacttgt
    15001 tgccggacta tcttgaaagg cttctttttg atgatattcc tttcttggaa gatgctcaaa
    15061 aagaacatga tgcatttgcc caagctcttc gcgatgaagg aattgaggtt ctctacctag
    15121 aacaactcgc tgctgaatca ttgacctctc cagaaatccg cgatcaattt atcgaggaat
    15181 acttagacga agccaacatc cgtgatcgtc aaaccaaggt tgctattcgt gaattgcttc
    15241 acggcatcaa ggacaaccaa gaattggttg aaaaaacaat ggctgggatt caaaaagttg
    15301 aattgccaga aattcctgac gaagctaaag atctaactga cttagttgaa tcagagtatc
    15361 catttgcaat tgacccgatg ccaaacctct atttcactcg cgacccattt gcaacaattg
    15421 gaaacgccgt atcgcttaac cacatgtttg cagacactcg taaccgtgaa acactctacg
    15481 gtaagtatat cttcaaatac cacccaatct atggcggaaa agtggatttg gtctacaacc
    15541 gtgaagaaga tacgcgtatc gaaggtggag acgagttagt tctttctaaa gacgtccttg
    15601 cagtaggtat ctctcaacgt acagacgcag cttctatcga aaaacttttg gtcaacatct
    15661 tcaagaaaaa tgttggcttc aagaaagttt tggcctttga atttgctaac aaccgtaaat
    15721 tcatgcactt ggatactgtc ttcactatgg tagactatga caagttcact attcacccag
    15781 aaatcgaagg cgaccttcac gtttactcag ttacttacga aaacgaaaaa cttaaaatcg
    15841 ttgaagagaa aggtgactta gctgaacttc ttgctcaaaa ccttggtgta gaaaaagttc
    15901 atttgattcg ttgcggtggt ggcaatatcg tagcagctgc gcgtgaacaa tggaacgacg
    15961 gttctaacac tttgaccatc gcacctggtg tggtagttgt ttatgaccgc aataccgtga
    16021 ccaataagat tttggaagaa tacgggcttc gcttgattaa gattcgcgga agtgaattgg
    16081 ttcggggccg tggtggacct cgttgtatgt ctatgccatt tgaacgtgaa gaagtgtaat
    16141 cgctgttcga tattcgtcaa tagaaaatgt aaaaaataga aagaggaaat aataaaatga
    16201 caaattcagt attccaagga cgcagcttct tagcagaaaa agactttacc cgtgcagagt
    16261 tagaatacct tattggtctt tcagctcact tgaaagattt gaaaaaacgc aatattcaac
    16321 accactacct tgctggcaag aatatcgctc tcctatttga aaaaacatct actcgtactc
    16381 gtgcagcctt tacaactgcg gctatcgacc ttggtgctca cccagaatac ctcggagcaa
    16441 atgatattca gttgggtaaa aaagaatcta ctgaagatac tgctaaagta ttgggacgta
    16501 tgtttgacgg gattgaattc cgcggattca gccaacgtat ggttgaagaa ttggcagaat
    16561 tctcaggcgt tccagtatgg aacggtctaa ctgacgaatg gcacccaact caaatgctcg
    16621 ctgactactt gactgttcaa gaaaacttcg gtcgcttgga aggcttgaca ttggtatact
    16681 gtggtgatgg acgtaacaac gttgccaaca gcttgctcgt aacaggtgct atccttggtg
    16741 tcaatgttca catcttctca ccaaaagaac tcttcccaga aaaagaaatc gttgaattgg
    16801 cagaaggatt tgctaaagaa agtggcgcac atgttctcat cactgaagat gctgatgaag
    16861 cagttaaaga tgcagacgtt ctttacacag acgtttgggt atcaatgggt gaagaagaca
    16921 aattcgcaga acgtgtagct cttcttaaac cttaccaagt caatatggac ttagttaaaa
    16981 aagcaggcaa tgaaaacttg atcttcctac actgcttgcc agcattccac gatactcaca
    17041 ctgtttatgg taaagacgtt gctgaaaaat ttggtgtaga agaaatggaa gtaacagacg
    17101 aagtcttccg cagcaagtac gctcgccact tcgatcaagc agaaaaccgt atgcacacta
    17161 tcaaagctgt tatggctgct acacttggta acctttatat tcctaaagta taattttaga
    17221 taataaaccg tctaccaaca gctatgaggg ctgcgactaa tagctttagt ccggtcctct
    17281 tttatgtaat ggtaatctat tatttcttat aaaatatgtg aaaaatcatt aaattgaaat
    17341 ctaaacgcat tctattgagt gtgataaagg agaatttatg gcaaatcgta aaattgtagt
    17401 agctttggga ggaaatgcga ttctttcttc tgacccatca gcaaaggctc aacaagaagc
    17461 tttagttgaa acagctaagc atcttgtaaa attgattaaa aatggagatg atctgattat
    17521 cactcacggt aatggacctc aagttgggaa tctcttgctc caacatttgg catcagactc
    17581 tgaaaagaac cctgccttcc cactcgactc acttgtcgct atgacagaag gtagcatcgg
    17641 tttctggttg aaaaatgctt tgcaaaatgc tctcttggat gaaggcatcg aaaaaaatgt
    17701 tgcctctgtt gtaacgcaag ttgtcgtaga taaaaatgat ccagcttttg ttaacttgag
    17761 taaaccaatc ggtcctttct attcagaaga agaagcaaaa gcagaagccg aaaaaagcgg
    17821 agcgactttc aaggaagatg ctggccgtgg ctggcgtaag gtcgttgcct caccaaaacc
    17881 tgttgacatc aaagaaattg aaaccatccg tactctttta aataatggtc aagtcgtcgt
    17941 agctgcaggt ggtggcggta ttcccgtcgt caaagaaaac aatggacatt tgactggtgt
    18001 cgaagcggtt attgataaag acttcgcttc ccaacgtttg gcagaattgg ttgatgcaga
    18061 cctcttcatc gttttgacag gtgtagatta tgtatttgtt aactacaaca agccaaacca
    18121 ggaaaaattg gaacatgtga atgttgccca gctggaagaa tatatcaaac aagatcagtt
    18181 tgcaccaggt agcatgcttc caaaagtaga agcagctatc gcttttgtca atggtcgtcc
    18241 agaaggaaaa gcagttatta cttcccttga aaatctaggc gccttgattg aatctgaaag
    18301 tggaacaatt attgaaaaag gataagttgt tttactaata agatgtattc tatttctagt
    18361 atctttatat caaattagaa attattcttg aaaacatgta caatatttca aaagatatta
    18421 gttttttaga ctttaatatg gtaaaacaaa tataaataga aagcgttttc ttaaatgttt
    18481 atttaagaaa gtagttggtt ttttacactt tgttagacat caggaggaaa aacaaatgag
    18541 tgaaaaagct aaaaaagggt ttaagatgcc ttcatcttac accgtattat tgataatcat
    18601 tgctattatg gcagtactaa cttggtttat ccctgcgggg gcctttatag aaggtattta
    18661 cgagactcag cctcaaaatc cacaagggat ttgggatgtc ctcatggcac caattcgggc
    18721 tatgctaggt actcatccag aggaaggttc gctcattaaa gaaacgagcg cagcgattga
    18781 tgtagccttc ttcatcctta tggttggtgg tttccttggc attgtcaaca aaactggtgc
    18841 tcttgacgta gggattgcct ctatcgtgaa gaagtataag ggccgcgaaa aaatgttaat
    18901 tttggtacta atgcctttgt ttgccctcgg tggtacaact tatggtatgg gtgaagaaac
    18961 aatggccttc tatccactcc ttgtgccagt tatgatggcc gttggttttg atagcctgac
    19021 tggtgttgca attattttgc tcggttctca aatcggctgt ttggcatcta ctctgaatcc
    19081 atttgcgaca ggtattgctt cagcgactgc gggagttggt acaggggacg gtatcgtact
    19141 tcgtctgatc ttctgggtta ccttgactgc tcttagtact tggtttgttt accgttatgc
    19201 ggataagatt caaaaagatc cgactaagtc actggtttat agtactcgca aagaagattt
    19261 gaaacacttt aacgtagaag aatcttcatc tgtagaatct acacttagca gcaaacaaaa
    19321 atcagttctc ttcttatttg tgttgacatt catcttgatg gtattgagct tcattccatg
    19381 gacagacctt ggcgttacca tttttgatga ctttaatgct tggttgactg gtcttccagt
    19441 tattggtaat attgtcggtt catctacttc tgcactaggt acttggtact tcccagaagg
    19501 cgcaatgctc tttgccttta tgggtatcct gattggtgtt atttatggtc ttaaagaaga
    19561 taagattatc tcttccttca tgaatggtgc tgctgacttg ctcagtgttg ccttgatcgt
    19621 agcgattgct cgtggtattc aagttatcat gaacgacggt atgattaccg atacaatcct
    19681 caactggggt aaagaaggct tgagcggtct atcttcacaa gtctttatcg ttgtaactta
    19741 tatcttctat ctacctatgt cattcttgat cccatcttca tctggtcttg ccagcgcaac
    19801 tatgggtatc atggctccac ttggagaatt tgtaaatgtc cgtcctagct tgattatcac
    19861 tgcttatcaa tctgcttcag gtgtcttgaa cttgattgca ccaacatctg gtattgtgat
    19921 gggagctctt gcacttggac gtatcaacat tggtacttgg tggaaattca tgggcaaact
    19981 cgtagtcgct attattgtag tgaccatcgc ccttcttctc cttggaacct tccttccatt
    20041 cctataaaat agtgagtgag gtgattccat gaaaatagat ataacaaatc aagttaaaga
    20101 tgaatttctt atatcattaa aaaccttgat ttcctatcct tcagtactca atgaaggaga
    20161 aaatggaaca ccttttggac aagcaatcca agatgtccta gaaaaaactt tagagatttg
    20221 tcgagacata ggtttcacta cctatcttga ccctaaaggt tattacggat atgcagaaat
    20281 cggtcaggga gcagagcttc tggccattct ctgtcatttg gatgttgttc catcaggtga
    20341 tgaagcagat tggcagacac cgccatttga agcaactatc aaagacggct gggtattcgg
    20401 acgtggtgtc caagatgata aaggcccttc gctcgcagct ctctatgcag taaaaagctt
    20461 gctggaccaa ggtattcagt tcaaaaagcg cgtacgcttt atctttggta ccgatgagga
    20521 aaacctctgg cgctgcatgg cacgctacaa taccatcgaa gaacaggcca gtatgggctt
    20581 tgcacctgac tcatcttttc ctctgaccta tgctgaaaaa gggcttctac aggtcaaact
    20641 tcatggcccg ggatcggatc aactagagct tgaagtagga ggcgccttta acgttgtacc
    20701 agacaaggcc aactaccaag gtcttctcta tgaacaggtt tgtaacggtc tcaaagaagc
    20761 tggttatgat taccaaacca ctgaacaaac cgtaacggtt ctcggagtgc caaagcatgc
    20821 taaggatgct agtcaaggta tcaatgctgt catccgacta gctaccattc ttgctcctct
    20881 ccaagaacac cctgctctca gttttcttgc aacacaagca ggtcaagacg gcacaggaag
    20941 acaaatcttt ggtgatatag cagatgaacc ttctggtcac ctatccttta atgtcgcagg
    21001 tctcatgatc aatcatgaac gttctgaaat ccgtattgac attcggactc ctgtcttagc
    21061 tgacaaggaa gaactagtag agttgcttac aagatgtgca caaaactacc aactccgcta
    21121 cgaagagttt gactatctag cgcctctata cgtcgcaaaa gacagtaaac tcgttagcac
    21181 actgatgcaa atctaccaag aaaagactgg cgataacagt cctgctattt catccggtgg
    21241 tgccactttt gctcgcacca tgccaaattg tgtagccttc ggcgccttat tcccaggagc
    21301 gaagcagaca gaacatcagg caaatgaatg tgccgttcta gaagatttgt accgtgctat
    21361 ggatatttat gccgaagccg tctatcgact tgcaacttaa tcaggcaact gtttctacaa
    21421 aaaaaaatcg accgattaat gaactgcacc ccaaaagtta gacagaataa atctaacttt
    21481 tggggtgttt tattatgaaa ttgaattatg aagataaagt tcagatctat gaactaagaa
    21541 agcaaggaca aagcttcaaa cagctttcaa aaagatttat gtggatgttt ctggtttaaa
    21601 gtcatctgaa tctttgagat gagctttata aatcgctttt ttcagtgttt gcactggtgt
    21661 ttcgataaac tcaaactttt tagccgtggt attgcctgat tttatagtat attgaaacta
    21721 gaatagtaca cctctacttc taaaacattt ttagaaatcg atttgtcctg ttcttatttc
    21781 attttactat atttgagcca cttcgtcttt aacggcttta ttcataagct cttgtaattt
    21841 ttctttacta tcaattactt ctgattttcc gttgtaattt attgtaatag gttttaactt
    21901 acctaatttc tcgacacgct cattaatttg atcttttttg aaggctgcat atgtttttcc
    21961 taagattttt tcgaaaatat atttatcaga tagcggtttg ccttcttctt cagcttggtt
    22021 tttgtattga tttgaaacat aaggaacaaa tccttcatag taacctaatg ctcccataag
    22081 ttcaaaagct tgttttctaa ttcaaaccat tgcaactcag atttcagctt ttcagataaa
    22141 tcctgctcat ccaaataatg acttaaaatt agtgctgaac tcgtttctgt atcctgtaca
    22201 ggctgatcac ccataccatc aaaaaataaa ctcgttccta gcaagaccga acaagctcct
    22261 attgcatatg gcctcaaaga aaaacgctgc tttctctcaa attgaaattc tttcatccca
    22321 tctcccatca ttcattatta ctgtatattt tgtatatcag aaatagtttg tattcacaaa
    22381 tctttctagt tattccctta tcattcctaa ttaagggaga taacatacaa taatttttag
    22441 ttaaatgtat atcgatgttt tttgtttttc ttaataaacg caatacaaaa agagcctgtt
    22501 gccaagctct ttgtactcaa tgaaaatcaa agagcaaact aggaaactag ccacaggttg
    22561 ctcaaaacac cgttttgagg tagtagataa gactgacgaa gtcagctcaa aacactgttt
    22621 tgaggttgca gatagaactg acgaagtcag taacatctat acggcaaggc gacgctgacg
    22681 tggtttgaag agattttcga agagtattag tctattattt cttctcagcg cgaagggctg
    22741 acaagatttg tgttcggata tcatccacac catttggagt atttggtaaa aagatggttt
    22801 gatttccttt agaggcaaag gtattcaagg tatccaaata ctggttggtc aagaggatag
    22861 acatgatttg ttcttctgtc atgccaacat tggcttcctt gagttcggtg atagactctg
    22921 ccaatccatc cacaatcgcc ttacgttgtt gggcaatccc cacaccatga aggcggtctt
    22981 tttctgcttc ggcttcagct gcagtgacaa ttttaatctt gtcagcttcc gccaattctt
    23041 gtgctgcgac ccgcttacgt tgcgccgcat tgatttcatt catggattgc ttaacttctg
    23101 catctggttc gaccttggta atcaaggttt tcacgataat gtagccgtaa gtggtcattt
    23161 cttctgctac ttggtgttga acttcaaggg caatctcatc ttttttctca aacaattcat
    23221 ccaaggttaa ttttggaaca gaagagcgaa gagcatcttc gatataagat ttaatctgag
    23281 attctggacg tatgagttta tagtaagcat ctgtcacgct ctgctcgttg acacggtact
    23341 gagtcgctac attcatcata acgaacacat tgtccttggt cttagtctca accacaatat
    23401 cactttgcaa caagcgcaac tgaatccgtg ctgcaatcga gtcaatccca aaaggcaagc
    23461 gaatatgaat accgctatta gcaacctttt ggtatttccc aaagcgttca ataatcgcca
    23521 ccgactgctg acgaaccaca taaactgtac tcagtgtgac tatcaccaat aggagcacac
    23581 aaacaatcag aaaaatcatg aaaaatattg ccataatgga acctccacaa gtatttttct
    23641 agtattatag cacatttaaa gaaggctgtg ccgtttttac tgcgattttt cctgaaatgt
    23701 caataattag aggtgaattg tcctattgtc gtccaatctc ttgctaaaat aactctttat
    23761 aaaaggcaat cgtttcttct aaggttggca taaatggatt tcctggtgcg caggcatcaa
    23821 tcaaggcatt cttagaaagg tattcaaagt cgaaatcttt ttcttcaata ccaagttcag
    23881 tcagtttctt aggaatacct actgtctcag aaagcttctc aatctcagca atcgcataat
    23941 cggcacattc ttgatctgat ttaccttcta catgaagtcc caaggctttg gcaacattgc
    24001 ggaaagcttc tggtacacgt ttagcatttt cacgttctat aactggtagc aacatggcac
    24061 agcacacgcc atgtggcaaa ttatatactg caccgagttg gtgagccatt gagtgaacat
    24121 agccaagacc agcattatta aagctcatac caccaaggaa gatggcattg accatacctt
    24181 cacgcgcttc aatatcatgt ccattttcta cagcacgagg aagatattcc ttgataagct
    24241 caatagcacc aatagacagt ttcttggtta catcataagc accaggtgtt accaaagctt
    24301 caacagcatg agtcagagca tccataccag tagcagcagt caggccttta ggtttggaaa
    24361 gcatgagttc agggtcatta acagagataa gagcaaggct attcttgtca accattacca
    24421 tcttaacctt gcgttcttca tcagtaatca catagttaat ggtaatttct gctgatgtac
    24481 ctgccgttgt attgatagcc acaactggca agcctttttt agcagactta tgaagccctt
    24541 cataatcctg tggttttcca ccatttgtag ccatgataga aatacaacta gctgcatcct
    24601 gtggagaacc cccgccaaga ctgatgataa agtcacagcc atgttcttgc aaagcagcta
    24661 ccccatctgt gacattttta caagtagggt ttggctctac atcgctaaag atgacatatt
    24721 cgattccttc tgtatccagt ggttttaaag tcttaggtaa aatatcactg ccttcgatgt
    24781 acttatctgt caccaaaagt gcctttttat agccaagttc cttgatataa ggacccactt
    24841 catttacaac accttttcca ataaggttga ctgccggaac ataaaatata gccatataat
    24901 tttcctcctg cgcctccgcg ctatctattt aacatcatta tattactttt tgtattcgtt
    24961 ttcaattatt tgtgaattgt ttaacaaatc tttttaaaag gataggaggg acgtaagttc
    25021 acctcctata taaacaagtt ttatttatgt agtggcccca acaactgaca tgcacgatag
    25081 tctgctgatt ctagatcttc tgttccaaat aaggaccaat ttttaggtct aaagatatct
    25141 tcctcaggta cattatgcat attgacagga attctcaaca tagaagccaa ggtaatcaag
    25201 tctgctccaa tgtgtccata tgttatggct ccgtgattag ctccccaatt attcatgacg
    25261 tcatagacag acttgaaagc accttttcct gtcaaacgtg gagcaaacca agtagttggc
    25321 catcctggat ctgtacgatt atctaaagta tggtgaacat cttcaggaag ttcaagtgtg
    25381 taaccttctg caatttgtag cactggacca acccctttta gaagattgag acgtaccatt
    25441 gttactggca tatccccctt cgtcaagaaa cgagttgaga atcctcctcc acggaagtat
    25501 tcgcggtttg ctggtgggaa gtctgtattt tcaagcatag cctgcacttc actttcttcc
    25561 aactcccaga atggtttcat aataggtttg ccatctcgag tagcttgacc tgtaccatcc
    25621 aatgtacaag aaccagagtt gattagatgt aagaagccag ctgcagcacg accctctaaa
    25681 gtatgtcccg ttacacgttt aacagcctct gggctccaat aagtacgcac atcagcaaag
    25741 atttgtggag tatttgttaa tagataatta aagagcatag acacaccatt tagtgaatca
    25801 ttctctgtcg caaatacaaa tggttttcga ataccattcc agtcaaactg agtattgagg
    25861 aaagtttcca taaagtcccc atttggaaaa tggtctgtcc actgacgttg accttggaaa
    25921 ccagctacta aagcatggtg accaaccgct tcttcctcaa aaccaagttc agcaagtctt
    25981 gggttaccaa ccattaagtc acgtccaatc atgaacatct taataacaaa ttcccattgt
    26041 ctatcttttt cttcacggct taaaacaagg tcttcacggt tatggtcgaa tccttctttt
    26101 acgttttctt tcacccattt gagcgcacgt tcgaactctt cagggtcgta aataccacgg
    26161 tccatacggc gcgtgaactc cgtcatatct accgattcat ttcgcattcc taagtattct
    26221 tggaagaaat ccggatttac aatagaacca ccaatcccca tcgaaacact acccattgat
    26281 aggtaagcag tgtctctcat caagccagtt gcaagagctg cacgcgcata gcgtaaaagt
    26341 ttttctttga catcttctgg aatatctgtg tcactagctt cctgaacatc tcttccataa
    26401 atcccaaagg ctggaatccc tttttgagca tgtgaagcta gtacagctgc aagatagaca
    26461 gctcctgggc gttctgtccc attaaatccc caaatagcat gaggaatatc tggagacata
    26521 tccatagttt cactaccata acaccagcat ggtgtaactg taattgttgc gcaaacattt
    26581 gattttttaa acaactcatg ggaagctgca gcctctggta cacggccaat agtagatgga
    26641 gaaatcacgc attccacagg ttccccatct ggatatttca atgtgcttga aatcaaatct
    26701 gccacacttt tagccatgtt cattgtttgc acttcaagtg attcgcgtac accttgacga
    26761 cgaccatcaa tagtcggacg aatcccaata cgtggatgtt gaatcatact attttcctct
    26821 tatttttctg tttctttcat actaccatct ccattatatt tacggtagcc tgggtgataa
    26881 tttttaaaat tacttataag tataaacctc tacctctgct aaacttaaag gaattcctgc
    26941 gcttctcaaa gaaattctaa ccttttttcc cttcagtcct tttaagtcta tggatagatt
    27001 attgctttct aaactgtcaa tatgttgtgt aaaaacttca taatcatttg aatcatatat
    27061 aataatatca aaatttgata atctctgaat ttcagcatct gttctattat aaataattaa
    27121 cttttctaat tcttcggttt gtgctaaatc tatctcccac catgaaggag aatcttcttt
    27181 ggtatgagtc actgaatgat gaccataatc tccgttttta tttccatcaa ctgctagacg
    27241 agaaaaacca ttgtaatccg ttgaactctg tcgagtttct tttgttaatg caatattaga
    27301 aagtttcttc ggagttctct ttgaaccata gacttcaact tccgctaaac ttaacggaat
    27361 agctgctgat tttaattcta ttttgactag cttagcccct acagaaggta cttttaaaga
    27421 taacaaacca tcaactactt tatcaaaatg tcttctaaaa acttcttctc ctgatgaaga
    27481 tagaaaaata acatcaaaat tagataaacg ctgaggttcg gcatctgttc tattataaat
    27541 atcaacttta gaaaccgtaa actcttctcc cagatcgacc tgccaccaag cgttagaatc
    27601 tgccttagta tgagtcaccg aatgatgtcc gtaatctcca tctttattac catcaactgc
    27661 taaagcagct acaccctcat aattggttga actttgagta gctaccttat ttgtagagac
    27721 tactttatct tctgttattt tatctatatc ctcttcagat tgcttaccat ctgattctct
    27781 aaaaacctct acttctgcta aactcaaagg cactccactc gttagtaatt taactttaat
    27841 ataccttgct cctttttctt tgaaatctag actaacagat tcacccgaca aattattaac
    27901 atgtttctta gcaacttcgt ttctattatt gtcatataga atcacatcaa aattagatag
    27961 acgttgagtc tcagcatctg tgcgattata aattttaaca agcccaactt tatccatttt
    28021 tttcaaatcg acttcccacc aagagggatt atctgcccta gtgtgtgtta ccgaaccaga
    28081 gttaaaatta ccatttctgt taccatccac agctctatta gggtctccat tgtaatctac
    28141 agaactttgt gttgttggtt ttgcatatgc tatattcaaa ttaccatcat taaatttatc
    28201 tggtgttggg aaagagactg gacctgtccc ctcagtattt atagacatct ctaccattcc
    28261 attatgatta accgtaatgg tataaacatg ggtattctca tcccaatttt ctgtataagt
    28321 ataatgattt ttatcgccac ttatatttat ctgaggttta tgaccagtat gcccttttaa
    28381 tgtaagtgtt gttgtcctaa agtcattatc tacaggattg atggaataat ttttgcttat
    28441 ccagttcgct aactctaatt cttctttctt ccaacttttt gatgcatcaa aatttcctga
    28501 taatgcccac atagctgtct tatctgtcct gtaattattc aataaaatat gtaaattatt
    28561 tggattttct ttaacaacag cgtaagtatg tggcgtcaaa tctaacgata acgactttgt
    28621 attattagta tacataggca acattacttg ctgattttta ttgatattag cattactatt
    28681 ataaatatac caggaattac ctacacgctg agcataccca tctccttcat aaagttttgg
    28741 ataaagcgag tttaaatagt tgactttact agacaattcc tcactatttt tagtcaaaat
    28801 ttttgcatta gggaatatag atgaaatctt ttccttatca attttctcat gtattacagg
    28861 aagaatatga tatctcccat tattatataa aggcattgtt tcatcattcg aataaagtcc
    28921 ttgataaaat ccgtttaatg aactaatcct accttctcca ttccaaaata cagcttttgt
    28981 tctatttaca acttcttcct tacttggagc tggattttgt atagcatgtc taaagaaagg
    29041 aataatacct ttagtaaatg ctggagttgg tacatcattt gtcataaatg tatacgcggc
    29101 acattcgaaa ttataaactg tgcctccccc agtatataca ttcatcattt ccatagcaat
    29161 cattgattct ggttccgatg cataggatct catatcccta gctcttccag tttcaaatgt
    29221 gtttgtataa tgtttttccc accatttcca tgtatctgtt gatgagcccc agttatcaca
    29281 taagccactc aaccaaaatc cactaacgat agaatctgta cccgcatcat ctcttattgg
    29341 cgtattttta gttgccaaca ccaaattttt atgatatttt tgactcgctt caaagaatgt
    29401 cggatcattc ataatagttt cccagaacca tttttcatga tcatgccaga taaaatgcgc
    29461 tccatatttg gcacaaactt ccaaatattt agcactatgc ggagctaact ggttattgta
    29521 aatccaataa ttctcaatat ttaaaacacc ttttaacaca ctatactttt ggaattgttc
    29581 atctaaccac tctggaggaa ctgtattacg ctctccagcc gacataataa ccaagaaaac
    29641 tggaatgttt agactttgag cttcctccaa catcttgaca taccattctc tcaattcttt
    29701 cgtatctcgt ggaatacaac ttgttggttt acagactttt gcaggatgaa gttcaatcgc
    29761 tgcatatggc tttacatctt caggaatagc ttcccatgct cccttcaatg tgttccccca
    29821 ccataatccg ttaccattat cattgccata caacggagaa agcaacaatg gcgattcatt
    29881 attaatcgtc gttctcattt gaacacgatt atcagcctta actcctgcta acaatccaaa
    29941 acataacatc ccaatacata caaacaatat tgtgattaat tttcttttta ttttttcttt
    30001 attcatgact tatacctaaa aatttaactc aataattttt tctgaattaa ataccaattc
    30061 aatattttgt acatcagtat ttttgccata tattcttact cttacttttt gatctttgtt
    30121 tcctccttcc aattttagga atgttatatc cccatttttc caagcaaacg ataccttata
    30181 tcctcctctt actctgaaac ctttcacttc tccttctgac caagcagaag gtaaagctgg
    30241 aattagtgat aaccaattat gatggctctg tactaataat tcacaaattc cactcaccaa
    30301 acctaaatta ccatcaattt gaaatggtgg atggtcaaga aataaattgc caagagtcgc
    30361 attatttaac aaaccattaa tctggttata agcaggttca ccttgatata gtctcgcaaa
    30421 aaaatgaatc agccatgcag cactccaacc tgtttgtgta ctagcatgca aaccacttac
    30481 taaccaatta ttaatcgctt gctccctctc ctgtgaagat aaaaaattag cgtttgataa
    30541 tctcctattg atagtgattt tagctgcttc tgctaattcc ggagttttat gaatatcaat
    30601 ctcattataa ggataaagcc caaatagagg tgaaatgtgt ctatgcccag gctctacttc
    30661 ttcataatct tctaaccatt cttggatttg cccattacta cctatttttg ttttaggtag
    30721 tttctttttt aactccttca cacgactaat aaaatccgaa ttgtctccta attgttttgc
    30781 aatgccaatg catgaatcac aaaaatatct tagaatttga ttatcaattg tagatgatag
    30841 acaagcattt ccttcaatac cattttttaa gcgatattta ttttccggtg agacacttgg
    30901 acctgtcatc aagtagccat ccacctcaaa taaataatct tcaaagaaaa gaaatgcttc
    30961 ttttatcatt tcaaaatgtt ccgtaagaat acgctcatct tggaaatata aatagtgttc
    31021 ccaaatatga gtacataacc atggaatagt taatacccaa attgcagccc ccatggcatg
    31081 agattgggga gccgtatcgc caaaaccatc cgtattatga tgtgctgtaa aacctctagc
    31141 tccatacatt ttcttagcgg ttagtcttcc cggttctctc attctttcga gcatatcaaa
    31201 taatggatat tctacttctg gtaaatcaca tggacctacc atccaataat tcatttgagt
    31261 attaatatta atcgtatatt tagaacccca aattggattt aattcatcac accatattcc
    31321 ttgaagattg gcaggtaaac cattcggttg actagacgat attaacagat atcttccata
    31381 atgaaataac aagttagtca agtagttact atacttttta gtgttttcaa gaagtagatt
    31441 cgttggaatg ctaagacaac ctttactata gtctagttta aaatcaactc tattaaattg
    31501 ctcctgatat ttttttacat gttcatcttt ttctgtaaag taatcaatac tactaaattc
    31561 tccctgaaga gaagaaatat ctatatttcc ccaataatcc gtcattgatt tgagataaag
    31621 aaatacctct gtagcattcc gaataactat tgtctctccc aatacactta cttcaccatc
    31681 cgtaacctta gaatgacata ctactttaaa ctgaacacct tttctacctc cagcagaggc
    31741 cgacattaaa attgtacttg aatccagttt agatacttcg tcattaaacc gtttatttct
    31801 acccaaatta atgtttaaat ttaatgtgtt ttgaactgat gacactatac ggcaacataa
    31861 aatattctta ttaaaactcg taaaatattc tctttttatt tgtaaattac aactattagg
    31921 ctcaaacaca acattagaaa tagctgtatc taaatctagc tctctttcat acaatgaaag
    31981 agcacaagac tgaatatcta tatgctcaat gtaaagttcc ccaagtaatt catagtggct
    32041 ttgatctctt ggggtagcaa acactgttaa ctttatcaat tcttcggctt tctgaatttc
    32101 tccatctaaa agatattccc gaattttttt aagatgcaat agtgagtctg gattatttct
    32161 atctgacttt cctctatacc aaatagtctc atcgtttagt tgaatacatt cttttgtagc
    32221 tgaaccataa atcataccac ctaaatgacc gttcccaatc ggcaaggctt cattccaatt
    32281 tgcggcagct ttcttatacc ataatttcac tctttacctc tcttccaaaa tggaggtgat
    32341 atcccaaata ccacctccac actttctact acttcaaaat tcctaaaaca actagaataa
    32401 ctccaatagc cataacacta aagattagta caaccggatt ctttcctttt ctaattaatt
    32461 tacacattaa taaagtcaaa gccataggga taaatcctgg aattaatttt gtaatcattt
    32521 cttgaacaga aataacaagt tccccctgct taaattctaa tccaaaatta ataccaacca
    32581 ttgatggaat caaaccaccc actagtacta gccctaatgc tgtcgccata ctcgtaacgc
    32641 gattcaatgt tccttttgta ttattttctt ggataagact agaaccctta gtatacccat
    32701 atttcaaacc gaaatattta acaggaatat taataatatt aaacaatatt aaggcgataa
    32761 agatacctaa agcaccgccg tctttagaat aagacgcacc aatactaaaa cagataggaa
    32821 ctagtgtcag ccagaacaaa ctatctccta gaccagccag tggccccatc aagccaactt
    32881 taataccagt aattgaagct gcaccttcat ttccttcttg ttcttccata gcggaagtaa
    32941 ctccaagaat aaatggtgcc gctgtttgat gagtattgaa aaactcaagg tgacgtttca
    33001 ttgcaggaga agctgaatct ttgtctgggt atagtttttt caatactgga agaattgtat
    33061 atagaaaacc taggttctgc attctctcat agttccatga agaaccatac ataaaacttc
    33121 gtttgaaaac ttttttaagt tcaactttag ttactttatt attcatcata gatcaagatc
    33181 ctcctcaaca tcactacttg aagttgtttc ttgtggtttg cttccaatca tatcgtagaa
    33241 gtatgctacc gcaataccaa ctagtgagat cccaatggtt gacattcctc catacacaga
    33301 acaaatgaat ccaatcaaca agaataccca catatttttc ttgagcatca tatttaaaag
    33361 cataccaaaa ccaattgaag gtagtaaagc acctgcagag ttaagtccct gcataacgat
    33421 tggtggaacc ttagcaaaca agtctgccac atattcccct ccaagcataa tagctaggaa
    33481 aattggtaca attttaaata acgtgattaa aaccaaactt gaataatgat aaaaaccgat
    33541 ctttgaataa tctccgtttt tagcatcatt atcagctttt ttcacaaaat aaacatctaa
    33601 agtttttgca agaacatcca actgttgggt agcaactgca attggaactg ctatagcgat
    33661 accagcagtt tctccttgac cagataaaat accaaatgca gtaccaataa tcgcacctga
    33721 aatagtatct ggtggagtat aacctccaat acctgttaca ccgagccaag ttaattcaag
    33781 agctgaacca ataagaacac cttgggtgaa atctcctaat actaagccaa ccattgcact
    33841 tgtaactaac ggacggtgaa tcataaataa cggtccatta tagtcaatag tggcaataat
    33901 cccaactaat gtcaccagta atgcttgtgt gaatagcata tactgtacct ccttaaatta
    33961 tttttataaa aatttttcca acattgtaac tttatcatta ggaaccattt gaatttcaac
    34021 tctcgttccc ttatcaacta ttttcttaaa ataatatttg tcttcttcac ctagagctac
    34081 acctcccgtt accttttcat tttcctccgt tttactcatc tgtcctacat tgaggtactc
    34141 caattttaaa tttccttcaa tagaatcata cacatctttt ggatttgtat atatcagcat
    34201 tgttctcttt tttattggca cagagtttaa aacttccaca aaccgtttta cactaaagaa
    34261 aacaattttt aaacctaccg gtgcagaaat ctttaaaata gattgtcgtg ttttatcttc
    34321 tgagatgcga tcattaacaa tgataacttg ctcaatatca tactttttta gccacgtagt
    34381 gacaacttga ccatgtacca gacggtcatc aatacgaaca aactctatag acataaatct
    34441 tcttcctcct ctacgttaag ttgttgttta acattaaaca aactattttg agcattgtga
    34501 acaatttctt ctaaattgat ttttgaatca taacttgata ttaattccac taggagaggg
    34561 atattaaacc ctgttacaat atcaactgaa tccaaattta aaaaccgtga caaagccaca
    34621 ttattaggac ttcctccaat caagtcagtc aaaacgataa cctcttgatt tgagtctaac
    34681 agttcatcca cttgattttt aaaataatgc tcaaactcta caatattctc tccaggcatc
    34741 aaacctaatg tcctaactct atcatttgtt gtctcaccaa caaacatttc tgcggtcatg
    34801 agagctccgc tagcaaaatt accatgactg gcaactaaaa ttcctctatt gaacattttc
    34861 tctttcaaca actactcctt tcttaaggat aatattagca taaagtgaag tttctcctgt
    34921 agcaacaata gcataagctt tcttactacg ttcataaaag tcttctcttc taagataagt
    34981 aatcgtttta agatctgtac catgaccttc aatcatctgt ctataggtac cccatatctt
    35041 aggaatatca tcacccgaaa caacgttcat aaactgaatt gaactatcga cgtaactatc
    35101 taatggcatt aaatacagaa tggaatctaa taattctgga atatttacac catcacaacg
    35161 aattagctta tttgcacatg aggcagaagg ataattcgcg tcagctaata ctatttcatc
    35221 tccatgtccc atttccatta aagtcttcaa taaatctgga gaaatatttt tcggtatatg
    35281 ttttaacatt aatatcctcc ctattttctc tgaccgtatg ttttaaattt ttctgccatc
    35341 aattccatct cctcatcagg aagaactact ggctctccaa aattcttagc taaacaataa
    35401 atttttgcac aatattcaac ttcttcaaca atattaaatg cattcaataa attttgtgca
    35461 cctgctaaaa ttccatgatt cgctagtaaa actgctctac gaccttccat tgctttagct
    35521 gcattcacag ccaattcttt cgtgccatat gttgcatact cagctacccg aacatctttc
    35581 cctgccactg caatcatata atgactcgct ggaagtggtt ctctgagaca agctaatact
    35641 gttgcataag ttgtatgagc atggataatt gcatcgatat catcacgagt ttgatattga
    35701 atcaaatgca tataccattc gctagatggc aagcgttctc cctctacaac atttccatta
    35761 atatccatca ctacaatatc ggattctttg atttcaaaga aatcaatacc cgacggggta
    35821 attgccatca attgtttttc acgatcgaaa acgctgagat tcccacctgt tcctttcgtc
    35881 aaatctgttt ctactagctt cttaccatat ttaattaatt cttgttttac atctgacatc
    35941 cttgtcctcc tcatatcaaa acactaaata tttttcaatt caccaattat ccccccttcc
    36001 tgcacaaaag ctaagaaggg ggagggaggc aaatttacaa actctcaatc tttttaattc
    36061 ttttgggagt aataactctc taattgtaga aactcctcaa taacatggtg agcctcttcc
    36121 atccctttta attgtcccat agctatgagc tgcacaacaa tattccccac agctgtagcc
    36181 tcagtcaaac ctgtaagaac ctctttacca gttctatcag caatcatttg gttaaagtaa
    36241 ctggctctag cacctcctcc aatcacatat atcctcttat aaaccttatg agttagttct
    36301 tctagtaact ctatcgcttt cctatacgtt tcagctaggc tttcataaac aatcttaaat
    36361 agttgtccat ctgtccactc tctagtttca tgatgataag ctagatattc tgtcaaagtc
    36421 ttgtgcatat cagattctgt tgcaaattca gttgattcag tatcaatcag aggaagattt
    36481 tctttttctt tctccaccat tgtcctaata tcatcaaaag aataggcttt ccctcttcgt
    36541 tcaaatgaac gtcttagttc ctctatgatc cacaaccctg tacaattctt cagaaatgta
    36601 atcactccat ctttaccgac ttcatttgta aatccataac tgaaggattc ggtagtaaga
    36661 atcggtgaag taagttccac tccaaccaaa gaccaagtac ctgatgaaat aaataaacta
    36721 ccttctgtct taggtactga gacaatcgcg cttgctgtat catgactaca aacattcaca
    36781 acaggaatat cgcctaaacc atactcctct tttatccttc caagaacatt tccctctgaa
    36841 acaatttcag gaagtaaaga tgaatccaat tcaaatagtt ttaagatatt ctgattccaa
    36901 ttttgactcc taggatcaaa taattgagtt gttgaagcaa tgcttttttc tgtagcaaac
    36961 ttacctgtca agagataatt aaacaaatct ggcattaaaa gaatcttatt ggtcttatag
    37021 aaagagtcag gagattcttg acgtgcctta aagagttgaa acaaggtatt tatctccata
    37081 atctgatttc ctgtctctga atacagtttt tctaattcag tcatttcaga tatttccttt
    37141 aacactccct ttgttctttc atcacgataa tgaacaggtt gtaataacag cttaccttca
    37201 ttatcaatca gtccaaaatc aactccccat gtgtcaatac cgatagataa aatcttgtaa
    37261 ctagtattag ccaagcggat actttcaaga attttagcta gtagaaagtc aatatcccaa
    37321 gataaatgcc cttttactct aataggtaga ttagaaaagc gatttatttc ttccattact
    37381 agtttatttt cagaaaggta accaacgatt gctcttccag aagtcgcacc taaatctatt
    37441 gctaaaaccg cttccatttt tcttctctct tcgtccttga ttaactttat tataatcccc
    37501 acgttttatt ttttcaatat gtgaacgctt acttgaataa tgttcaaatg ttaacccaat
    37561 attcataaaa ataattcaaa ttcctccaat ttgtgctata atatagttga aatgataaat
    37621 taggaggagc ttatgataaa agatgaacgt gtacttgaat tgattgaaat tatcaaaaag
    37681 aaaaaaagaa ttgccgtaaa agagctggca gaaatcactt tctccagcac aagtacctta
    37741 cgtcgtgatt taattttctt agaaaatcaa ggtcttatca aaagaaagca cggatacgtg
    37801 accctgtcct ctatgaacac aattgaactt tctcatcaaa tacgtgaagg agaaagtact
    37861 aggcaaaaaa gactaatcgc tagtctcgct aaagacttta ttcggtctgg tatgtgtatc
    37921 tatctagatt ctagtactac tgtctacgaa ctctgtccct atctttctga acttgataat
    37981 ttgattattt ttacaaatgg tttacatact gcacaaaccc tatctgaaac tgttaaagat
    38041 agctccaaaa tctttatcac atctggcgag gtcaaacatc aatcctgttc cgtggtcaac
    38101 tatgataagg aaaattcttt attagatcat tttaatatcg atttagcatt ttgttcagca
    38161 agaggtattg atgaccaata tgtttatgaa gcttctctca gccaagctat ttcaaaaaag
    38221 aatattattg acaaagccca tgaaaccatc ttactgattg atagttctaa attttacaag
    38281 actggatttt ttaaaattaa tcccctctcc aaatacacaa cctttatttc agacaccgtg
    38341 ccagatcaaa aattattaga cgcagtcgaa ttatttgatg gagaatgggt ttctgatatt
    38401 caatgaaaat caaataggaa gctagtctca gcttgctcaa agtacagatt tgaaaattga
    38461 tcaagtcagc tcgaaacact gttttgaggt tgtagataga actgatgaag tcagtcacat
    38521 atatacggaa agacgaagct gacatgatgt gaagagattt tcgaagagta tcgttctgtc
    38581 tgctgactga tttacaaata ttcaccacat gacattattt tcttagcaac cctaaaaaca
    38641 gaggctggac aaaaactcaa tttcaggaga aaatggagta aaccttccca caataaaacg
    38701 catagtatca agtttttgca cacctgatat tatgcgtttt tctgatttta aagatttttc
    38761 tcttagatct gatatttcaa gaattaagtg accttgatga tctaaatgta ttgtggtata
    38821 ctatttttgt catcggttac cgattacgtt cctatgggtt cgtgagagga ggtgaaacta
    38881 atgagcctta tcatagagct cgctcttact attatagcgg atgttatagc tggaattatc
    38941 ttgtatttcg tctgcagatg gctagatagt aaggagtaga ccgactgact agcctataaa
    39001 cacccgttaa atcgctaaga tacgtcaaaa aagcccttaa ctacggccat agttaggggc
    39061 tttggtgttc taatgaacct tatcaattaa ctacattcta gcatataatc tacaatagtt
    39121 caagcattaa gtaaggttga tgacctgaat gtagtgtgat atactatttt tgtcatcggt
    39181 taccgattac gttccttacg gttcgtgaga ggaggtgaaa ctaatgagcc ttataccaga
    39241 gcttgctctt actattatag cagatgttat agctggaatt atcttgtatt tcgtctgcaa
    39301 atggctagat ggtaagaagt agaccgaatg actagcctat aaacacccgt taaatcgcta
    39361 agatacgtca aaaaagccct taactatggc actagttagg ggctttggtg ttctaatgaa
    39421 ccttatacac taactacatt ctagcatata agcccagata tttcaagagt tttatttatt
    39481 gtttaaagtt ctgaaaggtc tataatgaag ttagccatct agtatcaaaa aaccgactag
    39541 ctcttatgaa ctagtcgatt tctcatcaat gcgccaacat ttcttgggcg atttcttggc
    39601 cagataggtt atctgggtag taggttggcc agttgtccat ttcttcaaag agggcttctt
    39661 ggcttgtgcc tccaaagaag atatggaaat gttctgcctt aactggggca acattgtggt
    39721 cactaaactg aacatacttg aattgtccag cgtcagcatc tgtggcttca aagaggaaac
    39781 gcacgccacg attgcctttc ttgtaagtca aaattttctt accgacatac ttgtaagtgt
    39841 atttcttgct ttgtccacct tgaacaaatt ccatagtatt atcagtaatg ttaatcttag
    39901 tcacatctgt atgatagcct tttgtatagt aagccttgta ctcagcctgg gtcatcttac
    39961 cagtcaactt agccttgtag tcaaagactt ggtcaaacgt gccgtcttca aggaaaggat
    40021 aaactgattg ccagttacct gcatagtcac tcaaggtgcg gtccttgaca gctgcatcct
    40081 cgaagtaacc attttggact gtcttggtat cctctgcctt ttcaggttca attgctgggc
    40141 cttcttggtc tgttgtttgt ttcaaagcct tgaggttttt ctccatcacg gaaatgtagt
    40201 tttctccagc cttggtgtcc tcttctgtca gactttctaa aggattgagg acatcagttt
    40261 tgacacctgc ttcttttgaa agtgtgttag caagggcttg tgaggcattt tcttcaaaat
    40321 agatataggc gattttattt ttcttgacat actctgtcaa ttctgccaag cgagcagctg
    40381 atggctctgc atctggagaa agtcctgaga ttgcgacttg tttgagtcca tagtccaagg
    40441 caagatagtt aaaggctgcg tgttgagtca caaagctctt ttgttttgct tgagacaaac
    40501 cttctgcgta agccttatcc aaggcttgca atttttcgat ataggcagct gcattcttct
    40561 caaaggtctc ttttttatca ggataatctg ctgacaagct gtcgcggatg tgctctacta
    40621 gtttaatggc acgaactggt gataaccaaa catgggggtc aaactcatgg tgatgacctt
    40681 cttctccatg gtcatggtct ccctcttctt cctcgccacc tggcaagagc aacatatcgc
    40741 ctgtcgcctt gatggttttc acttttttct tatccaaggt atctagcaat ttaggtaccc
    40801 atgtttccat gttttcattt tcataaacga aggtatctgc atcttggatt ttggcaactg
    40861 ccttggcaga tggttcgtat tcatgaggtt ctgtcccagc accgattagg agttctacat
    40921 tagccgtatc tcctgcgact tgcttggtaa attcatagac agggtaaaag gttgtcacga
    40981 tattgagttt accatctgcc tgtttttgat tggaacaagc cactaaaaac aaggcacata
    41041 gactggctag taataagcta atttttttca cgttcgtctc ctatttgata aaacgtctta
    41101 ctaaactgat tagtataaag acagttacaa aaataatggt aatacttgca cttgcaggtg
    41161 tttctgcata gtaggaaatg taaagtcctg ctaccattcc caaaaagcca atcgcactgg
    41221 caagcagcat aaccgattta aagtttttcc ccagacgcag ggcaatacta gctggcaaga
    41281 ccataatggt cgataccaga agagctcctg ctgcaggaat cataagggca atagccaccc
    41341 ctgtcaccat gttaaaaaga atggacatgg tacgaactgg caagccatcc acaaaggccg
    41401 tatcttcgtc aaaagttaag atatacatag gacgaagaaa gagaaaggtc aaaatcaaaa
    41461 caaccgccgc aatgacaaag agggaaatga cctgttcttc actgatagtc acgatcgaac
    41521 caaagagata ttggtccaaa ctcattgaac tcgagctttt acccttgctc atgacaatca
    41581 gagaaacagc cagacctgtt gacatgagga tagctgtccc gatttccata aagctcttgt
    41641 aaaccgtacg gagatactcc agaaagaccg ccgcaatcaa gacaatggca atagtagaaa
    41701 cagttggaga aatccccaaa accagaccaa aggctacacc tgaaagtgag acgtggctaa
    41761 gggtatcact catcaaactc tgacgacgca agatgaggaa ggttcccaat accggtgaga
    41821 aaagactcat agcaataacc gccaaaaagg cgcgttgtat aaagtcgtaa gataataaac
    41881 taagcatggc ccacctcctg gccattctca tgaacattga aacaacgcca tggcgagtct
    41941 tggttacgga ctagatgaat attgcgatcc gcataatcct taacttcttc agggtcatgg
    42001 gtaatcatca aaacagcctt gccatgatga tgggcgctgt ggtgcatgag ttcgtaaaat
    42061 tcatttttac ttcctgcatc catccccgtt gtcggctcgt ctaggataaa cacatcaggg
    42121 tcagaagcaa acatacgcgc aattaccgct cgctgctttt gtcccccaga tagagacccc
    42181 aagcgtttgt ctcgatgttc ccacatgcca actgagtcca gactagcctt gatatgctcc
    42241 tcatcatgag cattcaaacg acggaaccag ccttttctcg gatagcgacc cgacttgaca
    42301 aattcataga ccgtacttgg aaaaccagca ttaaaactgg caatttgttg aggaagatag
    42361 gctattctca atttcttacc ttgcgtattt gtctttgaaa tagccacctt tccaatgcgt
    42421 ggttgcagaa ttccaagact agccttgatg agcgtcgtct tagccgctcc attttcccca
    42481 gtcaaggtaa caaattcccc actatcaaca caataattga tatgttcaag aacaggctcc
    42541 ttatcataat agaaggacaa atcctctacc gtaatatatc tcattatttg atttctccta
    42601 ctaaagcagt caaaaaccgc tgaatcactt tttgttcatt tggagtaaac tgagtcgcca
    42661 cttgttcata ggttaaaagt gtatgctcat ggtgatggtg gtgctcctca gcgattggac
    42721 gagccaagtc agtcaactga taaaaaatca cacgcgcatc tttagaatct ttagatgttt
    42781 ccaacatccc ttccttgacc aaagacttaa tggccttggt aactgccgcc tgactgacat
    42841 tgagacgacg ggccaattct gaatttgtta aagattcctc tgacaagagc ataaggatat
    42901 gctcctgagt attggtcagg gccacctcgc tagtgcaatg acctattagg atttcatgct
    42961 gattttccgc ctgcaaaatc acctcattca aaaaagcatt gatatccttt gctagctgtc
    43021 tcatatctga ctcctttcct tttagacttc tcttttttaa gagaaaaata ctattctttg
    43081 acattttgtt taccagttaa ttatatcaca agcaaaaaaa gagtcaagaa aaaacgtgaa
    43141 aactagtttc attcttgaac tcttctatat tatattatct attgaaattc tttgacatct
    43201 ccatcataag tcgcccaatc tttgctgaaa aagcgctcat tcagatggta agtcggagct
    43261 ggtgtgggat tggataggaa aggatcaact gccttgtcaa aagccaacca acccaaccaa
    43321 ccaaggtgaa tggtgtcctt cataaagaaa ggctccccgc cgtccttaga aaaatctgct
    43381 atattggtaa aaccttgact ttctaactgg tagcgaatct tctgcaccgt ttgttggtac
    43441 atatcctctc gtagaccagc atagttcatc cattttttat taacaggtgg aatgataaaa
    43501 atcgggttta ccttagattt agaaaactgt gttaaaacca actgcaagtc attatactct
    43561 ggcgacttga gataggtaaa gcttttctga gaatccttta atttcttcaa atccttcttg
    43621 atctgctcat tatagaaata attttccatt cccatctcat tattggaagt atttttttca
    43681 gcatctgctt tgacaacatc ttctattgcc tgataagaaa actggtctgg caagattttt
    43741 aaatacttag ctacatgctt atcgtagtta acatagcctc taaccgaaaa ctgaccaaaa
    43801 aaggaagctt ggcgttcatt aaaacgagcc aataattcaa tcatttcatt gtctgctgtc
    43861 gacaattctt ctttacttgc caacttctga accaggtcct tcatagctac gtttgggaac
    43921 tgttgcagta agcgagtcgc tgcatattga ctagcctgat ccccagattg atgtttcaga
    43981 aaactagtca actggtctcc attaaaatac tgctggaagg ctgctggatc atagccattt
    44041 ttactgaacc actgaggtga gataacatac acaacttgtt tattctccag ctgtggtaac
    44101 atctgttgca ttccaaaata ttggttaagc gatgcagctc ccccctgtcc taaaagataa
    44161 ggacggtagg aacgattgta tttctcagct aataccgcag gatgagcacc gtcaaaacga
    44221 agccattcac tagagccaaa gaagggaaca aaacgcacat ttggatcaga tagtgctctg
    44281 actttttgac ttcgctcctt aaaactatcg atagtagtag ccactgctga acgcttttca
    44341 gctcctagat tatgatgcat ctcagtagga taaaagaaaa tgagcagaaa aaccaacaaa
    44401 ccagcgatca agaccggtcc gaagatcatc cataagcgtt taagcatttt gtagctccac
    44461 aataccagct atgattttat tagctgtatt ccagtcgtca cgaccaaact ctgttacagg
    44521 gacacgaatg tcaaaacggt tctcaatctc cacaatcaac tcaaccgttc ccatactatc
    44581 caagacacct gcatcaaaaa gatcttcatc catcatgtca gaaacatctt ccataaacaa
    44641 ctcatcaata atttcaataa cttctgattt gatatccata ttttatttcc ttttattttt
    44701 taaaccatag attattcaag aatccagaaa agattaagaa tgacaacatg acaacatgga
    44761 aagtgacaac catgccaagc aactgaatcc agcgattctc aggtagggca gccttccctg
    44821 cttttttccg ttccttattg agcgtttttt tcttgcgaac ccaggcatca ttgatgacca
    44881 agcctagtcc atgaaagagt ccataggcga tatagtacca ggtcacacca tgccaaaatc
    44941 ccataatcag catatttaca atgtaggcca tgcttgaggt tacattacga tttttaaaga
    45001 ctttctttct ggttaacacc atcaccattc gcataaagac aaagtcacgg aaccagaagg
    45061 acagactcat atgccagcga ttccaaaact cctttaaatc ccttgataaa aagggcttgt
    45121 taaagttgat agggctacgg attcccatca agtttgagat ggccaaagca aacatagaat
    45181 aacctgcaaa gtcaaagaag agttccagac caaaagtata cataactgcc aaggcataga
    45241 gattaaagaa gccacctgac tgcaaggcta aattcttcag aggaggtagt aaggtctctc
    45301 ctaaaacatg agctaggata aacttataca aaaagcccca catgatatag cggacagatt
    45361 catccagcat atccatcaac tcatctcgct caggaatagc ctgataattt tcattaaatc
    45421 gcttaaagcg atcgattgga ccactcgaga aagttggcat gaagagaagg aaacggagga
    45481 attcccagag ggtaaaatcc ttaatcactc catctctcag ctcgatgaca attccaaccg
    45541 aacgaaaggt caggtaagaa attcccaaga acccaagcaa agactgcgtt ccattgatag
    45601 ctggttgcac cttgacaaag ataatcggaa gtagggacag aaaactaact aagtagaaga
    45661 cccacttgcc atccttgctt tttcgataat gcttgtagaa aagcaggagc aatatttccc
    45721 agcaaaggta aatacccaag gcagctagtt gattggtctt tccacccacc aacatggtga
    45781 caataaagaa gagacttacc aacacttcat accaggcaaa gcgtttcttg aaaaagagac
    45841 ctataaagat gggcaaggtt gcagcaatca cataaacaaa atactgagga ttgccatatg
    45901 gctctaaatg aggaagctgt tgaaaaaact ccatcatctc ttattcacct cgttaatcaa
    45961 tcctttgatg tcaatctttc catttggagt tagtggcaaa ctgtctcggt aaaggaattt
    46021 agatggcatc atataggaca tcatgatgtc tgtcaggtct tccttgatgg ccttggtaat
    46081 atcgatatct cgctcaaact gctcacgaac accgtctttt aagatgacat aagccaatag
    46141 attttgtacc ttgtggtcct tgttatagcg cggtactgcg acagcagatt cgataaagcg
    46201 agacttgttg aggttttgag agacatcttc taactcaatg cggtaaccgt taaacttaat
    46261 ctggaagtcc atgcgtccgc cgtagagaag caagccctca tctgtcatgg ttcccacatc
    46321 gcctgtgtga taggctggca gatcttcaaa ctcaaagaag gcttctgctg ttttttcagg
    46381 attgttcata taaccttttg aaacagctgg cccagaaaca atgatttctc cctgctcacc
    46441 atttggcagt ttatttcctt cctcgtcaat gataaaggtt ggagaatcag ccttggtata
    46501 gccgattggt aggcgtttga gagtcgctaa catctcgtct gtcacggcaa ctgctgacag
    46561 agctactgtc gcttctgttg ggccgtaagc attgatgata cgggcatttg ggaaacgctc
    46621 gcgcagtttt tgagctgttt tgaccgtcaa ttcttcacca tcaaagtaga aatgcgtgat
    46681 tccaggcatt ttctcactgt tgaagtattc agacaacatg gccatatctg caaaggatgg
    46741 tgttgatgtc cagatagcga ttggcaatga aaagatagcc gcaaagagtt gcttaaagtc
    46801 ctgagtgatg actgaaggaa gagtgaaaag cgtaccacca agtgccaagg tcggtgccca
    46861 atacatgaca gacaagtcaa aagaataagg tggctgtgcc agcatttgcg gacgactcgg
    46921 tgtcgcaaat tccttatccg taatcatcca gtttgtaaag ctgaggagat tatcatgtga
    46981 aatctgcact cccttaggct taccagtcgt accagaagta aagataatgt agtaattatc
    47041 atctcccttg actggatgcg tgatttcata gttattccct tgggcaaagg cttcttgaac
    47101 ctgagctaga tttatcattg gtgtagaaac ctgctccaag ggaaaggctg aaatggcaat
    47161 aatcaagctt ggctctgcta cttctaaaat agctgaaact cgctccaagg ccgaatggct
    47221 atcaattgga atgtaggcat gacctgactt agtcagcgct acaaaggttg ccaacatttc
    47281 atattcttgg ccaccaaaaa caaccacagg agacttctca ggcaagccta gttggtcaat
    47341 gactgcagcc aaactatccg aatcagcctt taaatcgcca taagtgtgtt cctgccccaa
    47401 aacattatag acaggatagc taggctgtgt ctgagcaaaa tgctcaatgg tttcaatcat
    47461 atctgctatt ggtttatttg acacaatagg gattctcctt caagttaaaa ttcattatag
    47521 ataaagcttc cttgaccctg accaagatag ctaaagaagt aaagcagccc tagaaagata
    47581 agaaaataca aggctgtccg accaagaaag aggtacaatt cttttctctg tttcatcaag
    47641 aaaaaccatt catttctgta atttttcgct aaaataagag tgattcttac tagcttattt
    47701 ttctaccatt gtaccacttt atatagtatc ttttcaattg tttaccgtat gtttccaata
    47761 gatttcagct tattttaagg attatacagt ttttctatgt atattttcaa atagagtgat
    47821 cctgcttcaa aactccattt caggagacaa tgaagtaaat cttcccataa taaaacacac
    47881 aatatcaagt tttttcaaca cctgatacta tgcgcttttc tgatttttaa agacttttta
    47941 accactctct catttaaaat aatctcgtct gatataaatt aaaatagctt ctatcatcag
    48001 acaaatggct gatagccaaa aactgatgct aataccaaaa ctctcagtaa tatagctcat
    48061 tagcaaaaca aatactgaaa atgctaatgt agaaatcact tcaagaacgg aatagacatt
    48121 aactaaatga ttttcctcta ctgtttcctg aagaaataca ctttcaggaa cttcttttag
    48181 ttgcgataac ataccaacta aagctgaaaa taataaaaac atctgtgcgt ttggaaaata
    48241 tagaatagtc agtgtcacta tttccatagc tacaagagga aaaagaatac tttcccattt
    48301 agcagcaagg aacttttcag atagcctaaa agcaattaag ccactaatta taataccaat
    48361 agagtatgct gtattagaat atccccagta actttccgtt ttatttaata actccgttac
    48421 aaaaacaagt ataatggaag aaacccaaat cgtatttgaa aaaatttcca ataaatttgc
    48481 tgatacaaaa agtcttaatc taggatttct agcaactaac ttccaacctt tgagcaaaat
    48541 ttcaagatta gtttctgact ctaacacctc cacttcagcg ttaggaagaa ataacatcag
    48601 aaagctagaa atgatataca agactaaatt gatacacgtg gtaggtaaca gaccaattgt
    48661 tgcaaacaag agtccaccta atccccaacc tatcaattga acagcttcac cagtcattga
    48721 taaggctgaa ttagccttac ccaaatcggt cgcatagcgt ggcacaatag cataggaaac
    48781 gggtgctgca aaaccatcta gtatggaaat tgcaacaaca aatagatagg tcaccaaagg
    48841 cgctacggat tgcattacgg taaacattcc taccagtatc gccaataata tagtctttcc
    48901 aaattgagat aaagataaaa ccctatttag cgctaacctt ttagtaacca acggaactaa
    48961 aagactcgca acaaaagagg atattcctat taagatagga actagtgatg tggcaattac
    49021 tgattttgaa ataatgtata tgttagcaat gattgttact ctaaagaaaa tatctgctaa
    49081 atttgcaaat aattgagaga ctaacaactt gacaaatgaa ttagacatgt agcgctcccc
    49141 ctttagttac aaactttgga attaaatttg atttttaata ttttagcata aaatagcaga
    49201 aaacaaaagt gaggtttttt acatgaaaaa acaaaaacta ttgcctttat tattcctaat
    49261 tttaggagga attatgatta tcgttgttgg ctagtactaa gaagttagtt agttagtaga
    49321 ataattacat cttcaatcga aaaagagact ggaaaaagtc ttaaaaatca gaaaaacgct
    49381 caaatccttt ggcgctctaa gcttttctaa tgatagattt agatagtcaa aaaaatatct
    49441 gaaaagttcc caggatcgtc gtctcagcat caaaaatacg tgaaatttgc ataattaaaa
    49501 taaatttcag gggagttaat cgagtagggg ataatctcta gcccctctca caccaccgta
    49561 cgtgccgttt ggcatacggc ggttcaacta acttttaacg catgtcgttc aaggtaataa
    49621 tccaaacacg aaaccagtcc acgtttttcc aggactggtt ttgatatagc acgtttaagt
    49681 accgacttct gagctactaa ttgataatgg tcgccccagc cagatacctt atctgctatc
    49741 catttaggaa ctcctaactt aagcaatccc cataatcgtc tcgatttctt cttccattgc
    49801 ttccagataa tcactcgtag gcgagtacgc aagcgctcat ctatgctggc gactatactt
    49861 ttcatatttc ccaatgagca atagtttatc catcctcgaa tagacaaatt cagttgctca
    49921 atacgtcttg ttaggtctat actccatttc ctctgtgtta gtttcttcaa tttaaactta
    49981 aatctccgaa cactatcttg atgtggacgg cttttccaac catctgataa tttccagaac
    50041 ccaaaaccta gatatttcaa ctctcttggt catgtttact ttcaaaccta gccgtttctc
    50101 aataaaacga ctgactgaat acatcacacg cttagaggct gcctcgcttc cgaccgtaat
    50161 cacacaatca tctgcgtagc gcacaaatcg aagtcccctc ttttctaatt ccttgtccaa
    50221 ttcattaagc atgatattgg ataagagagg agataaattt cctccctgtg gtgtaccaac
    50281 tagtgtttta taacgttgac cattaatgat aacacctgaa tgaagatact tacgaatcaa
    50341 ggattccgta tctccgtctt cgataatgtt atgtactaag gacatcaatc tatcttgagg
    50401 aactgtatcg aaaaatttct ctaggtctaa tccactatcc actcatagcc gtcatttaag
    50461 tattctaaga gcttcatgat ggctttttca catgacctat ttggtctgaa accataactc
    50521 gtatctgaga aatggggttc acaaatgggg ctcatgactt ggacaatggc ctgttgaatc
    50581 attctatcca taactgttgg aattcctagt tgacggatgc ctccgtctgg tttaggtatc
    50641 tcaactctaa gaactggttg aggcttatat tttctctgtt ttatcagttc cttagtcaag
    50701 cgccagtttt gtctgagata attatccatc tcttcgatag tcattccatc aatcccagct
    50761 gagcctttat tggattttac ttgattgtag gcttccagca tattttcgcg tgataatatc
    50821 ttatctagca gttttgacat gtgcgtattc ctttcttatt ttggtgcctg agggacatct
    50881 tatattggtg aaccttcatc tagtcattac gtgtcaaagt ccagttctat cagaccactc
    50941 attttacaga cacaagtgaa gtaggattac ttcgatctgt cgttttctct ttctagcgac
    51001 agacctcaaa cagtctctcc ccagactgtt tgagtattca ccccttcgct ccacttccat
    51061 tacggaagtt tcctcactac tatgggctcg gctgacttct catgattcgt tgttactacg
    51121 ctttcagcgc tcatgaaacc tcacgggata agtcgtacat ctttcctcgt ttatacaaga
    51181 tatgaggacg ttaaaaggtt acagtgaaaa taggaaatct gacgcagagt ctttagactc
    51241 tagaaagatt tatctttttc acacaaacct tagtccgaat tcaattactc tcgtgattta
    51301 cacatatagg ttacgactac ctttttggac tttagagttt gaagcctcct tatccgctat
    51361 atacgcctta ctatcacgtt cctgttcgta gagccacgat ttcgctatcc cttcctctcc
    51421 ctgctacctc acgatagtca ggcttgggaa tcgctattgg gttcaccggt agcaggtgcc
    51481 caccgaggac ttacacctca gatatacgac atgcccgtc
//
LOCUS       DAVKEV010000009        48823 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVKEV010000009 DAVKEV010000000
VERSION     DAVKEV010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48823
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.009"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..137)
                     /locus_tag="VWZ68_000512"
     CDS             complement(<1..137)
                     /locus_tag="VWZ68_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9371591.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     G"
     gene            314..1759
                     /gene="cps4A"
                     /locus_tag="VWZ68_000513"
     CDS             314..1759
                     /gene="cps4A"
                     /locus_tag="VWZ68_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEU9371592.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVITALVLLVALLGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAVYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNMPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            1761..2492
                     /locus_tag="VWZ68_000514"
     CDS             1761..2492
                     /locus_tag="VWZ68_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEU9371593.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKVKELFVDNPRKIIMDQLI"
     gene            2501..3193
                     /gene="cpsC"
                     /locus_tag="VWZ68_000515"
     CDS             2501..3193
                     /gene="cpsC"
                     /locus_tag="VWZ68_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEU9371594.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSMTRIYVVNRNQGEKSGLTNQDLQAGSSLVKDYREIILSQDVLEEVVSDLKLD
                     LTPKDLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPATSPSSPNIKRSTLIGFLAGVIGTSVIVLILELLDTRVKRPKDIEDTLHMT
                     LLGIVPNLNKLK"
     gene            3203..3892
                     /gene="cpsD"
                     /locus_tag="VWZ68_000516"
     CDS             3203..3892
                     /gene="cpsD"
                     /locus_tag="VWZ68_000516"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HEU9371595.1"
                     /translation="MPTLEIAQKKLEFVKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PEEGKTTTSVNIARSFARAGYKTLLIDGDTRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGTVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTATGEVNKRDVQKAKQQLEQTGKLFLGVVLNKLDISVDKYGVY
                     GFYGNYGKKII"
     gene            3903..5270
                     /locus_tag="VWZ68_000517"
     CDS             3903..5270
                     /locus_tag="VWZ68_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU9371596.1"
                     /translation="MDEKGLKIFLAVLQSIIVILLVYFLSFVRETELERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFETMG
                     IDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHVIAKRIIDIMGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYVQYTSE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFM
                     RDGAK"
     gene            5274..6017
                     /locus_tag="VWZ68_000518"
     CDS             5274..6017
                     /locus_tag="VWZ68_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HEU9371597.1"
                     /translation="MRDRIQLLGVTIDLLTMNETIDIVEQYVLEKRPLHLMGVNADKI
                     NQCHTDEKIKKIVNESGIINADGASVVLASKFLGTPVPERVAGIDLMQCLLELSNKKG
                     YSVYFFGAKEEVLQDMLKVFKRDYPNLIVIGHRNGYFSEEDEQAIQEDIREKNPDFVF
                     IGITSPKKEYIIQKFMDSGVNSVFMGVGGSFDVLSGHIQRAPLWMQKSNLEWLFRVAN
                     EPKRLFKRYFVGNISFIGRVLKAKRGVKY"
     gene            6014..6838
                     /locus_tag="VWZ68_000519"
     CDS             6014..6838
                     /locus_tag="VWZ68_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HEU9371598.1"
                     /translation="MNQTEMIRLIQKVELDAIKEFKKICEENDIDFFLRGGSVLGAVK
                     YDGFIPWDDDMDIAVPREAYDKLPSVFKDRIIAGKYQVLTYQYCDTLHCYFPRLFLLE
                     DERKRLGLPRNTNLGLHLIDIIPLDGAPNHSVLRKIYFGKVYWYRFLASLGTTYVGDH
                     VDMHSTKQKLIIGFFKKLGFAKLFPQNSVYRRLDNLYKKYDWKKQKYAGTINASLFAK
                     EVMPVEIWGEGVEKPFEDTFFKVPTEYDRYLKRLYGENYLYEEPSDDEKKSHLGGH"
     gene            6840..7718
                     /locus_tag="VWZ68_000520"
     CDS             6840..7718
                     /locus_tag="VWZ68_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9371599.1"
                     /translation="MFCYIILHYKVLEETISCVKSIKEGNYNAKQIVIIDNFSNNGTG
                     EKLQELYESDLEIDVLINHENAGFARGNNVAYQFAKEKYNPDFMVIMNNDIEIETENF
                     EKIVTDIYREEKFHLLGPDIFSTTYQLHQNPKRLTHYTYGEVKALNEKFKKGSQVSLA
                     LKIKCWLKASKVLRTAIYQNRRKKGSVDYRKQVENPILHGSFIVYSRDFIEKEEYAFN
                     PNTFFYYETEILDYEAELKGYKRIYTPKIRVLHHQNVATNQVYTNLLEKTLFSNKCNF
                     KSTSYFLKLMKENEDV"
     gene            7719..9056
                     /locus_tag="VWZ68_000521"
     CDS             7719..9056
                     /locus_tag="VWZ68_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HEU9371600.1"
                     /translation="MSYLFLLCLTLFLLTIFYFFAFIQDLIAPPVVMSVMFLISSVFA
                     LVNSKNWNIEYSGIAYILIISGIIIFSLPLMALKSPNFNTEVKIADRLIDIQFWKIAL
                     TIIIDLFILYLYRKEIYNLVLSNGYTGSNIQWFFRNATSYEGELTVRTFIRVLIRVID
                     VSAYIFGYTFINNFLIYRHKRPKDILLLVPLLIFISKTLISGGRQDIIKILIAYVIMM
                     YIQQKRKVGWNRVISHKYIHLGFVGLIAGIPAFYYSLFLAGRSTTRTLFESVSTYLGG
                     SIQHFNQYIENPLDPGEVFGSETLVPILNILGEMGLVNYRSTIHLEFRTLGVTVGNVY
                     TFFRRPLHDFGLVGMYVFVFAVGAFFAIYYLVLRKKQVGFNLDIHTIIYSYVFYWIFL
                     SSIEQYSFTMISLYTLVFIVLVYFMAIFYWCTDFKRGKLIFKISDSSIKLKEE"
     gene            9079..10500
                     /locus_tag="VWZ68_000522"
     CDS             9079..10500
                     /locus_tag="VWZ68_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371601.1"
                     /translation="MNTKIKNIITSFSYVISSNLLIVLTSSLVVLIFPKIMGVTEYSY
                     WQLYIFYLTYIGFFHLGWIDGIYLKYGGLEYTNLDRKQFYSQMILFSSFLMLISLVLF
                     TLNLITVRDENARYIYNMAIISMIVTNLRTLYVYILQMTNRLKDSSVILISDRVLYVL
                     LLFMFIVFGWHEYKVMIWADILGRTFSLMLSFWICKDIVFQPLSKFILDFKESLDNIR
                     VGINLMLSNIASSMIIGIVRMGIQWNWNIETFGKVSLTLSISNLLMTFINAIGLVIFP
                     LIKRTKTENLPKIYSNLRNALMLVMFAILLFYYPLKFILDIWLPAYKDALVFMALIFP
                     MSVYEGKMALVINTYLKAMRMEKDILKINALVMLTSMVVTLVTTLLLNNLGLTVVSIV
                     ILLALRSIIAELILSKKLKISVKQDIALELLMTIIFISSSWYLSIWIAVIIYLLAYTL
                     YLYLKHKDIRMYIEYFKNHKKIS"
     gene            10564..11652
                     /gene="wecB"
                     /locus_tag="VWZ68_000523"
     CDS             10564..11652
                     /gene="wecB"
                     /locus_tag="VWZ68_000523"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HEU9371602.1"
                     /translation="MKKIMLVFGTRPEAIKMCSLVNELRKQEDMKTVVCVTGQHKEMV
                     SPVLDLFGVQPDYDLEIMKANQNLFSITISILEKIKPVLEKEQPDIVLVHGDTTTTYA
                     AALAAFYLGIKVGHVEAGLRTYNLQSPFPEEFNRQSTSIIANYHFAPTELAKENLIKE
                     GRNNIYVTGNTVIDALTTTVQKDYTHPDLDLNDGNRLILLTAHRRENLGEPMRHMFRA
                     VKRVLNEYDDVKVIYPIHKNPLVRETATEIFGDTERIQIIEPLDVLDFHNFMNHSYMI
                     LTDSGGVQEEAPSLGKPVLVMRDTTERPEGVAAGTLKLVGTDEETIYQNFKMLLDDPE
                     EYKKMSQASNPYGNGDASKQIVRILRGI"
     gene            11691..12560
                     /gene="rfbA"
                     /locus_tag="VWZ68_000524"
     CDS             11691..12560
                     /gene="rfbA"
                     /locus_tag="VWZ68_000524"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEU9371603.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGLKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKN
                     EYGQYLLRLIGEA"
     gene            12561..13157
                     /locus_tag="VWZ68_000525"
     CDS             12561..13157
                     /locus_tag="VWZ68_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEU9371604.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDLE"
     gene            13167..14216
                     /gene="rfbB"
                     /locus_tag="VWZ68_000526"
     CDS             13167..14216
                     /gene="rfbB"
                     /locus_tag="VWZ68_000526"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEU9371605.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            14282..15133
                     /gene="rfbD"
                     /locus_tag="VWZ68_000527"
     CDS             14282..15133
                     /gene="rfbD"
                     /locus_tag="VWZ68_000527"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEU9371606.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVARASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            15209..15643
                     /locus_tag="VWZ68_000528"
     CDS             15209..15643
                     /locus_tag="VWZ68_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9371607.1"
                     /translation="MLLVLVSLAHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSQLTYYWTF
                     LSGKAENQVITLYHHDQCRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            15716..15973
                     /locus_tag="VWZ68_000529"
     CDS             15716..15973
                     /locus_tag="VWZ68_000529"
                     /inference="COORDINATES: protein motif:HMM:NF015038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9371608.1"
                     /translation="MVNCEPLEAYRQLEEAELVGCWAHVRRKFFEVPPKQADKSSLGA
                     KGLAYCDQLFSLERDWEALPADERLQKRQEHLQPLMEDFFA"
     gene            16019..16165
                     /locus_tag="VWZ68_000530"
     CDS             16019..16165
                     /locus_tag="VWZ68_000530"
                     /inference="COORDINATES: protein motif:HMM:NF015038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9371609.1"
                     /translation="MEYSLKYEETFKTILKDGHLVLSNNLAERAIKSLVMGRSKRVQW
                     TLLA"
     gene            16236..16394
                     /locus_tag="VWZ68_000531"
     CDS             16236..16394
                     /locus_tag="VWZ68_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEU9371610.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            16593..18575
                     /locus_tag="VWZ68_000532"
     CDS             16593..18575
                     /locus_tag="VWZ68_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9371611.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDGYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVMAPVNEEFLNSKGDDFAKATDPNSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            18875..24193
                     /locus_tag="VWZ68_000533"
     CDS             18875..24193
                     /locus_tag="VWZ68_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU9371612.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQ
                     NDNAGKPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYD
                     KDGWFWEYKTPGNSTWYKGNRVAAPETGSINRLSITLKSDGQLNASNNDVNLFDTVTL
                     PAAVNDHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKV
                     TYDTIQSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKIN
                     ETTAEYLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLL
                     SSISFLGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVS
                     TDKLAAGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFP
                     EYTKELPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFG
                     SQAQNPFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDF
                     KTLIEKAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDA
                     AYDLAHGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRF
                     AIEWGHGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAA
                     NYPLLGGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDN
                     GSTYKWTPEMRVELVDANNNKVVVTRKSNDVNSPQYRKRTVTLNGRVIQDGSAYLTPW
                     NWDANGKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVK
                     DGKITLDLLANQPYVFYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEI
                     VKSQGANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKE
                     VTTYTNKSLALNYVKAYAHNTRRDNATVDNTSYFQNMYAFFTTGSDVSNVTLTLSREA
                     GDQATYFDEIRTFENNSSMYGENHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRT
                     HLSEKHDPYTQRGWNGKKVDDVIDGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYR
                     VTFEYEAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTG
                     AETGDTWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALK
                     NYLPTVAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTA
                     LVADDFASLTAPAQAQEGLANAFDGNVSSLWHTSWGGGDVGKPATMVLKEPTEITGLR
                     YVPRGSGSNGNLRDVKLVVTDESGKEHTFTATDWPNNNKPKDIDFGKTIKAKKIVLTG
                     TKTYGDGGDKYQSAAELIFTRPQVAETPLDLSGYEAALVKAQKLTDKDNQEEVASVQA
                     SMKYATDNHLLTERMMEYFADYLNQLKDSATKPDAPTVEKPEFKLRSLASEQGKTPDY
                     KQEIARPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(24360..26519)
                     /locus_tag="VWZ68_000534"
     CDS             complement(24360..26519)
                     /locus_tag="VWZ68_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEU9371613.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(26516..27112)
                     /gene="recU"
                     /locus_tag="VWZ68_000535"
     CDS             complement(26516..27112)
                     /gene="recU"
                     /locus_tag="VWZ68_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEU9371614.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            27178..27705
                     /locus_tag="VWZ68_000536"
     CDS             27178..27705
                     /locus_tag="VWZ68_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEU9371615.1"
                     /translation="MATALVLGYSTFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            27775..28104
                     /gene="gpsB"
                     /locus_tag="VWZ68_000537"
     CDS             27775..28104
                     /gene="gpsB"
                     /locus_tag="VWZ68_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEU9371616.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            28125..28505
                     /gene="rnpB"
                     /locus_tag="VWZ68_000538"
     ncRNA           28125..28505
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VWZ68_000538"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            28590..29747
                     /locus_tag="VWZ68_000539"
     CDS             28590..29747
                     /locus_tag="VWZ68_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEU9371617.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARLPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFDEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            29760..31154
                     /gene="mapZ"
                     /locus_tag="VWZ68_000540"
     CDS             29760..31154
                     /gene="mapZ"
                     /locus_tag="VWZ68_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEU9371618.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            31230..32654
                     /gene="gndA"
                     /locus_tag="VWZ68_000541"
     CDS             31230..32654
                     /gene="gndA"
                     /locus_tag="VWZ68_000541"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEU9371619.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            32666..33355
                     /locus_tag="VWZ68_000542"
     CDS             32666..33355
                     /locus_tag="VWZ68_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9371620.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            33453..34415
                     /gene="cbpC"
                     /locus_tag="VWZ68_000543"
     CDS             33453..34415
                     /gene="cbpC"
                     /locus_tag="VWZ68_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEU9371621.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLRSSGAMA
                     TGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLDPSN
                     GDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            34434..35432
                     /gene="cbpJ"
                     /locus_tag="VWZ68_000544"
     CDS             34434..35432
                     /gene="cbpJ"
                     /locus_tag="VWZ68_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEU9371622.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKELEIKTQDSVGRKYGEKRENSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYIGGERRAGWINDASAWYYLDPATGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(35550..36782)
                     /locus_tag="VWZ68_000545"
     CDS             complement(35550..36782)
                     /locus_tag="VWZ68_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9371623.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEIVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTLFLVLSPFSLI
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(36941..37411)
                     /locus_tag="VWZ68_000546"
     CDS             complement(36941..37411)
                     /locus_tag="VWZ68_000546"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371624.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCGIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            complement(37311..37649)
                     /locus_tag="VWZ68_000547"
     CDS             complement(37311..37649)
                     /locus_tag="VWZ68_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
                     /protein_id="HEU9371625.1"
                     /translation="MTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANV
                     TAKKLIENYDTLEEIDFALGKSGVLLSLIKYYQFTNDNTLKTFIHNSIWGNLSLFPTK
                     RYSQRKHFRL"
     gene            38312..38590
                     /locus_tag="VWZ68_000548"
     CDS             38312..38590
                     /locus_tag="VWZ68_000548"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9371626.1"
                     /translation="MIRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSAQVPWQ"
     gene            38765..39643
                     /gene="mvk"
                     /locus_tag="VWZ68_000549"
     CDS             38765..39643
                     /gene="mvk"
                     /locus_tag="VWZ68_000549"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEU9371627.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            39625..40578
                     /gene="mvaD"
                     /locus_tag="VWZ68_000550"
     CDS             39625..40578
                     /gene="mvaD"
                     /locus_tag="VWZ68_000550"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEU9371628.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            40565..41572
                     /locus_tag="VWZ68_000551"
     CDS             40565..41572
                     /locus_tag="VWZ68_000551"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEU9371629.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAESTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            41556..42566
                     /locus_tag="VWZ68_000552"
     CDS             41556..42566
                     /locus_tag="VWZ68_000552"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEU9371630.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            42644..43342
                     /locus_tag="VWZ68_000553"
     CDS             42644..43342
                     /locus_tag="VWZ68_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEU9371631.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMKQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            43339..44334
                     /locus_tag="VWZ68_000554"
     CDS             43339..44334
                     /locus_tag="VWZ68_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9371632.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDQDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            44348..44980
                     /locus_tag="VWZ68_000555"
     CDS             44348..44980
                     /locus_tag="VWZ68_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9371633.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            44981..45223
                     /locus_tag="VWZ68_000556"
     CDS             44981..45223
                     /locus_tag="VWZ68_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU9371634.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRSLENTNMWLLTI"
     gene            45148..45459
                     /locus_tag="VWZ68_000557"
     CDS             45148..45459
                     /locus_tag="VWZ68_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU9371635.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLRLT
                     S"
     gene            45484..45750
                     /locus_tag="VWZ68_000558"
                     /pseudo
     CDS             45484..45750
                     /locus_tag="VWZ68_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            45900..46139
                     /locus_tag="VWZ68_000559"
     CDS             45900..46139
                     /locus_tag="VWZ68_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371636.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            46220..47041
                     /gene="cbpG"
                     /locus_tag="VWZ68_000560"
     CDS             46220..47041
                     /gene="cbpG"
                     /locus_tag="VWZ68_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEU9371637.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            47060..48082
                     /gene="cbpF"
                     /locus_tag="VWZ68_000561"
                     /pseudo
     CDS             47060..48082
                     /gene="cbpF"
                     /locus_tag="VWZ68_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
     gene            complement(48210..48823)
                     /locus_tag="VWZ68_000562"
                     /pseudo
     CDS             complement(48210..48823)
                     /locus_tag="VWZ68_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        15229 a         8300 c        10714 g        14580 t
ORIGIN      
        1 tttcctttct gttgataggc tagtagcaga cgattgattt gtctttcaga aagattgagt
       61 tcgacacagg cccgtttctt tgttttcttt ccttgggcta tagcttttat cacaagatat
      121 tttttcgttt cattcatatt cagttggatc cttttcatat gactattcta ccaaatggga
      181 cattttcacg ttcgatttac taaagacatt atcacattcg aattacatta aagatgcaga
      241 tagtaaaaaa aatgtagaca ttaccgtaaa aaagtgatat aatcgtatga tgttcaaggt
      301 ataggtgtta atcatgagta gacgttttaa aaaatcacgt tcacagaaag tgaagcgaag
      361 tgttaatatc gttttgctga ctatttattt attgttagtt tgttttttat tgttcttaat
      421 ctttaagtac aatatccttg cttttagata tcttaaccta gtgataactg cgttagtcct
      481 actagttgcc ttgctagggc tactcttgat tatctataaa aaagctgaaa agtttactat
      541 ttttctgttg gtgttctcta tccttgtcag ctctgtgtcg ctctttgcag tacagcagtt
      601 tgttggactg actaatcgtt taaatgcgac ttctaattac tcagaatatt caatcagtgt
      661 cgctgtttta gcagatagtg atatcgaaaa tgttacgcaa ctgacgagtg tgacagcacc
      721 gactgggact gataatgaaa atattcaaaa actactagct gatattaagt caagtcagaa
      781 taccgatttg acggtcaacc agagttcgtc ttacttggca gtttacaaga gtttgattgc
      841 aggggagact aaggccattg tcctaaatag tgtctttgaa aacatcatcg agtcagagta
      901 tccagactac gcatcgaaga taaaaaagat ttataccaag ggattcacta aaaaagtaga
      961 agctcctaag acgtctaaga atcagtcttt caatatctat gttagtggaa ttgacaccta
     1021 tggtcctatt agttcggtgt cgcgatcaga tgtcaatatc ctgatgactg tcaatcgaga
     1081 taccaagaaa atcctcttga ccacaacgcc acgtgatgcc tatgtaccaa tcgcagatgg
     1141 tggaaataat caaaaagata aattaaccca tgcaggcatt tatggagttg attcgtccat
     1201 tcacacctta gaaaatctct atggagtgga tatcaattac tatgtgcgat tgaacttcac
     1261 ttctttcttg aaaatgattg acttattggg aggggtagat gttcataatg atcaagagtt
     1321 ttcagctcta catgggaagt tccatttccc agtagggaat gtccacctag actctgagca
     1381 ggctctaggt tttgtacgtg aacgctactc actagccgat ggagaccgtg atcgtggtcg
     1441 caaccaacaa aaggtcattg tagcaattat tcagaagtta acttctacag aggttttgaa
     1501 aaactatagt agtattcttc aaggattgca ggattctctt caaacaaata tgccgattga
     1561 gactatgata gatttagtga atactcagtt ggaaagtggg gggaattata aagtaaattc
     1621 tcaagattta aaagggacag gtcggatgga tcttccttct tatgcaatgc cagacagtaa
     1681 cctctatgtg atggaaatag atgatagtag tttagctgta gttaaagcag ctatacagga
     1741 tgtgatggag ggtagatgaa atgatagaca tccattcgca tatcgttttt gatgtagatg
     1801 acggtcccaa gtcaagagag gaaagcaagg ctctcttggc agaatcctac aggcaggggg
     1861 tgcgaaccat tgtctctacc tctcaccgtc gcaagggcat gtttgaaact ccggaagaga
     1921 agatagcaga aaactttctt caggttcggg aaattgcaaa agaagtggca gatgatttag
     1981 tcattgctta tggcgcagag atatactata ctctggatgc tctagaaaag ctagaaaaaa
     2041 aagaaattcc tacccttaat gatagtcgtt atgccttgat tgagtttagc atgcatactt
     2101 cctatcgtca gattcatacg ggattgagca atattttgat gttgggaatc acgccagtaa
     2161 ttgctcatat tgaacgttat gatgctttag agaataacga aaaacgtgtt cgtgaactga
     2221 ttgatatggg gtgctatact cagataaata gttatcatgt ttcaaaacct aagttctttg
     2281 gtgaaaaata taaattcatg aaaaagagag ctcggtattt tttggaacgt gatttagttc
     2341 atgtagttgc aagtgacatg cacaatttag acagtagacc tccatatatg caacaggcat
     2401 atgatatcat tgctaagaaa tatggagcga aaaaagtaaa agaacttttt gtagataatc
     2461 ccagaaaaat tataatggat caattaattt aggagaaaat atgaaggaac aaaacacttt
     2521 ggaaatcgat gtattgcaac tattcagagc tttatggaaa agaaagttgg tcattttatt
     2581 agtggcaatt ataacttctt cagttgcttt tgcctacagt acttttgtta tcaaacctga
     2641 gtttactagt atgactcgga tttatgtagt taaccgtaat cagggagaga agtctggttt
     2701 aaccaatcaa gacttgcagg caggatcatc cttggttaaa gactatcgtg aaattatcct
     2761 atcgcaggat gttttggagg aagttgtttc tgatttgaaa ctagatttga cgccaaaaga
     2821 tttggctaat aaaattaaag taacagtacc agttgatacc cgtattgtct ctgtttcagt
     2881 tagtgatcga gttcctgaag aggcaagccg tatcgctaac tctttgagag aagtagctgc
     2941 tcaaaaaatt atcagtatta ctcgtgtttc tgatgtgaca acactggagg aggcaagacc
     3001 ggcgacatca ccgtcttcgc caaatattaa acgcagtaca ctaattggtt ttttggcagg
     3061 agtgattgga actagtgtta tagttcttat tcttgaactt ttggacactc gtgtgaaacg
     3121 tccgaaagat atcgaagata cactgcatat gacacttttg ggaattgtac caaacttgaa
     3181 taagttgaaa taggagagag gaatgccgac attagaaata gcacaaaaaa aactggagtt
     3241 cgttaagaag gcagaagaat attacaatgc cttgtgtaca aatatacagt tgagcggaga
     3301 taaactaaaa gtaatttccg ttacttctgt taaccctgag gaaggaaaaa caactacttc
     3361 cgtaaatata gcaaggtcgt ttgcgcgtgc aggctataaa actcttttga tcgatggcga
     3421 tactcgaaat tcagttatgt caggattttt taaatctcgt gaaaaaatta cagggctaac
     3481 ggaattttta tctgggacag ctgatttatc tcacggttta tgtgatacaa atattgaaaa
     3541 tttatttgta gttcaatcgg gcactgtatc accaaaccct acagccttgt tacaaagtaa
     3601 aaattttaat gatatgattg aaacattgcg taaatatttt gattatatca ttgttgatac
     3661 agcacctatt ggaattgtta ttgatgcggc aattatcact caaaagtgtg atgcgtccat
     3721 cttggtaaca gcaacaggtg aggtgaataa acgtgatgtc caaaaagcga aacaacaatt
     3781 agaacaaaca gggaaactgt tcctaggagt tgttttgaat aaattagata tctcggttga
     3841 taagtatgga gtttacggtt tctatggaaa ttatggtaaa aaaataattt aggaaagatt
     3901 ctatggatga aaaaggattg aaaatttttt tggcagtatt acagagtatt attgtcattt
     3961 tattggttta ttttcttagc tttgttagag agacagaact tgaacgttct tcgatggtta
     4021 tactatacct tctccacttt tttgtattct attttagttc ctatggtaac aattttttta
     4081 aaagagggta cctagttgag tttaatagta ccataagata tatttttttc tttgcaatag
     4141 ctataagtgt attaaacttt tttatagcgg aacggtttag tatctctaga agaggaatgg
     4201 tatacttctt aactttagaa ggaatatcct tatacttgtt aaatttctta gtaaagaaat
     4261 attggaagca tgtgtttttt aatctaaaaa atagcaagaa aattttactg ttaacagtaa
     4321 cgaaaaatat ggaaaaagtt cttgataaat tgctagaatc tgatgaactt tcatggaaat
     4381 tggtagcagt aagtgttttg gataaatctg attttcaaca tgataaaata cctgtaattg
     4441 aaaaggaaaa aattattgaa tttgcaacgc atgaagttgt ggatgaggtg tttgtcaatc
     4501 ttccaggaga gagctacgat attggagaaa ttatctctag gtttgagaca atggggatag
     4561 atgtaactgt aaatcttaaa gcatttgata agaatttggg tcgcaataaa caaattcatg
     4621 agatggtagg attgaatgta gtcactttct ctacaaattt ttataaaact agtcatgtaa
     4681 ttgctaagcg gattattgat atcatgggtg cattggtagg gctgatacta tgtggtttag
     4741 tcagtattgt attggttcct ttgattcgaa aggatggggg ctctgctatt tttgctcaga
     4801 cgcgtatagg aaaaaatggt cgtcagttca ctttttataa gtttcgctct atgtgtgtag
     4861 atgccgaggc gaaaaaaaga gaactcatgg aacaaaatac catgcagggt ggaatgttta
     4921 aggtggacga tgatcctcgt atcacgaaaa ttggtcgttt tatacggaag actagcttgg
     4981 acgagttacc acagttttat aatgttctaa agggagatat gagtttggtt ggcacacggc
     5041 cacctacagt ggacgagtat gttcagtata cttcagaaca gaaacgtcga ctcagcttta
     5101 aacctggtat tacaggttta tggcaggtta gcggccgtag taaaataacc gattttgacg
     5161 atgttgtaaa attagatgtg gcttatattg ataattggac aatctggaaa gatattgaaa
     5221 ttttgcttaa aactgttaaa gttgtattta tgagagatgg agcgaagtga ggaatgaggg
     5281 atagaatcca acttttaggt gtaacaattg atttgcttac gatgaatgaa acgatagata
     5341 ttgtagaaca atatgtatta gaaaaaagac cactacactt gatgggggtg aatgctgata
     5401 aaattaatca gtgtcataca gatgagaaaa tcaaaaaaat cgttaatgag tcaggaatca
     5461 ttaatgcgga tggagcatca gttgttcttg caagtaagtt tttaggaacg cctgttcctg
     5521 aacgagtagc gggtattgat ttgatgcaat gtcttttaga gttgtcaaat aaaaaaggat
     5581 attcagttta cttttttgga gcaaaagaag aagttttgca agatatgctc aaagtattta
     5641 agagagatta tccaaatttg atagttattg gacacagaaa tggctatttt tctgaagagg
     5701 atgaacaagc tattcaagaa gatattcgtg aaaagaaccc tgattttgtg tttattggaa
     5761 ttacgtctcc taaaaaagaa tatattattc aaaaatttat ggatagtggc gtcaattcgg
     5821 tatttatggg agttggcggt agttttgatg tcttgtctgg tcatatccaa cgagcacctc
     5881 tatggatgca aaagtcaaat ttagagtggt tattccgtgt agctaatgag cctaaacgtc
     5941 tctttaaacg ttattttgta gggaatattt cattcatagg aagagtttta aaagcaaaaa
     6001 gaggtgtaaa atattgaacc agacagagat gattcgctta attcaaaaag ttgaattaga
     6061 tgctataaaa gagtttaaaa aaatctgtga agagaatgat atagattttt tcctccgcgg
     6121 tggtagtgta cttggtgcgg tcaaatacga cggctttatt ccatgggatg atgatatgga
     6181 tatcgctgtc cctcgtgaag catacgacaa acttccaagt gttttcaaag atagaattat
     6241 cgctgggaaa tatcaggttc ttacttatca atactgtgat acgttgcatt gctactttcc
     6301 tcgactattc cttttagaag atgaaagaaa acgtttgggc ttgccacgaa ataccaatct
     6361 aggattgcat ttgattgata tcattccttt agatggagca ccaaatcatt cggttttaag
     6421 aaagatttac tttggcaaag tatactggta tcgtttttta gcaagtttag gaacaactta
     6481 tgttggcgac catgtggata tgcattccac taagcaaaaa ctaattattg gtttctttaa
     6541 aaaactagga tttgcaaaac tatttcctca aaattctgta tacagacgct tggataatct
     6601 ctataaaaag tatgattgga aaaagcagaa gtatgcgggg actatcaatg cttctttatt
     6661 tgctaaagaa gttatgccag tagagatttg gggagaagga gtagagaagc cttttgagga
     6721 tactttcttt aaagttccaa cggagtatga tcgctacctg aaaagacttt acggagaaaa
     6781 ctatctttac gaagagccta gtgatgatga aaagaaatcg catttaggag gacactaatt
     6841 tgttttgtta tattattttg cattacaaag tcttagaaga aactatttct tgtgttaaat
     6901 ctataaaaga aggcaattat aatgcaaagc aaatcgttat tattgataat ttttctaata
     6961 atggtactgg tgaaaaacta caagagcttt atgaatcaga tttagaaatt gatgttttga
     7021 ttaaccatga aaatgctggt tttgctcgtg gaaataatgt ggcttatcaa tttgctaagg
     7081 aaaagtataa ccccgatttc atggttatca tgaataacga tattgagata gaaacagaaa
     7141 attttgaaaa aattgtgaca gatatctatc gtgaggaaaa attccatttg ctcgggccag
     7201 atatcttctc gactacttac caacttcacc aaaacccaaa acggttgaca cattatactt
     7261 atggagaagt taaagctcta aatgaaaaat ttaaaaaagg gagccaagtt agtctagctt
     7321 taaaaatcaa atgttggttg aaagctagta aagttcttcg aacagcaatc tatcaaaata
     7381 gacgtaaaaa aggatcagta gactatagaa aacaggtaga aaacccaatt cttcatggtt
     7441 cttttattgt atattcgaga gattttatcg aaaaagagga gtatgctttt aaccctaaca
     7501 ccttcttcta ctatgaaaca gagatattag attatgaagc tgaattaaaa ggatacaaga
     7561 gaatttatac acctaaaatt agagttttgc accatcaaaa tgttgcaact aatcaagttt
     7621 acacgaactt gttagaaaaa accttgtttt caaataaatg caactttaaa tccaccagtt
     7681 attttttgaa gttgatgaaa gaaaacgagg atgtttaaat gagttattta tttttacttt
     7741 gccttacatt attcttattg actatattct atttctttgc ttttattcaa gatttaattg
     7801 ctcctccagt agttatgtct gtaatgtttc taattagttc agtatttgca ctggttaatt
     7861 caaaaaactg gaatattgaa tatagtggaa tagcctatat tctcataatt agtggtatta
     7921 ttatattttc gcttccttta atggcattaa aatcacctaa ttttaatact gaggttaaga
     7981 ttgctgatcg attaattgat atccaatttt ggaaaattgc tctaactatt ataattgatc
     8041 tctttatttt gtatctttac aggaaggaaa tatataacct tgttcttagt aatggatata
     8101 cggggtcaaa tattcagtgg ttttttagaa atgcaacgag ttatgaaggt gaattgacag
     8161 tgcgaacttt tattcgagtt ctcattcgtg ttattgacgt atctgcttat atttttggat
     8221 atacttttat taataatttt cttatctatc gccataaacg ccctaaagac atattacttt
     8281 tagtaccttt attaatattt atttcaaaaa ctttaatatc aggaggccgg caagatatta
     8341 ttaaaattct gattgcctat gtaatcatga tgtatatcca acaaaaacgg aaagttggat
     8401 ggaatagagt catatctcat aaatatattc accttggatt tgttggttta atagcaggta
     8461 ttccagcatt ttactactct ttgtttttag ccggtcgttc aacgactagg acgctatttg
     8521 agagtgtttc gacctatcta ggaggctcaa ttcagcattt taatcagtat attgaaaatc
     8581 cattagatcc tggtgaagtt tttggcagtg aaacattggt gcctatatta aatatattag
     8641 gggaaatggg cctagttaat tatcgtagta caattcattt agaatttcgg acactaggag
     8701 ttactgtagg aaatgtttat acttttttta gaagaccctt gcatgatttt ggtctagttg
     8761 gtatgtatgt gtttgtcttt gctgtaggtg ctttttttgc tatttattat ttagttctga
     8821 gaaagaaaca ggttggtttt aatttggata ttcataccat tatttattct tatgtctttt
     8881 attggatttt tttatcatca atcgagcaat actcgttcac aatgattagt ctatatacac
     8941 ttgtatttat tgtgttggtt tactttatgg ctatctttta ctggtgtaca gattttaaaa
     9001 gaggaaaact gatttttaaa atttctgact caagtatcaa attaaaagaa gaataacaga
     9061 atgtatagga gagggtagat gaatactaaa attaaaaata taataactag tttttcttat
     9121 gttatttctt caaatctgct catagtttta acctcatcac tagttgtttt gatttttcct
     9181 aaaataatgg gggtaactga gtacagttac tggcaacttt atatttttta tctgacctat
     9241 atcggttttt tccacttggg ttggattgat gggatttatc tcaaatatgg tggcttagaa
     9301 tatacaaatt tagatagaaa acagttttat tctcagatga ttctattttc tagtttctta
     9361 atgctaatct cgctggtatt atttactttg aacctaataa ctgtaaggga tgaaaacgca
     9421 agatatattt ataatatggc tatcattagc atgatagtca caaacttaag aacactctat
     9481 gtttatatct tgcagatgac aaatcgcttg aaggatagtt cagtcattct aattagtgat
     9541 cgcgttttat atgtactcct tttattcatg tttattgtat ttggatggca tgagtacaag
     9601 gtcatgattt gggctgatat tctaggtcga acattttctc tcatgctttc cttctggatt
     9661 tgtaaagata ttgtgtttca gcctttgtca aaatttatct tagatttcaa ggagtccctt
     9721 gataatatcc gtgttggaat caatttaatg ctatctaaca ttgcgagtag catgattata
     9781 ggcattgttc gtatgggaat tcaatggaat tggaatattg aaacattcgg gaaagtgtca
     9841 ttaactttga gtatatctaa tttattaatg acttttatta atgccattgg attagttatc
     9901 tttcctttga taaagcgaac aaagactgag aatttaccta aaatttattc taatttaaga
     9961 aatgctttga tgttggttat gttcgcaatc ttgctcttct actatccttt aaaatttatt
    10021 cttgatattt ggcttcctgc ttataaggat gccttagttt tcatggccct aatttttcct
    10081 atgtcagttt atgaagggaa aatggctttg gtgataaata catatttaaa agcaatgaga
    10141 atggaaaaag acattctcaa aattaatgct ttggttatgt taactagtat ggtagtgaca
    10201 ttagtgacta ctctactact aaataatttg gggctgacag ttgtatctat agttatttta
    10261 cttgctttaa gaagtataat agctgaatta attttatcca aaaaactgaa gatatcagtc
    10321 aagcaagaca ttgctttaga gttacttatg acgattatat ttatttcttc aagttggtat
    10381 ctctctattt ggattgcagt aataatttat ttattggcgt atactttata tttgtattta
    10441 aagcacaaag atatcagaat gtatatagaa tactttaaaa atcataaaaa aatatcataa
    10501 aaattatata tcaatgaaat ggtagattac atttctacct ttttatccat ttaggaggaa
    10561 acgatgaaaa agataatgct agttttcggt acacgtccag aagcaataaa aatgtgttca
    10621 ttagtcaatg agttgagaaa acaggaagat atgaaaacag ttgtttgtgt aactggtcaa
    10681 cacaaggaga tggttagccc tgttttagat ttatttggag ttcaaccaga ctatgattta
    10741 gaaattatga aggctaatca aaacttgttc tctataacaa taagtatttt agaaaaaata
    10801 aaacctgtgt tagaaaaaga acaaccagat attgttttgg ttcacggtga tactactacg
    10861 acatatgcag cagctttagc ggcattttat ctaggaatta aagttggtca tgttgaagct
    10921 ggattacgaa cttacaacct gcaaagtcct ttcccagaag agttcaacag acaatcgact
    10981 tctattattg caaattatca ttttgctcct acagaattag ctaaagaaaa tctaataaaa
    11041 gagggtagaa ataatatcta tgttactgga aatacagtga ttgatgcact tacaactaca
    11101 gtacaaaagg attatacaca ccccgatcta gatttaaacg atggaaatcg cctcatctta
    11161 ttgactgctc atagacgcga aaatctcgga gaacctatga gacatatgtt tagagctgtt
    11221 aaacgagttt taaatgaata tgacgatgtt aaagtaattt atccaattca taaaaatcca
    11281 ttggtacggg aaacagctac agaaattttt ggagatacag aacgtattca gatcattgaa
    11341 cctttagatg ttcttgattt tcacaacttt atgaatcata gttatatgat tctaactgac
    11401 tcaggagggg ttcaagaaga ggcaccttcg ttaggaaagc ctgtattggt catgcgagat
    11461 acgacagaaa gacctgaagg agtagctgct ggaacgttga aattggttgg gactgatgag
    11521 gagactattt atcaaaactt taagatgctt ttagacgatc ccgaagaata taaaaaaatg
    11581 agtcaagcta gtaatcctta tggaaatggt gatgctagta aacagattgt tcgaatttta
    11641 cgtggaattt gagtgtgttc agataaagta atatagaaag gtaccctact atgaaaggta
    11701 ttattctagc aggtggttcg gggacacgtt tatatccttt gactcgcgct gcatcaaaac
    11761 aacttatgcc ggtttatgat aaaccgatga tttactaccc actttcaaca ttgatgttgg
    11821 ctgggattag ggatattttg attatttcca ctccacagga tttacatcga ttccaagagc
    11881 ttcttcaaga cggatctgag tttgggctca aactttctta tgcagagcaa ccaagtccag
    11941 atggtttggc acaagccttt atcattgggg aagagtttat ttctgatgat agcgttgcgc
    12001 tgatcttagg tgacaatatc tatcacggtt ctgggctttc caagatgcta caaaaggcag
    12061 cgagtaagga gtcgggagca actgtttttg gctaccatgt caaggatcca gagcgctttg
    12121 gtgtggttga gtttgatcag gatatgaagg ctatttctat tgaagaaaag ccagagcaac
    12181 ctcgttcaaa ctatgcagtt acaggtctct atttctatga taatgatgta gtagagattg
    12241 ccaagagtat taaaccaagt cctcgtggtg aactggaaat tacagatgta aacaaggctt
    12301 acctagatcg tggtgatttg tctgttgagc ttatgggacg tggctttgct tggctggata
    12361 ctggaactca tgaaagttta ctagaggctt cacagtacat cgaaacagtg caacggatgc
    12421 aaaatgttca ggtagcaaac ttagaagaaa ttgcttaccg tatgggctat atcagtcgag
    12481 aagatgtatt ggccttagcc caaccactta agaaaaatga atacggacag tatctgctcc
    12541 gtttgattgg agaagcatag atgacagata attttttcgg taagacgctt gcggcacgca
    12601 aggttgaagc tattccaggc atgttggagt ttgatatccc cgttcatgga gataaccgtg
    12661 gctggtttaa agaaaatttc caaaaggaaa aaatgcttcc acttggattt ccagagtctt
    12721 tctttgcaga aggaaaattg caaaacaatg tatccttctc acgtaaaaat gtccttcgag
    12781 gtctccacgc agagccttgg gataagtaca tctctgtagc agatggaggg aaagttctgg
    12841 gttcttgggt tgatctacgc gagggtgaaa cctttgggaa tacctatcag acagtgattg
    12901 atgcgagtaa gggaatcttt gttcctcgag gcgtagctaa tggctttcaa gttttatcag
    12961 atacagtgtc atatagctat ctggtcaatg attactgggc tcttgaactc aaacccaagt
    13021 atgcctttgt gaactacgct gatccaagcc ttggtattga atgggaaaat attgcagaag
    13081 cagaggtttc agaagcagac aaacatcatc cactacttaa ggatgtaaaa cctttgaaaa
    13141 aagaagattt ggaataagga aagaatatga ctgaatacaa aaatattatc gtgacaggtg
    13201 gagctggctt tatcggttct aactttgtcc attatgttta cgagaacttt ccagatgttc
    13261 atgtgacagt cctagataag ttgacttatg ctggaaaccg cgcgaatatt gaggaaattt
    13321 taggtaatcg tgttgagtta gttgttggtg acattgctga tgcggagttg gtagacaagt
    13381 tggctgctca agcagatgct atcgttcatt atgcagcgga aagccacaat gataattcgc
    13441 tcaatgatcc atcgccattt attcatacta acttcatcgg aacctatact cttttagaag
    13501 ctgctcgtaa gtatgatatt cgcttccacc atgtatcgac agatgaagtt tatggggatc
    13561 tccctttacg cgaagatttg ccaggtcatg gtgaaggacc aggtgagaaa tttactgctg
    13621 aaacaaaata caacccaagc tctccgtact catcaaccaa ggcagcctca gatttgattg
    13681 tcaaagcctg ggtgcgttct tttggagtca aggcaacgat ttccaactgt tcaaataact
    13741 acggtcctta tcaacatatc gaaaaattca tcccacgtca gattactaac atcctaagtg
    13801 gtatcaagcc aaaactttac ggtgaaggta agaacgttcg tgattggatt cataccaatg
    13861 accattcttc aggagtttgg acaatcttga caaaagggca aatcggtgaa acctacttga
    13921 ttggggctga tggtgagaag aacaataagg aagttttgga acttatcctt aaggaaatgg
    13981 gacaagctgc ggatgcctat gatcatgtga ctgaccgtgc aggacatgac cttcgctatg
    14041 cgattgatgc tagcaagctc cgtgatgagt tggggtggaa acctgaattt accaactttg
    14101 aagctgggct caaggcaaca atcaagtggt atacagataa ccaagaatgg tggaaagcag
    14161 agaaagaagc tgttgaagcc aattatgcta agactcagga gattattaca gtataaaaag
    14221 caggaaatag ctgcttttta ttgctatatt gggaagagtt acatattaga aaggtctaga
    14281 gatgatttta attacagggg caaatggcca attaggaacg gaacttcgct atttattgga
    14341 tgaacgtaat gaagaatacg tggcagtaga tgtggctgag atggacatta ccgatgcaga
    14401 aatggttgag aaagtttttg aagaggtgaa accgacttta gtctaccact gtgcagccta
    14461 caccgctgtt gatgcagcag aggatgaagg aaaagagttg gacttcgcca tcaatgtgac
    14521 ggggacaaaa aatgtcgcaa gagcatctga aaagcatggt gcaactctag tttatatttc
    14581 tacggactat gtctttgacg gtaagaaacc agttggacaa gagtgggaag ttgatgaccg
    14641 accagatcca cagacagaat atggacgcac taagcgtatg ggggaagagt tagttgagaa
    14701 gcatgtgtct aatttctata ttatccgtac tgcctgggta tttggaaatt atggcaaaaa
    14761 cttcgttttt accatgcaaa atcttgcgaa aactcataag actttaacag ttgtaaatga
    14821 ccagtacggt cgtccgactt ggactcgtac cttggctgag ttcatgacct acctagctga
    14881 aaatcgtaag gaatttggtt attatcattt gtcaaatgat gcgacagaag acacaacatg
    14941 gtatgatttt gcagttgaaa ttttgaaaga tacagatgtc gaagtcaagc cagtagattc
    15001 cagtcaattt ccagccaaag ctaaacgtcc gctaaactca acgatgagcc tggccaaagc
    15061 caaagctact ggatttgtta ttccaacttg gcaagatgca ttgcaagaat tttacaaaca
    15121 agaagtgaga taagtagtag aatgattttc tagtctaata aaagaggcag ataatgaact
    15181 ccaaaggagc ttaagatgta cgattatctt gttgttggtg ctggtctctt tggcgcatag
    15241 ctttggctca gtttctatta tcgctcacac catccatcag aagtttaatc tgaaggtacc
    15301 caattatcgc caagaagaag attgggctag gatgggttta ccaatcacac gtaaggaaat
    15361 ctctaattgg catatcaagg caagtcaata ctatttagag tccctttata accttttacg
    15421 agaaaagttg ttagaacaac ctcttcttca tgcggatgaa acctcttatc gggtcttaga
    15481 aagtgatagt cagctgacct actattggac ctttttgtct gggaaagctg agaatcaagt
    15541 aatcacgctt taccaccatg atcagtgtcg gagtggttcg gtagtgcaag aattcctagg
    15601 agattattct ggctatgtgc attgtgatat gttgcggcag taacttagga ctttagtcct
    15661 ctagttctgt ctatgcgata gcagtccaag gtttaggagc aaggcgacgc taagcttggt
    15721 aaactgcgaa ccgctagaag cttatcgtca actggaagaa gctgaacttg ttggatgttg
    15781 ggcgcatgtg agaaggaaat tttttgaagt gccccccaag caagcagata aatcatcctt
    15841 aggagctaaa ggtttagctt attgtgatca gttattttcc ttggaaagag actgggaggc
    15901 tttgccagct gatgaacgac tacagaaacg tcaagaacat ctccaacccc taatggaaga
    15961 cttctttgct tagtgccgtc gtcagtcagt tttatcgggt tcaaaactag gaagggcaat
    16021 tgaatacagc ctcaagtatg aagaaacctt taagaccatt ttaaaagacg gacatctggt
    16081 cctttccaat aatctagctg aacgcgccat taaatcattg gttatgggac ggagtaaaag
    16141 agtccagtgg actcttttag cctaagctaa attttaaaaa gcgagggtgg ttattttctc
    16201 aaagttttga aggagctaaa gcaagagcta ttattatgag cttattggaa acagctaaac
    16261 gtcatcaact aaatagtgag aaatatctat cctatcttct agaatgtctt ccaaacgagg
    16321 aaactctcgt aaacaaagag gttttagagg cctatttacc atggactaaa gttgtacaag
    16381 aaaagtgcaa ataagaaatc tccagattag gaactatccg tgagttcact aatctggaga
    16441 tttttcaata gacctcgtta ttgggcggtt acgatattca tattttttgc aaagatgttg
    16501 tttgaaaaat aattttcaaa aattctgaaa attctgttga catctttctg aaaagagtct
    16561 ataatggaga gaaagtttta aaggagaaaa tgatgaaaag ttcaaaacta cttgcccttg
    16621 cgggcgtgac attattggcg gcgactactt tagctgcatg ctctggatca ggttcaagca
    16681 ctaaaggtga gaagacattc tcatacattt atgagacaga ccctgataac ctcaactatt
    16741 tgacaactgc taaggctgcg acagcaaata ttaccagtaa cgtggttgat ggtttgctag
    16801 aaaatgatcg ctacgggaac tttgtgccgt ctatggctga ggattggtct gtatccaagg
    16861 atggattgac ttacacttat actatccgta aggatgcaaa atggtatact tctgaaggtg
    16921 aagaatacgc ggcagtcaaa gctcaagact ttgtaacagg actaaaatat gctgctgata
    16981 aaaaatcaga tgctctttac cttgttcaag aatcaatcaa aggattggat ggctatgtaa
    17041 aaggggaaat caaagatttc tcacaagtag gaattaaggc tctggatgaa cagacagttc
    17101 agtacacttt gaacaaacca gaaagcttct ggaattctaa gacaacaatg ggagtaatgg
    17161 ctccagttaa tgaagagttt ttgaattcaa aaggggatga ttttgccaaa gctacggatc
    17221 caaatagtct cttgtataac ggtccttatt tgttgaaatc cattgtgacc aaatcttctg
    17281 ttgaatttgc gaaaaatccg aactactggg ataaggacaa tgtgcatatt gacaaagtta
    17341 aattgtcatt ctgggatggt caagatacca gcaaacctgc agaaaacttt aaagatggta
    17401 gccttacagc agctcgtctc tatccaacaa gtgcaagttt cgcagagctt gagaagagta
    17461 tgaaggacaa tattgtctat actcaacaag actctattac gtatttagtt ggtacaaata
    17521 ttgaccgtca gtcctataaa tacacatcta agaccagcga cgaacaaaag gcatcgacta
    17581 aaaaggctct cttaaacaag gatttccgtc aggctattgc ctttggtttt gatcgtacag
    17641 cctatgcctc tcagttgaat ggacaaactg gagcaagcaa aatcttacgt aatatctttg
    17701 ttccaccaac atttgttcaa gcagatggta aaaactttgg cgatatggtc aaagagaaat
    17761 tggttactta tggggatgaa tggaaggatg ttaatcttgc agattctcag gatggtcttt
    17821 acaatccaga aaaagccaag gctgaatttg ctaaagctaa atcagcctta caagcagaag
    17881 gtgtgacttt cccaattcat ttggatatgc cagttgacca gacagcaact acaaaagttc
    17941 agcgcgtcca atctatgaaa caatccttgg aagcaacttt aggagctgat aatgtcatta
    18001 ttgatatcca acaactacaa aaagacgaag taaacaatat tacatatttt gctgaaaatg
    18061 ctgctggcga agactgggat ttatcagata atgtcggttg gggtccagac tttgccgatc
    18121 catcaaccta ccttgatatc atcaaaccat ctgtaggaga aagtactaaa acatatttag
    18181 ggtttgactc aggggaagat aatgtagctg ctaaaaaagt aggtctatat gactacgaaa
    18241 aattggttac tgaggctggt gatgaggcta cagatgttgc taaacgctat gataaatacg
    18301 ctgcagccca agcttggttg acagatagtg ctttgattat tccaactaca tctcgtacag
    18361 ggcgtccaat cttgtctaag atggtaccat ttacaatacc atttgcattg tcaggaaata
    18421 aaggtacaag tgaaccaatc ttatataaat acttggaact tcaagacaag gcagtcactg
    18481 tagatgaata ccaaaaagct caggaaaaat ggatgaaaga aaaagaagag tctaataaaa
    18541 aggctcaaga agatctcgca aaacatgtga aataactgtt gcaaaatata agaaaggatt
    18601 tagtatttct cttgaatgct gaatcctttt ttacatttgt aaagaaagat tctaaatgta
    18661 ctgaccccca aaagttggag cctctttttg tcagaataga gaaaattttt gttaatttta
    18721 cttgtttcct attgctttct cagttattat ttgttatatt aaaagtataa ttatttttat
    18781 ttatcagggt taagcattgc attttcagag gaaggagtat tttttaaaaa ggaaatgtaa
    18841 acgcttgctc aaaaatgaaa ggatttagaa gtttatgaat aaaggattat ttgaaaaacg
    18901 ttgtaaatat agtattcgga aattttcatt aggtgttgct tctgttatga ttggagctgc
    18961 attctttggg acaagtccgg ttcttgcaga tagcgtgcag tctggttcca cggcgaactt
    19021 accagctgat ttagctactg ctcttgcaac agcaaaagag aatgatgggc gtgattttga
    19081 agcgcctaag gtgggagaag accaaggttc tccagaagtt acagatggac ctaagacaga
    19141 agaagaacta ttagcacttg aaaaagaaaa accggctgaa gaaaaaccaa aagaggataa
    19201 acctgcagct gctaaacctg aaacccctaa gacggtaacc cctaagacgg taactcctga
    19261 atggcaaacg gtagagaaaa aagaacaaca gggaacagtc actatccgag aagaaaaagg
    19321 tgtccgctac aaccaactat cctcaactgc tcaaaatgat aacgcaggca aaccagccct
    19381 gtttgaaaag aagggcttga ccgttgatgc caatggaaat gcaactgttg atttaacctt
    19441 caaagaagat tctgaaaagg gcaaatcacg ctttggtgtc ttcttgaaat ttaaagatac
    19501 caataataat gtttttgtcg gttatgacaa ggatggctgg ttctgggaat acaaaactcc
    19561 aggtaatagc acatggtata aaggcaaccg tgttgctgct cctgaaacag gatcaataaa
    19621 ccgtctttct atcactctca agtcagacgg tcagctaaat gccagcaata acgatgtcaa
    19681 tctctttgac acagtgactc taccagctgc ggtcaatgac catcttaaaa atgagaagaa
    19741 gattcttctc aaggcgggct cttatgacga tgagcgaaca gttgttagcg ttaaaacgga
    19801 taaccaagag ggggtaaaaa cagaggatac ccctgctgaa aaagaaacag gtcctgaagt
    19861 tgatgatagc aaggtgactt atgacacgat tcagtctaag gtcctcaaag cagtgattga
    19921 ccaagccttc cctcgtgtca aggaatacac cttgaatgga catactttgc caggacaggt
    19981 gcaacagttc aaccaagtct ttatcaataa ccaccgaatc acccctgaag tcacttataa
    20041 gaaaatcaat gagacaacag cagagtactt gatgaagctt cgcgatgatg ctcacttaat
    20101 caatgcggaa atgacagtac gcttgcaagt tgtggacaat caattgcact ttgatgtgac
    20161 caagattgtc aaccacaatc aagtcactcc aggtcaaaag atcgatgacg aaagaaaact
    20221 actttcttct attagtttcc tcggcaatgc tttagtctct gtttctagtg atcaaactgg
    20281 tgctaagttt gatggggcaa ccatgtcaaa caatacacat gtcagcggag atgatcatat
    20341 cgatgtaacc aatccaatga aggatttggc taagggttac atgtatggat ttgtttctac
    20401 agataagctt gctgctggtg tttggagtaa ctctcaaaac agctatggtg gtggttcgaa
    20461 tgactggact cgtttgacag cttataaaga aacagtcgga aatgccaact atgtaggaat
    20521 ccacagctct gaatggcaat gggaaaaagc ttataagggc attgttttcc cagaatacac
    20581 gaaggaactt ccaagtgcta aggttgttat cactgaagat gccaatgcag acaagaaagt
    20641 tgattggcag gatggtgcca ttgcttatcg tagcattatg aacaaccctc aaggttggga
    20701 aaaagttaag gatatcacag cttaccgtat cgcgatgaac tttggttctc aagcacaaaa
    20761 tccattcctt atgaccttgg atggtatcaa gaaaatcaat ctccacacag atggtcttgg
    20821 gcaaggtgtt ctccttaaag gatatggtag tgaaggtcat gactctggtc acttgaacta
    20881 tgctgatatt ggtaagcgta tcggtggtgt cgaagacttc aagaccctaa ttgagaaggc
    20941 taagaaatat ggagctcatc taggtatcca tgttaacgct tcagaaactt atcctgagtc
    21001 taaatatttc aatgaaaaaa ttctccgtaa gaatccagat ggaagctata gctatggttg
    21061 gaactggcta gatcaaggta tcaacattga tgctgcctat gacctagctc atggtcgttt
    21121 ggcacgttgg gaagatttga agaaaaaact tggtgacggt ctcgacttta tctatgtgga
    21181 cgtttggggt aatggtcaat caggtgataa cggtgcctgg gctacccacg ttcttgctaa
    21241 agaaattaac aaacaaggct ggcgctttgc gatcgagtgg ggccatggtg gtgagtacga
    21301 ctctaccttc catcactggg cagctgactt gacctacggt ggctacacca ataaaggtat
    21361 caacagtgcc atcacccgct ttatccgtaa ccaccaaaaa gatgcttggg taggggacta
    21421 cagaagttat ggtggtgcag ccaactatcc actgctaggt ggctacagca tgaaagactt
    21481 tgaaggctgg caaggaagaa gtgactacaa tggctatgta actaacttat ttgcccatga
    21541 cgtcatgacc aagtacttcc aacacttcac tgtaagtaaa tgggaaaatg gtacaccggt
    21601 gactatgacc gataacggta gcacctataa atggactcca gaaatgcgag tggaattggt
    21661 agatgctaac aataataaag tagttgtaac tcgtaagtca aatgatgtca atagtccaca
    21721 atatcgcaaa cgtacagtaa cgctcaacgg acgtgtcatc caagatggtt cagcttactt
    21781 gactccttgg aactgggatg caaatggtaa gaaactttct actgataagg aaaagatgta
    21841 ctacttcaat acgcaggccg gtgcaacaac ttggaccctt ccaagtgatt gggcaaagag
    21901 caaggtttac ctttacaagc taactgacca aggtaagaca gaagagcaag aactaactgt
    21961 aaaagatggt aaaattaccc tagatcttct agcaaatcaa ccatacgttt tctatcgttc
    22021 gaaacaaacc aatcctgaaa tgtcatggag tgaaggcatg cacatctatg atcaaggatt
    22081 taatagcggt accttgaaac actggaccat ttcaggcgat gcttctaagg cagaaattgt
    22141 caagtctcaa ggggcaaacg atatgcttcg tattcaagga aacaaagaaa aagttagtct
    22201 cactcagaaa ttaactggtt tgaaaccaaa taccaagtat gccgtttatg tcggtgtcga
    22261 taaccgtagt aatgccaagg cgagcatcac tgtaaacact ggtgaaaaag aagtgactac
    22321 ttataccaat aagtctctcg ctctcaacta tgttaaggcc tacgcccaca atacacgtcg
    22381 tgacaatgct acagttgaca atacaagtta cttccaaaac atgtacgcct tctttacaac
    22441 tggatcggac gtatcaaatg ttactcttac tttaagtcgc gaagctggtg atcaagcaac
    22501 ttactttgat gaaattcgta cctttgaaaa caattcaagc atgtacggag aaaaccatga
    22561 tacaggtaaa ggcaccttca aacaagactt tgaaaatgtt gctcagggta tcttcccatt
    22621 cgtagtgggt ggtgtcgaag gtgttgaaga caaccgcact cacttgtctg aaaagcatga
    22681 tccatataca caacgtggtt ggaacggtaa gaaagttgat gatgttatcg atggaaattg
    22741 gtcactcaag accaatggac tggttagccg tcgtaacttg gtttaccaaa ccatcccaca
    22801 aaacttccgc tttgaagctg gtaagaccta ccgtgtaacc tttgaatacg aagcaggttc
    22861 agataatacc tatgcttttg tagtcggtaa gggagaattc cagtcaggtc gtcgtggcac
    22921 tcaagcaagc aacttagaaa tgcatgaatt gccaaatact tggacagatt ccaagaaagc
    22981 caagaaggca accttcctcg tgacaggtgc agaaacagga gatacttggg taggtatcta
    23041 ctcaactgga aatgcaagta atactcgtgg tgattctggt ggaaatgcca acttccgtgg
    23101 ttataacgac ttcatgatgg ataatcttca aatcgaagaa attaccctaa caggtaagat
    23161 gttgacagaa aatgctctga agaactactt gccaacggtt gccatgacta actacaccaa
    23221 agagtctatg gatgctttga aagaggcggt ctttaacctc agtcaggccg atgatgatat
    23281 cagtgtggaa gaagcgcgtg cagagattgc caagattgaa gctttgaaga atgctttggt
    23341 tcagaagaaa acggctttgg tagcagatga ctttgcaagt cttacagctc ctgctcaggc
    23401 tcaagaaggt cttgcaaatg cctttgatgg caatgtgtct agtctatggc atacatcatg
    23461 gggcggagga gatgtaggca agcctgcaac catggtcttg aaagaaccaa ctgaaatcac
    23521 tggacttcgt tatgttccac gtggatcagg ttcaaatggt aacttgcgag atgtgaaact
    23581 tgttgtgaca gatgagtctg gcaaggagca tacctttact gcaactgatt ggccaaataa
    23641 caacaaacca aaagatattg actttggtaa gacaatcaag gctaagaaaa ttgtccttac
    23701 tggtaccaag acatacggag atggtggaga taaataccaa tctgcagcgg aacttatctt
    23761 tactcgtcca caggtagcag aaacacctct tgacttgtca ggctatgaag cagctttggt
    23821 taaggctcag aaattaacag acaaagacaa tcaagaggaa gtagctagcg ttcaggcaag
    23881 catgaaatat gcgacggata accatctctt gacggaaaga atgatggaat actttgcaga
    23941 ttatctcaac caattaaaag attctgctac gaaaccagat gctccaactg tagagaaacc
    24001 tgagtttaaa cttagatctt tagcttccga gcaaggtaag acgccagatt ataagcaaga
    24061 aatagctaga ccagaaacac ctgaacaaat cttgccagca acaggtgaga gtcaatctga
    24121 cacagccctc ttcctagcaa gtgttagcct agccctatct gctctctttg tagtaaaaac
    24181 gaagaaagac tagtatttag taaaacctct taacaagatt acggaagcag tctctatctt
    24241 ttccaatgag gtttatagta cagaaaaagc ctgagaagat atcttctcag gcttttgtta
    24301 agcacataaa tacaatagtg ctatgaaaaa atcacccaga aaaatctgga tgataaatgt
    24361 tatggttgtg ctggttgagg attctgattt tgttgatcag gggttgtatt tgattgttgc
    24421 gtattattgt taggattggt agtcgtacta ttatttgtgc ttggagtggt tgagctagac
    24481 tgtgaagttg aactatctga tgatgagctt gaactttcag ttgatggggg ttgttgtgga
    24541 gcaggtgagc tccacgtaga acgagcacca tttttaaata cgaattctcc atttctgtag
    24601 agcccctctg gtatattcca atcctctgga ttgcttcctt cagacaggta ggtcatcata
    24661 gagcggtaaa ctttggcagc gaccgtaagg ccattgccta caagtggtgt cagacggtta
    24721 gaatagcctg tccatacagc cattgaatat ttacgcgtat agccagcaaa tagttcatca
    24781 ggtgctacaa attgagaggt cttgatgtgg ttttcaattt cctcgtctgt atagttagag
    24841 gttcctgttt taccagcctg agggagccaa gcaagatagg catttcgtcc agttccataa
    24901 ctcaagactg ttttcatcat gtcggtcatc atataggctg tcgtttcctt catggcacga
    24961 gttccgacat tagagaactc tttttcactc ccatcactaa agacgacttt atggatatac
    25021 attggtttat agtaagttcc accatttgca aaggcagcgt aagcagcagc catcttttca
    25081 ctacttgctc catatttttt gtctgattcg gttgtgttac ttgaaatggc atttgagtag
    25141 tgaatacttg ggtagtcgat tccgagacca tttaggaaag tcttggcgcg gttgagtccg
    25201 accttgttta gagtttccac ggctgggacg tttcgcgatt gttgcagggc gtattgcaag
    25261 gtgatgttgc caaagtagcc cctatcccag ttataaacag gggtatttgt cccagggtag
    25321 ttatagggct catcgtgaac gatagtagca gttgaatcgt agacaccgta ctccaaggca
    25381 ggagcatagt ctgtgatcgg tttcatagtt gatccccagt cgcggtttgt ttctactgct
    25441 tggttaattc cgaaggaaac attacttgac tgatggcgtg ctcctagctg ggcaatgact
    25501 ttaccgttag aaacatcaac aatggtagaa gcgacttgca attcatcgtc tggataggca
    25561 acgtattcgt ctgtattgta aatatcccac agatgttttt gagcttcttg gtctacattt
    25621 gtgtagacat ccatcccagt tgtgagcagg ttatagcctg tttcttcttc cacttgattg
    25681 atgacttcct tgaggtaatt atccatgtaa gcagggtaat tacttgctga tttgagactt
    25741 tgtagtccat cagtaattgg tgtattgact gctttctcat actgttcagc agagatgtag
    25801 ccttgatttt tcatttcaga taagaccaag tttcggcggt cttgggctgc ttctggatgt
    25861 gaataggggt catattggtt tggtgcctga ggcattccag ccagcaaggc taactgaggt
    25921 aaacttaaat tattgaggtc tttaccatag tagttttgag ctgctgtctg cattccatag
    25981 ttcccattag acatgtagac cttatttata tagtaggtca agatttcttg cttggttgct
    26041 ttttgttcta actgaatcgc taaccaagct tcctgagcct tacgagaaat agtctggtcg
    26101 gaagtcgaag ttgaaaagta agtcaactta atcaactgtt gggtgagagt tgatccacct
    26161 tggagggaat tgctttgcag attgcgcaag aaagctccca ggatacggat ggtatcaatc
    26221 cccctgtggt cgaagaagcg atggtcttcg atagaaacga ttgccttaac caaatctgtg
    26281 ggaatatcat tagcttgggc attgacgcgg cgttcagaac ccaagtcagc aatgagttga
    26341 tttttattgt cgtagatttt actagaagtt gttgcaacta gtttactctc ggataggcta
    26401 ggagccttgc taacgtagta gaaaaaaact cctccgccta agacaatggc tgcgataacc
    26461 aagcttaaga agctaatgct cagatacttg attaggcgca gaatcgttgg tttgttcatc
    26521 ttgttttacc acctaataaa tgttctttga taacattgag ataaggaatt tgagggaagg
    26581 caccagcctt gatttcatat ccatattctc gaatatattc aagtggcatt gatttttgtc
    26641 ccttatcttg atgatagaag cgaatcaaat cgaatgccgg caataagtag gtttcttgct
    26701 gagaagaaaa gtgaagaagg acaaagcaga ttccttgttg ggcaaggact tgttccatat
    26761 gctgaatctg atgtggatga aaatttttca tcggaatcgc acgtttttgt tttgtttcct
    26821 tgacttcaaa gtcgatgtaa tatccattat aaacgccaga atagtccgtc gttgaagctt
    26881 gtcgaaaata ggcttcaaca atcttggcac gacttcgttg tggatagtcc acttgtacga
    26941 tttgaatagg agttggtttc ttatgtataa cagccaagcc ctgagacaaa tagtagtcgt
    27001 tggtagcatt gatcatcttt tcaaaagaca ttcctcgatt tgcgaaattt ttgggttgag
    27061 aaagagatgt ttgtcttttt tgtgatgaaa ctttatgtgg atagttgacc ataattctcc
    27121 ttattggtac aataacatca ctttattata ccataatttg cacagaaagg gttaaaaatg
    27181 gctacagctt tggttttagg ctattctact tttgatttgg gtttattttc tgataaggat
    27241 cctcgtctta aattgattaa aaaagcgata cgtaaagatt tagaggctat ggcagcagat
    27301 ggggtgtctt ggcttgtgtt tacaggaagt ttgggttttg aatattgggt tttagaggtt
    27361 gctcaggaga tgaaaaccga atacggtttc cagttggcca ccatttttgc ttttgaaacc
    27421 catggggaaa attggaatga aggtaatcag atgaaactga gtcgctttaa gcaggtagac
    27481 tttgtcaaat atgcttatcc tcgctatgaa cacaaggggc agttaagaga ttaccagcag
    27541 tttttgctgg aaaacacgac tagttcctat cttttttatg atgaagaaaa tgaaacaaaa
    27601 ctagcttatt tttaccaaaa gatgaaaaat caagaggact attttataaa gagattaaca
    27661 tttgatcaat taaatgaact tgctgaaaat ttttccgaaa attgaagctt tgaccttgat
    27721 ttttgtttgc ctttttttat ataataatac tagcaagcga gaatggagag agacatggca
    27781 agtattattt tttcagcgaa agatattttt gaacaagagt ttggacgtga agtccgtggc
    27841 tataataaag tagaagttga cgagttttta gacgatgtca tcaaggacta tgaaacctat
    27901 gctgccttgg tcaagtcact tcgtcaggaa attgcggatt tgaaggaaga attaactcgt
    27961 aaaccgaaac cttcaccagt tcaagcagaa ccccttgaag cggcaattac aagttctatg
    28021 acgaattttg atattttgaa acgcctgaat agattggaaa aagaagtttt tggtaaacaa
    28081 attttagata actcagattt ttaagtagtt atttgagatg tgcaattttt ggataatcgc
    28141 gtgaggagaa ttgcttctca tgaggaaagt ccatgctagc acaggctgtg atgcctgtag
    28201 tgtttgtgct aggcgaaacc ataagcctag ggacgagaaa tcgttacggc agttgaaatg
    28261 gctaagtcct tggataggcc agagtaggct tgaaagtgcc acagtgacgg agtctttctg
    28321 gaaacagaga gagtggaacg cggtaaaccc ctcaagctag caacccaaat tttggtcggg
    28381 gcatggagta tgcggaaacg aacgtagtat tctgactgct atcagctaga gctgttagtg
    28441 gtagacagat gattatcgaa ggaagtggtc ctagtcactt ctggaacaaa acatggctta
    28501 tagaaaattg catataggtt ggggctgaga aattttctca acctcatttt ttaaagtgga
    28561 catatagaaa ggtcttgcaa gactgtaaca tgaaaaaaga atttaattta attgcaactg
    28621 tggcagcagg gcttgaggct gtcgttggtc gtgaagtgcg agagttgggc tacgattgtc
    28681 aggttgaaaa tggacgtgtt cgttttcaag gagacgtgag agctattatc gaaaccaacc
    28741 tttggcttcg ggcagcagat cgtatcaaaa ttatcgtagg aacgttccca gctaagactt
    28801 ttgaagagct atttcaggga gttttcgctt tagattggga aaattattta ccacttggag
    28861 ctcggttacc gatttcaaaa gctaaatgtg ttaagtccaa acttcacaat gagcccagtg
    28921 ttcaggctat ttctaagaaa gctgttgtca agaaattgca gaaacactat gctcgcccag
    28981 aaggggttcc tctgatggag aatggcccag agtttaagat tgaggtctct attctcaaag
    29041 atgtggcaac tgtcatgatt gatacgaccg ggtctagcct ctttaaacgt ggttatcgta
    29101 ccgaaaaagg tggcgctcct atcaaggaaa atatggcagc agccatttta caactttcta
    29161 actggtatcc agacaagcct ttgattgatc cgacctgtgg ttcggggact ttctgtattg
    29221 aggcagttat gattgctaga aagatggcgc caggtcttcg tcgctctttt gcatttgatg
    29281 aatggaactg gatcagcgat cgcttgattc aagaagtgcg cacagaagcg gctaaaaaag
    29341 tagaacgtaa gcttgagttg gatatcatgg gctgtgatat tgatgctcgc atggtggaaa
    29401 ttgctaaggc caatgctcag gcagctggtg ttgcaggaga tattactttt aagcagatgc
    29461 gcgtgcagga tttacgttcc gataaaatca atggagtaat catttccaat ccgccttatg
    29521 gtgaacgttt gtcagatgat gcaggagtga ccaagctcta tgctgagatg gggcaagtat
    29581 ttgcaccgct gaaaacttgg agcaaattta tcctgactag tgatgaagct tttgaaagca
    29641 agtatggtag ccaagcagat aagaagcgta agttatacaa cggaaccttg aaagtggatc
    29701 tatatcaata ttttggtcag cgtgtcaaac ggcaagaggt aaaatagaaa gggatactca
    29761 tgagtaaaaa aagacgaaat cgtcataaaa aagaaggtca agaaccgcaa tttgattttg
    29821 atgaagcaaa agagctaaca gttggtcaag ctattcgtaa aaatgaagaa gtggaagcag
    29881 gagtcttgcc tgaggattcc attttggaca agtatgttaa gcaacacaga gatgaaattg
    29941 aggcggataa gtttgcgact cgtcaataca aaaaagagga gttcgttgaa actcagagtc
    30001 tggatgattt aattcaagag atgcgtgagg ctgtagagaa gtcagaagct tcttcggagg
    30061 aagttccatc ttctgaagac atcttactac ccttgcctct ggacgatgag gagcaaggct
    30121 tggatcctct attgctagat gatgaaaatc caacagaaat gactgaagaa gtggaagagg
    30181 agcaaaacct ttctcgtctg gatcaagagg actcagaaaa gaaaagtaaa aaaggcttta
    30241 ttttgaccgt tttggcgctt gtatcagtaa ttatttgtgt cagtgcttat tatgtctatc
    30301 gtcaagtggc tcgttcgacc aaggaaattg aaacttctca atcaactaca gccaatcaat
    30361 cggatgtgga tgattttaat acactttatg acgcctttta cacaaatagc aataaaacgg
    30421 ctttgaaaaa tagccagttt gataaactga gtcaactcaa gactttactt gataagctgg
    30481 aaggtagtcg tgaacatacg cttgccaaat ctaaatatga tagtctagta acgcaaatca
    30541 aggccattca agatgtcaat gcacaatttg aaaaaccagc tattgtggat ggtgtgttgg
    30601 ataccaatgc caaagccaaa tcggatgcta aatttacgga tattaaaact ggaaatacgg
    30661 agcttgataa agtgctagat aaggctatca gtcttggtaa gagccagcaa acaagtactt
    30721 ctagctcaag ttcaagtcaa actagcagct caagttcaag tcaagcaagt tcaaatacga
    30781 ctagtgagcc aaaaccaagt agttcaaatg agactagaag tagtcgcagt gaagtcaata
    30841 tgggtctctc gagtgcaggg gttgctgttc aaagaagtgc cagtcgtgtt gcctataatc
    30901 agtctgctat tgatgatagt aataactctg cctgggattt tgcggatggt gttttggaac
    30961 aaattctagc aacttcacgt tcacgtggct atatcactgg agaccaatat atccttgaac
    31021 gtgtcaatat cgttaacggc aatggttatt acaacctcta taagccagat ggaacctatc
    31081 tctttaccct taactgtaag acaggctact ttgtcggaaa tggcgctggt catgcggatg
    31141 acttggacta ctaagcagtc gttacaaaat tctttctttt caaaagtaaa aatgataaaa
    31201 taaaacaaat gaaacaagag gagtgtcaaa tgacaaaagc taactttggt gtcgtaggta
    31261 tggccgtaat gggtcgtaac cttgccctta atattgaatc acgtggttac acagttgcta
    31321 tctacaaccg tagtaaagaa aaaacggaag atgtgattgc ttgccatcct gaaaagaatt
    31381 ttgtaccaag ctatgacgtt gaaagttttg taaactcaat cgaaaaacct cgtcgtatca
    31441 tgctgatggt tcaagctgga cctggtacag atgctactat ccaagccctt cttccacacc
    31501 ttgacaaagg tgatatcttg attgacggag gaaacacttt ctacaaagat accatccgtc
    31561 gtaatgaaga attggcaaac tcaggtatca actttatcgg tactggagtt tctggtggtg
    31621 aaaaaggtgc ccttgaaggt ccttctatca tgcctggtgg acaaaaagag gcctacgaat
    31681 tggtttcgga tgttcttgaa gaaatctcag ctaaagcacc agaagatggc aaaccatgtg
    31741 tgacttatat cggtcctgat ggagctggtc actatgtgaa aatggttcac aacggtatcg
    31801 agtacggtga tatgcaattg atcgcagaaa gctatgactt gatgcaacac ttgctaggcc
    31861 tttctgcaga ggatatggct gaaatcttta ctgagtggaa caagggtgaa ttggatagct
    31921 acttgatcga aatcacagct gatatcttga gccgtaaaga cgatgaagac caagatggac
    31981 caatcgtaga ctacatcctt gatgctgcag gtaacaaggg aactggtaaa tggacgagcc
    32041 aatcatctct tgaccttggt gtaccattgt cactgattac tgagtcagtg tttgcacgct
    32101 acatttcaac ttacaaagaa gaacgtgtac atgctagcaa ggtgcttcca aaaccagctg
    32161 ccttcaactt tgaaggagac aaggctgaat tgattgaaaa aatccgtcaa gccctttact
    32221 tctcaaaaat catttcatac gcacaaggat ttgctcaatt gcgtgtagcc tctaaagaaa
    32281 acaactggaa cttgccattt gcagatatcg catctatctg gcgtgatggc tgtatcatcc
    32341 gttctcgttt cttgcaaaag attacagatg cttacaaccg cgatgcagat cttgccaacc
    32401 ttcttttgga cgagtacttc ttggatgtta ctgctaagta tcaacaagca gtgcgtgata
    32461 tcgtagctct tgcggttcaa gctggtgtgc cagtgccaac tttctcagca gctattactt
    32521 actttgatag ctaccgttca gctgaccttc cggctaactt gatccaagca caacgtgact
    32581 actttggtgc tcacacttac caacgtaaag acaaagaagg aaccttccac tactcttggt
    32641 atgacgaaaa ataagtaggt cagccatggg gaaacggatt ttattacttg agaaagaacg
    32701 aaatctagct cattttttaa gtttggaact ccagaaagag cagtatcggg ttgatctggt
    32761 agaggagggg caaaaagccc tttccatggc tcttcagaca gactatgatt tgattttatt
    32821 gaacgttaat ctgggagata tgatggctca ggattttgca gaaaaattga gtcgaactaa
    32881 acctgcctca gtcatcatga ttttagatca ttgggaagac ttgcaagaag agctggaagt
    32941 tgttcagcgt tttgcagttt catacatcta taagccagtc tttatcgaaa atctggtagc
    33001 gcgtatttcg gcgatcttcc gaggtcggga cttcattgat caacactgca gtctgatgaa
    33061 agttccaagg acctaccgca atcttaggat agatgttgaa catcacacgg tttatcgtgg
    33121 tgaagagatg attgctctga cccgccgtga gtatgacctt ttggcgacac ttatgggaag
    33181 caagaaagta ttgactcgtg agcaattgtt ggaaagtgtt tggaagtatg aaagtgcgac
    33241 cgagacaaat atcgtagatg tctatatccg ctatctacgg agcaagcttg atgttaaagg
    33301 acaaaaaagc tacattaaaa ccgtgcgtgg tgttggttac accatgcaag aatagaaaag
    33361 cagttgcagt tgtgtaactg cttttttgag gagtttttat atattgacat gcagtcgtgt
    33421 ctttgctaca atcgttttag gaggatatat aaatgaaact tttgaaaaaa atgatgcaag
    33481 ttctactagc agtctttttc tttggtttgc tagctacaaa tacggtattt gcgaatacca
    33541 caggtggccg atttgttgat aaggataata gaaaatatta tgtaaaagat gatcataaag
    33601 caatctattg gcataaaata gacggtaaaa cttactattt tggtgatatt ggagagatgg
    33661 ttgtcggttg gcaatactta gaaattcctg gaacaggtta tcgtgatgat ttatttgata
    33721 atcgtccagt cttcgaaatt ggccttcagg agaagtggta ctattttgga caagatggtg
    33781 ctttgctaga acaaacagat aaacaagtac tagaggcaaa aacgtctgaa aatacaggaa
    33841 aagtatacgg tgaacaatat cctctatctg ctgaaaagag aacttattat tttgataata
    33901 attatgctgt aaagacaggc tggatttatg aagacggcaa ttggtattat ttaaataagc
    33961 taggaaattt tggtgatgat tcttacaatc cactaccaat tggtgaagtt gctaagggtt
    34021 ggactcaaga ttttcatgtt actattgaca ttgatagaag caaacctgct ccatggtact
    34081 acctccgttc ctcaggagca atggccactg gctggtatca ggaaggtacc acttggtatt
    34141 atttagacca gccaaatggc gatatgaaaa caggttggca aaaccttggg aacaaatggt
    34201 actatctccg ttcctcagga gctatggcaa ctggttggta tcaagatggt tcaacttggt
    34261 actatttaga tccttctaat ggagatatga aaataggttg gacaaaagta aatggaaaat
    34321 ggtattatct caattcaaat ggagcaatgg ttacaggtag tcaaactatc gatggtaaag
    34381 tttataactt cgcttcatct ggtgagtgga tttaatgttg gaggatatat aaaatgaagc
    34441 ttttgaaaaa aactatgcaa gctggactaa cagtaatttt ctttggtttg ctagctacga
    34501 atacagtatt tgcagataac tctgaaggat ggcagtttgt ccaagaaaac ggtagaacct
    34561 attacaaaaa gggggacctc aaagaaacct actggcgagt gattgatggt aagtactatt
    34621 attttgattc tctatctgga gagatggttg tcggctggca atatatcccg tttccatcta
    34681 aaggtagtac aattggtcct tacccaaatg gtatcagatt agaaggtttt ccaaagtcag
    34741 agtggtacta ctttgataaa aatggagtgc tacaagagtt tgttggttgg aaagaattag
    34801 agattaaaac tcaagacagt gttggaagaa agtatgggga aaaacgtgaa aattcagaag
    34861 ataaagaaga gaagcgttat tacacgaact attactttaa tcaaaatcat tctttagaga
    34921 caggttggct ttatgatcag tctaactggt attatctagc taaaacagaa attaatggag
    34981 aaaactatat tggtggtgaa agacgtgcag gttggataaa tgatgcttca gcttggtact
    35041 acctagatcc agcaactggt attatgcaaa caggttggca atatctaggt aataagtggt
    35101 actacctccg ttcctcagga gcaatggcca ctggctggta tcaggaaggt accacttggt
    35161 attatttaga ccacccaaat ggcgatatga aaacaggttg gcaaaacctt gggaacaaat
    35221 ggtactatct ccgttcatca ggagctatgg caactggttg gtatcaagat ggttcaactt
    35281 ggtactacct aaatgcaggt aatggagaca tgaagacagg ttggttccag gtcaatggca
    35341 actggtacta tgcttatagc tcaggtgctt tggcagtgaa tacgaccgta gatggctatt
    35401 ctgtcaacta taatggcgaa tgggttcggt aatgacaggg cgcttataat tatattagaa
    35461 cactcgctta atcaaagaag tgactttgtt gtacttgacc tgacgattgg ggagattaaa
    35521 agcatgtgaa atctacacat gctttttcgt tagttatgag tgttgaactt gactaaccat
    35581 tgacaaaaga taagagcaat caaaataaga tacaaaaata tcaatgctaa ctgcaccgaa
    35641 acgcccgatg ctatggatag ggctaatagg gagagcaggg acggggcgag aatgtctact
    35701 gtgctcagag cagagcccac cgtccccatc ttgtcactgg ggatatgggc aaagacagct
    35761 gcttgtaggc gagggctgag aatgccgata atcgtagaac tgatgaaact ggtcacgaaa
    35821 attacgatat aggcttgaca aaggatacta gttattagag ccaataggga aatctcacag
    35881 aaaaccaaga ggtgcgtgaa acggatattt ttaaatagat tactgctggt catattgcca
    35941 aggatagctc cacaagacat gatgatggag agcagggcga agagttgccc aatgctcagt
    36001 tgtgctagtg tctgttggat gaagcggagg gcaatcagcc gaggggacac atccaagatg
    36061 gcaatcatac tggtcgtcag aaacagtagt atgacggtat cttttaacct caggagcaca
    36121 gccagcgact gtttaagatg ttgaaaatat ttcttaaaac tcagtgctgt atgtgacatt
    36181 tcaatccttt tttcaacctc atacaaggta tgtcgaataa catacaggcc caaaaaggca
    36241 atgacaaaag tcagagtgtt gataagggaa atagtttgaa tactcataac attgataagg
    36301 aatgcgccag ctagattggc gacaatgcgg acaaccctca tcagagactg cctgaacccc
    36361 atggcatcat gcaggtcgtc cttaattaca ctgatgtaga gggcgttcat catgtaggca
    36421 gacaggtagc tcaaggtgtc agagatgagg ttgatgatga caatcataat gactgaaatt
    36481 aatgaaaagg gcgacaagac gagaaatagt gtcaaaatag cgtagagcag gattttgatt
    36541 ttggcaatac agagtgcgtg tttgactcta ttttcttgaa aatctcctag aatcccgaga
    36601 aagagttgcg atagtagggg aactatctct gaaatggaaa tcagtaaaat cgctagcgga
    36661 gcgaaattgt actgagccac ataattgata atggcgaggt agaaaatact gtcgccgaat
    36721 gatgaaaaac agctgtttag cagcaactgt ctatatatgt tgtttgtcca aaataatttc
    36781 atacttttct ccttatgtct gcacatcgaa tgggaattta ttatttaata gacaccaata
    36841 taccccctgc ttcctattcc gaagtcaaac aaatctgctt taccactatc tccttgaaac
    36901 atcagtaaac cgtgatcatc tcgttcagaa catgctaaaa ttacctgttg gattttttca
    36961 tcagtaattt gttttgattg tagacagtgg tttgtagtaa gctagttatt ccgtggcaat
    37021 atcctgtcat catttttaga tgatggttaa aaacaaattc ttgatattta ctaataatat
    37081 ctttgtttcc gtcacaatcg tacatacaaa gatataagat tattccggaa attccttcgc
    37141 accaagaaag ttgtaaattt cctaaatttt cagtattaga agtaactttt tctaataatt
    37201 tttttaattc agcatggaat gtatggagat cattatagaa catagaaggt tctaagactt
    37261 tagaataggc aaataaagca tatgcaattc cacaatatcc atgagcaaag ctatagtcta
    37321 aaatgctttc tttggctgta tctctttgta ggaaataatg ataaatttcc ccatatacta
    37381 ttgtggatga aagttttaag agtattgtca ttggtaaatt gatagtattt tattaatgat
    37441 aataggacac cagattttcc caatgcaaag tctatttcct ctagagtatc ataattctct
    37501 attaatttct tagcggtgac gtttgctaat tgtagatagt attgattttt actgatagaa
    37561 aataaatgta ggagtaacca tagatagcct gcatcaccaa atagcagtga gtattgatat
    37621 tcatatgtat gtgtcgttct aattgtcact gccttcttga tgatagagag tattttagaa
    37681 tccagttctg gggggtacaa tttatttaga ggaaacagta gtccagctat tccgtgttgg
    37741 aatgataaat tacttacgaa atttctaaat tctgttgaag aagtgatcct tccttcagaa
    37801 tttacagttt tatctagtaa aaattgtaga acactattac attctgtttt gtaatcatat
    37861 ttatgttcct ctattttttt aattttgact aaattatttg tttgacttaa atttagtaga
    37921 cattgtaacc aaaatagttg ctcatctgtg agctgacctt gagtatgtga tagttctagt
    37981 aattgaatag gatcctttag gtagattcaa tcaatctata acacaacaac ataataacac
    38041 ttttaggata acttatcaaa tattatagta aaatgaaata ataacaggac aaatcgatca
    38101 ggacagtcaa atcgatttct aaaaatgttt tagaagtaga ggtgtactat tctagtttca
    38161 atctactata gtatatattt ttacatcttg aattgtcaaa ttaagtgcat aagtttcccg
    38221 tagcatactt cataaggcgt tttccactta agaaattttc gtggtcgatt atttagaacc
    38281 tgtattcaca aaaaaatgtt aagctagagt tatgatacgc aaagcatatg atactgattt
    38341 aaacgatcaa gaatgggcga agattgaacc ctatttctcc aaacaccgca cctataaatg
    38401 gccgaaacga gtacttgtta atgagacttt gtacgtcact aaaacaggtt gtcaatggcg
    38461 catgctccct cacgactttc ctctttactt aatggtatgg agtttctttc gtcgttctat
    38521 gacgacaggt tggttccagg tcaatggcag atggtactac gcttatagcg ctcaggtgcc
    38581 ttggcagtga atacgaccgt agatggctat tctgtcaact ataatggcga atgggttcaa
    38641 taatgaaaga agcgattgtg aatggaaaca atcgcttttt ttgtgaaaat ataataaaat
    38701 agataggaaa gaattaatac ttgtatgaaa aataagacgt tttttcgtct agtaaaagga
    38761 aaaaatgaca aaaaaagttg gtgtcggtca ggcacatagt aagataattt taatagggga
    38821 acatgcggtc gtttacggtt atcctgccat ttccctgcct cttttggagg tggaggtgac
    38881 ctgtaaggta gttcctgcag agagtccttg gcgcctttat gaggaggata ccttgtccat
    38941 ggcggtttat gcctcactgg agtatttgaa tatcacagaa gcctgcattc gttgtgagat
    39001 tgactcggct atccctgaga aacgggggat gggttcgtca gcggctatca gcatagcggc
    39061 cattcgtgca gtatttgact actatcaggc tgatctgcct catgatgtac tagaaatctt
    39121 ggtcaatcga gctgaaatga ttgcccatat gaatcctagt ggtttggatg ctaagacctg
    39181 tcttagtgac caacctattc gctttatcaa gaacgtagga tttacagaac ttgagatgga
    39241 tttatccgcc tatttggtga ttgccgatac gggtgtttat ggtcatactc gtgaagccat
    39301 ccaagtggtt caaaataagg gcaaggatgc cctaccgttt ttgcatgcct tgggagaatt
    39361 aacccagcaa gcagaagttg cgatttcaca aaaagatgct gaaggactgg gacaaatcct
    39421 cagtcaagcg catttacatt taaaagaaat tggagtcagt agccctgagg cagacttttt
    39481 ggttgaaacg actcttagcc atggtgctct gggtgccaag atgagcggtg gtgggctagg
    39541 aggttgtatc atagccttgg taaccaattt gacacacgca caagaactag cagaaagatt
    39601 agaagagaaa ggagctgttc agacatggat agagagcctg taacagtacg ttcctacgca
    39661 aatattgcta ttatcaaata ttggggaaag aaaaaagaaa aagagatggt gcctgctact
    39721 agcagtattt ctctaacttt ggaaaatatg tatacagaga cgaccttgtc gcctttacca
    39781 gccaatgtaa cagctgacga attttacatc aatggtcagc tacaaaatga ggtcgagcat
    39841 gccaagatga gtaagattat tgaccgttat cgtccagctg gtgagggctt tgtccgtatc
    39901 gatactcaaa acaatatgcc tacggcagcg ggtctgtcct caagttctag tggtttgtcc
    39961 gccctggtca aggcttgtaa tgcttatttc aagcttggat tggatagaag tcagttggca
    40021 caggaagcca aatttgcctc aggttcttct tctcggagtt tttatggacc actaggagcc
    40081 tgggataagg atagtggaga aatttaccct gtagagacag acttgaaact agctatgatt
    40141 atgttggtgc tagaggacaa gaaaaaacca atctctagcc gtgacgggat gaaactttgt
    40201 gtggaaacct cgacgacttt cgacgactgg gttcgtcagt ctgagaagga ctatcaggat
    40261 atgctgattt atctcaagga aaatgatttt gccaagattg gagaattaac ggagaaaaat
    40321 gccctggcta tgcatgctac gacaaagact gctagtccag ccttttctta tctgacggat
    40381 gcctcttatg aggctatgga ctttgttcgc cagcttcgtg agaaaggaga ggcctgctac
    40441 tttaccatgg atgctggtcc caatgttaag gtcttctgtc aggagaaaga cttggagcat
    40501 ttatcagaaa ttttcggtca tcgttatcgc ttgattgtgt caaaaacaaa ggatttgagt
    40561 caagatgatt gctgttaaaa cttgcggaaa actctattgg gcaggtgaat atgctatttt
    40621 agagccaggg cagttagctt tgataaagga tattcccatc tatatgaggg ctgagattgc
    40681 tttttctgac agctaccgta tctattcaga tatgtttgat ttcgcagtgg acttaaggcc
    40741 taatcctgac tatagcttga ttcaagaaac gattgctttg atgggagact tcctcgctgt
    40801 tcgtggtcag aatttaagac ctttttctct agaaatctgt ggcaaaatgg aacgagaagg
    40861 gaaaaagttt ggtctaggtt ctagtggcag cgtcgttgtc ttggttgtca aggctttact
    40921 ggctctgtat gatgtttctg ttgatcagga gctcttgttc aagctgacta gcgctgtctt
    40981 gcttaagcga ggagacaatg gttccatggg cgaccttgcc tgtattgtgg cagaggattt
    41041 ggttctctac cagtcatttg atcgccagaa ggtggctgct tggttagaag aagaaaactt
    41101 ggcgacagtt ctggagcgtg attggggctt ttcaatttca caagtgaaac caactttaga
    41161 atgtgatttc ttagtgggat ggaccaagga agtggctgta tcgagtcaca tggtccagca
    41221 aatcaagcaa aatatcaatc aaaatttttt aagttcctca aaagaaacgg tggtttcttt
    41281 ggtcgaagcc ttggaacagg ggaaagccga aaaagttatc gagcaagtag aagtagccag
    41341 caagctttta gaaggcttga gtacagatat ttacacgcct ttgcttagac agttgaaaga
    41401 agccagtcaa gatttgcagg ccgttgccaa gagtagtggt gctggtggtg gtgactgtgg
    41461 catcgccctg agttttgatg cggaatcaac caaaacctta aaaaatcgtt gggccgatct
    41521 ggggattgag ctcttatatc aagaaaggat aggacatgac gacaaatcgt aaggacgagc
    41581 atatcctcta tgcccttgag cagaaaagtt cctataatag ctttgatgag gtggagctga
    41641 ttcattcttc cttgcctctt tacaatctgg atgaaatcga tctttcgaca gagtttgctg
    41701 gtcgaaagtg ggactttcct ttttatatca atgccatgac tggtggaagt aataagggaa
    41761 gagaaatcaa tcaaaagctg gctcaggtgg cggaatcctg tggtatttta tttgtaacgg
    41821 gttcttatag cgcagccctc aaaaatccaa cggatgattc tttttctgtc aagtctagtc
    41881 atcccaatct cctccttgga accaatattg gattggacaa acctgtcgag ttaggacttc
    41941 agactgtaga agagatgaat cctgttctat tgcaagtgca tgtcaatgtc atgcaggaat
    42001 tactcatgcc cgagggagaa aggaagttta gaagctggca atcgcatcta gcagattata
    42061 gcaagcaaat tcccgttcct attgtcctca aggaagtggg ctttggaatg gatgccaaga
    42121 caatcgaaag agcctatgaa ttcggtgttc gtacagtgga cctatcgggt cgtggtggca
    42181 ccagctttgc ctatatcgaa aaccgtcgta gtggccagcg tgattacctc aatcaatggg
    42241 gtcagtctac catgcaggcc cttctcaatg cccaagaatg gaaagataag gtcgaactct
    42301 tggttagtgg aggggttcgg aatccgctgg atatgattaa gtgcttggtt tttggtgcta
    42361 aggctgtggg attgtcacga accgttctgg aattggttga aacctacaca gttgaagaag
    42421 tgattggcat tgtccaaggc tggaaagcag atctacgctt gattatgtgt tcccttaact
    42481 gtgccaccat agcagatcta caaaaagtag actatcttct ttatggaaaa ttaaaagaag
    42541 caaaggatca gatgaaaaag gcgtaaccag cgcctttttt tccatcctca gactgaggtg
    42601 acttttttga attgtgataa aatagaaggg agaggatgaa cctatgagaa aatttaaaat
    42661 ctttttattt atcgaagcct gtcttctgac aggagctctg attttgatgg tatcagagca
    42721 tttttcgcgt tttctgctga tactattcct ctttttgctt ttgattcgct actacactgg
    42781 taaagaggga aataatcttc ttttagtagc ggcaaccatt ctcttctttt tcatcgttat
    42841 gctcaatcct tttgtgattc tagctatttt tgttgcggtt atctatagcc tctttcttct
    42901 ttacccgatg atgaagcagg aaaaagagca gaccaatttg gtttttgaag aggtcgtgac
    42961 ggttaagaag gagaaaaatc gttggtttgg aaatcttcat catttttcaa gctaccagac
    43021 ttgccaattc gatgatatca atctctttcg cttcatgggt aaggacacta ttcatctgga
    43081 gagggtcatc ttaaccaatc atgacaatgt cattatcctc agaaagatgg taggaacgac
    43141 caaaatcatc gtacctgtag atgtggaagt cagtctcagc gttaactgtc tctatgggga
    43201 tttgactttt ttcaaccagc ccaagcgagc cctccgcaat gaacactatc atcaagaaac
    43261 aaaagactat ctcaagagta acaagagtgt caagattttc ttgaccacta tgattggtga
    43321 tgtggaggtg gttagaggat gaaaaaacaa gcctatgtca ttattgctct cacctccttc
    43381 ctatttgtct tttttttctc ccacagcttg ctggaaatac ttgattttga ctggtctatc
    43441 tttttgcacg atgtcgaaaa aacagaaaaa tttgtctttt tattgttggt tttcagcatg
    43501 tccatgacct gtctcttagc cctgttttgg cgagggatcg aagagctttc tctaagaaaa
    43561 atgcaggcta atctcaagcg tttattggca gggcaagaag tagttcaggt tgtagatcaa
    43621 gatttggatg ccagtttcaa gtccttatca ggtaaactta accttttgac agaggctctt
    43681 caaaaagctg aaaatcatag ccttgctcag gaagaggaaa tcatcgagaa ggaacggaag
    43741 cgaattgctc gggatttgca cgatacagtc agtcaggagt tgtttgcggc ccacatgatt
    43801 ttatcgggta tcagtcagca ggctttgaaa ttggatagag aaaagatgca gacccagttg
    43861 cagagtgtca cagctatttt agaaacagcc cagaaggatt tgcgggtttt gctcttgcat
    43921 ttgcgaccag ttgaactgga gcagaagagc ttgatagaag ggattcaaat tctcttaaaa
    43981 gagcttgagg acaagagtga tcttagggtt agtctcaagc agaatatgac gaaattgcct
    44041 aagaaaatcg aggagcatat cttccgtatc ctgcaagagt tgattagcaa taccctccgc
    44101 catgcccagg catcttgcct agatgtctac ctctatcaga cagatgttga attgcaactg
    44161 aaggtggtgg acaatgggat tggtttccag ttagggagct tagacgactt gagttatgga
    44221 ctgcgaaata tcaaggagcg ggttgaagat atggcaggga cggttcagtt attaacagct
    44281 cccaagcaag ggctggcagt tgatatccgt attcccctgt tagataagga atgataaagg
    44341 agtaaagatg aaaattttac tagtagatga ccatgaaatg gtccgtttgg gtttgaaaag
    44401 ctactttgac ctccaagacg atgtagaagt tgtgggtgag gcgtccaacg ggtctcaagg
    44461 gattgacttg gccttggaac tgcgtccaga tgtcattgtc atggatattg tcatgcctga
    44521 gatgaatggg attgacgcga ccttagcaat ccttaaagaa tggcctgaag ccaagatttt
    44581 gattgtgacc tcttatttgg acaatgaaaa aatcatgcca gtcttagatg ctggtgccaa
    44641 aggctatatg ctcaagactt ctagtgcaga tgaattgctt catgccgtca gtaaggtagc
    44701 tgctggcgag ctggccattg agcaagaggt tagcaagaag gttgaatacc accgcaatca
    44761 tatggaactt catgaagaat tgactgcgcg tgagcgagat gttctccaac tcatcgccaa
    44821 gggctacgaa aatcagcgca tcgcagatga cctctttatc tctctcaaga cggtcaagac
    44881 ccacgtgtcc aatattcttg ccaaacttga agtcagcgat cgtacccagg cggctgtcta
    44941 tgcctttcag caccatttgg tggggcaaga ggagttttag atgagtttag cagatttact
    45001 tgaggagcta gaagcagcaa aagactctaa aaaagcaagg tccatggaag cctatatgcg
    45061 ccatcaattt tcttttctag gtattgcggt gcctgaaaga aataaactct ataaaaatat
    45121 tttccagaag cgaaaaaaac aaagattatc gattgggatt ttgcagacac ttgctgggaa
    45181 aaggagccta gaaaatacca atatgtggct gctaactatt tgaaagcaat gcagtcttat
    45241 ctaaaggaaa ccgatttgcc taagctagag cagttagtcg tgacaaaatc ctggtgggac
    45301 acggtagata tcctagatcg agtagtaggg agtttggtgt atgaacaccc tgaactagaa
    45361 gaaataatct taatactctt cgaaaatctc ttcaaaccac gtcagctcta tctgcaacct
    45421 caaaacagtg ttttgagcaa tctgcggcta acttcctagt ttgctctttg attttcattg
    45481 agtataaaat ggagcctatc agataatatc tggctgagac gtgtcgctat tgaccaccag
    45541 ttgttaagaa aagagaagac caatactcaa ttaatggaaa agattctact tcataacttg
    45601 aaccaaacag aattttttat caataaagcc attggctgga ttctgcgaaa ctactccaaa
    45661 acgaatccaa cttgggtaac atgctttatt gatgaaaaca aggaaagaat ggctgaactt
    45721 agtatcaaag aagcaagcaa gtacctctag cgtgattgaa aagcgcagtc attaattgaa
    45781 aagtttacct gtttatgtga taatggaggg tatttaaaga aggtggtaga tttcttgatt
    45841 ctatagtaga ttaagaaatt tagaatagta ggctataatt acattaggag gctacaataa
    45901 tgaagaaaac tgtttataaa aaattgggta tttcaattat tgcgagtact ttattggcta
    45961 gccagttatc gacagtatct gctttgagtg ttatttctag tacgggtgaa gaatatgagg
    46021 taagtgagac actagaaaaa ggtccaggat ctaatgattc ttcattatct gagatttcac
    46081 caacgtatgg ttcatactac caaaagcaat cagaagtatt atcggtaatg atgatttgat
    46141 taaaattgat aatactttac agtatccgta ttcgacttca gctatggttt tatctaagta
    46201 ttatggagta gccgatggaa tgaatgtaga agggagggga agtgcgaatt ttattaaaga
    46261 taatgtgtta attacagcgg ctcacaacta ctacagacat gactatggga aagaagcgga
    46321 tgatatttat gttcttccgg ctgttagtcc aagtcaagaa ctatttggaa agatcaaagt
    46381 aaaggaagtt cgttatttga aggaatttag aaatttaaat tctaaggatg caagggaata
    46441 tgacttggct ttattaattc tagaagagcc cattggtgca aaattaggga ctttgggtct
    46501 tcctactagt caaaaaaatt tgacaggaat aactgtgact atcacaggct atccatcata
    46561 taattttaaa attcatcaaa tgtatacaga taaaaaacaa gttttaagtg atgatggcat
    46621 gttcttggat taccaagttg atactttaga ggggtctagt ggatctacag tttatgatgc
    46681 tagtcaccgt gtagtaggag tgcatacttt aggagatgga gctaatcaaa ttaacagtgc
    46741 agttaaatta aatgaacgaa atttgccatt tatttattcg gttcttaaag gttactctct
    46801 tgaaggatgg aagaaaataa atggtagttg gtaccattat agacaacatg ataaacaaac
    46861 gggttggcag gagataaatg atacttggta ttatttagac agttccggta agatgcttac
    46921 agattggcaa aaagtaaatg gaaaatggta ttatctcaat tcaaatggag caatggttac
    46981 aggtagccaa actatcgatg gtaaagttta taacttcgct tcatctggtg agtggattta
    47041 atgttggagg atatataaaa tgaagctttt gaaaaaaatg atgcaagtcg cactagccac
    47101 atttttcttc ggtttgctag ggaccagtac agtatttgca gatgattctg aaggatggca
    47161 gtttgtccaa gaaaatggta gaacctacta caaaaagggg gatctaaaag aaacctactg
    47221 gagagtgata gatgggaagt actattattt tgatccttta tccggagaga tggttgtcgg
    47281 ctggcaatat atacctgctc cacacaaggg ggttacgatt ggtccttctc caagaataga
    47341 gatttctctt agaccagatt ggttttattt tggtcaagat ggtgtattac aagaatttgt
    47401 tggcaagcaa gttttagaag caaaaactgc tacgaatacc aacaaacatc atggggaaga
    47461 atatgatagc ccagcagaga aatgagtcta ttattttgaa gatcagcgta gttatcatac
    47521 tttaaaaact ggttggattt acgaagaggg tcattggtat tatttacaga aggatggtgg
    47581 ctttgattcg cgcatcaaca gattggcggt tggagagcta gcacgtggtt gggttaagga
    47641 ttcccctctt acctatgatg aagagaagct aaaagcagct ccatggtact atctagatcc
    47701 aacaactggc attatgcaaa ctggttggca atttctaggt aatagatggt actacctcca
    47761 ttcgtcagga gctatggcaa ctggctggta taaggaaggc tcaacttggt actatctaga
    47821 tgctgaaaat ggtgatatga gaactggctg gcaatacctt ggtaacaagt ggtactatct
    47881 ccgttcatca ggagctatgg caactggttg gtatcaggaa ggttcgactt ggtactatct
    47941 aaatgcaagt aatggagata tgaaaacagg ctggttccaa gtcaatggta actggtacta
    48001 tgcctatgat tcaggtgctt tagctgttaa taccacagta ggtggttact acttaaacta
    48061 taatggtgaa tgggttaagt aatgaaggct aattgtaaac tgtgatggat acttaacttt
    48121 gtataatagg tggataaaag tcttcacaat caaaaaacgc atagtatcaa ggtttttctg
    48181 tactgccccc caaaagttag acaaataatt tatccaaagg atttagttct gtactgcaca
    48241 ggactaagtc cttttagttt taccttaatt ctcttgttgt tgtaataatc aatatagtct
    48301 ataatagctt gttccaattg attaagtgat ttaaatgttt tctcatagcc ataaaacatt
    48361 tccgatttca gaatcccaaa gaaggactcc accatagtgc ttctctgtga atgcctgttc
    48421 caacattgtt tgtacttgtt ctaagttggg tgaagttgaa agattatagg cgataatttc
    48481 actgttaaag ccatctaaaa ctggtgataa gtaaagcttt tgagtacttg ctggaatggc
    48541 aaattctgtc acatctgtgt agcacttttc cattgtttta gagccttcaa attggccttg
    48601 aatgagattc tctgccttct taccaacgtc tcctttattt tcgtttctgt cgcattttag
    48661 cttgtaaatt gagtactttc atcaagcctt gaactctttt atgatttacc agataaccac
    48721 gatttcttag ttctaaatga acccggcgat aagtataatt tcccttgtgt tcgataaaaa
    48781 tggattgaat ttcagcttta agctcttggt ccttatctgg ttt
//
LOCUS       DAVKEV010000010        48465 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVKEV010000010 DAVKEV010000000
VERSION     DAVKEV010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48465
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.010"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..122)
                     /locus_tag="VWZ68_000563"
     CDS             complement(<1..122)
                     /locus_tag="VWZ68_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEU9371638.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERV"
     gene            complement(180..392)
                     /locus_tag="VWZ68_000564"
     CDS             complement(180..392)
                     /locus_tag="VWZ68_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371639.1"
                     /translation="MDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELI
                     KMRFNSSAIDPIYGKKDDASILVIDV"
     gene            complement(735..1031)
                     /locus_tag="VWZ68_000565"
     CDS             complement(735..1031)
                     /locus_tag="VWZ68_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371640.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(1015..3174)
                     /gene="pfbA"
                     /locus_tag="VWZ68_000566"
     CDS             complement(1015..3174)
                     /gene="pfbA"
                     /locus_tag="VWZ68_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEU9371641.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYSGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVVN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKINNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(4304..5530)
                     /locus_tag="VWZ68_000567"
     CDS             complement(4304..5530)
                     /locus_tag="VWZ68_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEU9371642.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFKNEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(5573..6265)
                     /locus_tag="VWZ68_000568"
     CDS             complement(5573..6265)
                     /locus_tag="VWZ68_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU9371643.1"
                     /translation="MLKWEDLPVEMKSSEVESYYHLVSKRKGSLIFKRCLDWFLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(6438..8189)
                     /locus_tag="VWZ68_000569"
     CDS             complement(6438..8189)
                     /locus_tag="VWZ68_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9371644.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDDQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMADTL"
     gene            complement(8179..9924)
                     /locus_tag="VWZ68_000570"
     CDS             complement(8179..9924)
                     /locus_tag="VWZ68_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9371645.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLVFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGTHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(10052..10582)
                     /locus_tag="VWZ68_000571"
     CDS             complement(10052..10582)
                     /locus_tag="VWZ68_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEU9371646.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     PEACRSVGLSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDG
                     VIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYEKEKPGVLYSS
                     KISSNRVNVALPYVGY"
     gene            complement(10579..11035)
                     /locus_tag="VWZ68_000572"
                     /pseudo
     CDS             complement(10579..11035)
                     /locus_tag="VWZ68_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            11169..11996
                     /gene="xth"
                     /locus_tag="VWZ68_000573"
     CDS             11169..11996
                     /gene="xth"
                     /locus_tag="VWZ68_000573"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEU9371647.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            12008..12106
                     /locus_tag="VWZ68_000574"
     CDS             12008..12106
                     /locus_tag="VWZ68_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU9371648.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEY"
     gene            12151..12390
                     /locus_tag="VWZ68_000575"
     CDS             12151..12390
                     /locus_tag="VWZ68_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU9371649.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12773..12868
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            13268..13849
                     /locus_tag="VWZ68_000576"
     CDS             13268..13849
                     /locus_tag="VWZ68_000576"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEU9371650.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13849..15111
                     /locus_tag="VWZ68_000577"
     CDS             13849..15111
                     /locus_tag="VWZ68_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEU9371651.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(15161..15622)
                     /locus_tag="VWZ68_000578"
     CDS             complement(15161..15622)
                     /locus_tag="VWZ68_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEU9371652.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(15619..16383)
                     /locus_tag="VWZ68_000579"
     CDS             complement(15619..16383)
                     /locus_tag="VWZ68_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEU9371653.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYYPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(16564..16968)
                     /locus_tag="VWZ68_000580"
     CDS             complement(16564..16968)
                     /locus_tag="VWZ68_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEU9371654.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVIGQRSEERRVRI"
     gene            complement(17038..18519)
                     /locus_tag="VWZ68_000581"
     CDS             complement(17038..18519)
                     /locus_tag="VWZ68_000581"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU9371655.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWETYVHYPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIVAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVDQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKAFRFAGFEQVKAGIVKWPMSVLRLTSDSKEDLINLADKILQEWRQYSDPAVQ
                     ILAETDRTPHHTITPIARKRDGQFELDLVLRDNQTSAEYPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(18538..19716)
                     /locus_tag="VWZ68_000582"
     CDS             complement(18538..19716)
                     /locus_tag="VWZ68_000582"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEU9371656.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKETVGKHYEEVVGYAPSFYIAEVAGGTHVLD
                     "
     gene            19881..20888
                     /gene="galR"
                     /locus_tag="VWZ68_000583"
     CDS             19881..20888
                     /gene="galR"
                     /locus_tag="VWZ68_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEU9371657.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(20934..21971)
                     /locus_tag="VWZ68_000584"
     CDS             complement(20934..21971)
                     /locus_tag="VWZ68_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU9371658.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(21972..22325)
                     /locus_tag="VWZ68_000585"
     CDS             complement(21972..22325)
                     /locus_tag="VWZ68_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU9371659.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(22569..23459)
                     /locus_tag="VWZ68_000586"
     CDS             complement(22569..23459)
                     /locus_tag="VWZ68_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEU9371660.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            23592..24128
                     /locus_tag="VWZ68_000587"
     CDS             23592..24128
                     /locus_tag="VWZ68_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU9371661.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(24295..25101)
                     /locus_tag="VWZ68_000588"
     CDS             complement(24295..25101)
                     /locus_tag="VWZ68_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEU9371662.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYFSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(25446..26966)
                     /locus_tag="VWZ68_000589"
     CDS             complement(25446..26966)
                     /locus_tag="VWZ68_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEU9371663.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGKTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATIEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(26959..27687)
                     /locus_tag="VWZ68_000590"
     CDS             complement(26959..27687)
                     /locus_tag="VWZ68_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9371664.1"
                     /translation="MIEYKNVALCYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(27701..28465)
                     /locus_tag="VWZ68_000591"
     CDS             complement(27701..28465)
                     /locus_tag="VWZ68_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEU9371665.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGATYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLKNGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(28469..28912)
                     /locus_tag="VWZ68_000592"
     CDS             complement(28469..28912)
                     /locus_tag="VWZ68_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9371666.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(29594..29890)
                     /locus_tag="VWZ68_000593"
     CDS             complement(29594..29890)
                     /locus_tag="VWZ68_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU9371667.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(29912..30976)
                     /gene="pepA"
                     /locus_tag="VWZ68_000594"
     CDS             complement(29912..30976)
                     /gene="pepA"
                     /locus_tag="VWZ68_000594"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEU9371668.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALLGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            31377..32078
                     /gene="galE"
                     /locus_tag="VWZ68_000595"
     CDS             31377..32078
                     /gene="galE"
                     /locus_tag="VWZ68_000595"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU9371669.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMDQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            32501..33460
                     /locus_tag="VWZ68_000596"
     CDS             32501..33460
                     /locus_tag="VWZ68_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9371670.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFISSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            33450..34406
                     /locus_tag="VWZ68_000597"
     CDS             33450..34406
                     /locus_tag="VWZ68_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEU9371671.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            34403..35155
                     /locus_tag="VWZ68_000598"
     CDS             34403..35155
                     /locus_tag="VWZ68_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9371672.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            35251..36216
                     /locus_tag="VWZ68_000599"
     CDS             35251..36216
                     /locus_tag="VWZ68_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9371673.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETSTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(36441..36683)
                     /gene="yidD"
                     /locus_tag="VWZ68_000600"
     CDS             complement(36441..36683)
                     /gene="yidD"
                     /locus_tag="VWZ68_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEU9371674.1"
                     /translation="MKRILIALVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(36683..37405)
                     /locus_tag="VWZ68_000601"
     CDS             complement(36683..37405)
                     /locus_tag="VWZ68_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU9371675.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(37392..37961)
                     /locus_tag="VWZ68_000602"
     CDS             complement(37392..37961)
                     /locus_tag="VWZ68_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEU9371676.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQALDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(37980..38708)
                     /locus_tag="VWZ68_000603"
     CDS             complement(37980..38708)
                     /locus_tag="VWZ68_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEU9371677.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(38708..39448)
                     /gene="xerD"
                     /locus_tag="VWZ68_000604"
     CDS             complement(38708..39448)
                     /gene="xerD"
                     /locus_tag="VWZ68_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEU9371678.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQRRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(39439..39900)
                     /locus_tag="VWZ68_000605"
     CDS             complement(39439..39900)
                     /locus_tag="VWZ68_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU9371679.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(39897..40418)
                     /locus_tag="VWZ68_000606"
     CDS             complement(39897..40418)
                     /locus_tag="VWZ68_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU9371680.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(40394..41365)
                     /locus_tag="VWZ68_000607"
     CDS             complement(40394..41365)
                     /locus_tag="VWZ68_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEU9371681.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(41362..42156)
                     /gene="racE"
                     /locus_tag="VWZ68_000608"
     CDS             complement(41362..42156)
                     /gene="racE"
                     /locus_tag="VWZ68_000608"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEU9371682.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(42363..42611)
                     /locus_tag="VWZ68_000609"
     CDS             complement(42363..42611)
                     /locus_tag="VWZ68_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEU9371683.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(42867..44492)
                     /gene="treC"
                     /locus_tag="VWZ68_000610"
     CDS             complement(42867..44492)
                     /gene="treC"
                     /locus_tag="VWZ68_000610"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEU9371684.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGIKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQTLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(44670..46637)
                     /gene="treP"
                     /locus_tag="VWZ68_000611"
     CDS             complement(44670..46637)
                     /gene="treP"
                     /locus_tag="VWZ68_000611"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEU9371685.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFVYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            46822..47532
                     /gene="treR"
                     /locus_tag="VWZ68_000612"
     CDS             46822..47532
                     /gene="treR"
                     /locus_tag="VWZ68_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEU9371686.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            47687..48375
                     /locus_tag="VWZ68_000613"
                     /pseudo
     CDS             47687..48375
                     /locus_tag="VWZ68_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        14229 a        10960 c         9013 g        14263 t
ORIGIN      
        1 actcgttctt catttgataa atattcaaat aacttctcat atttatcaag cacagatacc
       61 caaatggtct ctaaattatt tgataattct ataatttcat tttctaaata taaccttaac
      121 atttaggtac ctcttcttaa caaagttcaa tagtaacaat taatatttta aacaatatat
      181 caaacatcaa tgactagaat acttgcatca tccttctttc catagattgg atcaatagca
      241 gaagaattaa atctcatctt aattaactct tcaaaagttt tattttgatt attttgatag
      301 aattcataaa agccatcgct cattaaaaca atttgttcac tagtaacatc tatttgatta
      361 ataatagcat ggtctaaaaa tctctcatcc aacgaaccta tccagtaccc actcggttga
      421 ttagataatt ttctgatttt ttgtaaaata atttttttat ttaaaacact atttgtacca
      481 attgaatctt ttatctcatt tttccctttt tcaaataagt tatctactct atgatcagtt
      541 atttccattt cgtttactaa catgacgcag tcacctagca tcatatactc caactttttt
      601 tctgaaagtt tagcaaatat aaaagcaaat attggtaagc gataatatag tatattgaaa
      661 ctagaatagt acacctctac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatt
      721 gatttgtcct attattattt cattttacta tactctgtta attcatatga gtttaaaccg
      781 atttcatctt taacctcgag taaagcagtt tcaaatattt gtttaagagt ttttgattct
      841 ttacaattaa ccgacaaact ttctgataaa atatgtacaa cttctgagac tgaataacct
      901 atctcctctt tagaattata taaatctgta gctccaccaa taatccaaaa atactgattt
      961 tgtgaaccta caatatcctc attttctacg gaacttcctt gtatcgaaca aattttattt
     1021 atctttacca taatacttca acccttttag tgtcaaaagt aaaccaattc ctgtcactgt
     1081 taagaatagt tccataatct tgttcgaacc agtctttggt aatttttgtt ttacatctac
     1141 tatttcttta gatttattaa tatgattttc agtttctctg ccatctccaa ctattttata
     1201 gtttacttct tctgtcttat tatcttgttt attgttgatc ttgtcattca tttgtctatt
     1261 atctttactt gagttaaact ctccgttctt ctggttacta tcaattacat tatttgaatt
     1321 agattgtttt tcctctttgt ttttttcttt ttcgttttta tcacttaaat tatttgttac
     1381 aattttgtaa agcccattct ccgttacaat attgaaatta ccatcgctat cacgtataac
     1441 aggttctttc ccatttgcat tagatttgat gaatgatata tacttaccgg ataaattata
     1501 aaattggtta tttaaaacgg ttattttacc ctttgaatcc tcaataacaa ttccttcttt
     1561 accaccgaat atactattct ctgagactac taaattatca ctaactcgta ataattcaat
     1621 atttggttgt tctgtttcct tagaattatt attaactaca ttttttgtta cagtaatatc
     1681 tgatactttt cctaaatatt ctgcactatc ttttgcaact cgtatcgctt ttgttttagg
     1741 atcggcaata ttaaatatat tttcggcgat aaccacctgt ttatttaaat ctaataggtc
     1801 tttagtgttt ttatagctat aagcatttac taaagctgct ccgctttctc gataatgtac
     1861 actctctcct ttaactttct tatcaaagcg atttcctttg attaatacat cagtgaatcc
     1921 tgtaaaacgt acacctgaat acatcatgtt atcaaaatga ttatttaaaa ttttaatatt
     1981 agaggggttc tgtgtcgaca atgtttgata gtgtgtgcca attgctgtta ctaattcccc
     2041 agatttatca cttttgccaa aataggaatt ttgaatagtc acattttcag attttttccc
     2101 atcatcattc aaggcataag gaaaaccttt tctagttaat ggttcaatct gaatgctctc
     2161 cttacttatg atttgcccat ccttcatcgt tttgggtaag gcttgcccaa gaaaacgaga
     2221 attatcaact aatacatttt tcgaacctgc aatttgaata gcatgccctt gataactatc
     2281 cttgaatgtt acatttttta tagttacgtt atttgaattc ccaatagcaa atgcacctga
     2341 agaatttata agtggtagat tttttgcttt agttccttct tcattcaaag caccgttcat
     2401 atcaatcgta ccaccagaat aactaatatc ttctgttggg ccccattcta cttgcgcacc
     2461 atcatccgta aataaacctg tcataaaaac aatggaaggg tgattcttaa tatttatacc
     2521 atttagaatt gtagctttct cattcaattc taagtgtgta tgacttttta aaaaaacaat
     2581 ttcttttact aaataagttc cttcaggaaa atatacattt cctccaccta gcccttgagc
     2641 tgcagcatct attgcatctt gaattgcttg tcgatcatca tgaatcccat cacctaccgc
     2701 accataatct tttacactta aagcagtatc ttcaaattct tttttgataa ttctgtcact
     2761 tataacatct tccttataac tcttattttc attagtagat gttactgtag attcaactgt
     2821 tctgttgtct aattgtgaat tggaacgaat agtaccatta gagctgatac tattaacact
     2881 taacgaatta tctaaaccat tagtggttga attagaggca atcatttcag cagaacgatt
     2941 ctgattaaca gttggtgaat tatctaaatc attagtaatt gcattagaag actcttttgt
     3001 agccatcggt gaagaactag taacaacttc atccgataaa ataccttggc ttcccaaaat
     3061 tgaaattgcc aatagtaccg agcaagtccc tacctttaat ttacgaatac tgaatacctc
     3121 attaggaaca aaatatttca tcagaacctc caattttttt actattttta acaattgatt
     3181 attacttttc ttaaaataga tagaatgaca ccgctgtcat tatctttatc atatattttc
     3241 caaattgaat tgtcaaggaa taacacaaga aaatattaaa atttatactc ttcggaaatc
     3301 tcttcaaact aggtcagtgc cgccttgccc taagtctagg ttactgactt ggtcagttct
     3361 atagtagacg gaaactataa tagtacacct ctacttctaa aacattgtta gaaatcgatt
     3421 tgactgtccc gatcgatttg tcctattctt atttcatttt actatatcta caacctcaaa
     3481 gcagggtttt gagctatcta tggccaactt cctagtttgc tctttagcct tccattcaaa
     3541 agtgatgcta tctttcttag cttgaatata aaatatccca tttactatat ttaaatttgt
     3601 tgatatgttg taaattataa atgaaagaac aaataccttg tcatacaagc attcgccagg
     3661 gatatttaca tgaatatcgc tcatatggcg gattgaaact aaaacactac aatatatttc
     3721 ttaaatagac cttctataaa agctagattt aacctcgata aaaatagatg cagtgcttct
     3781 aaaatactgg aatagggcat ataggtaatc gtagacaagt gttttataga ttgtctcgcg
     3841 ggagatctaa tgatgtatag caagcatcac taaacatata gaatatttgt attattataa
     3901 gatcaatatg ctataaattc tatcatgcaa aagaatgact agaacatgaa agacaggcac
     3961 aaaactttga acaatattct gaaaacaaaa aaagacgcga gtttccacaa tctcactcat
     4021 ggaaactcac gtctttcaaa aaatagggtg aattgaaaac tagaacaaga cactagattt
     4081 tctaaatgat gtctagtaag gattctaaat gctacaccaa attgctcaca tcttatttca
     4141 aaccacggga ctctcacaag aaaggaaaat cctataaaaa ttctctctct gaggagaaag
     4201 aggcctcaac tacaggtgta aactattatc aattgaaaac aacagttttt acactcaatt
     4261 agacttttta gggacaggat cactttcgct tgactgtagt ttgtcatttt tttgataaag
     4321 ttagcacttt ttcagaaact gttttgaaag tctcaatgat atagtctact tcttcatcgc
     4381 ttaatttagt atgaagaggg agggtaattt cattcttaaa gaaggcatag gccttaggat
     4441 agttcgtcat atcaaatcca agattcttat aggctgtcaa gagaggaagc ggtttgtagt
     4501 gaacattact tgcaattcct gctttagcca attcttggat gatgaggttg cgttcttcta
     4561 ggcttgctcc ttctacacgg gtgatgtaga ggtggcgtga agattcgaca gtttcagtct
     4621 tgtgtgccaa aggatggatg cgagaacctg caaaaccact atcatagcgg tccacaatgt
     4681 ccttacggcg ttgcaacaaa cttggatagc ggtccaattg taccaaacca agtgaagcca
     4741 tgatatcggt catgttgcac ttataggctg gtgtaacgat atcgtattcc catgacccca
     4801 gttgcatctt ggcaagagca tccttagttt gcccgtgaag ggaaaggatt tggaattcct
     4861 tgtacatctc ttcgtcatca atcactggat tggctttcca agtcgcactt ccaccttctg
     4921 ccgttgtaaa gttcttaacg gcatggaatg agaaggaagt aaagtcagcg atagaaccag
     4981 aaggttgtcc tttataagta gatcccaaag cgtgggcact atcagagaca atgacaatac
     5041 ggttaaaggc cttttgccac ttgcttgaag cagtaaagaa gtcacgtttt ttctccacga
     5101 cttggaacaa acggtcataa tcgcaaacaa tccctgcgag ctctactggg ataatcacct
     5161 tagttttctc agtgatagct tgctcaagca ggtcatagtc catctcaaac gtatctgctt
     5221 ggatatccac catgacaggg gttgctccca cgtgcgtaat gacactacat gaagctgtat
     5281 aggtcatggc tggaacgatg acttcatcac caggtcccac ttccaaaacg cgtaaaatca
     5341 actccagagc ggctgtcgca gagttgagac aaacagtctt aggtgtctgt gtgtaaagag
     5401 acaagcggcg ctccagttct tttgttttag gacctgttgt gatccaacca gaacgcaggg
     5461 tatccgctac ttcagcaatt tctgcttctg tgatatcagg cggtgaaaat ggaatattgt
     5521 aatttggcat tgatttgctc cttttatctg tactcatttt cttatgacta ctttatttta
     5581 gtacctcaaa cacggtttga aacatgattt tgatgtcccc aaagaaacta aactctcgga
     5641 gataggcgag gttatagcgc atcttttcag gaagaacatg ctccacatag gcctgatcaa
     5701 ctgacagacc tttctccgtc atttgactga tgatggtgtc ctcatccttg tagttgatgc
     5761 tggctggaga ggtaattcct gcttgcaaga gcaaggttgc catcatttca gggctatact
     5821 gctctgtata acgtggcact tcaggtcgtg taccgacaaa ggacatctca cctttaagga
     5881 cattgaccaa ctgaggcagt tcgtccaaac ggacacgtcg gatgaaattt ccaaccttgg
     5941 taatacggct atcgttagca gaagtcacca gacttccttt tttatccgca tccgtcacca
     6001 tggtacggaa cttccaaatc ttgaaccgac ggttgtactg ggtcacacgc tcttgcttgt
     6061 aaatcactgg ccccttgcta tccaacttga tccaaatgct caagatgaga aagatgggag
     6121 aggttagaac cagtaagacc aaggccaaaa accagtccaa gcaacgcttg aaaatcagcg
     6181 aacccttcct tttagagaca agatggtagt aagactcaac ctcgcttgat ttcatttcca
     6241 caggcaagtc ttcccatttc agcatactgt tctcctttgt ttttattata ctatttgtca
     6301 acatttttca ttataccaca aaatggaaaa ggcggtgaaa gaaatctgta atttgaagga
     6361 tttccttcta gtactcaatg aaaatcaaag tacagctttg agattgcaga taaagctgac
     6421 atggtttaaa gagattttca aagagtatcg gccatggccc ctgcctgcaa actatacatc
     6481 ttgtgatagg ttcctcccag agtcaagagt tcctcatggg ttccactctc gataatgcgt
     6541 cccttatcca agacatagat gcagttggcg tcttgaatag tagaaaggcg gtgagcgata
     6601 gcaatagttg ttcggccctg tctcatcttc gccagagaag cttgaaccaa gctttctgtt
     6661 tcagagtcaa tattggctgt cgcttcatcc aaaatcagga ttttaggctg gctggcgact
     6721 gttctagcaa aggcaagaag ctggcgctgc ccagtagaga agctcgaacc acgctcggaa
     6781 acaggggagt cgtacccctg aggaagttct tgaataaagg aatctgcatc cacaaaggct
     6841 gccgcagcct gaacctgatc atcactgatt tcttggtaca tggcgatatt ggacttaata
     6901 gttccatgat agaggaaggg ttcctgcaag accaaaccga tgttttttct cagctcttct
     6961 tgactgaaat ccctgatatc cacatcatcc aagagaactc tccctgactg gaattcataa
     7021 aagcgcatga ggacattgat aatagacgat ttccctgaac ctgtatgacc tacaaaggca
     7081 atggtttcac ccttattaac agagaaagaa atgtcatcca gaatcggatg tttaccgtca
     7141 tatgagaaac acacatgttc aaaacggata ttgccttctt ggactttggc ttgcccattt
     7201 tcttgaagag gttcataggt cctctcgtct atcagggcaa agacacgacc tgcagaaacc
     7261 atagccgttt gcagagttga aaagttttgc gtcacctcaa tcaaggggtc aaaaaggcgg
     7321 ttgatgtact ggataaaggc atacatggtc ccgaccgtta tcccgataga aaaaccacgg
     7381 tagccaaagt aggccatcaa gactgcatag cctagaagtt tcagcaaact catggcaggt
     7441 ctcaaaaaga gggcatccaa ggctacagaa cggttggcgt agaccaagtg ttcttggttg
     7501 atttcatcaa attctgcctg caggcgcttc tcttgattaa aagcctgaat aatcctgatt
     7561 ccctcgatat tctctgccag cttactattg atatctgaca agagacttct ggttttctca
     7621 atgattttca ctgatttttt ccgatagaga ttgaccaaaa ggaaaatcaa ggggagaaag
     7681 agcaagacta atgctgtcaa acgaaaatcc aataccaaca tggtataaag ggttgtcaga
     7741 aagatgaaaa ctgctgagat aaagctggat aaaatccccg aaaacatatc actgatagtc
     7801 tcggtgtcat ttgtcaaacg agagacgata gagcctgctg gcgtcttgtc aaagtaagac
     7861 atgcccagtt tctccatatt ggcaaaggca tcccgacgaa tatccctaac aatactgtaa
     7921 gacacgcgcg caaagagaag attgcctaca tactgaacta cagtttgtag gatgtagaga
     7981 ccatagtaga ccagcaaaac ggtaacggct agttggttaa gattgctgag atactggtcg
     8041 ataaagtggg aagccacgag gggtatgaca cttttaatga ccgtcgtcgc taggagaaaa
     8101 ctgagtgcca aaaaggtcag gagtctataa ggcttgagat aagacatcaa gcgcttcaat
     8161 acagcccatt gttcttgttt attctgcatc ttcttctcct ttcatttcta actgctgaga
     8221 ctggtaggtt tgggcatacc agccatccat cgctagcaag tcttcgtgcg tgcctcgttc
     8281 gataatttga ccattttgta gaactaaaat aaaatctgca tggacaacag cactgaggcg
     8341 atgggcagtg ataatggttg tcttgtcctt tcgcgtctcc ttgaggttgt cgataatcgc
     8401 atactctgtc ttggcatcta cggcggataa ggaatcatcc aaaatcaaga tatcagggtc
     8461 taaaatcata gcccgactca tagccaaccg ttgcttttga ccaccagaaa gactgactcc
     8521 tttttcacca atcagcgtat caaatccttg aggcatgtct acaatatctt ggtaaactcg
     8581 ggctagctta gtagcttcct cgaccgctga aaggggcaag ttaggattgc caaagcggat
     8641 attgtctagg attgaagttg caaagagaaa ctggtcctga ggaacatagc ccatgagact
     8701 gcgaaggtct gtcagacgat agtcccgaat atcgtgaccg tttagataaa tggcaccctt
     8761 atccacatcg tattcacgca agaggagctt gattaaggac gttttcccag agcctgtctg
     8821 cccaaccaag cccagtgttt gcccttttgc caaactaaag tgaatatccg tcagtgtttc
     8881 ctcattttca aaagcaaagc tgtcaatggc atactccaaa cgcccatttt caataccatc
     8941 cagaggaaac tcagggtctt gtacaggaga ttcctgagac aaaagatttt caatccgctg
     9001 gtaagaaacc ttccctcgct gagtagtatt aaagaggaag ccgatggcca taagaggcca
     9061 gaccagcata tccaaatagc tgataaaggt gactagattc ccaactgtaa tctgcccttc
     9121 ctgaaccatc aaggagccaa ccaaaagcgt taaaacatag gacgaaccaa caaacacgag
     9181 aaccataggg tcaaagagac tatcatattt catggtttgc aggttctttt ggaaggttaa
     9241 ttcattgact gcctgaaaag acttcaactc gtctgcctga taaccgaaag acttggtcac
     9301 tttgatacct gatacggact cctgtacctt gttattgagt tcagaaaaag cagcttggga
     9361 ttcgccaaag gccttatgag tctttctccc taggcgacta gtcgcatagg ccatgaaagg
     9421 tagggggaga atggcaacaa gagtcatctg ccatgagatg ctaaagagca tggtcaacaa
     9481 agtcaccaga gccgtgatag aggcatccac cgcagacatg acaccgccac ctgctaaacg
     9541 agtcaaggca ttgatatcat tggttgcgtg tgccatcaga tcacccgtcc gataggtttg
     9601 ataaaaggct gatgacattt ttgtgaaatg cttaaacaag cgagaccgca tgatctgtcc
     9661 caagcaataa gaggtcccaa ggatatacat acgccacaca tagcgcaaat agtacatacc
     9721 aaaggctgca agtagcaagt aaaataggct aagaaggagg tcctgctggg ttaattgccc
     9781 cgatgtgatg gcatcaatga cccgccccat aaccatagga ggaatgagat tgagaacgga
     9841 aaccaagacc agggccacaa tcccgactag ataacggcgt ttttctaact tgaaaaacca
     9901 ccaaagtttt tgaataatgg acataaaatc cctttctgat tgcaaatgga aacctgaggc
     9961 caatactcaa tgaaaatcaa agagcaaact aggaaactag ccgcaggctg ctcaaagcac
    10021 tgctttgagg ttgtagatag aactgacgaa gtcagtaacc tacatacggc aaggcgacgt
    10081 tgacgcggtt tgaagagatt ttcgaagagt acaagacccc aggtttttct ttttcataag
    10141 ttacgactgt aacagcaccc ttgtcatatt cagcaataaa gatattggct acattgtcat
    10201 gcccttgttt actgaggtta tcaagcaacc actcttcgct acgaccaatc gattccaaga
    10261 catctacttg aatcacaccg tcagtcacaa ctggatactt aggattttca tctcccattt
    10321 gcacaacgat aagttgccca ttttgctctt gcacagctcg tttgacttgc ttcatctgga
    10381 aaatcccttg gctacgaagt ttgagggcta catccgatgc agacaaacca actgaacgac
    10441 aggcttctgg gtcaatattc ccatttttga taaggagagt tggcttacca tcaatcaaac
    10501 gtttcacaaa gtgaacattg ttgttgagcc atttgagagt caagaccagt ttgattaaaa
    10561 tttcgatata attaagtgtc atttgttcac atccaccagt tcaattgcgt ctgtcttata
    10621 caattcgact ttctctaaca ggtacttgtc tggctcactt ccgtttaggg cacgataata
    10681 gcgatctccc accttgataa gtgcgccatc tgtgtttgtg gaagtattaa catagacttc
    10741 tgacttgtct actcccaaat ctttggaaac aacctcgatg aaatgaagtg aagtttgaaa
    10801 tttattgtta gaaacttgat tgttttgata agtcgtgatg ctgaccaaaa gcagagctaa
    10861 ataaggccag agctgaaatc atgaccaact cacgaaattc ggttcccttt ttatcatggt
    10921 atgccttgaa agcaaaaaaa actgtcacag ctaatagaac aatcccaaag ccaaccatga
    10981 taccattttg ctgaccgatt tggctgagta catagtcata agagtagaat ttcatatatt
    11041 ttcactccct ttcataaaat cattcttaat tataaacgaa agagagtaat ttttcaaacc
    11101 atacgttggg gaaatagatc tttttttggt ataataaaat ctataatctg aatgaaaaag
    11161 gtaactttat gaaacttatc tcatggaata ttgattccct aaacgctgcc ctaactagtg
    11221 actcagctcg tgccaaattg tcccaagaag tcctacaaac cttggtcgct gaaaatgctg
    11281 atatcattgc tatccaagaa accaagcttt ctgccaaagg acctacaaag aaacacgtgg
    11341 aaattttaga agaactcttc ccaggctacg aaaacacatg gcgctcttcc caagagcctg
    11401 cccgtaaagg ctatgctgga accatgttcc tttataagaa agaacttacg cctacgatca
    11461 gttttccaga aatcggtgcc ccttctacca tggacttgga aggccgtatc atcactctag
    11521 aatttgatgc atttttcgta acccaagttt acactccaaa cgctggtgac ggtctcaaac
    11581 gcttggaaga acgccaagtc tgggatgtta aatatgctga gtatttggct gaactagaca
    11641 aagaaaaacc agtccttgcg accggtgact acaacgtagc ccacaatgaa atcgaccttg
    11701 caaatcctgc tagcaaccgc cgttcacctg gatttactga cgaggaacgt gctggattta
    11761 ccaacctttt ggcaactgga tttacagaca ccttccgcca tgttcatggc gatgttcctg
    11821 aacgctacac ttggtgggca caacgcagca aaacttctaa aatcaacaat acaggctgga
    11881 gaatcgacta ctggctcaca agtaaccgta tcgctgacaa ggtcactaaa tctgatatga
    11941 ttgactcagg tgctcgccaa gaccatacac cgattgtctt ggaaattgac ttgtaaggat
    12001 tttctatatg gactacaatg cggtcattcc cgagtttctt gtatcgaata tcgaacagtc
    12061 ccggtccttc tactgtggtt tactgggttt taggattgaa tactaacgtc cagaagaaaa
    12121 ctttctcttt ctcttgaaga gtgtcaacta atgttagagg agggaacaaa ggatcaacta
    12181 gctgaactga cctacccctt tggtcgtgga gtcaatctct cctttggcat aaaggatgtt
    12241 ccaaaactct atcaaaaagt gatggaggca aactatccta tttatcgtct cttgaccaaa
    12301 agaaagtttc gtgtcagtga tccctatatc tatcctcata aatttgcagt tttggatcca
    12361 gatggctatt ttttaagatt tagcgagtag aataataaaa attgggaaaa gtctttaaag
    12421 ttagaaaaag gcatattgtc aggtgtctaa aaacttgata gtatgccttt tatgatggaa
    12481 aaatcttcta atactcttcg aaaatctctt caagccacgt caacgtcgcc ttaccgtagg
    12541 tatatgatac tgactctgtc aattctatcc acaacctcaa aacagtgttt tgaggttgtg
    12601 gatagcttcc tagtttgctc tttgattttc atttagtata aatgttagct tacaatgaag
    12661 tttttgttca ccctctcttc tttttgttcg ctttttaaac caaaacacta acaaaatagt
    12721 tgatttctaa agttatttag tgtaaaataa aaacattggc tcaagcctat ttaaaattga
    12781 atatcgtttt acttgtttat gtcgtgaatt ggcacgacgt ttctacaagg tgccggaaca
    12841 cctaacaata agtaagtcag cagtgagata tggccgtttt tgccatgtct atttagggga
    12901 cttacttaga gattaagtag gtcttttttg aatattttta atatttccct taattagtgc
    12961 ggacgggagg tgaaattatc ctgtgaataa tttcaggaat ccagggaatt tcatccctaa
    13021 tttttgagcc cctagctctt tcatttctag gcttaggcta aaatagttcc ccgaactatt
    13081 ttactctcaa aaatcccgtc atagacaata acaagattat tgtctatgat accactacaa
    13141 cgggaaatat ttgataagac tcgcttcgct cgtaatagtt ttatcaaata tatagtatta
    13201 gcaaaaggga tcactataga aatatttaaa caacaagtaa attaactttt agactttagg
    13261 aggtcttatg aaattattag aagagcgcat cctcaaggat gggcatatct tgggtgataa
    13321 catcctcaag gtagattcct ttttaaccca ccaagttgac tttagcttga tgcgagagat
    13381 tggtaaggtt tttgcggaaa aatttgctgc tactggcatt accaaggtcg taaccattga
    13441 agcgtcgggt attgccccag ccgtttttac agctgaagcc ttaaacgttc ccatgatttt
    13501 cgccaaaaaa gctaagaaca tcaccatgaa cgaaggcatc ttaactgctc aagtctactc
    13561 ctttaccaag caggtgacca gcactgtttc tatcgctgga aaattcctct caccagagga
    13621 caaggttttg attatcgacg atttccttgc taatggccaa gctgctaaag gcttgattca
    13681 aatcatcgaa caggccggtg ccacagtcca agctatcggt atcgtgattg agaaatcctt
    13741 ccaagatggc cgtgatttgc ttgaaaaagc aggctaccct gtcctatcac ttgctcgctt
    13801 ggatcgtttt gaaaatggtc aggtcgtatt taaggaggca gatctctaat gcaaactcaa
    13861 gaaaaacact cgcaagcagc cgttctgggc ttgcagcact tactagccat gtactcagga
    13921 tctatcctgg ttcccatcat gattgcgaca gcccttggct attcagctga gcagttgacc
    13981 tacctgattt ctacagatat cttcatgtgt ggggtggcaa ccttcctcca actccaactc
    14041 aacaaatact ttgggattgg actcccagtc gttcttggag ttgcattcca gtcggtcgct
    14101 cccttgatta tgattgggca aagccatggt agtggcgcta tgtttggtgc ccttatcgca
    14161 tctgggattt acgtggttct tgtttcaggc atcttctcaa aagtagccaa tctcttccca
    14221 tctatcgtaa caggatctgt tattaccacg attggtttaa ccttgatccc tgtcgctatt
    14281 ggaaatatgg gaaataacgt tccagagcca actggtcaaa gtctcttgct tgcagctatt
    14341 actgttctga ttatcctctt gatcaacatc tttaccaaag gatttatcaa gtctatctct
    14401 attttgattg gtctggttgt tggaactgcc attgctgcta ctatgggctt ggtggacttc
    14461 tctcctgttg cggtagctcc acttgtccat gtcccaactc cactctactt tgggatgcca
    14521 acctttgaaa tctcatctat tgtcatgatg tgtatcatcg caacggtgtc tatggttgag
    14581 tcaactggtg tttatctagc cttgtctgat atcacaaaag atccaatcga cagcacgcgc
    14641 cttcgcaacg gttaccgcgc agaaggtttg gccgtacttc tcggaggaat ctttaacacc
    14701 ttcccttaca ccggattttc acaaaacgtt ggtttggtta aattgtcagg catcaaaaaa
    14761 cgcctgccaa tctactacgc agctggtttc ctggttctcc ttggactgct tcctaagttt
    14821 ggcgcccttg cccaaatcat tccaagctcc gtcctcggtg gtgccatgct ggtaatgttt
    14881 ggttttgtat caattcaagg gatgcaaatc ctcgcccgtg ttgactttgc taacaatgaa
    14941 cacaacttcc ttatcgcagc tgtttcaatc gctgcaggtg tcggtctcaa caacagtaat
    15001 ctctttgtca gcatgccgac agccttccaa atgttcttct caaacggaat cgtcgtagcc
    15061 agcctactcg ctattgtcct caatgccgta ttaaatcata aaaagaaata agaaaaagag
    15121 gtgcgagcct cttttttgtt gacaaaataa aaacatctac ctattcatat atgctagtgt
    15181 catagtcctg aaaatcatct gcatcaagaa caatttcaca actcttatac ttttctctta
    15241 caagtcgttc ggcttcatct ggattttcag cctctatact tactaaacgt gataaagttt
    15301 ctgtaatttc tactgtatac tttttcagtt ttagattgct ttccaataat tcacctatta
    15361 acaataatct atgataggag ctatgtagcc actctggcaa tttatctcct acttcccacc
    15421 catatttttc cttcatcaaa gctagttgtt tttcgtcacc aaatttcata ttttcagata
    15481 accatctcac acaatcggga tctgataagg tacagacgat taaacttagg ttatcgtaac
    15541 ggctttcagt ttcataatca ggccagatga cttttaagaa atcatacacc tcttctgatg
    15601 caacaagttg tttcgttttc ataatttccg atactttcct ctacctttaa attctattat
    15661 ttctttgtct cttaatattt gaagctgttg cctaatcttt tctttgatat gattgttctt
    15721 aacaaagata ttttttaggt cactttcaaa acgatacata tcttcaaggg taaattctga
    15781 accctctatc ttatctatac aatttagaat ttctattgtc caacctcttg atgacagaga
    15841 gctcttcctt aaaaataaac cttgcttaaa ttcttttgta actttttctg gatctctaac
    15901 ttgtccatct tgcacaagaa atatccttcc tttagaaggt acttgtgata aatcaatgtt
    15961 acaaccaatc caacctgctc gtctagcagt tggtgcaagt ggttttcttt gaataatcga
    16021 tttcggtgta acaaattgct tcggaaggac aagaaagtta tttacctcaa aattttttgt
    16081 gtaagttaaa aaaaagaaat taggattatt atctgcctgc acacgcttca tcatcgttgc
    16141 ataagcacca tcattgattg ttgatgaaaa atttcctttt ttgctcttta gttcaaactc
    16201 ctcactacaa tgattacagt aaaaatctgc tacaggccga ttattttcaa aatgatttaa
    16261 gggattgttc ccacaattag ggtaataaga ctgacgataa acccaatcct ccgttaagat
    16321 acgtgccttt tggctattac ttttataggt ttctactaat tctaaattaa agtgtaattc
    16381 catttaaaaa ttcctcacta atatgagaac tcactcgata taagcaatta aaatctacta
    16441 taactagtat accacatata tgtacctatt acatttgtat ttcatcactc tcttttatat
    16501 ttccttctaa catatctcat aaattaaaaa tgagtgagat aaatttatcc cactcacctt
    16561 tctttatatc cttacccgtc tttcctcaga cctttggcct atgacaaaca tggtaaaggt
    16621 tgctttgcag acatttctgc cctcttgatt ggtgatatcc acatccatca cacaggttgt
    16681 acggccttga tggacacatt ctcctttaat ggtcaataca tcgtcgagtt ttcctgcctt
    16741 aaggtagttg atagaggatt ggagtgtcac cccatcaagt cccagcgaga taaccaccaa
    16801 accactgatt tggtcacata gcgtgaatag atagccacca tgggcattgc catagtagtt
    16861 gagcgacgag ttcactactt tggtcgtcac cacaacgtga ccatctctca ttttttcaat
    16921 ttcgtaattt tcaaaggcag atatagcgtc aaaatgaaag tctttcatcg tttcctcctg
    16981 atatttcaaa cgacactatg atactacttt ttataggact gtgcaaggag aaagctccta
    17041 gtctagtaaa attccgacat gttccacaaa gcgcataaag gctgtctgcc cttgttctgt
    17101 ctgcttgtag actcctgcat cctcaagtac acgcgcaaag atagcaccca cagagtcctt
    17161 gacgattgca agggcttttt ctttatccgt taggtctgga tgttgggatt tgagttggtc
    17221 tgcccactcc tgatgataat cggcaactgt aacagcttct cctacaagat agctcgcgac
    17281 ttgctccact tcttctttca gacgtggtgg caagattgcc aagcccatga cctcaatcaa
    17341 gccgatattt tccttcttga tatgttggac atccttgtgg ggatgataga taccatcagg
    17401 atactctgct gaagtctgat tgtctcgcaa gaccaagtcc aactcaaact gtccatcgcg
    17461 tttgcgggca atgggtgtga tagtgtgatg cggtgtcctg tctgtctctg ccaaaatctg
    17521 cactgcagga tctgaatact ggcgccattc ctgcaaaatc ttatcagcca aattgatcaa
    17581 atcctctttg gaatccgaag tcaaacgtag gacagacatg ggccacttga caattccagc
    17641 cttgacctgc tcaaaaccag caaatcggaa ggccttttgc aagggagcca attccatagg
    17701 aaatacgtga cggcctccct gataatgatc atgagttaga atagagcccc ccacaatcgg
    17761 caggtcggca ttagatccag caaaatatcc tggaaactgg tctacgatag ccaacagacg
    17821 ttcaaaactc tgacgactaa tggccatggg acgatgctgg ccatctaaaa agatacaatg
    17881 ctcattaaag taagcatagg gcgaatactg gaaaccccat tcctgaccaa ccatttcaaa
    17941 acggataata cggtgattgc tacgagctgg gtggttaact cgaccatggt agccctcatt
    18001 ctctagacaa agctgacact gaggataatt actagcttgc accaacttgg ctgccacaat
    18061 ctctttcgga tccttttcag gcttagagag attgatggta atttcaagtt ctccataatc
    18121 agatggaaca cgataagcga tatttttagc aatggccttg agtttgatgt agtcattttt
    18181 ctgactgagt tgataaaaat cctctatcgc ttgctcagga tagtggacat aggtttccca
    18241 gaagtcacga ttgacctgac tcggacaagg agtcaccaag tccatcagtt cagtaccaag
    18301 gatttcacgc gcagtctgac tatcctcaat cgtctctaat cgaacggctt cctcaactag
    18361 ctggtccttg aggtcaatca atttatccag attggtctca acttccaaaa caccttctcc
    18421 cactcgtgcc aaaacacgat tggtcaggta gattcgatcc atttcctcaa atgaactttc
    18481 agaaatgaca tgtgttacaa atttatctac taaggtcacc atagagcctc cttttgacta
    18541 gtcaaggacg tgagtgccac ctgcaacttc agcgatatag aagcttggag cgtatccaac
    18601 tacttcctcg tagtgtttgc ctacagtttc cttaaaggcc tcaacagtat ctttttgaac
    18661 caaggcaatg gcacagccac caaaaccagc ccctgtcata cgagcaccga gaactccttc
    18721 ttgtgcccaa gctgtgtgaa caagagtatc caattccaaa ccagttactt cataatcatg
    18781 ctccagagaa acgtgtgacg cattcatcaa acgaccaaat gtttccaaat cacctgcttg
    18841 aagggctgct tgagctttaa gggtacgttg gttttcaagc acagcatggc gagcacgttt
    18901 caaacgattt tcatctttaa tcaaatagct atattggtca acggcccact cgtccaattc
    18961 acccagggtc tgaatatcca aggcaacttg caattcttcc actgcttttt cacactcagc
    19021 acgacgttca ttgtatttag agtccgccaa ttcacggcgt ttgttggtgt tcatgataac
    19081 aacgacattg tccttcaaat caagtggcac caaatcatac tctaaggtgt tggtatcaag
    19141 gtaaatagca cgttgatcgg cccccatacc aatagcaaac tggtccatga taccagagtt
    19201 gactccgata aagttgtttt ctgtttgttt tccgatttta accaaatcga gacgctctaa
    19261 ttttaaatca aagagatgct ctgccacgac tcctgtcaag agctccaagg atgctgaaga
    19321 agacaagcca gcaccatttg ggatattccc ataaacataa aaatcaaaac ctttgtcaat
    19381 cacgtgccca gcttcttgca agaaatgaag gacacctttt ggataattgg tccagttgtg
    19441 ctctttttca aacttgaggt cagcgagagg cacttcgata atgcccttgt cctcaaagtt
    19501 agctgagtag aaacgcaaga cttggtcgtc acgcttacga gctgcaccgt aagttcccaa
    19561 ggaaatagca gcaggaaaaa cgtgcccacc gttgtagtct gtgtgttcac caatcaaatt
    19621 aatacggcct ggtgaaaaga aggtttggtc tgcttcttga ccaaaaacag caagaaagtc
    19681 tttgcgaagg acttcagtag taagatgttg tgccatatga attctccttt gactgtccgt
    19741 taagccatct taacgtgtaa tcgttttctt tctattgtat ccaaggaatt tcccaaggtc
    19801 aatccttttt actaaaattt tactaaaata tcagtaaaaa gaagaaaaat atgatatact
    19861 aacctaatca aggaggattt atggctacct taaaagacat tgcacagcta gcctctgtct
    19921 caatcgcgac cgtatcccgt gtcctcaacc gcgaccagag cctatctgtt acagaagaaa
    19981 ccagacaccg tattttaacc gttgctgaag agctaggcta caccaaacac ctcaagacag
    20041 gcgagtccca caagcccaag caaaagattg ccattatcca atgggtcagc gaacaagggg
    20101 agctagacga cctctactac taccagattc gcctaggaat agaaaaaaga gcccaagagt
    20161 tggactatga tatcttgcgc tattttaatg accatccttt taccctaagc gaggaagtga
    20221 ttgggattct ctgcatcgga aaatttagcc gagctcagat ttctgccttt gaagaatacc
    20281 aaaagcccct ggtctttcta gacagtgata cactttccct ggggcatact tgtattatta
    20341 cggattttta cactgctatg aaacaggttg tcgattattt cctcagtcaa gggatggacc
    20401 gcatcgggat tctaacaggc cttgaagaaa caacagacca agaagaaatc attcaggaca
    20461 agcgtctaga aaacttcaaa aactatagtc aagcgagggg aatctatcat gatgaactgg
    20521 tctttcaagg aagatttact gcccagtctg gctatgactt aatgaaggag gccattcaga
    20581 gcttgggaga ccaacttccg ccagcatttt tcgcagccag cgatagttta gctatcggtg
    20641 ccctccgtgc cctccaagaa gctggaatca gcctgccaga tcgcgtcagc ctcatttcct
    20701 ttaacgacac tagtctgacc aaacaggtct atcctcccct ctctagtatt acagtttata
    20761 ctgaagaaat gggccgagca ggtatggata ttcttaacaa ggaagtcctc cacggtcgga
    20821 aaatccctag cctgaccatg ctgggaacca gactgacatt aagagaaagt accctaaatc
    20881 aagaatagga taacataaaa aacgaataga gttctaaaac tcctattcgt tttttattcg
    20941 attacaatca tagacttaat tgtcttacgt tcatccatat ctttataggc ttggtcgata
    21001 tcttccagtt tataacttga agtaaagacg cgacctggat tgatatcacc atcaaggacg
    21061 gcttttagta aaaattgctt atcgtatgtt gtagcagaag ctgccccacc tgctacagag
    21121 atattttgca taaatgtcga accaagagca cgattattat agtgtgggac tcctacaaag
    21181 cccatacgcc ctccattatg aagaacacct agcgcctgtt ctatagcagc ctccgtacca
    21241 acacattcaa gtgctgcatc tgctcctcca ccgaggattt cacgcacctt ggtaattcct
    21301 tcttgaccac gttctgcaac aacagctgtc gcacctgact ccatagccat cttttgacgg
    21361 tcttcatgac ggctcataag gataatttgt gatgctccac gcatcttagc cgcgatgaca
    21421 gcacattgac caacagcccc atcaccgata acaacaacct tgtccccttt ttgaacattt
    21481 gcaacacgcg ccgcatgata gcctgtcggc atgacatctg caagagtcaa aagggacttg
    21541 agcatccctt ctgtatagtc agaaggttga ccagggattt taaccagcgc ccagtttgca
    21601 tagtggaagc gaatatattc tgcctgaaaa tcacccccca aattattgcc aatatgattg
    21661 tcgcaagaac cgtcaaatcc agcaagacag gcatcacact caccacatcc atgtgtaaaa
    21721 gggacaatca caaaatcacc tggtttcacc gtcgtaatgg cttccccagc ttcttcaaca
    21781 atcccaatcg cttcgtgtcc actatttttg tgtccagctt tcgtttctgg attacggtac
    21841 ctccataaat ctgaaccaca aacgcacgca cgaaccacac gaataatcac atcatccgct
    21901 tctattattt gcggacgttc aatgctagca agtccaacct gacctgcctt tgtatatact
    21961 gctgatttca tttaaaattt tccttcctta taaagtttaa ttttgagatt taaacgattt
    22021 aaagctgtct gtagctgaga caagcgctcc tctaattttt gcttttcctc ttctaaaata
    22081 ccaagcctct cctctctcgt ttcatctccc ttttggtaga gcgacatata gtcaactaaa
    22141 ctatctacag agacacccgc cgaacgaaaa cacttaataa attccagcgc ttcgatatcc
    22201 tgatcttgaa aatcacgaat cccagtagca gtacgagtaa tcggtggcac aagaccaacc
    22261 cgttcataat accgaatcgt atccgctgaa attcccaaca aatcactggc agatttaata
    22321 ttcacacgct aacctcctct catttcattc actgaattca cgctattcta actcacttat
    22381 cttattatat aactttgagt tgactccaag tcaagcattt tgtatctaat cgaaaaattt
    22441 ttatcattaa caatcatata tctggagttt atacaatgct cttctcttac caatttttga
    22501 aatatttaaa taataaagaa attactctat tccaaataag atagtaccca agtatttttc
    22561 acttttttct aatgttgatg ctcataactc cgttccaagt cacacacctt tcgcttatgg
    22621 gtttggtgag tttctaggtc agcatcaatt tcaatggtaa tattttgaaa accacaatct
    22681 tttaggaaaa ttcgaataga ctctttacaa gtttccatat gttccatttc ttttagacaa
    22741 acatggacaa tggcattttt ttccaaagca tccatagtcc agagattaag ctgattaagg
    22801 ctggccacat tgtccaatcg ctccaggcca ctctttactt gcttgatatc aagaccttct
    22861 ggcacagcat ccaagaaaat cttgagtgta gaccaaaaac gtggaagggc ttttgaaaga
    22921 ataaagaaag aaatgacaag ggacaaaaga ggatctagga tataccagtc cgtaaatcga
    22981 agaacaatcg ccatcaggat aacagctacc caccctagcg tatcttccag aaaatgcaga
    23041 ctcagaatag actcattctt tgtctttccc ttaccaacca ccagactcgc taacagattg
    23101 atagtaatcg caataattcc taaccagaga atcccctcat cattgactgg ttgcggatgc
    23161 aaaatcttcg tgacattttc caaaatgact agaacagagc ccgttacgag aatcacagct
    23221 gttaccaagg ctcctagcag gctaaaccgc ttatagccca aggtgtactg attgtcttct
    23281 tcacgattgg agattgtttc tagaaaagct gatattccaa ttgcaatcgc atctcccaag
    23341 tcatgcacag agtcagcaag aacagcgcta gaaccaaata ctccacctgc aataaactca
    23401 acaatggcat aagtcaaatt taagaaaaaa gccacccaaa cagcatattt tgccttcata
    23461 tttctcattc ctttgttata atagatttat gaacaccttg ttcattatca ttatccacta
    23521 aaactcaaag aaaggataga agcaaaacgt cagctttatt cagttctgaa caatttgcct
    23581 taagtgtcca tatgactaac attgaccgcc gtatcagcaa aaccaaaaaa gccatctatc
    23641 aagcttttat acaacttttg aatgctaagg gctacgaggc cactactgtt caggatatca
    23701 ttgatctcgc agatgtggga cgatccacct tttactgtca ctatgagagt aaggagcttc
    23761 ttctggacca gctctgccgc tacctcttcc atcatctttt tgaaagagag caagccattt
    23821 caaccgagga ctacctcgcc cacctctttc tccattttca taaaaaccaa gaccatatca
    23881 ccagtctgct attttccaaa aatgactact tcctccgtca actccataaa gagctagaac
    23941 accatgtcta ttccgtgcta gctgataatt taaaagaagc ccaccctaat ctgcctactt
    24001 cttacctcca acacttggtc atgtccaact ttatcgagac attgacctgg tggctcaaaa
    24061 aaggtcaaga tttcacagac caggaagttg tccaatttta tctagacctt ctcattccta
    24121 aaaattgaat atagagtaaa gcttcagttg tcttatttct aggttactga gttttttatc
    24181 ttttcaacaa caaaagagga cccgccgatc ctctttttca tactataaat ccttgattat
    24241 caactatatc tgttttaatc gaaatctcaa aacagcactt tcaaacatct tttcctagtt
    24301 aagtaaatca gtattctgct tagctgcctt gctccattga taccaaccaa ctagactgtt
    24361 aatgagataa attagatatt tcccttgaat ttgcaggctt tctccccacc agagatagat
    24421 tgaaaagaca ttggtagccg cccagaatat ccactgttca cggtaaacag ctgtcatgag
    24481 gatttgccct accccattgg ttgcatctgt gattgaatca cgatagggac gattggcacc
    24541 aatagactga taaatgaagc caaaggccaa ccaccaaagc acactaatgg aaaaatactt
    24601 tgtccagccc ttgccgtcca gtttacgcgc gacaaactcc tgcttttcct tcttaaactg
    24661 tgcctgataa atccaaacta gaagtccaat tggctgcatg actgtgaagt aaagtgtcgt
    24721 cagcacctca ccataaaagc ctttctgtag ggccaaaata aggtaaataa cagagttaat
    24781 caagccaaaa agataattac ttgctcgacc ttccgataca aagattacac agataatccc
    24841 tgtcaagcta caaatcatcc caatccagtc aacaatacga tgttcgtaaa ccaactccag
    24901 ccagagagga aaacttccta aaaccagcaa ataaatccac tgggcaaaac tacgatgggc
    24961 aaagaggtca tcccagatag ccttcatagt tcctgaaaat cctaaatcag ccatagccgc
    25021 aaccatacga cggtaaccac ctgacatttc acctagggtt gttttgatat tttcaatttt
    25081 cttttgcaaa taagtatgca tcatttctcc ttttgttttt aaagagccgt gtctggatag
    25141 actttcggac gcaacgctct attagataat gaactgccta tacacaagat ttctaacctt
    25201 agtcgacatg agctgaaacc tcttatttgt taagtagttc acaaaatatt atacacctat
    25261 tttatgaata gtcaactgtc tttacagtaa aattttagaa aatcatgaaa attttctctt
    25321 tctttccatt ttaagtgaca ttcagtcatt ctcacatcaa aaaagcccag acgaaattgt
    25381 ctgagcattc ttttatctag tcgtttaagg aagttgagtt cagtatgttt aaagtctctg
    25441 tcccatcatt tcttcaacaa accttgttct tggagaaact ccttggctac ttgctttgct
    25501 gacttgcctt caacaccgac ttggtagttg agctgactca tctggctttc tgtaatctta
    25561 ccagccaatg tattaagaac tctttccaac tctgggtgtt tcttgagaag agcttctttc
    25621 atgagtggag ccccttgata aggtgggaag agttgcttgt catcttccaa gacctgtaaa
    25681 tcataacgct ccaattccgc atcagtcgaa taggcatccg tgatttgaat atcccctgac
    25741 tgaatagcct gatagcgaag ggctggctca atggtcgcta cattgagatt gagaccatac
    25801 attgattgca agcccttatt tccatcttca cggtcgttaa actcgagtgt aaaacctgcc
    25861 ttcaactgcc cttccacttt tttcaagtct gaaatggtct tcaagccata ttcttgagca
    25921 atctttttcg gaacagctac agcataggtg ttttgataag acatgggttt gagataggct
    25981 agatgatcct gcttagcaat gccatcacgc gccacctgat aaacctgttc tggttcatga
    26041 ctcaccttgg gtgatggttg aagcaaactt tcagtcaccg taccagtaaa ttcaggatag
    26101 atgtcaatat cgcctttttt cagagcttca taaaggaagc ttgtcttccc aaaattcggt
    26161 ttaacagtcg cagtcatgct ggtattttct tcaatcagca acttatacat attggccaaa
    26221 atttctggtt ctggacctat tttcccagca ataaccaagt tttccttctc tttttgaacc
    26281 aaaagagctg gactataaga cagacccagt aataaagcca ccaaggcaaa acctgagaaa
    26341 atcgtccgta attttgcttt ttccatcact tttagtagga agttaaaggc aatggctagc
    26401 actgcagaag aaagtgcccc aatcaaaatc aaactggcat tattacggtc aattcccaaa
    26461 agaataaagg aacctagtcc ccctgcacca atcaaggccg ccaaggttgc cgtaccgata
    26521 atcaaaacag ctgccgtccg aatcccagac atgataacag gcatggcgag tggaatttca
    26581 aatttcttga gacgttccca tctggtcatc ccaaaggcaa tcccagcctc ttgcaggttc
    26641 ggatcaattc ccttcagccc agtgatagta ttttgcaaaa tagggaaaat cgcataaatc
    26701 actagagctg tcaaagccgg caaggtccca attcccatca aagggataaa gagccccaac
    26761 aaggccagag acgggatggt ctggaaaata cctgcaatct gcaagaccca gtcggccagc
    26821 ttctcatgat agcgaagaaa aacagccaag ggaatcgcaa gcaaaatagc tagtaacaag
    26881 gtcaaaagcg acaactgcaa atgttgagat agagctgtca accaatcact aaaacgatcc
    26941 tgaaaagttg caattaaatt agtcatgaac actacctcca aacaagtctg ctacaaagtc
    27001 tgttgcaggc gcttttaaaa ttgtctcggg attcgctacc tggcgaattt ctccatcctg
    27061 caagacagca atacggtccg ccaacttcaa ggcttcatcc gtatcatggg ttacaaaaat
    27121 cgttgtcatc ccaaactctt tatgcaattc ttttgtcaga acctgcaact gttttctcga
    27181 aatagcatcc aaggccgaaa agggttcatc catgaggaaa atcttgggct gaccaatcat
    27241 agctcggaca ataccgaccc gttgctgttc tccaccagat aattcactag gtaagcgatg
    27301 cccatactcg gctactggta aaccaacctt agccaaaagc tcttctgttt tcttcgtaat
    27361 ttcttccttg ctccacccct tcatttcagg aatgagagca atattttccg caactgttag
    27421 atttggaaaa agagcaatag cctgtaaaac ataaccagta gaaagacgaa gttcacgctc
    27481 atcatagtct ttgatgcgct tcccatccat ataaatattt ccatcagttg gttccaaaag
    27541 acggttaatc atcttgagca tggtcgtctt acctgaccca gaaggcccta ctaaaaccat
    27601 aaattcccca tcctcaatct gtaagttgac atctctcaag acatcctttt ctgtgtagca
    27661 tagtgctaca tttttgtatt caatcattct ttgtcctcat ttaaaacttc cctcgattgg
    27721 tcaagtcttc taccttaggc atgacttcct tattatccca atgctccaca attttcccgt
    27781 tctttaaacg gaagatatcg tactgggcat aagcaacgcc atcaatctga gtctgaccat
    27841 agctaaccac atagtttcct tgtcctaaga gttggaaaac aaagtcaaaa gtgacactat
    27901 attcagccac atagttttta taagcagcac ttccttgtcc aatatcatga ttatgctgaa
    27961 tcaaatcgtc tgccacataa tcactccact gctctagctc cccattttgg aaaatttctg
    28021 tcaagaaacg gcgaaccagc tttttatttt ctgctttctt gtccaaatcc ttgatttcaa
    28081 aatctccaaa aatttgatct agttggtcat tttcaggtgt tcgatagtag tcaatgacat
    28141 cccaatgctc aacaatacga ccattctcat ccgcacgaaa agtatccgtc gtcacccatt
    28201 gagcttctcc accattcaga tattgatgaa catgaacaaa gaccagattg ccatcctcaa
    28261 tggtgcggac aatcttaatc tgacgctctg gatgacgctc aaagaaatct gcaaagaagg
    28321 ctgcaaatcc ttctttcccg tcaggaacac ctgtcgaatg ttggatatag gtagccccta
    28381 cagactgggc ttgagcctca gcaactcgtc cgtcttgaat ggcatggatg tataggttgt
    28441 gagcattttt cacttgttgt gacatattct aaacctcatt tcccttctct ttcagattcg
    28501 ccaaaattct ttcttgaaaa ccttcaaatt ggtgaatttc ttcctctgaa aatcctttgt
    28561 aaaagatagt atccaatttc tgactgacac gatgccccac ttctttctgg gacttgccta
    28621 actccgttaa aactaaatac ttcttacgct tgtcttttcc acacggacta acaattacaa
    28681 gcttttgttc ctctagcttt tttatcatag tcgtcagcgt attattcgca agtccagtcg
    28741 caagcgcgat atctgtcgca gttgcgcagc cagtttcact attccataaa accgctaaaa
    28801 tcttgccctg ttcaccccta taaagagcct caggatcttg actcagtaac ttttgaaaaa
    28861 tccgcccatt caacaaacga atatgatggg ctagcaaatg accatctttc ataacacctc
    28921 caatttattt cgatatcgaa atgaataaaa caattgtaac actcatcgtt ctaactgtca
    28981 actatttcga tttagaaata atttttgata attatccaca ccaccatact ccggctcaac
    29041 taacttttaa cgagagtttc taaactcctt cgtcctccag tctacaaaag ccttccatcc
    29101 gtactatcct atattttatg aggggacaca tttttcctat cagaccattt attttaaaga
    29161 tagaagtaaa tcataattgc ttccatctgt tcttttatag tatattgaag ttggactagg
    29221 gcactgtatc ttctaaaaca ttgatagaaa gcgatttgaa tttcccaatc aatttgttcg
    29281 tctttatagc atttcgaaac tgaaatagga caccatgact gctaaaagat ttctataaat
    29341 tcatttgatt tcctcaatca atttgttcat atcttatttc attccgctat aatttcacct
    29401 taccctatct ttttcgtagc acccttcaaa cagcctatcc cctaccgttt gacgattcct
    29461 cacttcactc cacttccatt acagaagttt cttcactact atggtctcgg ctgacttctc
    29521 atgattcctt gttactacta tttgaacgct cacgagatag gtcttataaa aaatgctttg
    29581 atccacaatg gaatcaaagc attttaaaaa gttcctcata cataagtgca gaagtcgcag
    29641 ttcctctgta cttggcttct tctcttttga taaagcgagc caagttgagc aactcaggtg
    29701 ctggatgttt gggatttagg agcaattcac gattgaccag gcctgagaga cgaactgcct
    29761 gcaattgctc atttgtagta ggcagttttt tagtagtctc taggagagca gcaactaaat
    29821 cttcactcaa atcatgtcga gcatgattgt aaagatcttt tataaggctt tctaggtttg
    29881 gttctgccat ccctaccacc tcccttatgg tttaataatg tttaatcaaa tcaaccgttg
    29941 aacgatccaa tttcttcacc aaggcttgta agaaagcttg cgcttctagg aagtcatcca
    30001 ttgcatagag ggtttggtga gaatggatat aacgagcgca gacaccgata gttgttgatg
    30061 ggacaccacc atttttcaga tgagctgcac ctgcatctgt tccgccttta ccacagtagt
    30121 attggtactt gataccagct tcttcagccg ttgtcaaaag gaaatccttc atccctggga
    30181 gaagcaagtg acctggatca tagaaacgaa tcaaggttcc atctccaatc ttgccttgac
    30241 caccgtagac atcacctgct ggtgagcaat caactgcgag gaagacttct gggtcaaact
    30301 tggttgtaga ggtatgagcg ccacgcagac caacttcttc ttggacgtta gaacccagat
    30361 agagttcatt gccgagtttt tgacctaata aagcttcagc tagctcgctt accatgagga
    30421 caccgtagcg gttatcccaa gcttttgaga tgatattttt ttcattggct gtcaaaattg
    30481 cagaactatc tggtacgatg gtatcaccag gacggatgcc aaaactttct gcctcagcct
    30541 tgtccgcaaa accaccatca aaaacgatat cggcaatggc tggcatggtt ggtcccccct
    30601 ttccacgagt caaatgcgga ggaacagaac ctgaaatcac aggaatttca tgaccatcac
    30661 gagtcaagag tttgaaacgt tggctgctaa ccaccatggg gttccagcca ccgatttcta
    30721 cgacacggaa ggtaccatct ggcttgattt cgctgaccat aaaaccaact tcgtccatat
    30781 gagaagcgac caagacgcgc ggtgcatcca cagcttctga atgtttgata ccaaaaatac
    30841 cacccaagcc atctgtcacc acttcatcca catgcggtgt caacttttca cgaagataag
    30901 cacggacagg cgcttcatga cctgagactg cagcaagttc tgttacttct ttaatttttg
    30961 aaaataatgt tgtcatttca gttccttctt tctttcatcc attttaccac tttttatagg
    31021 agaaggatag tgggaaggtg gatttctaag ttagtatctt agtcctgctc tatcttagaa
    31081 aaggatagta ttctcttgca tgtagtgcaa aatctagtaa acattccaaa attaactcga
    31141 atatttattt ccaaacaaaa aaacaataca ccatcaaagt tgtttggatt tttcatgaaa
    31201 tttacagaaa atagttgact tccctttctt ctttctttaa atatatagtt ggttgagttt
    31261 ggaatagtac gctgtagctg ctaaaacatt tctagaaatt aatttgactt ttctaataga
    31321 gttgttcata tcttatttca atttactata gtacaaaact agaaaaggaa aaaatcatga
    31381 ccaaaacaat tcttgttaca ggtgggacta gctacattgg ctcccatacc gttaaagctc
    31441 ttttaaatgc tggctatcag gtgcatgtcc tcgataatct ctccacagga aatcgagcgg
    31501 ctgtggatag tcgtgctagc tttaaagaac tggatgttta tgatgctagc gccttaaagg
    31561 cttacttaga agaaaatcag attgatgctg tcctccattg tgcaggtgaa attgttgtga
    31621 gcgaaagtat tgaaaatcca agtaaatact tcactgccaa cgttgctggt atggaccaag
    31681 ttctcaaagt cttatctgaa gttggcattc aaaaaatcat gttctcttcg actgcttctc
    31741 tctatggaaa taactgtatt gacaagccgg tgactgaaga taccctgctc gaccctgtca
    31801 acccttatgc agagacaaaa ctgatgggcg aacgaatgat ttactggatg gccaatcgct
    31861 acgactggaa atatgttatt ttccgttact ttaatgttgc tggggctgaa atggatgctt
    31921 caaacggtct gcgtgtgaaa aatccaactc acatcattcc aaatatcaac aagaccgcat
    31981 tgggacaaca tgatagctta aaaatatttg gagatgacta cgatacacgt gacggttcat
    32041 gtattcgaga ttacatttat gtcttggacc ttgcataggc tcatgttaaa ggaatgaact
    32101 acctatttca agaagacagt tcttctcaaa tctttaactt aggaactaaa aaaggctata
    32161 ctatcaaaga aatctttaaa actgctgaag aattactaaa ttaaaaaatc ccacacgaga
    32221 ttgttgctcg acgtgctagt gacccagcca gtgtcctagc agatgcttca aaagctaaac
    32281 aatatcttga ttggacggct agctactccc tcgaagatat tattttatca gattaaggta
    32341 aaaacatttt agaataggat aacaaaggag aaagtcttgt tgctctctcc ttgttgtatt
    32401 tattaaattg tcagaaattt tattgacaga ttagaaaaat aatgttacat ttatatccgc
    32461 aggtatcttt cgataccaaa tctacatgaa aggacggggt atgaaacttt ctcattattt
    32521 aattggctta cttctactcc tagtctttct ctctattagc attgggacca gtgatttttc
    32581 atggggaaag ctatttgatt tcgaccagca gacctggctc ctctttcaag agtcccgtct
    32641 cccaagaact atcagtattc tcctgactgc ctctagtatg agtatggcag gccttctcat
    32701 gcagactatt acccaaaatc agtttgctgc accgagtaca gttggaacga ctgaagccgc
    32761 caaactggga atggtgctga gcctttttgt ctttccatcg gctagtctga cccaaaagat
    32821 gctcttcgct tttatttcat ccatcgtatt caccctcttc ttcctagcct ttatgaccat
    32881 ttttactgta aaggaaaggt ggatgttgcc tctgattggg atcatctata gcgggattat
    32941 cggctcagtc acagaagtta tcgcctatcg tttcaatctg gttcagagta tgactgcctg
    33001 gacccagggc tccttctcca tgattcagac ccatcagtat gagtggctct tcttaggcct
    33061 catcatcctg ataaccgttt ggaaattatc ccaaaccttc accatcatga atctagggaa
    33121 agaaaccagc gagagtttgg ggatttccta ctccctactt gaaaaactgg ccctctttct
    33181 ggtggcgcta acgacaagcg tcaccatgat taccgtgggt ggcttaccat ttctcggagt
    33241 tatcgttccc aatcttgttc gcaagcgcta tggagataat ctaagtcaaa ccaaactcat
    33301 ggtcgcactg gttggtgcca atctagttct ggcttgcgat atcctatccc gagttctgat
    33361 taggccctat gagttgtctg tcagtctctt gctaggaatc atcggtagtc tcgtctttat
    33421 cctacttctc tggagagggg gacgaaaaga tgcagactaa aagcaaacat accaagctct
    33481 tctggattct cattattctt gccatcggag cttgtcttct ctacttttgg cccatcactc
    33541 acttgtcagc ctttgcttgg aagttgcgtt cccaaaagat catcgtttat ctcttggtag
    33601 ccatcgcgac tgggatttcg accattagtt ttcaaaccct gacggaaaat cgcttcctga
    33661 cgcctagtat tttgggaatt gaatccttct acgtcctact acaaacccta ctactggttt
    33721 ttgaaagcaa gtttcttcaa cttggcaaat cccctatctt agaattccta gtcttacttc
    33781 ttgtccagtc cctcttcttt ctcgccttac aaggttactt gaagacactg atgaagcaag
    33841 acctggtctt catcctgctg atctgtctag cgctcagaag tctctttcga aatatcagca
    33901 ccttccttca agtcctaatg gatccaaacg aatacgataa actgcaaaat agtctttttg
    33961 cctcctttca acatcttaac acttccatcc tagccatcgg ttctctgatc atcctcgctt
    34021 tgacaatctt tttctttcga aaagcagtcg ttctagatgt cttgcacctg caaagagaaa
    34081 cggctcagat attgggactc gatgttgaaa aagaacagaa agagctcctc tggggaatcg
    34141 tgcttttgac ctcaacggcc actgccttgg taggacctat ggccttcttc ggctttatgc
    34201 tggccaacct cacctacctg attgtcaaag actatcagca caagttactc tttatagtgg
    34261 ccattctggt tggatttatt agcttaacct tggggcaagc cttgattgaa cgagtctttg
    34321 cactggaaat tcgtatcagt atgatcattg agagtgtggg tggcttctta ttctttatct
    34381 tactatatag gagggctcgt cagtgaaact ggaaaacatt gacaaatcca ttcaaaaaca
    34441 ggatattttg caaggcattt cgcttgaagt cagtcctcaa aaactgacag cctttattgg
    34501 tccaaatggt gctggaaaat cgactctcct ctccatcatg agcagactaa ccaagaaaga
    34561 tcagggagtt ctcagtatca aaggacgtga aatcgagagc tggaattcgc aagaactggc
    34621 ccaagaacta accatcctaa aacagaaaat caattaccaa gccaaattga ctgttgaaga
    34681 actggtcagt tttggacgtt ttccctacag ccgaggtcga cttagatcag aagactggga
    34741 aaaaatccga gaaactctga actatttgga actgaccaac ttaaaagacc gctacatcaa
    34801 tagcctgtca ggggggcaac tccagcgcgt ctttatcgct atggtactgg cccaggatac
    34861 ggactttatc ttgctggacg aaccactcaa caatctcgat atcaagcaaa gcgtcagcat
    34921 gatgcagatt cttcgacgac tggtggagga actcggcaag accattatca tcgtcctcca
    34981 cgatatcaac atggccagtc agtatgcaga tgaaattgtc gccttcaagg acggccaggt
    35041 ctttagcaag ggaagaaccg atcaaatcat gcaggctgac ctgctcagtc aactttatga
    35101 gattcccatc acgctagctg atatcaataa caaaaagatc tgtatctata gctagtaaca
    35161 taaaagctca agttagagaa ccttcagtct cttagtcaat aagattaaga gactccctaa
    35221 atcgttatca cattttaaaa aggagaaatt atgaaaacat cccttaaact ttatttcact
    35281 gccctagtgg ccagcttctt gctcctactt ggtgcatgta gtacaaactc aagcactagt
    35341 cagacagaga ccagtagctc tgctccaaca gaggtaacca ttaaaagttc actggacgag
    35401 gtcaaacttt ccaaagttcc tgaaaagatt gtgacctttg acctcggcgc tgcggatact
    35461 attcgcgctt taggatttga aaaaaatatc gtcggaatgc ctacaaaaac tgttccgact
    35521 tatctaaaag acctagtggg aactgtcaaa aatgttggtt ctatgaaaga acctgattta
    35581 gaagctatcg ccgcccttga gcctgatttg attatcgctt caccacgtac acaaaaattt
    35641 gtagacaaat tcaaagaaat cgccccaacc gttctcttcc aagcaagcaa ggatgactac
    35701 tggacttcta ccaaggctaa tatcgaatcc ttagcaagtg ccttcggcga aactagtaca
    35761 caaaaagcca aggaagaatt ggccaagcta gacaagagca tccaagaagt cgctactaaa
    35821 aatgaaagct ctgacaaaaa agcccttgcg atcctcctta atgaaggaaa aatggcagcc
    35881 tttggtgcca aatctcgttt ctctttcttg taccaaacct tgaaattcaa accaactgat
    35941 acaaaatttg aagactcacg ccacggacaa gaagtcagct ttgaaagtgt caaagaaatc
    36001 aaccctgaca tcctctttgt catcaaccgt acccttgcca tcggtgggga caactctagc
    36061 aacgacggtg tcctagaaaa tgcccttatc gctgaaacac ctgctgctaa aaatggtaag
    36121 attatccaac taacaccaga cctctggtat ctaagcggag gcggacttga atcaacaaaa
    36181 ctcatgattg aagacataca aaaagctttg aaataagcca cttcaaactc aatttaatac
    36241 tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gttgctcaaa acactgtttt
    36301 gaggttgcag atgaaagctg atgcggtttg aagagatttt cgaagagtat aaaattttga
    36361 cattctaaaa cgcatcctat caagttcact caaacctgat aggatgcgtt tttatcattt
    36421 tgaaatctat ttaccccacc tcattcccct tcttgatttc gtttaaggga aaagtggtct
    36481 ggaacggggt ccttacctgt tttcgaccag ggatgacaac gtaaaatccg agccaagccc
    36541 atcaataccc ccttaaaacc atgtttttca atagcctgaa tcatgtagtt ggaacaagtc
    36601 agctcaaagc gacaagaggg tggaaagact ggtgagataa aacgttggta aaagcgcaca
    36661 agcgctatta aaattcgttt cattatttct tagttacagc catggtgtgt agttggctga
    36721 tttctttttt attaagacga cgggattctc ctggacggag tcctgtcaag tctaggtgtc
    36781 cgaaacgagt ccgagacaac ttatctactt ggagaccaac agcttcaaac atctttttaa
    36841 cctgatggtt acgcccttca tggatggtca actgcaccac agagcgattt ttgactgggt
    36901 ccactttgag aatttcataa acagctggct tggttttctt accatcaatc tcaagaccac
    36961 gggtcaaggg gcgaagattg tccttattgg ccacaccttt aacacgcgcg acataaacct
    37021 tgtcaatctc attacgaggg tgaatcatct cgtctgtaaa gtccccatca ttggtcaaaa
    37081 tcaagactcc tgatgtatcc cagtccaaac gacccacagg gtaaatgcgc tctttgacat
    37141 tgggcaagag gtcgacaacc gtcttgcgac ccttgtcatc tgttacactg gaaatgacac
    37201 cgcgtggttt gttaagcaga taatagacct tttcttcgtt gtagataggt tgaccttcaa
    37261 cttcgacctt gtcgcctgac ttgatagtgg ttgctagttc acgcaccact tggccgttaa
    37321 ctgtcaccaa accttgcttg atcagctctt ctgcttttct cctactggcc acacctgcgt
    37381 gggcaatata cttattgatt ctcatcttct tctatccttt caccaaataa ttggctttct
    37441 tgggcttgaa tctcaagctc atcaatcact ggtaattctt ctaaatggtt tatccccatg
    37501 taatctagga aataatccgt agtcacatag aggttggggc gccccaatac ttcctttttc
    37561 ccgtcttcct ttatcaggtc caaagcttgc aactttgcca aggctccact cgagttaacc
    37621 ccacggatgg catcaatttc tatccgcgta atcggctgtt tgtaggcaat aatggacaag
    37681 gtctcaaggg cagcccgaga caagctctgg ttgataggcg ccttagagta ttccttcaaa
    37741 atctctgcaa attgaggctt ggtcaccaat ctataagcac cacttgtctc aatcaaagcc
    37801 aaactggaat ctgggtcctt ttcatacttc tgggctaatt ttcctaaact ttgctggatg
    37861 cctgtcggtg gcagagagag gagttcagct aactggcgga cccgaatccc atcttcaccc
    37921 gctacaaaca agagcgcttc tatttttgct aaagtactca tctttcctct ctatcaagtc
    37981 tagctttgag gcacttgact ttcttccttc ttttccatga gatagatatc tccaaaactc
    38041 tcctcttgca cgaggatcag ctcctgggtt ttgattaact ctagggttgc caaaaagagg
    38101 gtgatgacct cttggacatt ctgggcttcc ttgaacaaat cctgcaagcg caattgatct
    38161 cgtccaatca aggattcttt cacaataatc atcatgtcct caatcttata ctcatcccgc
    38221 aagatagtcg tgtgattttg tgcaaactcc tcttttttct tggctaggat atttgaaaaa
    38281 gccaaaaaga ggtcaatggt cgtcttgtca tgcacaagct ccgcatcttc gtaaatcaac
    38341 tctgtcggcg ctttggaata atactgggcc cgttcttggt gcttggcttc caagtgctca
    38401 cccaagagct tgaacttgcg atattcttcg atttgagaga ggaggtcctg ctccaggtca
    38461 tcccccaagt ctgtcacttc tgctaccttc ggaaggagtt tacgactctt aatcagcatg
    38521 agctgactag ccatgaccat gtactcaccc gtcacttcca gacgcatggc ctgcagggtt
    38581 gagacatagg ctagatactg ttcgatgact tccgtaatgg gcacatcgta gatatccatc
    38641 tggtacttag aaaccagatg caagagtaag tccaggggtc cttcaaaatc ttttaattta
    38701 atatccatta tctatatttt tctaaggtca ggactgtttt taatcctaat ttttttgcaa
    38761 tttcgtacaa atcgaccttg ttttctattt gtcttagaat aaactgttca cgtaagactt
    38821 gagctgataa ggatggaaaa cctttctcct tgacaaaaga ttctaactga cgaaaggccc
    38881 actgacgaga atagggtttc cctcctcttt caaaaagata ggtctgcccc atcaagggtt
    38941 ccaattctga aagcaaggcc gtgggaatgg tgacaatcct ccgttgggaa gccttgctga
    39001 ttcgcaacac ctgaaaatcc agattgatgt ccgcaacctt gatggctaaa atctcactgg
    39061 gcaagagccc catttctagg attaagagcg ctagcaagcg gccctctgga tggtcgcttt
    39121 cctgccaaaa agagtctagg tatagaatct ctggcttttc cgtcttcttt tcagcttgtt
    39181 tggctaattc caagcggtaa aagctgtcca cctctccttt ttgatagaga aagtatagaa
    39241 attggttaca ggccgaaatc tttcgcttct gggcgctgat ttttagattg gctagctggg
    39301 cttggtaaat cttgagactg gtctcagaaa tccgctcacc taccatgtct aaaaattgct
    39361 ccaaatcata cttataggac tgcttggaat tgacagacaa gccctgcttt tcctctaaaa
    39421 aggctgaaat cctgtctctc attggcatcg aatctcatat tccttactaa agtcatgcaa
    39481 gagggcatta acggccttga ggatggactt gcgcgtaata atcccttgga aaataccctc
    39541 tgcatccaca accggtaaga aggactcatc tactagcttg tgcaagacct ccgtaatggt
    39601 gaaatcaggc gaaacaaccg ctacgtccgt ttttgtcata tgaacgatat ccgtatccgc
    39661 catgatttct tggctcaagt catgctccat ctgataagcc ataatatctc tgagtccaat
    39721 cgtcccaaca aactgttttt catctgtcac aacgggaaca cgggtatagg tcatctgact
    39781 gagcaagagg gtcgcatgat ccgcattgtg agtatcaatc aacacagcta gatttttagc
    39841 aggggtcaaa aaagtttcct cctgccccaa caagaaagtc tcaaactcct tggcaatcat
    39901 cggctaaact ccttggacaa acctggatac acctcgtgat ctcgtgtcaa aaagtccact
    39961 ttgaagtaac tatcatcaat ctccacacga gcatagagac attctctgat ggtacctcgt
    40021 ggttgactga tagagcctgg atttagaaag aggatcttgc cttccaacca agcacttggc
    40081 acatgcaagt gaccatagag gcagatagcg gcctcttcct cctgagccca gtagtccaac
    40141 ttttgaaagt tgaaattgat gtcaaacaag tgaccatgag tttggataat cttggtcgaa
    40201 ccaagctcag tcaccagacg ttctgggtag ccggcgtaga agtccatgtt ccctttaaca
    40261 acgcggatgc cctcccaaag tggagaatcc ggacgtagtt cagaatcgcc gttatgaaaa
    40321 acggcatcga ctttgcccac atagcgatca cggacttctt ccacaatcaa gctatcgcca
    40381 tgggaatcgc tcattacaat gatggtttgc tttgccatga tggaaatacc tccaaaagtt
    40441 tcttaacggc taaggcacgg tgagattgac tatttttttc ttccagggtt aattcagctg
    40501 atgactcacc tgtctctcct acaaggaaga ggggatcata gccaaagcca ttttcaccct
    40561 taggttcaaa gttaatataa cctgaccagt ctgcttcaac aactaaactt tccttatttg
    40621 ggctggctac gactagggtt gtgtggaact gagccgagcg gtccttgagt tcaaagacca
    40681 tggccaattc gtgcaagagt ttggcattat tttcacggtc agttgctccc acacctgcga
    40741 aacgagctga ccagacgcct ggtaagccac caaggacatc gactttgaga ccagaatcat
    40801 ctgccaaaac catcttgccc gttaattgag aaatggtttc tgccttaagg cgggcatttt
    40861 cctcaaaggt catacctgtt tctgctactt caggcaggtc agggtagtca ttaagatttt
    40921 ccacatcgta gcctaactta tcaaagatag ctcggaattc cttggtttta ccttcgttac
    40981 gagtcgcaat caacaaggtt tctctgactt tgcttgtctc aaagaaatca tgaacattga
    41041 ccccttcttt aggcaattct acatacaaga gttgcccatt ttcaaccaag agcagggccc
    41101 catgacgttg aataacttcc aagtttcgtc ccatttcttg attaagcata tctaccacaa
    41161 aggagaacaa acggtaggta gaaccatagc gtaaaacagt aactgaaagc gggaaaccat
    41221 actcttcatc tccaaatatt ttggagaatt caaacagagg aaaatctgtc tgatagtcgc
    41281 tcaaactgtt aacgccacca aaaatactat aagacccaac ataccagtcc tggtcatcct
    41341 tatattcata aattttattt gtcataattc tacatgctcc acatgaatct ctttttccag
    41401 ccattcttca ccaatttgtg caaaactttg gctactggct gttgtgtaaa aacggtgatg
    41461 gagtggtcca gcatcgcgac cacgattgat ttcaaaataa ttgagtaaga ctgagatatc
    41521 ccgtacgcac tctgccccac tatcgatgag ctgaaccttt ggccccatca cattttggat
    41581 aatagggcga aggagtggat aatgagtaca gcccaaaatc aggctatcca cctttccaac
    41641 caagggacgc agggtttcat agaccacctt cttggtaaca ctggttgaca gggcacctga
    41701 ctcaaccaag ggagcaaact tgggacaggc caagctctcc acctgtaagt cgggatccag
    41761 atcatggatt ttctgacggt atatgtctga ttgtaccgtc atgggcgttc caatcactcc
    41821 gattttccca ccttgactgg acttgatggc tgccgaagct cctggcaaaa ttacacccaa
    41881 gacaggaata tctagttgag ccttgatttc ttcccagacg accgcagtcg cagtgttaca
    41941 agcaatgaca atcattttga catccttggt caagagaaag ttgaccagct gccaagtata
    42001 ttcacgaatt tgctcagcag gacgggggcc atagggcgcc cgcgccgaat ctccaatata
    42061 gacgatttct tcatggggaa gctggcgcat gagctcgcgc acaacggtca agcccccgac
    42121 acccgaatcc aaaaaaccaa ttggtcgatt atccatacag tcttctttct agtctttttt
    42181 ctgattgatc gttcattatg attccttgta ctgaacgaac tgaccgacag cttgatagaa
    42241 tgtcaactac ctctctctta atcataatca aatatcaata gaatgcaagg aaaaagtctc
    42301 atccctaaac cataaccaac atagtgagaa gtctggaact ttcatcccag acttttcctt
    42361 atttattttt tctttttatt gttagcaagg gctgcctttt gttggcggat gatttggtgg
    42421 taaacttgtt gtaccttagc ttcgcttggt ttttgaccat ttgcactcaa aagagtacga
    42481 actgcttcag cattcaaacg tgggttgtca gcaaattctt tttcgatttg cttacgaacc
    42541 aagtacattc ctccaagagc tcctcctaga aaagctagca caatcaatac aattgctaaa
    42601 agtaaatcca tcatttttct cctgtttctt tttgaatccc tttcattata ccacaaacta
    42661 gccaccctga ccagtttgtt ctacactttc agggatggaa tagacagcaa aaagaaccct
    42721 gcttttctga aaaagaggtc tccttgctaa gtttatactc aatgaaaatc aaagagcaaa
    42781 ctaggaagct agccacaggt tgctcaaagc accgctttga ggttgcagat aaaactgaca
    42841 cggtttgaag agattttcga agagtattaa tttacataaa tagccagtgt ttgatagggt
    42901 ttgagtagaa ttttctcaga cacttctgca tcttcatagt ttgatatcaa aatctgtcca
    42961 ttttggtaga ctgctggcaa gtcgatttcc acttctttag cataaaagtt attgagcact
    43021 agtaactttt gatcctcaaa ctggcgttca aaagcgtaga cttgtttgct atcttcaaag
    43081 gctggtttgt aacttccttc tgaaatgatt ggcatttcct tacgcagtcg aatcaagtct
    43141 tgatagaagg tgaaaatcgg accctggatt tcattttcta cattgatgta tttataggat
    43201 ttaccagctt tcaaccatgg agtgcctgtt gaaaatcctg cattttccga agcatcccac
    43261 tgcatgggaa tgcgtgaatt atcacgcgac ttagcttgaa taatctggaa ggcttcttgc
    43321 tgactctttc cttcttctaa gagcgtctga taggcattaa gcgattcgac atccacataa
    43381 tcagccatag aatcatagtc tgggtcaatc atcccgattt cttcacccat atagatataa
    43441 ggtgtcccac gtgacaggtg aatgctagcc gctagcatgg tggctccttc cttgcggaag
    43501 ttttgaatat cgacaaaacg gttcaaggca cgtggttgat cgtgattgtt ccaaaagagg
    43561 gcactccaac cgtctttatc actcatttcc ttaccccaac tatggtaaag actcttcaac
    43621 tcttcaaaat caaagggagc caaggtccac ttttgtccat ccttatagtc caccttgagg
    43681 tgatgaaaat taaaggtcat ggataattcc tgacgatcag gcgacgaata gaggacacag
    43741 ttttccatgg tggtagaaga catttcccca actgtcataa agctatcgtc agatccaaaa
    43801 gtggcttggt tcatcatacg caaatagtta tgaacgatgg gtttgtctgt ataagctggc
    43861 ttcccttcat tttcaggaca gtccactgaa acctcgtcct taccgatcaa attgatcaca
    43921 tcaaatcgga aacctttgat acccttgtcg cgccagaaat taacaacctt gaaaagctcc
    43981 ttacggacat tggaattgcg ccagttaagg tcagcctggg tctcatcaaa taggtgaaga
    44041 tagtatttcc cagtatcccc gaaaggcgtc catgcagaac caccaaactt agactgccaa
    44101 tctgttggtt ggtcttggat gaagaaaaag tcttgataat acttatcacc agctagggct
    44161 ttctgaaacc attcatgctc tgtcgaacaa tgattaagta ccatgtccag cataaagtca
    44221 atcttgtgct ctttaccgac acacaccatt tcctcaaaat cagccatatc accaaaaaga
    44281 ggatccactg ccatataatc tgaaatatcg taaccattat cccgttgagg gcttggatag
    44341 aatggattga gccagaccat atccacacct agtttggcta aatagggaat tttttcgata
    44401 atcccacgga aatccccaat accgttttca gtggtgtctt tgtaagattt tggatagatt
    44461 tgatagacta cttttccttt atcaagtgtc atctgtttct ccttttctga taaaagggag
    44521 gaagcagtct tccgtcccta tttgtgctat ttcaattata ctcaatgaaa atcaaagaac
    44581 aaactaggaa gctagccaca ggttgctcaa aacactattt tgaggttgca gatagagctg
    44641 acgtggtttg aagagatttt cgaagagtat tagattcgtg tagcgaccat gagagatgct
    44701 ccagcttgga tcgttgtcgg ataagttccg ggaatagtcg ctgtataagc atcttggttg
    44761 gtgatgataa caggagtttc tgtcaccaga cctgcagcct taatgacatc catatcaaaa
    44821 cgaatcagtt gctgaccaac tgtaacgtga tctccttgga ctacaagact ttcaaaacct
    44881 ttgccatcaa gacctactgt atccataccg atgtggatga gcaattcaac tccctcgtca
    44941 gagacaatgc cgatggcatg cttggtaggg aaaagaaccg tcactgtccc attaactgga
    45001 gaggtcaact caccttggct tggttcaatg actagacctt gccccatgac acctgatgca
    45061 aaaataggat ccgtcgcttg actcaattct ttcacttggc cagttagtgg gctgataatt
    45121 tctaccgaag taagttctac tggttcatgg ttcacaaatt ctgcttcttc ttgagcaacg
    45181 aattctgcct gcaagttcgt atcgccctct gtttttgtaa agagaccagc cttgcggaag
    45241 aagaaagtca agagcattgg aacaacaatc gcaactagca tagttcctgc aaatggcagc
    45301 atgtattgag gttgaataga gagaatacct ggcaaaccac cgataccaat agaagccgca
    45361 gttacattaa aagtaacgga taacatgcct gcaagggctg aaccagtcat cccagcaaca
    45421 aatggataaa tatattttac gttaacccca aaaagagctg gttctgtaac accgagatag
    45481 gctgaaatgg ttgcaggaag tgaaacctga gcctcacgct catcatggcg atgcatgaaa
    45541 taatagacaa acacggctga gccttgagca atattagaaa gagcaatcat tggccatagg
    45601 gcagtgccac cagcatccgc aatcaattgt gtatcaatgg cattggtcat atggtgcaga
    45661 cctgtgatga caaatggagc gtagagggca ccaaaaattg caccgaagag ccatttaact
    45721 ggaccagtta aacctgccaa gacaactgat gaaagtcctt gtccaattgt ccaaccgatt
    45781 ggtcccaaaa cagtatgagc caaaatcaag gctggaatca atgacaagaa aggtacaaaa
    45841 atcatagaaa tgacttctgg gatatgcttg cgccagaaga tttcaagata agacagactc
    45901 aaacctgcaa gcaaggctgg gataacttgg gcttggtaac cgatacgatt aacagtaaaa
    45961 tagccaaaat tccaaaccca gtttgccgcg atatcagctg ctggcgttga agcaaccgca
    46021 taggcattga gcaactgagg cgataccaaa cagattccga gaacaattcc caaaatttgg
    46081 ctggttccca tcttacgaga aacagaccaa gtaatcccta ctggtaagaa ctggaagata
    46141 gcttcaccag gcaaccagag gaagtgattg acacctgccc aaaactgaga ggattctgtg
    46201 atggtcttgc catccaacat cgaccaatgg acaccttcca agacattacg gaaaccgagg
    46261 atcaatcctc cgactatcaa ggctggaata atcggagtaa aaatctccgc cagagtggtc
    46321 ataacacgtt ggaccacgtt ttgattactc ttagctgcag acttggctgc ttctttggaa
    46381 acaccctcaa tacctgaaac ggctgtaaaa tcattataaa agatgggcac gtcatttcca
    46441 atgattacct gaaattgacc tgcatttgta aaagttcctt taacagctgg aattgactcg
    46501 atagctttaa cattagcctt cttatcatct cctaaaacaa agcgcatccg tgtcgcacag
    46561 tgggtgacgg cagtcacatt ttctttgcct ccaattgcct gaagcagatc tttggcttct
    46621 tgttcaaatt ttcccatttg attctcctta tacttgtcaa agcaagtttg atttgataag
    46681 tatattgtaa acgataccaa acttgtctgc aacttgtttg gtataaaaag ggtgtttttt
    46741 tgtaaatttt ctagcacttg tatggtaaaa tagatacagg tgttcattaa actagactaa
    46801 aaacctattt aagcaggcaa aatgaagaaa taccaacaat tatttaagca aatccaagaa
    46861 accattcaaa acgagactta cgctgtcgga gatttccttc ctagcgagca cgaccttatg
    46921 gagcaatatc aagtgagtcg tgataccgtc cgaaaggccc tgtctctcct ccaagaggaa
    46981 ggattgatca aaaagataag agggcaaggt tctcaagtcg tcaaagaaga aaccgtcaat
    47041 ttccctgtat ccaacctaac cagctaccaa gaactagtta aagaacttgg actgcgctct
    47101 aaaaccaacg tggtcagtct ggacaagatt attattgata aaaaatcctc actgataacc
    47161 ggtttcccag agtttcggat ggtttggaag gtggtccgcc agcgtgtggt ggatgatctg
    47221 gtatccgttc tggatacaga ctatctggat atggaactaa ttccaaatct cactcgccaa
    47281 attgctgagc agtctatcta ttcttatata gaaaatggcc tcaaactcct tattgattat
    47341 gctcagaagg aaatcaccat tgaccactca agcgaccgag acaagattct catggacatt
    47401 ggcaaagacc cttatgtcgt ttcgattaaa tcaaaagtct atctccaaga cggacgccaa
    47461 tttcagttta ccgaaagtcg ccataagtta gaaaaattta gatttgtaga ttttgcaaaa
    47521 cgcaagaaat aaaagactga gacaccagat ctcagccttt ttcggctcta taatatttgt
    47581 agtgggtaac ccccctatgg atattatgga gcctattttg tgtagaaaaa aagtcccata
    47641 tgacctataa tgaaaagcga caaaacaact cattagaaag aatcatatgg aacaattaca
    47701 ttttatcaca aaattactag acattaaaga ccctaatatc cagattttag acatcatcaa
    47761 gaaggataca cacaaggaaa tcatcgccaa actggactat gaagctccat cttgtcctga
    47821 gtgcggaagt caaatgaaga aatattactt tcaaaaacct tctaaaattc cttatcttga
    47881 aacaactggt atgcctacta gaattctcct tagaaagcgt cgtttcaagt gctatcattg
    47941 ttctaaaatt atggttgctg aaacttctat cgtcaagaag aatcaccaaa tccctcgtat
    48001 catcaaccaa aagattgctc aaaagttaat tgaaaagatt tctatgactg atattgccca
    48061 tcagctttcc atctcaactt caactgtcat tcgaaagctc aatgacttcc actttgagtg
    48121 taattttaga aatctgccta agattatgtc ttgggacgtt gaaacagtcc ggggagtgac
    48181 tgtttcaatc gggagatgga gatgagcttt attgcgcaag attttgaaaa gctcgatatc
    48241 atcactgttc ttgaaggtag aacacaagct gccatccgag atcactttct taaatatgat
    48301 agagccgtcc gatgtcgcgt caaaatcatt actatggata tgtttagccc ttactatgac
    48361 ttggctaaac agcttcgctt tcaaatttct aggctcaggc tgaaacagtc tcccagactg
    48421 tttcactccc gaatgctgaa atcgttcttg atcgctttca cattg
//
LOCUS       DAVKEV010000011        47455 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVKEV010000011 DAVKEV010000000
VERSION     DAVKEV010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.011"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            41..388
                     /locus_tag="VWZ68_000614"
     CDS             41..388
                     /locus_tag="VWZ68_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9371687.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEIEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(505..1638)
                     /locus_tag="VWZ68_000615"
                     /pseudo
     CDS             complement(505..1638)
                     /locus_tag="VWZ68_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            1703..1984
                     /locus_tag="VWZ68_000616"
     CDS             1703..1984
                     /locus_tag="VWZ68_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEU9371688.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGVDLLGYTTWS
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            2116..3060
                     /gene="manA"
                     /locus_tag="VWZ68_000617"
     CDS             2116..3060
                     /gene="manA"
                     /locus_tag="VWZ68_000617"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEU9371689.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(3100..4435)
                     /locus_tag="VWZ68_000618"
                     /pseudo
     CDS             complement(3100..4435)
                     /locus_tag="VWZ68_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            4663..5412
                     /locus_tag="VWZ68_000619"
     CDS             4663..5412
                     /locus_tag="VWZ68_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU9371690.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            complement(5432..5887)
                     /locus_tag="VWZ68_000620"
     CDS             complement(5432..5887)
                     /locus_tag="VWZ68_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU9371691.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(5907..7082)
                     /locus_tag="VWZ68_000621"
     CDS             complement(5907..7082)
                     /locus_tag="VWZ68_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU9371692.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITELEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(7141..7986)
                     /locus_tag="VWZ68_000622"
     CDS             complement(7141..7986)
                     /locus_tag="VWZ68_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU9371693.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEDGGLLM
                     GYEID"
     gene            8111..8668
                     /locus_tag="VWZ68_000623"
     CDS             8111..8668
                     /locus_tag="VWZ68_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU9371694.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            8687..9154
                     /locus_tag="VWZ68_000624"
     CDS             8687..9154
                     /locus_tag="VWZ68_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEU9371695.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            9243..9872
                     /gene="upp"
                     /locus_tag="VWZ68_000625"
     CDS             9243..9872
                     /gene="upp"
                     /locus_tag="VWZ68_000625"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEU9371696.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            10046..10636
                     /gene="clpP"
                     /locus_tag="VWZ68_000626"
     CDS             10046..10636
                     /gene="clpP"
                     /locus_tag="VWZ68_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEU9371697.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            10715..10963
                     /locus_tag="VWZ68_000627"
     CDS             10715..10963
                     /locus_tag="VWZ68_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEU9371698.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            11064..12224
                     /locus_tag="VWZ68_000628"
     CDS             11064..12224
                     /locus_tag="VWZ68_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9371699.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVIDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGRDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            12492..13361
                     /locus_tag="VWZ68_000629"
     CDS             12492..13361
                     /locus_tag="VWZ68_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU9371700.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGAISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFEMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            13365..14321
                     /locus_tag="VWZ68_000630"
     CDS             13365..14321
                     /locus_tag="VWZ68_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU9371701.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            14321..15085
                     /locus_tag="VWZ68_000631"
     CDS             14321..15085
                     /locus_tag="VWZ68_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9371702.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKDKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            15085..15795
                     /locus_tag="VWZ68_000632"
     CDS             15085..15795
                     /locus_tag="VWZ68_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9371703.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            16154..16810
                     /locus_tag="VWZ68_000633"
     CDS             16154..16810
                     /locus_tag="VWZ68_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU9371704.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQELHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            16918..18013
                     /gene="prfB"
                     /locus_tag="VWZ68_000634"
     CDS             join(16918..16989,16991..18013)
                     /gene="prfB"
                     /locus_tag="VWZ68_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEU9371705.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            18031..18723
                     /gene="ftsE"
                     /locus_tag="VWZ68_000635"
     CDS             18031..18723
                     /gene="ftsE"
                     /locus_tag="VWZ68_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEU9371706.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            18716..19642
                     /locus_tag="VWZ68_000636"
     CDS             18716..19642
                     /locus_tag="VWZ68_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9371707.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYYKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            19928..22108
                     /locus_tag="VWZ68_000637"
     CDS             19928..22108
                     /locus_tag="VWZ68_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU9371708.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            22160..22975
                     /locus_tag="VWZ68_000638"
     CDS             22160..22975
                     /locus_tag="VWZ68_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU9371709.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYNRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            23115..24458
                     /locus_tag="VWZ68_000639"
     CDS             23115..24458
                     /locus_tag="VWZ68_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9371710.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLESNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLEIVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDRNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            24835..26025
                     /locus_tag="VWZ68_000640"
     CDS             24835..26025
                     /locus_tag="VWZ68_000640"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEU9371711.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVINK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            26578..27513
                     /locus_tag="VWZ68_000641"
     CDS             26578..27513
                     /locus_tag="VWZ68_000641"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEU9371712.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            27547..28584
                     /locus_tag="VWZ68_000642"
     CDS             27547..28584
                     /locus_tag="VWZ68_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU9371713.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            28757..29362
                     /locus_tag="VWZ68_000643"
     CDS             28757..29362
                     /locus_tag="VWZ68_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEU9371714.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            29519..30049
                     /locus_tag="VWZ68_000644"
     CDS             29519..30049
                     /locus_tag="VWZ68_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEU9371715.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            30070..31155
                     /gene="rlmN"
                     /locus_tag="VWZ68_000645"
     CDS             30070..31155
                     /gene="rlmN"
                     /locus_tag="VWZ68_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEU9371716.1"
                     /translation="MKPSIHSLVHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFVCTINDDKGMAIGARHITISTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            31155..31637
                     /locus_tag="VWZ68_000646"
     CDS             31155..31637
                     /locus_tag="VWZ68_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU9371717.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKVRN
                     "
     gene            31639..33180
                     /locus_tag="VWZ68_000647"
     CDS             31639..33180
                     /locus_tag="VWZ68_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9371718.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(33236..34039)
                     /locus_tag="VWZ68_000648"
     CDS             complement(33236..34039)
                     /locus_tag="VWZ68_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU9371719.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(34122..34343)
                     /locus_tag="VWZ68_000649"
     CDS             complement(34122..34343)
                     /locus_tag="VWZ68_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371720.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            complement(34822..35019)
                     /locus_tag="VWZ68_000650"
     CDS             complement(34822..35019)
                     /locus_tag="VWZ68_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371721.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKRNMDLLADD
                     SLAGDIILLWRIQFGTFTTET"
     gene            35189..35461
                     /gene="rpsP"
                     /locus_tag="VWZ68_000651"
     CDS             35189..35461
                     /gene="rpsP"
                     /locus_tag="VWZ68_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEU9371722.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            35481..35720
                     /locus_tag="VWZ68_000652"
     CDS             35481..35720
                     /locus_tag="VWZ68_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEU9371723.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            36297..37085
                     /locus_tag="VWZ68_000653"
     CDS             36297..37085
                     /locus_tag="VWZ68_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9371724.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELLE"
     gene            37116..37634
                     /gene="rimM"
                     /locus_tag="VWZ68_000654"
     CDS             37116..37634
                     /gene="rimM"
                     /locus_tag="VWZ68_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEU9371725.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            37624..38343
                     /gene="trmD"
                     /locus_tag="VWZ68_000655"
     CDS             37624..38343
                     /gene="trmD"
                     /locus_tag="VWZ68_000655"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEU9371726.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRVQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            38355..38693
                     /locus_tag="VWZ68_000656"
     CDS             38355..38693
                     /locus_tag="VWZ68_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371727.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(38724..39044)
                     /locus_tag="VWZ68_000657"
     CDS             complement(38724..39044)
                     /locus_tag="VWZ68_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371728.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            39142..39357
                     /locus_tag="VWZ68_000658"
     CDS             39142..39357
                     /locus_tag="VWZ68_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEU9371729.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(39516..39602)
                     /locus_tag="VWZ68_000659"
                     /pseudo
     CDS             complement(39516..39602)
                     /locus_tag="VWZ68_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(39653..40189)
                     /locus_tag="VWZ68_000660"
     CDS             complement(39653..40189)
                     /locus_tag="VWZ68_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEU9371730.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            complement(40386..41732)
                     /gene="gor"
                     /locus_tag="VWZ68_000661"
     CDS             complement(40386..41732)
                     /gene="gor"
                     /locus_tag="VWZ68_000661"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEU9371731.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGLYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            42018..43217
                     /locus_tag="VWZ68_000662"
     CDS             42018..43217
                     /locus_tag="VWZ68_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEU9371732.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            43201..43902
                     /locus_tag="VWZ68_000663"
     CDS             43201..43902
                     /locus_tag="VWZ68_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9371733.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            43904..45163
                     /locus_tag="VWZ68_000664"
     CDS             43904..45163
                     /locus_tag="VWZ68_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9371734.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            45287..47284
                     /gene="metG"
                     /locus_tag="VWZ68_000665"
     CDS             45287..47284
                     /gene="metG"
                     /locus_tag="VWZ68_000665"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU9371735.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLDKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
BASE COUNT        14504 a         8804 c        10289 g        13858 t
ORIGIN      
        1 aaagatcgga gcaatccggt ctttttatgg aggagagtaa atgaatttaa atcaattaga
       61 tattatcgtt tcaaatgttc cccaagtctg tgctgacttg gagcatatct tggataaaaa
      121 ggcagattat gctgatgatg gttttgctca gtttacgatt ggtagtcact gccttatgtt
      181 gtcacaaaat catttggttc ctttggaaaa ctttcagtca ggaatcatta ttcatatcga
      241 gattgaggat gtagaccaga actacaaacg gttgaacgag cttggtataa aggttttaca
      301 cggaccaact gtaaccgatt ggggaacaga gtccttatta gttcaaggac ctgctggtct
      361 agtgcttgat ttttatcgta tgaaataggt cgcgtagtca tttgacgtta accttagcta
      421 tttttaaaat agaaattgag aatatgaact attgaaagat cggagcaatc cggtcttttt
      481 atataaagaa attgcatata atactcatct gctttcaaaa agcattctag tccatctccg
      541 attaacgatg gactttatca cctccttctc caatccttgt atgacatctt ggagttgatt
      601 catgacatct tccaaagttc gaaaggcttt attcttaaat ccacgtttac gaatctcttt
      661 ccacacttgt tcaatggggt tcatctctgg tgtgtatgga ggaataaatg caaagccaat
      721 attagtcgga atctttaagg tacttgattt atgccatata gcattgtcca taacgagtaa
      781 aaaataatca tatggataag cttgtgaaag ctcttctaaa aagacgttca tccactcagt
      841 attacatcca ccagctctta agaaaaatga ttcgcctgta taggcatcaa cagctccata
      901 acaatagcga aattctcgta tatagtgact atggatatgt ggacctactc ctattggaga
      961 ccaacaagat cccagtttac tgattctacc gaaaccagcc tcatcttggt acatcaagcg
     1021 aaccttacga aaacgtctac tggttttaaa tcgctttctt ttcttcttga attgagattt
     1081 tatttttaga cgcgacaatg gtttgagcgt ctgctttctt aggatgttct ggacgtggcg
     1141 taatatttcg ccaaccatgg cgcttcaaca gttgatagaa ggcatcacgt gtgtaggaac
     1201 gacctaactc ctttttataa gcctgaaata aggcatcaat tgtaacaaat tctcctgcct
     1261 ctgtagcctt caaatgacgg gcaagaaagg ctttctcttc ctcaactgtc atatatgcat
     1321 ggttacgacc accacgtgtt tcttgaagga gagagtcgag tccgaactcc tcatattttt
     1381 tacattttgc taaatcgttg tttgattaca gtctaaaagc tctataatct ctttataaga
     1441 tttgcccatc agacgaaata taatagattg aaactagaat agtacacctc tacttctaaa
     1501 acattgttag aaatcgattt gtcctgttct tgtttcattt tactatagaa cgatttgaag
     1561 gcgtttataa tatttagctg tacgagagtc ttttaaaagt gttttgatgg tttggatttc
     1621 ttctttagtt gatttcatat tactattgta taatgctttt tgattttagt ttagtattat
     1681 cgtagaaaat ggactcggtg ctatggatac accggatgag aatggttatg tagcagatga
     1741 ctatcggatt acttacttag aggcccacat caaggccatg cgagatgcca tttaccaaga
     1801 tggggttgac ttgcttggtt atacgacttg gagctgtatc gatccggttt cagctggcac
     1861 aggggaaatg aataagcgct atggctttat ctatgtagat cgagataatg taggaaatgg
     1921 gactctcaaa cgtagcaaga agaagtcctt ctattggtac atgtcattta tagcaatggt
     1981 gtaagcatcg agtagagcac atttgtttac tatttttata aaatcttctc cctgctttat
     2041 aagatgtaaa aaagagttca aatggaactc tttttttgct ataatgaggg gagaaaaatc
     2101 agacaggaga ttaagatgtc agaaccatta tttttacaat cagttatgca agaaaaaatc
     2161 tggggtggta ccaagttacg tgatgagttt ggctacgaca tcccaagtga aaaagtcgga
     2221 gagtactggg ctatctcagc tcatctaaat ggtgtttcta aagttgccaa tggtcgttac
     2281 gagggaacag atcttgctac tttgtatgcg gaacaccgtg aattatttgg caatcgtcca
     2341 gaacctgtat ttccgctttt gaccaagatc ctcgatgcca acgactggct cagtgtccaa
     2401 gttcacccag acgatgctta tggactcgag catgaaggcg aacttggaaa aacagaatgt
     2461 tggtacatca ttgcagcaga tgaaggttca gagattatct acggtcacaa tgccaagtca
     2521 aaagaagaac tccgccagca aatcgaggat aagaactggg atgcgctgtt gacaaaagtg
     2581 ccagttaaag caggagattt cttctatgta ccaagcggta ccatgcacgc tatcggggcg
     2641 ggtatcttga ttcttgaaac ccagcagtct agcgatacca cttaccgtgt ctatgacttt
     2701 gaccgtaagg atgacaaggg caatttacgt gaacttcacc ttgaaaaatc tatcgatgtc
     2761 ttgaacattg gtgaacccgc aaatagccgt ccagtgacaa tcaaagcaga tgatctacgt
     2821 tccactctcc ttgtatccaa tgatttcttc gcagtttaca aatgggaaat tactggaaaa
     2881 gttaactttg aaaagacagc tgactacagc ttgttgagtg tcttggctgg tcaaggtcag
     2941 ctaactgttg acgggaaaaa ttatccaatt caaaaaggca gccactttat cctaccaagt
     3001 gatgttgaag cttggactct ggaagggcaa ggtttggaat tgattgttag ccatccataa
     3061 aaagaaaggg cctgagttca ctactcaagt cctttttgat tacataaatt gggcaatgaa
     3121 gaccacaatg atgatgattg gaatgacgaa acgaagaaac gaagaaggaa gagccagact
     3181 tggaacagtc cttgtttcca tgctctttca tcgagatgga gttcctccat tgcaagagcc
     3241 tttttaaaga tatagcctgt aaaaagtgaa aggtagagag ctccaaatgg catgaggaga
     3301 ttggaaacca agaagtccat agcgtcaaag aaggtcttac caaaaatgtg aacatccgcc
     3361 atgacaccgt aagatagggc tgaaggaatg ccaaagacaa aggtcaaaat tcctaaaata
     3421 acactccatt tggcacgttt gctgttatcc tggttggtga tattgcccac attgatctcc
     3481 agcatcacga cagaagaagt gacagtcgca aagagggagc ggacgtagaa aatggttcca
     3541 aaaggcatct tgtcaaagag ttgaggcaag acgataaaga gcaggctggg tcccccttca
     3601 gactggatat tgaaggggga tcgagcttgg aaaatggcta gacctgccat gatggatatc
     3661 gagatattca tggctacgat ggagattcct gactggacta gattggtttt cttgtccaag
     3721 taagaagcat aggtcaacat gactgtaacc cctagtgaga gggcaaagaa agattgtccc
     3781 agagcataga ggagaccagc gctagtcagt tttgaaaagt ctggtttgag gaagtaaaga
     3841 accccttcca tggcatttgg caaactgaga gagcgactga tgataaaaac aaagacgata
     3901 aagagcaggg gcatcatgac tttcgaagct ctttcaatcc ctttttgaac cccacgtgat
     3961 acaatgaaga tattcaatag gataaaggcc gcttgagctc ctagggcaat ggctggattt
     4021 gaaatgattg aagtaaataa ctgagcataa tcacccgttc caccaagttg gaacaatttc
     4081 ccaaactcaa tacctagata gactagaatc catcctccga taacactgta aaaagataag
     4141 aggataaaga gggcaaaggc gccaatccaa ccgataaagt tgtacttgtt attcttgccc
     4201 agttttccaa aggttttgat agcggaaacg ccagcactac ggccaagggc aaactcagcc
     4261 agcaggagag ggaaaccgat taaaatagtg gaaatgagaa agattagtaa aaagcctcca
     4321 ccgccattag cagcagtcat gtagggaaac ttccaaacgg aaccaagccc gatggccagc
     4381 cagcagatgc tagaataaaa ccaagtttcg acccccattg tgatttttct gacatagtta
     4441 aactctgatc tcctttttca aaataagaaa aagctacttg agttgtcaaa tagccttctg
     4501 tttgattgat agacttgact atcctatcat gttttctaag gtctgtcaag aaaatcattt
     4561 tcaagttttc acacctttct caaaaaagtt aaaaaatttt ctcaaaaacg cttgactctg
     4621 acctaagggg aggggttata ctatcattgt aaggaggaaa tcatgtacca tataaaagaa
     4681 gctgcgcagc tttcaggtgt ctctgtcaag accctgcatc actatgacaa gataggactc
     4741 ttggtcccct taaagtcgga aaacggctat cgaacctaca gtcaagagga tttggaacgc
     4801 cttcaggtca ttctttacta caaatatcta ggcttttctt tagagaaaat agcagagctg
     4861 ttaaaggaag aaaggacaga tttattgccc catttgacta ggcagttgga ctatctaact
     4921 cgcgaaaggc aacatctgga taccttgatt tccaccttgc aaaaaactat tcaagaacaa
     4981 aaaggagaaa gaaaaatgac cattgaggaa aaattcacgg gatttagcta tcaagacaat
     5041 caaaaatacc accaagaagc ggtagagaaa tatggtcaag aagtcatggg acaagcgctc
     5101 gaacgccaaa aaggtcacga agacgaggct acggccgcct ttaaccaagt ctttcaaact
     5161 ttggcacaaa atcttcaagt tggtttacct gcaacagcaa ccgaaaacca ggagcaagca
     5221 gccaagctct tgcaagccat tcgcacttat ggatttgact gctctattga ggtattcggt
     5281 catatcggta aaggttacgt ctataaccca gagtttaagg aaaacattga caagtttggt
     5341 tctggaacag cccagtacac gtcagatgcc attgcagctt acgttcagac aaatgcagaa
     5401 aaaataggct aggaatttcc tagcctattt tttacttcaa atcataaagc cagtcgtcac
     5461 cgtttttgta gtaaaagaat tcactgagat cttcttctag aaacacacga agcatatcag
     5521 acatatcatc ggttgcaagt tttagatgag aaagattttc aaagtcctcc caccaaactt
     5581 tcccttcgtc tgaagactgg agttcaccag taaagtgttc tgtcttgtaa aaaaggacga
     5641 cataacgata atccttgtcg tcataccagt ttttgatacc acagagttgg ggtttggaaa
     5701 tgatcagacc agtttcttct ttcacttcac gaatgacagc atcgacaaag gattcgccac
     5761 gttcaacatg accaccagga aaagtaatgc caggccagtc gggactaact cggtcttgga
     5821 ccaggacctt atctccgttt ttaatcatac acatgttaac aaattcgact gcctctcttc
     5881 tgttcattct tcacaacctt taatctttaa tcataatgca gacttcccgc cacccagccg
     5941 gtacagaggg cagaagtgat gttaaagcca cccgtgtggg cattgatatc cataacttcg
     6001 cctgcaaagt ggaggccagg taccagctta ctttcaaggg ttttaggatt gatttccttg
     6061 agactgactc cacccttggt aacaaaggac tttgcaaggg acatttttcc agttacagga
     6121 attttaagtt ctttaatgga ctgaacaagt tgttctcgtt ccttttcagt cagctgtttg
     6181 actttttcag gatatccttg tacaaaaaat tcggccaagc gttctggtaa caaggttttt
     6241 aaagcgtttt tcaaggattt ttcccgattt tcttctagaa atgtaaccaa gtccttctca
     6301 gaaagttgag gcaaaacatc gagtgagaga acctccccac ctttgacaaa gctagacatg
     6361 cgtagggcag caggacctga caaaccaaag tgggtaaaga gtaaatcatg agtgatgaca
     6421 tgcttaccat aacttagggt cacatcgtcc agagaaatcc cttgtaaggc tttatgtgga
     6481 aaatctgtta ataaaggact ttcagcagcc tcaagctcgg tgatggtatg cttaaaatgg
     6541 cgagcaatct cgtgaccaaa accagtcgaa ccagtcgaag gataagactt accacctgtt
     6601 gtgacaatga gtttctcaca agtgaaggtt tgatccgctg acttaaggac aaactggtca
     6661 tctacttttt taacagaaac gatttctatt tgagtagcaa cttgaccacc tagttcggtg
     6721 attttctttt ccaaagcttc gataatagtc cgagacttgt cactggctgg aaagacgcgt
     6781 ccgtggtctt cgaccttaag tttaacacca ttttctgtaa aaaagttgat gatgtcatga
     6841 ttatcgaact gggagaaaac actgtaaaga aagcgtccgt ttccaggaat tccagctagc
     6901 aggttgtcta agctaccatt gttggtcaca ttgcaacgtc ccccaccagt cccagctaat
     6961 ttttttccaa gtttccgatt tttttcgatg aggagggttt tctgtccata aaagctactg
     7021 gaaatcgtag ccatcatacc agcaggtccc ccaccgatga caatagtatc aaaatgtttc
     7081 atagctctat tgtaccacaa aaaaacaaga gatgatggtc acctcttgtc aagaatgcaa
     7141 ttaatcaatt tcatagccca tcagcaaacc gccatcttct gcatagaaac tgcagagacc
     7201 agaggttggt agaattttaa tatccgcttg tgggaaggtt tcacggattc gctctgagag
     7261 ctgttgacaa catttttcgt tattgcgttg ggccatgaca atacggccac cagcatatcc
     7321 agcttttact aactcatcat aggcagcttg aactgatttc tttgatcccc ttgctttttg
     7381 tagcaattcg agagtcccag tttcactagc ttttccgacc atacgaatgt tgagaaggcc
     7441 aacgaccgta ccgataagct tgctcaaacg gccgttcttc accaagttat cgactttggc
     7501 taggacaaag agcaacttag ttttttcttg ataggcggtg atagcttcaa ccacttcttc
     7561 aaaagacaag ccctggtcaa tcaagtcatt caatttttct acgagtaggt caacttcacc
     7621 accagcagat aaactatcaa tcacatgaat cttagtgtca ggatggtctt ccagataaat
     7681 attctttgct agttgagcac tattgtgact gccagaaagg gtacctgtga tggttactag
     7741 gaaaatgttt ttggcacctt caaatgctcg caaatagtca tctgggcttg gacaagccga
     7801 ttttgaagct tctgcagttg catacatggt ttccatcatt tggtcaatat cgagactggc
     7861 gtcatcaaca aagacctgat cagctacttg aatggttaag gggacactta caaaggttgt
     7921 gttaatagct ggtgttggca gttgacgata atcacaacca gagtcagcaa taattttcca
     7981 agtcatagaa attctccatc tttgtcagtt atacattgac aaaggttctg tcttttttta
     8041 caattatatc atgaaaaccc ttgaaacaaa agcatcatcc gtctgttgtg acaagtagaa
     8101 agaaaatgtt atgtctgaac gtagaatctc tgaaaagtct cttgaaaatc tcagaaaatc
     8161 aaaccaagaa tccaatttat taaccagaga agccattgaa acagccctct tgcaactctt
     8221 ggaaaaaaag gagctgacca agattagtat ttctgaattg gtcaaacgtg caggtgtttc
     8281 gcgtgcggcc ttttatcgca attatgactc caaagaggaa attttagaga gcgtctttaa
     8341 acgaactgtc cacaatatta tggaacagct gcatcattac gatttaaaga cagaccttta
     8401 tttggtttgg gttcaccttt tccgggaggc cagaaaggaa gctagagtga ttcaattggc
     8461 cttggattac catctggaaa aaatctttgt ccaagccatg caggaatttc tagaaaaata
     8521 ccatgggaaa tcaaaaggtg tcagctctta tcttcattcc ttctggagct cagccatcgt
     8581 ctctgtcctt ctaaaatgga tcaaggatgg catgaaggta ccagctgaaa agattgcaga
     8641 tttaggttta ccatttttta aaaaatagag aaaaaggaga aaagagatga ctgaaaaaag
     8701 actggcctgg gatgagtatt ttgcagccca agccctacta attgcgaatc gttccacttg
     8761 taaacgtgct aaagtgggcg cgattctggt aaaagataat aaggttattt ccactggtta
     8821 caatggttcg gtgtcaggga ctgagcattg tattgatcac gaatgtttgg tcattgaagg
     8881 ccactgtgtt cgcacccttc acgctgaggt caatgctatc cttcaaggtg ctgagcgtgg
     8941 tgttcccaaa ggctttacag cctatgtaac ccattttcct tgtctcaact gtacaaaaca
     9001 attgcttcag gtcggctgca agcgcgtggt ttatatcaac cagtaccgaa tggacgacta
     9061 cgcccaatac ctttatcaag aaaaagggac agaattgacc catttaccac ttgagacagt
     9121 acagacagct cttaaagagg ctgatctaat gtaaaaatta tcaaaaataa atggcttaga
     9181 aagattttta aaccgttttt tggtataata agaagaataa attgaaagaa ggaattccaa
     9241 aaatgggaaa aattgaagtt attaatcacc cactgattca acacaaattg tcaatcttgc
     9301 gtcgtacaga tacttctaca aaagcttttc gtgagctagt agatgagatt gcaatgttga
     9361 tggggtatga agtacttcgt gatcttccac tagaagatgt ggaaatcgaa acaccaatta
     9421 caaaaacagt tcaaaaacaa ttggcaggta agaaattggc catcgtccca atcttgcgtg
     9481 caggtatcgg gatggttgat ggtctcttga gcttggttcc agctgctaaa gttggccaca
     9541 tcggtatgta ccgtgatgaa gaaacacttc aaccagttga atacttggtg aaattgcctg
     9601 aggacattga ccaacgtcaa atttttatag tagacccaat gttggcaaca ggtggctcag
     9661 caatcttggc tgttgattct cttaaaaaac gtggcgcatc aaatatcaaa tttgtctgcc
     9721 ttgtatctgc tccagagggt gtaaaagccc ttcaagaagc tcatccagat gtagaaatct
     9781 ttacagcagc cttggatgaa cgtttgaacg aacacggtta tatcgttcca ggtcttggag
     9841 atgctggaga ccgcttgttc ggtacaaaat aagatcgaaa agaagaatga cttggaaaag
     9901 tatttccagt cacgaaagga ggttgggttt ttgtttctgt ctaatgaaag cagagcaaaa
     9961 atttgacctt ttttgaccaa gatattataa tagtcttatc ttcagtcagt tgaccaacaa
    10021 aattaaaact caaaaggaga aatgaatgat tcctgtagtt attgaacaaa caagccgtgg
    10081 agaacgttct tacgatattt actcacgtct tctcaaagac cgcatcatta tgctgacagg
    10141 tccggttgaa gacaatatgg ctaactctgt tattgcccaa ttgcttttct tggatgccca
    10201 agatagtaca aaagatattt acctttatgt caatacacca ggtggttctg tttcagctgg
    10261 tttggcaatc gtagatacca tgaactttat caaggcagat gtccaaacca tcgttatggg
    10321 aatggctgca tctatgggaa cagtcatcgc atcaagtgga gcaaaaggca aacgtttcat
    10381 gcttccaaat gctgaataca tgattcacca accaatgggc ggtacaggtg gtggtaccca
    10441 acaaactgat atggctatcg ctgcagaaca cttgctcaaa actcgtaata ccttggaaaa
    10501 aatcttggct gaaaattcag gtcagtcaat ggaaaaagtc catgcagatg cagaacgtga
    10561 taactggatg agcgcccagg aaacacttga atatggcttt attgatgaaa ttatggccaa
    10621 caattcattg aactaatgat gatagaaggc aaactcgact gggtttgctt tttttggtat
    10681 aatagggaga gatttcttag aaagaggatt tatcatgttt gaaaaagtca atcgctctgg
    10741 cttgattatc tatctttact ataatcgtga tgccaaaaaa ttgcaggatt atggagatat
    10801 tacctatcat tccaagaaac atcgttactt acaactctat gttccaactc aagaagtgga
    10861 gcaattggtc ggacgcttga gcaaggaaaa atttattaaa aaagttaggg tttgtcatat
    10921 ccaagagttg gaaacaccct ttgtgggcaa tctttatcga taggaaaacg ttatcataga
    10981 aaaagttcaa ggaaaacatt gacaattttc tgataattcg gtatattctt aacagactat
    11041 ttaagaaata aggagacaaa aagatgaaga aaaaatttgc cctatcgttt gtggcgcttg
    11101 caagtgtagc acttcttgca gcctgtggag aagtgaagtc tggagcagtc aacactgctg
    11161 gtaactcagt agaggaaaag acaattaaaa tcgggtttaa ctttgaagaa tcaggttctt
    11221 tagctgcata cggaacagct gaacaaaaag gtgcccaatt ggctgttgat gaaatcaatg
    11281 ccgcaggtgg tatcgatgga aaacaaatcg aagtaatcga taaagataat aagtctgaaa
    11341 cagctgaggc tgcttcagtt acaactaacc ttgtaaccca atctaaagta tcagcagtcg
    11401 taggacctgc gacatctggt gcgactgcag ctgcggtagc gaacgctaca aaagcaggtg
    11461 ttccattgat ctcaccaagt gcgactcaag atggattgac taaaggtcaa gattacctct
    11521 ttattggaac tttccaagat agcttccaag gaaaaattat ctcaaactat gtttctgaaa
    11581 aattaaatgc taagaaagtt gttctttaca ctgacaatgc cagtgactat gctaaaggga
    11641 ttgccaaatc tttccgcgag tcatacaagg gtgaaatcgt tgcagatgaa actttcgtag
    11701 caggtgacac agacttccaa gcagccctta caaaaatgaa agggagagac tttgatgcta
    11761 tcgttgttcc tggttactat aatgaggctg gtaagattgt aaaccaagcg cgtggcatgg
    11821 gaattgacaa accaatcgtt ggtggtgatg gattcaacgg tgaggagttt gtacaacaag
    11881 caactgctga aaaagcatca aacatctact ttatctcagg cttctcaact actgtagaag
    11941 tttcagctaa agctaaagcc ttccttgacg cttaccgtgc taagtacaat gaagagcctt
    12001 caacatttgc agccttggct tatgattcag ttcaccttgt agcaaacgca gcaaaaggtg
    12061 ctaaaaattc aggtgaaatc aagaataacc ttgctaaaac aaaagatttt gaaggtgtaa
    12121 ctggtcaaac aagcttcgat gcagaccaca acacagtcaa aactgcttac atgatgacca
    12181 tgaacaatgg taaagttgaa gcagcagaag ttgtaaaacc ataatagaaa aatgttgaaa
    12241 tagggaatga gcctttgact cactccctgt ttcgatattt aatactcttc gaaaatctct
    12301 tcaaactgcg tcaacgtcgc cttggattat atatgtgact gacttcgtca gtcttatcta
    12361 caacctcaaa gcagtgcttt gagcaacctg cggctagttt cctagtttgc tctttgattt
    12421 tcattgagta taagaaccta tcaaaaagtg agggaaaacc ctcggaatta taaatagaaa
    12481 gagtgaatct tatgctccaa caactcgtaa atggtttgat tctaggtagt gtttacgcgc
    12541 tgttagccct aggatatacc atggtttacg gaattatcaa gctcatcaac ttcgcccatg
    12601 gtgatattta tatgatggga gcctttatcg gttatttctt gatcaattct ttccaaatga
    12661 atttctttgt agcgcttatt gtagctatgc tagcgacagc tattcttggt gtcgtgattg
    12721 agtttcttgc ttaccgacct ttgcgccact ctactcgtat tgctgttttg attacggcta
    12781 ttggggtttc tttcctattg gagtatggaa tggtctatct ggttggtgcc aatacccgtg
    12841 ccttccctca agcgattcaa acagttcgat atgatttggg agcaattagc ttaacaaatg
    12901 tgcagttaat gattttggcc atttccttga ttttgatgat tttgttacaa gtcattgtcc
    12961 aaaagactaa gatggggaaa gccatgcgtg cagtatcagt agatagcgac gcggcacaat
    13021 tgatggggat caatgtaaac cgtacgatta gctttacctt cgctttgggt tctgctcttg
    13081 cgggtgcggc tggtgttctg attgctcttt attataactc tcttgagcct ttgatggggg
    13141 ttactccagg tcttaaatct ttcgttgccg cagtacttgg tggtatcgga attattcccg
    13201 gtgcggctct tggtggcttt gtgattggtc tattggaaac ctttgcgaca gcctttgaga
    13261 tgtcagattt ccgtgatgcc attgtttatg gaatcttgtt gttgatcttg attgtccgcc
    13321 cagctggtat ccttggtaag aatgtgaaag agaaggtgta aacgatgaag gaaaatttaa
    13381 aagttaatat tctatggtta ctccttttgt tagctggcta tagcttgatt agtgtactgg
    13441 tttcagtcgg agtacttaat ctattctatg tacagatttt acaacaaatt ggaattaata
    13501 ttattttggc tgttggtctc aacttaatcg ttggtttttc aggacaattt tcacttggtc
    13561 atgctggttt catggcgatt ggtgcctatg cagcagctat tattggttct aaatcaccaa
    13621 cctacggtgc cttctttgga gctatgcttg taggggcttt gctttcagga gcagttgcct
    13681 tacttgtcgg cattccaacc ttgcgcttga agggggacta tcttgcggta gcaactctgg
    13741 gtgtttctga aattatccgt atctttatca tcaatggtgg aagtcttaca aatggtgcgg
    13801 caggtatctt agggattcct aactttacaa cttggcaaat ggtttacttc tttgtcgtga
    13861 ttacaaccat tgcaaccttg aacttcttgc gtagcccaat tggccgttca accctctctg
    13921 ttcgtgaaga tgaaatcgct gctgagtcag ttggggttaa tacgactaaa attaaaatca
    13981 tcgcttttgt ctttggtgcc attactgcaa gtattgctgg gtcacttcag gcaggattta
    14041 tcgggtctgt tgtaccgaaa gattacacct tcatcaactc aatcaacgtt ttgattattg
    14101 ttgtatttgg tggactcggt tccattacag gtgcgattgt ttcggctatt gttctgggaa
    14161 ttttgaatat gcttctccaa gatgttgcta gtgtgcgtat gattatttac gctttggcct
    14221 tggtattggt aatgattttc agaccaggtg gactccttgg aacgtgggaa ctgagcctat
    14281 cacgtttctt taaaaaatct aagaaggagg aacaaaacta atggcattac ttgaagtaaa
    14341 acagttaacc aaacattttg gtggtctaac agctgttgga gatgtgactc ttgaattgaa
    14401 cgaaggggaa ctggttggat taatcggtcc aaacggagct gggaaaacca cccttttcaa
    14461 ccttttgacc ggtgtttatg aaccaagcga gggaacagta accctagatg gtcacctttt
    14521 gaatgggaaa tcaccttata agattgcctc tttgggactt ggacgtactt tccaaaatat
    14581 ccgtctcttt aaagatttaa cagttttaga taatgttttg attgcttttg gaaaccatca
    14641 caaacagcat gtttttacta gtttcttacg cttaccagct ttttacaaga gtgaaaaaga
    14701 attaaaggat aaagctttgg aattgttgaa aatctttgat ttagatggtg atgcagagac
    14761 tcttgctaaa aatctttcct acggacaaca acgtcgtttg gaaattgttc gtgcccttgc
    14821 tacggaacct aaaattctct tcttagatga accagcagca ggtatgaacc cacaggaaac
    14881 agccgaattg actgagttaa ttcgtcgtat caaagatgaa tttaagatta caatcatgtt
    14941 gattgaacac gatatgaatc tggtcatgga agtaacagaa cgtatctacg tacttgaata
    15001 tggccgttta attgctcaag gaactccaga cgaaattaag accaataaac gcgttatcga
    15061 agcttatcta ggaggtgaag cctaatgtct atgttaaaag ttgaaaatct ttctgtgcat
    15121 tacggtatga tccaagcagt ccgtgatgta agctttgaag ttaatgaagg agaagttgtt
    15181 tcccttatcg gtgccaacgg tgcaggtaag acaactattc ttcgcacctt gtcaggtttg
    15241 gttcgaccaa gttcaggaaa gattgaattt ttaggtcaag aaatccaaaa aatgccagct
    15301 cagaaaatcg tggcaggtgg tctttcacaa gttccagaag gacgccacgt ctttcctggc
    15361 ttgactgtta tggaaaatct tgaaatggga gctttcttaa agaaaaatcg tgaagaaaat
    15421 caagctaact tgaagaaggt tttctcacgc tttcctcgtc ttgaagaacg gaagaaccaa
    15481 gatgcagcta ctctttcagg aggggaacaa caaatgcttg ccatgggacg cgctcttatg
    15541 tcaacaccaa aacttcttct tttagatgaa ccatcaatgg gacttgcccc aatcttcatc
    15601 caagagattt ttgatatcat tcaagatatt cagaagcaag gaacaaccgt cctcttgatt
    15661 gaacaaaatg ccaataaagc acttgcaatc tctgaccgag gatatgtatt ggaaacagga
    15721 aaaatcgtcc tatcaggaac aggaaaagaa ctcgcttcat cagaagaagt cagaaaagca
    15781 tatctaggtg gctaaaacaa tccagtggat tgttttagtc ggcagatgaa gattacgaag
    15841 taatcatcaa tatagtccgg gggccctttt tagtcggtgg atgaagattg cgaagcaatc
    15901 atcaaatcca gaggattgtt ttagccggta gattgagatt gcaaacaaat ctgcatctac
    15961 attgaaagct gaatttctaa taattgaaaa aatcgaatga aacgtatctt accttcattc
    16021 agggagctcg attttagagc tctttttgct agcttattca tacttttttg aatttcgaaa
    16081 aagaaatgta agcgtttgat agatttacaa aaagattgta taatggggat aagaatagaa
    16141 aaggagaagt ctcatggcag ttaaagattt tatgacccgc aaggtagttt atattagtcc
    16201 agatacaaca gtatctcatg cagcagattt gatgagagag caagaattgc accgcttgcc
    16261 tgttatcgaa aatgatcaat tggttggttt ggtgactgag ggaaccattg cacaagcaag
    16321 tccatctaaa gcaacaagtc tttctatcta tgagatgaat tatcttctga ataagacaaa
    16381 agtaaaagat gtcatgattc gcgatgttgt cactgtctca ggctatgcta gtctagaaga
    16441 tgcaacttat ctgatgttga aaaataagat tggtattctc cctgtcgtag ataaccatca
    16501 agtatacgga gttattactg accgtgacgt tttccaagcc tttcttgaaa ttgcaggtta
    16561 tggcgaagaa gggattcgtg tacgctttgt tacagaagat gaagttggtg ttcttggaaa
    16621 aattgtttct ttgattgtag aagaaaattt gaatatctcc catacagtca atattccgcg
    16681 taaggatggt aaggtcatta tcgaagtgca aatcgatgga tcaattgatt taccagcctt
    16741 gaaagaaaaa tttgaagcaa atggtattca agtggaagaa atcgctcgca cttcagcaaa
    16801 agtcttgtaa gaagggaagc ccaaaggctt cttttttcat gaaaagggga ttagagaaaa
    16861 agatggaaag aaatgataaa atatgctata atgaaataat gtaaaaaagg agtatttatg
    16921 gacatttcag taattcgtca gaaaattgac gcaaatcgtg aaaaattagc ttctttcagg
    16981 gggtctcttt gacctcgaag ggctagagga agagattgcc atcttggaaa acaagatgac
    17041 agaacctgat ttttggaacg ataatattgc ggcccaaaaa acgtcgcaag aattaaatga
    17101 attaaaaaac acttacaata ccttccataa gatggaagag ttgcaggatg aagtcgaaat
    17161 tttattggat tttttggctg aagacgagtc agtgcatgat gaactggtag cgcagttagc
    17221 cgaacttgat aagataatga ccagctacga gatgactcta ctcttgtcag aaccttatga
    17281 ccacaacaat gccatcttgg aaatccatcc aggttctggt ggtactgagg cgcaggactg
    17341 gggtgatatg ttgcttcgta tgtatactcg ttatggtaat gctaaaggct ttaaagtgga
    17401 agtgttggat taccaagcag gtgatgaggc tggtattaag tcggtaactt tatcatttga
    17461 agggcctaat gcctatggtc tcctcaagtc agaaatgggt gttcaccgct tagtgcgaat
    17521 ctcaccattt gactctgcca aacgtcgcca tacctctttc acatctgtag aagtgatgcc
    17581 agaattggat gatactattg aagtggaaat ccgtgaagat gatatcaaga tggatacctt
    17641 ccgttcaggt ggtgccggtg gacaaaacgt caataaggtt tcaacaggtg tacgtttaac
    17701 ccacattcca actggaattg ttgtccaatc aacagtggat cgtacccagt atggaaatag
    17761 agatcgtgcc atgaagatgt tgcaggctaa gctctatcaa atggagcaag ataagaaggc
    17821 tgcggaggta gattctctca aaggtgagaa aaaggagatc acttggggaa gccaaatccg
    17881 ttcttatgtc ttcacgcctt atactatggt aaaagatcac cgaactagct ttgaggttgc
    17941 tcaggtagat aaggttatgg atggggacct agatggtttt atcgatgctt atctcaagtg
    18001 gcgaattagc taagatagaa aggaactcac atgtcaatta ttgaaatgag agatgtcgtt
    18061 aaaaaatacg acaacggaac aactgctcta cgcggtgttt cggttagcgt tcaaccgggg
    18121 gaatttgctt acatcgtagg accttcagga gcagggaagt caacttttat tcgttctctg
    18181 tatcgtgaag taaaaatcga taaaggaagc ctatcagttg ctggttttaa tctggttaag
    18241 atcaaaaaga aagatgtccc gcttctacgt cgtagtgttg gggttgtctt ccaggattat
    18301 aaactgttac caaagaaaac tgtctatgaa aatattgctt acgctatgga agtaatcggg
    18361 gaaaatcgcc gtaatatcaa aagacgagtg atggaagttt tggacttggt tggattgaag
    18421 cataaggttc gttcttttcc aaatgaactc tcaggtgggg agcaacagcg aattgcgatt
    18481 gcgcgtgcaa ttgtaaataa tcccaaagta ttgatagctg atgagccaac aggaaatctg
    18541 gatccggata attcatggga aattatgaat ctcttggaac ggattaacct acaaggaaca
    18601 actattttga tggcgactca taatagccag attgtaaata ccttgcgcca ccgtgtcatt
    18661 gccattgaaa atggccgtgt cgttcgtgac gaatcaaaag gagagtatgg atacgatgat
    18721 tagtagattt tttcgccatt tatttgaagc cttaaaaagt ttgaaacgaa atggttggat
    18781 gacagtagct gctgtcagtt cagtcatgat tactttgacc ttggtggcaa tatttgcatc
    18841 tgttattttc aatacagcga aactagctac agatattgaa aataatgtcc gtgtagtagt
    18901 ttatatccga aaggatgtgg aagataatag tcagacaatt gaaaaagaag gtcaaactgt
    18961 tacaaataat gactactaca aggtatatga ttctttgaag aacatgtcta cggttaaaag
    19021 tgttaccttt tcaagtaaag aagaacaata tgaaaaatta accgagataa tgggagataa
    19081 ctggaaaatc tttgaaggag atgccaatcc tctctatgat gcctatattg tagaggcaaa
    19141 cactccaaat gatgtaaaaa ctatagccga agatgctaaa aaaattgaag gtgtctctga
    19201 ggttcaagat ggcggtgcca atacagaaag actcttcaag ttagcttcat ttatccgtgt
    19261 ttggggacta gggattgctg ctttgttaat ttttatcgca gtttttttga tttcaaatac
    19321 cattcgtatt accattattt cccgcagtcg cgaaattcaa atcatgcgct tggtcggagc
    19381 taaaaacagt tatatccgtg gaccgttctt gttagaagga gcctttatcg gtttattggg
    19441 agctatcgca ccatctgttt tggtctttat tgtttatcaa attgtttatc aatctgtcaa
    19501 caaatcgttg gtagggcaaa atctatccat gattagtcca gatttattta gtccgttgat
    19561 gattgcccta ctatttgtga ttggggtttt cattggttca ttgggatcag gaatatccat
    19621 gcgccgattc ttgaagattt aggtaaaata gctgctttta tgaggagatt gtaaaatctc
    19681 cttttttgct acaagagttt ttgaaaagag atgcgcagaa gaaaagagct tccaaagaag
    19741 tcccccagag aagacttctt gatggctaat ttgaacttga aatttgactc actagaaatt
    19801 ttttagaaaa aagtgtaatt tttttataaa agcctttaca aaaaaaatta aagtggtata
    19861 attaaattat agaaggtgca aacgttttcg taaaacgttt gcctaaataa aaataaagga
    19921 gatttgaatg atgaaagata cattcaaaaa tgtcttgtct ttcgaatttt ggcaaaaatt
    19981 cggtaaggct ttgatggtag ttatcgcggt tatgccggct gctggtttga tgatttcaat
    20041 cggtaagtct atcgtgatga ttaacccaac ctttacacca cttgtcatca caggtggaat
    20101 tcttgagcaa atcggttggg gggttatcgg taaccttcac attttgtttg ccctagccat
    20161 tggaggaagc tgggctaaag aacgtgctgg tggtgctttc gccgctggtc ttgccttcat
    20221 tttgattaac cgtatcactg gtacaatttt tggtgtatca ggcgatatgt tgaaaaatcc
    20281 agatgctatg gtaactactt tctttggtgg ttcaatcaaa gttgctgatt actttatcag
    20341 tgttcttgaa gctccagcct tgaacatggg ggtattcgta gggattatct caggttttgt
    20401 aggggcaact gcttacaaca aatactacaa cttccgtaaa cttcctgatg cactttcatt
    20461 cttcaacggg aaacgtttcg taccatttgt agttattctt cgttcagcaa tcgctgcaat
    20521 tctacttgct gctttctggc cagtagttca aacaggtatc aataacttcg gtatctggat
    20581 tgccaactca caagaaactg ctccaattct tgcaccattc ttgtatggta ctttggaacg
    20641 tttgctcttg ccatttggtc ttcaccacat gttgactatc ccaatgaact acacagctct
    20701 tggtggtact tatgacattt taactggtgc agctaaaggt actcaagtat tcggtcaaga
    20761 cccactatgg cttgcatggg taacagacct tgtaaacctt aaaggtactg atgctagtca
    20821 atatcaacac ttgttagata cagtacatcc agctcgtttc aaagttggac aaatgatcgg
    20881 ttcattcggt atcttgatgg gtgtgattgt tgctatctac cgtaatgttg atgctgacaa
    20941 gaaacataaa tacaaaggta tgatgattgc aacagctctt gcaacattct tgacaggggt
    21001 tactgaacca atcgaataca tgttcatgtt catcgcaaca cctatgtatc ttgtttactc
    21061 acttgttcaa ggtgctgcct tcgctatggc tgacgtcgta aacctacgta tgcactcatt
    21121 cggttcaatc gagttcttga ctcgtacacc tattgcaatc agtgctggta ttggtatgga
    21181 tatcgttaac ttcgtttggg taactgttct ctttgctgta atcatgtact ttatcgcaaa
    21241 cttcatgatt caaaaattca actacgcaac tccagggcgc aacggaaact acgaaactgc
    21301 tgaaggttca gaagaaacca gcagcgaagt gaaagttgca gcaggctctc aagctgtaaa
    21361 cattatcaac cttcttggtg gacgtgtaaa catcgttgat gttgatgcat gtatgactcg
    21421 tcttcgtgta actgttaaag atgcagataa agtaggaaat gcagagcaat ggaaagcaga
    21481 aggagctatg ggtcttgtga tgaaaggaca aggggttcaa gctatctacg gtccaaaagc
    21541 tgacattttg aaatctgata tccaagatat ccttgattca ggtgaaatca ttcctgaaac
    21601 tcttccaagc caaatgactg aagcacaaca aaacactgtt cacttcaaag atcttactga
    21661 ggaagtttac tcagtagcag acggtcaagt tgttggtttg gaacaagtaa aggatccagt
    21721 atttgctcaa aaaatgatgg gtgatggatt tgcagtagaa cctgcaaatg gaaacattgt
    21781 atctccagtt tcaggtactg tgtcaagcat cttcccaaca aaacatgctt ttggtattgt
    21841 gacggaagca ggtcttgaag tattggttca cattggtttg gacacagtaa gtcttgaagg
    21901 taaaccattt acagttcatg ttgctgaagg acaaaaagtt gcagcaggag atctccttgt
    21961 cacagctgac ttggatgcta tccgtgcagc aggacgtgaa acttcaacag tagttgtctt
    22021 cacaaatggt gatgcaatta aatcagttaa attagaaaaa acaggttctc ttgcagctaa
    22081 aacagcagtt gctaaagtag aattgtaata tacttgaggt tggaagctgt attccaacct
    22141 cttattttgg gagaaaagaa tgaaattttt aacactcaat actcacagtt ggatggagaa
    22201 agaagcagag gaaaaattcc agattttgct tgaagatatt cttgaaaagg actatgattt
    22261 gatttgtttc caagaaatca atcaggagat gacctcgtca gaggtggagg ttaatgacct
    22321 ttatcaagct ttgccagcag ctgagcctat tcaccaagac cattatgtta gactcttggt
    22381 tgaaaagttg ttagagcaag ggaaaaatta ctactggacc tgggcttata accatatcgg
    22441 ctataaccgc taccacgaag gtgtggctat cttgtctaaa acacctattg aagccagaga
    22501 aattttggtt tcagatgtgg atgatccaac agactatcat actcgccgtg ttgccctagc
    22561 tgaaactgta gtcgatggca aggagctagc agttgccagt gttcatctct cttggtggga
    22621 taaaggtttc caagaagaat gggcacgatt tgaggctgtc ttgaaaaaat tgaacaagcc
    22681 acttttacta gctggagatt ttaacaaccc agcaggtcag gaaggttacc aagctatttt
    22741 agctagtcca ttaggcttac aagacgcatt tgaagttgct caagagaaaa gtggtagcta
    22801 tactgttccg cctgaaattg atggctggaa agggaacact gaaccccttc gaatcgatta
    22861 tgtctttact accaaagagt tagcggtgga aaatttacat gtcgtatttg atggtaacaa
    22921 gagtccacaa gtgagtgatc actatggctt gaatgctatg ttaaactgga aataataact
    22981 gaaaagaggt tggaactata aaattccagc cttttcttac tagagaagct actggaaata
    23041 gcctaaataa gtgagactac tgtaatggaa taaaatatgg tataattgat aagatagata
    23101 gaatcgagga tgttatgtca tttacgaaat ttcaatttaa aaactatatt agagaagcct
    23161 tggaggagtt aaaatttaca actccaacag aggtgcaaga caagttgatt cctattgttt
    23221 tggcaggtcg tgacctagta ggagaatcaa aaacaggttc aggtaagact catactttct
    23281 tgttaccgat tttccagcaa ttagatgaag ctagcgatag tgtacaagca gtgattactg
    23341 caccgagtcg tgagttggct actcaaattt accaagtagc gcgtcagatt tcagctcact
    23401 cagatgtcga agttcgtgtg gttaattatg tgggtggtac ggataaggct cgccagattg
    23461 agaaattgga aagcaatcag cctcatattg ttattggaac accaggccgt atctacgact
    23521 tggttaaatc tggtgattta gctattcata aagccaagac atttgttgtt gatgaagcag
    23581 atatgacctt ggatatggga ttcttggaaa ttgttgataa gattgctggc agtcttccaa
    23641 aagacttgca attcatggtc ttctcagcga ctatcccaca aaaactgcaa ccattcttga
    23701 aaaaatactt atcaaatcct gttatggaga aaattaagac taaaacggtt atttctgaca
    23761 ccattgataa ttggttgatt tcgaccaagg gacatgatag gaatgctcaa atttaccaat
    23821 tgactcagtt gatgcagccg tatttggcaa tgatttttgt taacactaaa acgcgtgctg
    23881 atgaattgca ttcatatctg actgctcaag gcttgaaggt tgcaaaaatc catggagata
    23941 ttgcccctcg tgaacgcaag cgaatcatga atcaggtgca aaatctggat tttgagtata
    24001 ttgtcgcaac agatttagca gcgcgtggga ttgacattga aggtgtcagc catgtcatca
    24061 atgatgccat tccgcaagac ttatcttttt ttgttcaccg tgttggtcgt actggacgaa
    24121 atggcctacc aggtacagct attacccttt atcagccaag tgatgactcg gatatccgtg
    24181 agttggagaa attgggaatc aagtttagtc ctaagatggt caaagatggg gaatttcaag
    24241 atacctatga ccgtgatcgt cgtgccaacc gtgagaaaaa acaagataaa cttgatatcg
    24301 aaatgattgg tttggttaaa aagaaaaaga aaaaagtcaa accgggttat aagaagaaaa
    24361 ttcaatgggc ggttgatgaa aagcgccgta aaactaagcg tgctgaaaat cgcgctcgcg
    24421 gtcgtgcaga gcgtaaagct aaacgccaaa cattttaata gaaattgttg gagtactgag
    24481 ctccaacttt tttatttatg agaacgaact atctaaaccg aaacactaca ttaaagactg
    24541 caaattgcga ttaaaaatgg tataatgata aagttatata gtcccgataa gatggtaggt
    24601 atttattacg aagagttttc ctatcagtag tttgcaattc gcaaagaatg acggcttcga
    24661 ggttgctcgt ctttctacgg ttgccgccat actgcggtca ccctatgcgc cttactagct
    24721 tcagaaataa aaaagtatcg tttttatttc tgaagctagt aactcttaga taatggaaat
    24781 tcctatcagt actttgtaac tctataacaa tattttttaa ggggggacat ttttatgtca
    24841 gaacgtaaat tattcacgtc tgaatctgta tctgaggggc atccggataa gattgcagac
    24901 caaatttcag atgcgatttt ggatgctatt ttagcaaagg atccagaggc gcacgttgct
    24961 gctgaaacag ctgtatatac tggttctgtc cacgtttttg gtgaaatttc tacaaatgcc
    25021 tatgtggata ttaaccgtgt ggttcgtgat accattgcag agattggtta taccaataca
    25081 gaatatggat tttctgctga gacggtggga gtacacccat ctttggtgga acaatctcct
    25141 gacatcgctc aaggtgttaa cgaagccttg gaggttcgtg gaaatgctga tcaagatcca
    25201 ctggacttga ttggagcagg tgaccaaggg ctcatgtttg gatttgcagt agatgaaaca
    25261 gaagagctca tgccattgcc aattgcactc agtcataaat tggttcgtcg tctggcagaa
    25321 cttcgtaagt ctggagaaat tagctatctc cgtccagatg caaaatcaca agttacagtt
    25381 gagtacgatg aaaatgaccg tccggtacgt gtagatacag tcgttatttc tactcagcat
    25441 gatccagagg ccactaatga acaaatccat caagatgtga ttaacaaggt catcaaagaa
    25501 gttattccat cttcttatct tgatgataag acaaaattct ttatcaatcc gacaggtcgt
    25561 tttgtaatcg gtggtcctca aggggactca ggtttgactg gtcgtaagat tattgtagat
    25621 acttatggtg gctactctcg tcatggtggt ggtgccttct ctggtaaaga tgcgactaag
    25681 gtggatcgtt cagcctctta tgcggctcgc tatattgcca agaatatcgt tgcagcaggc
    25741 cttgctaaga aggcagaagt gcagttggcc tatgctatcg gtgttgcgca acctgtttct
    25801 gttcgtatcg atactttcgg tacaggaaca gtagctgaaa gtcaacttga aaaagcggct
    25861 cgtcaaatct ttgaccttcg ccctgcaggg attatccaaa tgctggacct caagcgtcca
    25921 atttaccgtc aaacatcggc ttacggtcac atgggacgta cagatattga tcttccatgg
    25981 gaacgtttgg ataaggtaga tgctttgaaa gaagcagtaa aataagattt taagagggga
    26041 acgtcctctc ttttttatag tttttaacta tactgggata ctgttctgaa aatccatttt
    26101 gcgaaagtag agatttacat gtatagtaga ttgaaactag aatagtacac ctcaacttct
    26161 aaaacattgt tagaaatcga tttgactgtc ctgatcgatt tctcctgttc ttgtttcatt
    26221 ttactatatt tctttaaaaa tgataaaggt tgagatttct cctcgtaata gataatcatg
    26281 gggatatttc aatccaaagt tttattcgtt atcacttgac tattgcaagg ttttctagag
    26341 caacagagtc atggaatgga ctcatggttg agatttctcc ttgttgcttg gacttcattc
    26401 aaaagtctgt tacccaagcc ttgttcaaac ttccaataca ctagctgttt ccatagcatg
    26461 acttctgtac tagactttct tttccgaata aatagataga accacagaat ctagtaaacc
    26521 tagaattaaa attatggtat aatattagca ataaaagaaa tctggaggat tagaatcatg
    26581 gtatcaacga aaacacaaat tgctggtttt gagtttgaca attgcttgat gaatgcagca
    26641 ggtgtggctt gtatgacgat agaggagtta gaagaggtca aaaactcagc ggcaggaacc
    26701 tttgttacta agacagcgac cttggacttc cgtcagggga atcctgagcc acgctaccaa
    26761 gatgttccac ttggttccat caactctatg ggcttgccaa ataatggctt agactattat
    26821 ttggattatc ttttagattt gcaggaaaaa gagtcgaacc gaactttctt cttatctctg
    26881 gtcggcatgt ctccagagga aacccatact attttgaaaa aagtccaaga gagtgatttt
    26941 cgtggtctga ctgagctaaa tctttcctgt ccaaatgttc caggtaaacc tcagattgcc
    27001 tatgattttg agacaacaga ccggattttg gcagaagtgt ttgcttactt caccaaacct
    27061 cttggaatta aattgccacc ttattttgat attgttcact ttgaccaagc ggcagctatt
    27121 ttcaacaaat atccgctcaa gtttgtcaac tgcgttaact ctatcggaaa cggcctctat
    27181 atagaagacg aatctgtcgt tattcggcct aagaatggtt ttggtggaat tggtggagaa
    27241 tacatcaaac cgactgctct agccaatgtt cacgcctttt atcaacgttt aaatcctcaa
    27301 atccaaatta tcggaacagg tggcgttctg actggtcgag atgcctttga acacatcctc
    27361 tgtggagcaa gtatggtgca ggtgggaacg acccttcaca aagaaggcgt cagtgctttt
    27421 gaccgcatta ccaatgaact gaaagcaatc atggtggaaa aaggctacga gagcttagaa
    27481 gatttccgtg ggaaattgcg ctatattgac taaattaaat cgaaaaatca gaagaaagaa
    27541 gggacgatgc tagccattga agaaagtcag aagttgactt tatcaaattt accgagcctg
    27601 agcctattta cagggacaga tcagggtcag tttgaagtga tgaagagtca aatgttgaaa
    27661 cagattgggt atgattctgc tgacctcaac tttgcctact ttgatatgaa agaagtagtt
    27721 tacaaggatg tggaactgga gttggtcagc cttcctttct ttgcggatga gaaaatcgtg
    27781 atattagatt attttatgga tatcacgact gctaagaaac gctttttgac agatgatgag
    27841 cttaagtcat ttgaggaata ccttgacaat ccttctccaa caaccaagtt gataatcttt
    27901 gcagaaggaa agctggatag caaaagacgg ttagtcaaat tacttaagcg tgatgccaag
    27961 gtcttcgatg cagtagaagt aaaagaacaa gaattgcgcc agtatttcca aaagtggagt
    28021 cagaaacaag gtctgcagtt taccaatcat tcttttgaaa atctcctcat caagtcgggg
    28081 tttcaattta gcgaaatcca gaaaaatctt ctctttttac agtcctataa ggcgaattct
    28141 gttatcgagg aagaggatat tgttaacgca attcccaaga ccttgcagga caatattttt
    28201 gatttaactc agtttattct gactaaaaag atggatcagg cgcgcgattt agtgagagac
    28261 ttgaccttgc aaggggaaga tgaaatcaaa ctgattgcag tcatgctggg acaatttcgg
    28321 acttttactc aggtgaagat tttggcggag tctggccaaa cagaatcgca gattgcaagt
    28381 agtttaggta gttatctggg acgtaaccca aatccttatc aaatcaagtt tgcattaaga
    28441 gattcgagag gactttcttt gagctttctg aagcaagcta tttcctattt gattgagaca
    28501 gactatcaga ttaagacagg tctttatgaa aaaggtttcc tttttgaaaa ggcactctta
    28561 cagattgcta gtcaggtcaa ttgacatttg ttgaaactac aacccgcgtc aggattatct
    28621 tgtcgtgggt ttcttgctga tttgcttatt ttattagaaa gtatatcagt gatttcctta
    28681 tctataagca aaaaacttga aaaaagtgaa tgtttgcgtt atcattttca tatagaaaga
    28741 aaaagaggta ttacagatgg ctattatctt accagaactt ccatatgcat acgacgcttt
    28801 ggaaccatac atcgatgcgg aaacaatgca tttgcaccat gacaaacacc atcaaactta
    28861 tgtcaacaat gccaatgcag ctttagaaaa acaccctgaa atcggtgaag accttgaagc
    28921 cttgcttgct gatgtagaat ctatcccagc tgatatccgt caagcactta tcaacaatgg
    28981 tggcggacac ttgaaccacg ctcttttctg ggaattgatg actcccgaga aaacagctcc
    29041 ttcagcagaa ctggcagcag caatcgatgc aacatttggt tcatttgaag aattccaagc
    29101 agccttcact gcagcagcaa caactcgttt tggttcaggt tgggcatggt tggttgtcaa
    29161 caaagaaggg aaacttgaag tgacttcaac agcaaaccaa gacacaccaa tctcagaagg
    29221 taaaaaacca atcttgggct tggacgtttg ggaacatgct tactacgtga aataccgcaa
    29281 cgtgcgtcct gactacatca aagctttctt ttcagtaatc aactggaata aagtagatga
    29341 attgtacgca gctgctaaat aatgatagtt ggagggaaga attgttcttc tcttttttag
    29401 gttataagat tctggtctga caaaatcgtc agactttttt catttttatg agaaacgtgc
    29461 taactgctag aaattatggt agaataaagt attaagtaat cgtggaaaaa ggatatctat
    29521 gcgaaaagaa attgcacctg aattatacaa ttataacaag tttcctggtc cggagttcca
    29581 tttacacggg gacaaggtcg aaacggaagg gatagctttt tccttggttg aaaatatcaa
    29641 ggatgccttt gatgtgacga cttttaatca gcgtttttca gaagtcttaa ccaagtttga
    29701 ttatatcgtg ggggactgga gcaacgaaca gcttcgccta cgaggttttt acaaggatga
    29761 ccgaacagaa gaaaaacttg aaaaaatcag tcgtttacaa gactaccttt tagagtattg
    29821 tagttatggt tgtgcctatt ttgtcttaga aaatgaagcc cctaagcgag catcatttga
    29881 caagaaaatg cgtaagacgg aagaagaaac accttctaga aaaggaaaga aaccgactca
    29941 aactaaacga aagtcgaatg cagataagaa aaatagacgt cgtcagaaag accagcattc
    30001 tcagaaagag gacaagggac aacgtcattt tgtcattcgt cagaagtgag tagagaataa
    30061 ggagaagaaa tgaaaccctc aattcatagt ttggtacatc aaaccatgca ggaatgggta
    30121 ttggagcagg gagaaaagaa attccgtgca gatcaaatct gggaatggct ctaccgtaaa
    30181 cgtgtgcagt catttgaaga aatgaccaac ctttccaagg atttgattgc taagctcaat
    30241 gaccagtttg tggtcaatcc cttgaaacaa cgtattgtgc aagagtctgc tgatggtaca
    30301 gtcaaatatc tctttgaatt gcccgacggt atgttaattg agactgtact catgcgtcaa
    30361 cactatggtt tatctgtctg tgtgaccact caggtcggct gtaatatcgg ttgtaccttc
    30421 tgtgcctctg gtttgattaa gaagcagcgt gacctcaata acggtgaaat cgtagcgcaa
    30481 atcatgctgg ttcagaaata ctttgatgag cgtggtcagg atgaacgcat cagccatatc
    30541 gttgtcatgg gaatcggtga gccctttgat aattacaaca atgtcttgaa tttcgtttgt
    30601 actatcaatg atgataaagg aatggctatc ggtgctcgtc acatcacgat ttcaacctca
    30661 ggtttggctc ataaaattcg tgactttgct gatgaagggg ttcaggtcaa tcttgccgtg
    30721 tctcttcacg cacccaacaa tgaacttcgt tcaagtatca tgaaaattaa ccgtgccttt
    30781 ccgattgaaa aactctttgc tgctattgaa tactatattg agacaacaaa ccgtcgtgta
    30841 acctttgaat atatcatgct taatgaagtc aacgacggtg tagaacaagc cttggaattg
    30901 gctgaattgc tcaagaacat caagaaattg tcttatgtaa acttgattcc ttataaccca
    30961 gttagtgagc atgaccaata tagccgtagt cccaaagagc gcgtgttggc tttctatgat
    31021 acgcttaaga aaaaaggggt caactgtgtg gttcgtcaag agcatggtac agatattgac
    31081 gcagcttgtg gacaattgcg ctctaacaca atgaaacgtg accgccagaa ggcagtcgca
    31141 gcggtaaatc cttaatgatg aagaagactt ataatcatat tttggtctgg ggagtcattt
    31201 tctatagcat ttgcattgtc tgtttttgct ttactcctca agaacaatct accgtgggag
    31261 tgggaactcc aggtattcag catcttggac gcctggtttt tcttttgact cctttcaatt
    31321 ctctctggaa actgggcgaa gtgagtgaca ttggacaatt atgttggatt tttttacaaa
    31381 atatcctcaa tgtcttcttg ttttttcctc tgattttcca actcctttat ctatttccaa
    31441 atttgcggaa aacaaaaaag gtccttcttt ttagttttct tgtgagtctt ggaatcgagt
    31501 gtacgcaatt aatcttggac tttttctttg atttcaatcg cgtctttgag attgatgatt
    31561 tgtggaccaa cactttgggt ggctatctgg cttggctcct ttataaacga ttacataaaa
    31621 acaaggtaag gaattaaaat gagtatttta gaagttaaaa atctgagtca cggttttggt
    31681 gaccgtgcaa tttttgaaga tgtgtccttc cgtctcctca agggagaaca tatcggcctg
    31741 gtcggtgcca atggtgaagg aaaatcaacc tttatgagta tcgtgactgg taaaatgctg
    31801 ccagatgaag gaaaggttga gtggtccaaa tatgtgacgg ctggttactt ggatcagcac
    31861 tctgtccttg ctgaaagaca gtcggtgcgt gatgttctcc gtacggcttt tgatgagctt
    31921 ttcaaagctg aagctcgtat caatgacctc tatatgaaaa tggctgaaga cggcgcggat
    31981 gttgatgctc tcatggaaga agtaggagaa cttcaagacc gtctggagag tcgtgatttc
    32041 tataccttgg atgctaagat tgacgaagta gcgcgtgctc ttggtgttat ggactttggg
    32101 atggatacgg atgtaacttc tttgtcaggt gggcaaagaa ccaaggtgct tttggcaaaa
    32161 cttctccttg aaaagcctga tattttgctg ttggacgagc cgaccaacta cttggatgct
    32221 gagcatattg attggctcaa gcgctatctc caaaactatg agaatgcctt tgttcttatt
    32281 tcgcacgata ttccattcct caatgacgtt attaatattg tctatcatgt ggaaaatcaa
    32341 cagctgacgc gttactctgg tgactactac cagttccaag aagtttatgc tatgaagaaa
    32401 tctcagctag aggcagccta cgaacgccag cagaaagaga ttgcagacct caaggacttt
    32461 gtggctcgta ataaagcccg tgttgcaact cgtaatatgg ctatgtctcg tcaaaagaaa
    32521 ttggataaga tggatattat cgaactccaa agtgagaaac caaaaccatc ctttgatttc
    32581 aaaccagctc gtacaccagg gcgctttatc ttccaagcca agaacttgca aattggttac
    32641 gaccgtcctc ttactaagcc tttaaatctt accttcgaac gcaatcaaaa ggttgcgatt
    32701 attggtgcta atggtattgg aaaaacaact ctcttgaaga gtctcttagg cattatctcg
    32761 ccaatcgctg gggaagtgga gcgtggagat tatttagaac ttggttattt tgagcaggaa
    32821 gtagaaggcg gtaatcgcca aactcctctt gaagctgtct ggaatgcctt tcctgccctt
    32881 aatcaagcag aagtccgtgc agcccttgcc cgttgtggtt tgacaaccaa acatattgaa
    32941 agccagattc aagtattatc agggggagag caagccaagg ttcgtttctg tctcttgatg
    33001 aatcgtgaaa acaacgtttt agtgctggac gagccgacca accatttgga tgtggatgca
    33061 aaggatgagc tcaaacgcgc tctcaaagaa tacaggggat ctatccttat ggtctgccac
    33121 gagccagact tttatgaagg ttggatagac caaatatggg attttaataa tttaacttaa
    33181 gaatgagagt aaaagaaata cagtaccgaa tgtggatact gtattttttt ggtttttaag
    33241 atttaaaatc gtagtctttc accacttcga tgctgtcgat tgtgatagca gtagttggct
    33301 tgtctttttc atctttttcg gctttagcaa tcttatccac aacatccata ccgtcaatca
    33361 cttgaccaaa gactgggtgt ttgccatcta gactagggtt tccaccttct ttgtaggctt
    33421 cgataatttt ctgtggatac ttgcttgtag ggagtttaga agaggtatct gtagagtttt
    33481 ggttgatgaa gaactggctg ccattggtgt ttggttgacc agtattagcc atagcaagag
    33541 caccacggat gttatacaaa taaggagtaa tctcgttctt gaaaccagtt cctttgtctt
    33601 tagtcttatc cttgtcatgc catatggact gaccacctgt accgtcccct tttggatctc
    33661 cagtttggac cataaagcca tcgatgacac ggtggaaggt aataccgtta tagtagcctt
    33721 ctttggcgtg agtgaggaaa ttttcaaccg ctagaggagc gagtttaggg aagagtttaa
    33781 tgcgaatatc accttggctt gtgtggagaa tcacttcggc ttcatcttca gcaacttcct
    33841 tagatagttg tgggaaattg gcgttttcgt ttgttaaagc atcgtttaac tccttggcag
    33901 attgggcagc tactttggaa ctttcttcag cagcaagact ggaatcaaca taatcatcac
    33961 cacgcagact gcgttggacg ctgctacacc cagctagggc tacagtagac agtaaaagaa
    34021 gggttgctag ttttttcatt ctgatcctct caaaaattca tttataccat tgtaccctaa
    34081 aaggaagtgg atttcaaata ttagtagttt acagaactgg cttagataat agttgggatt
    34141 tcatcatcat cttgaaaatc ttcaacttct tcaacttctt ccccagtaaa tggtttctga
    34201 aaagaactta gtataaaacg ggcaattggt tcaacaatta ggaaatttag aggaagagct
    34261 gcaataaagt ttacgaacca ggcgcttaga taggtattgg gtgtgatagc aatgccattg
    34321 taaaaaagtc catagaagga catgaaagtg accagctaat tcttcttctg aaaaatgctc
    34381 atgaagggct tgatccaggt cgcaagattt cattttagaa agtccagtaa ctcccttctt
    34441 cttcaggata ttctttttca tggtattatt tagatggtca agtgagtcaa aagaagtttc
    34501 gacaagagca tacccttttt ctaccagagt ttttagatgt ttaggggcat caataccata
    34561 agtgtactca aagtattttg gaaaccagat cttaagaaag ctcgtaaagc tagccagttc
    34621 tctaaacgct aagaactagc tacaacacag catttacaac acttcatggt tcacaccatg
    34681 gggtgttttt taatgatttt aagcaaaatt cacacttaat tgaaagttat ttaaattaga
    34741 tgaaaattta ttttttgaaa aagtgggaaa acattgattc taagcgaatt ttgaatcata
    34801 ttcgaatggg agtttttaaa atcatgtttc agtggtaaaa gtaccaaact ggattctcca
    34861 tagtaaaatg atatctcctg ctagtgaatc atctgctaat aagtccatat ttcgcttggg
    34921 acttagaagc caagtatcca actctcgttc aggcgatatg aagggtttga cttggtgttc
    34981 tttataaaat ttttctaaaa tagtattcac ggatagcatc tttcaaacat ttatttccta
    35041 ttctaacaaa tttctaaatg ctttaagaaa tttatagtct gtcaagtttt tttcttgaca
    35101 cctgccagaa atctgctata atagaacatg tgctaaatag ctcagctatt tcaccgaaat
    35161 aaaaaattaa agaaatgaga ctttaaaaat ggcagttaaa atccgtttga ctcgtatggg
    35221 ttctaagaaa aaacctttct accgtatcaa cgtagcagat tcacgttcac cacgtgacgg
    35281 acgtttcatc gaaacagttg gaacttacaa cccacttgtt gctgaaaacc aagtaacttt
    35341 gaaagaagac cgcgttcttg catggttggc taatggagct caaccttcag acacagtacg
    35401 taacatcctt tcaaaagaag gcgtattgaa aaaattccac gattctaaat tctcaaaata
    35461 agtttaaagt aggttgacag atggatacga ttgaaaatct cattattgcg attgtgaaac
    35521 ccttaatttc acaaccagat gccttaacta tcaagattga ggatacacca gaatttttgg
    35581 aatatcattt gaatcttgat caaagcgatg tgggtcgtgt aatcggtcgt aagggtcgca
    35641 ctatttctgc gataagaacg attgtctact ctgtcccaac tgaatacaaa aaagtaagaa
    35701 tcgttattga cgaaaaataa gaagggcggg acggatgtct cgcttttttg tgtggaatag
    35761 aagatatagt aaaatgaaat aataacagga caaatcgatc aggacagtca aatcgatttc
    35821 taacaatgtt ttagaagtaa aggtgtacta ttctagtttc aatatactat aaaagattga
    35881 acgtttaggc aattccaaga ctacttaatc gaacattaac agcagtctcg gactgatgaa
    35941 ggtcttttta tgaagttagt ggaggaagtc ggagaagtag ccgaggtttt gaataggcgc
    36001 tctggtcgaa aagaagggat aggattcgaa cgaggaactt gccagagaac tggctgatat
    36061 catttactac accgtcgcaa tcgtagctat taatcatatt gaccttacca agactgtctt
    36121 tgagaaagac aaaaccgcag ccgttaatta ccaacataaa cataatttgg aaggattatt
    36181 gaagggaaag tagagatatt gtccccttcc tccaacttga gaaaatcctt ggaacgtgat
    36241 aaaataaagg ataaggattt ttaataattc attatataga atcagtggat ttctttatga
    36301 agaggtttga agtatctaca gaaattggta gcctctctgt tacttatcaa aagcaaaaga
    36361 aagtgctagt ttgtctaaac ggagcaggtt tgctaccaag ttatgaaaat ttttcactta
    36421 tacttgaaaa acctcctcct acaattggtt atttgacaat tgattttccg aacacaggta
    36481 ggagtccgat tcatgaccaa gctggaaaaa atctagataa tcttgcagat gcggtttatg
    36541 aagtacttga agaattagga atttctgaat atatactttg tgcacatagt tggagtggaa
    36601 ttttagcttg caaattactc gagaaaccaa ttaagcgtca gactttagta gcaattgaac
    36661 cgacaactaa aaaagtcatg tttgctgatt tttcagaaaa tccttatcca gaaatggaag
    36721 agcagatgag gctgattgac gagtgtggtc ctgaacttta ttttaagaac ttaactcaag
    36781 caacatttag tcctgaaacg aataaaaaaa tctgggaatt aatgcaagaa aaaggcttag
    36841 agttggaaaa tcaagatcca gaatttcaga tatctggaga gattactgag gaagattttg
    36901 aggatgtatc tatagaagct catattcctg tatttgtttt ttgtcagcct tatagagaaa
    36961 aagagtacag agaatcagaa tattggactt ccaatactaa actcatttta ggagggaatc
    37021 accattattt acaatggtca gaatcggaaa aaattgcggc tattattcga gaattgttag
    37081 aataagatgg aaaaaaggag attacaggag acaagatgaa ctactttaat gttgggaaaa
    37141 tcgttaatac gcagggatta cagggtgaga tgcgagtctt gtctgtgacg gattttgcag
    37201 aagaacggtt taaaaaagga gctgagctgg ctttgtttga tgaaaaagat cagtttgtcc
    37261 aaacagtgac catcgctagc caccgtaaac agaagaactt tgacattatt aaattcaaag
    37321 atatgtacca tatcaatact atcgaaaagt acaagggata cagtctcaag gtcgctgagg
    37381 aagatttgaa tgacctagac gatggtgaat tttactatca cgagattatc ggtttggaag
    37441 tctatgaggg tgatagcttg gttggaacca tcaaggaaat cctgcaacca ggtgctaatg
    37501 atgtctgggt ggtcaaacga aaaggcaaac gtgatttgct tttaccttat atcccaccag
    37561 tggttctcaa tgttgatatt ccaaataaac gggtcgatgt ggaaatctta gaagggttag
    37621 acgatgaaga ttgatatttt aaccctcttt ccagagatgt tttctccact ggagcactca
    37681 atcgttggaa aggctcgaga aaaagggctc ttggatatcc agtatcataa ttttcgagaa
    37741 aatgctgaaa aggcccgtca tgtagatgat gagccctacg gaggcggtca gggcatgttg
    37801 ctcagagtac aacctatttt cgattccttt gatgctattg aaaagaaaaa tccgcgcgtt
    37861 attctcctcg atcctgctgg aaagcagttt gatcaggctt atgctgaaga tttggctcaa
    37921 gaggaagagc taatctttat ctgtgggcac tatgagggtt atgatgagcg cattaagacc
    37981 ttggtaacag atgagatttc cctaggcgac tatgtcctca ctggtggaga attggcagct
    38041 atgaccatga ttgatgctac agttcgcctg attccagaag tgattggcaa ggagtctagc
    38101 caccaagatg atagtttttc ttcaggtctt ttagaatatc ctcagtacac acgtccttat
    38161 gattatcgag gcatggtcgt gccagatgta ttgatgagtg gccaccatga aaagattcgt
    38221 cagtggcgat tgtacgagag tttaaagaaa acctacgagc gcagaccgga tttacttgaa
    38281 cattatcaac tgacagtaga agaagaaaaa atgctggcag aaatcaaaga aaacaaagaa
    38341 taaaggagaa acctatgcaa gtaatcaaac gtaatggcga aattgctgaa tttaatccag
    38401 ataagattta ccaagccatc ttgaaggcag cccaaactgt ttatgttttg acagatgatt
    38461 tgcgtcaaaa tcttgctcaa gtcactaaga aggtagtttt ggatttacaa gaagccaagg
    38521 tggaacgtgc gactatcagt atgattcaat ctatggttga acatcgttta ttgggcgcag
    38581 gttacattac cattgcagaa cactacattt cctatcgttt acaacgtgac ttggaaagaa
    38641 gtggttatgg agatcatatc gcagttcatt tacattttga acaaattcgc taagaaaaaa
    38701 gagtgggatg aagcaactac atctcactct ttcttaaatc tatttttttg ggctgtttgg
    38761 acagttgagg ggacaaatcg caggcgttga atatcgctta tacggataat ccggctcaca
    38821 tttttggaaa aatttttcac gataatttgc tggccttgct gatcatattt gatgatgtca
    38881 cctgtaaagc ttgtctcaga taagataagg tgaacagcgg tttgtttctg gatagcctct
    38941 tcaatagtgg ctgtaaggga gttggtttca gtctggtcag gttggtcata tccatttaaa
    39001 aaatcatgta ttttatttag aacttgctgg aatttatgtc tcatattggc ctcccttctt
    39061 ttatatcaat attatataaa attttcctaa aatctacaag attttacgaa taaactaatg
    39121 aaactaaaaa aggagaagaa aatggcagaa tttacatttg aaatcgaaga gcacttgttg
    39181 actctttctg aaaacgaaaa aggttggacc aaggaaatta accgtgtgag ctttaatggt
    39241 gcccctgcaa agtttgatat tcgtgcttgg agtccagacc atactaaaat gggcaaaggg
    39301 attactctct caaatgaaga atttcaaacg atggtggatg cctttaaagg caactaatac
    39361 tcttcgaaaa tctcttcaaa ccgcgtcagc tttgccttgc cgtatgtatg gttactgact
    39421 tcgtcagttt catccacaac ctcaaaacaa tgttttgagc tgacttcgtc agtttcatcc
    39481 acaacctcaa aacaatgttt tgagctgact tcgtcagttt catccacaac ctcaaaacag
    39541 tgttttgagc agcctgcggc tagcttccta gtttgctctt tgattttcat tgagtataag
    39601 ttttcaaaat aaaagaaaag gatattgagt catgataact cggtatcctt ttttagttag
    39661 taaagtaagc ctgattttta aggcgttgaa gtaggggacg gctaataaaa ctaatagcca
    39721 gaagtttgcc aaggtctgga atgataaagg gaagaacccc cacaacaaga gctttttcaa
    39781 atgccattcc agctaggaaa tgcaagctga gaatcccgcc gacaaagaca agggcatcac
    39841 ccaagaggtt tgcaagaaaa atcttaacaa caccactctt gctgttggtt agagaggaag
    39901 taagtccaga gtaaacgaga taaaaccaaa gatagcctgc agtagggcca actaaagcct
    39961 gaaaaccagc tccacctcct gcaaagacag gaagaccgat agcacctaga agaagataga
    40021 gtccagcaga aagtacagcc tctctcggtc taaagacagt agcaatcaag ccgattgcaa
    40081 agttttgcag agtgaaggga acaggtccaa ttggaagact gatttgtgcc aaagcagcaa
    40141 tgagagcagc cccaatagca gggatagcat aaacgtgagc ttttttcaaa atagttaacc
    40201 tcttttctaa tgtatagtaa ctattatact catataggag tcgatgtcaa ccatttttta
    40261 aaaacaaggt aacaaaaact gtaacagccg attttcgtga ctagtcaagt tggataattt
    40321 ttttgttgat tcgaaaatca ttaaaaaaga agcagacata tttatatcag cttcttttgt
    40381 ttcgattaac gcatggttac aaattcttca gatgcagttg ggtgaattgc cacagttgca
    40441 tcaaagtcag ccttggttgc tcccattttg atagcaacgg caaatccctg aatcatttca
    40501 tcaacgccgt agccaattcc atgaagtccg acaacttttt cttctgaacc agctgttatg
    40561 agtttgaaac gggattcttg acggttgcga gtgcaagcag agtacataga tgcaaagctt
    40621 gatttataaa ccttgatttg gtcttgaccg tattctttaa tagcttgctc ttctgtcaaa
    40681 ccaacagttc cgatagcagg gtgtgaaaag acaacagttg gaatagttga gtaatccatt
    40741 tttgcagtag tttttccgtt aaagagacgt tcagataggg tacgtccggc cttgattgca
    40801 actggagtca gttctttctc gcccgttaca tcacctagag catagagtcc ctcaacaaca
    40861 gtattttggt attcatccac ttggataaag ccacgttcgt tcagagtcac tccagctttt
    40921 tcaagttgca agcccttaac gtttggacgg cggcctgtag cccagataac ttggctagct
    40981 gtgtgactag taccatcttc gaaatgaatg gtaatgccgt cagtagtttt ttctaacttg
    41041 acagggactt tgtgagtgtg aagtggtaag tttgttcttt ccatttcctt gaccaaacct
    41101 tcaacgatgt aggaatcaaa accacgtaaa ggacgatcgc ggcgaacaaa gagatctgtc
    41161 ttgacaccaa aagtgtggag tacgccagct aattcaacgg cgatataacc agcgcctaga
    41221 atggcaactg actctggaag ttcttcccag gcaaatacat catcagaaga gccacctagc
    41281 tcagcaccag gaatattagg aatacttgga tgggcacctg tagcaatcac gatatgttta
    41341 gcacgaatca gttcaccatt tacgcttaca gtatgagaat ctacaaattc agcatgacct
    41401 tcaatcaagt ctacaccgtt gcgtttaaaa ctaccatcat aagaagaacg agcgcgatca
    41461 atgtaggctt cacgattgcg acgtagggtt gcaaagtcaa agttaagatc agtagtctta
    41521 aagccgtagt cttctccaaa ttgatggaaa gtctcagcga tttgcgcccc gtaccacatg
    41581 atttttttag gaacacaacc gacgttgaca caggttccac ctaatttctt ttcctcaata
    41641 acggctgctt tggctccatg ttcaccagca cggttcatgg tagcgattcc tccgctacct
    41701 ccaccgatag caatgatatc atattctctc attgaaaact cctttgtaat cttttaaata
    41761 gtagagcgtc ttttttgata gttatatttt attctttttt tgatttgatt gcaaaaatct
    41821 gctacgcaca aaaaattgca aaaaagcttg ccaaataagt caagatagtg tattatatat
    41881 ctagtacaat agaaaagcaa aattccgaac gattgtttaa tcctgaactg ccattatttc
    41941 catctgaact gcattgtttg ctggagggaa atttggtata atagcaaagt attgtaaaaa
    42001 agaaaaggag tttcattatg aagaaaaaga atggtaaagc taaaaagtgg caactgtatg
    42061 cagcaatcgg tgctgcgagt gtagttgtat tgggtgccgg ggggatttta ctttttagac
    42121 aaccttctca gactgctcta aaagatgagc ctactcatct tgttgttgcc aaggaaggaa
    42181 gcgtggcatc ctctgtttta ttgtcaggga cagtaacagc aaaaaatgaa caatatgttt
    42241 attttgatgc tagtaagggt gatttagatg aaatccttgt ttctgtgggc gataaggtca
    42301 gcgaagggca ggctttagtc aagtacagta gttcagaagc gcaggcggcc tatgattcag
    42361 ctagtcgagc agtagctagg gcagatcgtc atatcaatga actcaatcaa gcacgaaatg
    42421 aagccgcttc agctccggct ccacagttac cagcgccagt aggaggagaa gatgcaacgg
    42481 tgcaaagccc aactccagtg gctggaaatt ctgttgcttc tattgatgct caattgggtg
    42541 atgcccgtga tgcgcgtgca gatgctgcgg cgcaattaag caaggctcaa agtcaattgg
    42601 atgcaacaac tgttctcagt accctagagg gaactgtagt cgaagtcaat agcaatgttt
    42661 ctaaatctcc aacaggggcg agccaagtta tggttcatat tgtcagcaat gaaaatttac
    42721 aagtcaaggg agaattgtct gagtacaatc tagccaacct ttctgtaggt caagaagtaa
    42781 gctttacttc taaagtgtat cctgataaaa aatggactgg gaaattaagc tatatttctg
    42841 actatcctaa aaacaatggt gaagcagcta gtccagcagc cgggaataat acaggttcta
    42901 aataccctta tactattgat gtgacaggcg aggttggtga tttgaaacaa ggtttttctg
    42961 tcaacattga ggttaaaagc aaaactaagg ctattcttgt tcctgttagc agtctagtaa
    43021 tggatgatag taaaaattat gtctggattg tggatgaaca acaaaaggct aaaaaagttg
    43081 aggtttcatt gggaaatgct gacgcagaaa atcaagaaat cacttctggt ttaacgaacg
    43141 gtgctaaggt catcagtaat ccaacatctt ccttggaaga aggaaaagag gtgaaggctg
    43201 atgaagcaac taattagtct aaaaaatatc ttcagaagtt accgtaatgg tgaccaagaa
    43261 ctgcaggttc tcaaaaatat caatctagaa gtgaatgagg gtgaatttgt agccatcatg
    43321 ggaccatctg ggtctggtaa gtccactctg atgaatacga ttggcatgtt ggatacacca
    43381 accagtggag aatattatct tgaaggtcaa gaagtggctg ggctgggtga aaaacaacta
    43441 gctaaggtcc gtaaccaaca aatcggtttt gtctttcagc agttctttct tctatcgaag
    43501 ctcaatgctc tgcaaaatgt agaattgccc ttgatttacg caggagtttc gtcttcaaaa
    43561 cgtcgcaagt tggctgagga atatttagac aaggttgaat tgacagaacg tagtcaccat
    43621 ttaccttcag aattatctgg tggtcaaaag caacgtgtag ccattgcgcg tgccttggta
    43681 aacaatcctt ctattatcct agcggatgaa ccgacaggag ccttggatac caaaacaggt
    43741 aaccaaatta tgcaattatt ggttgatttg aataaagaag gaaaaaccat tatcatggta
    43801 acgcatgagc ctgagattgc tgcctatgcc aaacgtcaga ttgtcattcg ggatggggtc
    43861 atttcgtctg acagtgctca gttaggaaag gaggaaaact aagatgcaga atctgaaatt
    43921 tgccttttca tctatcatgg ctcacaagat gcgttctttg cttactatga ttgggattat
    43981 tatcggtgtt tcatcagttg ttgtgattat ggctttgggt gattccctat ctcgtcaagt
    44041 caataaagat atgactaaat ctcagaaaaa tattagcgtc tttttttctc ctaaaaaaag
    44101 taaagacggg tcttttactc agaaacaatc agcttttacg gtttctggaa aggaagagga
    44161 agttcctgtt gaaccgccaa aaccgcaaga atcctgggtc caagaggcag ctaaactgaa
    44221 gggagtggat agttactatg taaccaattc aacgaatgcc atcttgacct atcaagataa
    44281 aaaggttgag aatgctaatt tgacaggtgg aaacagaact tacatggacg ctgttaagaa
    44341 tgaaattatt gcaggtcgta gtctgagaga gcaagatttc aaagagtttg caagtgtcat
    44401 tttgctagat gaggaattgt ccattagttt atttgaatct cctcaagagg ctattaacaa
    44461 ggttgtagaa gtcaatggat ttagttaccg ggtcattggg gtttatacta gtccggaggc
    44521 taaaagatca aaaatatatg ggtttggtgg cttgcctatt actaccaata tctcccttgc
    44581 tgcgaatttt aatgtagatg aaatagctaa tattgtcttt cgagtgaatg ataccagttt
    44641 aaccccaact ctgggtccag aactggcacg aaaaatgaca gagcttgcag gcttacaaca
    44701 gggagaatac caggtggcag atgagtccgt tgtatttgca gaaattcaac aatcgtttag
    44761 ttttatgacg acgattatta gttccatcgc agggatttct ctctttgttg gaggaactgg
    44821 tgtcatgaac atcatgctgg tttcggtgac agagcgcact cgtgagattg gtcttcgtaa
    44881 ggctttgggc gcaacacgtg ccaatatttt aattcagttt ttgattgaat ccatgatttt
    44941 gaccttgtta ggtggcttaa ttggcttgac aattgcaagt ggtttaactg ccttagcagg
    45001 tttgttactg caaggtttaa tagaaggtat agaagttgga gtatcaatcc cagttgccct
    45061 atttagtctt gcagtttcgg ctagtgttgg tatgattttt ggagtcttgc cagccaacaa
    45121 ggcatcgaaa cttgatccaa ttgaagccct tcgttatgaa tgagatcaac aagatggaca
    45181 ctcgtctatc ttgtttttgt atggatttcc ctatcgaaat tcattaaaaa tgtgatataa
    45241 tgaagtgtta gaaaaacagg tttcatttgc ctggaaagga aaaattatgt ctgaaaaaaa
    45301 tttttatatt acaacgccga tttactatcc atctgggaaa cttcatatcg gttctgccta
    45361 cacaactatc gcatgtgatg tcctagcacg ttacaaacgc ctgatgggct acgatgtatt
    45421 ttatctgaca ggtcttgatg aacatggtca gaaaatccag cagaaagcgg aagaagctgg
    45481 tattacacct caagcctatg ttgatggaat ggcggttgga gttaaagaac tctggcaatt
    45541 actagatatc tcatacgata aatttatccg tacaactgat gactaccatg aaaaagttgt
    45601 tgcacaggtc tttgaacgct tacttgctca agatgatatc tacttgggtg aatactctgg
    45661 ttggtattca gtatcagacg aagaattctt tacagaaagc cagctggcag aagttttccg
    45721 tgatgaagct ggaaatgtga ctggtggtat tgctccatca ggtcatgagg ttgaatgggt
    45781 ttctgaagaa tcatacttcc ttcgccttag caaataccaa gaccgtttgg tcgaattttt
    45841 caaagctcat cctgaattta tcacgccaga tggtcgcctt aatgaaatgc tacgcaactt
    45901 catcgagcca ggtttggaag atttggcggt atctcgtaca acctttacat ggggagtgcc
    45961 tgtcccatca aatccaaaac acgttgtcta cgtttggatt gatgcccttc ttaactatgc
    46021 gacagctctt ggctacgctc aagacgaaca tggtaacttt gacaagttct ggaatggaac
    46081 agtcttccat atggtaggaa aagatatcct tcgcttccac tctatctact ggccaatcct
    46141 tcttatgatg ttggatgtta aattacctga tcgtttgatt gcccatggtt ggtttgtcat
    46201 gaaagacgga aaaatgtcta agtcaaaagg gaatgtcgtt taccctgaaa tgttggtaga
    46261 gcgttatgga ctagatccac ttcgttacta cctcatgcgt aaccttccag ttggttcaga
    46321 cggaaccttt actcctgaag actatgtcgg ccgtatcaac tatgaattgg ctaatgacct
    46381 tgggaacctc cttaaccgta cggtttccat gattaataag tactttgatg gacaaatccc
    46441 tgcctatgta gaaggtgtga ctgaatttga tcatgttctt gctgaggttg cagaacaatc
    46501 aatcgcagac ttccatacac acatggaagc agttgactat ccacgtgcgc ttgaagcagt
    46561 ctggactctg atctctcgta ccaataaata catcgatgag actgcaccat gggtcttgga
    46621 caaggatgaa gctcttcgtg accaattggc aagtgtcatg agccacttgg cagccagcat
    46681 tcgtgtagtt gctcacttga ttgaaccatt tatgatggaa actagtcgtg cagttttgac
    46741 tcaacttggt ttggaagaag tttctagtct tgaaaacttg agtttggctg acttcccagc
    46801 agatgtgact gtagttgcca aaggaacacc tatctttcca cgtctaaata tggaagaaga
    46861 aatcgcctat atcaaggaac aaatggaagg caataaacca gcagtcgaaa aagaatggaa
    46921 tccggacgaa gttgagctca aactaaacaa ggatgaaatc aagtttgaag actttgacaa
    46981 ggttgaaatc cgtgtcgcag aagtcaaaga agtgtctaaa gtagaaggtt cagataagtt
    47041 gcttcaattc cgcttggatg ctggtgatgg agaagatcgt cagattcttt caggaattgc
    47101 aaaatactat ccaaatgaac aagaattggt cggcaagaaa gttcaaatcg ttgctaacct
    47161 caaaccacgt aaaatgatga aaaaatatgt cagccagggt atgattctct cagctgaaca
    47221 tgatggcaaa ttaacccttc tcacagttga tccagctgta ccaaatggaa gtgtgattgg
    47281 gtaaaagtag acaggactag ttcaggctag ttctgttttt ttatttatac tcaatgaaaa
    47341 tcaaagagca aactaggaag ctagccgcgg gttgatcaaa gcactgcttt gaggttgtag
    47401 atgaaactga cgaagtcagc tcaaagcact gctttgaggt tgtagatgaa actga
//
LOCUS       DAVKEV010000012        47118 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVKEV010000012 DAVKEV010000000
VERSION     DAVKEV010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47118
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.012"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..137)
                     /locus_tag="VWZ68_000666"
     CDS             complement(<1..137)
                     /locus_tag="VWZ68_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9371736.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     G"
     gene            307..378
                     /locus_tag="VWZ68_000667"
     tRNA            307..378
                     /locus_tag="VWZ68_000667"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:340..342,aa:Glu,seq:ttc)
     gene            384..457
                     /locus_tag="VWZ68_000668"
     tRNA            384..457
                     /locus_tag="VWZ68_000668"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:418..420,aa:Asn,seq:gtt)
     gene            complement(498..1040)
                     /locus_tag="VWZ68_000669"
     CDS             complement(498..1040)
                     /locus_tag="VWZ68_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEU9371737.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            complement(1300..2553)
                     /locus_tag="VWZ68_000670"
     CDS             complement(1300..2553)
                     /locus_tag="VWZ68_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEU9371738.1"
                     /translation="MKCFVGLDISSTKLDVCIMLSDTSTPVTASLSNDLSGATEIKNH
                     ILDLNHTYHFERIVIGMEATSLYSFHPAMFFHEDRQLKELHVEIMVEQPNKIKKYRDA
                     FEENKNDTIDAFYIADYFRIERFSPSFLKEEKYMALQHLTRTRLQIIEQLTRTKQHFI
                     ENIYYKCNTLAYQFKKEELSTNLWSSTMMTLMTDEMTLDELANMPLQELDDWLQKLGK
                     GHFKDSEKLAQTIQAAIRGSYRLSKLQQDSVNVILGLLAREIRNLEKMIKEIDKAIED
                     MVETIPEYQCLTSIPGVGKVYAAGIIAEIGQIERFKDHPQVAKFAGLNWREKQSGNSN
                     SQHTSLVNRGNRYLRYYLVEAANSVRRYDDEYKDFYKKKYHEVPKHQHKRAILLTARK
                     FVRLVDVLLRNHQLYTPPRRIMEDN"
     gene            2909..4667
                     /locus_tag="VWZ68_000671"
                     /pseudo
     CDS             2909..4667
                     /locus_tag="VWZ68_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
     gene            complement(4697..7240)
                     /locus_tag="VWZ68_000672"
     CDS             complement(4697..7240)
                     /locus_tag="VWZ68_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEU9371739.1"
                     /translation="MKSFLKTYRTYFISLIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLSPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYTLMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVLFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSTYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVDFDY
                     FSPIPYEKIENTNNLISVTSSSNEDAAIQYQIEVPENSQIYLSFINLHFSNDKQKKVD
                     ILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTKTFT
                     EAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQAQT
                     GFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(7302..8924)
                     /locus_tag="VWZ68_000673"
     CDS             complement(7302..8924)
                     /locus_tag="VWZ68_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9371740.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            9130..10155
                     /gene="trpS"
                     /locus_tag="VWZ68_000674"
     CDS             9130..10155
                     /gene="trpS"
                     /locus_tag="VWZ68_000674"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEU9371741.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            10307..11785
                     /gene="guaB"
                     /locus_tag="VWZ68_000675"
     CDS             10307..11785
                     /gene="guaB"
                     /locus_tag="VWZ68_000675"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEU9371742.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(11836..12933)
                     /gene="recF"
                     /locus_tag="VWZ68_000676"
     CDS             complement(11836..12933)
                     /gene="recF"
                     /locus_tag="VWZ68_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEU9371743.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(12936..13304)
                     /gene="yaaA"
                     /locus_tag="VWZ68_000677"
     CDS             complement(12936..13304)
                     /gene="yaaA"
                     /locus_tag="VWZ68_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEU9371744.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            13463..14713
                     /locus_tag="VWZ68_000678"
     CDS             13463..14713
                     /locus_tag="VWZ68_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU9371745.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            14710..15993
                     /locus_tag="VWZ68_000679"
     CDS             14710..15993
                     /locus_tag="VWZ68_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU9371746.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGYVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTIDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            16035..16856
                     /locus_tag="VWZ68_000680"
     CDS             16035..16856
                     /locus_tag="VWZ68_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9371747.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            16867..17412
                     /gene="pgsA"
                     /locus_tag="VWZ68_000681"
     CDS             16867..17412
                     /gene="pgsA"
                     /locus_tag="VWZ68_000681"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEU9371748.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            17409..18236
                     /locus_tag="VWZ68_000682"
     CDS             17409..18236
                     /locus_tag="VWZ68_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU9371749.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            18221..19060
                     /locus_tag="VWZ68_000683"
     CDS             18221..19060
                     /locus_tag="VWZ68_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU9371750.1"
                     /translation="MGIALENVNFIYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPSILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            19053..19847
                     /locus_tag="VWZ68_000684"
     CDS             19053..19847
                     /locus_tag="VWZ68_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU9371751.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            19906..20724
                     /gene="mreC"
                     /locus_tag="VWZ68_000685"
     CDS             19906..20724
                     /gene="mreC"
                     /locus_tag="VWZ68_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEU9371752.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            20724..21218
                     /gene="mreD"
                     /locus_tag="VWZ68_000686"
     CDS             20724..21218
                     /gene="mreD"
                     /locus_tag="VWZ68_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEU9371753.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            21312..22490
                     /locus_tag="VWZ68_000687"
     CDS             21312..22490
                     /locus_tag="VWZ68_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU9371754.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            22714..23493
                     /gene="rpsB"
                     /locus_tag="VWZ68_000688"
     CDS             22714..23493
                     /gene="rpsB"
                     /locus_tag="VWZ68_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEU9371755.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNK"
     gene            23559..24599
                     /locus_tag="VWZ68_000689"
     CDS             23559..24599
                     /locus_tag="VWZ68_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEU9371756.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            24845..25168
                     /gene="tnpB"
                     /locus_tag="VWZ68_000690"
     CDS             24845..25168
                     /gene="tnpB"
                     /locus_tag="VWZ68_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU9371757.1"
                     /translation="MIIQLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSDQV
                     FLFCGGRKDRFKVLYWDGQGFWILYKRFENGKLTWSSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
     gene            complement(25309..25596)
                     /locus_tag="VWZ68_000691"
                     /pseudo
     CDS             complement(25309..25596)
                     /locus_tag="VWZ68_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            25587..25985
                     /locus_tag="VWZ68_000692"
     CDS             25587..25985
                     /locus_tag="VWZ68_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9371758.1"
                     /translation="MKAPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(26182..27102)
                     /gene="cysK"
                     /locus_tag="VWZ68_000693"
     CDS             complement(26182..27102)
                     /gene="cysK"
                     /locus_tag="VWZ68_000693"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEU9371759.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(27387..28022)
                     /locus_tag="VWZ68_000694"
     CDS             complement(27387..28022)
                     /locus_tag="VWZ68_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEU9371760.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHGLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            28078..29376
                     /locus_tag="VWZ68_000695"
     CDS             28078..29376
                     /locus_tag="VWZ68_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9371761.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQVVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            29373..30035
                     /locus_tag="VWZ68_000696"
     CDS             29373..30035
                     /locus_tag="VWZ68_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEU9371762.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            30115..30663
                     /gene="raiA"
                     /locus_tag="VWZ68_000697"
     CDS             30115..30663
                     /gene="raiA"
                     /locus_tag="VWZ68_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEU9371763.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            30799..32772
                     /locus_tag="VWZ68_000698"
     CDS             30799..32772
                     /locus_tag="VWZ68_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEU9371764.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            32769..33221
                     /gene="rplI"
                     /locus_tag="VWZ68_000699"
     CDS             32769..33221
                     /gene="rplI"
                     /locus_tag="VWZ68_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEU9371765.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            33265..34617
                     /gene="dnaB"
                     /locus_tag="VWZ68_000700"
     CDS             33265..34617
                     /gene="dnaB"
                     /locus_tag="VWZ68_000700"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEU9371766.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            34619..34885
                     /locus_tag="VWZ68_000701"
     CDS             34619..34885
                     /locus_tag="VWZ68_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371767.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            34974..36320
                     /gene="cbpD"
                     /locus_tag="VWZ68_000702"
     CDS             34974..36320
                     /gene="cbpD"
                     /locus_tag="VWZ68_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEU9371768.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      36403..36505
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            36576..36866
                     /locus_tag="VWZ68_000703"
     CDS             36576..36866
                     /locus_tag="VWZ68_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEU9371769.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQGADNVFSNVKINVGEILSIDEKLEKYTETTH"
     gene            36829..37587
                     /locus_tag="VWZ68_000704"
     CDS             36829..37587
                     /locus_tag="VWZ68_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9371770.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWFNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            37625..38632
                     /locus_tag="VWZ68_000705"
     CDS             37625..38632
                     /locus_tag="VWZ68_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9371771.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            38632..39360
                     /locus_tag="VWZ68_000706"
     CDS             38632..39360
                     /locus_tag="VWZ68_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9371772.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPQGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            39479..39937
                     /locus_tag="VWZ68_000707"
     CDS             39479..39937
                     /locus_tag="VWZ68_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEU9371773.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            39939..42371
                     /locus_tag="VWZ68_000708"
     CDS             39939..42371
                     /locus_tag="VWZ68_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU9371774.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIATLRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            42692..43345
                     /gene="rr06"
                     /locus_tag="VWZ68_000709"
     CDS             42692..43345
                     /gene="rr06"
                     /locus_tag="VWZ68_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEU9371775.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            43342..44673
                     /gene="hk06"
                     /locus_tag="VWZ68_000710"
     CDS             43342..44673
                     /gene="hk06"
                     /locus_tag="VWZ68_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEU9371776.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            44768..45295
                     /locus_tag="VWZ68_000711"
     CDS             44768..45295
                     /locus_tag="VWZ68_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEU9371777.1"
                     /translation="MVLAIILVIFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLVEAMVHKTMFDGMSMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            45374..>47118
                     /gene="cbpA"
                     /locus_tag="VWZ68_000712"
     CDS             45374..>47118
                     /gene="cbpA"
                     /locus_tag="VWZ68_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpA"
                     /protein_id="HEU9371778.1"
                     /translation="MFASKSERKVHYSIRKFSVGVASVVVASLVMGSVVHATENEGAT
                     QVPTSSNRANESQAEQGEQPKKLDSERDKARKEVEEYVKKIVGESYAKSTKKRHTITV
                     ALVNELNNIKNEYLNKIVESTSESQLQILMMESRSKVDEAVSKFEKDSSSSSSSDSST
                     KPEASDTAKPNKPTEPGEKVAEAKKKVEEAEKKAKDQKEEDRRNYPTITYKTLELEIA
                     ESDVEVKKAELELVKVKANEPRDEQKIKQAEAEVESKQAEATRLKKIKTDREEAEEEA
                     KRRADAKEQGKPKGRAKRGVPGELATPDKKENDAKSSDSSVGEETLPSPSLKPEKKVA
                     EAEKKVEEAKKKAEDQKEEDRRNYPTNTYKTLELEIAESDVEVKKAELELVKEEAKEP
                     RNEEKVKQAKAEVESKKAEATRLEKIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPA
                     PAPKAEKPAPAPKPENPAEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPA
                     QPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYY
                     LNANGSMATGWLQNNG"
BASE COUNT        14872 a         7766 c        10119 g        14361 t
ORIGIN      
        1 tttcctttct gttgataggc tagtaacaga cgattgattt gtctttcaga aagattgagt
       61 tcgacacagg cccgtttctt tgttttcttt ccttgggcta tagcttttat cacaagatat
      121 tttttcgttt cattcatatt cagttggatc cttttcatat gactattcta ccaaatggga
      181 cattttcacg ttcgatttac taaagacatt atcacattcg aattacatat tttagagaaa
      241 aaatctcaaa agtgattgac aattagcaag aaattgatat aatggttata tctgctacag
      301 atagaaggtc cgttggtcaa ggggttaaga caccgccttt tcacggcggt aacacgggtt
      361 cgaatcccgt acggactatt ttatccgcca tagctcagtt ggtagtagcg catgactgtt
      421 aatcatgatg tcgtaggttc gagtcctact ggcggagtat agataaaagg gaacacagct
      481 gtgttcctct ttttgtatca atttgtatca ccaagcattt tcataaggaa gtctgttatt
      541 tcttgagaac tttctttttt tccatgtgca atccaagttt ggcagacacc aaaaagtgca
      601 tgagttagat agatgctact atattctaat tcagtggtat ttagattcag ttgcataaat
      661 cgcttttgta aatctgtact aagcatgata tgaagtttat ttcgtaagaa attttggatt
      721 tctttagtcc cattttcaga aagaagggca gccagaagtg gttctgactc tagatattca
      781 aaaacttcta aaatagcgtc tcttttgtga tgagcatgtt tttgaaaaat atattcaaat
      841 gtatggaata gcttgctttg atagtgctca atcatatcat acttatcctt atagtgagta
      901 tagaagctgg aacgactaat tccggctttt tctactaatt tgacagtaga aattttatca
      961 aatggctgtt ccatcagtaa ttgtaccata gcgttttcaa tagttcgctt tgtttttaag
     1021 cgtttgttac tttcttgcat atttcctcct tgtaaacaaa ttagactata tgtctaaaaa
     1081 tagatttttt atcttgtaat ttagattttt taatgtataa tctattatat caaaatttta
     1141 gacaatatgt ttaaaaaagt ctagtggtaa aatgtcaagc gaccccccgc tcaaagtttg
     1201 aaaactattt caaaaaaagg gtgcactaaa gaagccctac tgaaaacgat gttttcacac
     1261 tgtttttagt agattttcaa ggagaggtgc agatataact tagttatctt ccataatcct
     1321 ccttggtggc gtatagagtt gatggttgcg tagtagcaca tccaccagac gcacaaattt
     1381 tctagcggtt agtaagatgg ctcgtttgtg ttggtgttta ggtacttcat ggtatttctt
     1441 cttatagaaa tccttgtatt cgtcatcata acgccttacc gagttggcgg cttcaaccag
     1501 gtagtagcgc agataacgat tgcccctatt cacaagcgaa gtatgttgtg agtttgagtt
     1561 accagattgc ttttctctcc aattcagacc agcaaatttt gcgacctggg gatggtcttt
     1621 aaagcgttcg atttgtccaa tttcggcaat gataccagca gcgtagacct tcccgacccc
     1681 aggtatggag gtcaggcatt gatattcagg aatggtttcc accatatctt caatggcctt
     1741 atcaatttcc ttgatcattt tttccaggtt tcgaatttcc cgagccagaa gtccgagaat
     1801 gacattgact gaatcttgtt ggagtttaga gaggcgataa gaacctctga tagcggcttg
     1861 aatggtttga gcaagcttct cagagtcctt aaaatgccct ttacccagtt tttggagcca
     1921 atcatctaat tcttgaagag gcatgttagc aagttcgtct aaggtcatct catctgtcat
     1981 caaggtcatc atcgttgaac tccataggtt agtagagagt tcttctttct tgaattgata
     2041 agccaaggta ttgcacttgt agtagatatt ttcaatgaag tgctgtttgg ttctggttaa
     2101 ttgctcgatg atttggagtc tggttcttgt gagatgttgg agagccatgt atttctcttc
     2161 ttttaaaaaa gaaggtgaaa atcgctcaat acggaaataa tccgcaatgt agaaagcatc
     2221 aatggtatcg tttttgtttt cttcgaaagc atcccgatac ttcttgattt tattaggttg
     2281 ttcgaccata atctcaacat gtagttcttt caactgccta tcttcatgga agaacatagc
     2341 agggtggaaa ctgtagagac tggttgcttc catgccaatg acaatccttt cgaagtgata
     2401 ggtatgattc aaatcaagga tatgattctt aatctctgtt gccccagaaa ggtcattaga
     2461 gagggaagca gtgacggggg tgctagtatc actcaacatg atacacacat ctaattttgt
     2521 agagctgatg tctaaaccga caaaacattt cattaaggaa ggtctccttt ccattagatt
     2581 tggaagtttt tttgactact gtaaggtttc ccagaaacac cttgttccaa catcctcgca
     2641 taagagaatc cttatcacag cctgacagag ccgcctgcat cctactagat acagaagtca
     2701 agctgtggaa acagctagtg tgttggaagt ttgaacaagg cttgggtaac agacttttta
     2761 atgaagtcca agcaacaagg agaaaaagaa acaaccatga gtccattcca tgactctatt
     2821 gttctagaaa accttgcaat agtcaagtga taacgaataa aacttgggat tgaaatatcc
     2881 ccatgattat atattacgag gagaaactat gtttaaagaa tggaaagcaa tttaaaaaaa
     2941 acaaccttta ttattgtcat gatcgggatt tctcttattc cagctctgta caatatcata
     3001 tttttgtcat caatgtggga tccatatggg caattgtctg acttacctgt ggcagttgta
     3061 aataatgata aagaggcttc ctataatggt aatactatgg caataggaaa agacatggtg
     3121 tccaatttaa aagaaaataa aaccttggat tttcattttg tagatgaaga ggaaggaaag
     3181 aagggattgg aagatggcga ttactatatg gtagtgactt taccaagtga tttatctgaa
     3241 aaagcaacta cattatccaa tattcaatcg acagcagctt atcaatcatt gacaagtgag
     3301 caacaaactg agataagtga ttctgtatct caaaattcaa ctgatagtat tcaatcggct
     3361 cagtcaattg tagctttagt acaagattta cagggaagtt tagaaaactt acaaaatcaa
     3421 tcttctaatc tttcgacttt aaaaaatcaa gctaatcaag tattacctat tacttctact
     3481 tctttgatag gattgtcaag tggattaaca gagatacaag gagatgttac tagcaaatta
     3541 gttcctgcca gtcagtcgat tgcatcaggt gtaaacgcat atactacagg tgttgataaa
     3601 gtttctcagg gcgcaagtca actaagtgaa aaaaatgcta ccttgacagg tagtttggat
     3661 caattagttt caggctcaaa caccttgaca caaaaatctt ctagcttgac agcaggagtt
     3721 ggtcaattag ttgaaaaaac tccagaatta gtatctggta ttgaaaaatt atcaactggc
     3781 tccaattaat tgaatcaaaa gagtcaagaa ttgatagcag gagttgataa attgcagtca
     3841 ggctctagcc aactagctga caaatccagt cagttacttt caggtgtttc tcaattagaa
     3901 agtggagcta ataaattggc agatggagct gggaaactag cagaaggtgg aacaaagtta
     3961 acttctggat tggaaggttt acagacagga cttgcttctt taggacaagg actaggtaat
     4021 gctagtgatc aactcaaatc agcatcaaca gaatctaaaa atgcagagat tttgtcaaat
     4081 ccactcaatc tttccaaaac agacaatgac caagttcctg taaatggaat tgcaatggct
     4141 ccttatatga tatcagttgc tctttttgtt gcagcaatat caacgaatat gatctttgcg
     4201 aagttacctt caggacgtca tccagagagc cgttgggctt ggttgaaatc tcgagctgaa
     4261 ataaatggta ttatagctgt tttggcaggg attttggtat atggaggagt tcatcttatt
     4321 ggtctaactg ctaatcatga aatgagaaca tttattctca tcatcttaac aagtttagta
     4381 ttcatgtcta tggtgaccgc tttaacaaca tggaatagcc gtataggagc tttcttctcg
     4441 cttatttttc ttttattaca gttagcatca agtgcaggta cctatccgct tgctttgaca
     4501 aatgatttct ttagagctat taatccttgg ttgccaatga gttattcagt ttcgggatta
     4561 cgacaaacaa tctccatcaa caagtcattt tcctagctgt catactagct ctatttactg
     4621 gtttaggtat gctagcctat caacctaaga aaatggaaga agattaaaaa aatcgaccga
     4681 ttaactggtc gattttttat gccttagatg actttcgtct gtgattatag attccaaata
     4741 gtaagagaga agtaaaggaa cagattgctc cagtaataaa accattggga atgaaggaaa
     4801 gtgtaatagt tcctttcccc ttgggaatgt caactttcat aaatccagtt tgagcttgtt
     4861 taatttctat tttcttacca tcttggtagg cagaccaacc tttgtcataa ggaatggtga
     4921 agaaaataga tgtatcttgt tggacatcat atgtagcaaa aaccttgttt ttagaagttg
     4981 atactgtgac aggttgttct ttaatttttt gaattgcctc ggtgaaagtt ttggtatcta
     5041 aacgatagaa ggtaggagat tcaaatgata cttgtgaatt tccagggaaa ctaacattga
     5101 tattgaaagt ttttttctct ttagtatatc ctagattaaa gaaggagaag acattatcag
     5161 ttgtaaaagt ctttttttca ccatttacaa ggatgtcaac cttcttttgt ttatcgttag
     5221 aaaagtgaag gtttatgaaa gagagataaa tttggctgtt ttctggaact tcaatttgat
     5281 actggattgc tgcatcctca tttgaagaac ttgtgacact aatcaaatta ttagtatttt
     5341 ctattttttc ataagggatt ggagaaaaat aatcaaaatc aacgttagca agttgattta
     5401 aaaacgaggc ctgattatcc aaggtatgtt cattgaactt gacatcattg taaacagatt
     5461 gactagcaac tgcaatcgga agagagtatt gattttcata tagggtaaga ttatcttttt
     5521 gatagatatc tttaaaacca tacttatcaa taggactgtc tgagatattg tactggatac
     5581 caaataaact atcagccaaa atactattat ttgcatatcg gagattgaga ttagtcccag
     5641 aggatttaaa cccaagttta tctaaagtag agcttgatga acgatttcga acagatgaaa
     5701 attgagagat tccattgtag ttgaatttca tactgtcatt tcctgtctga gtttgtagtt
     5761 tttcagtacg agtaaattga tttccaatat atgttgagaa agattccata gctgggatat
     5821 ctcgactata agtacttcga gaagcaaatc cccattcctt agcaattccg tccatttgag
     5881 atgaagcatt taaactcatt tcaaccagta taaataaaga gattagaatg gcaaatagat
     5941 tcacagatat aaactttttg ataactgcaa ggagtaaaag agaatagaca accaaaaatt
     6001 caagagtaag cagaatattc aaatctgtta aaaaagaata atgcgatttt agatagatgg
     6061 tagctaaaaa tcctgttact acaagaaaaa gcgaaactaa aaaattccag actttaagtt
     6121 ctttcagacg ctttaagact tctgctgctg tgtaaattaa caaggtagag aaaatccaag
     6181 catagcgatg taaaaacatg tttggagtat gcatgccttg ccaaaataag tcaagagctt
     6241 ctatgtaaaa gcttgcaatt agaaatgcaa agaataatac atatatgagt ttcacgtgaa
     6301 acttaataga tttcagcgta aaaaataaaa tggtcaaaat aaaaggaagt agtccaacaa
     6361 aaatcattgg gatggcccca tactttgttg tgtcaaagga accaatgaat tgcttagcaa
     6421 agagatcaag ataccagcta ctttcagttt gaaactttgt aacttcagtc aatttttccc
     6481 catgtgtctg taaatcaaac agagtgggaa gagtcataat caaactagcc ataccagcta
     6541 aaaaggagat aactatgaaa tcaagaacag atgattttcg agtcttaaag tcccacgaaa
     6601 tttgacagag ataccagaaa ataagaaaca atactgtcat atatccaaaa taataatttt
     6661 gaataaataa gattgacaga cttgtaaagt acaataggag tttcttttca gttatcagta
     6721 gatgtaaacc agttataatt aaaggaatca agataaaaac atctagccag gtttttatct
     6781 ctaattgact gacagtgaaa ctcatcagag tataggaagt agataaggct agttttaaag
     6841 tctgagggat agattgaaac aatttattca aactaaaaaa ggttgacaga ccaatcaatc
     6901 caaattttaa gagagtggtc agataaacag catctggcat attcgttaga tcaaaaaagt
     6961 aaaccagagg tgagagaaaa ctacccaagt aataactaga cagagcatag aagtttagcc
     7021 ctagaccact tgtaaaggtg taaaacagac tactatttcc atgtaggata tttcgtaagg
     7081 ctacatcaaa aataacgtat tgatgaaagc catctcctaa tagaggagag ttgtcgctat
     7141 tccagtagat accttgagat agatatactc cagacataat cactacagga atgatgagag
     7201 aaataaaata ggttcgatat gtttttaaaa atgatttcat gttacctcgt agaatgatag
     7261 aaaactcagt tggttaaccc aactgagttt tgaagtttta tttagtcttt ccaaagttct
     7321 ttaacttttg cttgtacttc tgcattttct aggaattcat cgtaggtttc atcgatacgg
     7381 tcaatgacgc catttttaga taagacaatg atatggttag ccaaagtttg aataaattcg
     7441 tggtcatggc tagcaaagat gattgattct ttaaagtttt tcaatccatc attcaagctt
     7501 gagatagatt ccaagtccaa gtgatttgtt ggatcatcaa gtacaaggac atttgatttt
     7561 aagagcatga gttttgaaag catgacacga actttttctc cccctgacaa gacatttaca
     7621 ggtttgttaa cttcatctcc agagaagagc atacggccga ggaagccacg taggaaagta
     7681 ttgtcatctt cttctttact tgcgaattga cgcaaccagt caagaattga ttctcctcct
     7741 gcaaaatcag ctgagttatc ttttggtagg taagattgac tagttgtaac tccccacttg
     7801 acagttcctt catagtcaat atctcccatg attgcacgaa ttaatgcagt cgtttgaata
     7861 tcattttgtc caataagtgc tgtcttatca tctggacgca agatgaaact aatattatcc
     7921 aagatagttt caccatcaat ctttacagtt agattttcta ctgtcaagag atcattacca
     7981 atctcacgtt ccgctttaaa gttgataaat ggatatttac gactagatgg tacaatctct
     8041 tctagctcaa tcttatcaag cattttctta cgtgatgttg cctgccttga cttagaagca
     8101 ttggcagaga aacgagcaac gaattcttgc aattgtttaa ttttttcttc tgctttagca
     8161 ttacggtctg ctagcaattt agcagcaagc tcagaagatt ccttccagaa gtcgtagttt
     8221 ccgacataga gtttgatttt tccaaagtca aggtcggcca tgtgagtaca aactttgttt
     8281 aagaagtgac ggtcgtggga tactacgata actgtgttat caaagtcaat caagaagtct
     8341 tctaaccaag taatcgattg gatatccaaa ccgttagtag gctcgtccaa gagaagaaca
     8401 tctggtttac caaaaagtgc tttggcgagg agaaccttta ctttttcacc gttggccaat
     8461 tcgctcatgt tttggtagtg taattcttct ggaatgttta ggttttgaag tagttgagag
     8521 gcttcactct ctgcttccca acctccaagt tcggcaaact ctccttcgag ttcggcagca
     8581 cgaaccccgt cctcgtctga gaaatcttcc ttcatgtaga tagcatcttt ctctttcatg
     8641 atgctataaa gtttttcatt tcccatgata acgacatcaa tggcacgttc atcttcgtag
     8701 tcaaagtgat tttgacgaag aacagagaga cgttcatctg gaccaagaga gatgtgacca
     8761 gtagtaggtt cgatatctcc agctaaaatt tttaaaaagg ttgattttcc ggcaccatta
     8821 gcaccgatta atccgtaagt atttccttct gtaaatttga tattgacatc atcaaaaagt
     8881 ttgcgatcac taaaacgtag tgaaacatca gatactgtaa gcaatatttt tctcctatat
     8941 gtgtaatata tttattctac tagaaaatac agaaatattc aaatttttat ttgtcaattt
     9001 tgtgtaaatt atatttacag tatcctttac acaaatctgt aaaaagcaag gctgatttat
     9061 tttgataaat tacggttatt tcattaaaaa aatgctataa ttgaaaggac tatatcgaag
     9121 gagaacaaaa tgactaaacc cattatttta acaggagacc gtccaacagg aaaattgcat
     9181 attggacatt atgttggaag tctcaaaaat cgagtattat tacaggaaga ggataagtat
     9241 gatatgtttg tgttcttggc tgaccaacaa gccttgacag atcatgccaa agatcctcaa
     9301 accattgtag agtctatcgg aaatgtggct ttggattatc ttgcagttgg attggatcca
     9361 aataagtcaa ctatttttat tcaaagccag attccagagt tggctgagtt gtctatgtat
     9421 tatatgaatc tagtttcgtt agcacgtttg gagcgaaatc caacagtcaa gacagagatt
     9481 tctcagaaag gatttggaga aagcattccg acaggattct tggtctatcc aatcgctcaa
     9541 gcagctgata tcacagcttt caaggctaat tatgttcctg ttgggacaga tcagaaacca
     9601 atgattgagc aaactcgtga aattgttcgt tcttttaaca atgcatataa ctgtgatgtc
     9661 ttggtagagc cggaaggtat ttatccagaa aatgagagag cagggcgttt gcctggttta
     9721 gatggaaatg ctaaaatgtc taaatcacta aataatggta tttatttagc tgatgatgcg
     9781 gatactttgc gtaaaaaagt aatgagtatg tatacagatc cagatcatat ccgcgttgag
     9841 gatccaggta agattgaggg aaatatggtt ttccattatc tagatgtttt tggtcgtcca
     9901 gaagatgctc aagaaattgc tgatatgaaa gaacgttatc aacgaggtgg tcttggtgat
     9961 gtgaagacca agcgttatct acttgaaata ttagaacgtg aactgggtcc tattcgtgag
    10021 cgccgtattg aatttgctaa ggatatggga gaagtttata atatgattca aaaaggtagt
    10081 gaaagagcgc gtgaagttgc gggtcaaacc ctatctgagg taaaaggggc aatgggactt
    10141 cattacttta actaagttta ttttacaaga aactatcatt tctatctcga agaaaagata
    10201 gttttttatt tacccctgta acatttgaca aatttttata gaatggtatg atagatacaa
    10261 tataaaaaga gtcaagctca aaaagaaaga aaagaggaaa cttcgaatgt ctaattggga
    10321 cactaaattt ttgaaaaaag gttttacctt tgatgatgta ttgcttattc cagctgaaag
    10381 tcatgtgttg cctaacgatg cagatttaac aactaaattg gcagataatt tgactttaaa
    10441 tatcccaatt attaccgctg ccatggacac agttacagag agtcaaatgg ccattgctat
    10501 tgctcgtgca ggtggtctcg gagttatcca taaaaacatg tcaattgctc aacaagcaga
    10561 cgaggttcgt aaggtaaaac gttctgaaaa tggagttatt attgatccgt tcttcttgac
    10621 gcctgaacat acaattgctg aagcagatga gcttatgggt cgttaccgca tcagtggtgt
    10681 tccagttgtt gaaacacttg aaaatcgtaa attggttggt attttgacaa accgagatct
    10741 tcgttttatt tcagattata atcaaccaat ttcaaaccat atgactagtg aaaatcttgt
    10801 tactgctcct gtgggtacgg atcttgcaac ggctgagagt attcttcaag agcatcgtat
    10861 tgaaaaactt ccgttggtcg atgaagaagg cagtctttct ggtttgatca ctatcaaaga
    10921 tattgaaaaa gttattgagt ttccaaatgc ggctaaagat gaatttggtc gtcttctagt
    10981 tgcaggtgca gtaggtgtta cttcagatac atttgaacgt gcagaggctc tttttgaggc
    11041 aggagcggat gcgattgtta ttgatactgc acatggtcat tctgcaggtg tcttgcgtaa
    11101 aattgccgag attcgtgctc atttcccaga tcggactttg attgctggaa atattgctac
    11161 tgctgaaggt gcacgtgccc tttatgaagc gggtgtagac gttgttaagg ttggtattgg
    11221 accaggttct atctgtacta ctcgtgtgat tgctggtgtt ggtgttccgc aagtaacagc
    11281 tatctacgat gctgcagctg ttgcgcgcga atatggtaaa acgattattg ctgacggtgg
    11341 gatcaagtat tctggagata ttgtaaaagc acttgctgca ggtggaaatg ctgttatgct
    11401 tggatctatg tttgctggaa ctgatgaagc tccaggcgaa actgaaatct tccaaggacg
    11461 taaattcaag acttaccgtg gtatgggatc aattgctgct atgaagaaag gttcaagcga
    11521 ccgttatttc caaggttctg tcaatgaagc aaacaagctc gttccagaag gaattgaagg
    11581 tcgtgttgct tataaaggag cggcagctga tattgttttc caaatgattg gtggtattcg
    11641 ctctggtatg ggttactgtg gtgcagctaa ccttaaagaa ctacacgata atgctcaatt
    11701 tattgaaatg tctggtgctg gtttgaaaga aagccatcct catgatgtgc aaattactaa
    11761 tgaggcacca aattattcta tgtaaaaaac aatgaaaaga actccagtga aaacaggagt
    11821 tcttttacaa tgttgtcaat ttccatttac agaagcttta ccatcctgaa tagtgaagat
    11881 acttagattt tctggcagat tttgaagatg gtctaagctt gttgttgtga taaaggtttg
    11941 gattgattga gaaatcgttt ctaataattt taactgtcta gtgttgtcaa gttcactcat
    12001 cacatcgtca agcagtaata taggagattc tgtggtaatg ctttccatta attcgatttc
    12061 tgctaatttt atcgagagga cgagactacg atgttgacct tggcttccga aactagcatc
    12121 catcccattt atataaaaag aaatgtcatc tcgatgagga ccgacaccag tattcttttt
    12181 aaataaatct ctggatctac ttttttctaa agcaattttg aaagattcgg ataagttttg
    12241 tttgtcagtt atattgacag aagattgata ggatattgac aactcttcga tctgattaga
    12301 gagttcaaaa tgtttcttac gcccaaatga ttctagtttt tttatgaaat ctaagcggtg
    12361 attcattaca cgacatccat aatcaactag ctgatcatct aacacagaaa ggaatgtttc
    12421 atctattttt tgagctgatt ttaggtaagt gtttctttgc tttaggatgt ggttataatt
    12481 ggttaagtca gataaataga ttggcttaat ttgcccaagt tccatatcaa tgaattttcg
    12541 tcgaatcgaa ggtgctcctt taattagttg taaatcttca ggagcaaata agacaacatt
    12601 catgtgtcct acataatctg aaaggcgtgc ctgttttaag tgattaactt ttgttacacg
    12661 gcctttttgt gttagttcga tttctagggg aatggatcca gtttttttct gaacgagacc
    12721 tgaaagatga agttgttcct catcaaaatg aatgagattt ttatctgttc gagttcgatg
    12781 actacgcgtt aaggctaaaa aatagatagc ctctaacatg tttgtttttc cttgtgcatt
    12841 acgtcccaaa aagacattca atttaggatt aaagtctatt ttcgtttctt tgtaattacg
    12901 aaaagtcttg agagatagat gttgtagcca catgattatc taccagggaa tcgtggagct
    12961 tgttggcttt taggtgatga agcaggtttc gatttgtctt ttttaactcc cttattcatc
    13021 tttttgacaa gtttagcgat ccgttctttt tcaactttat cagcttggta ttcatcttgt
    13081 tcttcagaag taggttgtgt caacaagatg tcaatgttca tgtcagggat gtcaacttta
    13141 tcgccaatac gaagtttttt tccacgacga ctctctaatt ccctattaaa gtaaacagaa
    13201 tgttcagaga gaaatgattt aatagctcct ccgctatgtg taattccaag ttctttgagt
    13261 agtgcttgga gggtaataaa ttcttcaaat aatttgtatt ccataattca cctcaatctt
    13321 tggtattata ccatattttc ctaaaaatag tgagagagac agcgagaaat gtaagcgatt
    13381 tttatttcaa aagtgttaca gggaacaaga aaatttcagg ttttcgtgat ataatagaag
    13441 tctgtatata aggaggtaaa tcatggagtt agtgcatgga atttcaacac attttatcca
    13501 atcaaaaaag tttaaaacaa acaaaattac cgtgcgtttt accgctccat tatcccttga
    13561 tacgattgca ggtcacatgt tgagtgcaag tatgctagag actgctaatc agatgtaccc
    13621 cacttctcaa gatttgagga gacacttggc cagtctatac ggtacagata tgtcaaccaa
    13681 ttgtttcaga agagggcaaa gccacattat agaattgaca tttacctatg ttcgtgatga
    13741 gtttttaagt aggaaaaacg tgctaacctc tcagattttg gaacttgtaa aagaaactct
    13801 tttttcaccc gcagtagttg ataatgggtt tgatccggcc ttatttgaaa ttgagaaaaa
    13861 acaattgcta gcaagtttag cagctgatat ggatgattct ttttattttg cacataaaga
    13921 attggataaa ttgttttttc atgatgaacg tcttcaattg gaatatagtg atttacgaaa
    13981 tcgtatttta gctgaaactc cacaaagttc ttattcttgt ttccaagaat ttttagccaa
    14041 tgatcgaata gatttctttt tcctaggtga ttttaatgag gttgaaattc aaaatgtatt
    14101 agaatcattt ggctttaaag gtcgaaaagg agatgtgaag gttcagtatt gtcaacctta
    14161 ttctaatatc cttcaggaag gtatggttcg gaaaaatgtg ggacaatcca ttttggaatt
    14221 aggttatcat taccgttcta aatatggtga tgagcaacat ttacccatga ttgtaatgaa
    14281 tggtttactt ggtggatttg ctcactctaa gctctttaca aatgtccgtg aaaatgctgg
    14341 attagcttat accatttcaa gtgagcttga tttatttagt ggattcttga ggatgtatgc
    14401 tggtatcaat cgagaaaatc gtaaccaggc tcgtaaaatg atgaataatc aactgcttga
    14461 tttaaaaaaa ggttatttta cagagtttga gttaaatcag accaaggaaa tgattcgttg
    14521 gtcgttgtta ctttctcaag ataatcaatc ttcattgatt gaacgtgctt atcaaaatgc
    14581 cttatttgga aaatcttcag cagactttaa aagttggatt gcaaagcttg aacaaattga
    14641 caaagatgct atttgtagag tagctaataa tgtgaaacta caagcgattt actttatgga
    14701 aggaatagaa tgacaaaggt tgtttttgaa gaaaaatact atccagctgt aaaagaaaag
    14761 gtttatcgaa ctcgtttggc caacggattg acagttgctc ttttgcctaa aaaggaattt
    14821 aaagaggttt acgggagtgt cactgtacag tttggttcgg tagatacgtt tgtcacagaa
    14881 gttgacggat atgtaaaaca atatcctgga ggaattgctc attttcttga acataaatta
    14941 tttgagagag aagattctag tgatttgatg tcggctttta cgagtctagg tgcagatagt
    15001 aatgccttta caagctttac aaaaacaaac tatctttttt cagcaacgga ttatttttta
    15061 gaaaatttag atttacttga tgaattggta acatcagcac actttactga agcttccatt
    15121 ctgacagagc aggatattat tcagcaagaa cgagaaatgt accaagatga tccagattcg
    15181 tgtttattct tttcaacttt agcgaatttg tatcctggta cacctttagc aactgatata
    15241 gttggaagtg aggagtccat ttcccaaatc aatctaacta atttgcaaga aaattttaca
    15301 aagttttaca aacctgtaaa catgtctctg tttttagttg gtaattttga tgtggagcga
    15361 gtacaggact attttgaaag caaagaactg aaagattcag attttcagga agtagcaaga
    15421 gaaaagttgt ttttacagcc tgtaaagcca acagatagta tgagaatgga agtatcttct
    15481 cccaaactag cgattggagt tagaggtaag cgagaagttt ctgaagcgga ttgctatcga
    15541 catcatattt tattaaaatt attgtttgca atgatgtttg gttggacttc ggatcgtttt
    15601 caaaaatgtt atgaatcagg taaaattgat gcgtccttat ctctggaagt tgaaataaca
    15661 agtcgctttc attttgtcat gttgacaata gatacgaaag agccagttgc tttgtctcat
    15721 caatttagga aggctattcg taattttaca aaggatttag atattacaga ggaacattta
    15781 gatattatca aaagagagat gtttggcgaa tttttcagta gcatgaactc tcttgaattt
    15841 attgcaacgc aatatgatgc ttttgaaaat ggtgagacaa tttttgattt gccgaaaatt
    15901 ttacaggaaa ttactttaga ggatgtcctt gatgctggac atcatttaat agatgatggt
    15961 gacatagttg attttacaat attcccatcg tagtaaccta tcataataga cactagaaag
    16021 aagggatgac aagtatgaga aaaaaaacaa ttggagaggt tttacgatta gctagaatca
    16081 atcagggatt gagtttagat gaattgcaga aaaagacaga aatccagtta gatatgttgg
    16141 aagcaatgga agcagacgat ttcgatcaac ttccaagtcc tttttacacg cgttctttct
    16201 tgaaaaaata tgcatgggct gttgagttag atgaccaaat tgttttggat gcttatgatt
    16261 ctgggagtat gattacttat gaggaagtag atgttgatga agatgagttg acaggtcgta
    16321 gacgttcaag taagaaaaag aagaaaaaaa catcattttt acctttattt tattttatcc
    16381 tttttgcttt atcgatttta atttttgtga cttattatgt ttggaactat attcaaactc
    16441 aaccagagga gccttctctt tctaattaca gtgtggttca atcaacaagt tcaactagct
    16501 ctgttcccca ctcctcaagt agtagttctt ctagtataga atcagctata agtgtatcag
    16561 gcgaaggaaa tcatgtagaa atcgcttata agacaagtaa ggaaacagtt aaattgcaat
    16621 tggcagtttc agatgttaca agttgggtca gtgtttcaga aagcgaactt gagggcggtg
    16681 taaccttatc gccaaagaag aaaagtgcag aagcaacagt tgcaactaaa agtcctgtaa
    16741 caattacgtt aggtgttgta aaaggtgttg atttgacagt agataatcag actgttgatt
    16801 tatcgaaatt aacagctcag actggacaaa tcactgtaac ctttactaaa aattaaggaa
    16861 aaacgaatga aaaaagaaca aattcccaat ctcttaacaa taggtcgaat tctctttata
    16921 cctattttta tctttatttt gacgatagga aattcgatag agagtcatat agttgcagct
    16981 attatctttg ctgttgccag tattaccgac tatttagatg gatatttagc tcgtaaatgg
    17041 aatgtggtca gtaattttgg taaatttgca gatcctatgg cggataagtt actagttatg
    17101 tcggctttta ttatgttgat tgagttaggt atggctccgg cttggattgt tgcagtgatt
    17161 atctgtcgtg agttagctgt gacaggttta aggcttttat tggttgaaac tggtggaaca
    17221 attttagcag cagcaatgcc tggaaaaatt aaaactttta gtcagatgtt tgctattatt
    17281 ttcttgctat tacattggac tttgcttggt caagttctac tttatgtagc cttatttttc
    17341 actatctact ctggctatga ctatttcaag ggtagtgcct atgtatttaa agggacattt
    17401 ggttcgaaat gaaatcaata attgatgtaa aaaatctttc ttttcgctat aaagaaaatc
    17461 agaactacta cgatgtgaag gatattacgt ttcacgtgaa acgtggagaa tggctttcga
    17521 ttgtagggca taatggtagt ggtaaatcaa cgacggttcg attaattgat ggcttactgg
    17581 aagcagaatc cggagagatt gtaattgatg gccaacgttt gactgaggaa aatgtttgga
    17641 atatacgtcg tcaaatcggt atggtttttc aaaatccaga caatcaattt gttggagcga
    17701 ctgttgaaga tgatgttgct tttggtttgg aaaatcaggg actttctcgt caagaaatga
    17761 aaaagagagt ggaagaagct ctggctttag ttggcatgtt ggactttaaa aagagagagc
    17821 cagcgcgtct atcaggtggc caaaagcaac gtgtggccat tgcaggtgtt gtagccctaa
    17881 gaccagctat tttaatctta gatgaagcaa cgagtatgtt ggatcctgag gggcgtagag
    17941 aacttattgg gacagtaaaa ggaattcgaa aagactatga tatgacggtc atttctatta
    18001 cccatgattt ggaagaagtc gccatgagtg atcgcgtatt ggtcatgaaa aaaggggaaa
    18061 ttgaatcaac tagtagtcca agggagcttt tctctcgaaa tgatttagat caaattggat
    18121 tagacgatcc ttttgctaat caattaaaaa aatctttgag ccagaatggc tatgatttac
    18181 ctgaaaatta tttgacagaa agtgagctag aggataagct atgggaattg ctctagaaaa
    18241 tgtgaatttt atatatcaag aaggtactcc cttagcttca gcagctttgt cggatgtttc
    18301 tttgacgatt gaagatggct cttatacagc tttaattggg cacacaggta gtggtaaatc
    18361 aactatttta caactcttaa atggtttatt ggtgccaagt caagggagtg tgagggtttt
    18421 tgatacctta atcacctcga cttctaaaaa taaagatatt cgtcaaatta gaaaacaggt
    18481 tggcttggta tttcagtttg ctgaaaatca gatttttgaa gaaacggttt tgaaggacgt
    18541 tgcttttgga ccgcaaaatt ttggagtttc tgaagaagat gctgtgaaga ctgcgcgtga
    18601 gaaactggct ctggttggaa ttgatgaatc actttttgat cgtagtccgt ttgagctgtc
    18661 agggggacaa atgagacgtg ttgccattgc aggcatactt gccatggagc catctatatt
    18721 agtcttagat gagccaacag ctggtctaga tcctctaggg agaaaagagt tgatgaccct
    18781 gttcaaaaaa ctccaccagt cagggatgac catcgtcttg gtaacgcatt tgatggatga
    18841 tgttgctgaa tatgctaatc aagtctatgt aatggaaaag ggacgtttag taaagggggg
    18901 caaaccaagt gatgtctttc aagacgttgt ttttatggaa gaagttcagt tgggagtacc
    18961 taaaattacg gccttttgta aacgattggc tgatagaggc gtgtcattta aacgattacc
    19021 gattaagata gaggagttca aggagtcgct aaatggatag tatgattttg gggcgttata
    19081 tcccagggga ttcgattgtt caccgattgg atccacgtag caaattgctt gctatgatgc
    19141 tactgatttt gattgtgttt tgggctaata accccttgac gaatctgatt ctttttatag
    19201 cgacagggat atttattgcc ttgtcaggag tatctctttc attttttatt cagggcttga
    19261 agtctatgtt tttcttgatt gccttcacaa ctatttttca actatttttc atttctaatg
    19321 ggaatgtttt atttgagttt tcgtttgtga gaatcacgga ttatgctttg caacaagctg
    19381 ggattatttt ttgtcgcttt gtattgatta ttttcttttc aactttgtta accttaacaa
    19441 ccatgccttt aagtttggca tcagctgtcg aagctttatt agcaccttta aagcgtgtga
    19501 aagttccagt tcatgaaatt ggattgatgc tgtctatgag tttgcgtttt gtcccaacct
    19561 tgatggatga tacgactcgg attatgaatg cacagaaagc tcgtggagtg gattttggag
    19621 aaggaagcat cgttcaaaaa gtaaaggcga tgattcccat tttgattcct ctttttgcga
    19681 caagtttaaa acgtgcagat tccttggcta tcgctatgga agcgcgtggc tatcagggtg
    19741 gaaaaggcag aagtcaatac cgacaattga aatggactct aaaggatacg ctgaccattc
    19801 ttgttattct cgtacttggt tgttgtttat ttttcttaaa atcttagtag ctttcaggaa
    19861 ttgataaaaa gttactgtaa cagtttttga tataaaggta gggatatgaa ccgttttaaa
    19921 aaatcaaaat atgtcattat tgtttttgtc actgttctgc ttgtgtcagc tctcttagcg
    19981 acgacttatt caagtacaat tgtgacaaaa ttaggagatg gaatctcatt ggttgataga
    20041 gttgtacaaa aaccttttca gtggtttgat tctgtcaaat cagatttggc tcatttgaca
    20101 cgaacatata atgaaaatga aagtttgaag aaacagcttt accaattaga agttaaatca
    20161 aatgaggtgg aaagtttaaa gacagaaaat gaacaactgc gccaattgct tgatatgaag
    20221 tctaaattgc aagccacaaa gactttagca gcagatgtta ttatgcgttc tccggtatct
    20281 tggaagcagg agttgacctt agatgcaggt agatcaaaag gtgcttctga gaacatgtta
    20341 gctattgcaa atggtggctt gattgggagt gtttcaaaag tagaggagaa ctctactata
    20401 gtcaaccttc tgacaaatac ggaaaatgct gataagattt ctgttaaaat tcaacatggc
    20461 tctactacaa tttatggaat tattattggc tatgacaagg aaaatgacgt tcttaaaatt
    20521 agccaattaa atagtaatag cgatattagt gcgggagata aggtgactac tggtggatta
    20581 ggaaacttta acgttgctga tattcctgtt ggtgaagtgg ttgccacaac gcatagtaca
    20641 gactatttga cacgagaagt aactgttaaa ttgagtgcag atactcataa tgtagatgtg
    20701 atagaattag tggggaattc ataatgagac agttgaagcg agttggagta tttttattgc
    20761 ttcctttctt tgttctaatt gacgcccata ttagccagct tctgggctca tttttccccc
    20821 atgtacattt ggctagtcat tttctttttc tatttctctt atttgagacg atagaagtat
    20881 cagagtatct ctacctagtc tattgttttg ttataggctt ggtttatgat gtttactttt
    20941 tccatctaat agggattaca actctcttat ttatcttatt gggagccttc cttcataaat
    21001 tgaatagtgt tattttgttg aatcgttgga caagaatgct agctatgatt gtgctgacat
    21061 tcctgtttga aatgggtagt tatcttttgg cttttatggt agggttgaca gtagatagca
    21121 tgtcgatttt tatagtctat agcttggtac cgacgatgat tttaaatttt ttatggatta
    21181 ctgtttttca atttattttt gaaaaatatt atctataaga acgacatata aatgtaacaa
    21241 aggcgtaata tttattaggc ctttttttgg tatactagta ttgtctttaa aagaaggagt
    21301 atctacgtaa tatgaagaaa aaaatcttag cgtcactttt attaagtaca gtaatggttt
    21361 ctcaagtagc tgttttaaca actgcgcatg cagaaacgac tgatgacaaa attgctgctc
    21421 aagataataa aattagtaac ttaacagcac aacaacaaga agcccaaaaa caagttgacc
    21481 aaattcagga gcaagtatca gctattcaag ctgagcagtc taacttgcaa gctgaaaatg
    21541 atagattaca agcagaatct aagaaactcg agggtgagat tacagaactt tctaaaaaca
    21601 ttgtttctcg taaccaatcg ttggaaaaac aagctcgtag tgctcaaaca aatggagccg
    21661 taactagcta tatcaatacc attgtaaact caaaatcaat tacagaagct atttcacgtg
    21721 ttgctgcaat gagtgaaatc gtatctgcaa acaacaaaat gttagaacaa caaaaggcag
    21781 ataaaaaagc tatttctgaa aaacaagtag caaataatga tgctatcaat actgtaattg
    21841 ctaatcaaca aaaattggct gatgatgctc aagcattgac tacgaaacag gcagaactaa
    21901 aagctgctga attaagtctt gctgctgaga aagcgacagc tgaaggggaa aaagcaagtc
    21961 tattagagca aaaagcagca gctgaggcag aggctcgtgc agctgcggta gcagaagcag
    22021 cttataaaga aaaacgagct agccaacaac aatcagtact tgcttcagca aacactaact
    22081 taacagctca agtgcaagca gtatctgaat ctgcagcagc acctgtccgt gcaaaagttc
    22141 gtccaacata cagtacaaac gcttcaagtt atccaattgg agaatgtaca tggggagtaa
    22201 aaacattggc accttgggct ggagactact ggggtaatgg agcacagtgg gctacaagtg
    22261 cagcagcagc aggtttccgt acaggttcaa cacctcaagt tggagcaatt gcatgttgga
    22321 atgatggtgg atatggtcac gtagcggttg ttacagctgt tgaatcaaca acacgtatcc
    22381 aagtatcaga atcaaattat gcaggtaatc gtacaattgg aaatcaccgt ggatggttca
    22441 atccaacaac aacttctgaa ggttttgtta catatattta tgcagattaa tttacagagg
    22501 gactcgaata gagccctctt ttcaggtttt accgtgacaa tccctattaa aaattatatc
    22561 aaaatagctt gaaaatattg gaaaagtatg gtaaaatgaa aattgtcgtg tgaacgataa
    22621 tactcattct tgatgaattg tgaagcagtt gcccttgggt cgttttgcga gttgaagtca
    22681 agaagaggaa aaaaacaaaa aggagaaata ctcatggcag taatttcaat gaaacaactt
    22741 cttgaggctg gtgtacactt tggtcaccaa actcgtcgct ggaatcctaa gatggctaag
    22801 tacatcttta ctgaacgtaa cggaatccac gttatcgact tgcaacaaac tgtaaaatac
    22861 gctgaccaag catacgactt catgcgtgat gcagcagcta acgatgcagt tgtattgttc
    22921 gttggtacta agaaacaagc agctgatgca gttgctgaag aagcagtacg ttcaggtcaa
    22981 tacttcatca accaccgttg gttgggtgga actcttacaa actggggaac aatccaaaaa
    23041 cgtatcgctc gtttgaaaga aattaaacgt atggaagaag atggaacttt cgaagttctt
    23101 cctaagaaag aagttgcact tcttaacaaa caacgtgcgc gtcttgaaaa attcttgggt
    23161 ggtatcgaag atatgcctcg tatcccagat gtgatgtacg tagttgaccc acataaagag
    23221 caaatcgctg ttaaagaagc taaaaaattg ggaatcccag ttgtagcgat ggttgacacc
    23281 aatactgatc cagatgatat cgatgtaatc atcccagcta acgatgacgc tatccgtgct
    23341 gttaaattga tcacagctaa attggctgac gctattatcg aaggacgtca aggtgaggat
    23401 gcagtagcag ttgaagcaga atttgcagct tcagaaactc aagcagattc aattgaagaa
    23461 atcgttgaag ttgtagaagg tgacaacaaa tagtaattac ctaggagggc ggggcttagc
    23521 ccggctctcc tattttcaaa aaatatagga gaattaaaat ggcagaaatt acagctaaac
    23581 ttgtaaaaga gttgcgtgaa aaatctggtg ccggtgttat ggacgctaaa aaagcgcttg
    23641 tagaaacaga cggtgacatc gaaaaagcga ttgaattgct tcgtgaaaaa ggtatggcta
    23701 aggcagctaa gaaagctgac cgtgttgctg cagaaggttt gactggtgtt tatgttaacg
    23761 gtaatgttgc agcagttatt gaagtaaacg ctgaaactga cttcgttgca aaaaacgctc
    23821 aattcgttga attggtaaat actacagcta aagtcattgc tgaaggaaaa cctgctaata
    23881 atgaagaagc tcttgctttg ataatgcctt caggtgaaac tcttgaagct gcatacgtat
    23941 ctgcaacagc aactatcgga gagaaaatct cattccgtcg ctttgcattg attgaaaaaa
    24001 cagacgcaca acactttgga gcataccaac ataacggtgg acgtatcggt gttatttcag
    24061 ttgttgaagg tggagacgaa gcacttgcta aacaattgtc aatgcacatc gcagcgatga
    24121 aaccaacagt tctttcttac aaagaattgg atgagcaatt cgttaaagat gagttggcac
    24181 aattgaatca cgttatcgac caagacaacg aaagccgtgc aatggttaat aaaccagctc
    24241 ttccacactt gaagtatgga tcaaaagctc aattaactga tgatgttatt gctcaagctg
    24301 aagctgacat caaagctgaa ttggctgcag aaggcaaacc agaaaaaatc tgggacaaaa
    24361 ttatcccagg taaaatggat cgcttcatgc ttgataatac taaagttgac caagcttaca
    24421 cacttcttgc acaagtttac atcatggatg acagcaagac agttgaagca taccttgaat
    24481 cagttaacgc ttcggtagtt gagtttgctc gctttgaagt tggtgaaggt atcgagaaag
    24541 ctgcaaacga cttcgaagct gaagttgcag ctacaatggc agcagccttg aataactaat
    24601 aatagaaagg aagcaaattg cttccttttt tgtatagggc ttagattttt cctgaaattg
    24661 ttttttcccc agtctcactc gattagaata attaaaacaa aaagccctat aataagggct
    24721 aagtgcattt aggagactat acttcaaatt catagtaagc gcgtcataac aaggtatcta
    24781 tcctaattcc ccaacttcca gtataccaga taaaaaataa ttatcggagg aaaggtattg
    24841 tactatgata attcaactaa gtgatttagg tcaagttcac cttgtttgtg gcaagacaga
    24901 tatgaggcag ggaatagact cattagccta tgtagttaaa acccactttg aattggatcc
    24961 tttctccgat caagtctttc tcttttgtgg tggacgtaaa gaccgcttta aagttcttta
    25021 ctgggatggt caaggatttt ggatattata taaacgcttt gagaacggaa aactgacttg
    25081 gtccagtaca gaaaaggatg tcaaagctct cacatctgaa caagtagatt ggctgatgaa
    25141 gggcttttct atcactcccc aaatatagtg gatttaaact agaatagtac acctctgctt
    25201 ctaaaacatt gttagaaatc gatttgacta tcctgttctt atttcatttt actataaatt
    25261 catcagaaag tcgtgatttc tattgaaatg aggactttct ttttatactc atctgttttc
    25321 aaaaagcatt ctagtccgtc tccgattaac gatggacttt atcacctcct tctccagtcc
    25381 ttgtatgaca tcttccaaag ttcgaaaggc tttattctta aatccacgtt tacgaatctc
    25441 tttccacact tgttcaatgg ggttcatctc tggtgtgtat ggaggaataa atgcaaagcc
    25501 aatattagtc ggaatcttta aggtacttga tttatgccat atagcattgt ccataacgag
    25561 taaaagataa tcatctggat aagcttgtga aagctcctat tcctaaagcc cctttagcgc
    25621 ataactttgg ctcagcttct attatcgctc acaccatcca tcagaagttt aatctgaagg
    25681 tacccaatta tcgccaagaa gaagattggg ctaggatggg tttaccaatc acacgtaagg
    25741 aaatctctaa ttggcatatc aagacgagtc aatactattt ggagcccctt tataacctct
    25801 tgcgagagag actattgact cagcccttac ttcatgcgga tgaaacttct tatagggtgc
    25861 tagagagtga tagtcagctg acttactatt ggactttttt gtctgggaaa gctgagaaac
    25921 aagggattac gctttaccat catgttctaa tcgatttgtt catatcttat ttcaatccat
    25981 tataaatagt gagaaatatc tatcctatct tctagaatgt cttccaaacg tggaaactct
    26041 cgtaaacaaa gaggttttag aggcctattt accatggact aaagttgtac aagaaaagtg
    26101 caaataagaa atctccagat taggaactat ccgtgagttc tctagtctgg agatttttca
    26161 atagacttcg ttattggacg gttacaattc ataaagtgct gtagagagat aacgttcacc
    26221 gttatctggt gctagggcaa ggactttttt acctgtacct aattttttgg caacctcgat
    26281 ggctccgtag atagctgcag ctgaggaaat ccctacaagg aagccttctt ttccaccaat
    26341 ttcacgtccg agtgcaagag cgtcatctga tgttacacga acgataccat cataggcttt
    26401 agtatcaagt gtatcaggaa taaatccagc tgagatacct tgaattttgt gaggaccagg
    26461 tttttcacca gatagaatag cagattcatc tgcttctact gcaaaaactt gaatgttaga
    26521 attttctgat ttgagtgcat gagaaacacc agaaatcgtt ccaccagtac ctactccagc
    26581 aacaaaggca tctaatccat ctttaccgaa agcagctagt atctcagctc ctgttgttct
    26641 ttcgtgtact tctggattag ctggattgtc aaattgaaga ggaaggaaac catcacgttc
    26701 agcagcgatt tcttgagcct tagcaatagc acctttcatt ccctcgctac caggagttag
    26761 gacgagttca gcaccataag cttggataat tttacgtcgt tctacactca tagtttcagg
    26821 cataacgatg acgactttat accctttagc agcacctacc catgaaagtc caataccggt
    26881 gtttccactt gttgcttcaa caatagtaga accaggtttc agaataccat cttgttcagc
    26941 tttttcaatc atgctaaggg caatacggtc ttttacagat gaaccaggat taaatgcttc
    27001 aagctttata tagacgtctg cagcaccttc tggcacgatg ttgttaagtt taacaatcgg
    27061 tgtttgaccg attaattcag taatgttgtt ataaatagac atatgaatac ctctttgtat
    27121 aagatatctt tagtataacg ctatccatac catttgtaaa atatagaaat cctatcgaag
    27181 cgataggatt tctatatatc atagatcaaa gtcattaatt ttcaagtgat tgcgttcagc
    27241 taattctagt aaataggtgt gaaggaaaac gatatcaggt ttcgtttgaa ttgcttcatt
    27301 ttctagtata ttttggtacg catcttttta ttttgctcgc taaagtagtt gtgagaatgt
    27361 caacgaaacg ctgtattatt cattgtttac actaagttta caggaacttc aacctctcgt
    27421 aaaccttggt cagttaaagt gacttttcca ttaaaaaact ccacaagtgc agctttaata
    27481 gtttcttttt cttctttatc aacataaatc atcgtatcga cttgatctgt aaagtttgta
    27541 tccagctcca tgagaccatg ttctttaagg aagttactgt actcttggta ctgagcataa
    27601 gacatttgaa tagcaatgcc agcctgttct tttatttcaa taataccaat ttctttgaca
    27661 gctaaggcga cactgccggc gtaagcacga attagtcctc cagcgcctag tttaatacca
    27721 ccaaagtagc gtgtcacgac cacacagaca ttggtgagat tgtgattttc tagtacccca
    27781 agcatgggaa caccagcagt accactaggc tcaccatcat cacttgtacg tttaatttca
    27841 ctacgttctc caataatgaa ggcagagcag ttatgtgtcg ctttgtagtg ttcttttttg
    27901 atggcagtaa tgaagtcacg agcctcttct tcgctataaa cacgcttggc atggcagata
    27961 aagcgagatt ttttgatttc ttcttggact tgaccgtcct ctttaattgt cctaaattcc
    28021 atgatttaat tgtactaaaa aatcatctaa agtgctagtt tttacgaata aagaagtatg
    28081 aaagtaaatt tagattatct cggtcgttta tttactgaga atgaattaac agaagaagaa
    28141 cgtcagttgg cggagaaact tccagcaatg agaaaggaga aggggaaact tttctgtcaa
    28201 cgctgtaata gtactattct agaagaatgg tatttgccca tcggtgctta ctattgtcga
    28261 gagtgcttgc tgatgaagcg agtcagaagt gatcaaactt tatactattt tccgcaggag
    28321 gattttccaa agcaagatgt tctcaaatgg cgcggccaat taactccttt tcaagagaag
    28381 gtgtcagagg gattgcttca agtagtagac aagcaaaagc caaccttagt tcatgcggta
    28441 acaggagctg gaaagacaga aatgatttat caagtagtgg ctaaagtgat caatgcgggt
    28501 ggtgcagtgt gtttggctag tcctcgcata gatgtttgtt tggagctgta caagcgcctg
    28561 caacaggatt tttcttgcgg gatagctttg ctacatggag aatcggaacc ttattttcga
    28621 acaccactag ttgttgcaac aacccatcag ttattgaagt tttatcaagc ttttgatttg
    28681 ctgatagtgg atgaagtaga tgcttttcct tatgttgata atcccatgct ttaccacgct
    28741 gtcaagaata gtgtaaagga gaatggattg agaatctttt taacagcgac ttcgaccaat
    28801 gagttagata aaaaggtccg tttaggagaa ctaaaaagac tgaatttacc gagacggttt
    28861 catggaaatc cgttgattat tccaaaacca atttggttat cggattttaa tcgctactta
    28921 gacaagaatc gtttgtcacc aaagttaaag tcctatattg agaagcagag aaagacagct
    28981 tatccgttac tcatttttgc ttcagaaatt aagaaagggg agcagttagc agaaatctta
    29041 caggagcaat ttccaaatga gaaaattggc tttgtatctt ctgtaacaga ggatcgatta
    29101 gagcaagtac aagcttttcg agatggagaa ctgacaatac ttatcagtac gacaatcttg
    29161 gagcgcggag ttaccttccc ttgtgtggat gttttcgtag tagaggccaa tcatcgtttg
    29221 tttaccaagt ctagtttgat tcagattggt ggacgagttg gacgaagcat ggatagaccg
    29281 acaggagatt tgcttttctt ccatgatggg ttaaatgctt caatcaagaa ggcgattaag
    29341 gaaattcaga tgatgaataa ggaggctggt ctatgaagtg cttgttatgt gggcagacta
    29401 tgaagactgt tttaactttt agtagtctct tacttctgag gaatgatgac tcttgtcttt
    29461 gttcagactg tgattctact tttgaaagaa ttggggaaga gaactgtcca aattgtatga
    29521 aaacagagtt gtcaacaaag tgtcaagatt gtcaactttg gtgtaaagaa ggagttgaag
    29581 tcagtcatag agcgattttt acttacaatc aagctatgaa ggattttttc agtcgctata
    29641 agtttgatgg agacttcctg ttaagaaaag ttttcgcttc atttttaagt gaggagttga
    29701 aaaagtacaa agagtatcaa tttgttgtaa ttcccctaag tcctgataga tatgctaata
    29761 gaggatttaa tcaggttgag ggcttggtag aggcagcagg ctttgagtat ctggatttat
    29821 tagagaaaag agaagagaga gccagttctt ctaaaaatcg ttcagagcgc ttggggacag
    29881 aacttccttt ctttattaaa agtggagtca ctattcctaa aaaaatccta cttatagatg
    29941 atatctatac tacaggagca actataaatc gtgttaagaa actgttggaa gaagctggtg
    30001 ctaaggatgt aaaaacattt tcccttgtaa gatgaggaaa aaatttgcaa aaatagaatg
    30061 aaagcgttat aataaaatca taaaaacaaa aatgtttaga aagaaggtac tcatatgatt
    30121 aaatatagta tccgtggtga aaacctagaa gtaacagaag caattcgtga ttatgtagtt
    30181 tctaaactcg aaaagatcga aaagtacttc caaccagaac aagagttgga tgcccgaatt
    30241 aacttaaaag tttatcgtga aaaaacggct aaagtggaag taacgattcc gcttggatct
    30301 attactctcc gcgcagaaga tgtatctcaa gatatgtatg gttcaattga ccttgtaact
    30361 gataaaattg aacgtcagat tcgtaaaaat aaaacaaaaa tcgagcgtaa aaataaaaat
    30421 aaggtagcaa ctggtcaatt atttacagat gctttggtgg aagattcaaa tgttgtccag
    30481 tctaaagttg ttcgttcaaa acaaattgat ttaaaaccaa tggatttgga agaagcaatt
    30541 ctacaaatgg atttattggg gcatgatttc tttatctatg tggatgttga agatcagaca
    30601 accaatgtga tttatcgtcg tgaggatggc gaaattggtt tgttagaggt taaagaatct
    30661 taatttcaat atgtgtaaag gtaggtttac tgaattgtaa actacctttt tcttataatt
    30721 gatagaatta ctgattacac ttttaaaaag tcgctttttg aggggtatta tggtataatg
    30781 ggtgccaaga ggttttgaat gaaaaaattt tatgtaagtc caatttttcc tattctagta
    30841 ggattgattg cgtttggagt cttatccact ttcattattt ttgttaataa taatctgttg
    30901 acggttttaa ttttgtttct ttttgtagga ggctatgttt ttttatttaa gaaactgaga
    30961 gtgcattata caaggagtga tgtagaacag atacagtatg taaaccacca agcggaagaa
    31021 agtttgacat ctctattgga acaaatgcct gtaggtgtta tgaaattgaa tttatcttct
    31081 ggagaggttg agtggtttaa tccctatgct gaattgattt tgaccaagga agatggtgat
    31141 tttgatttag aagctgttca aacgattatc aaggcttcag taggaaatcc gtctacttat
    31201 gccaagcttg gtgagaagcg ttatgctgtt catatggatg cttcttccgg tgttttgtat
    31261 tttgtagatg tatccaggga acaagccata acagatgaat tggtaacaag tcgaccagtg
    31321 attgggattg tctctgtgga taattatgat gatttggagg atgcaacttc tgagtcagat
    31381 attagtcaaa tcaatagttt tgtagctaat tttatatcag agttttcaga aaaatacatg
    31441 atgttttctc gtcgggtaag tatggatcga ttttatctat ttactgacta cacggtgctt
    31501 gagggcttga tgaatgataa attttctgtt attgatgctt tcagagaaga gtcgaaacag
    31561 agacagttgc ccttgacctt aagtatggga ttttcttatg gcgatggaaa tcatgatgag
    31621 atagggaaag ttgctttgct caatttgaac ttggctgaag tacgtggtgg cgaccaggtg
    31681 gttgttaagg aaaacgacga aacgaaaaat ccagtttatt ttggtggtgg gtctgctgct
    31741 tcaatcaagc gtacacggac tcgtacgcgc gctatgatga cagctatttc agataagatt
    31801 cggagtgtag atcaggtttt tgtagtcggt cacaaaaatt tagacatgga tgctttgggc
    31861 tctgctgtag gtatgcagtt gttcgccagc aatgtgattg aaaatagcta tgctctttat
    31921 gatgaagaac aaatgtctcc agatattgaa cgagctgttt cattcataga aaaagaagga
    31981 gttacgaagt tgttgtctgt taaggatgca atggggatgg tgaccaatcg ttctttgttg
    32041 attcttgtag accattcaaa gacagcctta acattatcaa aagaatttta tgatttattt
    32101 acccaaacca ttgttattga ccaccataga agggatcagg attttccaga taatgcggtt
    32161 attacttata tcgaaagtgg tgcaagtagt gccagtgagt tggtaacgga attgattcag
    32221 ttccagaatt ctaagaaaaa tcgtttgagt cgtatgcaag caagtgtctt gatggctggt
    32281 atgatgttgg atactaaaaa tttcacctcg cgagtaacta gtcggacatt tgatgttgct
    32341 agctatctca gaacgcgcgg aagtgatagt attgctatcc aggaaatcgc tgcgacagat
    32401 tttgaagaat atcgtgaggt caatgaactt attttacagg ggcgtaaatt aggttcagat
    32461 gtactaatag cagaggctaa ggacacgaaa tgctatgata cagttgttat tagtaaggca
    32521 gcagatgcca tgttagccat gtcaggtatt gaagcgagtt ttgttcttgc gaagaataca
    32581 caaggattta tctctatctc agctcgaagt cgtagtaaac tgaatgtaca acggattatg
    32641 gaagagttag gcggtggagg ccactttaat ttggcagcag ctcaaattaa agatgtaacc
    32701 ttgtcagaag caggtgaaaa actgacagaa attgtattaa atgaaataaa ggaaaaggag
    32761 aaagaagaat gaaagtaatc tttttagcag atgttaaagg aaaaggtaaa aaaggcgaaa
    32821 ttaaggaagt accaacaggg tatgcgcaaa actttcttat caaaaagaat ctagccaaag
    32881 aagcgactgc tcaagctgta ggtgaacttc gtggtaaaca aaaatcggaa gaaaaagctc
    32941 acgctgagat gattgcagaa ggaaaagcaa ttaaagcaca acttgaagca gaagaaactg
    33001 ttgtagaatt tgttgaaaaa gttggtccag atggtcgtac ctttggttct attaccaata
    33061 agaagattgc agaagaattg caaaagcaat ttggaattaa gattgataaa cgtcatattc
    33121 aagtacaagc tccgattcga gcggttggtt tgattgatgt gccagtgaaa atctatcaag
    33181 atatcacaag tgtaatcaat cttcgtgtga aagaaggata agtttacacc ttcttgacaa
    33241 gattgtaaaa ggaagggaag tctgatggca gaagtagaag agttacgagt acaacctcaa
    33301 gatatcttag ctgagcaatc cgttttaggg gctatcttta ttgatgagag taaacttgtt
    33361 tttgtgcgag aatacattga gtctcgggac ttttttaagt atgcccatcg tttgattttc
    33421 caagccatgg tcgatttatc cgatcgtggt gatgccatag atgcaacaac ggttcgtact
    33481 atccttgata atcaaggtga tttacagaat attggtggct tgtcttactt ggttgagatt
    33541 gttaattctg tgccaacttc tgctaatgcg gagtattatg ctaagattgt tgcagaaaaa
    33601 gcaatgctac gtcgtttaat tgccaagttg acagagtctg tcaaccaagc ttacgaagcg
    33661 tcacaaccag ctgatgaaat tattgctcag gcagaaaaag ggttgattga tgtcagtgaa
    33721 aatgcaaatc gaagcgggtt taagaacatt cgagatgtgt tgaatctcaa ctttggaaat
    33781 ctggaagctc gctcgcaaca aacgaccgat attacaggta ttgcgacagg ttatcgtgat
    33841 ttggatcata tgacaacagg acttcatgag gaggagttga ttatcttagc agctcgtcca
    33901 gcagttggta agacagcatt tgccttgaat atcgctcaga atattgggac taagttggac
    33961 aaaacggttg ctattttttc actcgaaatg ggtgcggaaa gcttggtaga ccgtatgtta
    34021 gctgcagaag gcttggtgga gtcacattct atccgtacag ggcaattgac agatgaggag
    34081 tggcaaaaat atactattgc tcagggtaat ctagctaacg ccagtatcta tatcgatgat
    34141 acgccaggta ttcggattac agagattcgt tctcgttctc gtaaattggc tcaagaaact
    34201 ggaaatcttg gtttgatttt gatagactat ttgcaactta tcacgggaac tggtcgagaa
    34261 aatcgtcaac aagaagtttc tgaaatttct cgtcagttga aaatactagc caaggaattg
    34321 aaggttccag taatcgctct gagtcagctt tctcgtggtg tagaacaacg tcaggacaag
    34381 agaccggtct tgtctgatat tcgtgaatct gggtctattg agcaggacgc tgatatcgta
    34441 gcttttctct atcgcgatga ctactatgaa cgtggtggtg aagaagagga gggtatccca
    34501 aataataagg tggaagttat tatcgagaaa aaccgtagtg gagctcgtgg aacagtggaa
    34561 ttgattttcc aaaaagaata caataaattt tcaagtatct caaagaggga ggcataagat
    34621 gtcagatgca tttacagatg tagccaagat gaaaaaaatc aaagaagaaa tcaaggcaca
    34681 tgagggacaa gtcgtagaaa tgactttgga gaatggtcgt aagcgccaaa aaaatagatt
    34741 gggtaagcta attgaagttt atccatccct atttattgtg gagtttgggg atgtggaagg
    34801 agataaacaa gttaatgttt acgttgaatc ctttacttac tcagatattc ttacagaaaa
    34861 gaatttgatt cattatcttg actaaagtga gaaattttct cactttttct tttttctccg
    34921 aataatttag gtgaaggcaa tcatcgcttt atattatttt ttaaggagga agaatgaaaa
    34981 ttttaccgtt tatagcaaga ggaacaagtt attacttgaa gatgtcagtt aaaaagcttg
    35041 ttcctttttt agtagtagga ttgatgctag cagctggtga tagtgtctat gcctattcca
    35101 gaggaaatgg atcgattgcg cgtggggatg attatcctgc ttattataaa aatgggagcc
    35161 aggagattga tcagtggcgc atgtattctc gtcagtgtac ttcttttgta gcctttcgtt
    35221 tgagtaatgt caatggtttt gaaattccgg cagcttatgg aaatgcgaat gaatggggac
    35281 atcgtgctcg tcgggaaggt tatcgtgtag ataatacacc gacgattggt tccattactt
    35341 ggtctactgc aggaacttat ggtcatgttg cctgggtgtc aaatgtaatg ggagatcaga
    35401 ttgagattga ggaatataac tatggttata cagaatccta taataaacga attataaaag
    35461 caaacacgat gacaggattt attcatttta aagatttgga tggtggcagt gttgggaata
    35521 gtcaatcctc aacttcaaca ggcggaactc attattttaa gaccaagtct gctattaaaa
    35581 ctgaacccct agttagtgca actgtgattg attactatta tcctggagag aaggttcatt
    35641 atgatcaaat tctcgaaaaa gacggctaca agtggttgag ttatactgcc tataatggaa
    35701 gctatcgtta tgttcaattg gaggctgtga ataaaaatcc tctaggtaat tctgttcttt
    35761 cttcaacagg tggaactcat tattttaaga ccaagtctgc tatcaaaact gaacccctag
    35821 ttagtgcaac tgtgattgat tactattatc ctggggagaa ggttcattat gatcagatac
    35881 ttgaaaaaga cggctacaag tggttgagtt atacggctta taacggaagt cgtcgctata
    35941 tacagctaga gggagtgact tcttcacaaa attatcagaa tcaatcagga aatatctcta
    36001 gctatggatc caataatagt tcaactgtcg gttggaagaa aataaatggt agttggtatc
    36061 atttcaaatc aaatggttct aaatcaacag gatggctgaa agatggttct agctggtatt
    36121 atttgaaatt atctggtgaa atgcagacag gatggttaaa ggagaatggc tcgtggtatt
    36181 atctgggtag ttcaggggca atgaaaacag gctggtacca ggtctctggt aagtggtatt
    36241 attcttactc ttcaggcgcc ttagctgtta atacgacggt ggatggctac agagtaaaca
    36301 gtgatggaga acgagtatag aaaattggag taggagaaat ttcctgctct tttctgtaag
    36361 cagtttcctt gacatttttc ttattttgcg ctatcatata tacatataat atatgggagt
    36421 ctgtgtacag tctgagagga agtgttaaac ttcgaccgca cctgatctgg gtaatgccag
    36481 cggagggaac gatacttagt ctaattttgc accttttcca tgtatggtaa aggtttttct
    36541 ttttttaaaa aggaaaacga gaagaggagg ttcttatgaa agcaagcatt gccttgcaag
    36601 ttttacccct agcacagggg attgatcgga tagctgttat tgatcaggtc attgcttatc
    36661 tgcaaactca agaagtgacg atggtagtga caccatttga aacggtcttg gaaggggagt
    36721 ttgatgagct tatgcgcatt ctaaaagaag cgctggaagt ggcagggcag ggggcagaca
    36781 atgtcttttc caatgtcaaa ataaatgtag gagagatttt aagtattgat gagaaacttg
    36841 agaagtatac tgagacgaca cattagtcta ttgggctttc tcggagtctt gtcaatctgg
    36901 cagttagcag gttttcttaa acttctcccc aagtttatcc tgccgacacc tcttgaaatt
    36961 ctccagccct ttgttcgtga cagagaattt ctctggcacc atagctgggc gaccttgaga
    37021 gtggctttac tggggctgat tttgggagtt ttgattgcct gtcttatggc tgtactcatg
    37081 gatagtttga cttggttcaa tgacctgatt taccctatga tggtggtcat tcagaccatt
    37141 ccgaccattg ccatagctcc tatcctggtc ttgtggctag gttatgggat tttgcccaag
    37201 attgtcttga ttatcttaac aacaaccttt cccatcatcg ttagtatttt ggacggtttt
    37261 aggcattgtg acaaggatat gctgaccttg tttagtctga tgcgagcaaa cccttggcaa
    37321 atcctgtggc attttaaaat cccggttagc ctgccttact tttatgcagg tctgagggtc
    37381 agtgtctcct acgcctttat cacaactgtg gtatctgagt ggttgggagg ttttgagggg
    37441 cttggtgttt atatgattca gtccaagaaa ttgtttcagt atgataccat gtttgccatt
    37501 attattctgg tgtcgattat cagtcttttg ggtatgaagc tggtcgatat cagtgaaaaa
    37561 tatgtgatta aatggaaacg tacttaaaat agagcgtttt tgaaaaagaa aagaggaaat
    37621 caaaatgaag aaaacatgga aagtgttttt aacgcttgta acagctcttg tagctgttgt
    37681 gcttgtggcc tgtggtcaag gaactgcttc taaagacaac aaagaggcag aacttaagaa
    37741 ggttgacttt atcctagact ggacaccaaa taccaaccac acagggcttt atgttgccaa
    37801 ggaaaaaggt tatttcaaag aagctggagt ggatgttgat ttgaaattgc caccagaaga
    37861 aagttcttct gacttggtta tcaacggaaa ggcaccattt gcagtgtatt tccaagacta
    37921 catggctaag aaattggaaa aaggagcagg aatcactgcc gttgcagcta ttgttgaaca
    37981 caatacatca ggaatcatct ctcgtaaatc tgataatgta agcagtccaa aagacttggt
    38041 tggtaagaaa tatgggacat ggaatgaccc aactgaactt gctatgttga aaaccttggt
    38101 agaatctcaa ggtggagact ttgagaaggt tgaaaaagta ccaaataacg actcaaactc
    38161 aatcacaccg attgccaatg gcgtctttga tactgcttgg atttactacg gttgggatgg
    38221 tatccttgct aaatctcaag gtgtagatgc taacttcatg tacttgaaag actatgtcaa
    38281 ggagtttgac tactattcac cagttatcat cgcaaacaac gactatctga aagataacaa
    38341 agaagaagct cgcaaagtca tccaagccat caaaaaaggc taccaatatg ctatggaaca
    38401 tccagaagaa gctgcagata ttctcatcaa gaatgcacct gaactcaagg aaaaacgtga
    38461 ctttgtcatc gaatctcaaa aatacttgtc aaaagaatac gcaagcgaca aggaaaaatg
    38521 gggtcaattt gacgcagctc gctggaatgc tttctacaaa tgggataaag aaaatggtat
    38581 ccttaaagaa gacttgacag acaaaggctt caccaatgaa tttgtgaaat aatgacagaa
    38641 attagactag agcacgtcag ttatgcctat ggtcaggaga ggattttaga ggatatcaac
    38701 ctacaggtga cttcaggcga agtggtttcc atcctaggcc caagtggtgt tggaaagacc
    38761 accctcttta atctaatcgc tgggatttta gaagttcagt cagggagaat tgtccttgat
    38821 ggtgaagaaa atccccaggg gcgcgtgagt tatatgttgc aaaaggatct gctcttggag
    38881 cacaagacgg tgcttggaaa tatcattctg cccctcttga ttcaaaaggt ggataaggca
    38941 gaagctattt cccgagcgga taaaattctt gcgaccttcc agctgacagc tgtaagagac
    39001 aagtatcctc atgaacttag cggtgggatg cgccagcgtg tagccttact ccggacctac
    39061 ctttttgggc acaagctctt tctcttagat gaggccttta gcgccttgga tgagatgaca
    39121 aagatggaac tccacgcttg gtaccttgag attcacaagc agttgcagct aacaaccttg
    39181 attattactc acagtatcga ggaggccctc aatctcagtg accgcatcta tatcttgaaa
    39241 aatcgccctg ggcagattgt ttcagaaatt aaactagatt ggtctgaaga tgaggacaag
    39301 gaagttcaaa agattgccta caaacgtcaa atcttggcag aattaggctt agataagtag
    39361 aaaaataggg agttggtgaa gattatcctt taccagcgcc ctttttcttt taaaaatgag
    39421 aaaatttcgg tataatagtc aaacaaggtc aaggtttaaa gagagaggtg ggtttgttat
    39481 gagatttaaa aatacatcgg atcatattga ggcctacatc aaggcgattt tagatcaatc
    39541 tggtatcgtg gagttgcaac ggagtcagtt ggcagatacc tttcaggttg ttcctagtca
    39601 gattaactac gtgatcaaga cacgctttac ggaaagtaga ggctacttgg ttgaaagtaa
    39661 gcgtggtggc ggaggctaca ttcgtatagg acggattgag ttttctagtc atcatgaaat
    39721 gctccgggag ctgctttact cgattggtga gcgagtcagt caagaaattt atgaggatat
    39781 tctccagctt ttggttgagc aggaattgat gaccaagcag gagatgaatt tgctagaatc
    39841 agtagctttg gatcgcgttt taggagaaga agctccagtt gttcgagcaa acatgctacg
    39901 tcagatcata caagaggtag atagaaaagg gaagtaagat gaactattca aaagcattga
    39961 atgaatgtat cgaaagtgcc tacatggttg ctggacattt tggagctcgt tatctagagt
    40021 cgtggcactt gttgattgcc atgtctaatc acagttatag tgtagcaggg gcaactttaa
    40081 atgattatcc gtatgagatg gaccgtttag aagaggtggc tttggaactg actgaaacgg
    40141 actatagcca ggatgaaacc tttacggaat tgccgttctc ccgtcgtttg caggttcttt
    40201 ttgacgaagc agagtatgta gcgtcagtgg tccatgctaa ggtgctaggg acagagcacg
    40261 tcttctatgc gattttgcat gatggcaatg ccttggcaac tcgtatcttg gagagggctg
    40321 gtttttctta tgaagacaag aaagatcagg tcaagattgc tacccttcgt cgaaatttag
    40381 aagaacgtgc aggctggact cgtgaagatc tcaaggcttt acgccaacgc catcgtacag
    40441 tagctgacaa gcaaaattct atggccaata tgatgggcat gccgcagact cctagtggtg
    40501 gtctcgagga ctatacgcat gatttgacag agcaagcgcg ttctggcaag ttagaaccag
    40561 tcatcggtcg ggacaaggaa atctcacgta tgattcaaat attgagccgt aagactaaga
    40621 acaaccctgt cttggttggg gatgctggtg tcgggaaaac agctctggcc cttggtcttg
    40681 ctcagcgtat tgctagtggt gacgtgcctg cggaaatggc taagatgcgc gtgttagaac
    40741 ttgatttgat gaatgtcgtt gcagggacac gcttccgtgg tgactttgaa gaacgcatga
    40801 ataatatcat caaggatatt gaagaagatg gccaagtcat cctctttatc gatgaactcc
    40861 acaccatcat gggttctggt agcgggattg attcgactct ggatgcggcc aatatcttga
    40921 aaccagcctt ggcgcgtgga actttgagaa cggttggtgc caccactcag gaagaatatc
    40981 aaaaacatat cgaaaaagat gcggctcttt ctcgtcgttt cgctaaagtg acgattgaag
    41041 aaccaagtgt ggcagatagt atgactattt tacaaggttt gaaggcgact tatgagaaac
    41101 atcaccgtgt acaaatcaca gatgaagcgg ttgaaacagc ggttaagatg gctcatcgtt
    41161 atttaaccag tcgtcacttg ccagactctg ctatcgacct cttggacgaa gcagcagcaa
    41221 cagtgcaaaa taaggcaaag tatgtaaaag cagacgattc agatttgagt ccagctgaca
    41281 aggccctgat ggatggcaag tggaaacagg cagcccagct aatcgcaaaa gaagaggaag
    41341 tacctgtcta caaagacttg gtgacagagt ctgatatttt gaccaccttg agtcgcttgt
    41401 caggaatccc agttcaaaaa ctgactcaga ctgacgctaa gaaatatcta aatcttgaag
    41461 cagaactcca taaacgggtt atcggtcaag atcaagctgt ttcaagtatt agtcgtgcga
    41521 ttcgccgtaa tcagtcagga attcgcagtc acaagcgtcc gatcggttcc tttatgttcc
    41581 taggacccac aggtgtcggt aagaccgagt tggccaaggc tttggcagaa gttctctttg
    41641 atgacgaatc agcccttatc cgctttgata tgagtgagta tatggagaaa ttcgcagcca
    41701 gccgtctaaa tggagctcct ccaggctatg tgggttacga agaaggtggg gagttgacag
    41761 agaaggttcg caataaaccc tattccgttc tcctctttga tgaggtagag aaggctcacc
    41821 cagatatctt taatgttctc ttgcaggttc tggatgacgg tgtcttgaca gatagcaagg
    41881 gacgcaaggt cgatttttca aataccatta tcattatgac atcgaaccta ggtgcgactg
    41941 cccttcgtga tgataagact gttggttttg gggctaagga tattcgtttt gaccaggaaa
    42001 atatggaaaa acgcatgttt gaagaactga aaaaagctta tagaccggaa ttcatcaacc
    42061 gtattgatga gaaggtggtc ttccatagcc tatctagtga ccatatgcag gaagtggtga
    42121 agattatggt caagccttta gtggcaagtt tggctgaaaa aggcattgac ttgaaattac
    42181 aagcttcagc tctgaaattg ttagcaaatc aaggatatga cccagagatg ggagctcgcc
    42241 cacttcgcag aaccctgcaa acagaagtgg aggacaagtt ggcagaactt cttctcaagg
    42301 gagatttagt ggcaggcagc acacttaaga ttggtgtcaa agcaggccag ttaaaatttg
    42361 atattgcata aaagaataaa agtaccagca tctgaccata agtcacagtg gagtgaaact
    42421 caatgaaaat caaagagcaa actaggcagc tagccgcagg ttgctcaaaa cactggtttg
    42481 aggttgcaga tagagctgac gtggtttgaa gagattttcg aagagtataa gctgcaagat
    42541 gaatgatttt cttgtattga cgttgttgtt gacaaaaagt agcggataaa tgaaatccat
    42601 tccattatca tagatgatag gctggtagga aattttcaaa tagcatacag gaaatagatg
    42661 tatggagttc tggtagtaga aagggagaga gatgaacatt ttagttgcag atgacgagga
    42721 aatgattaga gaaggaattg cagcatttct gacagaagag ggttatcatg tcattatggc
    42781 taaggatgga caagaggtct tggaaaaatt tcaagatctc cctatccatc tcatggtact
    42841 ggatttaatg atgcctagga agagtggttt tgaagtgtta aaagaaatca atcaaaagca
    42901 cgatattcct gtcatcgtct tgagtgctct gggagatgaa actactcagt cacaggtatt
    42961 tgatctctat gctgatgatc atgtgacaaa acctttttct ttggtactgc ttgtcaagcg
    43021 tattaaggcg cttatcagac gttactacgt catagaggat ctttggcgat atcaggatgt
    43081 aacagtggat tttacctctt acaaagcaca ttataaaaat gaagaaattg atctcaaacc
    43141 aaaggaatta ctggtactaa agtgtttgat tcagcataaa aatcaagttt taagtagaga
    43201 gcagatattg gaagaaattt caaaagatgt agctgattta ccttgtgata gggtcgttga
    43261 tgtctatatt cgtactcttc gcaaaaaatt agctttagat tgtatcgtga ctgtgaaaaa
    43321 tgttgggtat aagattagct tatgataaaa aatcctaaat tattaaccaa gtctttttta
    43381 agaagttttg caattctagg tggtgttggt ctagtcattc atatagctat ttatttgacc
    43441 tttccttttt attatattca actggagggg gaaaagttta atgagagcgc aagagtgttt
    43501 acggagtatt taaagactaa gacatctgat gaaattccaa gcttactcca gtcttattca
    43561 aagtccttga ccatatctgc tcaccttaaa agagatattg tagataagcg gctccctctt
    43621 gtgcatgact tggatattaa agatggaaag ctatcaaatt atatcgtgat gttagatatg
    43681 tctgttagta cagcagatgg taaacaggta accgtgcaat ttgttcacgg ggtggatgtc
    43741 tacaaagaag caaagaatat tttgcttttg tatctcccat atacattttt ggttacaatt
    43801 gctttttcct ttgttttttc ttatttttat actaaacgct tgctcaatcc tcttttttac
    43861 atttcagaag tgactagtaa aatgcaagat ttggatgaca atattcgttt tgatgaaagt
    43921 aggaaagatg aagttggtga agttggaaaa cagattaatg gtatgtatga gcacttgttg
    43981 aaggttattc atgagttgga aagtcgtaat gagcaaattg taaaattgca aaatcaaaag
    44041 gtttcctttg tccgcggagc atcacatgag ttgaaaaccc ctttagccag tcttagaatt
    44101 atcctagaga atatgcagca taatattgga gattacaaag atcatccaaa atatattgca
    44161 aagagtataa ataagattga ccagatgagc cacttattgg aagaagtact ggagtcttct
    44221 aaattccaag agtggacaga gtgtcgtgag accttgactg ttaagccagt tttagtagat
    44281 attttatcac gttatcaaga attagctcat tcaataggtg ttacaattga aaatcaattg
    44341 acagatgcta ccagggtcgt catgagtctt agggcattgg ataaggtttt gacaaacctg
    44401 attagtaatg caattaaata ttcagataaa aatgggcgtg taatcatatc cgagcaagat
    44461 ggctatctct ctatcaaaaa tacatgtgcg cctctaagtg accaagaact agaacattta
    44521 tttgatatat tctatcattc tcaaatcgtg acagataagg atgaaagttc cggtttgggt
    44581 ctttacattg tgaataatat tttagaaagc tatcaaatgg attatagttt tctcccttat
    44641 gaacacggta tggaatttaa gattagcttg tagacagatt agttttttat taaagttcac
    44701 atagggttaa cataagtgta ttattcttta tatagataaa aatatagata aaagaaagga
    44761 tactaatatg gtattagcga ttattttagt aatattcctt attcgattga tttttttaaa
    44821 gcgttcgata gagaatgaga aacgaatcct tagcaatggc gggaaagaat ttggagttga
    44881 gaatacaaaa cgattaacgt tggctcatat tgttttttat ctctcttgcc tcgttgaagc
    44941 aatggtgcat aagacaatgt ttgatggtat gagcatggtt ggtttagtct tgcttatttt
    45001 ttctatgctg atgttgatgt tggtgattca cttgttggga gatatttgga cagtgaagct
    45061 tatgcttgtc aataatcaca aatatgtaga tcatatcttg tttaggacag taaaacaccc
    45121 taattacttt ttaaatattc ttcctgagtt gattggcttg accttgttga gtcatgctta
    45181 tgtgactttt gttttagttt ttccagttta tgcagttatt ttgtatcgac gaatagctga
    45241 agaggaaaag ctattacatg aagttataat cccaaatgga agcataaaga gataaataca
    45301 aaattcgatt tatatacagt tcatattgaa gtgatatagt aaggttaaag aaaaaatata
    45361 gaaggaaata aacatgtttg catcaaaaag cgaaagaaaa gtacattatt caattcgtaa
    45421 atttagtgtt ggagtagcta gtgtagttgt tgccagtctt gttatgggaa gtgtggttca
    45481 tgcgacagag aacgagggag ctacccaagt acccacttct tctaataggg caaatgaaag
    45541 tcaggcagaa caaggagaac aacctaaaaa actcgattca gaacgagata aggcaaggaa
    45601 agaggtcgag gaatatgtaa aaaaaatagt gggtgagagc tatgcaaaat caactaaaaa
    45661 gcgacataca attactgtag ctctagttaa cgagttgaac aacattaaga acgagtattt
    45721 gaataaaata gttgaatcaa cctcagaaag ccaactacag atactgatga tggagagtcg
    45781 atcaaaagta gatgaagctg tgtctaagtt tgaaaaggac tcatcttctt cgtcaagttc
    45841 agactcttcc actaaaccgg aagcttcaga tacagcgaag ccaaacaagc cgacagaacc
    45901 aggagaaaag gtagcagaag ctaagaagaa ggttgaagaa gctgagaaaa aagccaagga
    45961 tcaaaaagaa gaagatcgtc gtaactaccc aaccattact tacaaaacgc ttgaacttga
    46021 aattgctgag tccgatgtgg aagttaaaaa agcggagctt gaactagtaa aagtgaaagc
    46081 taacgaacct cgagacgagc aaaaaattaa gcaagcagaa gcggaagttg agagtaaaca
    46141 agctgaggct acaaggttaa aaaaaatcaa gacagatcgt gaagaagcag aagaagaagc
    46201 taaacgaaga gcagatgcta aagagcaagg taaaccaaag gggcgggcaa aacgaggagt
    46261 tcctggagag ctagcaacac ctgataaaaa agaaaatgat gcgaagtctt cagattctag
    46321 cgtaggtgaa gaaactcttc caagcccatc cctgaaacca gaaaaaaagg tagcagaagc
    46381 tgagaagaag gttgaagaag ctaagaaaaa agccgaggat caaaaagaag aagatcgccg
    46441 taactaccca accaatactt acaaaacgct tgaacttgaa attgctgagt ccgatgtgga
    46501 agttaaaaaa gcggagcttg aactagtaaa agaggaagct aaggaacctc gaaacgagga
    46561 aaaagttaag caagcaaaag cggaagttga gagtaaaaaa gctgaggcta caaggttaga
    46621 aaaaatcaag acagatcgta aaaaagcaga agaagaagct aaacgaaaag cagcagaaga
    46681 agataaagtt aaagaaaaac cagctgaaca accacaacca gcgccggctc caaaagcaga
    46741 aaaaccagct ccagctccaa aaccagagaa tccagctgaa caaccaaaag cagaaaaacc
    46801 agctgatcaa caagctgaag aagactatgc tcgtagatca gaagaagaat ataatcgctt
    46861 gactcaacag caaccgccaa aaactgaaaa accagcacaa ccatctactc caaaaacagg
    46921 ctggaaacaa gaaaacggta tgtggtactt ctacaatact gatggttcaa tggcgacagg
    46981 atggctccaa aacaatggct catggtacta cctcaacagc aatggcgcta tggcgacagg
    47041 atggctccaa aacaatggtt catggtacta tctaaacgct aatggttcaa tggcaacagg
    47101 atggctccaa aacaatgg
//
LOCUS       DAVKEV010000013        46089 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVKEV010000013 DAVKEV010000000
VERSION     DAVKEV010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46089
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.013"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..749
                     /locus_tag="VWZ68_000713"
                     /pseudo
     CDS             1..749
                     /locus_tag="VWZ68_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(865..1668)
                     /locus_tag="VWZ68_000714"
     CDS             complement(865..1668)
                     /locus_tag="VWZ68_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEU9371779.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(2048..3652)
                     /locus_tag="VWZ68_000715"
     CDS             complement(2048..3652)
                     /locus_tag="VWZ68_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU9371780.1"
                     /translation="MSEYWFSTNVDQIDEVDGKQCLIYSYYNVKASRNVEVLKGRSGT
                     KKGLDYWEPYAPQKQYEMERLPKNKYIGSSSTDRWDGIEKNVVFCDCKEYVSAFDLFF
                     YHYNFKKISTQRSKQDFIRLRSKPVADILKNNTSSYTRYKKEMVIDNVKVDDKVCEII
                     SEIMDESYTDIQILTHKLYSKGDDIKASKTIWMKKSGKEYSEAFAGTGEARIILLVND
                     IVNAQSNSLILIDEPEISLHPSAIYKFKEFLLQECLNKKHQIIITTHSTQLIKDFLRE
                     AVKLLVKNGEKVDVIENIDYQDAFFELGDVYHSRKMIYVEDRLAKYILEFVITHSGSE
                     NLKQNLVVRYIPGGANQIICNNILNSSYLDSDNHYFWFDGDQNTNVSESNNLMNYLEN
                     GVVISDKIPESDNKNLDDIIKLITGCPIKFNVSGNKGQKNNIELIAKQRSFIDYWAKY
                     VSYLPFPTPEFFLANLCNSVDREGYDFSKDGNGKEYFRKKTQVALGIENITSEDIFQE
                     QRRAVSKIQPESSMFQCIKEKLEALF"
     gene            complement(3703..3867)
                     /locus_tag="VWZ68_000716"
     CDS             complement(3703..3867)
                     /locus_tag="VWZ68_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEU9371781.1"
                     /translation="MGKIVAIDLFNGAGGTTSGLKKSGIDVQVAVEIDSVAVKTYKLN
                     NPEVSVIDME"
     gene            complement(3948..6599)
                     /locus_tag="VWZ68_000717"
     CDS             complement(3948..6599)
                     /locus_tag="VWZ68_000717"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEU9371782.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVIAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHSIMPFVTEEIFGQYAEGSIVTAAYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(6592..7170)
                     /locus_tag="VWZ68_000718"
     CDS             complement(6592..7170)
                     /locus_tag="VWZ68_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU9371783.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQSLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKYKPLKRHIEVSEREIIETAEILQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(7170..7730)
                     /locus_tag="VWZ68_000719"
     CDS             complement(7170..7730)
                     /locus_tag="VWZ68_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9371784.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHIFPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLDFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            complement(7717..8165)
                     /locus_tag="VWZ68_000720"
                     /pseudo
     CDS             complement(7717..8165)
                     /locus_tag="VWZ68_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
     gene            complement(8577..8972)
                     /locus_tag="VWZ68_000721"
     CDS             complement(8577..8972)
                     /locus_tag="VWZ68_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU9371785.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQPAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(9068..9322)
                     /locus_tag="VWZ68_000722"
     CDS             complement(9068..9322)
                     /locus_tag="VWZ68_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEU9371786.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(9332..10666)
                     /locus_tag="VWZ68_000723"
     CDS             complement(9332..10666)
                     /locus_tag="VWZ68_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEU9371787.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYEYMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKDDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(10666..10899)
                     /locus_tag="VWZ68_000724"
     CDS             complement(10666..10899)
                     /locus_tag="VWZ68_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEU9371788.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            10930..11007
                     /locus_tag="VWZ68_000725"
                     /pseudo
     CDS             10930..11007
                     /locus_tag="VWZ68_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(11348..11530)
                     /locus_tag="VWZ68_000726"
     CDS             complement(11348..11530)
                     /locus_tag="VWZ68_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371789.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(11532..12311)
                     /locus_tag="VWZ68_000727"
     CDS             complement(11532..12311)
                     /locus_tag="VWZ68_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371790.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            complement(12591..12941)
                     /gene="rbfA"
                     /locus_tag="VWZ68_000728"
     CDS             complement(12591..12941)
                     /gene="rbfA"
                     /locus_tag="VWZ68_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEU9371791.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(13192..15984)
                     /gene="infB"
                     /locus_tag="VWZ68_000729"
     CDS             complement(13192..15984)
                     /gene="infB"
                     /locus_tag="VWZ68_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEU9371792.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKTEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            complement(16001..16300)
                     /locus_tag="VWZ68_000730"
     CDS             complement(16001..16300)
                     /locus_tag="VWZ68_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEU9371793.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(16293..16586)
                     /locus_tag="VWZ68_000731"
     CDS             complement(16293..16586)
                     /locus_tag="VWZ68_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEU9371794.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(16608..17744)
                     /gene="nusA"
                     /locus_tag="VWZ68_000732"
     CDS             complement(16608..17744)
                     /gene="nusA"
                     /locus_tag="VWZ68_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEU9371795.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(17788..18267)
                     /gene="rimP"
                     /locus_tag="VWZ68_000733"
     CDS             complement(17788..18267)
                     /gene="rimP"
                     /locus_tag="VWZ68_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEU9371796.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMGKTRKKTVQIPYSLVSKARLAVKL"
     gene            complement(18393..19028)
                     /gene="trmB"
                     /locus_tag="VWZ68_000734"
     CDS             complement(18393..19028)
                     /gene="trmB"
                     /locus_tag="VWZ68_000734"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEU9371797.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQDPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(19025..19819)
                     /locus_tag="VWZ68_000735"
     CDS             complement(19025..19819)
                     /locus_tag="VWZ68_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEU9371798.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(19980..20591)
                     /locus_tag="VWZ68_000736"
     CDS             complement(19980..20591)
                     /locus_tag="VWZ68_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9371799.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            complement(20742..20975)
                     /locus_tag="VWZ68_000737"
     CDS             complement(20742..20975)
                     /locus_tag="VWZ68_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371800.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            complement(21017..21706)
                     /locus_tag="VWZ68_000738"
     CDS             complement(21017..21706)
                     /locus_tag="VWZ68_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9371801.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            complement(21758..22141)
                     /locus_tag="VWZ68_000739"
     CDS             complement(21758..22141)
                     /locus_tag="VWZ68_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU9371802.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            complement(22770..23141)
                     /locus_tag="VWZ68_000740"
     CDS             complement(22770..23141)
                     /locus_tag="VWZ68_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371803.1"
                     /translation="MIKKNHILCEIVPGAVAFACFYLSISISSVFQFLLVVINLASIL
                     VTVYLTREMRIKEFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQLIAYI
                     GAILCLIIMLLLIWGLKYYKK"
     gene            complement(23610..23729)
                     /locus_tag="VWZ68_000741"
     CDS             complement(23610..23729)
                     /locus_tag="VWZ68_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEU9371804.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            complement(23833..23982)
                     /gene="blpO"
                     /locus_tag="VWZ68_000742"
     CDS             complement(23833..23982)
                     /gene="blpO"
                     /locus_tag="VWZ68_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEU9371805.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(24226..24429)
                     /gene="blpN"
                     /locus_tag="VWZ68_000743"
     CDS             complement(24226..24429)
                     /gene="blpN"
                     /locus_tag="VWZ68_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEU9371806.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGKILGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(24445..24699)
                     /gene="blpM"
                     /locus_tag="VWZ68_000744"
     CDS             complement(24445..24699)
                     /gene="blpM"
                     /locus_tag="VWZ68_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEU9371807.1"
                     /translation="MNTKMMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            24979..27104
                     /gene="blpA"
                     /locus_tag="VWZ68_000745"
                     /pseudo
     CDS             24979..27104
                     /gene="blpA"
                     /locus_tag="VWZ68_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
     gene            27115..28476
                     /locus_tag="VWZ68_000746"
     CDS             27115..28476
                     /locus_tag="VWZ68_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEU9371808.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVISSIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGIFKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIVNKRARLPTGNPHQSILNRY
                     LIASQEQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            28533..28688
                     /gene="blpC"
                     /locus_tag="VWZ68_000747"
     CDS             28533..28688
                     /gene="blpC"
                     /locus_tag="VWZ68_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEU9371809.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FHQPIQL"
     gene            complement(28732..30072)
                     /locus_tag="VWZ68_000748"
     CDS             complement(28732..30072)
                     /locus_tag="VWZ68_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9371810.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLLKFLL
                     GIIFTTFQFLAVSKYLSYFIEPLFGIGLSFLLLRGLPKKILIFYGLFPMILVELFYRG
                     VSYFVLPFLGQGIVDGDGNPIFLLIMIFVCFIVLVFLKWLDYDFTRLRREFLDTGFQK
                     SLTKINWAMGAYYLVMQSLSYLEYEQGIQSTTVRHLILVFYLLFFMGGIKKLDTYLKE
                     KLQEELNQEQTLRYRDMERYSRHIEELYKEIRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLRDSSQKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTVVSILCDNAIEASVEACQPHVSIAFFKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(30086..30823)
                     /locus_tag="VWZ68_000749"
     CDS             complement(30086..30823)
                     /locus_tag="VWZ68_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9371811.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(30828..31166)
                     /locus_tag="VWZ68_000750"
     CDS             complement(30828..31166)
                     /locus_tag="VWZ68_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9371812.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            31442..31771
                     /locus_tag="VWZ68_000751"
     CDS             31442..31771
                     /locus_tag="VWZ68_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU9371813.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(31939..32988)
                     /locus_tag="VWZ68_000752"
     CDS             complement(31939..32988)
                     /locus_tag="VWZ68_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9371814.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(32985..33716)
                     /locus_tag="VWZ68_000753"
     CDS             complement(32985..33716)
                     /locus_tag="VWZ68_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9371815.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            33784..34194
                     /locus_tag="VWZ68_000754"
     CDS             33784..34194
                     /locus_tag="VWZ68_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU9371816.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            34204..34491
                     /locus_tag="VWZ68_000755"
     CDS             34204..34491
                     /locus_tag="VWZ68_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371817.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            34653..34892
                     /locus_tag="VWZ68_000756"
     CDS             34653..34892
                     /locus_tag="VWZ68_000756"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371818.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(35214..36350)
                     /gene="dnaJ"
                     /locus_tag="VWZ68_000757"
     CDS             complement(35214..36350)
                     /gene="dnaJ"
                     /locus_tag="VWZ68_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEU9371819.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFATAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(36555..36809)
                     /locus_tag="VWZ68_000758"
     CDS             complement(36555..36809)
                     /locus_tag="VWZ68_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371820.1"
                     /translation="MLVTVERNGNVIYKEFTEVAVGKSKYDHTSVFKDVMIYFSDHIC
                     QELHLYKTQDPHYNKFEFDLAKRSLKITTRDNTTIFISNE"
     gene            complement(36922..38745)
                     /gene="dnaK"
                     /locus_tag="VWZ68_000759"
     CDS             complement(36922..38745)
                     /gene="dnaK"
                     /locus_tag="VWZ68_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEU9371821.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(39225..39749)
                     /gene="grpE"
                     /locus_tag="VWZ68_000760"
     CDS             complement(39225..39749)
                     /gene="grpE"
                     /locus_tag="VWZ68_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEU9371822.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LAMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(39776..40810)
                     /gene="hrcA"
                     /locus_tag="VWZ68_000761"
     CDS             complement(39776..40810)
                     /gene="hrcA"
                     /locus_tag="VWZ68_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEU9371823.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(40974..41411)
                     /locus_tag="VWZ68_000762"
     CDS             complement(40974..41411)
                     /locus_tag="VWZ68_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEU9371824.1"
                     /translation="MHLKGWRYRTSRFGLFYFDQCQPDDVIYRIYDSRFLKKYKHELQ
                     DFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMSKGLKWEVMRSRLRSCTTTFLGGLV
                     VCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFRLKRKYRVDE"
     gene            42091..44424
                     /locus_tag="VWZ68_000763"
     CDS             42091..44424
                     /locus_tag="VWZ68_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU9371825.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            44437..45900
                     /locus_tag="VWZ68_000764"
     CDS             44437..45900
                     /locus_tag="VWZ68_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU9371826.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFKDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            45900..>46089
                     /locus_tag="VWZ68_000765"
     CDS             45900..>46089
                     /locus_tag="VWZ68_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HEU9371827.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT        14151 a         9766 c         8328 g        13844 t
ORIGIN      
        1 aaaacagata aggaccaaga gcttaaagct gaaattcaat ccatctttat cgaacacaag
       61 ggaaattatg gttatcgtcg gatttattta gaactaagaa atcgtggtta tctggtaaat
      121 cataaaagag ttcaacactt gatgaagtac tcaatttaca agctaaaatg cgacagaaac
      181 gaaaatattc ttctcataaa ggagacgttg gcaagaaggc agagaatctc attcaaggcc
      241 aatttgaagg ctctaaaaca atggaacagt gctacacaga tgtgacagaa tttgccattc
      301 cagcaagtac tcaaaagctt tacttatcac cagttttaga tggctttaat agcgaaatta
      361 tcgcctataa tctttcaact tcacccaact tagaacaagt acaaacaatg ttggaacagg
      421 cattcacaga gaagcactat gagaatacga ttctccatag tgaccaaggc tggcaatacc
      481 gacacgattc ttatcatcgg ttcctagaga gtaagggagt tcaagcatcc atgtcacgca
      541 agggaaacag ccaagacaac ggtatgatgg aatctttctt tgggattctg aaatcggaaa
      601 tgttttacgg ttatgagaag tcgtttcagt cgcttaagca attggaacaa gctattgtag
      661 actatattga ttactacaac aataaacgaa ttaaggtaaa actaaaagga cttagtcctg
      721 tgcaatacag aactaaatcc ttcggataaa ttaattgtct aactgtttgg ggtcagtaca
      781 cctaaaactt tgatgatata cgttttcttg tgagaatatt tacttcattt ttgcctaaaa
      841 ttcaatgttt actcagtatt tggattatga aaaatcaagg tctaaatcta gatacatttt
      901 ttctgaagac aaatcatttt gaccaccgag caagagattt tcaaaaaaag ctgttaaaaa
      961 ctcaggacgt cgctgtaaaa tctttgcatt atctaatacc aaggcatcac gaaaatattt
     1021 ggaatgttgc tgaaatggtg tattatcaat atcaaaacca aactcacgaa gatactgaat
     1081 caaaaagacc gttactgtcc gagtgtttcc ttcgcgaaat ggatgaatct gccagattcc
     1141 tgaaataaaa tgctggattt gtttaaccac atccgcctga gttagtgtcg catatgcaac
     1201 ttgtttttcc tgattaaaat cataatctaa ggtcatttga atcatggagt aatcagagta
     1261 cacaacactt tcaccattca aaacaggttc attctttgtg atattggtct gacgaaattg
     1321 ccccaccgga atagagggtt caaatatatc ttgaaacaac tccttatgaa tagcaagtaa
     1381 ggtcgcagga ctaaagctaa agcctcttcg agacaatagt tctacaatac gtagagaaac
     1441 caagtctgcc tcttccgtac ttgcatcaat agtatggtga taagccgttg catcctcata
     1501 aacctgctca taagtcagtt ctccccggga ctgtttctca gccaaagatt ccatatacgc
     1561 tgatggcact agattgtcaa ctttctgcag accaaaacct atccgccata aatcacgctt
     1621 cgcttcataa gacaagtttg gattgtcaat gttgtaagtt ggttgcatag aaatatcctt
     1681 tcaattgttt ttctgtgtca tcggtaaatg gtgaaatggg tatggaattg gcgaaaatta
     1741 taaaaatcct tcacaataag ttctatgaaa tatatatact tcatcttaat agtgagcaag
     1801 ctaaacttag catttcatgc cctcatatgg gatgttcttt gactaaataa tatgattatc
     1861 gagatatatc tggataaatg aactaataag tctgacgcgc atacttatca aactcattgg
     1921 catacacctc tatgaactcg ttggtctgtt caaatcccaa cacattacct gagaagaaag
     1981 ttgcaatgtt gtttttggtg cgggtttgaa tttaaaaaat ttgttatgta gtacctaatc
     2041 taaggaatta gaacaatgcc tctaattttt ctttaataca ctgaaacatt gatgattctg
     2101 gctgtatttt tgaaacagct cttctttgct cctggaaaat atcttcagaa gttatattct
     2161 ctattcctaa cgctacttga gttttttttc taaaatattc ttttccgttg ccatctttag
     2221 aaaaatcata accttcccta tctacgctgt tacacaaatt agctaaaaaa aactctgggg
     2281 ttgggaaagg aagataagaa acgtatttag cccaataatc tataaagctt ctttgtttcg
     2341 caattaattc aatattattt ttttgccctt tattacctga aacattaaat ttaattggac
     2401 atcccgttat caattttata atatcatcaa gatttttatt atctgattca ggaattttat
     2461 ctgatataac aacaccattt tcaagatagt tcattaaatt atttgattca ctaacattag
     2521 tgttttgatc tccatcaaac caaaaataat ggttatcgga atctaaatac gatgagttta
     2581 aaatattatt acaaattatt tgatttgctc caccaggaat atatctcact actaaattct
     2641 gtttaagatt ctcactacct gaatgagtga taacaaactc tagaatatat ttagctagtc
     2701 tatcttcaac ataaatcatc ttcctagaat gatacacatc acctaattca aaaaatgcat
     2761 cctgataatc aatattttca ataacatcta ccttttctcc gtttttcact aaaagtttca
     2821 cggcttctct aagaaaatct tttataagtt gtgtagaatg tgtagtgata ataatttgat
     2881 gttttttatt taaacactct tgaagtaaaa actctttaaa tttatagatt gcactcggat
     2941 gaagtgagat ttcaggttca tctattaata ttaatgaatt tgattgcgca tttactatat
     3001 catttactaa caaaataatt ctagcctcac ctgttcctgc aaaagcctcg gaatattctt
     3061 ttccagattt tttcatccaa atagttttgg aagcttttat atcatcacct tttgaataca
     3121 acttatgtgt taaaatttga atgtctgtat aagattcatc cattatttca ctaataattt
     3181 cacaaacttt atcatcaact ttaacattat ctataaccat ttccttttta taacgcgtat
     3241 aactacttgt attattcttt aaaatatcag caactggttt agatcgtaat cttataaaat
     3301 cttgtttact acgttgagta gaaatttttt taaaattata gtgatagaaa aataaatcaa
     3361 aagcagaaac atattcttta caatcacaaa agacaacatt tttttcaatg ccatcccatc
     3421 tgtctgtcga agaacttcca atatatttat ttttgggtaa tctttccatc tcatattgtt
     3481 tttgaggagc atatggttcc caataatcta atcctttttt tgttccagaa cggcctttaa
     3541 gaacttctac atttctagaa gctttaacgt tataatatga atagattaaa cattgtttcc
     3601 catccacttc atctatttga tcaacatttg tactaaacca atattcagac acacttttat
     3661 tggctggaga accatataaa gcttgtaaaa ttgaagtttt atttactcca tatctattac
     3721 agacacctca ggattattta acttataagt tttaacagct acggaatcaa tttcaacagc
     3781 aacttgaaca tctatgcctg attttttaag gccacttgta gtgccacctg caccgttaaa
     3841 taaatcaata gcaacaattt tccccatagt attctcctaa agtttctcct ttttattata
     3901 acattatcaa atgtaaaacc caacccgata gggttaggtt tttaacatca tttcaccaac
     3961 ttcttcatct catcaatacg tgctacggtc gcatcatact tggcttggta gtcggcttgt
     4021 ttgtcttttt ctttttggac aacttctggt ttagcgttgg cgacgaagcg ttcgttgctg
     4081 agttttttgc caaccatgtc gagttctttc tgccatttgg caagttcttt ttccagacgt
     4141 gccaattctt cttcgacatt caagaggtct accagtggca agaagatttc ggctcctgta
     4201 ataacgcttg acatagccag ttcaggtgca gggatggttg atgcgatttc caagtgttct
     4261 ggatttgtaa agcgtttgat atagttgaca ttgctgttaa agaaggcttc caagtcgcta
     4321 tcgcttgtct taacaaggat ggtgataggt ttgcttggtg ctacatttac ttccgcacgc
     4381 gcattacgaa cggcacggat caagtctttg agactttcca caccagtgtg ggcagcaagg
     4441 tcctcaaagg ctgggttgac agttgggtat gctgctgtca cgatagagcc ttcagcgtac
     4501 tgaccaaaga tttcttctgt cacgaacggc attattgagt gaaggagacg aaggatttta
     4561 tccagcgtat agaggagaac agatcgagta attaccttat cgtcttcatt gtcgctgtaa
     4621 agaacttcct tggtcaactc aacataccag ttggcaaatt cttcccaaat gaagttgtaa
     4681 aggatatgac cagccacacc aaactcgaac ttatcaaagt tttcagtaac ttttgcaatg
     4741 gtttcgttga gattgtggag aatccagcgg tccgtcacat taccagcctc acctgttgca
     4801 acttttgtga cattgtcatg cgccacatcc agcgtcaaac ctccattgtt catgaggata
     4861 tagcgagaaa tgttccaaat cttgttaata aagttccatg aagcatccat tttctcataa
     4921 gagaaacgca cgtcttgtcc tggcgcagaa ccgtttgaaa ggaaccatcg aagggcatcg
     4981 gcaccgtatt tctcgataac atccattggg tcaatcccgt taccgagaga cttagacatc
     5041 ttgcgtcctt gctcgtcacg aatgagaccg tggataagga cgttttggaa tggttgacgg
     5101 cctgtgaatt ccaatgactg gaagatcata cgagacaccc agaagaagat gatgtcgtaa
     5161 cctgttacca aggttgaagt tgggaaataa cgtttaaagt cttctgagtc gacttcaggc
     5221 cagcccatgg ttgaaaatgg ccagagggca gaactgaacc aagtatccaa gacgtcttcg
     5281 tcctgagtcc atccgtcacc ttctggagct tcttcgccga catacatttc accatcagca
     5341 ttgtaccagg cagggatttg gtgaccccac caaagctgac gagagataac ccagtcgtgg
     5401 acattttcca tccattgaag gaaggtatcg ttgaaacgag gtgggtagaa ttcgaccttg
     5461 tcctctgtgt cttggttggc aatggcgttc ttagccaatt ggtccatctt gacgaaccat
     5521 tgagtagaca agcgtggctc aactacgaca cctgtacgtt ctgagtgacc aacactgtgg
     5581 acacgttttt cgattttgac aagggcaccg atttcttcca acttagcaat gactgcctta
     5641 cgagcttcaa aacgatccat gcctgaaaat tcaaaggcaa gctcattcat agttccgtcg
     5701 tcgttcatga cgttgacttg tggcaagtta tgacgttggc caaccaagaa gtcatttgga
     5761 tcgtgggcag gtgtgatttt cacgacacca gtaccaaact caggatctgc gtgctcatct
     5821 ccaacgattg ggatgagttt attagcgatt ggaaggatga cgtttttacc aatcaagtcc
     5881 ttgtagcgcg ggtcttctgg attaaccgca accgcaacgt ccccaaacat agtctcagga
     5941 cgagttgtag caacttcaag ggcgcgtgaa ccatcttcca gcatgtaatt catgtggtag
     6001 aaggcacctt ccacatcctt gtgaatcacc tcaatatcag aaagggctgt gcgagctgct
     6061 gggtcccagt tgatgataaa ctcaccacgg tagatccagc ctttcttgta aaggtccaca
     6121 aagaccttac gaacagcttt tgacaaacct tcgtcaagag tgaaacgctc acgagaatag
     6181 tctacagaga gccccatctt gccccattgt tccttgatgg tagtggcata ttcgtctttc
     6241 cattcccaga ctttcgtcaa gaaagactca cgaccaaggt catagcggga aatgccctca
     6301 ccacgcaagc gctcctcaac cttagcctga gtcgcaatac cagcgtggtc cattcctgga
     6361 agccaaagcg tatcaaaacc ttgcatgcgt ttttgacgga tgataatatc ttgcaaagtt
     6421 gtatcccaag cgtgaccaag gtgaagttta cctgtaacgt ttggtggtgg aataacgatt
     6481 gaataaggct tagccttttg atcgcctgaa ggcttgaaaa catcagcatc aagccatttt
     6541 tggtaacgac cagcctcaac ctcggctgga ttgtatttag atgaaagttc tttagacatg
     6601 tgtgtgtcct ttctctattt tgtttatttt attttgaatt tgcttagcag cttcttctgc
     6661 agacaaattc gtattattta ttttaaagta gtggtgcaac tcattcggtt gatattggga
     6721 atttaattga agtatttcag cggtctctat aatttctctt tcagatacct caatatgtcg
     6781 ttttaagggt ttgtacttta atcgattctc cgttcgattt cgacgtatgc actcttcaag
     6841 acttgtttcc aactcaacaa aaagaatctc ttgatgataa tcatccaaca aactctgaat
     6901 ttgctttaaa tatatcagat gatactgatt tgaaaaatca attacatctg ttaaaattac
     6961 tgatcgctga tttcttgcac tcgctccaag gaatgaaaaa gtgattccac gaacaaattc
     7021 ccacatttcc tctgtatagt cctgatagat ttctagtgca aaatcgatgg cttgatggtt
     7081 ataaaatagg gtagcatccg tcagtcgaga taattcttga ccaatggtca tttttcctga
     7141 tgctggagca ccaatgatga aaagatgcat caaatcacct cccattcact cttcagcaag
     7201 gcatatctta aatcatcaca gcagttgcct tgagcatctt tgcggtctct tatgcgagct
     7261 tcgagggtaa agtcaagctt ttccgcgact cgtttacttt gaaggttata tccaaagcaa
     7321 gttagttcaa tcttgtgaag acccaaatct ttaaaggcta agtcaatcaa ggcacgcgca
     7381 gcttctggca cataacctcg cccccaatag tctgggtgta aggtatagcc gatttccagc
     7441 acatcatctt catggcgatg gttgaaatcg acagagccaa cgatcttatc cgttcctttg
     7501 acgacaatcc cgtagcctgc tgggagattt tccttttgat tacgctccgg aaaaatgtgc
     7561 tccagataat aaatctcatc ttccaaggtc ttgactggag gaaaacctgc tggataggcg
     7621 acctctggca aactagcata gtcaaagata tcctcagcat ccgccacagt acggactcgt
     7681 aaaacgagac gttctgtttc gattttatct ggcagctcag ttcttgccat ccttcttcct
     7741 cgcttttttg atgaaactgc ccttcatatc tacacgcttg tccagatagc aataaatgcg
     7801 ctgatatcca tctcccatga aataggttgg gcaaacagtt gatttttaaa atgtcccttt
     7861 tcatccagga gttctggggc aacaagtcgc tcaagaatct tggcaaagat gtggcaaata
     7921 ccgtattcct caacaatcct atctacccga taatctaaaa caagtggaca ggcgtctaaa
     7981 ataggagtct gagttcgttc agaaatttca taatgcactc ccaaacgttc caatttctcc
     8041 tgatgactga taaaaccagc ctgctccatc gcaagcatag aagtttcatc agaaatattc
     8101 acagtaaatt tttgatattg tttgatctgc tctgcggcat tctctctcgc aacgactcca
     8161 atcacaaccc aatctcctag actataagag gaactacagg tcatgatgtt atagctaaaa
     8221 ttctgatctt gatatcctaa aataaaaaca ggaaaaccat aatatagttt attagtttta
     8281 aatgattgtt ttataacaac ctcctttgac taagacacaa aagaaaagcc ctgccatcta
     8341 catgacaggg acgaatgtgt ttatccgcgg taccacccaa tttcgggcca agcccgcatc
     8401 tttagtcttt aaaataaaaa gacagaaata tttcattttt tcagtcatta gcaaccagtt
     8461 ttgacacatt tgtggacttc tcagcgccgc cactttctgt aaaatgtggg attcaaaaca
     8521 cctctaatgg ctctattgta gcaagttttt ctcggaaatg caaggctcaa gaaaaattac
     8581 ttgaacttga tgccattttc tttcaatttc ttgatggtag ctgggccgat tcctttcaag
     8641 gcaaggagtt ctttttcagt ccagtttttg aaatctgaag cagacttgat tccttcatca
     8701 tagaaagtct tggcacgatc aagtggaagt ccccccaagt ttgctgcaaa atcttctaca
     8761 gaattagcta ctttttgagc ttgctctttg gtagcttcta ctgcttgttc aactttttta
     8821 gaaacagcct taccagctgc gcttgctggc tgttctgcac gcttcacgac tttttttgtc
     8881 tcatctacaa ccttagtcac agtacttgaa aaggcacctg cgcgacggag gccatttcgt
     8941 aattgttttt tacgattgag tttctttgac atgataaaat cctttcaata aaaaatccct
     9001 gctctgacaa ggatttaaca taaacattct atcaagattt tagtgaaaaa tcaagaatct
     9061 ttctcgttta ataatttcgc tcaccaaaca agccttctgg caaatcatgg aatcccttgc
     9121 ctgctttgaa gttttcaaac ttaccaagca agaactgata agcatccaag cgactctcgt
     9181 agcgaatcat ggcatctttg gcacgctcgt cctggtcttc ttcgtaaact ttttgacttt
     9241 ccttgtgcgc catgtcgtta atcatgattt gggtattgac ccaagcttca aattccttca
     9301 taaattcttg ttcgtaactc attttttctc cttattctaa tccacgaaaa tagtccgtat
     9361 caatctcacg gtagggctgg atatcctgaa catactccaa cactccttgg aattctccgt
     9421 cttcatcgtg tactgcagca taggtgatgt ggacaaactt acctcgcgac tcagacttga
     9481 accacatttc atacttgtct ttgcttccct cacgaagccc cttcatgata gttttgacct
     9541 tgtccaagta cttaggcgga tggcagagtt cgacattgcg cccgacttga gacggcgtcc
     9601 gtttgaaaat catctcatca gctggcgtat tgtcattgta atactggaaa atatcatctt
     9661 tattgacaaa ggtaatctcc atagggaggt gattgaggat gagattggcc tgctcgactg
     9721 aaagatagcc attaccaaaa gcctgttgac tatggcggtc cagcacagct tccttttcct
     9781 taggggtaaa ggtaatggta aaatggcctt ctggcgtatc tatgacttgt tgaacttgac
     9841 cttctgccgt atctagctgt acaggctcct ctgcaatctt ttcctcaata aagctctgtc
     9901 gttctggcac ccatttctct gacggacgga tgatggcata gccataggca tcgctctcct
     9961 ccgcaatctg aagccagtca tcctgagtaa aagactcaag gagaatcatg aggaggatgg
    10021 actcttcctt gaaaatcata ctttcaaact ctgtcgcaaa agcttcaaaa gcttccttta
    10081 cactgctaat tgacacttct ggtagtgact tggctgtcgt tagagctgtt tgaaagagtt
    10141 ccctaatctg atcatccact ccccacataa ctttgggagg tgaatcgtgt ccatagcgct
    10201 ccatgatagg aaagaagagt tcttccttac gttggtaatg gatgtcaaat tgacccacaa
    10261 gtcccatctg acgcaccaaa cccttacgca tctccgccag catttcctcg tcttccatat
    10321 actcataggt atctaacaat ctacgaatgc gaatcaaggc cgcacggaga gccagatttt
    10381 cttctttgaa gacacgaact gggtgacctg gatgctcagt atctgaaact tcgacacctt
    10441 tgatagcatt tttaaaaaga ttggcatgga catcacagag ttccataaca tcttcaaagg
    10501 tgacacctga gtctgagttc atcagctcgt gctccataag ggaaatctcg atggctgaga
    10561 cacccgcaaa ggtcgcatca aagcgctctt gaaccgactc aggagaggcg ccattgtgca
    10621 attctaacaa aatatcccgt aggacatgaa tccgttcatc tgccattagt ctaatccaat
    10681 cacttcgtag ccattcgctt ccagtgtgcg tacaatcttg tccataggag ttcctgctag
    10741 cttagaaccc tgtttgagcg ataccttgcg accaactgta ttgcgcatta agggattggc
    10801 aaggggttta aaacccaact ccactagaat ttccaagact tctggatgct tgtccaccac
    10861 ttctgcaaca ggaattgaca catcgatgat attgtccatg acgacctcca ttgtatgttc
    10921 taatactcaa tgaaaatcaa agagcaaact aggaagctag ctgcagactg ctcaaaacag
    10981 tgctttgagg ttgtggatag aactgacgaa gtcagctcaa aacaccgttt tgaggttgta
    11041 gatagaactg acgaagtcag taaccatacc tacagcaagg tgaagctgac gtggtttgaa
    11101 gagattttcg aagagtataa aatgatttta ctgcttatat tataccatat ggagagagat
    11161 taaaaaacta gcagtggggt tcctgctagt tttctgcgac ttggattacc atctagataa
    11221 gtttaaagaa ccaatccaat atcttgtaaa acagcaattg aactgcaaaa gaaatgatca
    11281 tccaaaagaa tttcacaatc ccaataatcg gtttgataaa aagaatagca agaagaccaa
    11341 aaaaatttca ttctctctcc tctggcttaa tgagccaccg agccgtatcc attagcttat
    11401 ctgcaataaa aagtttgccc agaccaacaa cgacatggtc agctttcttt atcgttttca
    11461 tcacttttac accttgcacg gtcaaaaagt aattaccata aattttagct agagttttta
    11521 tgagtcccat attactctcc ttcgatgatt tcagcctctt ttcggattgt ttcaacatct
    11581 tcttgatatt gaacttcact atagttaact agcttggaca attctttctg caagctttca
    11641 cccatcggtt tcatagttgc aaaggttaaa ccacctgaaa tgataccacc caagatagga
    11701 ataaatttcc ccattccttt ggccagccct cccttggtaa gattcacacc aaatattctt
    11761 aagacttttt tcaaaatagg ataccaaagc gtcttagtta aagctttatt aggtactgtt
    11821 ttcattacct gtttggcaat tgttatacca ccagcacgta gcaaagcagc agttccattc
    11881 acccccaaca tgacgcctag ataaagcaag agggtatttt gagcatcttc actcaactca
    11941 tcgcgtgaag cccaaagatc ctcataacca taaatataac ctaattcttg ggccaatttc
    12001 agagagaaag cataaaattg agccacatca gctggaatgg taattgccat agcaagccct
    12061 ccaggtaatc ctgccaaaac agaagtccca ctcgctaata aaacattatc cctaatacag
    12121 gcattagcca ctcgatctaa gatttcttga gataagagag acgttggacc ttgttccaat
    12181 aaggtaggaa tgtcctgtgg acccaattct ttggaaaact tatccactaa aaatttcgaa
    12241 cgatcaacct taacaactgg tagttttacc acttgttgta atacttgcat agctaagtct
    12301 tgttcagcca tatacaaact ccttatttct tttttacacc ttatcatatt atatttccta
    12361 caaaaaaagc attttctaat tagataacat taaaaaatac agaacccctt tttttatagt
    12421 aaaatgaaac acgaacagga caaatcgatc aggacagtca aatcgatttc taacaatgtt
    12481 ttagaagtag aggcgtacta ttctagtttc aatatatttt aaaagaatat ttttccattt
    12541 caaattcaac ctattttcct ccaccaaaaa agaggggcaa cccctcttct ttagttctta
    12601 tccagattgc gtagcatctc gtcaatcttg tttccatact cgatggactc gtctttgacg
    12661 aaggtcaaat ctgggatttt gtacaatttc aaattgcgac caagttcacg tttgatggta
    12721 ccagttgctt tttcaagccc gatttgggct ttttggttat ccgaagcaag gttactcaaa
    12781 atggtgtaat aaaccttggc aacagacaag tcacccagca tctgaacatc tgtgatggtc
    12841 acaccttgga cacgtggatc acggactttc ttttgcaaaa tctcattgac ttcacgcttg
    12901 atttccatgc ccacacgatc tgtacggaaa tgatttgcca tgatattcct ttctctactt
    12961 tgaaccaaaa gctaggccag cagacctagc tattttaaac ttcttgattt tcagtttaaa
    13021 ttgaaacgaa gttcaatttg aagtcatctg cttctttcgc cgtggtgaaa gtgatggaac
    13081 tgatttatca gtcccatcac aggggatttt tgagacccta ggctcaaaaa taagcaatga
    13141 aaccatcggt ttgcttgcgt ccctcaccac ctaagaaagg agcaaaaaat cttatctctt
    13201 gatttcttcc atgacatacg cctcaatcac atcatccatc ttaatatcat tgtagccgtc
    13261 gatcatcaat ccaccttcac ggccgtttgt aacttcctta acgtcgtctt tatagtgttt
    13321 caagcttgcg agttcaccat catagataac gacaccatca cggataacac ggactttaga
    13381 gtcacgggca accttaccgt tgataaccat aaatccaccg atagttccca ctttagacac
    13441 cttgaaggtt tcacggataa ctgcttcacc aataactttt tcttcaaatt ctggatcaag
    13501 catccctttc atagcttctt ccatctcttc gataaccttg tagataatgc tgtgaagacg
    13561 gatttccaca tcgtcagctt ctgcttgttg acgagcttgt ggtgtagggc gtacgttgaa
    13621 accaacgata aaggcatttg aagcttcggc aagggtcacg tctgattcgt tgatagcacc
    13681 gaccgctgag tggacgatag tcactttgac accttccacg tcaatctttt gaagtgaggc
    13741 agaaagggct tcaacagaac cttgtacatc agccttgatg ataacattaa cagatttgag
    13801 ttccccagct ttaagggtat caaagaggtt ttcaaggcta acacgttggg tagcttgacg
    13861 ttgtttcatg agggcacgtt tggcacgctc ttcacctgct gcacgcgcag atttttcatc
    13921 ctcgtaaacg gcaaagtggt cacccgccat cggtgcttcg ttcaaacctg tgatagagac
    13981 tggtgttgat ggtccagcaa ctttaacacg acgaccaagg tcgttggtca tagcacggac
    14041 acgaccgaag gtatttccga caacgattgg gtcttgaaca ttcaaggtac cttgttgtac
    14101 aagaagggtt gcgaccgcac cttttccttt atccaagcgc gcttcgataa ccgtaccgat
    14161 tgcacgcact gttgggtctg ccttgagttc ttggatttca gctacaagaa ggactgtttc
    14221 caacaattct tcgatatttt ggttgaattt agctgagatt tcaacaaatt cagaatctcc
    14281 accccaagca gttgacataa ctccatgctc tgccaattca ccgataacgc gttctgggtt
    14341 agcacctggt ttatcaatct tgttaatggc tacgatgatt ggaacgttgg ccgcttttga
    14401 gtggttaatg gcttcgatag tctgaggcat aaccccgtca tctgccgcta cgaccaagat
    14461 cgtaatatcg gtaacagaag caccacgcgc acgcattgat gtaaaggccg cgtgtcctgg
    14521 tgtatcaagg aaggtaatct tcttaccatt ttccacgatt tggtaggcac cgatatgctg
    14581 agtaatacca cctgcttcac ctgtcgcaac acgtgagtta cgaagagtat ccaaaagggt
    14641 tgttttaccg tggtcaacgt gtcccatgat agtaacaact ggtggacgct caaccaattc
    14701 atcttcattg agataaccat cttcgacaaa gaaacgttcg atgtcagcat tatccacttc
    14761 aaccttttgt ttggcttcga taccgtaatc caccatgagg agttcaattg tttccccatc
    14821 caaggattgg ttttgtgtgg ccatgacacc catcatgaaa agtttcttaa caatttcagc
    14881 tggttcacgt ttgatacgtt ttgcgatttc cgcaacggtc ataccatctg tatattcaaa
    14941 ttctgttggc aattcatgga atttacgctc cgtaacaggt tttggagtct gattacggtt
    15001 gttcttgtta ttgccttttt tgttcttttt gttgttattc cagttactat tcttttgatt
    15061 tctcacttga ttttgactac ttcgattctt ttgttgtttt ctaggaccat cttcttcatg
    15121 atcataatcg tcacgatttt tgtctggtcg agcttgtttt ttacgacgtg tatccactgc
    15181 aggttctttt ttctcaggga cgacttcaac cactgcttga acttgctgtg cttgttcagc
    15241 taacttagcc gcttcttcaa agatttcctc tggttccttg cgtttgttag cttgagccaa
    15301 ggcttcttta gcagcctgat actgcttgaa gcgttcctca cttgaacgag cgtactctgc
    15361 attttgctct gcttttaggg ctgctgcacg ggctttaaag tcaatacgtg gagccgcttg
    15421 atttgaacgt ttgtcctctt gctgacggcg ctcatttcta cgtttttgct gaccttgctg
    15481 cttcttagct tggtcattaa agcgacgatt gtcgcggttg ctttgacctt gttttccacc
    15541 attacggcca tcgtttttct gacggtttcc gttttgttgt tggtcacggt tattgccctt
    15601 attttgcttg cgtcgttctg cctgctcttt agcacgggct tcacgctcag ccttgaaatt
    15661 acggctttgc ggtttcgctg ctactttttc tgttttcgga gcaactggct cagccggttt
    15721 tgcctcttcc ttagctacag ctggtttagc tggctcagat ttttcggttt tcttttctgc
    15781 acttactttt ggtgctgcag gttttgcttc tactttcgga gcagctgcag gcttaaagct
    15841 ggcagcaatt tttgcagcga cagcttcttc cacacttgat gagtggcttt tcacatccaa
    15901 gcccaactct tttgcacgcg ctacaacttc tttactttct tttccaagtt cttttgcgat
    15961 ttcgtacaat cttttcttag acaaatcatg tcctcctctt ctattccata agagacctca
    16021 ttttctttgt aaatccagca tctgttacag ccaaaacctt tctcgatttc ccgactgcta
    16081 tgcttaattc cagtgttgaa aacacggtta caatttctac ttgataataa tgacttttat
    16141 cttgaatctt cttggtcaga ttgggtccag catcatgagc tagaaagacc aacttggcct
    16201 tgccgtcttg aatggccttg accaccaatt cttcacccga tatgatgcgc cctgctcgct
    16261 gagcaagccc caagagatta cttatctttt gcttattcaa gtcccaactc tcttcttttc
    16321 actttgtgat ccacataagc gatcaactcg tcataaaagc tttcttccac ttccatgcta
    16381 aagctgcggt taaagacctt cttctttttc gcctctaggg cttctgcatt gtctagtttg
    16441 atataagcgc cgcggccatt ggccttgccc gtaggatcaa taaagacttg tccttccttg
    16501 ttcttgacaa tgcggagcaa atcacgctta tcaatcactt cgttagacac aacagacttg
    16561 cgcaaaggga tttttcttgt tttcatcttt ccctcctcta gcagctttta ttcttctaca
    16621 gtatcgtttt ctacttccaa ctctactgaa gcagcgtctt ccatggcttc aaattcgcta
    16681 gcagacttga tatcgatacg gtaaccagtc aagtgagccg ccaagcgcac gttttgtcca
    16741 cgacgaccaa tggcaagaga aagcttgtta tctggaacaa ccaccaaggc acgtttgctg
    16801 tcgttttcat caaagataac ttggtcaacc tcagcaggag cgatggcatt gtagataaat
    16861 tcagctggat ctgctaccca ctcgataaca tcgatatttt cttcgattgg taccatgcgg
    16921 tcatttttag catcgtaacg agctgggtgg aatttgctag taatcttctt gatattagca
    16981 ccaccacgtc caacgattgt accgatagca tccacgtttg gattgtggct acgaacagca
    17041 accttcgtac ggtcacctgc ttcacgagcc acgctcatga tttcaacagt tccatcataa
    17101 acttctggaa tttcttgctc catcaaacgt ttgatcattt ctggatggct acggctaaca
    17161 aagacgttca caccacgagg gttgtcttca accttgtaaa cataaacttc gatacgatca
    17221 tgagaagcaa aaacttctcc aggaatttgg tcttgttttg acaattgggc ttcgatgcta
    17281 ccaaggttga catagataaa gcggttgtca aagcgttcta ctgtaccaga catgatttct
    17341 tgctcatgtt ctttgtaagt attgtaagtg atggcacgtg tttgcttgcg cattttttcc
    17401 atgatggttt gtttggcaga ttgggctgct acacgaccaa actcagctgg tgcttcttca
    17461 aacttgattt tgtctccaag ttcataagct gaattaatgg caagagcatc tttcaagctg
    17521 atttccaaac ggctatcaaa tacttcatca acaacttcac ggacagtata aactgtaaag
    17581 tcacctgttt tttcgttgaa gtcaatagct acgctgtctg actgaccata gcgtctgcga
    17641 taagcggaac gaagcgactc tactactgcg tcgatgatat cttctttttt gattcccttg
    17701 tcttcttcca aaatgcggaa ggcctctagc atttctttac tcatgttttc ttcacttttg
    17761 aatcctcaaa agctatcctt tctttttcta taatttaact gctaaacgtg cttttgatac
    17821 taaactgtat ggaatttgga cggttttctt acgcgtcttg cccatatatt ccatagtcaa
    17881 ctcgtcctct tcgaaggcca acaaggttcc ttcaaagacc ttttgcttat cgatggcttg
    17941 gtagagcccg acatggatgt attttccaac cgctccagcg acggcatcct tggttttcaa
    18001 agggcgttcc aaacctggac tggtaatttc taggaaatat tgttctggga agggatctgg
    18061 cttgatggtg tctaggacag gactgataat ttctgtcaag tctgccgtgt cgttcaaggt
    18121 aattccttcg ggtttatcta caaaaatact gagaatcatg tcactgccaa tctttccata
    18181 ctcgatatcc acgagttcaa aaggagcttc tatgacaggt tctacaactt ctctgactaa
    18241 ttctacgatt gttgcgattg cgtccacctc ctcataagca agaggcgaag atatttcccc
    18301 gcctcacttt tcatattctt actatcagta tagcacgttt gccaacttat gtaaagcaaa
    18361 agcacttgta cagcctaatt ttaggctatc tcttaaaatt ctgcctcaac tcggtagata
    18421 acttgcccct tgtttgagaa tttttgctcg tattctgtca tgacattgcc ttcaaaatca
    18481 ctggcatgca aatctaacca gacaccattg agtttcatgc catattgaga aaagctcact
    18541 aaactgtact caaacaagcc acggttatcc gtcttgaaat gaatttctcc attttcaggc
    18601 aagatacgtt tgaaggtatc caagaaggtc ttgtaggtca aacgacgctt ttcatggcgt
    18661 tttttcggcc atggatctga aaagttcaga tacaagcgat caatctcacc gtcttcaaag
    18721 tagtcagtta agtcagaacc atctacccac aagagcttga tgttaggcac tccaacttca
    18781 agcaccttgt ccaaagcgta gctcaaaaca gacttttgaa tatcaatccc gatatagttg
    18841 atgtcagggt cttgcttggc catacctgaa acaaaggcac cctttccact tccaacttcc
    18901 acatgaatgg gattatcatt gccaaacaag tcccgccatt ttgccttggc ttccaaggga
    18961 ttgaggacca catactgggg atttgcctct agtaattctg ttgccccttt acgatttcta
    19021 actctcatct tctctttcca tacttgtctc ggaaatgacg caaaccatga atctcccgat
    19081 tgacattttc taaatcttgg ttcatataat acttggaaat ctgactcaaa taagacaatt
    19141 gaccatacca atacaattta cttaataccg tttgattgta cttgtaaccg tagtaggtca
    19201 accattcctt ccactgatgt tctgaaatat aatggcagag catatgggcc acatcaaaca
    19261 tgcgatcggt caagcgaacc gaatcccaat ctactaaata aatcaagcca ctatctgtct
    19321 caatccaatt actatgtcgt acatctccat ggacaatggt cgcatggtcc tctctaaatc
    19381 ctggaatagt ctgacgtaaa tcagccatca cttcactgat aaaatgattt ttacgcaaag
    19441 catctggagc cgtttcctgc caagactgta gtaaatctac aggtgtttcc atggcatagc
    19501 ccaaacgact caattgtgtc atcaacggac gtgagcgatg aagacgggtt aaaatattga
    19561 cgatttgctt acgattcata tcataggggg tcaatatctt gcctgtcaac cattcttgag
    19621 cacacatatc acgcccatct gccaaacgac gactccataa taattgtgga gcaatttgtt
    19681 ctctagctag accaggtagg attggagagg tgttcatttt tacaaagatg cgcttcccat
    19741 caggatagct acccatataa gccttgccac ttttcccagg tatgggagtc agtgttagct
    19801 cattatcacc caaatccatt tctttcctcc gtataaagtt tccttactat tctactagtt
    19861 tttggcctat tcgtcaacca ctctaacccg attctcaaag aaaagcctct ggattggctt
    19921 gggtatcatt atagcttgaa aaaggtaagc accgtcttct gcttaccttt tcataatttt
    19981 tataaataat ataagagtgg ccaactgttg taaagcatat ggactagagt agaaacccat
    20041 aggttttgac tctttttata agcaaagccc agcaacaaac ccccaagtag ataaaaaata
    20101 aacgaaggga cattagaagg tccatgcatg aaagaaaaga gagaggaagt tagcacaagc
    20161 cctaaccaag aattgtcaaa aaccgcacct tgaagaagtc ctctgaaaat gagttcctcc
    20221 tggatggggc caaaaactga ggtagtcaaa atcaaagaca gggaaattcc tctgctgact
    20281 tccgccaagt gttggacccc tgagccagaa gaaacagcga agaaatgaat ataaaccagc
    20341 gtctcaagta cacttagaag aaagattgca atgaaaagca aaagttgttt cttgcttaac
    20401 atcccaaaag aaatcatttc aaactttcta gcataagcaa cactcagcga ggttacaaga
    20461 agacttacaa gaatcaatgc agattcattt tgaaaaaaac ccccatggtt aatcgtataa
    20521 ggaactgtaa tgacaattat tagtactaaa aatccaaaac acaaggcatg aaatttatca
    20581 aaaaactcca taaaattatc ctcctcaaca aacagacttc ctacacgtca ttctttagtt
    20641 ctagcctttc caaaacaaac cattttatac tcttcgaaaa tcaaattcaa accacgtcaa
    20701 cgtcgccttg ccgtactcaa gtacagcctg cggctagttt cctagtttgc tctttgattt
    20761 tcattgagta ttagtaacca aaatccgacc acatagccag cccctatgaa tatagccatt
    20821 aaagctagca tggaatttag gaaattaaaa accaccgcag atacaaaggt tagcacaaaa
    20881 acattaaaag caatggtgtc agaagccaag actagaatat agggtgtcaa ccgatctaaa
    20941 gttttggaat ctaggaaaaa taagtgttta tacatgatga cctcctctat ggctgaaaag
    21001 caagcctttt gtttttttac cccaagaccc tatgtagaaa agtgagcaaa aacgggaagg
    21061 tcgctacaat attattgatc acatgcaccg cataggatgg ataaatgctc ttggtatagc
    21121 gggtcaaacc agcaaagatg attccaactg ttgcaaagac gaagatatct aacagactag
    21181 gcaggcttga aaaatgaggg agagcaaata aaatagaagg aagaagcaaa tcaagaccaa
    21241 atcgcgaatg cttaaagaaa gcatgttgca gtaatcctct ataaatcaat tcttccatca
    21301 gtggaaccag aaagaacagg gctatataaa tacctagctc tgcaaagtta gtcccactat
    21361 aaccaatcaa tacagcccaa ccttccgcag ttgactgaac atgtttagct gtctgaacgt
    21421 taaaagagat ctggaacact accactaata ctgtcaaaat cgaataccaa agccattttt
    21481 ttcttggaat gcggaagaga taaccatggc ctgtcttaac aagaaccaca atcatgactc
    21541 caataaaaag taaactcaag atattttgaa tccagaataa attgcctatc tgagaagaaa
    21601 attgccaata gttttggacg ataagcgtca gctgagaaag accaaatacg aaaaataagt
    21661 aagagaagac tgcacttatt ttgaatagaa gttgatactt tttcatagaa atcctcccta
    21721 ctataacctc accttgtcag gctctactgc tgtaagatta agaagacagt ttgttttttt
    21781 taaggctaac ctgactacta gataatagat acattaaggc attaaagaca atgaaaatat
    21841 gtccatagaa taaaatcaac ctcgcatcca aaccaagata aagtttgatt atcaaaaaga
    21901 tgagcaaaag aatttgaaac cataaggttt ttccaaaaat aaatttaaag cgatttcgaa
    21961 tatctacttc cttgattttt accgccaccc ctttattagc aagaaggaaa actcctgctt
    22021 caaacaaacc actgtaaaga acaagccacc caatagatac gatagagatt tgtaaaaatg
    22081 tccctaaaag aatatccaac acactactca agaaaataac aaaaaataat ctgtatttca
    22141 tattaaatac ctccattcat ttatttcact aacaatttaa tagagccttc tactcaaata
    22201 tcctgtcaga aaaggataga aagctacttt ttataatact tcaagcccca catgagcaga
    22261 agcgtgataa acaagcagag aatacaccta tataagcgat tagttgttga tagaattctg
    22321 tttctgaaat acctctatac aaacaaatga caaacataaa atctgccaag ccgataaaca
    22381 taagttgatt ggttctagga ctaaccaaat catcatttac ttatatttaa gagtatctct
    22441 tttatgttag tgtatgttaa cactaaaaaa caagttaggc caataatatt taaaatgaac
    22501 aataacgggg ttaagtctct aaaaaaatta tctactgaca ctacaagaaa tactatacat
    22561 attatagtcg aaactatctt tttcttatcc ataattattt actcctttcc taacaaatcc
    22621 aacttatcaa tcaagagcga tttttaacat aatgtagcag cacccgttgc aactttgaca
    22681 agtttagtat atcattgttt tttaaaattt ttcatccaaa tcttgaattg tcatcgaaac
    22741 ctcctaaatt gcaaaaactt cattagcccc tactttttat aatacttcaa accccaaatg
    22801 agtagaagca tgatgatcaa gcaaagaata gcaccaatat aagcgattag ttgttgataa
    22861 gattctcctg ctgtgatacc tctatacaaa caaataatag acataaagcc tgtcaagccg
    22921 ataaacatga gttgattggt tctaggacta accaaatcat cgtcttcaaa ctcttttatc
    22981 cgcatttccc tagtgaggta aacagtgacc aaaatagaag ctaagttaat aaccactaaa
    23041 agaaattgga aaactgacga aatagaaata gataagtaga aacaagcaaa ggcaactgcc
    23101 ccaggaacaa tctcacaaag aatatgattc tttttaatca agaaaatctt tcatttcttt
    23161 tctttctttt taattaaaga aaaatagatc ataaccgcaa tcatataggc tatggtataa
    23221 aatagattat accaaatact ctccctaagc ggataaagaa agatggacat gatcagatac
    23281 agaacgaaaa taatcagtat ttttttcttc ataagatttc ctcctaaatg tgcgatttat
    23341 cttagttgag caagaacatt tacactgcta gtatagcact tattttgacc ttggatcact
    23401 caaatcataa atggtcatca aaacctcttg aattgtaaaa attaaaaaaa gcaagcatga
    23461 aaaacatact ttcctcttta tgttgtattg ataccaactt gtttgtagac ttttcatcct
    23521 gctatcacat atcattttga caggcgaaac aatattaaag aaactcccct gtaaattaag
    23581 ctagcaaata caggggagaa atttattttt tagagagtac tatccgtatc ctttttggaa
    23641 gattttgaaa atatttttct aattaagtca tccatataag gaccaaatat accaactact
    23701 aaaccaataa taaaactttt aaaatccata attaccacca acatgttgct acataggcta
    23761 cacctccaag tatagctcca cctgcagcac cagttacacc tattcctata gcaaatggtc
    23821 ccaatagaaa tgtcaaaccg ttgttgcaca cccatcaatt gcgccatatg caacccctgc
    23881 tgcacaacta atttttcttc cccaatcaat atctccacct tcaacgcaag caagcatttc
    23941 attatccata acagaaaatt gtgacatcat ttttgtattc atatagtatg tcacttttca
    24001 gttacggaac aagtttaata taaaaattat caaaaaaaca taggcaataa agagaaaaat
    24061 taatttatca tagattagaa ataatatgac aaaacaattc aatgatgtta attcaatagt
    24121 cttttgtttt ttatcagaga tacttatgga tagataaata agataggttt gaaaagcgaa
    24181 gagaataata aagaatatag ccttcataaa atttagcttt catttttatg atgtagcggt
    24241 ataggctaaa tatccacaaa ccactgctcc tccaattcct cctattgcag cgccccatgg
    24301 tcctagaatt ttcccatatt tcactccacc cgctgcacaa cctaaagcag caactacagc
    24361 tgctcctccg gaattacctc cataaacctc actcagcatt gtttcattta tattacaata
    24421 agtattcata caagtctcct tttattaaaa tccacccgtt gcccctgtta ctcctgccca
    24481 aagatccaca ccaaatttag ctcctatgta tccacatgct cccataaatg gtgctccaac
    24541 accactcgca gcacaaatag ctgtccctag cccccagcca ccaaaagcag caccaccacc
    24601 ttctaagaca ttagtttgcc aattattctt gcctccttca atactagata acatagttat
    24661 atccatttca tgaaattgtt ccatcatttt tgtattcatg acaaatactc ttttttattt
    24721 ttaatttttg tcttgttgta actttgacaa gtttagtata tcatcgtttt ttaaaatttt
    24781 tcatccagat cttgaatagt catcgaaacg tcttgaatta gcttttcatt tgaaaccacc
    24841 tctaaatttt ttaaaaaaag ataatttcta attatttttt accattcagg aagtttcaat
    24901 gactattcaa gatttaataa aatatgaact tatttttatg gcataatata cctatctact
    24961 atatgaaagg aattgccaat gacttcttat aaacgtacat ttgttcctca aatagatgcg
    25021 agagactgcg gtgttgctgc cttagcctcg attgctaaat tctatggttc agatttttct
    25081 ctagctcact tgagagaact tgcaaagacc aataaagaag ggacgactgc tcttggcatt
    25141 gtaaaagccg ctgatgaaat gggctttgaa acaagacctg ttcaagcaga taaaacgctc
    25201 tttgacatga gtgatgtccc ctatccattt atcgttcacg ttaacaaaga aggaaaactc
    25261 caacattact atgttgtcta tcaaacaaag aaagactatc tgattattgg tgatcctgac
    25321 ccttctgtaa aaatcactaa aatgtcaaaa gaacgctttt tctctgaatg gactggagta
    25381 gctatttttc tagctcccaa acccagctat caaccccata aagataaaaa gaatggtcta
    25441 ctaagcttcc ttcctctgat tttcaaacaa aaatctctca ttgcttacat tgttctctca
    25501 agcttattgg tcactattat caatatcggt ggttcttatt atctccaagg aatcttagat
    25561 gaatacatcc caaatcagat gaaatcaact ttaggaatca tctcagttgg tctggttatc
    25621 acctatatcc tccaacaagt catgagcttc tccagagatt aagcattgat gtgattttat
    25681 cctatattcg ccatattttt gaacttccca tgtctttctt tgcgacacgt cgtacaggag
    25741 aaatcatttc acggttcaca gatgctaact ctattataga tgccttggct tctaccattc
    25801 tttctctttt tctggatgtt tctattctga ttcttgtagg gggcgtctta ctggcacaaa
    25861 accctaatct cttcctcctt tctcttcttt ccattcctat atacatgttc atcatctttt
    25921 cttttatgaa acctttcgaa aaaatgaacc atgatgtcat gcaaagtaat tctatggtta
    25981 gctctgccat tatcgaagat atcaacggga ttgaaactat aaagtcgctc acgagtgaag
    26041 aaaatcgcta tcaaaatata gacagcgaat ttgtagatta tttggaaaaa tcctttaagc
    26101 tcagtaaata ttctatttta caaacgagtt taaagcaggg aacaaaatta gttctgaata
    26161 tccttatcct atggtttggc gctcaattag tcatgtcaag taaaatttct atcggtcagc
    26221 tgattacctt taacacactt ttttcttact ttacaactcc tatggaaaat attatcaacc
    26281 tccaaaccaa actccaatct gcgaaggtcg ctaataaccg tttgaacgaa gtctatctag
    26341 tcgaatctga atttcaagtt caagaaaacc ctgttcattc acattttttg atgggcgata
    26401 ttgaatttga tgacctttct tataagtatg gttttggacg agatacctta acagatatta
    26461 atctcacgat taaacaagga gataaggtta gcctagttgg agttagtggt tctggtaaaa
    26521 caactttagc caaaatgatt gtcaatttct ttgaacccta caaagggcat atttccatca
    26581 atcatcagga tattaaaaac attgataaaa aagtcttgcg ccgtcatatt aattacctac
    26641 cccaacaagc ctatatcttt aatggctcta ttttggaaaa cttaaccttg ggcggtaatc
    26701 atatgattag tcaagaagat attctaaaag cttgtgaagt agctgaaatc cgtcaagaca
    26761 ttgaaagaat gcctatgggc tatcaaactc agctctctga tggagctggt ctatcaggag
    26821 gacagaagca acgaatcgct ctcgctcgtg ctcttttaac taaatctcct gttttaatac
    26881 tagatgaagc tactagcggt cttgatgtct tgactgagaa aaaagttata gataatctta
    26941 tgtccctaac tgataaaacc attctctttg tagcccatcg tctcagtata gccgaacgaa
    27001 ccaaccgtgt cattgttctt gaccagggga aaatcattga agttggtagc caccaagagt
    27061 taatgcaggc gcaaggtttc taccatcatc tattcaataa ataaggagaa tgtcatgaat
    27121 cctaatcttt ttagaagcgt cgagttttat cagagacgtt accataacta tgcgacagtg
    27181 ttaattatac ctctttcatt actatttact ttcatcttga ttttctccct tgttgccaca
    27241 aaagaaatta ctgtcacttc ccaaggagaa atcgccccta caagtgtcat ttcatctatt
    27301 cagtcaacca gtgataatcc tatccttgct aatcatttag tggcaaatca agtagttgaa
    27361 aaaggggact tactcatcaa atactctgaa acaatggaag aaagtcagaa aactgcctta
    27421 gcaactcaat tacaaagact tgagaagcaa aaagaaggac ttggaatttt caaacaaagc
    27481 ttagaaaaag cgactgatct tttttctggc gaggatgaat ttggctacca taataccttt
    27541 atgaatttta ctaaacaatc ccatgatatt gaactgggta tctcaaagac taacactgaa
    27601 gtttcaaatc aagctaatct taccaatagc agttcatcag ccatcgaaca agaaattaca
    27661 aaagttcaac aacaaattgg agaatatcaa gagctgagag atgctatcgt aaataaaaga
    27721 gctcgcttac caactggcaa tccgcaccag tcaattttaa atcgttatct tatagcctct
    27781 caagaacaaa cacaaggaac ggcagaggag ccatttttat ctcaaattaa tcaaagtatt
    27841 gcaggtctgg aatcatctat cgcaagcctc aaaattcagc aagctggtat cggaagtgta
    27901 gcaacttatg ataatagttt agcaaccaaa attgaagtac tccgcactca gtttttacaa
    27961 acagcctcac agcaacaact aaccgtggag aatcaattaa cagaattaaa agtacaacta
    28021 gatcaagcga cacagcgctt agaaaataat accttaaccg ctccaagtaa aggtatcgtt
    28081 catctgaaca gcgaatttga aggtaaaaat agaattccaa ctggtacaga aattgctcaa
    28141 atattccctg tcatcacaga tacaagagaa gtactaatca cttactacgt atcttctgac
    28201 tatctacctc tactagataa aggacaaact gtaagattaa aactggagaa gattggaaat
    28261 cacggcacca ccatcatcgg ccaacttcag acaattgatc aaactcctac cagaacagag
    28321 caaggaaatc tctttaaatt aaccgctctt gcaaaactat ctaacgagga tagtaaactc
    28381 atccaatatg gcttacaagg tcgcgtcact agtgtaacta caaagaaaac atattttgat
    28441 tatttcaaag ataaaatttt aacccattct gattaatttt cagataacac tctataacta
    28501 tttattatct tatcaaaaag gagaatcata acatggataa gaaacaaaac ctaacttcat
    28561 ttcaagaact aacaactacc gaactcaacc aaattatagg tggaggatgg tgggaagatt
    28621 tcttatatag atttaatata attgaacaaa aaaatacaaa aggatttcat cagccaatac
    28681 aactataaaa aaacaagacc aagagaacgc actctcggtc ttattttttc ttcattctat
    28741 atgtattaca gtaagtacct gacgaaaaac gtgatcttgg caggtggtat tgagactggt
    28801 attgggatga ctttccacaa ttttcataac ggtatagaga ccaactcctc tctcctcccc
    28861 tttagaactt gctccaaagg agaagatttc agaaatatcg attccctctt ctttgatgga
    28921 attttcaatg ataaaggtct cctgtgctcc atttttaaaa aaggcaattg aaacatgagg
    28981 ttgacaggct tctacactag cttcaatagc gttgtcacaa aggatagaca caacggttag
    29041 aaaatcaagt agactcatcc cctctacctg aatctcctct ggaacttcga cattaaagac
    29101 aatgttctta tctctagctt ttataaattt tccagctagg agacttttga gggcacgatc
    29161 ccgaacattc accaatcggc caaggtcata tttattgtcc tgcaatttct gactggaatc
    29221 ccttaagacc gagtcgtaga tctcttttat ctgctccata tcctcctctt caatgcccaa
    29281 acgtaagctg gttaagaggt tagtgtagtc atggcgaaaa ctccgaattt ccttgtaaag
    29341 ttcctctata tgccgactat agcgttccat atctctgtag cgcaaggtct gctcttggtt
    29401 cagttcctcc tgaagttttt ccttcaaata ggtatccaat ttcttgatac cccccataaa
    29461 aaagagtagg taaaacacta ggatgagatg gcgaacagtc gttgattgaa taccttgttc
    29521 atattcaagg taagatagac tttgcatcac tagataataa gcccccattg cccagttaat
    29581 cttagtaaga gacttttgaa aacctgtatc tagaaactcc cttctcaatc tagtgaaatc
    29641 atagtctaac catttcaaaa agactaaaac tatgaagcaa acgaatatca taatcaataa
    29701 aaagatagga ttgccatccc catctacaat tccttgcccc aaaaatggaa gcacaaaata
    29761 ggaaacacct ctgtaaaaga gctctactaa tatcattggg aagagaccat aaaaaataag
    29821 gattttttta ggaagccctc ttaacaataa gaaagataga cctataccga acaaaggttc
    29881 tataaaatag gacaaatatt tacttacagc caaaaattga aaagtcgtaa aaatgatccc
    29941 tagaagaaat ttcagaagaa aggccttaaa aatcctctcg aaagtaagat caattccatc
    30001 caccttaaag aagatgacaa tttctagtcc attagtaaca agtgtataca acaatatcca
    30061 agcaatgttc ataaattctc ctagctcagt gtaatttatt gatggcctca gacacttccc
    30121 tgaccttata acgggcgatt agacaacttc caccattggg aaagaaaagc agtttttctt
    30181 tcttatccaa atgcaccaca tttgcaggat tgatgagaaa agagcggtgg cactgcaaga
    30241 gacggggctc ctgcttgaaa acctcctcta aactcgctgt aaattccagc ctgtctgtct
    30301 tggtatagag aataacacga tgggctctgg gcgacgtttc gagatagtaa acctctttaa
    30361 aaggatactg aaattgggca aattttgatt taaagtaaaa gcaatcttcc gccagacttt
    30421 tactatcttg actattggca tagaggaggg ctgtctcgat ccgagattca aactcctctg
    30481 ctgacaaggc cttatcaatg tagtccaaag cagacacttg gtagcgaaaa gacaggggca
    30541 taaactccga gtgagtcgtc acaaagacaa tcagggcata aggatcccga tcccgaatct
    30601 ttctagccac ttccagtccc ttcatctctt catttcgaat ctcaatatcc aaaaagaata
    30661 gctgatgggc ccccttctca tgcacttcag ccagcagttg gtccggcttg ccaaatacct
    30721 caaaagagct aggaatgata tgatgtgctt tcaaaagttt ctcaatcgtc gtttcaattc
    30781 tagtctgttg ggaaaaatca tcctctaaaa caaatattct catcttctta ctctccctct
    30841 ttcaaccatt tttgacgaat ttctctatag cgacgtctgg catacttgac agcgtattga
    30901 ccttcttctc cgagaaaaag gattctttct tgaaaatcaa tcgattttaa tttatcaaga
    30961 ttaaccaaac aatttcgatg acatctcatc aaggtttccc cacattggtt ctcaagatta
    31021 cttaaatttt gaagcatatt aaaactagct tcttctgtaa caatctgtac ggtatgggct
    31081 ttagttggat gtgtttggat atagtagata tcgtcgatgt ttactttata gactgttttc
    31141 tgcgtctgaa taatcatata tttcattgga ttctcctcct aagaaaagaa taacagaaaa
    31201 ggtctagccc aagcacaccc aatcctaaac agtctttgaa aactcctaaa aggattattt
    31261 tctacaacat catgatgagc ttacaactat tttatcataa aattcactca gcgcaattca
    31321 agacatttca atgacaatta aagatttgaa taaaaaaaaa gaattaaaag tgataaacta
    31381 acagtatcaa aacacagttg ccagaagtaa gactggcacc cagattaaag gaggcattcc
    31441 catgacagat acagacccca tcaaaagagc tcatactttg attactgact taaacaaagc
    31501 ctaccaagca tgcaaacagg caagcgctga cgacgtccgc tttcaggagc aattaaactc
    31561 tattcttggt tttctagcca aggctgaaac agtggataat cgattcttga ttgaactaga
    31621 aaaattttac cagacttcca gtcttctcat gggactcagc gctcttgatc cagatgctcc
    31681 aactcgcgcc gcttggcggg cctatgaccg cttccacttt gaccaagtca agaccaagtt
    31741 aatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaagctgt acttgagtac
    31801 ggtaagacga cgctgacgtg gtttgaagag attttcgaag agtataagtc tctacggacc
    31861 aaccattatc ctgtagtaac aaaaaagaag ttgagacaga ctgaactcaa cttctttttt
    31921 agtgtcgtat cagcaatgtt agtcctgcat ctgacgtttt acctgataag gcaaatacaa
    31981 gactagtaaa accaaaccag ctcctagtaa ggctagaagg gctagttttt cttggaaggt
    32041 aatcaaccca acaactaatt ccacaagtaa aacaaaactg gtcaatcctc gaactacctc
    32101 ctgtaagcct ttttcctttt gccccttgtc cagcggaaag agttgggtca aatactggta
    32161 gtcaaaggca tgatagaggg ccagcaactg gaagagcaag aggtagttaa agagaactac
    32221 cactgctgtc gcaatccaag cttgctcgat aaaaacctgc gccagtacgg aaagtaagag
    32281 aagacgaaga ctgagagcaa agaggtcgcc atttcgcaga taagaacgca gatagagatt
    32341 ttgccaaatc ttcccaggca ccttctgaac agcctttaag ataaagtcca gataggcacg
    32401 acgcttaacg ctgtttgaaa ttcccttgac ctgcgtaaag agggcaaaga aacgaagcaa
    32461 gacttgctta cgcttgcttt cttgggaaat gacatagtcc cagtccagcc cagtttcagt
    32521 gaaaaatttg ctggcctttt gacgaaagtg gaaatatttt cctaccccca ataaaagcac
    32581 atagagcaga aaaactggca agccataacc cattgctaaa aataaaggcg caaataacag
    32641 caagaaaagg gtctgtacaa agagccaaaa gactagggaa atgccagttt gacgcttgag
    32701 atggagcttg atttcctctt ctccaactaa gagaaagagc ttgtctggag cctccatata
    32761 ggtggcaatt cctccccaaa gtaaaagtaa aacagacgta attcctacaa acaaaaggat
    32821 aggccaatga ttttcaggaa aatgttgtaa gagttgactg tactggtagg ctagaaagcc
    32881 caacaggaca agcaggaaca agacaaagtg gtcattgagc acatagcgca gataaccaag
    32941 acactcctta cgaaaggcct gctttctctt taaaaacaag tctttcatag atcctcctct
    33001 ttggtcagag ccaagtaaat atcattcaaa ctagcctcag gcatatcaaa ggcttcacgt
    33061 agttgcagga gattgccttt ggcacgcacc tctcccttgt gaagaatgac aaaggcatca
    33121 cacatcttct ccgccgaatc cagcacgtgg gtactcatga gaatagactt gcccttttgc
    33181 ttctccactt ccaaaagctg aatcaaatca gaaatagcca gcggatcaag accaaggaaa
    33241 ggctcatcca cgatgaaaag acttggatcc accacaaaag cacagataat catgaccttc
    33301 tgcttcatcc cttttgaaaa atgaacaggg aaccagtcta atttctgttc caaacggaac
    33361 atttttaaca agggctctac tcgttcgaaa gccacttttt gctcaatacc gtaagccata
    33421 gcaaccgttt cgatatgctc tctgagggtc aattcctcat acagactagg cgtctcagga
    33481 atgtagccaa tctgcttgcg gtagctagtc gcatctcctt gcagagtcag gccattgata
    33541 ttgatggagc cactataagg tgccaacaga ccgataatct cattgatcgt cgttgatttc
    33601 ccagcaccat tgagaccaat caaaccgacc aactgcccac tttcaacagt aaaggacaca
    33661 tctttcaaaa caggaacatg aacatagcca cctgtcaggt ttttaatttc taacatattt
    33721 tctccaaatc tggtataatg tagctatatt atatcaaaat tcagtacagt agaggtagat
    33781 tttatgtcag attgcatttt ttgtaaaatc atcgcagggg aaattcctgc ttcaaaagta
    33841 tatgaagatg agcaggtcct tgcctttctt gatatctctc aagtaacact aggacacacc
    33901 ttggtcgtgc caaaagaaca ctatcgcaat cttttggaga tggatgctac gagcgccagc
    33961 caactctttg cccaagtacc aaaagtagct caaaaagtca tgaaagtcac taaggctgct
    34021 ggtatgaata tcatttccaa ctgtgaagaa gtcgctggtc aaacagtttt tcatactcac
    34081 gttcaccttg tgcctcgcta cagtgctgac gatgacctca agattgattt tatcgcccac
    34141 gaaccagact ttgacaaact tgctcaagtc gctgaaacca tcaaaaacgc ttaaggagtt
    34201 gctatgaaat tatccaacct actgctattt gcaggagctg cagccggaag ttatctggtt
    34261 acaaaaaatc gccaaaccat cacagatgaa gtcttgaata ccactgaccg cgttcaagct
    34321 atcaaggacg atgtggatat tatccaaaac agcctgcaaa tcattaacca gcaaaaagaa
    34381 cttatcaagg aataccaaga agacttgact tacaagttta aggtcttgga aaaggatatc
    34441 cagactagac tagctgtgat aaaagaaatg cagggaactg aagataagta aaaagagccc
    34501 gacggctctt ttttaaaacg taaacaagtt atagtgaatt gaatttagaa tagcacatca
    34561 tagtttctaa agcattgtta gagattactt taaaatcctc ttatcaattt gttcatattc
    34621 tatttcaatc tactatatat atcccatcaa ctatgcatca taatttaggt aactcatact
    34681 caataaaaat caaaaagcaa actagaaagc taggcacaga ctgctcaaaa caccgtttta
    34741 aggttgtgga tagaactgac gaagtcagct caaaacactg ttttgaggtt gtggatagaa
    34801 ctgacgaagt cagtaaccat acccatgaca agccgacgct gacgtggttt gaagaaattt
    34861 ttgaagagta tcattcacca tttcacaact aaatcgaaga ctttctgccg taatgaaaac
    34921 acctgaaaca gcttggtttc agctgtccgg aaactttaag acttaggttc aaagtttagg
    34981 tatggaactt cgaaggaggt cgctaccgtc cgtcattact taggaaagtc ttaaaaaatc
    35041 tataaagtaa aaagagcccg acagctcttt ttgtttatac tcaatgaaaa tcaaaaagca
    35101 aactaggaaa ctagccacgg gctgctcaaa acactgtttt gaggttgtag atacgactca
    35161 catatatacg gcaaggcaac gctgacgtgg tttgaagaga ttttcgaaga gtattattct
    35221 ccatcaaagg catcttttat atggtcaaag aagccttttt tctttggatt tactttcaag
    35281 tcaccagcag tcgcgaattc tttcaaggct actttttggc ggtcgttcaa gcctgtcggt
    35341 gttacgacat taacagtaac gtattggtca ccaactgcac cgccacgaag gctcggtgcc
    35401 cccttactac gtaggcggaa tttcttacca gtctgagttc cctctggaat aaccaattca
    35461 acatcaccgt gaacagttgg aatatctact gtatcaccaa gagccgcttg gacaaagttg
    35521 aggttgagat tgtagaagat agtcgttcct tcacgttcaa acttgtcgct agcttctaca
    35581 gaaactacta catacaagtc accataaggt ccaccgttaa agcctgcttc accttgacca
    35641 gcgaggcgaa tttgttgacc tgtttccaca ccagcaggga ttttcacatg tacgctatga
    35701 gcttgtttct catgacctgt tccatgacag gttgtacatg gatatttgat ttcttttcct
    35761 cgaccgtgac agacatcaca ggttacttgg cgacgcatca taccaagagg agtctgcgta
    35821 tcgacgttaa tgacaccagc gccatgacag cgtccacaag tgactggact tgtccctggc
    35881 ttagcaccag agccattaca tgtacgacag ccagcttcac gatgatactt aacttccttc
    35941 tcagttccga agatagcttc ttcaaaggtc aaattgacac gatactggag atcatctcct
    36001 tggcgaggag cgtttggatt gcgcgaagaa ccgcctccgc cgaagaaact tgagaaaata
    36061 tcctcaaaac caccgaagcc acctgcccca ttgaaaccac cgaaaccacc agctccacca
    36121 aaaccaccat tggcgcctgc agcaccatac tggtcatagg cagcacgttt ttggtcgtca
    36181 ctcaaagtct cataggcttc ttgaacttcc ttgtacttgt cctcagcacc aggctccttg
    36241 ttgatatctg ggtgatattt tttggaaagc ttacgataag cctttttgat ttcgtctgcc
    36301 gaagcgtttt tggatacccc cagacgatca taaaattcag tattgttcat acaagatacc
    36361 aagaccgtaa aattcgactg aaaaatagga aatctgacgc tggagcgacg ctcctagaca
    36421 gatttctctt ttttccgaga atttaggtcg ggttcaattc ctttctttta tattgatgag
    36481 ataatactcc agccactcgg ccctatccct ttttaccgaa aaacagaggc tgggttgcaa
    36541 cctctgtggt tagattattc atttgaaata aaaatggttg tattatctct agtagtaatc
    36601 ttcaaagacc ttttagctaa atcaaactca aatttattat agtgtgggtc ttgtgtttta
    36661 tataggtgta actcctgaca tatatgatcc gaaaagtaaa tcataacatc tttaaacaca
    36721 gaagtgtggt catatttact cttaccaaca gctacttctg taaattcttt ataaatgaca
    36781 tttccatttc tttccacagt caccagcatt tctgttggat tataatccaa attaaataat
    36841 tattcaaaaa aactttatct tttcatgata atctgcaatg tcagaaagat tatttttatt
    36901 aacactcata acactagccc cttatttttc agtaaactct ccgtctacga cgtcatcgcc
    36961 tgcgtttcct gttgcttgtg cgccttctgc tccttcttga gcttgttgcg ctgctgcggc
    37021 ttgttcgtag agtttcacag caaggccttg agctttttcg ttcaacgctt caagtttcgc
    37081 tttcatgtcg tccaagttgt tgtcttcttg agctttctta aggtcatcaa gggcagcttg
    37141 ggcagcgtca cgttctgcgt cgaagccttt accttcagtt tccttgattg tcttttcagt
    37201 cgcaaagatt gcttggtcta cttcattacg aaggtctact tcttctttac gtttcttatc
    37261 ggcttcagcg tttgcttctg catctttcat catgcggtcg atttcttcgt cagtcaaacc
    37321 tgagttcgat tggatgacaa tagtttgttc tttttgagtt ccaaggtctt tggccttaac
    37381 agacacgata ccgttcttgt cgatgtcaaa tgttacttcg atttgaggaa ttccacgagg
    37441 tgcagctggg atatcagtca attggaagcg tccaagagtc ttgttatctg ctgccattgg
    37501 gcgttcacct tgaagaacgt ggatatcaac ggctggttgg ttgtctgctg ctgttgagaa
    37561 gacttgtgat ttagatgttg ggattgtagt gttgcgatcg ataagttttg taaatactcc
    37621 acccattgtt tcgataccaa gtgacaatgg cgttacatca agaaggacaa cgtccttgac
    37681 atcaccagta atcacaccac cttggatagc cgcacccata gcaactactt catcagggtt
    37741 tactgatttg tttggttctt taccagtttc agctttaaca gcttcaacaa cggcagggat
    37801 acgagttgaa ccaccaacaa ggataacttc gtcgatttct gacaagctca aacctgcatc
    37861 tgaaagggct tgacgaactg gaacttttgt acgttcaaca aggtcacgag tcaaatcatc
    37921 aaatttcgca cgagtcaaag tcatttccaa gtgaagaggt ccagcctcac ctgcagtgat
    37981 aaatggcaag ctgatttgtg ttgaagttac accagaaagg tctttcttcg ctttttcagc
    38041 cgcatctttc aaacgttgca ttgccatctt gtcagtagac aagtcgatac cgttttcttt
    38101 cttgaattct gctaccaagt ggtcaatgat tttttggtca aagtcgtcac caccaagttt
    38161 gttgtcccct gcagttgaca atacgtcgaa gacaccgtca cccaattcaa ggatagagac
    38221 gtcgaatgta ccaccaccaa ggtcaaatac caagattttt tcttctttgt cagtcttgtc
    38281 caaaccataa gcaagagctg ctgcagttgg ttcgttaaca atacgttcta cttcaagacc
    38341 agcaatttta ccagcatctt ttgttgcttg acgttgagcg tcgttgaagt aagccggaac
    38401 tgtgataaca gctttggtta ctttctcacc aaggtagtct tcagcgtagc ctttcaagta
    38461 ttgaaggatc atagctgaga tttcttgtgg agtgtattct tttccatttg cagaaacttt
    38521 ttcagaagtt cccatcttag atttgataga gataactgta tctgggtttg tgactgcttg
    38581 acgttttgca gcatcaccaa cgatgatttc tccgtttttg aatgagacta cagatggagt
    38641 tgtgcggttt ccttctgggt ttgcgatgat tttgctttca gttccttcaa gaactgcaac
    38701 tgctgagttt gttgtaccta agtcaatacc gataatttta gacatgtgtt tttctccttg
    38761 ttagttaatt ttctattttt ctttttgata ctcttcttaa gtggcgacgc cgtcagagct
    38821 tgacttcgtc aatctctttg actaaacttt gagcctaagg tctcaaaatt tgcgcaaata
    38881 gcaccacggc gaagagtatc gtctttggtt cgcttcgctc actattacaa agccaaacat
    38941 attttatctt tcttcatagt ttattgtcgt ttcggacaag ttttctatta tgtaaattgc
    39001 gacacgagga gtcgaaatcg attttatttc gacgacgagt tagtaaggaa gctaggcaaa
    39061 cgtcatagcg attgccgttt tctgacgagt tgctttagct accgtcagaa ttgccgaatc
    39121 gaacacgccc taagctctga gtaaaaaaga tagattttct tgtgttcatc gaacacttcg
    39181 tcaatctcct atttttactg cgagcttttt acgagctttg tatcttagtt atacaccact
    39241 accattgctg ggcgtaggat gcggtcatgg agtttgtagc ctttttgaaa gacttgggcg
    39301 atggtatcta ctgggtgttc atcgtctgct gggagagttt ggatggccat atggtagtta
    39361 tggtcaaatt cgccatctgc tgcgatttct tcaattcctt cttctttcaa agcgtgaatc
    39421 aagctttctt gcaccatcgc caagcccttc ttcacatcat ctgtcaaacc ttcaactgca
    39481 agtgcacgct caaggttgtc aagagatggt aagattgctt ttgccaagtc ctggctacga
    39541 taacgttgca agttttgacg ttcttcattg gcacggcgtt ggatattttg catttctgca
    39601 tgagcgcgaa gatatttgtt ttcgaactca tctgcacgtt catttgccaa gtccaactca
    39661 gacttttcag gagttgtttc ttcagctgtt tccacaactt cctcttcttg aacttcttct
    39721 acttcttcat tttttatatc ttgggccatg ttcgcctcct ttaatgattt caatcttaat
    39781 gtacttcgta atgattactg ctgaggtagc ggtaaaaatc tgtcaacttc atggtcaaaa
    39841 cacggttgac cacattgact tgattgatta gctgttggta atccagatta actggaccga
    39901 taatggctag aattccaact cctcgataag gaatgaggaa cttactacta atcaccgcta
    39961 ggtcagctaa acaggactct tgaccgtctg caacacgaac attttgcatc tgatcctcac
    40021 gcaacccctc acgaatctcc aaggccacct tttgcggttg gtcaaagaac tgataggctt
    40081 ctagattggc aaaattcaag agattgacct tgcccgccat cacaatgttt tcgttgaaca
    40141 tttccttaaa gatgtgttca aagagatcga tgacattatc cgttgttgta aagtaacgct
    40201 ggataatctg cggaatctcc gtccgaatct tgtagtgaat atctaaaacg gtgtgaccga
    40261 ggaaacgttc ctgaatgatg ctcttcagtt tcagcaaatc ctcctgcaag aagttccttg
    40321 gaatcagaaa ctgactagta accgttcgcg actcgtctag ggtaaatacc gccaaggctg
    40381 tatgttgccc caaaacaacg atatcaaagg ctgtcaaacg ttgcctgctc ggctcaacat
    40441 ccagtgccac taccgtacag ccactcaggt ctgttagcaa gttagcagcc tcttgcagaa
    40501 tatcctccaa tttgaagaat tcctgatcaa aggctttgac aatctcatat acctcatttt
    40561 cagccagccg gtgaaaatcc agtgagtgtt tcacatagta ctgaaaacca gcaacacttg
    40621 gcatccgacc gcttgaagta tgagccttct caagcaaccc ttgtttttct agttccgcca
    40681 tgtcattacg aatggttgca ctgctagagt taatagactc ttgcaaggct tttgatccga
    40741 caggttcgtg cgttttggta aagatgtcaa taatcagatt taaaatatcc tgctgacgct
    40801 ctgtaaccat ctcatcactc ctctctgtct gatcaattag cactcaatgc atccaagtgc
    40861 taacttatga ttctattata cacccttaaa agagaatgtc aagacaaaaa ctcaaaaaat
    40921 tagcactctt ttatcaagag tgctaaaaat caatctgaag acctagaacc ttgctattca
    40981 tctactcgat atttcctttt tagtctgaaa taaccatgaa ttagataaga aatcagaaaa
    41041 gcatataaaa caaaaataag aaagaaagac atagaaagat cctctctaaa caaactcgta
    41101 caaacaacaa gaccacctaa gaaagtagtt gtacaggaac gaagtctaga tcgcataact
    41161 tcccatttga gccccttact catatagact tgatcctctg gaagtaaatc agaagacgat
    41221 ttacgaagaa tcgaacaaga acctgctcct atcaattccc aacctctatc tctaaaatct
    41281 tgcagttcat gcttatattt tttaagaaat ctagaatcat agatacggta gatgacatcg
    41341 tctggttgac attggtcaaa atagaacaaa ccaaaacgac tcgttctata cctccaacct
    41401 ttcaaatgca tctcatgtaa atattcttct tacttgtcca aatcaacaat ggtgaaaatc
    41461 cgaaattcta ctctgctatt cattgtctta ccccaaaatt agaaaacatg cctggcgtta
    41521 tttattagat aattctttcc acttttgact caatctccaa aaaatataag aaatctgaat
    41581 cgcaaaaact ataaataaaa cccaatctat tatgaaaatc aaaaacactt tccaactgaa
    41641 agaactacct ccagtgacaa actttgagaa aaacggtagt agagctaaaa agagaagtaa
    41701 aataggaagc atccgcattg ttaaaatccg tttggcataa aaaaatcttt atttaaacta
    41761 aaatattata tcaaaattta cgccagtttt tgaacggctg atgtagatat tttatacttt
    41821 caaaatgttt aaatgtgatt atttattttt gaaaaatagc tcaccagccc gactgaaagt
    41881 gcttatagaa tgataataag tcgcctgccg aaaacagcgg aaaatagcgg tgttatgcgg
    41941 agataatctg acgcgatgcg aaagtatatt gcatacttat tttcaacaat ttagcagagt
    42001 atttttataa gtgtgatata atagaagtat aatttgttct gatagtttat tttatggaga
    42061 agtagatttt tagaatgcgg agggttcaat atggttgagt ttataaagtc taagaaagaa
    42121 atgagtgagg aggatattaa agcaaatttc atcactcctg ctattgtatc caaaggatgg
    42181 aaaaatggtg agcatatcgc ttacgaagaa tacttcactg atggtcgaat tgaggttaga
    42241 ggagataagg ctcgtcgtaa agaaggaaaa aaatcagact attcactgta ttaccaattt
    42301 ggaactcgaa ttgcaattgt tgaggcaaag gataataaac acagcgttcg agcaggatta
    42361 caacaagcta ttgaatatgg agagatttta gatgttccat ttgtttattc ttcgaatggt
    42421 gatggcttta ttgaacacga ccgtatcacg agagaagaac gtgagctgga gttagacgaa
    42481 ttccctactc gtgaagaatt attttctcgt atgacgaagg aaaaaggatt gacgtacgaa
    42541 attacagaag ctatctcaac tccatactat acagacgcct tctcaatgaa aacgccacgc
    42601 tattatcagc aaatagctat caaccgtact attgaaacag ttgccagagg acaaaaacga
    42661 gtaatgtttg tgatggcaac aggaacgggg aaaacgttca tggcttttca aattattcat
    42721 cgccttcgaa aagctggttt ggctaaacga gttttattct tagcggatag aaacatctta
    42781 gtagaccaaa cgatggctga agactttagg ccattcgaaa aggtaatgac gaaaattaca
    42841 ccaaaacttt tgactgctcc tgaaaaatta aattcttttg aaatttatct agggctttat
    42901 cagcaactaa ctggtgaaga tggaactgaa acacattatc aaaaatttga caaagacttc
    42961 tttgatttaa tcgtaattga tgaagcgcac cgtggttcag ctaaggaaaa cagtaactgg
    43021 cgtaagataa ttgattattt cagttctgcg acacagattg ggatgaccgc tactcctaaa
    43081 gaaaccaaga atgcttccaa tacggaatac tttggtgagc caatctatac ttatagttta
    43141 aaacagggaa tcgaggatgg ttttttggct ccatatcgtg ttatgagagt taatttagat
    43201 gtagatgtgg atggttatcg tccagaaact ggaaaagttg atgctaacgg acaattaata
    43261 gaagataggt actacggcag gaaagatttt gataaaacca ttgtcattga tgatagaacg
    43321 caaagagttg ccaagtttgt ttctgattat atgaagcaaa acaatgcacg atttgataaa
    43381 acaattgttt tttgtgttga tattgaccat gccgagcgaa tgcgtgctgc acttgtaaaa
    43441 gagaatctag acttagtcca agaagactat cgttatgtca tgcaagtaac tggtgacaac
    43501 gctgaaggaa aagctcaact ggataacttt atggatgtca attctaattt tcccgctatt
    43561 gtaacaacgt ctaaattatt aacgacagga gttaatgcta aaacatgtcg tttgattgtt
    43621 ttagactcta atatccaatc catgactgaa tttaaacaaa ttattggtcg tggcacacgt
    43681 ctttatcctc aaaaggggaa agaatttttt acgattattg attttcgaaa tgttaccaat
    43741 ttgtttgctg accctgattt tgatggtgat ccagtgaagg tgctggaaac aggtgcgaaa
    43801 acagtcagtg gttctacgcc cggtttcgta agtgaggaag gtgacccagt agaaaaatat
    43861 atcgttacag acaagcaggt taccattctt aattctactg ttcaagtatt ggatgaaaac
    43921 gggaaactga ttaccgaaag cctgaccgac tacactcgga agaatatctt aggtagctac
    43981 gccactttga acgattttat cacagtttgg catacggcgg ataaaaagaa gcttatctta
    44041 gacgaacttt ataaaaaagg agtttatcta gatgctattc gagagtcgga gggaatatca
    44101 gaacaagaaa tcgatgattt tgatttactc ctaaaacttg cctatggtca aaaagaatta
    44161 accaaaacgg aacgtatcaa taagctcaaa caaagcggat atttatataa atatagtgag
    44221 gaagcgcgtg ctgttttgga aattttactg aacaaataca tggataaagg tattggagaa
    44281 ctcgaaagca ttgaaacatt aaaacttcca gaatttcaga tatatggtgg aaccttcaaa
    44341 atcatcaata cttattttgg agataaaaaa cgatatttac aagcaattaa agaattggag
    44401 caagagctat ttacagtagc ttaatgaaag gaaagtatgt caattacatc atttgtaaaa
    44461 agaattcaag atatcactcg aaacgatgct ggtgttaatg gtgatgctca acgtattgag
    44521 caaatgtctt ggttattatt cttaaaaatt tatgatagcc gtgaaatggt ttgggaatta
    44581 gaagaagacg agtatgagtc aattatccca gaggaattaa aatggcgaaa ttgggctcat
    44641 gctcaaaatg gggaacgggt attgacaggc gatgaattac ttgattttgt caataacaag
    44701 ttattcaaag agttgaaaga gcttgaaata acttcaaata tgcctattcg aaaaacgatt
    44761 gttaaatcag cttttaaaga tgcgaacaac tatatgaaaa atggcgtctt gttacgccaa
    44821 gtcatcaatg ttattgatga agttgatttc aatagccctg aagatcgtca ttcgtttaat
    44881 gatatttacg aaaaaattct taaagatatt caaaatgctg ggaactcagg agaattttat
    44941 acaccacgtg cagcgactga ttttattgcc gaagttcttg acccaaaact tggagaatca
    45001 atggcagacc ttgcttgcgg aacaggaggc ttcttgactt cgactctgaa ccgtttaagt
    45061 agtcaacgta aaactagtga agataccaaa aaatataata cagctgtttt tggtattgaa
    45121 aagaaagcat ttcctcatct tttagcagtt acaaatctgt ttcttcacga aattgatgac
    45181 cctaaaattg ttcatggaaa tactttagag aaaaatgttc gtgaatatac ggatgatgaa
    45241 aaatttgaca ttattatgat gaatccacct tttggagggt cagaattaga aacaataaaa
    45301 aataactttc cagcagaatt acggagttct gaaacagctg atttatttat ggctgtcatt
    45361 atgtatcgtt tgaaagaaaa tggtcgtgtt ggagttattt tacctgatgg ttttctattt
    45421 ggtgaaggtg taaaaactcg cttgaaacaa aaactggtag atgagttcaa cttgcatacg
    45481 attattaggt tgcctcatag tgtctttgca ccgtatacag gaatccatac gaacattctt
    45541 ttctttgata aaacaaagaa aacagaagaa acttggtttt atcgtttaga tatgccagat
    45601 ggttataaaa atttctcgaa aactaagccg atgaagtcag aacacttcaa tcctgttcgt
    45661 gactggtggg aaaatcgtga agagattctg gaaggtaagt tctacaaatc taaatcattt
    45721 acacctagtg aattggctga gttgaattat aatttagacc agtgtggttt tccaaaagag
    45781 gaagaggaaa tcttaaatcc ctttgagttg attcagaatt atcaagcgga aagagcaact
    45841 ttaaatcata agattgataa tgtattagct gatattttgc agttgttgga ggacaaataa
    45901 tgacaccaga acaacttaag gcaagtattc tccaaagagc gatggaaggg aaattagtgc
    45961 cgcaaaatcc caatgacgaa cctgcaagtg aattattaaa gagaattaaa gctgaaaaag
    46021 aaaaacttat cagtgaagga aaaatcaaac gagataaaaa ggaaactgag atatttcgtg
    46081 gtgatgatg
//
LOCUS       DAVKEV010000014        45631 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVKEV010000014 DAVKEV010000000
VERSION     DAVKEV010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45631
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.014"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            632..1084
                     /locus_tag="VWZ68_000766"
     CDS             632..1084
                     /locus_tag="VWZ68_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU9371828.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1103..2440
                     /locus_tag="VWZ68_000767"
     CDS             1103..2440
                     /locus_tag="VWZ68_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU9371829.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2519..3403
                     /locus_tag="VWZ68_000768"
     CDS             2519..3403
                     /locus_tag="VWZ68_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9371830.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3403..4236
                     /locus_tag="VWZ68_000769"
     CDS             3403..4236
                     /locus_tag="VWZ68_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9371831.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4254..6347
                     /gene="nanB"
                     /locus_tag="VWZ68_000770"
     CDS             4254..6347
                     /gene="nanB"
                     /locus_tag="VWZ68_000770"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEU9371832.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWRYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6359..7462
                     /locus_tag="VWZ68_000771"
     CDS             6359..7462
                     /locus_tag="VWZ68_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU9371833.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQLSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7635..8333
                     /locus_tag="VWZ68_000772"
     CDS             7635..8333
                     /locus_tag="VWZ68_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU9371834.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8352..9869
                     /locus_tag="VWZ68_000773"
     CDS             8352..9869
                     /locus_tag="VWZ68_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU9371835.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9994..11322
                     /locus_tag="VWZ68_000774"
     CDS             9994..11322
                     /locus_tag="VWZ68_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9371836.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11574..12440
                     /locus_tag="VWZ68_000775"
     CDS             11574..12440
                     /locus_tag="VWZ68_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9371837.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12456..13295
                     /locus_tag="VWZ68_000776"
     CDS             12456..13295
                     /locus_tag="VWZ68_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9371838.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13567..14019
                     /locus_tag="VWZ68_000777"
     CDS             13567..14019
                     /locus_tag="VWZ68_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU9371839.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYDIDGD
                     KVFLVVQENVLNQAENDQFEYHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14152..14460
                     /locus_tag="VWZ68_000778"
     CDS             14152..14460
                     /locus_tag="VWZ68_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371840.1"
                     /translation="MDGQGITVDEMAWIIRGIVNGLIGRYIKLGTYAAKYGISMARSI
                     LSRAAATAAARVGLSTKISGWILRVAVNVADVYGNFANNIAAAWDAHDKIPNNGRINF
                     "
     gene            14470..14769
                     /locus_tag="VWZ68_000779"
     CDS             14470..14769
                     /locus_tag="VWZ68_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371841.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFDEHTWSTILIASLFGV
                     YDYKPIDKNRKKSKRKKKKEKIDLFMVGTYESFTDKKENSLQRKMMEEQTWHKKE"
     gene            14751..15395
                     /locus_tag="VWZ68_000780"
     CDS             14751..15395
                     /locus_tag="VWZ68_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU9371842.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15564..16481
                     /locus_tag="VWZ68_000781"
     CDS             15564..16481
                     /locus_tag="VWZ68_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEU9371843.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16499..17383
                     /locus_tag="VWZ68_000782"
     CDS             16499..17383
                     /locus_tag="VWZ68_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9371844.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17399..18250)
                     /locus_tag="VWZ68_000783"
     CDS             complement(17399..18250)
                     /locus_tag="VWZ68_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU9371845.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18450..20507
                     /gene="pbp2b"
                     /locus_tag="VWZ68_000784"
     CDS             18450..20507
                     /gene="pbp2b"
                     /locus_tag="VWZ68_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEU9371846.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20518..21114
                     /gene="recR"
                     /locus_tag="VWZ68_000785"
     CDS             20518..21114
                     /gene="recR"
                     /locus_tag="VWZ68_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEU9371847.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21290..22333
                     /locus_tag="VWZ68_000786"
     CDS             21290..22333
                     /locus_tag="VWZ68_000786"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU9371848.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22417..23790
                     /locus_tag="VWZ68_000787"
     CDS             22417..23790
                     /locus_tag="VWZ68_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEU9371849.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELGITDLVERKDSLTFKVNFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     RLENEAK"
     gene            23777..24388
                     /locus_tag="VWZ68_000788"
     CDS             23777..24388
                     /locus_tag="VWZ68_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9371850.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKFLDGQFQEN
                     QEIADLQFFAIDQLPALSEKRITKEQIEILWQVYQGQREQYLD"
     gene            24479..25183
                     /locus_tag="VWZ68_000789"
     CDS             24479..25183
                     /locus_tag="VWZ68_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEU9371851.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25402..26775
                     /gene="ftsA"
                     /locus_tag="VWZ68_000790"
     CDS             25402..26775
                     /gene="ftsA"
                     /locus_tag="VWZ68_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEU9371852.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26792..28051
                     /gene="ftsZ"
                     /locus_tag="VWZ68_000791"
     CDS             26792..28051
                     /gene="ftsZ"
                     /locus_tag="VWZ68_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEU9371853.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARTATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            28056..28727
                     /locus_tag="VWZ68_000792"
     CDS             28056..28727
                     /locus_tag="VWZ68_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEU9371854.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDIIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28737..29276
                     /locus_tag="VWZ68_000793"
     CDS             28737..29276
                     /locus_tag="VWZ68_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEU9371855.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29276..29539
                     /locus_tag="VWZ68_000794"
     CDS             29276..29539
                     /locus_tag="VWZ68_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEU9371856.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29536..30321
                     /locus_tag="VWZ68_000795"
     CDS             29536..30321
                     /locus_tag="VWZ68_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEU9371857.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30330..31118
                     /gene="divIVA"
                     /locus_tag="VWZ68_000796"
     CDS             30330..31118
                     /gene="divIVA"
                     /locus_tag="VWZ68_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEU9371858.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31466..34258
                     /locus_tag="VWZ68_000797"
     CDS             31466..34258
                     /locus_tag="VWZ68_000797"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEU9371859.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGETRKFVVAAELLTSLSEK
                     FGWVDVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEYVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPTQDAVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYANFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            34670..35032
                     /locus_tag="VWZ68_000798"
     CDS             34670..35032
                     /locus_tag="VWZ68_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371860.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNALKIANLVLGIIAIVYYKGDKRVGAAPSVLMIVSGEVSLIPFLGWVGGILA
                     IIGGSLFLATLKKFKSEE"
     gene            35567..36259
                     /locus_tag="VWZ68_000799"
     CDS             35567..36259
                     /locus_tag="VWZ68_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEU9371861.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            36312..38722
                     /locus_tag="VWZ68_000800"
                     /pseudo
     CDS             36312..38722
                     /locus_tag="VWZ68_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
     gene            38972..39673
                     /locus_tag="VWZ68_000801"
     CDS             38972..39673
                     /locus_tag="VWZ68_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9371862.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDVLNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            39675..42383
                     /locus_tag="VWZ68_000802"
     CDS             39675..42383
                     /locus_tag="VWZ68_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU9371863.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQCSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATDQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMSQSAVSSVVQNASAIRLFDSVASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTTKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(42479..42970)
                     /gene="tpx"
                     /locus_tag="VWZ68_000803"
     CDS             complement(42479..42970)
                     /gene="tpx"
                     /locus_tag="VWZ68_000803"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEU9371864.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(43093..44022)
                     /gene="psaA"
                     /locus_tag="VWZ68_000804"
     CDS             complement(43093..44022)
                     /gene="psaA"
                     /locus_tag="VWZ68_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEU9371865.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(44054..44902)
                     /locus_tag="VWZ68_000805"
     CDS             complement(44054..44902)
                     /locus_tag="VWZ68_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU9371866.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(44899..45621)
                     /locus_tag="VWZ68_000806"
     CDS             complement(44899..45621)
                     /locus_tag="VWZ68_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU9371867.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT        13896 a         8132 c        10032 g        13571 t
ORIGIN      
        1 gaaactaaat tccaaattag aaaaagactt gaaatactaa aaaaaaaaaa gtatactcta
       61 attgaaaacg gtaacaaaac taatttagag aatgaaatat agagtatttc tctcttaaaa
      121 gtttttggtg aaacgagatg tagaaaggag atttagccaa agagtctatt agtgctagaa
      181 taatagatta gaattatttt agaaaaacga agtgagcagc ttataaattc aagtccccaa
      241 atagattcat actagtatct tttgcaaaaa ataaagggcg acttccttca tgaatatcaa
      301 tttcatctat aaggaaggta gctaattgaa ctaacttatt tattctgttt gtcgctagaa
      361 aaatcagacc tccttgtgaa gattgaggag atactgaatg aaaatcaaag aagaaactag
      421 caagctagta gcagattgcc caaaacaccg ctttgaggtt gtagataaga ctgacgtata
      481 taatccaagg tgaagcgact gtggtttgaa gagattttca aagagtatag gctagagagt
      541 agtgttttta tgtccttcta gtagaaaatg ctagacagaa gaatggggaa cttggatagg
      601 aaaaatagat tgagaaagga ggttagaaga gatgattatt acaaaaatta gccgtttagg
      661 aacttatgtg ggagtaaatc cacattttgc aacattaata gattttttag aaaaaacagg
      721 actagaaaat ttaacagaag gttcgattgc tatcgatggt aatcgattgt ttgggaattg
      781 ctttacttat ctagcagatg gtcaagcagg ggctttcttt gaaacacacc aaaaatattt
      841 ggatattcat ttagttttgg aaaacgaaga agccatggct gttacatcgc cggaaaatgt
      901 aagcgttacc caagaatatg atgaagagaa agatattgaa ttatacacag ggaaagtgga
      961 acagttggtt catttgagag ctggtgaatg cctcatcact tttccagaag atttacatca
     1021 acccaaggtt cgtataaatg atgaacctgt gaaaaaagtt gtctttaaag ttgcgatttc
     1081 ttaatgtaga aagagaagaa cgatgaaaaa aatgagaaag tttttatgtc tagctggaat
     1141 tgcgctagcg gctgttgcct tggtagcttg ttcaggaaaa aaagaagcta caactagtac
     1201 tgaaccacca acagaattat ctggtgagat tacaatgtgg cactccttta ctcaaggacc
     1261 ccgtttagaa agtattcaaa aatcagcaga tgctttcatg caaaagcatc caaaaacgaa
     1321 aatcaagatt gaaacatttt cttggaatga cttctatact aaatggacta caggtttagc
     1381 aaatggaaat gtgccagata tcagtacagc tcttcctaac caagtaatgg aaatggtcaa
     1441 ctcagatgct ttggttccgc taaatgattc tatcaagcgt attggacaag ataaatttaa
     1501 cgaaactgcc ttaaatgaag caaaaatcgg agatgattac tactctgttc ctctttattc
     1561 acatgcacaa gtcatgtggg ttagaacaga tttgttaaaa gaacataata ttgaggttcc
     1621 taaaacttgg gatcaactct atgaagcttc taaaaaattg aaagaagctg gagtttatgg
     1681 cttgtctgtt ccgtttggaa caaatgactt aatggcaaca cgtttcttga acttctacgt
     1741 acgtagtggt ggaggaagcc tcttaacaaa agatcttaaa gcagacttga caagccaact
     1801 tgctcaagat ggtattaaat actgggttaa attgtataaa gaaatctcac ctcaagattc
     1861 tttgaacttt aatgtccttc aacaagctac cttgttctat caaggaaaaa cagcatttga
     1921 ctttaactct ggcttccata tcggaggaat taatgccaac agtcctcaat tgattgattc
     1981 gattgatgct tatcctattc caaaaatcaa agagtctgat aaagaccaag gaattgaaac
     2041 ctcaaacatt ccaatggttg tttggaaaaa ttcaaaacat ccagaagttg ctaaagcatt
     2101 cttagaagca ctttataatg aagaagacta cgttaaattc cttgattcaa ctccagtagg
     2161 tatgttgcca actattaagg ggattagcga ttctgcagcc tataaagaaa atgaaactcg
     2221 taagaaattt aaacatgctg aagaagtaat tactgaagct gttaaaaaag gtactgctat
     2281 tggttatgaa aatggaccaa gtgtacaagc tggtatgtta actaaccaac acattattga
     2341 acaaatgttc caagatatca ttacaaatgg aacagatcct atgaaagcag caaaagaagc
     2401 agaaaaacaa ttaaacgatt tatttgaggc tgttcagtag atgtaaaaga ctagaaaata
     2461 ggtgggctag tgagctgaaa agctctagcc caatcttgta aaagaaggga gaaggagaat
     2521 ggttaaagaa cgtaatttaa ctcgctggat atttgttttg ccagctatga ttatcgtagg
     2581 attactcttt gtttatccgt ttttctcgag tattttttat agctttacca ataagcattt
     2641 gattatgcct aattataaat ttgttggttt ggctaactat aaagctgtgc tgtcagatcc
     2701 caacttcttt aatgcgttct ttaattcaat taagtggacc gttttctcat tagttggtca
     2761 agttttagta gggtttgtat tggctttagc tcttcacaga gtacgccact tcaagaaatt
     2821 atataggacc ttattgattg ttccttgggc atttcctacc atcgttattg ccttctcttg
     2881 gcagtggatt ctaaacgggg tttatggcta cttacctaat ctaatcgtaa aattaggttt
     2941 aatggaacat acacctgcat ttttgacaga tagtacatgg gcattcctat gtttggtgtt
     3001 tatcaacatt tggtttggag caccaatgat tatggttaat gtgctttcag ctttgcaaac
     3061 agtaccagaa gaacaatttg aggctgctaa gatagatggt gcttcaagtt ggcaggtgtt
     3121 caagtttatc gtctttccac atattaaagt ggttgtagga cttctagttg ttttgagaac
     3181 tgtatggatc tttaataact ttgacattat ctacctcatt actggtggtg gaccagccaa
     3241 tgctacaacg acacttccaa tttttgctta caacctgggt tggggaacta aattgttggg
     3301 tcgtgcttca gcagttacag tattgctctt tatcttcttg gtggcgattt gctttatcta
     3361 ctttgctatc atcagtaagt gggaaaagga gggtagaaaa taatgaagaa gaaatccagt
     3421 atttatttag atattctctc acatgtactt ttagttggtg cgaccatcgt tgcaattttc
     3481 ccattggtat ggattatcat atcttctgtc aaagggaaag gggaattaac tcagtatcca
     3541 acacgatttt ggcctgaaca gtttacatta gattatttca ctcatgttat caacgatttg
     3601 cacttcattg ataacattcg aaacagttta atcattgcct tggctacaac cctcattgcg
     3661 attattattt ctgctatggc agcctatggt attgttcgat tctttcctaa attgggagca
     3721 atcatgtcga gactactcgt cattacctac attttcccac caattttgtt agcaattccc
     3781 tattcaattg ccattgctaa agttgggtta acaaatagtt tatttggctt gatgatggtt
     3841 tatctatctt ttagtgttcc atatgcagtt tggctcttag ttggattttt ccaaacagtt
     3901 ccaattggaa ttgaagaagc ggctagaatt gatggtgcaa ataaatttgt tacgttttat
     3961 aaggttgtgc taccgattgt agcaccaggt attgtagcaa cagctattta tacatttatc
     4021 aatgcttgga atgaattcct gtatgccttg attttaatta acaatacagg aaagatgaca
     4081 gtagcagtag cccttcgttc acttaatggt tcagaaatac tagactgggg agatatgatg
     4141 gcagcgtctg ttattgtagt tcttccatca attattttct tctctatcat ccaaaataag
     4201 attgcaagtg gattatcaga aggatctgtg aagtagacga aagaaggaaa aaaatgaata
     4261 aaagaggtct ttattcaaaa ctaggaattt ctgttgtagg cattagtctt ttaatgggag
     4321 tccccacttt gattcatgcg aatgaattaa actatggtca actgtccata tctcctattt
     4381 ttcaaggagg ttcatatcaa ctgaacaata agagtataga tatcagctct ttgttattag
     4441 ataaattgtc tggagagagt cagacagtag taatgaaatt taaagcagat aaaccaaact
     4501 ctcttcaagc tttgtttggc ctatctaata gtaaagcagg ctttaaaaat aattactttt
     4561 caattttcat gagagattct ggtgagatag gtgtagaaat aagagacgcc caaaagggaa
     4621 taaattattt attttctaga ccagcttcat tatggggaaa gcataaagga caggcagttg
     4681 aaaatacact agtatttgta tctgattcta aagataaaac atacacaatg tatgttaatg
     4741 gaatagaagt gttctctgaa acagttgata catttttgcc aatttcaaat ataaatggta
     4801 tagataaggc aacactagga gctgttaatc gtgaaggtaa ggaacattac ctcgcaaaag
     4861 gaagtattgg tgaaatcagt ctatttaaca aagcaattag tgatcaggaa gtttcaaata
     4921 ttcccttgtc aaatccattt cagttaattt tccaatcagg agattctact caagctaact
     4981 attttagaat accgacacta tatacattaa gtagtggaag agttctatca agtattgatg
     5041 cacgttatgg tgggactcat gattctaaaa gtaagattaa tattgccact tcttatagtg
     5101 atgataatgg gaaaacgtgg agtgagccaa tttttgctat gaagtttaat gactatgagg
     5161 agcagttagt ttactggcca cgagataata aattaaagaa tagtcaaatt agtggaagtg
     5221 cttcattcat agattcatcc attgttgaag ataaaaaatc tgggaaaacg atattactag
     5281 ctgatgttat gcctgcgggt attggaaata ataatgcaaa taaagccgac tcaggtttta
     5341 aagaaataaa tggtcattat tatttaaaac taaagaagaa tggagataac gatttccgtt
     5401 atacagttag agaaaatggt gtcgtttatg atgaaacaac taataaacct acaaattata
     5461 ctataaatga taagtatgaa gttttggagg gaggaaagtc tttaacagtc gaacaatatt
     5521 cggttgattt tgatagtggc tctttaagag aaaggcataa tggaaaacag gttcctatga
     5581 atgttttcta caaagattcg ttatttaaag tgactcctac taattatata gcaatgacaa
     5641 ctagtcagaa tagaggagag agttgggaac aatttaagtt gttgcctccg ttcttaggag
     5701 aaaaacataa tggaacttac ttgtgtcctg gacaaggttt agcattaaaa tcaagtaaca
     5761 gattgatttt tgcaacatat actagtggag aactaaccta tctcatttcg gatgatagtg
     5821 gtcaaacatg gaagaaatcc tcagcttcaa ttccgtttaa aaatgcaaca gcagaagcac
     5881 aaatggttga actgagagat ggtgtgatta gaacattctt tagaaccact acaggtaaga
     5941 tagcttatat gactagtaga gattctggag aaacatggtc gaaagtttcg tatattgatg
     6001 gaattcaaca aacttcatat ggcacacaag tatctgcaat taaatactct caattaattg
     6061 atggaaaaga agcagtcatt ttgagtacac caaattctag aagtggccgt aagggaggcc
     6121 aattagttgt cggtttggtc aataaagaag atgatagtat tgattggaga taccactatg
     6181 atattgattt gccttcgtat ggttatgcct attctgcgat tacagaattg ccaaatcatc
     6241 acataggtgt actgtttgaa aaatatgatt cgtggtcgag aaatgaattg catttaagca
     6301 atgtagttca gtatatagat ttggaaatta atgatttaac aaaataaagg agaaaaacat
     6361 ggttaaatac ggtgttgttg gagcagggta ttttggagct gaattggctc gctacatgca
     6421 aaagaatgat ggagcagaga ttactcttct ctatgatcca gataatgcag aggcgattgc
     6481 agaagaattg ggagcaaaag tagcaagttc cttagatgag ttggtttcta gcgatgaagt
     6541 agattgtgtt atcgtcgcaa ctccaaataa tcttcataag gaaccggtta ttaaggctgc
     6601 acagcatggt aaaaatgttt tctgtgaaaa accaattgcg ctttcttatc aagattgtcg
     6661 cgagatggta gatgcgtgta aagaaaacaa tgtaaccttt atggcaggac atattatgaa
     6721 tttctttaat ggtgttcatc atgcaaaaga actcattaat caaggagtta tcggagacgt
     6781 tctatattgt catacagctc gtaatggttg ggaagaacaa caactgtcag tatcatggaa
     6841 aaaaattcgt gaaaaatcag gtggtcactt gtatcaccac atccatgaat tggattgcgt
     6901 tcaattcctt atggggggca tgcctgaaac tgtaaccatg acaggtggaa atgtggccca
     6961 tgaaggtgaa catttcggtg atgaagatga tatgattttt gtcaatatgg aattttctaa
     7021 taagcgtttt gccttgttag aatggggttc agcttatcgt tggggtgaac attatgtctt
     7081 aatccaagga agcaaaggtg ccatccgctt agacttattc aactgtaaag gaactcttaa
     7141 gctagatggg caagaaagct atttcttgat tcacgaatcg caagaagaag atgatgatcg
     7201 gactcgtatc tatcatagta cagagatgga tggagcaatt gcttatggta aaccaggtaa
     7261 acgtactcca ttatggctat catctgtcat tgataaagaa atgcgctatc tgcatgagat
     7321 tatggaagga gctccagtat cagaagaatt tgcaaaactt ttgacaggtg aagctgccct
     7381 agaagcaatt gctactgcag atgcttgtac ccagtctatg tttgaagatc gcaaagtaaa
     7441 attgtcagaa attgtaaaat aaattttggt attctcctat tataggtcga cttgctcctc
     7501 tgaaagtact tttagaggag ctgtttgact tggctagttt ttgaaactga aatctattat
     7561 actacaaact attgaaagcg ttttaatttt aaggtataat aatctcatag aaataaagaa
     7621 aaggaggaaa gaggatgcca cagattagca aagaagcctt gattgagcaa atcaaagatg
     7681 gaatcatcgt ttcttgtcag gctcttcctc atgaaccgct ttatacagaa gcgggagggg
     7741 tgattccctt gctggtcaaa gcggctgagc aaggtggagc agtcggtatc cgagcaaaca
     7801 gtgttcgcga tatcaaggaa attaaggaag tcactaaact tccaatcatt gggattatca
     7861 aacgtgatta tccacctcag gaacccttca tcacggctac tatgaaagaa gttgatgaat
     7921 tggcagaact ggacatcgag gtgattgctc tggattgtac caagcgtgaa cgctacgatg
     7981 gtttggaaat tcaagagttc attcgtcagg ttaaggagaa atatcctaat cagcttttga
     8041 tggctgatac tagtatcttc gaagaagggc tagcagctgt agaagcagga attgactttg
     8101 tcggaacaac cttatcaggc tacacatcct acagtccaaa agtagacggt ccagattttg
     8161 aattgattaa gaaactctgt gatgccggtg tagatgtcat tgcagaagga aaaattcata
     8221 caccagaaca agccaaacaa atccttgaat atggagtgcg aggcatcgtt gttggtggcg
     8281 ccattactag accaaaagag attacagaac gcttcgttgc tagtcttaaa taagatgtga
     8341 gggggagttt tatgtttaaa gttttacaaa aagttggaaa agcttttatg ttacctatag
     8401 ctatacttcc tgcagcaggt ctacttttgg ggattggtgg tgcactttca aacccaacca
     8461 cgatagcaac ttatccaata ctagacaata gtatttttca atcaatattc caagtaatga
     8521 gctctgcagg agaggttgta ttcagtaatt tgtcactact tctctgtgtg ggattatgta
     8581 ttggcttagc gaaacgagat aaaggaaccg ctgcgttagc aggagtaact ggttacttag
     8641 ttatgactgc aacgatcaaa gctttggtaa aactttttat ggcagaagga tctgcaattg
     8701 atactggagt tattggagca ttagttgtcg gaatagttgc cgtatatttg cacaaccgat
     8761 ataacaatat tcaattacct tccgctttag gattctttgg aggttcacgc ttcgttccta
     8821 ttgttacatc gttctcttct atcttgattg gctttgtctt ctttgttatt tggccacctt
     8881 tccaacaact tcttgtttct acaggtggat atatttctca ggcgggtcca attggaactt
     8941 ttctatatgg atttttaatg agactttctg gagcagtagg cttacatcat ataatttacc
     9001 ctatgttttg gtatactgaa cttggtggtg ttgaaactgt tgcaggacaa acagtggttg
     9061 gagctcaaaa aatatttttt gctcaattag ccgatccggc ccattctgga ttatttacag
     9121 aaggaacaag gttttttgca ggtcgtttct caacaatgat gttcggttta ccggctgcct
     9181 gtttagcgat gtaccatagt gttcctaaaa atcgtcgtaa aaaatacgcg ggtttgtttt
     9241 ttggagttgc tttaacatct tttattaccg gtattacaga accaattgaa tttatgtttc
     9301 tattcgtcag tccggttcta tatgttgttc acgcattcct tgatggtgtt agcttcttta
     9361 ttgcagacgt cttaaatatt tcaataggaa acacattttc aggaggtgta atcgatttca
     9421 ctttatttgg aattttgcag gggaacgcta agacgaattg ggttcttcag attccaattg
     9481 gacttatttg gagtgttttg tattatatta tttttagatg gttcattact caattcaacg
     9541 ttctaacgcc aggacgagga gaagaagtag attctaaaga aatttctgaa tccgcagatt
     9601 caacttcaaa tactgcagat tatttaaaac aggatagcct acaaattatc agagccttgg
     9661 gtggatcaaa taatatagaa gatgtagatg cttgtgtgac acgtttacgt gtagctgtaa
     9721 aagaagttaa tcaagttgat aaagcacttt taaaacaaat tggtgcagtt gatgtcttag
     9781 aagtgaaggg tggcattcaa gcaatctatg gagcaaaagc aatcttatat aaaaatagta
     9841 ttaatgaaat tttaggtgta gatgattaag tacttactga cttaataaaa aacagaggag
     9901 agtgatggat gagtaggatg aaatgaaatc gcatacaaga aataaagaac tcattatcca
     9961 agttggatac gcttattaca taggagaata caaatgaaat ttagaaaatt agcttgtaca
    10021 gtacttgcgg gtgctgcggt tcttggtctt gctgcttgtg gcaattctgg cggaagtaaa
    10081 gatgctgcca aatcaggtgg tgacggtgcc aaaacagaaa tcacttggtg ggcattccca
    10141 gtatttaccc aagaaaaaac tggtgacggt gttggaactt atgaaaaatc aatcatcgaa
    10201 gcgtttgaaa aagcaaaccc agatataaaa gtgaaattgg aaaccatcga cttcaagtca
    10261 ggtcctgaaa aaatcacaac agccatcgaa gcaggaacag ctccagacgt actctttgat
    10321 gcaccaggac gtatcatcca atacggtaaa aacggtaaat tggctgagtt gaatgacctc
    10381 ttcacagatg aatttgttaa agatgtcaac aatgaaaaca tcgtacaagc aagtaaagct
    10441 ggagacaagg cttatatgta tccgattagt tctgccccat tctacatggc aatgaacaag
    10501 aaaatgttag aagatgctgg agtagcaaac cttgtaaaag aaggttggac aactgatgat
    10561 tttgaaaaag tattgaaagc acttaaagac aagggttaca caccaggttc attgttcagt
    10621 tctggtcaag ggggagacca aggaacacgt gcctttatct ctaaccttta tagcggttct
    10681 gtaacagatg aaaaagttag caaatataca actgatgatc ctaaattcgt caaaggtctt
    10741 gaaaaagcaa ctagctggat taaagacaat ttgatcaata atggttcaca atttgacggt
    10801 ggggcagata tccaaaactt tgccaatggt caaacatctt acacaatcct ttgggcacca
    10861 gctcaaaatg gtatccaagc taaactttta gaagcaagta aggtagaagt ggtagaagta
    10921 ccattcccat cagacgaagg taagccagct cttgaatacc ttgtaaacgg gtttgcagta
    10981 ttcaacaata aagacgacaa gaaagtcgct gcatctaaga aattcatcca gtttatcgca
    11041 gatgacaagg agtggggacc taaagacgta gttcgtacag gtgctttccc agtccgtact
    11101 tcatttggaa aactttatga agacaaacgc atggaaacaa tcagcggctg gactcaatac
    11161 tactcaccat actacaacac tattgatgga tttgctgaaa tgagaacact ttggttccca
    11221 atgttgcaat ctgtatcaaa tggtgacgaa aaaccagcag atgctttgaa agccttcact
    11281 gaaaaagcga acgaaacaat caaaaaagct atgaaacaat agtccttagt tattctataa
    11341 aaagtagttt tttaaagaac ctaagagtgt ataccccctt ttccctctac acagatagtg
    11401 taagaaaagg gggcttttgt ttaaaatgta agaaactgtc acgaaattaa aatgaagttc
    11461 ttacataagc gaatcataaa aaatttcatt ttgattttaa aacagttcaa gaaagtcaaa
    11521 aaattattct atttgaaaga gaggtgccga ctgtgaaagt caataaaatc cgtatgcggg
    11581 aaacagtgat ttcctacgct ttcctagcac cagtattatt cttctttgtc atctttgtgt
    11641 tggctccgat ggtgatgggc ttcattacaa gtttctttaa ctactcaatg actaaatttg
    11701 agtttgtagg cttggataac tatatccgta tgtttaaaga tcctgtcttt acaaaatctc
    11761 tgattaacac agttattttg gttattggat ctgtaccagt tgttgttcta ttctcactct
    11821 ttgtagcatc tcagacctat catcaaaatg tcattgccag atccttctac cgtttcgtct
    11881 tcttccttcc tgttgtaacg ggtagtgttg ccgtgacagt tgtttggaaa tggatttatg
    11941 acccactatc agggattcta aactttgtcc ttaagtccag ccacatcatc agccaaaaca
    12001 tttcttggtt gggagataaa aactgggcat tgatggcgat tatgattatt ctcttgacca
    12061 cttcagttgg tcagcccatc atcctttata tcgctgccat ggggaatatt gacaattcac
    12121 tggttgaagc ggcgcgtgtt gatggtgcaa ctgagtttca agttttttgg aagattaaat
    12181 ggccaagcct tcttccaaca actctttata ttgcaatcat cacaacaatt aactcattcc
    12241 agtgttttgc cttgattcag cttttgacat ctggtggtcc aaactactca acaagtacct
    12301 tgatgtacta cctttacgaa aaagccttcc aattgacaga atacggctat gccaacacaa
    12361 ttggtgtctt cttggcagtc atgattgcta tcgtaagctt tgttcaattt aaagtacttg
    12421 gaaacgacgt agaatactaa agaaaggaga cagctatgca atctacagaa aaaaaaccat
    12481 taacagcctt tactgttatt tcaacaatca ttttgctctt gttgactgtg ctgttcatct
    12541 ttccattcta ctggattttg acaggggcat tcaaatcaca acctgataca attgttattc
    12601 ctcctcagtg gttccctaaa atgccaacca tggaaaactt ccaacaactc atggtgcaga
    12661 accctgcctt gcaatggatg tggaactcag tatttatctc attggtaacc atgttcttag
    12721 tttgtgcaac ctcatctcta gcaggttatg tattggctaa aaaacgtttc tatggtcaac
    12781 gcattctatt tgctatcttt atcgctgcta tggcgcttcc aaaacaagtt gtccttgtac
    12841 cattggtacg tatcgtcaac ttcatgggaa tccacgatac tctctgggca gttatcttgc
    12901 ctttgattgg atggccattc ggtgtcttcc tcatgaaaca atttagtgaa aatattccta
    12961 cagagttgct tgaatcagct aaaatcgacg gttgtggtga gattcgtacc ttctggagtg
    13021 tagccttccc gattgtgaaa ccagggtttg cagcccttgc aatctttacc ttcatcaata
    13081 cttggaatga ctacttcatg caattggtaa tgttgacttc acgtaacaat ttgaccatct
    13141 cacttggggt tgcgaccatg caggctgaaa tggcaaccaa ctatggtttg attatggcag
    13201 gagctgccct tgctgctgtt ccaatcgtca cagtcttcct agtcttccaa aaatccttca
    13261 cacagggtat tactatggga gcggtcaaag gataatactc tgagaaaatc tcttcaaact
    13321 acgtcagcgt caccttgcca tacttaagta ttgcctgcgg ttagcttcct agtttgttct
    13381 tcaattttca ttgagtatag gaaaatcaat ctatcaagat acagaagtat attttataga
    13441 tttagagaat atagaggtta taagtgtcta caaaatggag ggtatgcagt tactttatga
    13501 agttttgtca gacacttata aacttaagaa tggttttagt taactatcag aaacgaagga
    13561 aagagtatga tttttgacga tttgaaaaac atcacctttt acaaagggat tcatcctaat
    13621 ttagacaagg ctatcgacta tctctaccaa catcgtaagg attctttcga attaggaaag
    13681 tatgatattg atggagataa agtctttcta gttgttcagg aaaatgtcct caatcaagct
    13741 gaaaatgatc aatttgagta tcataagaac tatgcagatt tgcatttgct ggtagaagga
    13801 catgaatatt cgagctacgg ttcacgtatc aaagacgagg cagtagcatt cgacgaagcg
    13861 agtgacattg gctttgttca ttgtcatgaa cactacccac tcttgttggg ttatcacaat
    13921 tttgcgattt tcttcccagg tgagccacat cagccaaatg gttatgcagg catggaagaa
    13981 aaggttcgga aatatctctt taaaattttg attgattaaa aataggatga attgtttttt
    14041 tgtaaagctt tgacaatact ctaccatgaa attgatcttt gtgaggtagg gaaatgagaa
    14101 taaaatattt aaaaattggt atcttctaag tatgctgcaa gagctagttt cttggatgga
    14161 cagggaatta cagttgatga gatggcttgg ataattaggg gcattgtgaa tggattgatt
    14221 ggtagataca taaaattagg tacttatgca gccaagtatg gtattagtat ggcgcgttcg
    14281 atcttaagta gggcagctgc aactgcagca gcaagagtag gattatcgac caagatttct
    14341 ggatggattt tacgagtagc tgtgaatgta gctgatgtat atggtaattt tgccaacaat
    14401 attgctgcag cttgggatgc acatgataaa attcctaaca atggtcgtat aaacttttaa
    14461 aatgcgagaa tgaaagcact ttgtattttt ttattgaata tgttagcttg gacagtgctt
    14521 gcaatgataa ttcgtggagg gctagatgga tttgatgagc atacttggag tactatttta
    14581 attgcttcgc tgttcggggt atatgattat aagcccatag ataaaaatag aaaaaagtcc
    14641 aaaagaaaaa agaaaaaaga aaaaatagat ttgttcatgg tagggactta tgaaagcttt
    14701 actgacaaaa aagaaaacag tttacaaaga aaaatgatgg aggagcaaac atggcacaaa
    14761 aaggagtaag ccttatcaag gcagcatttg atacagacaa ctttctcatg cgttttagtg
    14821 agaaagtctt ggacatcgtg acagccaatc ttctttttgt cgtctcttgt ttgcccatcg
    14881 tgacgattgg agtggctaaa atcagcctct acgagaccat gttcgaagtt aagaagagca
    14941 gacgggtgcc tgtttttaaa atctatctaa gatctttcaa gcaaaatctg aaactaggtc
    15001 ttcagctggg tttaatggag ttaggaattg tgtttcttac cctttcagat ctctatcttt
    15061 tctggggtca aacagctctg cccttccaat tgctgaaagc catttgttta ggtattctga
    15121 tttttcttac tatcgtgatg ctggctagtt accctatcgc ggcacgttat gacctatctt
    15181 ggaaagaaat tcttcaaaaa ggattgatgt tggctagttt taactttcct tggttcttcc
    15241 tcatgttagc cattcttgtc ctcattgtga tggttcttta tctgtccgcc ttcagtctac
    15301 tcttaggtgg ctcagtcttc ttactttttg ggtttggact attggtcttt atccagactg
    15361 gattgatgga gaaaattttc gcaaaatacc aataggagcc ttatttctga aactactttc
    15421 aaacgctcca aacgctattc tataagcgag aaactaaaat ctaagtgtct ataagatatt
    15481 gaaagccttt tcggtaaagt gtatactaaa gaagtaaaga aaaatctgct ttagcagaaa
    15541 ataaaaataa taggagaaaa tctatgtcag atttgaaaaa atacgaaggt gtcattccag
    15601 ccttctacgc atgttatgat gaacaaggag aagtaagccc agaacgtacg cgtgccttgg
    15661 ttcaatactt cattgataaa ggtgttcaag gtctttatgt caatggttct tctggtgaat
    15721 gtatctacca aagtgttgaa gaccgcaagt taatcttgga agaagtcatg gcggtagcca
    15781 aaggtaaatt gaccatcatt gctcatgttg cctgcaacaa tactaaagat agtatggaac
    15841 ttgctcgcca tgctgaaagc ttgggagtag atgctattgc aacgattcca ccaatttatt
    15901 tccgcttgcc agaatactca gttgccaaat actggaacga tatcagttct gcagctccaa
    15961 acacagacta cgtgatttac aacattcctc aattggcagg ggttgctttg actccaagcc
    16021 tttacacaga aatgttgaaa aatcctcgtg ttatcggtgt taagaactct tctatgccag
    16081 ttcaagatat ccaaaccttt gtcagccttg gtggggaaga ccatatcgtc tttaatggtc
    16141 ctgatgagca gttcctagga ggacgcctca tgggtgctag ggctggtatc ggtggtactt
    16201 atggtgctat gccagaactc ttcttgaaac tcaatcagtt gattgcggat aaggacctag
    16261 aaacagcgcg tgaattgcag tatgctatca acgcaatcat tggtaaactc acttctgctc
    16321 atggaaatat gtacggtgtc attaaagaag tcttgaaaat caatgaaggc ttgaatattg
    16381 gatctgttcg ttcaccattg acaccagtga ctgaagaaga tcgtccagtt gtagaagcgg
    16441 ctgctgcctt gattcgtgaa accaaggagc gcttcctcta atctaaaagg aggtatttat
    16501 gacatactac gttgcaattg atatcggtgg aaccaacatc aagtatggtt tggttgatca
    16561 agaggggcaa cttcttgaat cgcatgaaat gccaactgag gcgcataagg gtggacctca
    16621 tatcttacaa aagaccaaag atatcgtagc tagttattta gaaaaaggcc cagtagcagg
    16681 tgttgccata tcttctgctg ggatggtgga tccggataag ggtgagattt tctatgctgg
    16741 gcctcaaatc cctaactacg caggcaccca gttcaaaaag gaaatcgaag aaagctttac
    16801 tattccttgt gagattgaaa atgatgtcaa ctgtgcaggt cttgctgagg cagtatctgg
    16861 ttcaggcaag ggagcaagtg tgacactttg cttgaccatt ggaaccggta tcggtggttg
    16921 cttgattatg gataggaaag tcttccatgg ttttagcaat tcagcctgtg aagtcgggta
    16981 tatgcatatg caggatggag cttttcagga tctcgcttct acaacagctt tagtgaaata
    17041 tgtagctgaa gcccatggag aagatgttga tcagtggaat ggccgacgta tctttaagga
    17101 agctactgaa ggaaacaaaa tctgcatgga aggtattgac cgtatggttg actatctagg
    17161 aaaaggtctg gcaaatattt gttatgtggc caatccagaa gtggttattc ttggtggtgg
    17221 tatcatgggg caagaggcta tcctcaaacc taagatccgc acagccttga aagaggcatt
    17281 ggtaccaagt ttagcagaaa aaacacgatt agaatttgcc catcaccaaa atacagcagg
    17341 gatgttgggt gcatattatc attttaagac aaaacaatcc tagtttggct cagccaaact
    17401 aggattttct tacacgtttt tgtctacgat agccgttgag ttttttattt tcccagtagc
    17461 tattaaagat tttttccttg ctttcgcgat tgatttccaa aaagtaggca taaatcaaat
    17521 cgataaagaa gagcatagga agttgagcgg atattcgttg gatgtaggag ggttggctgt
    17581 gggtggctac aagaacagtc tctgtatagg tctggctatc tttattggga acacttgtaa
    17641 agagtacagt ctttgccccc atctccttgg catctaatag actatctaaa atagaaggag
    17701 ttgagcctga aagtgagaaa cccagtacta gacaattttc atccatgatg ctggttgtcc
    17761 aggcaaagcc gtcttggtct gtcaaagctt cgcagaccac acctagtcgc ataaaacgta
    17821 atttcatttc acgggcgacg aggccagaac tccctgttcc aaagaagtag atacgctcag
    17881 catcttcgat tagctgggca attcgctcta gttggatttc gtcaatcaag tcttgtgttt
    17941 gttccctcat attgctataa cttctgagga ctcgtttggt cagtggacta tgcttggaga
    18001 cttggttggc ttgattttct gcctgatgtt ggtattggaa aataaattct cggtagccag
    18061 taaagccaca ctttttagca aagcgggtca aagcagcttg agaaatatgt aatttttggg
    18121 tgacttgttg agaagataaa tcatctgtaa tcgtttcagc ttgcaaaaaa tagcgagcga
    18181 tttcttgctc taggtctgtc atttcttcaa aatgtgaatc aatgatagtt gcgatatctg
    18241 gtttgtccat agggaaagct cctttacatg ggtcatactg gaagactaga tcagggaata
    18301 gtcacacttc attataacac ataatataag gatagataaa taaaaacgca tctctgtttt
    18361 aaaaacgaaa aaatcgaaaa agcttctctc ttttccataa ttttctactc aaattgtggt
    18421 acaattaaga gtaagatttt aagttagaaa tgagactgat ttgtatgaga aaatttaaca
    18481 gccattcgat tccgattcgg cttaatttat tgttttcaat cgtcatttta ctctttatga
    18541 ccattattgg tcgtttgttg tatatgcagg ttttgaacaa ggatttttac gaaaaaaagc
    18601 tagcctcagc tagtcagacc aagattacaa gcagttcagc ccgtggggaa atttatgatg
    18661 ctagtggaaa acctttggta gaaaatacgt taaagcaggt tgtttccttt acgcgtagca
    18721 ataaaatgac ggctacagac ttaaaagaaa cagctaaaaa gttactgact tatgtgagca
    18781 tcagttctcc aaatttgaca gaacgccagc tggcggatta ctatttggct gatcctgaaa
    18841 tctataaaaa aacagtggaa gctctcccaa gtgagaaacg cttggattca gatggcaatc
    18901 gtctatccga atcagaactg tataacaatg cggtcgatag tgtccaaaca agtcaactaa
    18961 actatacaga ggatgaaaag aaagaaatct atctttttag tcagttaaat gctgttggaa
    19021 actttgcgac aggaaccatt gctacagatc ctctaaatga ttctcaggtg gctgttattg
    19081 cctctatttc aaaggagatg cctggcatta gtatttctac ttcttgggat agaaaggttt
    19141 tggaaacttc cctttcttct atagttggga gtgtatccag tgaaaaagct ggtctcccag
    19201 cggaagaagc agaagcctat cttaaaaaag gctattctct aaatgatcgt gtaggaacct
    19261 cctatttgga aaagcaatat gaagagacct tacaaggaaa acgctcggta aaagaaatcc
    19321 atctggataa atatggcaat atggaaagcg tggatacaat tgaggaaggt agtaagggaa
    19381 acaatatcaa actgaccatt gatttggctt tccaagatag cgtggatgct ttactgaaaa
    19441 gttatttcaa ttccgagcta gaaaatggtg gagccaagta ttctgaaggt gtctatgcag
    19501 tcgcccttaa cccaaaaaca ggtgcggttt tgtctatgtc agggattaaa catgacttga
    19561 aaacgggaga gttgacgcct gattccttgg gaacggtaac caatgtcttt gttccaggtt
    19621 cggttgtcaa ggcggcgacc atcagctcag gttgggaaaa tggagtcttg tcaggaaacc
    19681 agaccttgac agaccagtcc attgtcttcc aaggttcagc tcccatcaat tcttggtata
    19741 ctcaggctta cggttcattc cctatcacag cggtccaagc tctggagtat tcatcaaata
    19801 cctatatggt ccaaacagcc ttaggtctta tggggcaaac ctatcaaccc aatatgtttg
    19861 tcggcaccag caatctagag tctgctatgg agaaactgcg ttcaaccttt ggcgaatatg
    19921 gcttgggtac tgcgacagga attgacctac cagatgaatc tactggattt gttcccaaag
    19981 agtatagctt tgctaattac attactaatg cctttgggca gtttgataac tatacgccga
    20041 tgcagttggc tcagtatgta gcaactattg caaataatgg tgttcgtgtg gctcctcgta
    20101 ttgttgaagg catttatggt aataatgata agggaggact gggtgacttg attcagcaac
    20161 tgcaaccgac agagatgaat aaggtcaata tatccgactc cgatatgagc atcttgcacc
    20221 aaggttttta tcaggttgcc catggtacta gtggattgac aactggacgt gccttttcaa
    20281 atggcgcctt ggtatccatt agcggaaaaa caggtacagc cgaaagctat gtggcagatg
    20341 gtcagcaagc aaccaatacc aatgcggtgg cctatgcccc atctgataat ccccaaatcg
    20401 ctgttgcagt ggtctttcct cataatacca atctaacaaa tggtgtagga ccttccattg
    20461 cgcgtgacat tatcaatctg tatcaaaaat accatccaat gaactagaaa ggaaattatg
    20521 ctttatccaa cacctattgc caagttgatt gacagttatt ctaagttacc aggtatcggg
    20581 attaagacgg ctacgcgtct ggccttttat acgattggga tgtctgctga tgatgtcaat
    20641 gaatttgcaa aaaatctcct ttctgctaag agagaattga catattgttc tatttgtgga
    20701 cgtttgacag acgacgatcc ttgttctatc tgtactgatc cgactcgtga ccagacaaca
    20761 attttagttc ttgaggatag tagagatgtg gcagccatgg aaaatatcca agaataccat
    20821 ggactctatc atgtccttca tggcctcatt tctcctatga atggtatcag tccggacgat
    20881 atcaatctca agagccttat gactcgtctt atggatagtg aagtttcaga agtgattgtg
    20941 gcgactaatg ctacagcgga tggtgaagcg acttccatgt atctttcacg tttgctcaag
    21001 ccggctggta tcaaggttac gcgtctagca cgaggtctcg ctgtgggagc ggacattgag
    21061 tatgcggacg aagtgacact cttacgagcg attgaaaatc ggacagagtt gtaagtgtag
    21121 gcaaatttac gaactccatt catttataaa aaatcaaaga ggctgaaaat cgttcctatc
    21181 ggcctctttt tgtatagtgt gatgagtagg atcaggttca agttttaaaa aaccaagcaa
    21241 atatgatata ctaaagagcg agtattctag tagaattagg acaaataata tgaaacaaac
    21301 gattattctt ttatatggtg gacggagtgc ggaacgcgaa gtctctgtcc tttcagctga
    21361 gagtgtcatg cgtgcggtca attacgaccg tttcacagtc aagactttct ttatcagtca
    21421 gtcaggtgac tttatcaaaa cacaggaatt tagtcatgct ccggggcaag aagaccgtct
    21481 catgaccaat gaaaccattg attgggataa gaaagttgca ccaagtgcta tctacgaaga
    21541 aggtgcagtg gtctttccag tccttcacgg gccaatggga gaagatggct ctgttcaagg
    21601 attcttggaa gttttgaaaa tgccttacgt tggttgcaac attttgtcat caagtcttgc
    21661 catggataaa atcacgacta agcgtgttct ggaatctgct ggtattgccc aagttcctta
    21721 tgtggctatc gttgaaggcg atgatgtgac tgctaaaatc gctgaagtgg aagaaaaatt
    21781 ggcttatcca gtcttcacta agccgtcaaa catggggtct agtgtcggta tttctaagtc
    21841 tgaaaaccaa gaagaactcc gtcaagcctt aaaacttgcc ttccgatatg acagccgtgt
    21901 cttggttgag caaggagtga atgcccgtga aattgaggtt ggcctcttgg gtaactacga
    21961 tgtcaagagc acgctacctg gagaagttgt caaggacgtt gccttttatg actacgatgc
    22021 caagtatatt gataacaaga ttactatgga tattcctgcc aaaatcagtg atgatgtggt
    22081 ggctgtcatg cgtcaaaatg cagaaacagc cttccgtgcc attggtggcc ttggtctatc
    22141 tcgttgcgat ttcttctata cagataaggg agagattttt ctcaacgagc tcaataccat
    22201 gccaggtttt acccagtggt ctatgtaccc actactttgg gacaatatgg ggatcagcta
    22261 cccagaacta atcgagcgtt tggttgacct tgccaaggaa agttttgaca agcgcgaagc
    22321 gcatttgata taaaatgaaa gagagggtag aagccagaac catcactgca cggtgactag
    22381 agttctcgga cttcagccct ttttaaagga gtagaaatga aattaacaat ccatgaaatt
    22441 gcccaagttg ttggagccaa aaatgatatc agtatctttg aggacaccca gttagaaaaa
    22501 gctgagtttg atagtcgttt gattggaact ggagatttat ttgtgccact taaaggtgcg
    22561 cgtgatggcc atgactttat tgaaacagcc tttgaaaatg gtgcagcagt aaccttgtct
    22621 gagaaagagg tctcaaatca tccttacatt ctagtagatg atgttttgac agcctttcaa
    22681 tccctagcat cctactatct tgaaaaaacg actgttgatg tctttgctgt tacaggttca
    22741 aatggcaaga caacgactaa ggatatgttg gcgcatttac tgtcaacaag atacaagacc
    22801 tacaaaacac aaggcaatta caataatgag attggccttc cttacacagt tcttcatatg
    22861 cctgaaggaa cagaaaagtt ggttttggag atgggacagg atcacttggg agatattcat
    22921 ctcttgtctg aattggctcg tccaaaaaca gccatcgtga ccttggttgg agaagctcat
    22981 ttggcctttt tcaaagatcg ttctgagatt gctaaaggaa aaatgcaaat tgcagacgga
    23041 atggcttcag gttccttgct tttagcgccg gctgacccta tcgtagagga ctatttgcca
    23101 actgataaaa aggtggttcg ttttggtcaa ggagcagagc tgggaattac cgacttggtt
    23161 gagcgcaaag atagtctgac cttcaaggtc aatttcttag agcaagccct tgatttgcca
    23221 gtaactggca agtacaatgc gacaaatgct atgattgcat cctatgttgc cttgcaagaa
    23281 ggagtttcag aggagcaaat tcgtttggcc ttccaacatc ttgaattgac gcgtaaccgt
    23341 accgagtgga agaaagcagc caatggagca gatatcctgt cagatgttta taatgccaat
    23401 ccaactgcta tgaaactgat tttagagact ttctctgcca ttccagccaa tgaaggtggc
    23461 aagaaaattg cagtgttggc ggatatgaag gagcttggtg accagtctgt tcaacttcat
    23521 aatcagatga ttttgagcct ctccccagat gtgcttgata tcgttatttt ctatggagaa
    23581 gatattgctc agttggctca attggccagt caaatgtttc caatcggcca cgtttactac
    23641 ttcaagaaaa cagaagacca ggatcaattt gaagacctag tcaagcaggt taaggaaagc
    23701 cttggagcct atgaccaaat cttgctaaaa ggttctaact ctatgaatct agccaaattg
    23761 gtagaacgtt tagaaaatga agccaagtga ttttgtcaag tatctgcaaa gaatgattgc
    23821 ccttacagat actggcttaa cctttacaaa agatcctttt gaccgtgagc gctacgagga
    23881 cttgcgaagt ctgttatctg aaatgttgaa tcagggatca gacctggatg cagaagaagt
    23941 agcagaagtc ttgaaaccaa cttcagctta tgcgactccc ttaatggacg tccgtgcttg
    24001 gattgttgag gatgagaaga tttgtctggt taggggacaa ggagaggata gttgggcttt
    24061 gccaggtggc tttggtgaag tcggctattc tccaactgaa aatattctca aggaaattga
    24121 agaagaaacc ggttttaaag ccaaagttga aagactgcta gctgtttttg ataccaatcg
    24181 tttccaacta cagagtaaac aatatgcaaa gtttgttttt gaatgtaagt ttctcgatgg
    24241 acaattccaa gaaaatcaag aaattgcaga ccttcaattt tttgccattg atcaactgcc
    24301 agccttatct gaaaaacgca ttaccaagga gcaaatcgag attctttggc aggtttatca
    24361 aggtcagagg gagcaatatc ttgactaaga agatgattat cgtattttta aatccatttt
    24421 taacaactag catggtataa taatatgcag gaaaattttg aattatgagg aagactagat
    24481 gaatttatgg gatattttct ttacgactca ggcaaccgag ccgcccaaat ttgacctttt
    24541 ttggtatgtt agcctattta cgctcttagc cttaaccttt tatacagccc atcgctatcg
    24601 tgaaaagaag gtttaccaac gatttttcca aatcttgcag actgttcagt taatccttct
    24661 ttatggttgg tactgggtca atcatatgcc actgtcagaa agcctaccct tttaccattg
    24721 ccgtatggct atgtttgtgg tactcttgct tcctggtcag tccaaatata aacaatactt
    24781 tgcattattg ggaacatttg ggacattagc agcctttgtt tatccagtgc cagatgctta
    24841 cccttttcca catatcacca ttctatcctt tatctttggt catttagcac tcttggggaa
    24901 ctctctagtt tatctattga gacagtataa tgcgcgattg ctggatgtga agggaatttt
    24961 tctcatgacc tttgccctaa atgccttgat ttttgtggtc aatttggtga caggtggcga
    25021 ttacggattt ttgacaaaac cgccattggt tggggatcac ggtctagtag ctaattattt
    25081 acttgtttca attgtgctgg tagctactat cagtttgact aagaaaatct tagaattctt
    25141 tttagctcaa gaagcagaaa aaatgattgc aaaggaagct taacacagag ctttcttttt
    25201 tgctcttaga gagtttttac aagcagctta taaaataaga atttctgaat agacaaactc
    25261 aaaaaatggc tgggaaattt aggaaaaaag caagcacgat taaatttttt gtgttataat
    25321 attttgtgaa tagctatgcc tatgtttagc tatggaataa tacgaagtgc gaaacttgga
    25381 agatagagag gaagcgatgt aatggctaga gaaggctttt ttacaggtct agatattgga
    25441 acaagctctg tcaaggtgct tgtggccgag cagagaaatg gtgaattaaa tgtaattggc
    25501 gtgagtaatg ccaaaagtaa aggtgtaaag gatggaatta ttgttgatat tgatgcagca
    25561 gcaactgcta tcaagtcagc catttcccaa gcggaagaaa aggcaggcat ttcgattaaa
    25621 tcagtgaatg tcggcttgcc tggtaatctt ttgcaggtag aaccaactca ggggatgatt
    25681 ccagtaacat ctgatactaa ggaaattacg gatcaagatg ttgaaaatgt tgtcaaatca
    25741 gctttgacaa agagtatgac acctgaccgt gaagtcatta cctttattcc tgaagaattt
    25801 attgtggatg gtttccaagg gattcgtgac ccacgtggta tgatgggggt tcgccttgaa
    25861 atgcgtggtt tgctttatac aggacctcgt actatcttgc acaatttgcg taagacggtt
    25921 gagcgtgcag gtgttcaggt tgaaaatgtt atcatttcac cactagcaat ggttcagtct
    25981 gttttgaacg aaggggaacg tgaatttggt gctacagtga ttgatatggg ggcaggtcaa
    26041 acgactgtcg ctacaatccg taatcaagaa ctccagttca cacatattct ccaagaaggt
    26101 ggagattatg taactaaaga tatctccaag gttttgaaaa cctctcgcaa attagcggaa
    26161 ggcttgaaac tgaattacgg ggaagcctat ccgcctcttg caagcaaaga aaccttccaa
    26221 gtagaggtta ttggagaagt ggaagcagtc gaagtgacgg aagcctactt gtcagaaatt
    26281 atttctgcac gaatcaagca catccttgaa caaatcaagc aagaattaga tagaaggcgt
    26341 ctattggacc tccctggtgg tattgtctta atcggtggga atgccatttt accaggtatg
    26401 gttgagcttg ctcaggaagt ctttggcgtc cgtgtcaagc tttatgttcc aaatcaagtt
    26461 ggtatccgta atccagcctt tgcgcatgtg attagtttat cagaatttgc gggtcaatta
    26521 acagaagtta atcttttggc tcagggagcg ataaaaggtg agaatgactt aagtcatcag
    26581 ccaattagtt ttggtgggat gctgcaaaaa acagctcagt ttgtacaatc aacgcctgtt
    26641 caaccagctc ctgctccaga agtagagccg gtggcgccta cagaaccaat ggcggatttc
    26701 caacaagctt cacaaaataa accgaaatta gcagatcgtt tccgtggctt gatcggaagc
    26761 atgtttgacg aataaagagg aaaaataaat tatgacattt tcatttgata cagctgctgc
    26821 tcaaggggca gtgattaaag taattggtgt cggtggaggt ggtggcaatg ccatcaaccg
    26881 tatggtcgac gaaggtgtta caggcgtaga atttatcgca gcaaacacag atgtacaagc
    26941 attgagtagt acaaaagctg agactgttat tcagttggga cctaaattga ctcgtggttt
    27001 gggtgcagga ggtcaacctg aggttggtcg taaagccgct gaagaaagcg aagaaacact
    27061 gacggaagct attagtggtg ccgatatggt cttcatcact gctggtatgg gaggaggctc
    27121 tggaactgga gctgctcctg ttattgctcg tatcgccaaa gatttaggtg cgcttacagt
    27181 tggtgttgta acacgtccct ttggttttga aggaagtaag cgtggacaat ttgctgtaga
    27241 aggaatcaat caacttcgtg agcatgtaga cactctattg attatctcaa acaacaattt
    27301 gcttgaaatt gttgataaga aaacaccgct tttggaggct cttagcgaag cggataacgt
    27361 tcttcgtcaa ggtgttcaag ggattaccga tttgattacc aatccaggat tgattaacct
    27421 tgactttgcc gatgtgaaaa cggtaatggc aaacaaaggg aatgctctta tgggtattgg
    27481 tatcggtagt ggagaagaac gtgtggtaga agcggcacgt aaggcaatct attcaccact
    27541 tcttgaaaca actattgacg gtgctgagga tgttatcgtc aacgttactg gtggtcttga
    27601 cttaaccttg attgaggcag aagaggcttc acaaattgtg aaccaggcag caggtcaagg
    27661 agtgaacatc tggctcggta cttcaattga tgaaagtatg cgtgatgaaa ttcgtgtaac
    27721 agttgtcgca acgggtgttc gtcaagaccg cgtagaaaag gttgtggctc cacaagctag
    27781 aactgctact aactaccgtg agacagtgaa accagctcat tcacatggct ttgatcgtca
    27841 ttttgatatg gcagaaacag ttgaattgcc aaaacaaaat ccacgtcgtt tggaaccaac
    27901 tcaggcatct gcttttggtg attgggatct tcgccgtgaa tcgattgttc gtacaacaga
    27961 ttcagtcgtt tctccagtcg agcgctttga agccccaatt tcacaagatg aagatgaatt
    28021 ggatacacct ccatttttca aaaatcgtta agtaaatgaa tgtaaaagaa aatacagaac
    28081 ttgtttttcg agaagttgca gaggctagtc tgagtgctca tcgagagagt ggttcggtct
    28141 ctgtcattgc agttaccaag tatgtagatg taccgacagc ggaagccttg cttccgctag
    28201 gtgttcatca tatcggtgaa aatcgtgtag ataagtttct ggaaaaatat gaagctttaa
    28261 aagatcgaga tgtgacttgg catttgattg gtaccttgca aagacgtaag gtgaaagata
    28321 tcattcaata cgttgattat ttccatgcat tggactcagt aaagctagca ggggaaattc
    28381 aaaaaagaag tgaccgagtc atcaagtgtt tccttcaagt aaatatttct aaagaagaaa
    28441 gcaaacacgg tttttcgaga gaggaactgc tggaaatctt gccagagtta gccagactag
    28501 ataagattga atatgttggt ttaatgacga tggcaccttt tgaggctagc agtgagcagt
    28561 tgaaagagat tttcaaggcg acccaagatt tacaaagaga aattcaagag aaacaaattc
    28621 caaatatgcc tatgaccgag ttaagtatgg gaatgagtcg tgattataaa gaagcgattc
    28681 aattcggttc cacttttgtt cgtataggta catcattttt taagtaggag agaaccatgt
    28741 ctttaaaaga tagattcgat agatttatag attattttac ggaggatgag gattcaagtc
    28801 tcccttatga aaaaagagat gagcctgtgt ttactccagt aaattcttca caggaaccgg
    28861 ctctcccaat gaatcaacct tcacagtcgg ctggtacaaa agagaacaat atcaccagac
    28921 ttcatgcaag acaacaggaa ttggcaaatc agagtcagcg tgcaacggat aaggtcatta
    28981 tagatgttcg ttatcctaga aaatatgagg atgcaacaga aattgttgat ttattggcag
    29041 gaaacgaaag tatcttgatt gattttcagt atatgacaga ggtgcaggct cgtcgttgtt
    29101 tggactattt ggatggagct tgtcatgttt tagctggaaa tttgaaaaag gtagcttcta
    29161 ccatgtattt gttgacacca gtgaatgtta ttgtaaatgt tgaagatatc cgtttaccag
    29221 atgaagatca acagggtgag ttcggttttg atatgaagcg aaatagagta cgataatgat
    29281 ttttttaatt cgtatgattt ataatgcagt ggatatttac tccctgattt tggtagcctt
    29341 cgctgtcatg tcttggtttc caggtgccta cgaatccagt ttaggtcgtt ggattgtagc
    29401 gttggtgaaa ccagtgcttg ctcccttgca acgcctgcct ttacagatag cgggtcttga
    29461 tttatctgtt tgggtcgcga ttgttttggt tcgattttta ggagaaaacc tagtgcgttt
    29521 tctggcgatg ataggatgaa taaagggatt tatcagcatt tctccataga agatcgtcca
    29581 tttcttgaca agggaatgga atggataaag aaggtagaag atagctatgc tcctttttta
    29641 actcctttta tcaatcctca tcaggagaag ctattaaaga ttttggccaa aacctatggt
    29701 cttgcttgta gcagtagtgg ggaattcgtc tcgagtgagt atgttcgagt tttattatac
    29761 ccagattatt tccaaccaga gttttcagat tttgaaatat ctctccagga aattgtgtat
    29821 tccaataaat ttgaacattt aacgcatgct aagattttag ggacagtcat caatcaatta
    29881 gggattgaac ggaaactttt tggagatatc ctagtagatg aagaacgggc gcagattatg
    29941 attaatcagc agtttcttct tctctttcaa gatggactaa agaaaattgg tcgtatacct
    30001 gtttcgctgg aggaacgtcc tttcaccgag aaaatagata agctagaaca gtatcgagaa
    30061 ctggatttat ctgtgtctag ttttcgatta gatgttcttt tatcaaatgt tttgaaacta
    30121 tctaggaatc aagcaaacca gttgattgaa aagaaacttg tccaagtaaa ttatcatgtg
    30181 gtagacaaat cagattacac tgttcaagtt ggagacttga ttagtgtgag aaaatttggt
    30241 cgcttgagat tacttcaaga taagggacaa acgaaaaaag agaagaaaaa aataaccgtc
    30301 cagttattat taagtaagtg aggaatagaa tgccaattac atcattagaa ataaaggaca
    30361 agacttttgg aactcgattc agaggttttg atccagaaga agtcgatgaa tttttagata
    30421 ttgtggttcg tgattacgaa gatcttgtgc gtgcgaatca tgataaaaat ttgcgtatta
    30481 agagtttaga agagcgtttg tcttactttg atgaaataaa agattcattg agccagtctg
    30541 tattgattgc tcaggataca gctgagagag tgaaacaggc ggcgcatgaa cgttcaaaca
    30601 atatcattca tcaagcagag caagatgcgc aacgcttgtt ggaagaagct aaatataagg
    30661 caaacgagat tcttcgtcaa gcaactgata atgctaagaa agtcgctgtt gaaacagaag
    30721 aattgaagaa caagagccgt gtcttccacc aacgtctcaa atctacaatt gagagtcagt
    30781 tggctattgt tgaatcttca gattgggaag atattctccg tccaacagct acttatcttc
    30841 aaaccagtga tgaagccttt aaagaagtgg ttagcgaagt acttggagaa ccgattccag
    30901 ctccaattga agaagaacca attgatatga cacgtcagtt ctctcaagca gaaatggaag
    30961 aattacaagc tcgtattgag gtagccgata aagaattgtc tgaatttgaa gctcagatta
    31021 aacaggaagt ggaaactcca actcctgtag tgagtcctca agttgaagaa gagcctctgc
    31081 tcatccagtt ggcccaatgt atgaagaacc agaagtagct ccagtgcatc cgacaggtcc
    31141 aacaccagct acagaaactg ttgattcagc accaggattt gaagcaccgc aagaatccgt
    31201 tacaatttta taagaaacga tgtgagaaca atatcttatc cttatatttc cagcgagcag
    31261 gagatggtgt gagtcctgca ttccctaacg ataagattat cctctcaaaa actcaagtct
    31321 gaatctagta agatttgacg tttcccacgt tacgggataa gagggagaaa gactaaatct
    31381 ttttccgaat aaaggtggta ccacgatttt cgtccttttt ggaagtcgtg gtttttaatt
    31441 tgttattatt tataaaggag ataccatgaa actaaaagat acccttaatc ttgggaaaac
    31501 agctttccca atgcgtgcag gccttccgac caaagagcca gtttggcaaa aggaatggga
    31561 agatgcaaaa ctttaccaac gtcgtcaaga actaaatgaa gggaaaccgc attttgtctt
    31621 gcatgatggc cctccatacg caaacggaaa tatccacgtt ggacatgcca tgaatcatat
    31681 ctcaaaagat atcatcattc gttctaagtc tatgtcaggt tttaacgcac cttatatccc
    31741 aggttgggat actcatggtc tgccaatcga gcaagttttg gcaaagcaag gtgtgaagcg
    31801 caaagaaatg gacttggttg agtacttgaa actttgccgt gaatacgctc tttctcaagt
    31861 ttataaacaa cgtgatgatt tcaagcgctt ggggatgtca ggtgactggg aaaatttata
    31921 tgtgacttta actccagact acgaagcagc ccaaatccgt gtatttggtg agatggctaa
    31981 taagggttat atctaccgtg gtgctaagcc agtttactgg tcttggtcat ctgagtcagc
    32041 ccttgccgaa gcggaaattg aataccatga tttggtttca acttcccttt actatgccaa
    32101 taaggtaaaa gatggcaaag gtgttctaga tacagatact tatatcgttg tttggacaac
    32161 tactccattt actatcacag cttctcgtgg tttgactgtt ggtgcagata ttgattacgt
    32221 tttggttcaa cctgctggtg aaactcgtaa gtttgtcgtt gctgcagaat tgttgactag
    32281 cttgtctgag aaatttggct gggttgatgt tcaagttttg gcaacttacc gtggtcaaga
    32341 actcaaccac atcgtaacag aacatccatg ggatacagct gtagatgaat tggttatcct
    32401 tggtgaccac gttacaactg actctggtac aggtattgtc catacagccc ctggttttgg
    32461 tgaggacgat tacaatgttg gtattgctaa taatcttgaa gtcgcagtga ctgttgatga
    32521 acgtggtatc atgatgaaga atgctggtcc tgaatttgaa ggtcaattct atgaaaaggt
    32581 agttccaact gttattgaaa aacttggtaa cctccttctt gcccaagaag aaatctctca
    32641 ctcatatcca tttgactggc gtaccaagaa accaattatc tggcgtgcag taccacagtg
    32701 gttcgcctct gtttcaaaat tccgccaaga aatcttggat gctattgata aagttaaatt
    32761 ccatacagaa tggggtaaag tacgtctata taatatgatt cgtgaccgtg gtgactgggt
    32821 tatctctcgt caacgtgctt ggggtgttcc acttccaatc ttctatgcag aagacggtac
    32881 agctatcatg acagctgaga ctatcgaata tgtggctcaa ctctttgaag tacatggttc
    32941 aagcatttgg tgggaacgtg atgccaaaga cctcttgcca gaaggattta cacatccagg
    33001 ttctccaaat ggcgagttca aaaaagaaac tgatatcatg gacgtttggt ttgactcagg
    33061 ttcatcatgg aatggtgttt tggtaaatcg tccaaatctg acttatccag ctgaccttta
    33121 ccttgaaggt tctgaccaat accgtggttg gttcaactca tcactcatta catctgttgc
    33181 caaccatggc gtagcacctt acaaacaaat cttgtcacaa ggttttaccc ttgacggtaa
    33241 aggtgagaag atgtctaaat ctcttggaaa taccattgct ccaagcgatg ttgaaaaaca
    33301 atttggtgct gaaatcttgc gtctctgggt aacaagtgtt gactcaagca atgacgtgcg
    33361 tatctctatg gatatcttga gccaagtctc tgaaacttac cgtaagattc gtaatactct
    33421 tcgtttcttg attgccaata catctgactt taacccaact caagatgcag tcgcttacga
    33481 tgaacttcgt tcagttgata agtacatgac cattcgcttt aaccagcttg tcaagaccat
    33541 tcgtgatgcc tatgcaaact ttgaattctt gacaatctac aaggccttgg tgaactttat
    33601 caacgttgat ttatcagcct tttaccttga ttttgctaaa gatgttgttt acatcgaagg
    33661 tgctaaatca ctggaacgtc gtcaaatgca gactgtcttc tatgatattc ttgtcaaaat
    33721 caccaaactc ttgacaccaa tccttcctca cactgcggaa gaaatctggt catatcttga
    33781 gtttgaaaca gaagacttcg tccaattgtc agaattacca gaagttcaaa cttttgctaa
    33841 ccaagaagaa atcttggata catgggcagc cttcatggac tttcgtggac aagcacaaaa
    33901 agccttggaa gaagctcgta atgcaaaagt tatcggtaaa tcacttgaag cacacttgac
    33961 agtttatcca aatgaagtgg tgaaaactct actcgaagca gtaaatagca atgtggctca
    34021 acttttgatc gtgtctgagt tgaccatcgc agaaggacca gctccggaag ctgcccttag
    34081 cttcgaagat gtagccttca cagttgaacg tgctgctggt gaagtatgtg accgttgccg
    34141 tcgtattgac ccaacaacag cagaacgtag ctaccaggca gttatctgtg accactgtgc
    34201 aagcatcgta gaagaaaact ttgcggaagc agtcgcagaa ggatttgaag agaaataaga
    34261 ttgaaaagtc taggcaaaat tcaatttgag aagaaaagac aactaatttt atagtctatt
    34321 aaacgcattg tatcacgttt ttgaacacct gatatgatgc gttttttatt tattttaaaa
    34381 atttgcgagg tatgactttt tatactcaac aagaatcaaa gagaaactta gcaagctaac
    34441 agtagtaaga taaaatagga atttgatatt agggataaga ttggtaaata gtgtaatatt
    34501 tttacaagaa taaatttata tagttatttc tggtttctga aaagtattat attatatttt
    34561 atttcatatt atacaaattt ttattttata atatcagaaa atactttttt tttaaaaagc
    34621 aaatatgata caattttatt tgaaaaaaaa taaaaaagga gattttatta tgaaatcaag
    34681 tggtatcgtc ggtcttgtgg gaggaatttt acttcttatt tgtccttttg tcttgttggg
    34741 aacagcggta aacacagctg ctacaactct taatggagga gctactgcag gggctttttc
    34801 aggtgttgcc ttactcttga atgccttgaa gattgcaaat cttgttcttg gtatcattgc
    34861 tattgtttac tataaaggag ataagcgtgt aggtgcagct ccgtctgtac taatgattgt
    34921 ttctggtgaa gttagtctca ttccattctt aggatgggtt ggggggattc ttgctattat
    34981 cggaggatct ctattccttg caacattgaa gaaattcaaa tcagaagaat aaaaggtatt
    35041 ttagcatgaa aagaacaaaa aagtttatcg gtataggagt agctctatta tctctttctc
    35101 ttctagttgc atgtggaaca taaagttcaa agaatacttc aacaagtaat gatgagaaga
    35161 cagtagcaac atccaatagt tcaaaagaaa caatcacttt cgatacaccg gttgtaacag
    35221 acgatgcgat tgaatcaata cgcacttatg cagattatat agatctttat aaaaatattt
    35281 ttgatgatta ttttactaaa actgaggaag gtttcaaagg cacagctatg gaaaataatg
    35341 actcgtttac taaactaaaa gagtcaactc aaaaattatt cgatgcgcag aaaaaaaggt
    35401 taaataatga agatagaata gaaacaacca aaaacaatgt gattgccaaa cattgtcaaa
    35461 cagtcctttc ctttttggtt ttgactagct tttttgtgaa aaattgtgta aaatagaata
    35521 gataaacgag gggaaacctc ggaaaattta aaggagaatc catctaatgg taaaattggt
    35581 ttttgctcgc cacggtgagt ctgaatggaa caaagctaac cttttcactg gttgggctga
    35641 tgttgatttg tctgaaaaag gtacacaaca agcgattgac gctggtaaat tgatcaaaga
    35701 agctggtatc aaatttgacc aagcttacac ttcagtattg aaacgtgcta tcaaaacaac
    35761 taacttggct cttgaagctt ctgaccaatt gtgggttcca gttgaaaaat catggcgctt
    35821 gaacgaacgt cactacggtg gtttgactgg taaaaataaa gctgaagctg ctgaacaatt
    35881 tggtgatgag caagttcaca tctggcgtcg ttcatacgat gtattgcctc caaacatgga
    35941 ccgtgatgat gagcactcag ctcacacaga ccgtcgttac gcttcacttg acgactcagt
    36001 tatcccagat gctgaaaact tgaaagtgac tttggaacgt gctcttccat tctgggaaga
    36061 taaaatcgct ccagctctta aagatggtaa aaacgtattc gtaggagctc acggtaactc
    36121 aatccgtgcc cttgtaaaac acatcaaagg tttgtcagat gacgagatca tggacgtgga
    36181 aatccctaac ttcccaccat tggtattcga attcgacgaa aaattgaacg tcgtttctga
    36241 atactacctt ggaaaataaa aaattgtaag tctagaattg atttctaggc tttttatgtt
    36301 agtatggaag tatgataagg aataaaaaac aagattatgt actggcctac aagcaaccag
    36361 cttcaaccac ttacatgggt tgggaagaag aagctttacc gataggcaat ggttctttag
    36421 gagcaaaagt atttggcctt ataggggctg aacggattca atttaatgaa aaaagtctct
    36481 ggtctggagg tccacttcct gatagttcag attatcaggg tggaaatctt caggatcagt
    36541 atgtttttta gctgagattc ggcaggcttt ggagaagaga gattacaatc tggctaagga
    36601 actggctgag cagcacctaa ttgggccaaa aacgagtcaa tatgggacct atctgtcttt
    36661 tggggatatt cacattgagt tcagccagca aggtacgact ttgtctcagg tgacggacta
    36721 tcagagacag ctgaatatta gtaaggcact tgcgacgact tcttatgtct ataagggaac
    36781 gcgatttgaa cgtgaagctt ttgcgagttt tccagatgat ctcttggttc aatgttttac
    36841 taaggaaggg ttggaaactc tagattttac tatagaacta tccttgacct gtgatttggc
    36901 ttctaatgga aagtatgaac aggaaaagtc tgattacaag gagtgtaagt tggatattac
    36961 tgattctcat atcttgatga agggaagagt taaggataat gatctgcggt ttgctagtta
    37021 tctagcttgg gaaacggatg gagatattag agtttggtca tatagggttc agatatcagg
    37081 agccagttat gccaatctct tcttggccgc taagacggat tttgcccaaa atcctgctag
    37141 caattatcgc aagaaactag atttagagca acaggtgaga gacttggtgg acacagctaa
    37201 agaaaagggc tatacccaat tgaaatcaag gcatatcgag gactaccaag ccttattcca
    37261 gcgtgttcaa ttggatttgg aagctgatgt tgacgcatcc actacagatg atttgttaaa
    37321 aaattataag ccacaagaag ggcaggcttt ggaggagctg ttcttccagt atggacggta
    37381 tttattgatt agttcgtcca gagactgccc agatgctcta ccagctaacc tacagggagt
    37441 ctggaatgcg gtcgacaatc ctccttggaa ttcggactat cacttaaatg tcaatctgca
    37501 gatgaattat tggccagcct atgttaccaa tctcctagag gcggtctttc cggtcatcaa
    37561 ctatgtagat gatttgcgtg tctatggtcg tctagcggct gtaaagtatg caggaatcgt
    37621 ctctcaaaaa ggtgaggaaa atggttggtt ggttcatact caagcgactc cctttggttg
    37681 gacggcacct ggttgggatt actattgggg ttggtcacca gctgccaatg cgtggatgat
    37741 gcaaaccgtt tatgaagcct attcatttta tagggaccaa gactatctca gagagaaaat
    37801 ttatcccatg ttgagggaaa cggttcgttt ttggaatgcc tttttacata aggatcagca
    37861 ggcgcagcgt tgggtgtctt ctccgtctta ttccccagaa catgggccga tttcgattgg
    37921 caatacttat gaccaatctc taatttggca gttatttcat gattttattc aggctgctca
    37981 ggaattggga ctggatgagg acttgttgac tgaggttaag gagaagtctg atttactaaa
    38041 tcctttgcaa atcactcaat ctggtcgaat cagggagtgg tatgaggagg aagagcagta
    38101 ttttcaaaat gagaaagtgg aggcccagca tcggcacgct tcccatctag tgggactcta
    38161 tcctggcaat ctctttagct acaagggaca agagtatatt gaagcggcgc gtgctagcct
    38221 caatgatcgt ggagatggcg gcacaggctg gtccaaggct aataagatca atctctgggc
    38281 gcgtttggga gatggcaatc gagcccataa attattggca gagcagttaa agacatccac
    38341 cttgccaaat ctttggtgta gccatcctcc ttttcagata gatggtaatt ttggtgctac
    38401 tagtggcatg gcagaaatgt tactccagtc tcatgcagct tatctggtac ctctagctgc
    38461 cctacctgat gcttggtcaa caggttctgt ttcaggctta atggcacgtg gacattttga
    38521 agtgagcatg agctgggaag ataaaaaact cttacagttg accattttat caaggagtgg
    38581 aggagatttg cgagtttctt atccagatat tgagaagagt gtgattaaaa tgaatcaaga
    38641 aaaaataaaa gcgaaatgca tggggaaaga ttgtatttcg gtggcaacag cagaaggtga
    38701 tcttgttcaa ttttattttt aagaagatgt tataaggcag taatttgaaa ctgcctttta
    38761 ataaggattt aagaatataa gcagttttca actagttgaa aaagcgttat aatgataata
    38821 ggaagtaata ctcaatgaaa atcaaagagc acaaacaagg aagctagccg caggttgctc
    38881 aaaacagtgt tttgaggttg cagatggaag ctgacgtggt ttgaagagag attttcgagg
    38941 agtataattt gtttgataga gggtgggtct gatggcttat attgagatga aacactgtta
    39001 caagcgttat caggttgggg acacggagat tgtggccaat cgtgatgtga attttgagat
    39061 tgaaaagggg gagctggtta ttatccttgg tgcttcaggt gcaggcaagt caacagtgct
    39121 taaccttctt gggggaatgg ataccaatga tgaaggggaa atctggattg atggtgttaa
    39181 tattgcggat tatagttccc accagcgcac caattaccgt agaaatgatg tggggtttgt
    39241 ttttcagttt tataatctag tttctaatct gacagctaag gaaaatgtgg aactggcttc
    39301 tgaaattgtg acagatgtct tgaatcctga tcaggtcttg acagatgtag gtctggctca
    39361 tcgtctaaat aactttccag cccagctttc tggaggggag caacagcgag tctccattgc
    39421 acgcgcggta gccaaaaatc ctaaaattct tctttgtgat gaacctactg gagccttgga
    39481 ttatcagacg ggcaagcagg ttttgaaaat tctccaagat atgtctcgtc aaaagggagc
    39541 gacggtgatc atcgtgactc ataatggagc tttggcgccc attgctgatc gcgtgattca
    39601 tatgcacgat gccagtgtca aggatgtggt gctcaaccag catcctcagg atattgacag
    39661 tttggagtac tagtatgatc aagcgaaaaa cttattggaa ggacttaatt cagtccttca
    39721 caggctccaa ggggcgtttt ttatccatct tgatcctgat gatgttggga tctctagcct
    39781 tagtaggcct caaagtaacc agtcccaaca tggaggcgac agctaatgct tatttaacaa
    39841 ctgctcaaac cttggatttg gcagtcatgt ctaactatgg cttggatcaa gcagaccaag
    39901 aagaactaaa acagacggag ggcgcagagg tcgagtttgg ctatttgaca gatgtgacta
    39961 tggataatgg gcaggatgcc attcggctgt actccaaacc agagcgaatt tcaacctttc
    40021 agctaagaaa gggacgactt cctcagtcag acaaggaaat cgctttggcc actcatttgc
    40081 aaggccaatg cagcgtggga caggagatta gttttaaaga aaaagaagag ggtcattcct
    40141 ctttaaaaga ccatacttat accattactg gttttgtgga ttcggctgaa atcctctccc
    40201 agcgagatat gggctacgca ggaagtggaa gtgggactct gacagcctat ggggtgattt
    40261 tacctagtca gtttgatcag aaagtctaca atatagctcg tttgaaatat caagatttag
    40321 caggtttaaa tgccttttca tcagcttatg aagaaaaatc caagcaacat caggaagacc
    40381 ttgaacaaac tttatcagat aatggcaagg tacgtctgca acttttgaaa aaagaaggac
    40441 aagagtctct agacaagggg caagagaccc ttgacaaggc tcagactaat ttgcaggaag
    40501 gcaagcgtcg tttagcagct gctcaagctc gtatacaggc tcaagaaagt caactagcct
    40561 tgtttcctca agttcagaga gagcaggcta gtgctcaact tacccaagcc aagcaggaat
    40621 tgggcaagga agaagacaaa ctaaagcaag ctgaacaaaa tctagcccaa gaaaaggaaa
    40681 aattagaaaa acatcagcaa gtcttggacg atttggcgga gccaaggtat caggtctata
    40741 atcgtcagac catgccaggt ggtcagggct atcttatgta tagcaatgct tcatccagta
    40801 ttcgagcagt gggcaatatc tttcctgtgg tactttatgc cgtagcagcc atggtgacct
    40861 ttacgaccat gactcgcttt gtagacgaag agcgaactca tgcagggatt tttaaggcct
    40921 tgggttaccg tagtaaggat attatcgcca agtttctcct ttatggacta gtagctggga
    40981 ctgtcggaac ggctctaggt agtatacttg gtcattattt gctagccagt gtaatttcaa
    41041 gtgtcattac aaaaggcatg gtggtgggag aaacccagat tcagttctat tggacctata
    41101 gcttactagc tcttgtcttg agctggttgg cgagtgtgtt accagcctat ctggtggctt
    41161 ggagggaact tcatgccgaa gcagcccagc ttctacttcc taaacctcct gtcaaaggag
    41221 ctaaaatctt attggagcgt atcggtttta tctggcgtcg tctcagtttt actcataagg
    41281 taacagcccg caacatcttt cgttataagc agagaatgtt gatgacaatc tttggtgtgg
    41341 caggttctgt agctctgctc tttgcaggtt tgggaatcca atcttctgta gcaggagttc
    41401 cgtctaaaca gtttcaacaa atccaacagt atcagatgct tgtctctgaa aatcctagtg
    41461 cgaccgatca ggacaaggta gagctagcag aagtgttgaa agggcaggag atactagcct
    41521 accagaaaat ctattctaaa acgctagaca aggatttcaa aggcaaggct ggtcttcaaa
    41581 acattactct tatgatgata gagaaggaag atttgactcc ctttatccat cttcaacatc
    41641 atcagcagga gctgacatta aaagatggca tcgttattac agctaaactc gcccagctgg
    41701 caggtgtcaa ggttgggcag actttagaaa ttgaaggtaa ggaactaaag gtcgctgcta
    41761 ttactgagaa ctacgttggt cactttattt atatgagtca ggctagctat gagcaacttt
    41821 acggacagct accccaagcc aacacttatc tggtctcatt aagggatacc agtgcaacta
    41881 gtatcgaaag tcaggcgggc ttgcttatga gtcaatctgc ggtgtccagc gttgtccaaa
    41941 atgcttcagc cattcgactc ttcgactctg tcgctagctc actcaatcag accatgacca
    42001 tcttggtcat cgtatcggtt ctattagcta ttgtcatcct ttacaatctg accaatatca
    42061 acgtagctga gagaatccgt gaactctcca ctaccaaggt tcttggtttt cataataatg
    42121 aagtcaccct ctacatttac cgtgagacga ttgtgctatc ccttgtggga atcgtacttg
    42181 gtctggtagc tggtttctat ttacaccaat ttttgattca aatgatttcg cctgcgacta
    42241 ttctctttta tccgcaggta ggctgggaag tctatgtaat cccagtggca gcagtaagca
    42301 tcattttgac cttgcttggt ttcttcgtca attattatct gagaaaggtt gatatgttag
    42361 aagccctgaa atctgtagag taaggtagtt atttttagct gattgaactt ctatttacta
    42421 atattcaaaa atcctccgtt tcaaagagca gggaactctt tgtgacagag gattttttct
    42481 atagggcttt agcagctgca attgcggctt cgaagtttgg ctcagaattg atattatcca
    42541 cgtattcaac gtagcgaatc gtattgtcag tatcgaggac aaagactgcg cgtgctaata
    42601 ggtgccattc gttgatcaag agggcataat cgcgcccgaa agaatggtca aagtagtctg
    42661 aaagcataat ggcattgtca aggccttcag caccgcacca acgtttttga gcaaaaggta
    42721 ggtccattga aacagtcaat acgaccgtgt tgtccagtcc agccaattct tcattaaaac
    42781 gacgtgtttg agttgagcag atgcctgtat cgatagaagg aacgacactc aagacttttt
    42841 tcttgccatc aaaatcagcc agagattttt tagaaagatc tgttgtagta agagaaaaat
    42901 caagcgcctt gtcgccgact tgtagttgtt tacctgtaaa gctcacagga tttccgagaa
    42961 aagttaccat aggatactcc aatctttttt cttccattgt atctgaaaca gtcagaattt
    43021 tccaatgatt tgaccggaaa tgtgggcata gaaaaaacgc cagctcacat gagaatgacg
    43081 tttttcagag gcttattttg ccaatccttc agcaatcttg tcaaggttgt atttcatcat
    43141 gctgtagtag ctgtcgcctt ctttaccttg ttctgcgata gagtcagtaa agatttgtgc
    43201 gtagattggg atgtttgtgt cttgagaaac agttttcatt ggacggtcat ccacacttga
    43261 ttctacaaag agtgatggaa cttttgtttg gcgaagtttt tcaaccaagg tcttgatttg
    43321 ttcaggagtt ccttcttctt cagtattgat ttcccagatg taggcacttg ggacaccata
    43381 ggctttagag aagtatttga atgctccttc gctggttaca atgagtttct tttcagcagg
    43441 gatcttatta aatttatcct tactttcttt atcaagtttg tctaacttat cagtatattc
    43501 tttgagattt ttttcataga attctttatt gttagggtct ttggcgctca attgtttggc
    43561 gatattttta gcaaaaataa taccgttttc aaggttaagc caagcgtgtg ggtcttcttt
    43621 tcctttttca ttttgacctt caaggtagat aacatcaacg ccgtcgctga ctgcgaagta
    43681 gtctttgttt tcagttttct tggcattttc taccaatttt gtaaaccaag cattgccacc
    43741 tgtttcaagg ttgataccgt tatagaaaat caaatcagcc tcagaagttt tcttaacgtc
    43801 ttcaggaagt ggttcgtatt cgtgtgggtc ttgcccaatc ggaacgatac tatgaaggtc
    43861 aattttgtca ccagcaatat ttttagtaat atcagcgatg attgagtttg tagcaacaac
    43921 ttttagtttt tgaccagaag ttgtatcttt ttttccgcta gcacatgcta caagaatgat
    43981 tgcagaaaga aagagaacga gtaatgtacc taattttttc attagatcct ccaatttatt
    44041 agggctttgc cccttatttt aacaaatgtt tatttttcag tttcaaatat cgttgtttgg
    44101 gagcgataaa gaagctaatg agaaagaaac tagcagctgt aagcacgata ctagaacctg
    44161 ccgcaacatt aaaactatag ccaataaaga gtcccaaaac tgaagcagta gctccgaagg
    44221 ttgaggaaag gaaaatcatg cttttcagac tattagcata cagataagca gttgcagctg
    44281 gggtaatcag catggctaca atcaggatag ttccgacact ttgcatggct gtcacagaca
    44341 cgagagtcag gagtaccatg agaaggtagt gatagaaatt gacaggcatt cccatggctt
    44401 tagccaagag ttcatcaaag gaagttatca agagttgctt gaagaaaatc cagattaaca
    44461 agaggatggc tgcccccaca cccatagtaa taaacatatc cgtatcttgg acggccagga
    44521 tattaccaaa aaggatatgg aaaaggtcag ttgaactttt agcgacacca atcaagatga
    44581 taccgagggc taagaaagaa gaaaaggtaa tgccgatggc ggtatcgctt ttgataatcg
    44641 agtttccttt gatgtaggta atgatgatgg cagctagcaa tccaaagaca atggctccga
    44701 taaagaagtc aaggcccaag atgaaggaga gggctacacc tggtaagaca gcatgtgaaa
    44761 tggcatctcc catgagtgac atcccgcgta gaataatgaa acatcccacg gctccagcta
    44821 caatcccgac gacaatagct gttatcaagg cattttgtag gaaatggaat ttttgcaatc
    44881 catcgataaa ttctgcaatc ataggtcacc tccattgaaa aagagttgat taccgtaagc
    44941 ttcttttaga ttggtttcgg taaaagtttc ttttgttgga ccaaaggcaa tcacttctcg
    45001 attgacaagt aagacttgat cgaagtagtg gggaatcttg ctgaggtcgt ggtgaacgat
    45061 gagaaccgtc ttcccagctt ttttcaaatc tctcagcgta ttcatgatga tttcctcact
    45121 gacagagtca atcccagcaa agggttcatc caagaggata tagtcggctt cctgcaccaa
    45181 acatctggca atcaagaccc gctggaattg acctccagac agttgactaa tttgacgttc
    45241 agcgtagtca gctaggccga cgatttcaag ggcctcttgc actttcttcc aatgtttagc
    45301 ctttaaactt cgaaagagag gaatagaggg aaatagtcct aacgagacgc attccttgac
    45361 cttgatggga aagttgtagt cgatattgat tttttgttcg acataggcaa ttcggtgtaa
    45421 ggatttttta acttccttgt catcgagaaa tgcctgacct tgatgtggga taattcccaa
    45481 catacctttt aatagtgttg atttcccagc gccgtttgga ccaatgatgc cggtaattgt
    45541 tggtccatgg agcactagtg aaatatcctt aagtgccaac gtttctttgt aggagacact
    45601 gaggttttcg atacgtatca taaacttgta t
//
LOCUS       DAVKEV010000015        45065 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVKEV010000015 DAVKEV010000000
VERSION     DAVKEV010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45065
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.015"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(79..3756)
                     /gene="rpoC"
                     /locus_tag="VWZ68_000807"
     CDS             complement(79..3756)
                     /gene="rpoC"
                     /locus_tag="VWZ68_000807"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEU9371868.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(3789..7400)
                     /gene="rpoB"
                     /locus_tag="VWZ68_000808"
     CDS             complement(3789..7400)
                     /gene="rpoB"
                     /locus_tag="VWZ68_000808"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU9371869.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            7816..7886
                     /locus_tag="VWZ68_000809"
     tRNA            7816..7886
                     /locus_tag="VWZ68_000809"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7848..7850,aa:Cys,seq:gca)
     gene            complement(8084..9415)
                     /locus_tag="VWZ68_000810"
     CDS             complement(8084..9415)
                     /locus_tag="VWZ68_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEU9371870.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTNTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(9644..10468)
                     /gene="endA"
                     /locus_tag="VWZ68_000811"
     CDS             complement(9644..10468)
                     /gene="endA"
                     /locus_tag="VWZ68_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEU9371871.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(10507..10695)
                     /locus_tag="VWZ68_000812"
     CDS             complement(10507..10695)
                     /locus_tag="VWZ68_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU9371872.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(10688..11971)
                     /gene="murA"
                     /locus_tag="VWZ68_000813"
     CDS             complement(10688..11971)
                     /gene="murA"
                     /locus_tag="VWZ68_000813"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU9371873.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(11995..12225)
                     /locus_tag="VWZ68_000814"
     CDS             complement(11995..12225)
                     /locus_tag="VWZ68_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEU9371874.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(12283..13320)
                     /locus_tag="VWZ68_000815"
     CDS             complement(12283..13320)
                     /locus_tag="VWZ68_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEU9371875.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(13304..13792)
                     /gene="coaD"
                     /locus_tag="VWZ68_000816"
     CDS             complement(13304..13792)
                     /gene="coaD"
                     /locus_tag="VWZ68_000816"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEU9371876.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNVADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(13782..14321)
                     /gene="rsmD"
                     /locus_tag="VWZ68_000817"
     CDS             complement(13782..14321)
                     /gene="rsmD"
                     /locus_tag="VWZ68_000817"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEU9371877.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(14386..15378)
                     /locus_tag="VWZ68_000818"
     CDS             complement(14386..15378)
                     /locus_tag="VWZ68_000818"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEU9371878.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTSKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(15490..16173)
                     /locus_tag="VWZ68_000819"
     CDS             complement(15490..16173)
                     /locus_tag="VWZ68_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEU9371879.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(16229..16969)
                     /locus_tag="VWZ68_000820"
     CDS             complement(16229..16969)
                     /locus_tag="VWZ68_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEU9371880.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSPALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            17003..17281
                     /locus_tag="VWZ68_000821"
     CDS             17003..17281
                     /locus_tag="VWZ68_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEU9371881.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            17359..18285
                     /gene="yidC"
                     /locus_tag="VWZ68_000822"
     CDS             17359..18285
                     /gene="yidC"
                     /locus_tag="VWZ68_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU9371882.1"
                     /translation="MKSIKRFALSAMGAAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVHEELAKNPSKASAFST
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(18360..19154)
                     /gene="pflA"
                     /locus_tag="VWZ68_000823"
     CDS             complement(18360..19154)
                     /gene="pflA"
                     /locus_tag="VWZ68_000823"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEU9371883.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(19280..20530)
                     /locus_tag="VWZ68_000824"
     CDS             complement(19280..20530)
                     /locus_tag="VWZ68_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEU9371884.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(20597..21424)
                     /gene="purR"
                     /locus_tag="VWZ68_000825"
     CDS             complement(20597..21424)
                     /gene="purR"
                     /locus_tag="VWZ68_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEU9371885.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(21691..22632)
                     /locus_tag="VWZ68_000826"
     CDS             complement(21691..22632)
                     /locus_tag="VWZ68_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEU9371886.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            complement(22622..23878)
                     /locus_tag="VWZ68_000827"
     CDS             complement(22622..23878)
                     /locus_tag="VWZ68_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEU9371887.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(23880..24542)
                     /locus_tag="VWZ68_000828"
     CDS             complement(23880..24542)
                     /locus_tag="VWZ68_000828"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEU9371888.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(24505..25161)
                     /locus_tag="VWZ68_000829"
     CDS             complement(24505..25161)
                     /locus_tag="VWZ68_000829"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU9371889.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVANPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(25172..26050)
                     /gene="rsgA"
                     /locus_tag="VWZ68_000830"
     CDS             complement(25172..26050)
                     /gene="rsgA"
                     /locus_tag="VWZ68_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEU9371890.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFFNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETHKKVSKKIPK"
     gene            complement(26052..26924)
                     /gene="rsmA"
                     /locus_tag="VWZ68_000831"
     CDS             complement(26052..26924)
                     /gene="rsmA"
                     /locus_tag="VWZ68_000831"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEU9371891.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFACLADALKGQGL"
     gene            complement(27055..27363)
                     /locus_tag="VWZ68_000832"
     CDS             complement(27055..27363)
                     /locus_tag="VWZ68_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371892.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(27356..27997)
                     /locus_tag="VWZ68_000833"
     CDS             complement(27356..27997)
                     /locus_tag="VWZ68_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9371893.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRMIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(27999..30029)
                     /locus_tag="VWZ68_000834"
     CDS             complement(27999..30029)
                     /locus_tag="VWZ68_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9371894.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREKVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSI
                     LGLGILWYQGALFMATVQLVIIALLLYGLILAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQYSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(30298..31197)
                     /locus_tag="VWZ68_000835"
     CDS             complement(30298..31197)
                     /locus_tag="VWZ68_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9371895.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(31269..31829)
                     /gene="rnmV"
                     /locus_tag="VWZ68_000836"
     CDS             complement(31269..31829)
                     /gene="rnmV"
                     /locus_tag="VWZ68_000836"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEU9371896.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMMVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSCKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(31829..32602)
                     /locus_tag="VWZ68_000837"
     CDS             complement(31829..32602)
                     /locus_tag="VWZ68_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEU9371897.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(32907..33800)
                     /locus_tag="VWZ68_000838"
     CDS             complement(32907..33800)
                     /locus_tag="VWZ68_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU9371898.1"
                     /translation="MVAQDPKAQDSTKLTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(34084..34218)
                     /gene="rpmH"
                     /locus_tag="VWZ68_000839"
     CDS             complement(34084..34218)
                     /gene="rpmH"
                     /locus_tag="VWZ68_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEU9371899.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(34363..35577)
                     /locus_tag="VWZ68_000840"
     CDS             complement(34363..35577)
                     /locus_tag="VWZ68_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9371900.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(35733..36027)
                     /locus_tag="VWZ68_000841"
                     /pseudo
     CDS             complement(35733..36027)
                     /locus_tag="VWZ68_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            36189..36641
                     /locus_tag="VWZ68_000842"
     CDS             36189..36641
                     /locus_tag="VWZ68_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEU9371901.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(36676..38064)
                     /locus_tag="VWZ68_000843"
     CDS             complement(36676..38064)
                     /locus_tag="VWZ68_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9371902.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            38130..39092
                     /locus_tag="VWZ68_000844"
     CDS             38130..39092
                     /locus_tag="VWZ68_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEU9371903.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKNYMEG"
     gene            complement(39121..39279)
                     /locus_tag="VWZ68_000845"
     CDS             complement(39121..39279)
                     /locus_tag="VWZ68_000845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371904.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHVFEVVDETDEVS
                     NHTYGKAT"
     gene            complement(39343..40353)
                     /gene="ccpA"
                     /locus_tag="VWZ68_000846"
     CDS             complement(39343..40353)
                     /gene="ccpA"
                     /locus_tag="VWZ68_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEU9371905.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(40778..41377)
                     /locus_tag="VWZ68_000847"
     CDS             complement(40778..41377)
                     /locus_tag="VWZ68_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9371906.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(41379..42476)
                     /locus_tag="VWZ68_000848"
     CDS             complement(41379..42476)
                     /locus_tag="VWZ68_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9371907.1"
                     /translation="MLERLKSIHYMFWVSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGIMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VEQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     EAMTSMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(42476..43213)
                     /locus_tag="VWZ68_000849"
     CDS             complement(42476..43213)
                     /locus_tag="VWZ68_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9371908.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GEPANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(43215..44099)
                     /locus_tag="VWZ68_000850"
     CDS             complement(43215..44099)
                     /locus_tag="VWZ68_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9371909.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFILTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(44086..44280)
                     /locus_tag="VWZ68_000851"
     CDS             complement(44086..44280)
                     /locus_tag="VWZ68_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371910.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIHGALGFGFM
                     IFVVFPMGMEWLKGESHDGG"
     gene            complement(44277..44483)
                     /locus_tag="VWZ68_000852"
     CDS             complement(44277..44483)
                     /locus_tag="VWZ68_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371911.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT        12880 a        10500 c         8550 g        13135 t
ORIGIN      
        1 tttaccacat ttcgtggaaa aatggagaaa gttttcagaa gagagaatga gagaaccctc
       61 gggttctctc attctctctt attctactgt ttcttccaca gtttcaacgg cagtatccac
      121 aactacttct gttgtttctt catttccttc ttcctctact ggaggattaa ggtattcttc
      181 ttcgttgaca gcatgtggtt caaggttacg gtaacgggcc ataccagtac cagctgggat
      241 gatcttaccg atgataacat tttctttaag tccaaggaga tggtctttct taccacggat
      301 agctgcgtca gtaaggacac gagttgtttc ctggaaggaa gccgctgaca agaaactgtt
      361 tgtttcaagt gaggctttgg taattcccat aaggactggg cgacctgtcg ctggaactcc
      421 acctgcgata aggacatctt tgttggcatc tgtaaagtca ttgatatcca tgagggtacc
      481 catgagaaga tctgtatcac ctggatccat gacacggact ttacggatca tttgacgaac
      541 cattacctcg atgtgtttgt caccgatttc taccccttgg ctacggtaaa ctttttgtac
      601 ttcaccgaga aggtacgttt caactgacaa gacatcacga actgcaagga gacgttttgg
      661 ttggatagaa ccttctgtca gagcagcacc acgcgctact tggcccccaa cttcgacacg
      721 catacgagct gtaaatggaa cgacatattc accttcgcca gtttcaccct taacaaagac
      781 tttcttggta cgagttgatg catcttcttc gatagcagta acttgtcctt taacctctgt
      841 aataaccgct tcccctttag gattgcgggc ttcaaagatt tcttggacac gaggaagacc
      901 ctgagtgata tcggtatttg aggcaacccc acctgtgtgg aaggtacgca ttgtaagctg
      961 tgtaccaggt tccccgatag attgggcagc gattgtacca actgcttcac caacttcaac
     1021 cgcatcacca gtcgccaagt tgataccgta acagtgacgg cagacaccgt gacgagtgtt
     1081 acatgtaaat acagaacgga tagtcacttc ttccacacca gcattgacaa tttcacgcgc
     1141 cttgtcttct gtaatcaatt catttggacc aataatcact gcaccagttt ctggatgttt
     1201 aacagttttc ttagtgtaac gaccgttgag acgctcttcg agagactcga tcatctcttt
     1261 tccttctgcg atagaacgga tcaagagacc acggtcagtt ccacagtcgt cctcacggat
     1321 gataacgtct tgggcaacgt cgaccaaacg acgagtcaag taacctgagt cggctgtctt
     1381 aagggccgta tcggtcatac ctttacgagc accgtgagtt gagaagaaca tttccaatac
     1441 cgacaaacct tcgcggaagt ttgaaaggat tggcaattcc atgatacgtc cattcggagc
     1501 agccatcaga ccacgcatac cggcaagctg tgagaagttt gagatgttac cacgggctcc
     1561 agagtccatc atcataacga ttgggttctt aggatcttga ttagcaatca agcgtttctc
     1621 aagtttttca cgggcagcac gccattcagc tgtaacagca ttgtaacgct cgtcgtctgt
     1681 gatcatacca cgacggaatt gtttggtgat ttgttcgaca cgtttgtgtg attcttcaat
     1741 gatttcagcc ttgtcatcaa cgactgggat atcggcaata cccactgtca atcctgcaag
     1801 agttgagtgg tggtaaccga ggttcttcat gcggtcaagt agggcagaag tttctgtcgt
     1861 acggaaacgt ttgaagattt cagcgatgat atttccgagg tttttcttct tgaatggagg
     1921 gttgagctca agattgctga tagcttcctt gatagctcca ccaagtggca agaagtattt
     1981 agctggaaca ccttctgtca agttggcatt gtttggttct tgcaagtatg gtagcccctc
     2041 tggcatgata tcgttgaaga gaattttacc aactgttgta agcaagacct tatgtctttg
     2101 ctcttctgtc caaggcttgt tgaggctgtc tgttgcgata ccaacacgtg agtggaggtg
     2161 aacataacca ttgcggtaag ccataaccgc ttcgtcacgg tctttgaaga ccattccttc
     2221 accttcgcga ccagcttctt ccatggtcaa gtagtagtta cccaaaacca tgtcctgaga
     2281 tggagtaact accggtttcc catctttcgg gttcaagatg tgctcagcag ctagcatgag
     2341 gatacgagct tctgcttgtg cttcttctga aagtggtacg tggatggcca tttggtcccc
     2401 gtcaaagtca gcattgtagg cttcacagac aagtgggtgc aagcgaagag ccttaccatc
     2461 aattaagact ggctcgaagg cttggatacc caaacggtga agggtcggtg cgcggttcaa
     2521 aagcactggg tgttctttaa tcacttcttc aaggatatcc cagatacgct catctccgcg
     2581 ttccaccaag cgtttagctg ctttgacgtt ttgcacgata tcacgggcaa cgatttcacg
     2641 catgacaaat ggtttaaaga gttcaatcgc catttcacgt ggcacaccac attggtacat
     2701 cttaagagtt ggaccaacgg cgataacgga acgtcctgag aagtcaacac gtttaccgag
     2761 caagttttga cggaagcgtc cttgtttacc tttaagcatg tggctcaatg atttcaatgg
     2821 acggctacct ggtcctgtga ttggacgacc acgacgacca ttgtcaatca aagcatcaac
     2881 tgcttcttga agcatacgct tctcattttg aacgatgata cctggtgcat ttaactcaag
     2941 caaacgagcc aaacggttgt tacggttgat aacacggcgg taaaggtcat tcaagtcaga
     3001 tgaggcaaaa cggccaccat ccaactgcaa cattggacga agatctggtg ggataaccgg
     3061 aaggatgtta agaatcatcc attcaggttt gtttccagac ttgtaaaagg catccaaaac
     3121 atccaaacga cggatggctt tgacacgttt ttgtccagta gctgttttca attcttcttt
     3181 gagttcagca atttcttttt caagatctac ttgcttcaaa aggtcttgga tggcttccgc
     3241 acccatcttg gcaacaaatg aaccataacc atattcacgc aagcgctctc ggtattcgcg
     3301 ctctgtcatg atagacttgt gctcaagtgg tgtatcctta ggatcaatca ccacataagc
     3361 cgcaaagtag ataacttcct cgagggcacg agggctcata tcaagggtca agcccatacg
     3421 gcttggaatc cccttgaagt accagatgtg agatacagga gctttcaatt cgatatgtcc
     3481 catacgctca cgacgaactt tcgtacgcgt tacttcaacc ccacagcggt cacaaacaat
     3541 tcctctgtaa cgaatgcgtt tgtacttacc acaagcacat tcccagtctt ttgtaggacc
     3601 aaagatcact tcatcaaaga gtccttcacg ttctggtttc aaggtacgat aattgattgt
     3661 ttcaggtttt ttgacttctc cataagacca tgaacggact ttacttggag aagctagggt
     3721 gatttgcata cttttaaaac gatttacatc aaccactatt tcttcccttt ctattctaag
     3781 tgaactgctt attcttgttc agcagcttct tctgttgctt ccgcttttgt tgctttctca
     3841 gcttcttcag cttcaaaggc tgctttagcc tcttgggctg ctttttcgcg ggctttttca
     3901 aggtcatcta cgtggatgac atcttcgtcc attccttcat ccaagtcgcg aagttccact
     3961 tcttggtcat cttcgtctag gacacgcatg tcaagaccaa gagattgcaa ttctttgaca
     4021 agaactcgga aggattctgg aacacctggt tttggaattg gtttgccttt tgtaatagct
     4081 tcataggctt tcaaacgtcc gttgatatcg tccgacttgt aagtcaagat ttcttgaagg
     4141 acatttgacg caccgtaggc ttcaagagcc caaacctcca tctcaccgaa acgttgtcca
     4201 ccaaactgag ctttacctcc gagtggttgt tgggtaacag ttgagtaagg tccgactgaa
     4261 cgcgcgtgca atttatcgtc aaccatgtgg tggagtttga tcatgtacat gactccaaca
     4321 gaaacacggt tatcaaatgg ttcacctgta cgtccatcgt aaaggattgt cttggcatcg
     4381 ctatccatac ctgcttcttt aacagttgac caaagatctt cagaacttgc tccatcaaag
     4441 actggtgtcg caatgtgaat accaagagta cgagctgcca taccaaggtg aagctccata
     4501 acctgaccga tattcatacg tgatggcacc ccaagtgggt tcaacatgat gtcgactgga
     4561 gttccgtctg gaaggtaagg catgtcttct acaggaacga tacgagagac aacccctttg
     4621 tttccatgac gtccggccat tttatctccg accttaatct tacgtttttg agcgatgtaa
     4681 acacgaacca acatgttaac acctgattgc aactcatctc catttacacg tgtaaagatc
     4741 ttaacatcac gaacgacacc atcggcaccg tgtggtacac gaagagaagt atcacgcact
     4801 tcacgagact tgtctccaaa gatagcgtgc aagagacgtt cttcagctga aagatctttc
     4861 tcacccttag gtgttacttt acctacaaga atatcacctt ctttaacctc agcaccaata
     4921 cggataatcc ccatttcgtc aaggtctttg agggcatctt caccaacgtt tggaatttcg
     4981 cgagtgattt cttcaggccc aagctttgta tcgcgcgttt ctgattcgta ttcttcaagg
     5041 tgaacagatg tgtagacatc gtccttcacc aagcgttcgc tcatgataac ggcatcctcg
     5101 aagttgtaac cttcccaagt catgtaggca acgattgggt tttgtccaag cgccatttct
     5161 ccattttcca tagaaggtcc gtcagcgatg aaatcgcctt tttcaacgac atcaccaact
     5221 tttacgagag tgcgttggtt gtaagcagta cctgagtttg aacgacggaa tttttggatg
     5281 tggtaaacat ccaatgaacc atcttcacga cgaacttcta ccttgtcagc atctgcgtaa
     5341 gtaactttac catcatactg agcaatcaca gccgcaccag aatcgtgggc tgcttggtat
     5401 tccataccag taccaacgta aggtgcctga ggattaatca atggcacagc ctgacgttgc
     5461 atattggctc ccatgagggc acggttggag tcatcgtttt ccaagaaagg aatacatgct
     5521 gtcgcaacgg caactacctg ttttggtgaa acgtccatgt agtcaacaat attagctgga
     5581 tactcttggt tgaccccttg gtgacgtccc atgacaatct tctcagcaaa ggttccatct
     5641 tcattcagac gagagttagc ctgagctaca gtatattcat cttcttcatc agctgtcaac
     5701 caaacaattt cgttcgtgac aacacctgtt tcacggtcaa ccttacggta tggtgtttga
     5761 acaaaaccat atttgttcaa gtgtccgtaa gatgacaagt tattgatcaa accgatgtta
     5821 ggtccttcag gtgtttcgat tggacacata cgaccatagt gagtgtagtg cacgtcacgc
     5881 acttcatatc cggcacggtc acgagtcaaa ccaccaggtc ctaaggctga caaacggcgt
     5941 ttgtgagaca actcagaaag cgggttgtgt tggtccatga actgtgacaa ctgtgatgaa
     6001 ccaaagaatt ctttaactgc agctgttaca ggacggatat tgataatttg ttgtggtgtc
     6061 aagacttcat tgtcctgaac agacatacgt tcacggacat tacgttccat acgagaaagt
     6121 cccaaacgta cttggttggc aagcaattca ccaaccgcac ggatacgacg atttccaagg
     6181 tggtcgatat catctacacg gccaagtcct tcagccaagt tgaggaagta gctcatctca
     6241 gcaaggatat ctgcaggagt caccgtacga accttgtcat ctgggttagc attaccaatg
     6301 atcgttacga cgcgatctgg atcagttgga gcaacaacct tgaatttttg aagaacaaca
     6361 ggctcagtca caacggctgc atcgtttggg atgtagacaa tcttgttcaa gtcgccatcc
     6421 aaatggcttt caatgctttc aatcacgcta cgagtcataa tcgtaccagc ttctaccaag
     6481 atttctccag tttcagggtc taccaatggc tctgcaatgg tttggttgag caaacgtgtt
     6541 ttaacattga gttttttatt gattttgtaa cgaccaactg ctgccaagtc atagcgacgt
     6601 gggtcaaaga agcgagccac aagcaagcta cgtgagcttt cagctgtctt aggctcacct
     6661 ggacgaaggc gttcgtaaat ttctttcaag gcttcgtctg tacgagagtc cattggattc
     6721 ttgtggatat ctttttcaac agtgttgcga accaattcgc tgtcaccaaa gatatcaaag
     6781 atttcatcat cacctgagaa accaagagca cgaaccaagg ttgtaaatgg aatcttacga
     6841 gtacggtcga tacgagtgta ggtgatatct tttgagtcgc tttcaagttc caaccaagct
     6901 ccacggttag ggataacagt tgaaccatag cccaccttac catttttgtc tactttgtcg
     6961 ttaaagtaaa cacctggtga gcggaccaac tgagaaacga taatacgttc accaccattg
     7021 atgatgaaag tacccatttc tgtcatgatt gggaaatcac caaagaaaac ttcttgggtc
     7081 ttgatttcgc ctgtttcttt attgatcaaa cggaaggtta caaaaattgg tgctgagtag
     7141 ctagcatcgt ggatacgagc ttcttctagc gtgtattttg gttccttgat ttcatatcca
     7201 acaaattcca actccattgt gtctgtgaag tttgaaattg gcaatacatc ttcaaacact
     7261 tccttaagac cgtggtctag gaaagctttg aatgagtcag tttgaatttc aatcaaattt
     7321 ggtaagtcaa gaacttcttt gattcttgaa aaactacgac gggtacgatg tttcccgtat
     7381 tgaacgtcat gtcctgccaa gatgattctc ctttgtaaat aagttccaag ccttgtcaat
     7441 caggcttttc taatcgtcat atggttgtaa accccttatc accgtgtcct cttgacgaat
     7501 tttcagaatc tttaagcctc tgttacaaat gctcataatc ttgaaaaaaa gcacaaaaag
     7561 agcagctaaa tctgactttt tcagaagatt taactgctgt gagccttgtc tggacaatat
     7621 ttcagacaaa acctacgaca aatgattacc catattatac cctatttagc tagatttttc
     7681 aaggggtttc agtaggtttt tggtaaattt tttcccatag aaaacttggc atcacattcg
     7741 aatcacgcta tggtacaaaa aactgaaaaa actattgact gaaaatcatt ttcaaggtat
     7801 aataataaac gttaaggcgg tatagccaag tggtaaggca cggctctgca aaagcttgat
     7861 cgtcggttca aatccgtcta ccgccttcta taacttgatt tatcaggttt caaatgaaca
     7921 gaaagcccaa tttgaagggc ttttcttatt ttccctcgaa taaatacgta taactttaaa
     7981 aacttttgga gcgagtttgt ggcagagttc tttccatggc ataattccct tttgaaatca
     8041 attgaaaaaa gcttcgtcac gcctggtgac aaaagcctct agtttattct gtttcttctt
     8101 ctatttcgac ttctgtgatt tggactttta ccttggtaac acgtccattc ttcactttat
     8161 cattggttaa gataaactgt ttgttttggc tgaccaattc atagctgagt ttctcagtcg
     8221 ttggaatagt tcccactcct gtcaaataat aaccagcgat ggtatcaacg tcatcacttt
     8281 ccagttcaac atcaaagtaa ttattgaaat cattgagggt catagttcct tgaacaatgt
     8341 aggtatcctc gccaatctga tgaacatcta ttgctgcttt gtccgtttca tcatcaattt
     8401 caccaacaat ttcctctaag aggtcttcca aagtcaccaa accagccata ccaccgtatt
     8461 catccagcaa gattgccatt tgtctttggg tatttcgcag ttcttttagc aagtcatcca
     8521 caaaaatagt ttcaggtaca aaaagtggat cttgtaaaat tctcttccaa acaatattgt
     8581 caaaaccgtc cacaaagcct gccttaagga gactcttggt gtgaatgatt ccaattacat
     8641 tgtccttatc cccatcataa accgggatac gagaataatt ttgttttaaa atactttgga
     8701 taatggcttg actatcatcc tgaatatcca ccataaaggc atccgttcga ggcaccataa
     8761 cctctcgtgc catcagttca tcgagcgaaa agacaccttg tagcatctca atctcatcag
     8821 catccaatgt ttcttcacta tttgtcagca tataggcaat ttcatcacgg gtcatctttt
     8881 catccgcatc atcgaatgac ataggagtca aatggctcaa gaaattggtc gaagcagcta
     8941 aaagccaaac aaaaggactg actagttttc cgatcccaat gataatcggc gctgtacgaa
     9001 ttgccaaggc atcctttaga ttaagagcga ttctcttagg atataattcc ccaaaaacga
     9061 tggaaatata ggtcaaaaat gccaaggata gaaaagttgc cacggcttgt gctgtttcgc
     9121 cattcccaag ccaagaggca atcacacgtc ctagagtatt agttaaactc gcccctgata
     9181 agattgtaat cagggtgatt cctacctgaa tggttgataa aaagtggtta ggattttcta
     9241 gtaccttcag caggcggatg tagcgtctgt ctccttcttc cgccttttgt tcaactcggg
     9301 cacgattaag agaaaccatg gccatttctg tggctgagaa aaaggcattt aataccgtca
     9361 agataaacaa taaaacaaat tgtagcaaca aattctgact acttgggtct tccatagttc
     9421 ttctcctaaa atagtatctt atcctttatt atatcacaaa atttaatcca atacatatta
     9481 ttttttctta ccgtaacttc tcaaagtaac ttccatctct ctcccaaaac tggaagttag
     9541 ttttagaagt tgctattttt tcttagtacc tgttctagcc ctgcttaaac tagtaaaaag
     9601 aactcctaca tccataagtg acataggagt ttaggcttat cttttactga gttacagtta
     9661 cttctccagt tcggtaatcc agttgaagtc ccttttgaac attgggaact agaacattga
     9721 attccaattc tccatccgaa gacttggctt caatctgtga agctgaggga actaaatcct
     9781 cgtttgaagc gtagtaaagg gttacacggt aacggacacg cttgttttgg tccaaggctt
     9841 tacgcacctt gctttcatag tagttttgac cagtcgaata ctcggcttgt gcctgatttg
     9901 cccaggctgt ctgaacagca atgtttttag gattgcttgt tgaggcatca aaaccatcca
     9961 aaccaccgat taaggcatag cctaacaaat gacctctatc gactgcatgg gtataagagc
    10021 cctttagatt cttgacctga tgccaacctg gaggagtcca agaagttgaa ccattcccag
    10081 tttctttacg attcttgtac tgacgagtgg ccttagacaa gagggcatta gctacggttg
    10141 gaacagtttc cttgcccact gtctttgttt tattgtcagc gtagggctta cttgaaacct
    10201 tggcatctag atttgtttta ttaccattga cgataaaagc acctgagcca ttccactcca
    10261 gactcccctt tatttgactc ttgactgcgt ctgttaagac actctctgcc aatgcttgac
    10321 taggagcttc agacgcttgt tttttctgac taagattggt tttgggacta ttaggtgccg
    10381 acggcatctg cttgatataa tagctccctg tagacaaaag caataacact agcagtccga
    10441 ttagtgtctg tcttgttttt ttgttcatat ttctccttat ctttagaaaa aggctggttc
    10501 tccagcctaa tttcctgtaa atttatgaat caattcctgc cattttgctg gagacaggat
    10561 agcccatgga tcttgaccct tgcccaagat tccataacct accattaaac cgattcctag
    10621 agccagagta cctaaaatca gtactatgat gactaaaagt aaacgcttga ctacgtagct
    10681 tgatttctta ttcatcttca tcacttgcct caatccgctg aatcttagca cctagctgcg
    10741 ccaacttctc atggaaaccg tagtaacctc tatccaagtg aaccaattta ccgaccacag
    10801 tttctccctg tgctaccaaa cctgtcaaaa tcaaggctgc actggcacga aggtcagttg
    10861 aaagaacttc tgctccctgc aaaggctgtc caccaacaat acgagctgta tcacggataa
    10921 tctcagaatg caagcccatg cggcgcatct cttctaggtg ttggaaacga ttttcgaaaa
    10981 ctgtctccac catggttgat tcgccttttg caactgtcat caaggctgta aattgagcct
    11041 gcatatctgt tggaaatcct gggtggggca aggttttcac atgaacagct tttagatttt
    11101 ctagttgaga acgaacacga attccttcgt cttcttcaat tacttcaaca cccatttcaa
    11161 gtaacttggc aatcaaggga cggttgtgct cccagacagc gtctcgaatc aagacatcac
    11221 caccagtcat ggcagcagct accataaagg ttcctgcttc gatacggtct tggactacat
    11281 tgtgagtcgt accatgaagt ttctcaacac cagtaatggt tatagtctct gtaccagcac
    11341 ctttgacctt ggctcccatt tcattaagga gaatggctaa gtcaacaatc tcaggctcac
    11401 gcgcagcatt ctcaatcact gtcaccccat cagccagagt cgctgccatc atcaagttct
    11461 gcgttgcacc aacacttgga aagtccatat agatatgagc gccatgcaag cgttctgcct
    11521 tggcttcgat gtaaccagct gtctgactaa tcttaacccc catagcttcc agacctttca
    11581 aatgaagatc aataggacgg ctaccaatcg tacaaccacc tggcatggat accttggcat
    11641 gacccacacg ggcaaggatt ggccctaata caacgatgga ggcgcgcatc ttgctgacat
    11701 acttgtaagg ggcttcctca gtgatgtcgc cagtagcatc caccttgaca agatgagctt
    11761 cctcatcaaa gtcaaccttg gcattcaaac caccaactac ctgattcata ataaagacat
    11821 ccgacaaaat cggaacattc tgcaagacgg tctttccttc acttgctaga atagtcgctg
    11881 ccaacaaggg taagactgca ttttttgctc cctcgatcgt cacgcttcct accagacgat
    11941 tatcgccacc ttgaaccaca attttatcca tactcgtttc ctttactctt gatttcataa
    12001 taatcctcta agcgcttctt gccacaaatg atacaggcta ataaagaaag aactcaggat
    12061 gtagcctatg acaatgctaa aaaaggctac taataaacga acttttcttg tattatcatc
    12121 tgtcactttt aaaaccttct cccatctaac aagatccttt aaaaggtaaa aactcacata
    12181 aataaagaac atatgactac ttagagtgaa taataattga accatttgac tattatacca
    12241 tcttctctgt ttgtgcgcta gtttggaaac ttcactcaaa aattagggat tgtttttcaa
    12301 gtaatcaatc gcatcttgta gggttttaac gggcacgatt ttcatatccg tcttgattgt
    12361 tttagccgct tctagggctg tttggtagtt gtttttcgcg tccggatgcg ccttttgttc
    12421 ttcttcgcta acagggttat caggagcaaa gaaaatagca gcacctgccc tagccgaagc
    12481 tacaaccttc ttatcaatgc ctccaatgtc tcccacatta ccatcgcggt caatggtacc
    12541 tgtaccggca acaatacgac cattacgaag atctgggtga gctatttgag tatagatagc
    12601 tagactaaac atgagaccag cacttgggcc gccaatacca gctgttgaaa agctaattgg
    12661 gacattgctg attacctctg tacgatcaat caagccgatt ccaattccat ttttgccatt
    12721 ttccaaggtg ataatctttc cttctgcaga cttggtttgc ccatcctctt cataggtgac
    12781 cttgacggaa tcccctaatt tttgagaact gacgtaatca atcaagtctt tggaactatc
    12841 aaaggtctga tcattgactg ctgtgactgt atcagagata ttgagaatcc ctttaaaggt
    12901 tgaattatcc gtcacattca aaacataaac tccaaagtac ttgagttcga tatccttacc
    12961 agctgttttt agtccttgat acttggccat attttgcgat gtttgcatgt agaattgatt
    13021 gattcgcata aattcaacat cggaagaacc acctgtagtc tcctgagcac tacgaatatc
    13081 tgtaaaaggt gtcaaccaag cataaatcat atgagctaaa gtggcatgtt gaacaccaac
    13141 cgtaacgaat tgataggcac cagcttcctt atcttctgtg tcatttactt taaggacttg
    13201 gcgaatatct tccgaaccac ctggaacctc tatataataa ggcaagggca ctacaaatgc
    13261 caagaaagtc acaatcaagg ccgcaatgac gtataagggc catctaatct tttttttcat
    13321 ttcttatttc ctccaaaata ctctcgggaa catggcaggc aatatcctga ccaaacttca
    13381 aaagctctcg aacacctgat gaactgatat agagatgttc aggccggcta tgtaaataaa
    13441 tagtctctat atcagaagac agctgatgat tgtagtaatc aaaactagct tcatattgca
    13501 aatccgccac attcctcaac ccccgtacta ggaaagtagc ccccagtctt tttgcaacat
    13561 cgaccaccaa ttcatcatga gaagccacga cttcaacatt ttccaaatgt cccaaagcct
    13621 tttctagccc ccgtttacga ttttcaagag ggagaaatcc ttgtttgtgg ggattaaaaa
    13681 aaatacccac ataaagctta tcaaaaagtc tgctcgcccg ttcaatgata tccagatgcc
    13741 catttgtcat cggatcaaat gagcctgtga ataagccaat cttatctgac atagactgtc
    13801 accttactaa ttccataaat cttttccttc catataccca gacaggcaat ctcttctgga
    13861 agttcaacgg ccttatccgt ctcgcacaca accataacat cttcagaaaa aagctctctc
    13921 ttagccattt tttcaatatc tgctacgatt tgttccttgg catagggagg gtctaagaaa
    13981 acgaggtcaa attccccaga tacctgttcc aatgccctct ctgcatccat cttgaggagt
    14041 tgaaattttc caacttcctt ggtcatctgg atattttcag ccacgatggt ctgagcctta
    14101 cggtctcgct ccaccaaaac agcactggac atgccacgcg atactgcttc gatagataaa
    14161 ccaccactac ctgcataaag gtccaagact cgtccccctt caaagtaggg accaatcatg
    14221 ttaaaaatgg ctcccctaac cttatccgaa gtaggtcttg ttgtcttgcc ttctagtgtc
    14281 ttgaggggac gtcccccata gattcctgat acgattttca tactgtttat tataccaaat
    14341 tatagacaaa aagagaaaga aaaccgaacc ttgcggttcg attctctaca aaatattttc
    14401 gtaagtatcg cgtacttctt gaggccaaac acttgtttgc acttctccga tgtgtctctt
    14461 gcgaagtagg aacatggcca tacgagattg tccaattcct ccaccgattg tcaatgggaa
    14521 taggccattc aacaaagact tgtgccattc caattccaag cggtcttcat cacctgtaat
    14581 ttccacctga cgtctaagag tttcttcatc tacacgaatt cccatagaag acaactcaaa
    14641 ggctccacct aaagactcat tccagacaag aatatcacca tttagaccct tgtagccatt
    14701 ctcagactcg cttgtccagt catcatagtc tggtgcacgt ccatcgtgcg gtttaccatc
    14761 tggcaactcg ccaccgatac caatcaaaaa gacggctcca aattctttac aaatcgcatt
    14821 ttcacgttct ttcgatgtca agtctggata gcgttctacc aattcttctg tatggataaa
    14881 ggtgatttgt tttggcaaga tagactcgat gtcatagcga gcttcaacag ctagctcagt
    14941 caggcgaata gccttataaa tcttctcaac tgtttctttt agataaacga tgttacgctt
    15001 accatttggg ataaccttct cccagtccca ctggtcaaca taaacagagt gggttgcatc
    15061 caaggaatcc tcatctggac gaagggcttt catgtggaca aagagaccct ctccttcacc
    15121 aaagccaaaa cgagccaagg tgtggcgttt ccatttagca agtgagtgca ccacttcata
    15181 agtagcatca gggatttgga gaaccttgac cgatactgga ttttccacac cagacaggtt
    15241 gtcctgcatt ccgtcaccga ccttactcaa gataggacct tgaacttcga caacttctag
    15301 cttatctttc aaatactggg taaaagtgtt tttgacaaag gaaatttctt cttgttgatg
    15361 gataaaactt ttcttcatag acaactcctc aaaaatttaa taaacgtatt atacacctat
    15421 ttccaagaaa agaaaagaga aaatttaaaa aaaatcagtg tcactcaaaa cactgatttc
    15481 atagaccttt tagtcattgc gaccaaagat acgtagaata cttaggaaaa gattgataaa
    15541 atcaagatag atgctgagag ccattgacac cacccagcct gtcgctacac gaccttgtga
    15601 ttgttcatag gcgaggcgaa tcttttggtt atcccaagca atcaaccctg aaaaaaccaa
    15661 aaccatggct acactaatca tataatcaaa gaagccacta gccaagaaaa tattgactac
    15721 catagcaatc agtaaaccaa tgagagctgc catcattgct cgaccaatcc cactcaagtc
    15781 tttcttggta aagataccaa ctgccgccat gacaaagaag agaagggcgc tcgatacaaa
    15841 ggcagataaa actgtacccg gagtatagaa agccaccaca aaactaaggg taaagccgtt
    15901 taaaacggag taaagtaaaa atactggaag agcagctgga ctatttcttg aagccatgct
    15961 actggcaacg aaaaccaaag ccaactccgc aaaagtagca atggtcaacc agagacgccc
    16021 ctgcatcaac aagtaaacca actgagactg aaagaccgtc aacataaggc ctgataccaa
    16081 agcagatagt ccgattccca gaccaacaaa ggcataaacc ttagcgtaaa attgattgag
    16141 acctgcacgg tcatgtataa tagtgtgatt catccttttc tccttttctg tgaacatctt
    16201 tccttgatta taacaaaaaa agttaaaatt agcttaaatg gaagattaaa ataccggctg
    16261 caactgcaac attcaaactc tcggcctgcc ccttcatgct aatatggacc aactggtctg
    16321 cactttcagc cataagggga ctaattcctt gaccctcatt tcccataact agtacaaaat
    16381 tttctataga aggcagttct ctgtaatcaa cagaatcttt agatagggtt gttgctagca
    16441 ctgggatagc taccttttta gtttcgtcaa gaagcgctgg actagtcatc cggtaaatgg
    16501 gcagatggaa atgactacct tgcatggaac gtagggtttt gagactgtag atgtctgccg
    16561 acttatctga aacaatcact cctgtaaaac ctgctgcatc cgcagttcga atgatagttc
    16621 ctacattacc gggatcttgc acatcttcca aaaacaagaa cttgccctga ctcaaatcag
    16681 cttgtcctac ttcttctttt tgaaccaccg ccacaattcc ctgtggagtc tgagaatccg
    16741 ccaaatctag caaaatatcc tctgaaatcc agacagtttg cggaaaagca gctaactgat
    16801 ctcgataatt ttctagggca aagattttct caatcgtcac tccagcttgg acagcttctt
    16861 caaacaagtg ccagccttca atcaaatagg cagacttgcg gtattttttt tggtgtaatt
    16921 tcttggcatt ttttaccaca gaattggctt ttgaggttat aatagtcata gaaatattat
    16981 aacacaatca aaggggtttg gtatgcaaaa ggttagaatg attgcccaag gtagggtaca
    17041 gggagtcggc tttcgttggg gtgtttacag cttggcactt gaaattggtg gcatcacagg
    17101 tcgagtatgg aataacgacg atggcacagt ggaaatctta gcccaagcag actcatctgc
    17161 tatcatggca aaatttatcc aagaaatccg aaaaggaccg acaccttttt caaaagtaag
    17221 ctacttagat gtcaaactaa gcaactttcc tccctactct gactttaaaa tcgcaaatta
    17281 ggtctccaga actattgtat attttgtaaa aaaacagtag aatagaaagg tataattttt
    17341 aaagaaggaa taaaaacagt gaaatctatt aaacgttttg cactctcagc tatgggagcg
    17401 gctatgttgc ttgtcttgac tggttgtgtc aatgtcgata aaaccacagg tcagccaaca
    17461 ggatttattt ggaataccat cggagcccct atggctgaag ctatcaagta cttcgctact
    17521 gataaaggtc taggctttgg tgtcgctatc atcatcgtaa ccattatcgt gcgcttgatt
    17581 atcttgccac ttggtatcta ccaatcatgg aaggcaacgc ttcactctga aaagatgaac
    17641 gccctcaagc acgtccttga gccacaccaa acgcgtctca aagaagcgac tactcaagaa
    17701 gaaaaactcg aagcccaaca agctctcttt gctgctcaaa aagagcacgg tatcagcatg
    17761 tttggcggtg taggatgttt ccctatcctc cttcaaatgc ctttcttctc tgctatctac
    17821 tttgctgccc aacatactga aggggttgct caagcaagct acctaggcat tcctctaggt
    17881 tctccaagta tgattttggt tgcctgtgct ggtgtccttt actatcttca atcgctcctt
    17941 tcacttcacg gagtagaaga tgaaatgcaa agagaacaaa tcaagaaaat gatttacatg
    18001 agcccactca tgatcgtcgt cttctccctc ttctcaccag ctagtgtcac actttactgg
    18061 gttgtcggtg gtttcatgat gattctccag caatttatcg tcaactatat cgttcgtcca
    18121 aaacttcgca aaaaagtcca tgaagaactg gcaaagaacc catcaaaagc aagtgctttc
    18181 tcaacaccaa gtggacgaaa agacgttacc cctgaacaac caactgctat tacaagcaag
    18241 aaaaaacaca aaaatcgcaa cgctggaaaa caacgttcga gataagaaga aaaaggctta
    18301 gctgatttgc taagtctttt tgcaagtcaa aagcccgatg tttccatcag gcttcttttc
    18361 tatccatgta cacgtttcat ataatcttga taactttcgg tatccatgag ttttttagcg
    18421 ttcttgacgc gatctgctgt tggtggtttg actccttcga gggaatatgg aattccaagt
    18481 tcacgccact tgaactcacc catggtgtga taaggtagaa tttcaaactt atcaacattt
    18541 ttgagggtct tgacgaactt accaagttca atcaagtcat catctctgtc tgtcaatcct
    18601 ggaactagca cgtggcgaat ccagacaggt tttccaatat ctgatagata ctgggcacaa
    18661 gccaagatat ttttattggt ttggctagtg acaatcttgt gctgttcttc gttgatttcc
    18721 ttgatatcca aaagaaccaa gtcagtgaca gccatgagtt tgtcaaactt ctcaaggtaa
    18781 cgcggtttat tacggaaagg aagagcacag gtgtccaagg tacagtggat tccttgttcc
    18841 ttagccttgg tgaagagagc aatcaggaaa tcaatctgca agagagcttc tcctccactg
    18901 actgtaatcc cacccttatt tccccagaaa ccacggtagc gcaaggcctc tgtcaagaca
    18961 tcatctaccg tccgttcacg tgacttattg gactccatag cccaagtgtc tgggttgtgg
    19021 caatactggc aacgcatgtg acagccctgc aaaaagacaa taaagcgaat accaggccca
    19081 tctactgacc caaagctttc tgtcgaatgc accatccctg tcacttgtcc ataatcaatt
    19141 gtttcttcag acatatcgtt accttccttg aaaacgtttt atagttttat tatatcacga
    19201 cttgaaggaa aaacaagatt tttgcctatt ttttagaaag caatctgttt ttcaatttca
    19261 ttttcaatct attatcagat tattcttcaa aatcgaagcc atataaggtt gcaaaatagt
    19321 cctcagggcg ctctgcacgg cggatttgac gggctttacc ttcttcggta tagaggattt
    19381 ccgcagaacg taatttggca ttatactggt agcccattga aaatccgtgg gcacctgtat
    19441 catgaattac cagcaaatca ccgatttctg tatgaggcag ttcgcgattg actgcaaatt
    19501 tatcattgtt ttcacagagt gaaccaacca catctaccgc ttcagctggt ccatctggat
    19561 gggtcacgtt gctaatatga tggtaagctc cgtacatagc tggacgcatg aggttgactg
    19621 ctgaggcatc tacacctaga taggtacggt aggtttcctt cttatgagtg actcttgtga
    19681 ctagagcacc gtgaggtgcc agcataaaac gacccaattc ggtgaaaatc ttgacctgac
    19741 caagacctgc tgacgtaaga acttcttcat acaccttacg aactccctca ccaatcaagg
    19801 cgatatcgtt cggctcctgg tctggacgat aattaacacc aataccgcca gaaagattga
    19861 taaagtctaa cgaaatgccc aacttttcct tgatttcaac agccagttca aagagctgac
    19921 gagccaactc tggataatag agatgggtca cggtattgga cgctaggaag gagtgaagcc
    19981 caaaagtctt ggctcctttt tccttcaaga tagcaaaggc ttcaaagagc tggtccttgg
    20041 tcatgccaaa cttagcctcc ccaggattgt ccataatgtc tgtccccagt tcaaaaacgc
    20101 ctccaggatt ataacgacaa gagatgattt ctggaatgcc tgctactctc tccagatgtt
    20161 caatatcttc aaaggcatcc aagttaatgg tcgcacccaa ttcacgtgca taggcgtatt
    20221 ccttgtctgg cgtgttgttg gaagagaaca taatctcaga acccagaaag tccagtttat
    20281 ggctcatcaa aagctctaca taactagagc agtccacacc acaaccttct tcttggagaa
    20341 ttttcaaaat agctggagtt ggagtagcct taactgcaaa atattcctta aagcccttgt
    20401 tccacgaaaa agcttggttg acagctcttg ccttctcacg aatccccttc tcatcataca
    20461 agtgaaaggg agtcgggaac tcggcaacaa tcgcttctaa ctcttctcta ttgataaatg
    20521 gtgttttcat aagcttcctt ctattctgtt tgcaaagaaa ggctgggaca atcgttccaa
    20581 cctttagttc tatctcttat ttatcttcgt caaagatatt gccaacctca acatcgatgg
    20641 cttggttctt gacatcaata ttggttacct tcaagagtga cttgtagtca aactgctttt
    20701 cacgttcttc ttgggcattg tccgcaaaga ccgctacacc tgccagttct gagtcgaact
    20761 cgcgcaagag actaatcata ccgttgaccg ttccgccacc tttcaagaag tcatccacaa
    20821 tcaagacacg gctgcctgcc ttaagactac gttttgaaag gaacattttc tcgatacggt
    20881 caccacttga acctgaaaca tagttgacgc taacagttga accttcggta attttcaggt
    20941 cacggcgcac aatgacaaaa gagacattga ggacattggc aactgcattt gcaagtggca
    21001 cacccttagt tgctacggtc ataaccgcgt caattttttg gtccataaag cttttggcaa
    21061 taatacgacc aatatttttc aagatggctg gtgtgctaag caaatcagac agatagatat
    21121 aaccacctgg caagatacgg tcactttctg acaacttggt acgcaagtct tcaaccattt
    21181 ccttagcatc ctgactcgaa atagacggtg tgaagatgac acctccgcca gccccagtca
    21241 ctgtctggat atgaccgatt tcaatttcct caaaggcgcg tttgataatg acgatatctt
    21301 ctgagatgga tgatttagca gactcatact tttcagcaaa agtattgaga ctagttagtt
    21361 tataaggatt attaatcaaa tagttggaaa tgacaaccat ccgatcactt cttcttaatt
    21421 tcatttctat ttcctattcc atttttattc aaaaaatcaa aaagcaaact agaaagctgg
    21481 tcgctggtgg ttcaaaacac tgctttgaga ttgtcgatag aactgacaaa ccctgtaata
    21541 tacctgcata tatacatacg acaaggcgat actaccctag tttgaagaga ttttcgaaga
    21601 gtattcattt ttgtctttta cttattatac catattcaca taaaaaaacg aacattctta
    21661 tcctaaaaaa tgctcatttt tcttaaatta ttaatctaaa tctggtttat agaaggaacg
    21721 attatccata gcgaagattt tattggacat ctctccttta tccaccaaag ccagagctgt
    21781 tgacatcatc atcatgcttg catccagatt gtcaatcata tggataatct ctgcctccat
    21841 aatacgtgga cggactggac ttccatattc aagcaagccg tggtgactga ggatgacatg
    21901 acgaagcaaa acgacttctt ccttggtatc gtcgatgccg agttccataa ctgtcttggt
    21961 aatttcgcta tcaatgagag cgatatgtcc aagaagattg cctcgcactg tgtactctgt
    22021 ctggtctggc cccgtcaact cgatgacctt agctaagtca tgcaacataa tccccgcata
    22081 gagcaggctc ttattgagct gaggataaac ttcgctaata gcgtctgcca aacgcaccat
    22141 ggtcgccgta tgataggcca agcccgtttc aaaggcatgg tggttggtct tggcagctgg
    22201 ataggagtag aattccttat catacttggt gtagagattt cggacaatcc gttgccagac
    22261 aggattttca attttgaaaa tcatttgcga catgtagtca cgaatttcct tgacatcaac
    22321 tggtgacttg accttgaaat cagctgggtc attgggttca ccagcttgag gcaggcggag
    22381 agtaatttga ttgacttgag gggtattgtt ataaacttct cggcgtcctt tcatgtggac
    22441 aaccttacct gcggtaaagg cctcaatgtt atgaggttgg gcatcccaga gcttcccatc
    22501 aatctcgcca ctatcatctt ggaaggtaaa ggctaggtag tttttcccag ctcgagtttg
    22561 cctcaggtca gctgatttga ttaggtaaaa gccttcaaat aactcatctt ttttcatgtg
    22621 actaatcttc atattcttcc tcattttctt gaaaatggag tagatcaagc gcaggctcac
    22681 cttctgacaa ctcaatgtga cggagcgtcc gctcgatagc tatggtacga cggtttaata
    22741 attcatcaat attgccagag gcatgttgga gatgtttttg tgccttgacc agaataccac
    22801 caaacttgcc aaactcggtc ttgacactgg caagagtctt gctgatatgg tcggcactct
    22861 tttggatatt aagggtcttg aaaccaactg atagggagtt aagaagggct gatagggtac
    22921 ttggtcctgc aacaataatc tgttcttccc gtctcaaatc atcaaagaag accggattgc
    22981 ggacgatttc tgagtagaga ccttctgtcg gaacaaacaa gattccaaaa ttggttgtcc
    23041 gaggcggtgc tatgtacttg ctcttgatat ccttggcaaa gcgcttgacg cttgctagga
    23101 gtgacttacg acagcgttca atctcatcct tgtcacctgt ctcataggct tcttccaagc
    23161 ggtaataatc tgccagtgga aacttagagt caattggaag atagacgtat tcttggtcgc
    23221 cttgtccggg taacttgatg gcatactcca ctcgttcact agagttttca accgttgcgt
    23281 attctcgttc gtactgggca ggtgtcatga tgtcttcaat aatttgcccc agttgcaatt
    23341 ctcccagaat ccctcgcgtc ttggttccag agagaacctt gttaagagct ccgacatcac
    23401 gggcaactgt ctgcatttct ccaagaccac gattgacaga ctccagttgt ttagaaactg
    23461 tctcaaagga agcctgtaag cgtgtctgca aggtcttttc tagtttttcc tcgaccgtct
    23521 ggcgcatttg ttccaaacgt tgctcatttg attcctgcaa ggcttggaga cgttggtctg
    23581 tcttgtctct agtttggagg agattatctg tcatttcttg acggacttgg gtcaggcctt
    23641 ggtgcaattc aatccgcact tcttgcaaac ggtcgctgac agccacttcc aaatcttttt
    23701 ggtctaactg gctggcttgt ctggcttggt caaagcggta atccaactgg tctgacaaat
    23761 gatctgcctg atcctccaag ctcttactta agtgtttctc ctgcctatcc tgcctttgcc
    23821 aaatcagaaa gagaccagct aggttggcaa ttaataatag aataagtaaa ctttccatcc
    23881 tacctcctat ccttgctatg cagtacgacc acataaccat ctgggcaagt taccgacact
    23941 tccctatcta tatattcgtt agaagcgtac acttttttaa agaaaaaatt ttcctctgtc
    24001 aactcatact tggctccaag aatagtcagc tggctatccc gaactggcat aaaggctaga
    24061 tagtcgtagt ctgaacgagg ttctagctga ctggtccctt ctggacaata agtaatcaag
    24121 ttttgcccat cctcaatttc tatttgatgc atatagggtg ccaacttagg attgctaggc
    24181 agaaagacat tggccaacat atggtcaata cggccaccca aggcaccgaa aatagtaacc
    24241 tgagcctgag gattttgttc aaagatggtt aagagagcca attccaaatc ggtatcatct
    24301 ttttctggtc gtgcttggac aaaatgctgg gcacgttttt gaatcacctg tcgctcttct
    24361 tcggtcacag aatcaaaatc cccaactgct agagcaagag gcaagtcttc ttccaagacc
    24421 cagagcgagc ctcgatccac cccaacaaaa gcatcaaaat ctgtccgata atgaccgcgg
    24481 tctccgcctg caaaaacggc aaccctagtc cagttgtttt ctgagagttt gtactcgctc
    24541 attgacatct cccttaaaga cataggaacc tgctacaaaa acggtcgcac cagcttcttt
    24601 agcttgggca atagtttggt catcaatccc accatccact tcgatttcaa agttcaaacc
    24661 tttttcctca cgaagagcaa ccaactcacg aaccttatcc atggtttctg gcagaaaggc
    24721 ttgcccacca aaacctggat taaccgtcat gactaaaact tggtcaacta gatgaaggac
    24781 gtgcttgatg gcttcaactg atgtgccagg attgataacg actgaaggct taactccgag
    24841 tgaacgaatt ttttggaggg cgccatgaat atgaggcgtt gcttctacat ggatactgat
    24901 gatgtctgca cctgcgcgcg caaagtcttc cagatggtgt tcaggattcg ccaccatcaa
    24961 gtgacagtca aagaccatct tactatgtgg acgaagtgct tcaaccacac cggcaccaaa
    25021 actgatttgt ggcacaaaat gactgtccat gatatcgata tgggcatatt ctgccccagt
    25081 tgcttctaga cgtttgattt cacgttcaaa gttggcataa tctgctgcca gaattgacgg
    25141 agcaatcttg tattgagaca taggtttctc cttattttgg aatttttttg ctgacttttt
    25201 tatgggtttc tctacgattt tcaatttcac taaggaattg caggtaattg tcaaaacgga
    25261 aggttgcaat aacaccctct tcaacagctg gtttgacggc acaagacggc tcatgggtat
    25321 gggtacaagt acgaaactta caatctcggc tgacagtagc aatctctggg aaagcctgat
    25381 tgaggtcttc agcccttgat acttcatagt ccagagatga aaagcctggt gtgtctgcga
    25441 ttttaccccc attgaggttg aaaaaactaa cagctcgagt agtatggcgc ccacgaccca
    25501 gactgtctga gatttctcct gtttcaagat tgaggtctgg tgcgattttg ttgagaagag
    25561 ttgacttccc aacacctgtc tgccccataa agaccgtaac cttgcctgtt aacaaagaca
    25621 ggagttcctc tttactggtc acaaagtcat agccgatgtc accataggtc tgctggtaaa
    25681 aatccagttc tcccctatct tccaacaaat ccattttgga aatatagaca atgggatgga
    25741 tgcccttgtg ctccaaaaga accaagaaac gatccagcaa attgctgtta aaatcaggtt
    25801 ccttgacgga catgattact acagcttgat cgatattgac aataggcgga cgaaccagac
    25861 tgtttttccg ttcgtgaatt tttaggatat agccttctga attttcctcg gcagagaaat
    25921 ctacccagtc cccaacataa ggggtatggc cttttttacg gaaattccca cgcgcgcgtg
    25981 tttgataaac ctggccatca ctctccacat agtagaaacc tgccaaggct ttaatgattt
    26041 gtccctgcat cttagagtcc ttgcccttta agtgcgtctg ctagacaggc aaattctgcc
    26101 aagctgagag cttccccacg cacacttggt gacaagcctg cctggtccaa agccttggtc
    26161 agcttgtcct tgacctcttc agtcttacca aagtaacctg tcaagttatt ccacaaggtc
    26221 ttacggcgat gggtaaaact agccttggaa accttaaaga agaagttctc atcttccact
    26281 gctacagctg gctctggacg gcgcaccatt ttcaagatgg ctgaatccac atttggcgct
    26341 ggcacaaaga ccgtacgagg cacgataaag gcaaccttgg ctgtcatgta atactgcacg
    26401 gcgatagaca agctaccgta agccttggtg ttaggctggg ctgaaatgcg gtccgctact
    26461 tctttctgca tcatgaccac aaactcacta aaaggaatcc cactctcaat caagtgcatg
    26521 agaataggcg tcgtgatgta gtaaggcaaa ttagccacta ccttgattgg caggttagga
    26581 tttttaaaat tttggatatg ttgcgccaaa tcaaccttga gaatatcttc gttaactaca
    26641 gtcacattat caaaatcacg cagggtatct gccaaaattg gcaccaaacg gtggtcaatc
    26701 tcaaaagcca tgacttgggc tgcacgctca gccagaaact ccgtcaaggc accaatacct
    26761 ggcccgattt cgatgacatt gacctggtca tcaatttcag ccgtatccac aattttttga
    26821 aggatattgg tatccgtcag gaaattttgc ccgaaggact ttttaaaggt aaaaccgtga
    26881 cgctccagca ctgccttggt cacgctataa tctgcaattc tcatctattc tcttttctat
    26941 tatctgttac tactattgta acacattccc cttgtatttt gggaatgaaa atcataccaa
    27001 aaaactatct ttcctcatga agaaagatag tcttggaaat ctttaaaagt ggccttaaca
    27061 gttctctcga aacatgcgtt caaaaaaatc agcttcttga taacttcgat tttcgggtag
    27121 ggtcaaatcc acatcctcct ccacatcatc cactgtcagt tcaaccgtct gaggtaaatt
    27181 tttcaaacga taatgctttt gcctttgccc ttcaatacta gcaaaatcaa gcaaatagcc
    27241 atgtactcgg atttgaacca aaaggagatg attggtcata ttttccatga tgaggatatc
    27301 ttctaaacca cctctggcac taggataatc agatactctg cgaatacgga ttttttcaca
    27361 catgagcaag tttcctcata tcaatgattt catcagcctt attccagact aggggattat
    27421 gggtcgcaat gatgatcatt cgattttcat ctttcaaatc caccaagaga ttcataacct
    27481 cctctgaatt ttcaggatca agagctgctg ttggttcatc tgccaaaatc aagggtggat
    27541 ttttcaaaat agtcttagca agggcaactc gttgggcctc tcccccagat aaagtataaa
    27601 ttttttgttc taaatccaaa taccctagat taactttttc taaagccccc acttgccttt
    27661 ccaaacgttc tacttttgag attttctgac caacaaaacc caaatccaaa ttttctttga
    27721 ttgattggtt ttctaagagg ccaaaatttt gaaagagata gcccatctga tctcgaaaat
    27781 actcacgagt gggaatggtt tttaaatctt tcccctgata gagaaccctt cctccatcta
    27841 tcttttctag ctttcccaag atattcagca gcgtcgtctt tccgcttcca ctctttccga
    27901 ttaaggcata aaccttgccc ttctccagct tgagattcaa accagagaaa atcgcgcggt
    27961 cattaaattt cttttccaat ccttgaatat caatcatctt attttccttt caatactgcc
    28021 atgctaccag cttcttcttt tttgtcctgc cttactaaaa tcaagagggc gttaagcgta
    28081 aacaaagcta caactagagc gctaatcaaa ccatctcttg tcaaaatact agataggact
    28141 aggccaagca agagaactcc tccttgcgcc agtaaatact tgccatgaag ctcatagatt
    28201 gtcataccag caagacgttt aatcataagc tcccgtctga actgctcaaa atagagaaga
    28261 ttcatggaat caaataacaa gatagccgta gacagggtca aaatcgtccc aataaggaga
    28321 gagtaaaact ccacccgttt gtcatttagt accttggcaa aaaatagctg gctttttacc
    28381 aagtaagaaa ccttgtgata cagaccttgc tcttttagag ctgtgatgct gtctccatat
    28441 cgatctagtt tcaaggcact attagccgta gttccccaca acatccctgc aacaggtctt
    28501 gttccagtcg cttgcggcgt tagaactaca ataatcggat cttttaggta ctggcgtgtt
    28561 gtcttgtacc catcattata gaggaaacgt tcctgtcctg tttctgtaaa agctagcctt
    28621 acctgtggga agtagtgttt ctgactcgtc acttctacac tttcagatga aaagttttgc
    28681 aggtaatctg taaacaatcc ttggtagtag gcagactgct ctcgcaagct ctcaggcaag
    28741 atcagcccaa actctccctc agacaagttt tgcatcttgt ccataaactc tgaagaaacg
    28801 gtaatctttt cttctatcag atagcgtggt gagacataga taacattccc tgacggtgtg
    28861 tagtcactga gacgattacc atctaggtcc acttctgctc catctgagaa attgtcaaca
    28921 ttgctcataa tataaaaaga gtctgtattg gctaaccgtt cttcagtaaa tgtctgccac
    28981 tcacgattat ccttacgcgt tccttcttca tcggcaaatg cactagacca accaaaggat
    29041 agacggtaac ggtctgagta ctggctccat ttattgctag ctctctccat ttcctgcatt
    29101 tcacggtagt ggggtaggag agctgtcgca ctcgatccga ccaccaatac agctaagagt
    29161 tgccccacca tcatcaatgt catcatacgt ttgagaggga gtttcccttt caatagatcc
    29221 accagactat tttcctgtaa accaagtaga tagacgacac ttagtaaggt agaaatccct
    29281 gccaagatca atccataaag tagaagagca atgatgacca gttgcaccgt tgccataaac
    29341 aaggcacctt gataccagag aatccccaat cccaaaatac tggataccag cactgagcag
    29401 ataagctgtc tcacatcttc taacactggt ctgagagcaa ctccaaacaa gctctcacca
    29461 gctattaagc gaatccctgc ctgacgaagg gatttgatcc gataaatcag ggtcagactc
    29521 ataaaggtca gcagaaaaat agctaaactc agtagcacca taggggtggc cgtcaatagt
    29581 aagactatcg aaaatggatc ttctccattc gaaacaaagc cttgatagcc aagttctttc
    29641 aaggtggtct gtaagctcac tccatccaaa cttcctgaca caatcaagta agaccctaat
    29701 aaatcactcg tttctgcact ctccttggag gaaatggtca gaccttctgg aagctctccc
    29761 tcaccataag tggcataggt aaagagtgtt tctccagctt catttggctc aacgattcga
    29821 cgggcgatga gactattatg ctctaccgcc aagtgactca aagcctctgt caccttttcg
    29881 cgactagcta ctggttgatt tatcatcatt cctgtcacat caacagaagg atagttacca
    29941 aataaaatct cttctcgatg gtcaacggaa gttatcacca tataaagcga taccaatacc
    30001 attgaaatca aaataaataa acgtttcatc atttcctcca aaaagttact tggtcactta
    30061 gtgagaaggt gaccacagtc actgcgatgt taagaagctt attaagttct ttctgctagc
    30121 aacatcttca aatatattat atccgttttt tcaagaacta tcaaggacat caatgtcctt
    30181 aaaatctaac tatttcatat tatttttagc ttatatctaa aaaaacagtt ctaaagacga
    30241 actttagaac tgttttgata cgaggacaag gacatttttg tcactgattc actatgttta
    30301 taaatatttt ttgacatcct cttgccattc ctctgtcaat ttctttacta gaaatccatc
    30361 tccaattagc ttcgcaaatg ttttagaaga ctgataaaat gattcagcta aactaaaatc
    30421 tctttctact cttaatgctt gcttccacaa aaacataaat acaagaggtt tcttttgata
    30481 atcttgagtt ttatccataa tttcttgtaa acacgataga taatcattaa aacaatcagt
    30541 tactcctacc ttttcaagac aacacattcc tgaaataaga gtatctctaa ttataaagta
    30601 attctctatt tgagttacct tcttctgttc caaaagaaag agcattagct tttcgatttg
    30661 atttataaat ttggcaagat cttttctaat gagcatttga taaaaaaaca aacgaatcaa
    30721 caacatatca tttgttgaat aaacttcttt ttctatgatc tgagacatat gttcctcaag
    30781 tattaactct gcatattcag gccttctagt tctagaagta tccaaacacg cctgcaatac
    30841 ttcacatgct aattgttctt ctttaggaag attatcaaag tatgttttat aaatctcttc
    30901 caaacacgct tccttcttat cgtactcctc ttctttacca tagattggtt cacgtaaaat
    30961 ctggtatttc aattctaaat aagcagaagg aagagctgaa aaatccggca taaggctata
    31021 aactggaact cctagccggc gagcaatata gtctaacttg ggcaaactcg gttgcgaagc
    31081 tccactttca attcgcgaca gttgacgaac tgtcagttct tgctcatctc cacaaaaatc
    31141 tggacgacta attccttttt ctatccgaat ctctttaatt ttttgaccaa ttaacatcag
    31201 acgcctcctc ttctacctgc ttcgaaaaat actgtgaaac ttaaaaaatt gtaacggtca
    31261 catctttcct actcataaga tttcatagct tcttccactt ctgccaaagt aaccccaaac
    31321 aactctaggc gtttgaggag ttgcttgccg ttagaatagc cgattcggag agtctctccg
    31381 agatattctc tacgcttaca gctgtctgcc cctgctagaa aaccaaggcg aatcaagtcg
    31441 ctacgactaa tgtcaaactg actctcatgt tcaaattgtt ctgtcacctg agctagagcc
    31501 gttttcaggt cttcatagct ggcatgctca attcccagag aacgcccctt ggtcttggac
    31561 ttgggaacag cttcatctcg cttgagaaag gcatgctgaa ctgttggaat gaccatcatg
    31621 atcatgcgcc gaatccgttc cccattaaaa tctgggtctg taaagacaat gactccatga
    31681 cgttggtgca ggcgctgaat ccgctctata tcctgagcat tgatggcaga acctcgagtc
    31741 tcataggtct ccacatcgaa ataacgtttg agattgaccg tatcatcacg cccttcaacc
    31801 acgataactt gagaaatttt ctctttcatt acttgctgtc cagtccaaaa attcgttctg
    31861 catttgcagt cgttgctacc gccagctctt ctgtcgtcat accacgcaag tcagcgataa
    31921 agtcgaccac atagcgagta taggctgttt tattttcacg accacgcttg ggtacaggtg
    31981 ctaagtaagg cgcatctgtt tccaccaaca tcttgtccaa aggtaactct ttagctgctt
    32041 cttggaggtc agttgccttc ttaaaagtca ccactcctga gaaggaaatg gtcataccaa
    32101 gatccacaaa cttctctgcc cactcaagcg tccctgaaaa tgaatgcatg ataccaccac
    32161 gaggaccaac gccctcactc ttgataatct cataggtatc ttccagcgca tcacgggtat
    32221 ggacaacaaa aggcaaatcc aagtccttag atagctgaat ctgacggcga aaaacctgct
    32281 cctgcacctc tttgggcgct gtcatccaat ggtaatctaa gccaatttca cctaaagcca
    32341 caaccttgga atgttttaac ttatccaaca agtaagcctc aacttcctct gtataagtac
    32401 cagcttctgt aggatgccaa ccaatagtcg catagagctg ctcatactca tctaccaact
    32461 ccaaggcatg ctcaatcgtc ggtttatcaa aaccaacaat attcatctgt gtcacaccca
    32521 tctcagcagc caaggcaatt tcttctgcct cacgacctgc aaattcttct acattcaagt
    32581 gtgtatgtgt atcaaaaatc atctcttcta acctcgtttt ctatcttcta ttataccaaa
    32641 aaagaggagg ggcacctaat ttttcggttt cccctcctct cttcaataga gagctattct
    32701 gctatctttt ctatccgata ttgcccatct cctattccac agttagagac agaagagatt
    32761 ggctacattg atagaatatt cctattcagc taaagtatgt gattatcttg ggttctcact
    32821 tttctcaccc atcactagga ttgatgactt ctcaaaatcc cccttataat ctaactttaa
    32881 gtagagaata gaattttcta gctgttctat tttctacgtc tagtctttct tcctagcaaa
    32941 gcaaaaccac ttgttgccac cactagacca agactagcaa gtgctgcact tgatgctgaa
    33001 cctgtgttag gtaattgttt gccagcaggt gactggtagg taacatcttg cattgttcct
    33061 gcagttgctt gcggtgcact tgttgtctta ggagcagcat taggagccac tggtctctta
    33121 ggaactgtaa ccatggcaat ggcttgcact ccaatcgttt ctgcttcctt cacatcttcc
    33181 atagttttcg cattttcaat ctctttgaga gctgcttgtt tttctgcttc cactcttgct
    33241 aaaagttctg ctttttcttt atcagaaagc ggtgcgcctt tgatttcatc ctgcttgtcc
    33301 ttggctgctt tttcaatggc atttttagct gattcttttt cagtagctaa ttgcttagaa
    33361 gcttgtgatt gagctgagtt ttgtgaacct gtgtgagctg atccacccgc ctggctacca
    33421 ccgccttcat tcgcattagc atctgagctt ccagtattgc ctcccttatc tccacctggt
    33481 gtattttcta gcttatactc tggtgtagct tcttgagtta cagattcacc tttcgcagat
    33541 tgttgaactg tatcttttcc tagaatcgtc actactgaac catctgggaa tgtgattgtt
    33601 gctgtaccat ctccagctac attgattgtc gctccgtcta atgctgaacc atttgcttgt
    33661 aaaatagcaa ccttaacttt ttcttcatct gttaaatgag ttatatcttt tacatctact
    33721 ctttgagcag gtgctttaac agttgatttt tcagcagtca gtttagtgct atcttgtgct
    33781 tttggatctt gtgctaccaa ttgatttcct ggaattgtaa tagctgaacc atctttaaag
    33841 acgattgttg ctgtaccatc tccacctact tcaactttat agtaaaataa aataataaca
    33901 ggacaaatcg atcaggacag tcaaatcgat ttctaacaat gttttagaaa cagaggtgta
    33961 ctattctagt ttcaatctac tgtaacatcg cttccgaatc cgtttgcatc tactgaactt
    34021 ttttacaaaa ataaaaatca gtagactcga gttcctactg atttttgata gaattcgttt
    34081 ggattatgca gccaaaactt tgcgtccttt acgacgacga gctgccaata cgcgacgacc
    34141 atttttagtt gacatacggt tacggaatcc gtgtttgcgc gcacgacgaa gtttacttgg
    34201 ttgataagta cgtttcacga tgaatacctc ctcatagatt ttgtattcgt ttagccggct
    34261 ataaagtgat cagttactaa acatacttta ctattctatc tgattctttc acttttgtca
    34321 atagctctag gcaaatgttt ccagcttttt cgaatgcaag ccctatctac gatactgttt
    34381 caagaaacga gtcatctttt cttggatttg ggctaactca tcaacacgag gaaggtaaac
    34441 gatacggaag tggtctggtt cctgccagtt aaagcctcga ccatgaacca agagaacctt
    34501 ttcctgcttc aagaaatcaa ggacaaactg ctcatcatca tcgatacggt acatattgcg
    34561 gtcgattttt gggaagatat agagccccgc cttgggttta acggcagaca aacctggaat
    34621 atcttgaatg gcattataga tgaaatttct ttgctcgtag attcgtccac caggaagaag
    34681 caattcatcg actgattggt gaccccccaa ggaagtttgt acgacttgtt gggccaaaac
    34741 gttagagcaa aggcgcatat tggacagcat attgagccct tcgatatagc ccttaacatg
    34801 agtcttaggg ccagacaaga ccatccaacc cacacggaaa cctgctatgc ggtgggattt
    34861 tgacagacca ttcatgctga cacagaagac atctggtgcc aagctcgcca caggcgtatg
    34921 cacatgtccg tccattacca tgcggtcata gatttcatcc gcaaagataa tcaaatcgtt
    34981 ttgacgggca atctcaataa tctccagcaa gagttcctta ggataaaggg ctccagttgg
    35041 gttattggga ttgataagga caattgcctt ggtattggaa gtgatttttg acttgatatc
    35101 gtcaatatct gggtaccatt ccacagcttc atcacagata tagtgaacgg catttcctcc
    35161 agctaggctg acagccgccg tccatagagg atagtctggc attggcacta agacctcatc
    35221 cccattgtcc aaaagcccct gcatggacat gacaatcaac tcactgacac catttccaag
    35281 gtaaatatca tcaatatcta cgtttgggaa tttcttcagc tggcaatact gcatgatggc
    35341 cttacgggct gagaaaatcc ctttggagtc agaatagcct tcactatcac gcgcattcat
    35401 aatcaagtca tgaatgacct cgtctggcgc tgtaaagcca aattctgctg gatttcctgt
    35461 attcagacgt aaaatctttt ctccattcgc tcgcatccgc atggcttctt ccaatacagg
    35521 accacggata tcataagcaa catgctctaa cttactagac ttgttatatt ctttcatctt
    35581 gtttcctcaa ttcatcagga tagtaacatt ataccactag aaagagaatg cgacaagttt
    35641 actgaaatgt gttactagtt tcgtatagaa gaaaaacctt gctaaaggcg aggttaagaa
    35701 cgtagagata gcaggtattt tgcaaagaca catcacatac caaaagataa acctagaaaa
    35761 aagcaagcct agaaaggagt cataaagaag attaaacatg aggaaaagcc cccatatcat
    35821 caagtaatcc caacgcccac ttcgttttgc aactagaaat aagattagat ggtagagtac
    35881 atgaaaaact aaaaatccaa taaaacttgg ataaagaagc ggtaccagac tctctaattg
    35941 acagatcatg atcacttcta ccaagactga aactaggata attccataat aaaggaaatt
    36001 tgatttttga aaagagtttt tcatcattct cccttccttc acttctttcc tgctatcctt
    36061 tcttttattt tatcatatat ttatatagag tttaagccct aatattcttt tgaaaaatac
    36121 tttttttgct ttacttctat agtgaaaagg tttacaatta tagtaagaaa atttcaggag
    36181 gtttcattat ggcacaacgt taccaaaata tcatggtcgc aatcgatggt tctaaggaag
    36241 cggacttggc ttttgtcaag ggagttcatt ctgctctacg aaacgacgct aaactcacca
    36301 tcgcacatgt cattgacaca cgcgctctcc aaagcgtatc cacctttgat gctgaagttt
    36361 acgaagaact ccaagtcgac gctgaaagtc tgatgaaaga gtacgaaaaa cgtgctaaag
    36421 atgctggggt agcagatgtt catatcgtca ttgaaatggg aaatccaaag accctgctag
    36481 cacgtactat tccagatgcc gaggaagtgg acctcatcct cgttggcgca actggtctca
    36541 acgcctttga acgcctcttg gtcggctctt catctgaata catactccgc catgctaagg
    36601 tcgatttgct ggttgtgaga gaacaagaaa aaaccttata atcacaaaga aaaggagccc
    36661 ctagctcctt tttgtttacg atttatttct ctctttatgg cgttcgtaag ccttgagctg
    36721 gcgctgcagt tcctttttaa tagcaggttc tggagcatat ttttcttccc aattatctgg
    36781 ttttaagatt ttatgggtca ctggatcaaa atgagccttg ccatctggaa aaattttccc
    36841 catattggcc tgatggacaa tatcaaaaat acgttctggg tccaccccca tcaagacaaa
    36901 actgccgtag gtgaagtaaa gcgtgtcaat caaggcatcc acttgcccta tcaaatcttg
    36961 ctgagcaggt gtcttcttgg ctactttacc tgctgcctta tcaagggcct gatgaagttg
    37021 cgatacagct tgaccaaaat cttcttcaga aggactggct gatcgaacaa actccaccaa
    37081 ttcttctatt ttaaaaccag ccctatgggt tgcaccctct aaatcccaag ctcgaggttc
    37141 ttcttgggtt cgttcatcca tcatgtggtg gaaggtcttg accttattga aatgatagtc
    37201 acggctgaca aaaacttttt ctgaagacaa aacaccaaaa tgttccaagg ccttgtggat
    37261 cccatcttgt tgattgctag tggtaatgtg cttggcagct tccttgacac tgctactacc
    37321 atttcccata gcgaccgaca taccgacgcc agccagcatt tcaaggtcat tatctgagtc
    37381 accaaaagcc atgacttggt tgaggtcaaa gccatattct ttcccaactc ggcgaatgcc
    37441 ttctaattta gaatttccct gattgatgac atccgatgca aaaggattgc tacgtgtcaa
    37501 tttcaagtct tcaaaatcag ctgccgcctt ctcagattct tctggtgtca tcagcatcaa
    37561 aacttggtaa ataggttgat tcatcaggtg aagcaggtcc tcttcctttt ggggaacaac
    37621 cttgctgacc atgcgattaa aagactgact caccgtccga gttaaaacag agggaacgaa
    37681 gcgactaatt cgttgggaaa aagaacccag accaaaggac atgattttag aacccaacat
    37741 ggcatccttg gtccctaagg caatctccgt gccctctttt ttagcatagc taattagatg
    37801 gcgcaaatgt aacttggaaa tagggctcgt gaacaagact ctgtctttac taaagatata
    37861 ctggccatta taggttaccg caaaatccag atccaaatcg tccatcaatt ccttaacaaa
    37921 aaaaggtcct cgccctgtcg ctacgccaac tagtacccct tgttctttga caatcttaat
    37981 cgcgtcctta gtggatttca aaacactctt gcgattgttg accaaggttc catcgatatc
    38041 aaaaaaaaca gctttgactt ccatcctatc ccaatctccc cttttgtgat acaatgatta
    38101 taccacattt cagaaagagt gagtaaatca tgcctaagaa aatccttgtt ttacatacgg
    38161 gtggaactat ttccatgcag gccgatgctt ctggcgctgt tgtgacgagt tcagataatc
    38221 ccatgaacca tgtgtccaac ccacttgaag gaatccaagt ccacgccttg gactttttta
    38281 accttccaag tccccatatc aaacccaaac atatgctggt cctctaccag aaaattaaag
    38341 aggaagcaga taactacgat ggagtggtga tcacacacgg aaccgatact ttagaggaaa
    38401 cagcctattt ccttgatacc atggaagttc cccatatgcc tatcgttcta acaggagcca
    38461 tgcgtagctc caatgagctc ggtagtgatg gtgtttataa ttacctaagt gctttacgag
    38521 tggccagcga tgacagggct gctgacaaag gagttttggt cgttatgaac gatgaaatcc
    38581 acgctgccaa gtatgtcacc aaaacacata cgactaatgt cagcaccttc cagactccaa
    38641 cacatggccc cctcggtctc atcatgaaac aggaaatcct ctacttcaaa acagctgaac
    38701 ctcgtgttcg ctttgacctt gatcacatac aaggtttagt ccctatcatc tcggcttatg
    38761 ctggtatgac agatgagctg attgatatgc tggatttaga acacttggac ggtttgatta
    38821 tccaagcctt cggagctggt aatattccca aagaaacggc tcaaaaatta gaaagccttc
    38881 tgcaaaaagg aattccagtc gctctggtat cacgatgctt taacggtatt gccgagcctg
    38941 tttatgccta ccagggtggg ggcgtacagt tgcaaaaagc aggcgttttc tttgttaaag
    39001 aactcaacgc ccaaaaagct cgcttgaaac tcctcatcgc cctcaatgcc ggactaacag
    39061 gacaggcttt gaaaaactat atggaaggct aatactcttc gaaaatctct gcaaaccacg
    39121 tcacgtcgcc ttaccgtatg tatggttact gacttcgtca gtttcatcta caacctcaaa
    39181 aacatgtttt gagctgactt cgtcagttct atctacaacc tcaaaacagt gtgttgcgca
    39241 gcctttaacc agtcgcctag tccgctctat ggtattcatt aagtcaacat ctcttgttta
    39301 agagcacaaa atcaggaaat cttctcgatt ccctgatttt ttctatttac gttttcgtgt
    39361 tgagctacgt tctgtcaaac catgaggtaa gagaacttca cgttcttcca actcttcctt
    39421 atgcataatc ttggtcaaca tacgcatact aatggcacca agatcataaa gaggttgggc
    39481 aatcgttgtc aagtttggac gggtaaagcg tgagatttgt gaatcatcac tagtaataat
    39541 ttcaaaatct tctggcacag aaacaccctt atcagccaaa ccgttcaaga ctcctgctgc
    39601 caactcatca cctgtcacaa ctgctgcagt tgcatttgat gaaatcaaac gctctgctaa
    39661 ggcgtaacca tcatcatagc tatatttaga ttcaaatacc aaaccctcac tataagtgat
    39721 tcctgctttt ttcaaggttt ccttgtagcc aactaaacga accttaccat tgatgtcatc
    39781 cactagcgga ccgctaacga aagcaatacg ctcattttct ttagcaaggt aactcactgc
    39841 atcaattgtt gcttgcttat agtcaatatt gacacttggc aactggtgct caacatcgac
    39901 agttcctgcg agaacaatcg gagtacgtga acgcgaaaat tctgagcgaa ttttatctgt
    39961 caagtgataa cccatataga taatgccatc tacctgcttt gaaaagaggg tattgacaac
    40021 agaaacttct ttctcgttat cttcatcgct attagctagg acaatattgt acttgtacat
    40081 ttctgcaata tcatcaatcc ccttagccaa actcgaaaaa taaccattgg taatatttgg
    40141 aatcacgaca ccgacagtgg ttgtcttttt acttgcaaga ccacgcgcaa ctgcatttgg
    40201 acgataatcc aaacgatcaa ttacctctag cactttttta cgggtattct cttttacatt
    40261 tttattgcca ttgaccacac ggctgaccgt cgccatggaa acacctgctt cacgagcgac
    40321 atcataaatg gttactgtat catctgcatt cattcctttt cctgtccttt ctatctcaca
    40381 cattctttta caagtagagg tactgattga agctctatat ctacttacaa aagtgaagat
    40441 gtgaaaattt cgttttcata tttctactta ttccattcta tcactaattg taaacacttt
    40501 caagtgtttt ttgaagattg attgaaaaaa tttcatagaa aacctaggtt tagctccttg
    40561 ctaccacctt agactaaaca caaaggagga aactaagccc tcctaaagtt atagtaaaat
    40621 gaaataagaa caggataaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    40681 agtagaggtg tactattcta gtttcaatct actataggta ttgttccatt cactaccgtc
    40741 aattttagca catagccttc ataaaaatat tatatcatca taaccaacca gattcttttg
    40801 cgatattagc tgcctctgtt cgattaccag catccagttt tgaaagaata ttggtgacat
    40861 agtttcgaat agttccgttt gagaggtaaa gctgatctgc gatttcttgg ttggataagc
    40921 cccgggcgat tccctttaag acagcaatct cttgttctgt caacggattg ggacgggtca
    40981 tcaccacttc catcaattca ggcgaatact ccttgcgtcc ttcgaggacg gtgtgcaagg
    41041 tttgcatgag gtctgcaatg cttcgttcct ttaatacata agcatccact ccagccttga
    41101 ccgcacgttc aaaataccca gcacgcttga aggtcgtcac cacaaccacc tttgtttcaa
    41161 gcctttctga tcgtatccac tccaagactt caagacctgt cttaacaggc atttctacgt
    41221 caaggatggc gatatctaca gactcctttt ctaatagttg gattgcttct tgcccattct
    41281 tggcttgaag gacagactcc acatctggtt gaagcgtgag caattgacac atggcatctc
    41341 gcaacatact ttgatcttct gcgactaata ctttcatctt agtttctctc cttataaggt
    41401 agtcgaactt gcacttccgt tggatgtttc tgactgatta cacttacttc tcctgaaaat
    41461 ggaaaaacac gatctcggac tgtatggagc tcatctcctt ttagaaaagc aaagccgcag
    41521 ccatcatcac ttactgttaa aatgagttcc ttctctgtcc gttctaattt taagtaagct
    41581 ttagacgctt tggcatgttt gatgatattg gtcaccaact caagcaaaat catagaagtc
    41641 attgcctcca attcttgagt aaggctagca gtatctagtt ggttatccgt ttccacctca
    41701 attccagcaa tttctaacat ctttttcaca gtctctagtt cggatgtcaa agttctagac
    41761 ttaagatttt ccacaatggt tcgaacttca cgcatcgatt ctttgctaat ttgctgtatt
    41821 tctcttaatt ccttttccac ttgtggataa gcctgcattt gaaatagctg caaggctaga
    41881 tctgtcttga cactaagcat agcaaaggta tgtcccagac tatcatgcaa atcctgaccg
    41941 atacgattgc gctcattttc tgctagcaat agatttatct gggtattttg ctcgacctga
    42001 gcttctttca aatcctcgac aaggcgaatt cgaaccgagc ccaaagtcat caaatcgaca
    42061 aaagtaagaa ttacaagcat atagactaga aactcaactt cgattctctg aaaaatcaaa
    42121 agtcgcccca caacaaggac ttgagcaagg agaaatgtcc atacatgtaa agactttaaa
    42181 ctacgtacgc caaaatgata aattaagaga ttggaaagga aaaagaaaaa ccagatataa
    42241 ttcccagcaa caaaggcggt attcccagct acatagacca gcatgatccc ccagaaaagc
    42301 caagataggc gctggttctt agttattaaa acacccaaat acgtcactac aaatagaata
    42361 tcaaccaata aatgccaagc aggaagctcc ccaatcacta caggtaggat gggaaaaagc
    42421 ataaaaatca aactgaccca aaacatatag tgtatgcttt tcagtctttc aagcattaag
    42481 cattctcctt atgaccttga aggtaaatag tcaaaccaaa taaaactgct gaaaaaacaa
    42541 gtaaataaac tgtggctgat agattgatgc caccctcgtt taagaaggtc ttgagcaact
    42601 ccatcaattg ataggtcggg agacacttac caactgcttg catccagtct ggaaataaag
    42661 aaatgggcat ccagagtccg cctaaaacag ccaatcctag ataaagaaga ttgcccacaa
    42721 cagacatcag ctgactagtt ggtaagagag tcaaggtcaa gccaagtgct acaaaagcaa
    42781 tactccccac aatcagcaaa atcgcagctc caacccattt tactagaggc atgtctacac
    42841 ctcttacaaa atgtccaact gtaaaaacaa ccagaattga gaccaaataa tcaaccagca
    42901 tacttgttat ctttgataga taatattcta ccatatttac agggctatga cgcaatgttt
    42961 tctgccagtt gttcatctta tcggtatgta aaacagctgg aaatgagagg atagttgtcg
    43021 acatcatgga aaaggcagtc atggagatga ggtaatcacg cataaaattc gcgggttcac
    43081 ctggtgtgtc ctgatagata ccagaaaaaa ataaatagaa agccgtcggc atccctaccg
    43141 acaatagata atagattaat tgtcgtttgg tcaataaaaa ttctatctta ctaagtgcta
    43201 tccatcgttt catcttagtt atctcccttc tgcgtctctt caaagattgt attcaacaaa
    43261 ctacgattat taacttcgat ttcttgcatc ctacatcctg cttgggctaa tagttcccag
    43321 aaagcatctg cttctcgagt gactacttgt aaagaatctt gctttagggt ccagttttca
    43381 accaaatttg actgctctac gacttccttg taagctatag gaaggataaa gtgcttttct
    43441 atttcctcgc tacgcatagc tagaggcgtc gtatctcgaa tcaactctcc cttatttaag
    43501 agcaaaatgc ggtctgcagt gtgttccact tcctcaatat aatgggacga atagagaatg
    43561 gtgactcctt gcgcttttaa ctcctggaca atttcccaaa aacgttgacg agttgaggta
    43621 tccatggacg cagtaggctc atctaaaaaa acaatctttg gtcgcccaat taaggtcaag
    43681 atgaaagaaa agagacgctt ttgaccgcct gataattttt ctgccaactg ttctttttgt
    43741 tgcttgacaa actgcaatag ttgatcaatt tcctgattgc tcaaaggatt tggatagata
    43801 cgttgaaaga aagcaatcaa ctctttaact tttaatttct gaacgattac attttcttga
    43861 gggaggtaag ccctagtata gtctaactta gaactcgtca ctggtaaacc ttgaatagat
    43921 acttgaccgc ttgtgaccag tttatctcca agcaaacaat ctaagagtgt tgtctttccg
    43981 gcaccatttg gaccaattaa ggcaacacat tcaccatcgt tgatttcaaa ggagatgttc
    44041 cgcaaaattt ccttgtcttt tattttctta ctcaatttct caactttaac caccgtcatg
    44101 agactctcct ttcaaccact ccattcccat agggaaaacg acgaaaatca taaatccaaa
    44161 ccccaaagca ccatgaatga attggcgaag caaggcttga tcaaaccaat cagtaaacat
    44221 ttccactaac cataccaaga gtgacaggcc gataaagaaa tagatgatcc ctctcttcat
    44281 tcctcaaact cctttttcac atctctgact aatttcaaac cttctctaac aagccaagac
    44341 atgattccaa agccagcaaa gaccttccaa ggaaaatggt agaaatcctc atccaatccc
    44401 gaaaacatga gataggtcat aactcctgct actactaaac tcattgcaat aatcatttta
    44461 tttctcatct cttcttcccc catttcatac tacaattata gtcttttaaa atcagaggag
    44521 gcagaagctt ctgtcactag aaaatatgac aaatgtcata aaaaattctg ttcaaaacaa
    44581 gcaagataca ctatacaata aaacacaatc agaaaaatct aaggcaactt cctcaaaaga
    44641 gatatcaaac tcaattcaca ccataatgta aactaatact tatttaaaat caaaaagagt
    44701 agaaattttt atcagacaaa cacatatata gtgtattgaa tctataacag taggccttaa
    44761 atactaaaat atttctataa attaatttaa ctttcctgat agaactgttc atatcttatt
    44821 tcaattctct atattatacg ttgaacaaaa cccttctatt gctttcttaa aaatttataa
    44881 gagttataaa atctgttaaa tttcaatgtg tatacctaaa ctacggtatt tattgaaaag
    44941 actggggaca aaaagtatac gctgccaaaa tgaattactg aaaatcaaaa aagagaggac
    45001 caaactgatt ccctcttaat gtatataata tctagtttta aaaatacaca ctcacatatc
    45061 tctgt
//
LOCUS       DAVKEV010000016        45017 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVKEV010000016 DAVKEV010000000
VERSION     DAVKEV010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45017
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.016"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            168..665
                     /locus_tag="VWZ68_000853"
     CDS             168..665
                     /locus_tag="VWZ68_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEU9371912.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            665..2320
                     /gene="dnaX"
                     /locus_tag="VWZ68_000854"
     CDS             665..2320
                     /gene="dnaX"
                     /locus_tag="VWZ68_000854"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEU9371913.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTWAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATDKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2348..2542
                     /locus_tag="VWZ68_000855"
     CDS             2348..2542
                     /locus_tag="VWZ68_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEU9371914.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2692..3462
                     /gene="sufC"
                     /locus_tag="VWZ68_000856"
     CDS             2692..3462
                     /gene="sufC"
                     /locus_tag="VWZ68_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEU9371915.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3490..4752
                     /gene="sufD"
                     /locus_tag="VWZ68_000857"
     CDS             3490..4752
                     /gene="sufD"
                     /locus_tag="VWZ68_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEU9371916.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4763..5989
                     /locus_tag="VWZ68_000858"
     CDS             4763..5989
                     /locus_tag="VWZ68_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU9371917.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATAFYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVINPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5976..6416
                     /locus_tag="VWZ68_000859"
     CDS             5976..6416
                     /locus_tag="VWZ68_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEU9371918.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6470..7882
                     /gene="sufB"
                     /locus_tag="VWZ68_000860"
     CDS             6470..7882
                     /gene="sufB"
                     /locus_tag="VWZ68_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEU9371919.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8113..9354)
                     /locus_tag="VWZ68_000861"
     CDS             complement(8113..9354)
                     /locus_tag="VWZ68_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEU9371920.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKTPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9457..10566
                     /locus_tag="VWZ68_000862"
     CDS             9457..10566
                     /locus_tag="VWZ68_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU9371921.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11100..11447
                     /gene="ssrA"
                     /locus_tag="VWZ68_000863"
     tmRNA           11100..11447
                     /gene="ssrA"
                     /locus_tag="VWZ68_000863"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11620..11707)
                     /locus_tag="VWZ68_000864"
     tRNA            complement(11620..11707)
                     /locus_tag="VWZ68_000864"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11671..11673),aa:Ser,seq:gga)
     gene            11870..12610
                     /locus_tag="VWZ68_000865"
     CDS             11870..12610
                     /locus_tag="VWZ68_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9371922.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12607..13518
                     /gene="pfkB"
                     /locus_tag="VWZ68_000866"
     CDS             12607..13518
                     /gene="pfkB"
                     /locus_tag="VWZ68_000866"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEU9371923.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTVEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13515..15467
                     /locus_tag="VWZ68_000867"
     CDS             13515..15467
                     /locus_tag="VWZ68_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9371924.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSAGQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15631..17856
                     /locus_tag="VWZ68_000868"
     CDS             15631..17856
                     /locus_tag="VWZ68_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU9371925.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKTLLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(17901..18329)
                     /locus_tag="VWZ68_000869"
     CDS             complement(17901..18329)
                     /locus_tag="VWZ68_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371926.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITAGITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            18467..19609
                     /locus_tag="VWZ68_000870"
     CDS             18467..19609
                     /locus_tag="VWZ68_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU9371927.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19618..20832
                     /gene="thiI"
                     /locus_tag="VWZ68_000871"
     CDS             19618..20832
                     /gene="thiI"
                     /locus_tag="VWZ68_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEU9371928.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGRAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            20967..21790
                     /locus_tag="VWZ68_000872"
                     /pseudo
     CDS             20967..21790
                     /locus_tag="VWZ68_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            21812..22551
                     /locus_tag="VWZ68_000873"
                     /pseudo
     CDS             21812..22551
                     /locus_tag="VWZ68_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            22564..23730
                     /locus_tag="VWZ68_000874"
     CDS             22564..23730
                     /locus_tag="VWZ68_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU9371929.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     ATTFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            24238..25731
                     /locus_tag="VWZ68_000875"
     CDS             24238..25731
                     /locus_tag="VWZ68_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU9371930.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            25744..26865
                     /locus_tag="VWZ68_000876"
     CDS             25744..26865
                     /locus_tag="VWZ68_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9371931.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLRDHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     FQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLA
                     LQNEFADFVVQVDKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            26925..27161
                     /locus_tag="VWZ68_000877"
     CDS             26925..27161
                     /locus_tag="VWZ68_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEU9371932.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            27158..27571
                     /locus_tag="VWZ68_000878"
     CDS             27158..27571
                     /locus_tag="VWZ68_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEU9371933.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            27689..28654
                     /locus_tag="VWZ68_000879"
     CDS             27689..28654
                     /locus_tag="VWZ68_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU9371934.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            28678..29204
                     /locus_tag="VWZ68_000880"
                     /pseudo
     CDS             28678..29204
                     /locus_tag="VWZ68_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466610.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            29234..32584
                     /locus_tag="VWZ68_000881"
     CDS             29234..32584
                     /locus_tag="VWZ68_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU9371935.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFGENCCVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIEEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            32855..32932
                     /locus_tag="VWZ68_000882"
                     /pseudo
     CDS             32855..32932
                     /locus_tag="VWZ68_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(33170..33640)
                     /locus_tag="VWZ68_000883"
     CDS             complement(33170..33640)
                     /locus_tag="VWZ68_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU9371936.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(33657..35930)
                     /locus_tag="VWZ68_000884"
     CDS             complement(33657..35930)
                     /locus_tag="VWZ68_000884"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEU9371937.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHINKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            36277..39378
                     /locus_tag="VWZ68_000885"
     CDS             36277..39378
                     /locus_tag="VWZ68_000885"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEU9371938.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQKSEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQVDD
                     SKKKLDVTLFSDLYRQVGQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHDSDQEMSRILDQYKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNGIVMKT
                     IYR"
     gene            39460..40467
                     /gene="pfkA"
                     /locus_tag="VWZ68_000886"
     CDS             39460..40467
                     /gene="pfkA"
                     /locus_tag="VWZ68_000886"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEU9371939.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     L"
     gene            40526..42031
                     /gene="pyk"
                     /locus_tag="VWZ68_000887"
     CDS             40526..42031
                     /gene="pyk"
                     /locus_tag="VWZ68_000887"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEU9371940.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(42765..42990)
                     /locus_tag="VWZ68_000888"
                     /pseudo
     CDS             complement(42765..42990)
                     /locus_tag="VWZ68_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            43838..44710
                     /locus_tag="VWZ68_000889"
     CDS             43838..44710
                     /locus_tag="VWZ68_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEU9371941.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGIKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            44723..44887
                     /locus_tag="VWZ68_000890"
     CDS             44723..44887
                     /locus_tag="VWZ68_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371942.1"
                     /translation="MTVILGFLFLFLMTWWVISIVNSQKPLKNETFIGYVQRYDIDGN
                     GYQSLPCPQN"
     gene            complement(44856..45011)
                     /locus_tag="VWZ68_000891"
                     /pseudo
     CDS             complement(44856..45011)
                     /locus_tag="VWZ68_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT        13752 a         8015 c         9733 g        13517 t
ORIGIN      
        1 tcgcttttca ttatagatct tatgggactt tttttctaca ataaaatagg ctccataata
       61 tctatagggg ggttacccac tacaaatatt atagagccca aaatcctttg tttactaaac
      121 aagggatttt tcttttgtct ctgctccttt tttgatataa tagttctatg ttaaaatcag
      181 aaaaacaatc acgttatcaa atgttaaatg aagaattgtc cttcctattg gaaggcgaaa
      241 ccaatgtttt ggctaatctt tccaacgcca gtgctctcat aaaatcacgt tttcctaata
      301 ccgtatttgc aggcttttat ttgttcgatg gaaaggaatt ggttttaggc cccttccaag
      361 gaggtgtttc ctgcatccgt attgcactag gcaagggtgt ttgtggtgag gcagctcact
      421 ttcaggaaac tgttattgtt ggagatgtga cgacctatct caactatatt tcttgtgata
      481 gtctagctaa aagtgaaatt gtggtgccga tgatgaagaa tggtcagtta cttggagttc
      541 tggatctgga ttcttcagag attgaggatt acgatgctat ggatcgagat tatttggaac
      601 aatttgtcgc tattttgctt gaaaagacaa catgggactt tacgatgttt gaggaaaaat
      661 cttaatgtat caagcacttt atcgaaaata tagaagtcaa aacttctccc agttagttgg
      721 tcaagaagtt gtggctaaga ctcttaaaca agcggtggag caagagaaaa taagtcacgc
      781 ttatcttttt tctggtcctc gtggaacggg aaaaaccagt gttgctaaaa tctttgccaa
      841 ggctatgaac tgtcccaatc aagtgggtgg cgaaccttgc aataactgct atatttgtca
      901 agcagtgacg gacggtagtt tagaagatgt cattgaaatg gatgcagctt ctaataatgg
      961 ggtagatgaa attcgcgaaa ttcgtgataa atctacctat gcgcctagcc ttgctcgtta
     1021 taaggtttat atcatagatg aggttcacat gctgtctaca tgggctttta atgccctcct
     1081 aaagacgctg gaagaaccaa cacagaatgt agtctttatt ttggccacta ctgaattgca
     1141 caagattcct gctactattc tatcccgtgt gcaacgtttt gagtttaaat caattaagac
     1201 acaggatatt aaggaacata ttcactatat cttagaaaaa gaaaatatca gttctgaacc
     1261 agaggctgtg gaaatcattg ccagacgggc ggaaggtgga atgcgggacg ccttgtctat
     1321 tttggatcaa gccctgagtt tgacacaggg aaatgagctg acgactgcta tctctgaaga
     1381 aattactggc accattagcc tatcagcctt ggatgattat gtggcggcct tgtctcaaca
     1441 ggatgttccc aaagctttgt cttgcttgaa tcttcttttt gacaatggta agagcatgac
     1501 tcgttttgtg accgatcttt tgcactattt aagagacttg ttaattgttc aaacaggggg
     1561 agaaaatact catcatagtt cagtctttgt agaaaatttg gcacttcctc aaaaaaatct
     1621 gtttgaaatg attcgcttag caacagtgag tttagcagat attaagtcta gtttgcagcc
     1681 caagatttat gctgaaatga tgaccgtccg tttggcggaa atcaagcccg aaccagctct
     1741 atcaggagcg gttgaaaatg aaattgctac gctgagacag gaagttgccc gtctcaaaca
     1801 agagctttct aatgtaggtg cggttcctaa acaagttgca ccagctccta gtcgaccagc
     1861 tacggacaaa acagtctatc gtgtcgatcg caataaagtg caatctatct tacaagaggc
     1921 cgtcgaaaat cctgatttag cacgtcaaaa tctaattcgt ttgcagaatg cctggggaga
     1981 ggtaattgaa agtctaggtg ggccggacaa ggctctgcta gttggttctc aaccggttgc
     2041 tgccaatgaa caccatgcta ttcttgcttt tgagtctaac ttcaatgctg gtcaaactat
     2101 gaaacgagac aatctcaata ccatgtttgg taatatcctc agtcaggcgg caggtttttc
     2161 acctgagatt ttagctattt ccatggagga atggaaagaa gttcgcgcag ccttttcagc
     2221 caaagccaaa tcttctcaaa ctgaaaaaga agtagaagaa agcctgattc cagaaggatt
     2281 tgaatttttg gctgataaag tgaaggtaga ggaagactaa agaaagattt catgatacaa
     2341 taagtttatg aataaacaac aatttattat tatggcgctg tttacagctg ctgagaccta
     2401 ttttttcaat gaagcctgga tgactggccg ctatattatg gcagcctttt gggcaatttt
     2461 actctttaga aatttccgag tcagttatgt gatgggcaaa atcgttgatg tcatcgatca
     2521 gcattttaat aggaaagact agccctcagc ttccagacaa aatcaaagcc ttttaggctt
     2581 ttttttgtta tactagaaaa gtatatttat agaatttttg ctctatttct ggggaaatca
     2641 gacgtttttc tagtaagtac tgtaaaagtt ttgaaaaaga aaggaactat catgtcagta
     2701 ttagagatta aagatcttca cgttgagatt gaaggaaaag aaattttaaa aggggttaac
     2761 ctgaccctga aaacaggaga aattgccgct atcatgggac caaatggtac aggtaaatcg
     2821 actctttctg ccgctatcat gggaaatcca aactatgaag taactaaagg tgaagttttg
     2881 tttgatggcg taaacatcct tgagttggaa gtggatgagc gtgcgcgtat gggacttttc
     2941 cttgctatgc aatacccatc agaaatccct ggaattacca atgctgagtt tcttcgtgcc
     3001 gctatgaatg cgggtaaaga agatgatgag aagatttcag ttcgtgagtt tattactaag
     3061 ctagatgaaa aaatggaatt gctcaacatg aaagaagaaa tggcagagcg ttacctcaac
     3121 gaaggcttct ctggtggtga gaaaaaacgc aatgaaattc ttcaactttt gatgttggag
     3181 ccaacatttg ctcttttgga cgagattgac tcaggtcttg atattgacgc tcttaaagtt
     3241 gtgtctaaag gtgtcaatgc catgcgtggt gaaggttttg gtgctatgat catcactcac
     3301 taccaacgtc ttttgaacta tatcacacct gatgtggtac acgtgatgat ggaaggtcgt
     3361 gttgtccttt ctggtggtcc agaattggct gcgcgtttgg aacgtgaagg atacgcaaaa
     3421 ttagctgaag aacttggcta cgactacaag gaagaattgt aatttcctcg tatcttttag
     3481 gagaagtaaa tgactagaga aaatattaaa cttttttcag aaatgcacgc tgaaccaagc
     3541 tggttggctg atctccgtca aaaagctttt gacaagattg agactttgga attaccagtt
     3601 attgagcgtg tcaaattcca ccgttggaat ctgggtgatg gaacgattac agaaaatgag
     3661 ccatcagcaa atgttccaga tttcacagct ttagatcatc acttgaagtt ggtgcaagta
     3721 ggaactcaaa ctgttttcga acaaactcca gttgagttag ctgaacaggg tgttgtcttc
     3781 acagactttc actcagcttt agaagaaatt ccagagctga tcgaagaatt cttcatgtca
     3841 tctgttaagt atgatgatga caagttggcg gcttaccaca cagcttactt taacagtggt
     3901 gctgtactct atattccaga taacgtagaa atcacagagc caattgaagg aattttctac
     3961 caagatagcg atagcaatgt gccgtttaac aagcatatta tgattatcgc tggtaaaaat
     4021 tctaagatta gttatctgga gcgtttagag tcacgcggtg aaggaagtga caaagtaact
     4081 gccaatatca cagtggaagt gattgcacgt tctggtgcgc aagtcaagtt tgctgctatc
     4141 gaccgtctag gtgaaaacgt cactgcctac attagccgtc gtggtaaatt aggcaacgat
     4201 gcaagtattg actgggctat cggtgtcatg aacgaaggaa atgtcgttgc tgattttgat
     4261 agtgacttga ttggtaatgg tagccatgct gacctcaagg ttgtagctct ttcaagtggt
     4321 cgtcaggtac aagggattga tactcgtgta actaactatg gctgcaactc tatcggaaat
     4381 atcctacaac atggggttat ccttgaaaaa gcaactttga ctttcaatgg tatcggccac
     4441 atcatcaagg gtgctaaggg agcagatgcg caacaagaga gccgtgttct catgctttca
     4501 gaccaagcgc gttcagatgc taacccaatt cttttgattg atgaaaatga tgtcactgca
     4561 ggacacgcag cgtctatcgg acaagttgat ccagaagaca tgtattacct catgagtcgt
     4621 ggattggata aggcaactgc agagcgtttg gttgttcgtg gtttccttgg atctgttatc
     4681 gtggagattc cagtcaagga agttcgtgat gaaatgattg caactatcga agagaaattg
     4741 tcaaaacgct aaggggaagc ctatgttaga tgtagaagcg attcgcaagg attttccaat
     4801 tttagatcag attgtcaatg atgaacctct ggtctatctg gacaatgctg cgacgacaca
     4861 aaaaccccta gtagttctga aagctattaa cagttactat gagcaggaca atgccaatgt
     4921 tcaccgtggt gtccatacct tagcggaacg agcgacagct ttttatgaag ctgctcgtga
     4981 aaccattcgt aagtttatta atgcaggctc tacaaaggaa gttctcttta ccagaggaac
     5041 gacaaccagc cttaactggg tggcacgctt tgctgaggaa attctcactg agggagacca
     5101 ggtcttgatt tcagtaatgg aacaccattc taatatcatt ccatggcagg aagcttgtcg
     5161 aaagactgga gcagagcttg tctatgtcta tcttaaagac ggtgccttgg atatggagga
     5221 tttgcgagct aaattgactg ataaggttaa atttgtttcc ctagctcatg cctccaatgt
     5281 tcttggtgtg atcaatccga tcaaggaaat cactcaatta gcccaccaag ttggggcaat
     5341 catggtagtg gatggtgctc aatctacacc tcatatgaag attgatgtcc aggacttgga
     5401 tctggacttt ttcgcctttt cgggtcacaa gatggctggt ccgactggta tcggtgtcct
     5461 ttacggcaaa gaaaagtatc ttgagcaaat gtctccagta gaatttggcg gcgagatgat
     5521 tgattttgtc tacgagcaat ttgctagttg gaaggaattg ccttggaaat ttgaggctgg
     5581 aacgccaaat atggcaggag ctattggact tgcgactgca gttgattatt tggaaaagat
     5641 tggtatggat gccgttgaag ctcatgaaca ggaattgatt gcgtacgtct atccaaaact
     5701 gcaggcaatt gagggattga ccatttacgg ttctcaggat ttggctcaac gttcgggtgt
     5761 tattgccttt aacctaggtg atctccatcc tcacgatctt gcgacggctc tggattatga
     5821 aggagtggct gttcgtgctg gtcaccattg tgcgcaaccc ttgcttcagt atttggaagt
     5881 cccagcaaca gctcgtgcaa gtttttatat ctacaatacc aaggcagatt gcgacaaact
     5941 agtcgatgcc ctacaaaaga caaaggagtt tttcaatggc actttctaaa ctagatagcc
     6001 tttatatggc agtggtagca gaccattcga aaaatccaca tcaccaaggg aagttagaag
     6061 atgctgagca aatcagtctc aacaatccga cttgtgggga tgtcatcaac ctctctgtca
     6121 agtttgatgc agaggaccgt ttggaagata ttgcttttct aaattcagga tgcacgattt
     6181 caactgcttc tgctagtatg atgacagatg ccgttttagg aaaaaccaaa caagaaattt
     6241 tagaactggc gactattttt tctgaaatgg ttcaagggca aaaagatgag cgtcaaggcc
     6301 aacttggaga cgcggcattc ttgtcaggtg ttgccaaatt ccctcaaaga atcaagtgtg
     6361 caaccctagc ttggaatgcc cttaagaaaa caattgaaaa tcaagaaaaa cagtaagaca
     6421 agtttctttt gtcttatgaa ttattagaaa tgaagaaaga aaggatacta tggctgaaga
     6481 aagagtagaa ccaaaaccaa ttgaccttgg tgaatataaa tttggtttcc atgacgatgt
     6541 agagcctgtc ttatcgacag gaaaaggact caacgaaggt gttattcgtg aattatctgc
     6601 tgctaagggt gagcctgagt ggatgttgga gttccgtttg aagtcttatg aaaccttcaa
     6661 aaaaatgccc atgcaaactt ggggagcaga cttgtcagag attgactttg atgacttaat
     6721 ctactaccaa aaaccatctg acaaaccagc ccgttcttgg gatgatgtac ctgaaaagat
     6781 taaagaaacc tttgaacgta tcgggattcc agaagctgaa cgtgcttatt tagcaggggc
     6841 ttctgcccag tacgagtcag aagtggttta ccacaacatg aaggaagagt tccaaaaatt
     6901 aggtattatc tttacagata cagattccgc actcaaggaa tacccagact tatttaaaca
     6961 atactttgcg aagttggtac cgccgacaga taacaagttg gcagccctca actcagcagt
     7021 atggtcgggt ggaactttta tctacgtgcc aaaaggtgtc aaggtagata ttccacttca
     7081 aacttatttc cgtatcaata acgaaaatat aggtcagttc gaacgtacct tgattatcgt
     7141 tgatgaggga gcaagcgtcc actacgtaga aggatgtaca gcaccaacat attcaagcaa
     7201 tagcttacac gctgccattg tagaaatttt tgctttggac ggagcttata tgcgttatac
     7261 aactatccaa aactggtctg ataacgtcta taacttggta acaaagcgtg ctaaggctca
     7321 aaaggatgcc actgttgagt ggattgatgg aaacttgggt gccaaaacga ctatgaaata
     7381 tccatctgtt taccttgatg gagaaggagc gcgtggtacc atgctctcta tcgcctttgc
     7441 taatgcaggg caacaccaag acacgggtgc taagatgatt cacaatgctc cacataccag
     7501 ctcgtctatt gtgtctaaat ccatcgctaa aggtggagga aaggttgact accgtggaca
     7561 agtcaccttt aacaagaact ctaagaaatc tgtttcccac attgaatgtg ataccattat
     7621 catggatgac ttgtcagcat cagatactat tccatttaat gaaattcaca actcgcaagt
     7681 ggctttggaa cacgaagcca aagtatctaa gatttcagaa gagcaattgt attatctcat
     7741 gagccgtgga ttgtcagaat ctgaggcaac tgaaatgatt gtcatgggat ttgtagaacc
     7801 ctttacaaaa gaacttccaa tggaatacgc agttgagctg aaccgcttga ttagctatga
     7861 aatggaggga tcagttggat aaaatttgat tttatactct tcgaaaatct cttcaaacca
     7921 cgtcagcatc gccttaccgt atgtatggtt actgacttcg tcagtttcat ctacaacctc
     7981 aaaacagtgt tttgagcaag ctgcggctag cttcctagtt tgttctttga ttttgagtat
     8041 tagatttact caaaatcaag gattttgaag atgaacttgt atcaaaaaat cgcggtttaa
     8101 aatcgcgatt ttttataatt tctcgttaac aaagcggaca aactgattcc accaaacttt
     8161 taagaagaag gctttttcaa ttttcttgtc tgctaccatt tcgaaactag ggcgctctgt
     8221 ggtgatgtaa ccttgaccaa tcaagtcctt gtcttcataa gtcaaatggc caaccactgt
     8281 tccagcttca agtggtgctg ggattgcttt ggaatcaggt gtgaattgaa cagattggga
     8341 agattgattc ccaacacgtt cgattagata gatatcctct ggagccactg cagttactgt
     8401 atcttctttt ccatcttgta caggggtttt gctatcttga taggcatcgc cttgttgaac
     8461 gattttgcga agtgtaaatg tagaagaaat ataatccatt agggaagatg tagctgtaaa
     8521 tcgagcgtaa ggattattgt cttgatgatc tgcatttaaa acaactgtga tgactctcat
     8581 gcctttttcg acagtagtac caacaaaaga ctctccagcc ttatctgttg ttcctgtttt
     8641 tagcccatca aaaccaccac ggtaagcagg cataccttct aacatgtagt tggttgaagt
     8701 gattgtcatc ccagcaaaag tagaagaagg ttttttggtg atttctaaga cttgtgggta
     8761 ttttttgatg aggttgcgag caacgatagc gacatcataa gcactaagct tattttcctc
     8821 atctttttta gaacctgggt aaatgttatc ccctagagtt tcattgttaa gacctgtcgt
     8881 attgacaaca gtggcatcct gaattcccca ttccaagagt tttgcccgca tcatatcgac
     8941 gaaatctttt tctgagccag caattttctc agctagggca atagcggcgc tgttggcact
     9001 agataccaga gttgcttcaa gcaactcttc gacagtataa ttacgggcct ccataggaat
     9061 attactggct tcagaatttg tcgtcaattg ataaggataa tcagaaatat ctacaggagt
     9121 ggagagggta atacttccgt tttccaaagc ttcatagacc agataaacag taatcaattt
     9181 tgttatggaa gcaatttcga caggttgcgt tgcatccttc tcatagagaa ttttaccagt
     9241 atttgcctca acagcaatcg catgtttagc ggcaatggta aaatcttgag caacagcagt
     9301 agaagcaccc cctaaaagag agacagttaa caaagttaaa aatatttttt tcatagtagt
     9361 cttattctat cataaagaaa aaaaatattc ttgctttaat aattcatctg ttaagctttt
     9421 tgaaaatatg gtaaaataaa gtgagggagg taactcatgt ttcgtagaaa taaattattt
     9481 ttttggacca cagaaatttt actcttaacc atcatctttt acctatggag acagatggga
     9541 tctttgatta acccttttgt tagcgtgctt aatacaatta tgattccatt tttattaggg
     9601 ggctttcttt attatttgac aaaccctatt gttactttct taaataaagt ctgtaaactc
     9661 aatcgtttgc ttggtatttt aattaccttg tgtactttgg tctggggaat ggtcataggt
     9721 gttgtctatc tcttacctat tttgattaat cagttatcta gtttgattat atctagtcaa
     9781 actatttata gtcgagtaca agacttaatc atagacttat ctaattatcc tgcgctccag
     9841 aatttggatg tagaagctac aattcagcag ttaaacttat cctatgttga tattcttcaa
     9901 aatatcctaa atagcgtatc aaatagtgtg gggagcgtct tgtcagctct tatcagtact
     9961 gttttgattt tgattatgac tccagttttt ttggtttatt tcttattaga tggacataaa
    10021 ttcttgccca tgcttgaaag aacgattcta aagagggatc gcttgcatat tgcaggctta
    10081 ttaaagaatt taaatgcgac gattgctcgc tatattagtg gagtttcgat tgacgcaatc
    10141 attataggtt gtttggctta tattggctat agtattattg gtttaaaata tgctttagtt
    10201 tttgccattt tttctggtgt agccaattta attccttatg tggggccaag tattggtttg
    10261 attcctatga tcatcgcaaa tatattcact gatccccata gactgctgat tgcagtgatt
    10321 tatatgcttg ttgttcagca ggtagatggc aatatcttat atcctcgaat cgtaggaagt
    10381 gttatgaagg ttcatccaat cacgatttta gttttacttt tgttgtcaag caatatctat
    10441 ggtgtagttg gaatgattgt cgcagtgcca acctattcta tcttgaaaga aatttctaag
    10501 ttcttatccc gtttgtatga aaatcataaa ataatgaaag aacgagaaag agaattagct
    10561 aagtaaaagt caggagaacc ctgatttttc tttactggaa gtggccttta gattagaaga
    10621 ctgaaaataa gttaaagtct taaactaatt ttcacagcta agaatagtag aagttaatct
    10681 gataaaaatc gaaaaaacca gtggaattct gtgtcagggt aagttccact ggttttcata
    10741 gtctattaaa gttcgaatga aacctattta tagtagattg aaactagaat agtacacctc
    10801 taattctaaa acattgttag aaatcgattt gactgtcctg atctattcgt cctattctta
    10861 tttcatttta ctatattttg gtgcaataag tgaaaagtag accgaataat ataaggattg
    10921 attttatagt ttttaaactc aaatgaattg aaataaagag agtacgaaaa ttctcatctg
    10981 aaagtatttt agaataattc tcttcgtgaa tttcttcaaa acagatagct tcatcttagg
    11041 tatgtgattt ctttttgcat ttttgagtta gataaggtat aatggtttta ttgtcttttg
    11101 gggtcgttac ggattcgaca ggcattatga ggcatatttt gcgactcgtg tggcgacgta
    11161 aacgctcagt taaatataac tgcaaaaaat aacacttctt acgctctagc tgcctaaaaa
    11221 ccagcaggcg tgacccgatt tggattgctc gtgttcaatg acaggtctta ttattagcga
    11281 gatacgatta agccttgtct agcggtttga taagagattg atagactcgc agtttctaga
    11341 cttgagttat gtgtcgaggg gctgttaaaa taatacataa cctatggttg tagacaaata
    11401 tgttggcagg tgtttggacg tgggttcgac tcccaccggc tccattattc ctttgcattc
    11461 cttggtaaaa cgttgttaaa tcaacgtttt ttatttttat ctttggtatt cctttgcatt
    11521 cttttgctaa aaagggagtc acaaacagac cctattttaa aaaaaggata gaaaaaagga
    11581 tacaacattt gtcgcatcct aaaaataatc ttttttcgac ggaagacatg ggattcgaac
    11641 ccacgcacgc tattacacgc ctaccgcgtt tccaacacgg cctcttaagc ctcttgagta
    11701 atcttccaat acttactcaa atagtctacc ataaaggctc ttatcttgca ataaaaattc
    11761 tagaaataag aaaaaatgat agattttgaa agaaaatgat aaaaaatgct tgacttcgaa
    11821 agaaagtatg atagaatgaa tagtgtaaac gataacagga ggtgattcag tgttaaaaac
    11881 agaacgtaaa caactaattt tagaggagtt aaatcagcat catgtagttt ctctagaaaa
    11941 attagttagt ttgctagaaa cgtcagaatc aacggttcga agagacttgg atgagttgga
    12001 agcggaaaac aagcttcgtc gtgtgcatgg tggagcagaa ctcccccact ccttacagga
    12061 agaagaaacc attcaagaaa aatctgtcaa aaaccttcaa gaaaagaagt tgctggctca
    12121 gaaagcagcc tctctcatta aagaaaaaga tgtcatcttt atcgatgctg gaacaacaac
    12181 tgcttttttg attcatgaat tggtcaataa gaatgttaca gttgtgacca actccattca
    12241 ccatgccgct cagttggttg aaaagcagat tccaactgtc atggttggag gaaacgtcaa
    12301 gacggcgaca gatgctagta tcgggggcgt tgctcttaac cagattaacc aattgcactt
    12361 tgaccgtgcc tttatcggaa tgaatggtgt tgacgatggc tattatacga ctcctgatat
    12421 ggaggaggga gctgtgaaaa gagctatttt ggagaatgcc aagcagacct acgtcttggt
    12481 ggattcgtca aaaattggac aaacttgctt tgccaaggta gcaccactca aacgcgctat
    12541 cgttatcact agtcaagggc atgagctctt gcaggttatt aaggagaaaa cggaggtaat
    12601 agaagtatga tttatacagt cacactcaat ccatccattg actatatcgt tcgtttggac
    12661 caagtcaaag ttggtagtgt caatcgtatg gacagtgatg ataagtttgc tggtgggaaa
    12721 ggaatcaatg tcagccgtgt cttgaaacgt ttgaatatac caaatacagc gacgggattt
    12781 atcggtggct ttactggtaa atttatcaca gatactctag cagaggaaga aatcgagaca
    12841 cgttttgtcc aagtggcaga agatactcgt atcaatgtta aaatcaaagc agaccaagaa
    12901 acagaaatca acggaacggg tccaactgtt gaaccggttc agctagaaga attgaaagct
    12961 attttatcta gtctgacagt agaagataca gttgtctttg caggttcaag tgctaaaaat
    13021 ctaggcaatg ttatctataa ggatttgatt tccttgacgc gccagactgg tgcgcaagtg
    13081 gtctgtgact ttgaaggaca gaccttaatt gatagtttgg actaccagcc tcttcttgta
    13141 aaaccaaaca atcatgaact tggagcgatt tttggggtta aactcgaaag tttagatgaa
    13201 attgagaaat acgctcgtga gttactggct aagggtgctc aaaatgttat tatctctatg
    13261 gctggtgatg gcgcccttct tgtcacatct gagggagctt acttcgctaa accaatcaaa
    13321 ggaacagtca aaaattcagt tggagctggt gattctatgg ttgctggatt cacaggtgaa
    13381 tttgtcaaat caaaagacgc agtagaagcc ttcaaatggg gagtggcttg cggaacggca
    13441 actaccttct cagatgactt ggcaacggcg gaatttatta aagaaacata tggaaaagtt
    13501 gaggtagaaa aaagatgaaa attcaagacc tattgagaaa agatgtcatg ttgctagatt
    13561 tgcaggcaac tgaaaaaaca gctgtcatcg acgagatgat taaaaatttg acagagcacg
    13621 gttatgtaac agattttgaa acatttaaag aaggaatttt ggcgcgtgaa gctttgactt
    13681 ctactggttt gggtgatgga atcgcaatgc ctcacagcaa aaacgctgct gtcaaagaag
    13741 cgacagttct atttgctaag tcaaacaagg gtgttgacta cgagagcttg gatggacaag
    13801 caactgacct cttcttcatg attgcagctc cagaaggtgc caatgatact cacttggcag
    13861 ccttggcaga attgtctcaa tacttgatga aagacggttt tgcagacaaa cttcgtcaag
    13921 caacatctgc aggccaagtt atcgaacttt ttgaccaagc ttcagaaaaa actgaggaac
    13981 ttgttcaagc acctgctaat gactctggtg actttatcgt agctgttaca gcttgtacaa
    14041 caggtattgc ccacacttac atggcccaag aagcccttca aaaagtagct gctgaaatgg
    14101 gggttggtat caaggtcgaa accaacggtg ctagcggtgt tggaaatcaa ctaactgcag
    14161 aagatatccg taaggctaaa gctattatca ttgcagcaga caaggccgtt gaaatggatc
    14221 gatttgatgg aaaaccattg atcaatcgtc cagttgctga cggtatccgt aagacagaag
    14281 agctaattaa cttggctctt tcaggagata ctgaagtcta ccgtgccgct aatggtgcca
    14341 aagctgcaac agcctctaac gaaaaacaaa gccttggtgg tgccttgtac aaacacttga
    14401 tgagtggtgt atctcaaatg ttaccattcg ttatcggtgg tggtatcatg attgcccttg
    14461 ccttcttgat tgacggtgct ttgggtgttc caaatgaaaa ccttggcaat cttggttctt
    14521 accatgagtt agcttctatg tttatgaaaa ttggtggagc tgcctttggt ttgatgcttc
    14581 cagtctttgc gggttatgtt gcctactcta ttgctgaaaa accgggtttg gtagcaggtt
    14641 tcgtggctgg tgctattgcc aaagaaggtt ttgcctttgg taaaattcct tatgccgcag
    14701 gtggtgaagc aacttcaact cttgcaggtg tctcatctgg tttcctaggt gcccttgttg
    14761 gtggatttat cgcaggtgcc ttggttcttg ccatcaagaa atacgttaaa gttcctcgtt
    14821 cactcgaagg tgctaaatca atccttctat tgccacttct tggaacaatc ttgacaggat
    14881 ttgttatgct agctgtgaat atcccaatgg ctgcaatcaa cactgctatg aatgacttcc
    14941 taggcggtct tggaggaggt tcagctgtcc ttcttggtat cgtccttggt ggaatgatgg
    15001 ctgttgacat gggtggacca gttaataaag cagcttatgt ctttggtaca ggtacgcttg
    15061 cagcaactgt ttcttcaggt ggttctgtag ccatggcagc agttatggct ggaggaatgg
    15121 tgccaccact tgcaatcttt gtcgcaactc ttcttttcaa agataaattt actaaggaag
    15181 aacgtaactc tggtttgaca aacatcatca tgggcttgtc atttatcact gagggagcga
    15241 ttccatttgg tgccgctgac ccagctcgtg cgattccaag cttcatcctt ggttcagcag
    15301 tagcaggtgg actcgttggt cttactggta tcaaactcat ggcgccacac ggaggaatct
    15361 tcgttatcgc ccttacttca aatgctctcc tttacctcgt ttctgtcttg gtaggagcaa
    15421 tcgtaagtgg tgtggtttat ggttacctac gcaaaccaca agcataaaaa atagaaaaat
    15481 gaaaagattg gaccgtttgg tgcagtcttt ttctcttccc gaaatgcctg tgaaatatgg
    15541 tataatagaa gaatggcaaa caagaataca agtacaacaa gacggagacc gtctaaagca
    15601 gaactggaaa gaaaagaagc gattcaacga atgttgattt cgttaggaat tgcgatttta
    15661 ttgattttcg cagccttcaa attaggggct gcaggtataa ccctttataa tttaattcgc
    15721 ttgctagtgg gtagcctagc ttatctggcg atattcggcc tattaatcta tctcttcttt
    15781 ttcaagtgga tacgaaaaca ggaaggactc ttatctggct ttttcaccat atttgctggc
    15841 ttactcttga tttttgaggc ctacttggtt tggaaatatg gtttggacaa gtccgttcta
    15901 aaagggacca tggctcaggt tgtgacagat ctgactggtt ttcgaacgac tagctttgct
    15961 ggagggggct tgatcggggt cgctctttat attccaacag cctttctctt ttcaaatatc
    16021 ggaacttact ttattggttc tatcttgatt ttagtgggtt ctctcctagt cagcccttgg
    16081 tctgtttacg atattgctga atttttcagt agaggctttg ccaaatggtg ggaagggcac
    16141 gagcgtcgaa aagaggaacg ctttgtcaaa caagaagaaa aagctcgcca aaaggctgag
    16201 aaagaggcta gattagaaca agaagagact gaaaaaacct tactcgattt gcctcctgtt
    16261 gatatggaaa cgggtgaaat tctgacagag gaagctgttc aaaatcttcc acctattcca
    16321 gaagaaaagt gggtggaacc agaaatcatc ctgcctcaag ctgaacttaa attccctgaa
    16381 caggaagatg actcagatga cgaagatgtt caggtcgatt tttcagccaa agaagccctt
    16441 gaatacaaac ttccaagctt acaactcttt gcaccagata aaccaaaaga tcaatctaaa
    16501 gagaagaaaa ttgtcagaga aaatatcaaa atcttagaag caacctttgc tagctttggt
    16561 attaaggtaa cagttgaacg ggccgaaatt gggccatcag tgaccaagta tgaagtcaag
    16621 ccggctgttg gtgtaagggt caaccgcatt tccaatctat cagatgacct cgctctagcc
    16681 ttggctgcca aagatgtccg gattgaagca ccaatccctg ggaaatccct aatcggaatt
    16741 gaagtgccca actccgatat tgccactgta tctttccgag aactatggga acaatcgcaa
    16801 acgaaagcag aaaatttctt ggaaattcct ttagggaagg ctgttaatgg aaccgcaaga
    16861 gcttttgacc tttctaaaat gccccacttg ctagttgcag gttcaacggg ttcagggaag
    16921 tcagtagcag ttaacggcat tattgctagc attctcatga aggcgagacc agatcaagtt
    16981 aaatttatga tggtcgatcc caagatggtt gagttatctg tttacaatga tattccccac
    17041 ctcttgattc cagtcgtgac caatccacgt aaagccagca aggctctgca aaaggttgtg
    17101 gatgaaatgg aaaaccgtta tgaactcttt gccaaggtgg gagttcggaa tattgcaggt
    17161 tttaatgcca aggtagaaga gttcaattcc cagtctgagt acaagcaaat tccgctacca
    17221 ttcattgtcg tgattgtgga tgagttggct gacctcatga tggtggccag caaggaagtg
    17281 gaagatgcta tcatccgtct tgggcagaag gcgcgtgctg caggtatcca catgattctt
    17341 gcaactcagc gtccatctgt tgatgtcatc tctggtttga ttaaggccaa tgttccatct
    17401 cgtgtagcat ttgcggtttc atcaggaaca gactcccgta cgattttgga tgaaaatgga
    17461 gcagaaaaac ttcttggtcg aggagacatg ctctttaaac cgattgatga aaatcatcca
    17521 gttcgtctcc aaggctcctt tatctcggat gacgatgttg agcgcattgt gaacttcatc
    17581 aaggctcagg cagatgcaga ctacgatgag agttttgatc caggtgaggt ttctgaaaat
    17641 gaaggagaat tttcggatgg agatgctggt ggtgatccgc tttttgaaga agctaagtct
    17701 ttggttatcg aaacacagaa agccagtgcg tctatgattc agcgtcgttt atcagttgga
    17761 tttaaccgtg cgacccgtct catggaagaa ctggagatag caggtgtcat cggtccagct
    17821 gaaggtacca aacctcgaaa agtgttacaa caataaaaaa atagcttctt tccgagtttg
    17881 gagggaagct attttagtgg ctattgattg cttttatttt ctgaagttgg cgcattggac
    17941 tgtttttcgt tttcagtagc aggtttactt gaagcaggag tagaagagtc ctgagttgct
    18001 gttttctgat cttctttttt ctcttccttg acgctagatt ttggtgtttc ctcttgctgt
    18061 gttttttctt gactagtgtt agtctcttta gttggactgg tgttttcctt aggggattcc
    18121 ttttggattt ctttgacaat ggttgtcgtc tggcttgtcg taggttcttt tttaatattt
    18181 ttgttattat ccaaggcgtt catgatcgtg atacccgcgg taatcaagcc aaggatacta
    18241 gcgattgtag caacggtttt ttgaaagact gtaaagcctt ttttgatgtg ttctgttttt
    18301 ggttttgaag ttctacgata gttagacata cattctctcc tttgattatg atttattata
    18361 ctctgtttct ttaaaaaaat cttaaaaaaa gagaaattgc cctttcttgt cgcaggctcc
    18421 gtttcatgat acaatagaag gagtgatttt agaaagcgtg agaaacatga tttactttga
    18481 taattcggcg acgaccaggc cctatccaga agcccttgaa acctatatgc aggtggcttc
    18541 aaaaatttta ggaaatccat ctagtctcca tcgtttggga gaccaggcaa cacgaatttt
    18601 agatgcttcc cgtcaacaga ttgcagattt aatcggtaag aaaagtgatg aaatcttctt
    18661 tacatctggt gggacagaag gggataactg gatcatcaag ggagtagcat ttgaaaaagc
    18721 ccagtttggc aagcacatca tcgtatcagc cattgaacat ccagcagtta aggaatcagc
    18781 cctctggttg aaagctcaag gttttgaagt ggattttgct ccagttgata acaaaggatt
    18841 tgtggatgtt gaggcgctag aagatttgat aagacctgat acgaccctcg tttccatcat
    18901 ggcagttaac aatgaaattg gctctgttca gcccattgag gctatttcaa aactattggc
    18961 agacaagcca actatttcct tccacgttga tgcggttcag gcgcttgcca agattccgac
    19021 tgaaaagtat ctgacagaac gagtggattt cgcgactttc tctggtcaca agttccacgg
    19081 aatccgtggt gttggtttta tctatatcaa gtctggcaag aagattacgc ctcttttaac
    19141 aggtggtggt caggaacgtg attaccgttc gacaactgaa aatgtggcag gaattgcagc
    19201 gaccgctaag gctctccgtt tatctatgga aaagctagat atctttagga gcaagactgg
    19261 gcagatgaag gcagtgattc gtcaagcact tctggactat ccggatatat ttgtcttttc
    19321 agatgaggaa gacttcgccc ctcatattct gacttttgga atcaagggtg ttcgtggtga
    19381 ggtcattgtt cacgcctttg aagactatga tattttcatc tcaacgacct cggcttgttc
    19441 gtccaaggct gggaaaccag ccggaaccct gattgctatg ggagtggaca aggataaggc
    19501 tcagtcagct gtgcgtctta gtctagacct tgaaaatgat atgagtcagg tcgagcagtt
    19561 cttgaccaag ctaaaattaa tttacaatca aactagaaaa gtaagatagg agcattcatg
    19621 cagtattcag aaattatgat tcgctacggt gagctgtcaa ccaagggcaa aaatcgtatg
    19681 cgtttcatca ataaacttcg caataatatt tcagacgttt tgtctatcta tccccaagtt
    19741 aaggtaacag cagatcgcga ccgtgcccac gcttacctca atggagcaga ttacacagca
    19801 gtagcagaat cgctcaaaca agtatttgga attcaaaact tttcccctgt ttataaggtt
    19861 gaaaaatctg tagaagttct gaagtctgct gtccaagaga ttatgcagga catctacaag
    19921 gaaggcatga cctttaaaat ctctagcaag cgtagcgacc acacctttga attggacagt
    19981 cgtgaactca accaaacgct tggaagggct gtattcgaag ccattccaaa cgtacaagct
    20041 caaatgaaaa gtcctgacat caatcttcag gtggagatac gtgaagaagc agcctatctt
    20101 tcttatgaaa ccgttcgagg ggcaggtgga ttaccagtgg gaacttctgg taagggcatg
    20161 ctcatgttgt cagggggaat cgattcccct gtagctggct atctagcgct taaacgaggg
    20221 gtagatatag aggcagttca ctttgccagc ccaccttaca cgagtcctgg tgctcttaaa
    20281 aaagcccaag atttgacccg taaattaacc aaatttgggg gaaatatcca gtttatcgaa
    20341 gttcctttta cagagattca agaggaaatc aaagccaaag cgccagaagc ctaccttatg
    20401 accttgacgc gtcgttttat gatgcgtatt actgaccgta ttcgtgaggt acgaaatggt
    20461 ttagttatca tcaatgggga aagtctaggt caagtagcca gccaaaccct tgaaagtatg
    20521 aaggctatca atgctgttac caacactccc atcattcgtc ctgtggttac catggacaag
    20581 ttggaaatca ttgacatcgc ccaggaaatc gatacctttg acatttcaat ccaaccgttt
    20641 gaagactgtt gtaccatttt tgcaccagat cgtccaaaaa caaatcctaa aattaagaat
    20701 gcggagcagt acgaagcgcg tatggatgtt gaaggcttgg ttgagcgagc agtggctgga
    20761 atcatgatta ctgaaatcac acctcaagcc gaaaaagatg aagttgatga cttgattgac
    20821 aatctgctct aattcagaaa atccaaaaga atagcgaaaa tcagtaaaaa aagttagttt
    20881 tttctctaaa aacaggtaaa aaactaactt tttttatttt tatgatataa tgatataaaa
    20941 ttttgaatat agagagtttt ctggcaatga atcaatccta cttttatcta aaaatgaaag
    21001 aacacaaact caaggttcct tatacaggta aggagcgccg tgtacgtatt cttcttccta
    21061 aagattatga gaaagataca gaccgttcct atcctgttgt atactttcat gacgggcaaa
    21121 atgtttttaa tagcaaagag tctttcattg gacattcatg gaagattatc ccagctatca
    21181 aacgaaatcc ggatatcagt cgcatgattg tcgttgctat tgacaatgat ggtatggggc
    21241 ggatgaatga gtatgcggct tggaagttcc aagaatctcc tatcccagag cagcagtttg
    21301 gtggtaaggg tgtggagtat gctgagtttg tcatggaggt ggtcaagcct tttatcgatg
    21361 agacctatcg tacaaaagca gactgccagc atacggctat gattggttcc tcactaggag
    21421 gcaatatacc cagtttatcg gtttggaata ccaagaccaa attggttgct tgggcgtttt
    21481 ttcatctgca aactggctcc accaagaagc ctttaaccgc tatatcgagt gccagaaact
    21541 atcgcctgac cagcgcatct tcatctatgt aggaacagaa gaagcagatg atacagacaa
    21601 gaccttgatg gatggcaata tcaaacaagc ctatatcgac tcgtcgcttt gctattacca
    21661 tgatttgata gcagggggag tacatctgga taatcttgtg ctaaaagttc agtctggtgc
    21721 catccatagt gaaatccctt ggtcagaaaa tctaccagat tgtctgagat tttttgcaga
    21781 aaaatggtaa gttaagaaag gaaaaaacga aatgcatatt gaacatctta gccactggag
    21841 tggtcatctt aaccgtgaaa tgtaccttaa ccgttatgga catggtggga ttccagttgt
    21901 ggtctttgct tcatcaggtg gtagtcacaa cgaatactat gattttggca tgattgatgc
    21961 ctgtgcttcc tttatcgagg aaggccttgt ccagttcttt accctatcta gtttggatag
    22021 tgagagctgg ttggttactt ggaaaaatgc tcatgaccaa gcggaaatgc accgtgccta
    22081 cgaatgttat gtgattgagg aggccattct tttatcaagc acaagacagg ttggtttgat
    22141 ggcatgatga cgacaggttg ctctatggga gcctatcatg cactcaattt cttcctccag
    22201 catccagatg tctttaccaa agtgattgct ctcagtggtg tttacgacgc acgtttcttt
    22261 gtcggtgatt actacaacga tgatgctatt taccaaaact cgccagtaga ttatatttgg
    22321 aaccaaaacg acggctggtt tattgaccgt taccgtcagg cagagattgt gctgtgtacg
    22381 gggcttggag cctgggaaca agatggtttg ccatcctttt acaagctcaa agaagccttt
    22441 gacaagaaac aaattccagc ctggtttgct gaatggggac atgatgtcgc ccatgactgg
    22501 gaatggtggc gtaaacaaat gccttatttc ctcggtaatc tctatttata aaaggagtta
    22561 cctatgaatt accttgttat ttctccctac tatccacaaa actttcaaca gtttaccatc
    22621 gaactagcta ataaaggcat cacagtcttg ggaattggtc aagagtctta cgagcaattg
    22681 gatgagccct tgcgcaatag cttgaccgag tattttcgtg ttgataatct tgagaacata
    22741 gatgaagtca aacgtgcagt tgcttttctc ttttataaac atggtccaat tgaccgcatc
    22801 gagtctcaca atgaatactg gcttgagcta gacgcaacac tcagagaaca attcaatgtt
    22861 tttggtgcca aaccagagga tctcaaaaag acgaaatata agtctgaaat gaagaaactt
    22921 ttcaaaaaag caggtgttcc tgtggtacct ggagctgtta tcaagacgga agcagatgtt
    22981 gatcaagcag tgaaagaaat cggtcttcca atgattgcca aacctgataa tggagtggga
    23041 gcagccacaa cctttaaact tgagacagaa gacgatatca atcacttcaa gcaagaatgg
    23101 gaccattcaa ccctttattt ctttgaaaaa tttgtcactt ccagcgaaat ctgtaccttt
    23161 gacgggctcg tggacaagga tggaaagatt gtcttctcaa caacctttga ctacgcctat
    23221 acaccgcttg acctcatgat ttataagatg gacaattctt attatgtgct caaggatatg
    23281 gatcctaaac tgcgcaagta tggggaagca attgtcaaag aatttggtat gaaagaacgg
    23341 tttttccata ttgagttctt ccgtgagggg gacgattata ttaccatcga gtacaataac
    23401 cgccctgcag gtggttttac cattgatgtt tataactttg ctcattcctt ggacctctat
    23461 cgtggctatg cagctattgt cgcaggagag gagttcccgg cgtcagactt tgaaactcag
    23521 tattgtttgg ctacttctcg ccgtgcaaat gctcactatg tttattcaga agaggatttg
    23581 cttgccaaat atagccagca gttcaaagtt aaaaaagtca tgccagctgc cttcgcggaa
    23641 cttcaaggag attacctgta tatgctgacc actccgagtc gacaagaaat ggagcagatg
    23701 attgcagatt tcggacaacg tcaagaataa gaactatcgg attaaggaaa ttaactccct
    23761 taatcctttt gttttgtctg ataaaaaata agagcatccc aacaaggtag ctatcataaa
    23821 acttgttcga taactatttg aagcaggatt aggtggtcag aaattgaatt ttaatatttc
    23881 aattgagtca tagtattgtg tttgcgtatc cttaaatcag ctaaaaggat ccatgacgac
    23941 acctatacga tatagttttc aagataccaa acaagtctat taatactcaa tgaaaatcaa
    24001 agagcaaact aggaagctag ccgcaggttt ctcaaaacac tgttttgagg ttgtggatag
    24061 aactgacaga gtcagtatca tatacctacg gcaaggtgaa gctgacgtgg tttgaagaga
    24121 ttttcgaaga gtataaaata ttcaggtgac gcatagatat agttaattga agctttgttt
    24181 gaaatctgat aaaataatga tattactaag ttttaaaaac taaagaaaag ggaagatatg
    24241 attacaggcg aattaaaaaa taaaatcgat cagctgtggg aaattctttg gacagaagga
    24301 aacgcaaatc ctttaacaaa tattgaacag ttgacttatc tcttatttat gaaagatttg
    24361 gatagtgtcg agcttggacg tgaaagtgat gctgaatttc tagggattcc ttatgaggga
    24421 gtttttccaa aagataaacc tgaataccgt tggtcaactt ttaaaaatat aggagatgct
    24481 caggaagttt atcgtttaat gactcaggag atttttccgt ttattaaaaa tctcaagggg
    24541 gatacagatg atacagcctt ttcacgatat atgcgagaag ctatttttca aataaataaa
    24601 cctgctacgc ttcaaaaggc aatttctatc ttagatgttt ttccaactag gggattagat
    24661 gtagattttg ataatgacaa acaaagtatt actgatatcg gagatatcta tgaatatctg
    24721 ttatcaaaat tgtcgaccgc aggtaaaaat ggacagttcc gtacacctcg tcacatcatc
    24781 gatatgatgg ttgagttgat gcaaccgact atcaaagata tcatctcaga tcccgctatg
    24841 ggttctgctg gcttcttagt atctgctagc cgttacttaa agcgtaagaa agatgaatgg
    24901 gaaaccaata cagataatat caatcatttt cataatcaga tgtttcatgg aaatgatacg
    24961 gatacgacta tgttgagact tggggcgatg aacatgatgc tacatggagt agaaaatcca
    25021 caaatcagtt accttgactc gctgtctcaa gataatgaag aagccgataa atatactttg
    25081 gttttagcaa atcctccttt taagggctca cttgactaca attcaacctc taatgacctt
    25141 cttgcaaccg taaaaaccaa aaaaacagaa ttactctttc tttctctttt cttgcgaact
    25201 ttaaaaccag gtggacgagc agcagttatc gtacctgatg gtgtcctttt tggttcgtct
    25261 aaagctcata aaggaattcg tcaggaaatt gtagagaatc ataagcttga tgctgtaatc
    25321 tcaatgccta gtggtgtgtt caagccttat gctggagttt caactgctat tctcatcttt
    25381 acaaaaactg gtaatggtgg tactgacaaa gtctggtttt acgatatgaa agcggatggt
    25441 ttaagtttgg atgataagcg acaaccgatt agcgacaatg atattccaga tattatcgaa
    25501 cgctttcatc atcttgaaaa agaagcagaa cgtcagagaa cggatcaatc tttctttgtt
    25561 ccagttgctg agataaagga aaatgattat gatttgtcta tcaataaata taaagagatt
    25621 gagtatgaaa aagttgagta tgaaccaaca gaggtcatct taaagaaaat caatgattta
    25681 gaaaaagaaa ttcaagctgg cttggctgaa ttagaaaaat tactcaagta gggaggtggc
    25741 tgtatgaaaa aagtgaagtt gggggaagtc ttatctctaa aaaaaggaaa gaaagccact
    25801 gtacttgctg aacaaacaac tctaagccaa cgttatattc aaatagatga tttaagaaat
    25861 aataataatt taaaattcac tgaaagttta aatatgactg aagcactccc agatgatatt
    25921 ctaatagcat gggatggtgc taatgcagga acagttggct atgggttatc gggagctgtt
    25981 ggtagtacaa ttacggtctt aaaaaagaat gagcgataca aagaaaaaat tatatcagat
    26041 tacttgggag tctttttgga aagtaaatcg cagtatttac gagatcattc aacaggtgca
    26101 actattcctc atttaaacaa gaatatatta cttgatttac aattagaatt gctaggtatc
    26161 gaagaacaag agaacattat ctgtattctt aatacgatta aaaggcttat tactaaaaga
    26221 aaatttcagt tagatgaact aaacttgctc gtcaaatccc gatttaacga gatgtttggg
    26281 gaaaataaaa tatttgaaag cattgataac ttatttgata ttatagatgg tgataggggc
    26341 aaaaattatc ctaaatcaga tgagttgttt agtgaggagt actgtttatt tttaaataca
    26401 aagaatgtta ctaaaaacgg attttcattc gatacaaagc aatttatcac taaaacaaag
    26461 gataaattac ttcgaaaagg caaacttgag cgttatgata tagtcttgac aacaagaggt
    26521 actgttggaa atgtagcgta ctacgatgaa ttaataaaat ataaacattt acgtataaat
    26581 tcaggtatgg taatattacg tcccaagaca ccaaatctaa atcagaaatt tattatccat
    26641 gttttaagga ataataatta tagtcgagtg atatcaggaa gtgctcagcc tcagttacca
    26701 attacaaaat taaaaaaaat acttctcccc ctccccccac tagccctcca aaatgagttc
    26761 gcagactttg tagtccaggt cgacaaatca caattggcaa tccaaaaatc tctggaagaa
    26821 cttgaaactt tgaagaaatc tctgatgcag gagtattttg gctgatattc tgccattgta
    26881 attacggtaa tgatttgtta taatacttca aaggaggaaa tcagatggta gtaaaaacaa
    26941 gaaaacaagg aaattcaatc accattacga ttccaagtga atttaatatt ccaagtggtg
    27001 ttaaatacga agcgaaattg ttaccaagtg gtgagattat ctttactcct gaagaattgg
    27061 ggcagcaggt ttcttatgta tctgatgatg cctttgactt aaatttagat aaaatatttg
    27121 acgaatacga cgatgttttc aaagctttgg tggaaaaatg acaatctatc tgacagaaaa
    27181 gcaaattgaa aaaataaatg ctttagcaat tcaacggtat tctccaaatg agaaaattca
    27241 aacagttagt tcttctgcct taaatatgat tgtgaactta ccagaacaat ttgtctttgg
    27301 gaagtctctt tatccaacaa tttttgataa agcaacgata ctatttgtcc aattgataaa
    27361 gaagcatgtt tttgctaatg ctaataaaag aactgctttc ttcgttttgg tcaaattttt
    27421 acaattaaac ggctatcgtt tttctgtaac ggtagaagaa gcagtaaaaa tgtgtgtaac
    27481 catcgcagta gaagctttaa ctgatgaaaa aatgacaagc tactccaaat gggtttctga
    27541 acattctgtt agagaaaagg tcaaaaagta acctagtatg ctggatttga atgagcacaa
    27601 gaaaataaat gaacagacaa tattagaatt ctgtaatgca gaaactgata ttgtctcttt
    27661 ttattgatga ataagaaagt gagaaattat ggaatcaaaa gttacaatta tcatgcaaga
    27721 aatgttacct cttttaaata atgaacaatt actagcgttg agagagagtt tagaacatca
    27781 tctagtagac ggaaaaaagc agcagaagta ttcgaataat aacctgttgc aactatttat
    27841 taccgccaag caggtagagg gctgtagctc aaaaacaatt cgttattacc agaggacgat
    27901 tgaaaacttg tttaatgcta ttaaagagtc tgtgacacaa ctcacaacag atgatttaag
    27961 gagttattta gcaaattacc agtctgaaaa ggattgtagt aaggcaaatt tagacaatat
    28021 taggcgtata ttgtcttctt tttttgcttg gcttgagcaa gaggaatata tcattaaaaa
    28081 tcccattcga cggataaaga aaattaagac tgagcaaaat gtgaaggaaa cttatactga
    28141 tgaacatttg gaaattatgc gtgataactg tgaaaatttg agagatttgg caataataga
    28201 cctactagca tcgacaggta tgcgtgtagg ggagcttgta cagttgaatc gttcagatat
    28261 tgattttgaa aacagagagt gtgttgtctt tggtaaagga aagaaggaga gaccagtata
    28321 ttttgacgct cggacgaaaa ttcatttaag aaattatctt aacgacagaa aagatagtca
    28381 ccctgctctt tttgtaacgc tagttggaaa agcccagaga cttggaattg ctggtgtaga
    28441 gattcgctta agaaagttag gagacaaact cggcatacaa aaggttcacc cacataagtt
    28501 cagaagaact ttagcgacta aggcaattga taaaggtatg cctatcgaac aagtccaaaa
    28561 actgctaggt catagcaaga ttgacacaac cttggcctat gccatggtca atcaaaataa
    28621 tgtcaagcat tcacaccaaa aattcatctc ttaaaagcaa attcccgatt taacgagatg
    28681 tttggggatc ctttaaataa taacaagaaa tttgcagtaa aaacgggaca acagtgtttt
    28741 aaattttcaa gtggaaaatt tcttgataaa catgatagag tttttgaagg ttatcctgcc
    28801 tatggtggaa atggcattgc ttggaaaagt cgaaaatatt taattgataa tcctactatc
    28861 atcattggtc gtgtaggtgc atattgtggt aatgtaagaa ctacccacgg taaggtatgg
    28921 ataagtgaca atgctatata tataaaagaa tttaagaatt ccgatttcaa tcttgtattt
    28981 ttattagaat taatgaaagt aattgatttt agtaaatttg ctgatttctc aggtcaacca
    29041 aagataactc aaaaaccatt agaaaatcag aaatatatcc tcccccctct agccctccaa
    29101 aatgagttcg cagactttgt agccctggtc gacaaatcac aatttgcttg tgagatagct
    29161 atataaaagt gtggagaaat agcttgaaat ttagtataat atagctaaac tatttgttta
    29221 aagtgagaaa aaaatgggaa attttagctt tcttttaaaa aatgacgaat atgaatcttt
    29281 ttcaaaacct tgcattgaag ctgagaatat gattgctaca tcaactgtgg ctactgcctt
    29341 tatggcgcgt cgtgctttag agcaggctgt ccattggata tatagtcacg attcatattt
    29401 agaagctccc tatcgtgcta ctctatcttc tttagtatgg gatgatgatt ttagggatat
    29461 cgtagattct gaactccaca agcagatagt tctgttgatt cggtggggaa accatgctgc
    29521 tcatggtggt gaaattaagg aacgagaagc gattttagct ttgcatcatt tgtatcagtt
    29581 tgttaatttt atcgattatt gttacagcaa tgagtttgtg gagcgttatt ttgatgagaa
    29641 gtgcttacca ctttcagcaa acatcaaata ccgagaaact ccacaatcta tgataaagtt
    29701 acaagacagt ttaccagaac tgcctgattt tcatgaacag atggctgctc agtccgtaga
    29761 agttcaagag acttatactg aaaaacgtga gactgcagcg caacggcaag atgtgccttt
    29821 ccatattgat caattatctg aggcagagac aagaaagctc tttattgata tcgatctccg
    29881 tttagcagga tggatatttg gagaaaactg ttgtgttgag atagccgttg atggtctcaa
    29941 gcacggttca ggaattggtt actgtgacta tgtactttat ggtaaaaatg ggaaaatttt
    30001 agcgattgtg gaggctaaaa aagcctctgt caatccagaa gtaggggaag tacaggtcaa
    30061 agaatatgct gaagctttgg agaaacatat cggctatcag ccaatttgct ttattacaaa
    30121 tgggttgaag cactatatac ttgatggtcc gaaccgacgc cagattgcag gcttttactc
    30181 tcaagaagaa ttgcaattag tgatggatag acgtcatctt caaaaaccac ttgaggatat
    30241 ttctagtaaa attagggacg atatttccgg gcgtcactac caaaaacatg ccattgcaag
    30301 cgtttgtgaa gctttctcta atcatcgtag acaggcactt ttggttatgg caactggggc
    30361 ggggaaaact cgtacagcag tttctctagt tgatatctta tcacgtcata actgggtaaa
    30421 aaacgttctc ttcttagccg atagaacttc cttggttaag caagcctatg attcgtttag
    30481 aaaattactc ccagatcttt ccgtttgtaa cttcttagaa gataaagaag gagctcaatc
    30541 aagtcgtatg gtcttttcaa cttatccgac catgattgga gcgattagtg gtcaagaaga
    30601 agtaaatcaa cgccctttta ctgttgggca ttttgacctt atcataattg acgaatctca
    30661 ccgttctatt tatcagaaat acaagtccat ttttgattat tttgatgcaa gaattgtagg
    30721 cttaacagct actccgcgtc aagatttaga taaaaacacc tatggattct ttaatttgga
    30781 gaatggggtt ccaacatatg catatgattt ggaagaggct gttaaagacg gatatttagt
    30841 agcctatcat tctatcgaaa ccaaactgaa actacctacg gatggtctac attatgatga
    30901 tttgtccgaa gaagaaaagg aacattttga tagcaaattt gaagacgata gctgtgaaaa
    30961 agatattgat gggagtgtat ttaattcctt tgttttcaat aaaagtacag tagaaattgt
    31021 tttaaatgaa ctcatgacaa gaggaattca gacagcctcg ggtgatgaaa ttggtaaaac
    31081 tattattttt gctaaaaatc atgatcatgc agaatatatc agaggtattt ttaacaaccg
    31141 ctatcctgaa aaagggagcg actatgctca ggtgattgat tatagtatta agcattatca
    31201 gaccttgatt gatgatttta aaattgagga gaagtatcct caaattgcga tttctgtcga
    31261 tatgttagat acaggtattg atgtaccaga ggttgttaat ttagtcttct tcaagaaagt
    31321 acgctctaaa actaagtttt ggcagatgat tggtcgagga acccgtctat gtaaagattt
    31381 atttggacct gagcaggata aggaaaactt cttggtattt gattatgggg ataattttga
    31441 ttattttcgt gcagatccaa gagatggaga gggtcgtcac attgtttcgt tgactcagcg
    31501 tttatttaat atcaaagtgg acttgattcg agaacttcag ggactccaat accaagaaga
    31561 tcagtttgcg agagcatacc gtcagcagct tgtctcggaa cttcaaggtc gtatagagag
    31621 cttaaatgag ttggacttca gggttcgtat ggttttagat acagtttata gctataggaa
    31681 attggaaagt tggcagaatc taactgctgt tacaagtgaa accattcaaa aaaatctctc
    31741 tccgctttta tttgatgaag ataaagaaga tgagatggcc aggagatttg atttgtggtt
    31801 gcttcatatt cagttggggc aactgacagc taaatcttcc actgttcata tttcccaagt
    31861 gatgaagacg gctagagctc tttctgctat tggcaatatc ccgcaggttt ttgagcaggc
    31921 tgaaattatc aggaaagtac aggagcctga attttggaaa gaagttaact tgtctgattt
    31981 ggaaaaaatt cgtcttgcta ttcgagattt attacagttt ttggataaaa cagaccgtaa
    32041 accctactat gttaactttg aagatcgtat actctccact gttcacgaga ccacagcatt
    32101 tttgcaggtc aacgatcttc ggtcttacaa tgaaaaagtt gagcattatt tgaaaactca
    32161 tctggatgag gagtccattt ctaagctata ccataataaa aagttgacat ctgatgatat
    32221 gcttgcactt gaaaaattgc tttgggaaaa attaggtagt aaagcagact accaaagtca
    32281 ttatgaaaat aaggcaattc cgagattggt tcgtgagatt attggcttag atagagagtc
    32341 tgccaatcgt attttttcta aatttttgtc ggatgagaat cttaatgcca ggcagatttc
    32401 atttgtaaaa ttgattgtag actacattgt agaaaatggt tttttagaga cgaaagtgtt
    32461 aacgcaagag ccgtttaaat cttatggttc tgttcaacta ctcttccaac accaactacc
    32521 agtacttcgt aatattgttc aaatcattga acttatcaat aatcgagctg gagaagcggc
    32581 ttaaattcta aagtgattgc catgctgaga ctcatttaaa attaaaaaga gtagaaattt
    32641 atgctatata tgagaagttt tattaggaag aatgtcatcg ttttcctaga atacagtatc
    32701 agttgttaag tggttgataa atttcaaagt agatacttgt accacgatgt ttgttgatcg
    32761 agttattaac aaaagagcta ctttgatttt aaagaaatag aaaacaaaaa gccgagcaag
    32821 aattcaattg caggagaaaa tgaaataata ctcaatgaaa atcaaagagc aaactaggaa
    32881 actagctgca ggctgctcaa aacactgttt tgaggttgca gataagactg acgaagtcag
    32941 ctcaaaacat ggttttgagg ttgtagatga aactgacgaa gtcagtaacc atacctacgg
    33001 caaggcgacg ttgacgcgga ttgaagagat tttcgaagag tataaatctt cctaggataa
    33061 agcaaaacgc atagtatcaa gggttttcaa cacttgatac tatgcgtttt ctgatgttaa
    33121 agactttcta ccagtttttt taagcataat tgttagttgt agtcatttat tattcttcaa
    33181 agaaaaatgg tggggcgaat tttttcagtt cttcaaagca cttttgagca gtatctgcat
    33241 cttcacagat gataagacag acatcattac cacaaagggt agcgatagcg tcagggaagc
    33301 tcaaagtatc aatgatagaa ccaaaggatt gagccagtcc aggaagggtt tttagtagga
    33361 cttggtgttg aactgggcgc atccagacaa gggcgtcttc catgtagagt tcgagacgtt
    33421 tttcccattt tgagatggaa ccattgttaa gaacataata agcgctatct tcttcgcgga
    33481 cttttgatag gttcatattt ttgatgtcgc gtgagagggt tgcctgggtt acttgaatgt
    33541 cgttcttagc aagaagggct tgcaactcag cctgtgtatg aatcttgttt tttgtgataa
    33601 gagcgcgtat aagttggtgg cggtgttctg atttattcat aataatgtaa ctccttttag
    33661 caaggtaagg taagcatgga ctgagcgagg tcgacagtca agtggtagtc tgtattgtca
    33721 cggatggtga tttcaaagtc agtagtatag aggactaaac ggagagtgtc tccttctttt
    33781 agcttgtaaa tagttggctg cagttcaaat tgaacatcca tccattcatc tgcagtaata
    33841 tcctctacta acagtaaatc atttctattt tgtaaattaa ggtaaccttt tgtcacgact
    33901 cgttgtgcct ctggtctaaa tggcaattca cagagatttt ccaacatgtg atagcgaccg
    33961 ttgtcaatgg ttctagcact taaaatagct ggataaggtt gtaggtattt cttttgccca
    34021 aattctagca gttgggcaga taagagcccc ttgtttgtac tggatttgat acgaagattg
    34081 agctgagcgc gaccgtttag gtggagatct ttagtcacag gaaggttaat agtaatctga
    34141 ttggctttcc cttgatagag ctctgtattg aaggtttggt atgtcttacc atagcgctca
    34201 aaatccttat ctgggtactg gttttgaata gcttgctctt cttgaccaag tgagaaggtt
    34261 tcacagtttt cttgcccacc gaagttatca agtgataacc aagtctgtgg agctgtattg
    34321 tcctgccaga taacagtagg aagttgaaag tctgtttcct gtcctagtaa tttcttggtc
    34381 aataaggcat ttatggactc acggaagtca attgattgcc aattgttcat gtaaacatgg
    34441 gcaccattat ggaaaaagag atgcttgttt atatgagtag gaagagcatg gaacatctgg
    34501 taaacatgaa gtggtttgac attccaatcc tgagaaccat gagtaaagac aacctctgcc
    34561 tttactttat gggcattgag cagataattg cggtcatgcc aaaactgatt gtagtcccca
    34621 gtttttcggt ctagctgagc tttcactttt tctaagtcag cttggtgagc ttcattgcca
    34681 cggatatagt cgccagctaa gagattacga gaataggtta actcagcaag ggagtcaaag
    34741 tcctcacctg gataaccacc tgggctagtc accagaccgt tttcacggta gtagttgtac
    34801 catgatgaaa ttcctgcctc ggcaatgata acttctaaac catcgactcc tgtagtcgca
    34861 agaccattgg acatggtacc tagataggaa agtcctgttg tagcaacttt tccgtttgac
    34921 caatcagcct tgacttgacg ctggcgcgtg tgatcagtaa aggcacggca acggccgtta
    34981 agccaatcga tgacattttt ataagcctcg atttgctggt agtctccatt agtcatgaaa
    35041 cctgtcgagt ctttggtacc aacacctgag acatagagat tggcaaagcc tctcggaagg
    35101 aagtagtcgt ttagtgtata gctagagttg atgtgagtta gcttttcctc agcctctgct
    35161 ataagctcag ctttaccttg gggttggacg agatttagtt gaggtttctc tagctcaatc
    35221 ttgtgaggaa gcttaacctc aagctcgccc tccatcttgt agagagcctt gtcactagcc
    35281 ttgtcattgg ttccctgatg ataagggctg gctgtcatga tggcagggat ttttccatca
    35341 aaacgagggc gaataatgct aacctttact aggtctgata gccctttttg gtcagtatcg
    35401 acacgagact caacgtaaac gacttcacga atgacatcct ggttagaaaa agtagccaaa
    35461 ctcttgccgt taaagtagtg gtagtcatta tcctccggaa taagaccatc actaacaagt
    35521 tggtcgataa gagtatttcc ttttttggtg cgagtattga gtaactgata gagattttca
    35581 atcaagtcac catatataat gggaaatcca gtttctttac gaaaaacgtc actatcttcg
    35641 aagtcaacca aataagaaaa gcctaaaagt tgaaaagcaa cagtataaaa aatatctgct
    35701 gtcagttcat cttctgattg aaaaaatgtc agcaggtctg tttttttatc agctgctagg
    35761 atagaaagtg ggtagttggt gtcttgataa gtgaaaaaga aacgacgtaa aaaggtttca
    35821 agtgagtctt tgtgattggc tgtattttgt aaatcaaagc cacatttttt tagttcagat
    35881 aagacatttt cttttggaaa attgatataa ctatattgat taaaacgcat agaacctcca
    35941 tatagaatga cagttaaggt tattatatca aaaaaaaagc agaaagggaa ttgttaactt
    36001 caaaaggaaa taatccaata aaaatgaata aagtactaaa ttcaatatag agaacagagt
    36061 aacaataaga ataaatagat agggtataaa agttctagga gatttatatt atatgctttc
    36121 tatttttata tacaatatag tataaatata aaaatgatga caaaaataca aatgaataga
    36181 aaataaatta gtaagctgat gaaatttttc tcaagagaag ccatttatag gtgaaaatgg
    36241 tataatatag tgagaaggat agaggagaag tgtaaattga tcgcacaact agatacaaaa
    36301 acagtctata gttttatgga aagcgtcatt tcgatcgaaa agtatgtgag agcagctaaa
    36361 gaatacggct acactcattt ggctatgatg gatattgaca atctttatgg cgctttcgac
    36421 tttctagaga ttacaaaaaa atacggcatt catcctttgc tagggcttga aatgacagtg
    36481 tttgtagatg atcaggaagt gaatttgcgc tttttagctc tatctagtgt gggctatcag
    36541 cagttgatga agctttcgac agccaagatg cagggggaga aaacttggtc agtcctgtcc
    36601 cagtacctgg aggatatcgc ggtcattgtg ccttattttg atagagttga gtcgttagaa
    36661 ctaggctgtg attactatat aggggtttat ccagaaacac tagcaagcga atttcatcat
    36721 cctatcttac ctctttatcg ggtcaacgct tttgaaagca gggatagaga agttcttcaa
    36781 gttttaacag cgattaaaga aaatctaccg ctcagagaag ttcccttgcg ttcgagacaa
    36841 gatgtcttta tatcagcaag ttctttagag aaactattcc aagagtgttt tccgcaagct
    36901 ttggacaatt tagaaaagct tatttcaggc atttcttacg acttggatac tagtctgaaa
    36961 ctgcctcgtt ttaatccagc tagaccagca gtagaggagt tgagagagcg tgctgaactg
    37021 gggcttgttc agaaggggtt gactagtaaa gaatatcaag atagactaga ccaagaattg
    37081 tctgttattc atgatatggg ctttgatgat tatttcttgg ttgtttggga tttgttgcgt
    37141 tttggacgat cgaatggcta ttatatggga atgggaaggg gttctgcagt aggcagtttg
    37201 gtttcttatg ccttagacat cacggggatt gacccagtag agaaaaatct gatttttgaa
    37261 cgctttctta atcgtgaacg ctataccatg cctgatattg atattgatat cccagatatt
    37321 tatcgtccag attttatcag atatgttggt aataaatatg gtagtaaaca tgcggcacaa
    37381 atcgttactt tttcaacctt tggagccaag caagctcttc gagatgtctt gaaacgcttt
    37441 ggtgtgccag agtatgaatt atctgcaatt actaagaaaa tcagttttcg tgacaatctt
    37501 aagtcggcct atgagggcaa tctccagttt cgtcagcaaa tcaatagtaa gttagaatac
    37561 caaaaagctt ttgagattgc ttgcaagata gagggctatc caagacaaac ctctgtccat
    37621 gcggctggtg ttgtaattag tgaccaagat ttaaccaact atattcctct aaagtatggt
    37681 gatgaaattc cactgactca gtatgatgct catggagttg aggctagcgg acttttgaag
    37741 atggactttc tgggactacg aaatttgacc tttgtccaga agatgcaaga gttgcttgct
    37801 gaaatagaag gtattcacct taaaattgaa gaaatagatt tggaagacaa agaaacgtta
    37861 gctttatttg cctctggaaa tacaaaaggt atctttcaat ttgagcaacc aggtgccatt
    37921 cgtctgctta agcgtgtgca accagtctgt tttgaagatg tcgtcgcgac tacttctcta
    37981 aatcgaccgg gtgctagtga ctatatcaat aattttgtgg caagaaagca tgggcaggaa
    38041 gaagtgactg ttctggatcc agtactggag gatattttgg ctccaaccta cggcataatg
    38101 ctctatcagg agcaggttat gcaggttgcc cagcgatttg ccggatttag tcttgggaaa
    38161 gccgatattt tgcgtcgggc tatggggaaa aaggatgcct ctgccatgca tgagatgagg
    38221 gcttccttta ttcaaggttc attagaagct ggtcatactg tggaaaaagc agagcaggtc
    38281 tttgatgtta tggagaagtt tgcaggttat ggttttaaca ggtcacacgc ctatgcctac
    38341 tcagccttgg ccttccagtt ggcttatttt aaaacacatt atccagccat tttttatcag
    38401 gtcatgttaa attcttccaa cagtgattac ttaatagatg cacttgaagc aggttttgaa
    38461 gtagcctctc tatccatcaa caccattccc tatcacgata aaattgccaa caaggccatc
    38521 tatctaggtt tgaaatccat taaaggagtc agtaatgatt tagctctctg gattattgaa
    38581 aatagacctt attctaacat tgaagatttt atagctaaat tacctgagaa ttatctgaaa
    38641 cttcctctgc tagaaccttt ggtaaaagtt ggtcttttcg attcatttga aaaaaatcgt
    38701 caaaaagtat ttaataattt agctaatcta tttgaatttg tgaaagagtt gggaagtttg
    38761 tttggagatg ctatttatag ttggcagaaa tcggaagatt ggacggaaca agaaaaattt
    38821 tatatggaac aagagctttt agggataggt gtcagcaaac atccactaca agctattgca
    38881 agtaaggcta tttacccgat taccccaatc ggaaatttgt cagaaaatag ctatgctatt
    38941 attttggttg aagttcagaa aataaaagtg attcgtacca aaaagggtga aaatatggct
    39001 ttcttacagg tggatgacag taagaaaaaa ttggatgtta cactcttctc agatttatat
    39061 cgacaggttg gtcaggaagt aagagaagga gcattctact atatcaaagg gaaagtccaa
    39121 tcacgtgacg gtcgtctgca aatgattgca caagaaataa gagaagcagt tgctgaacgc
    39181 ttttggattc aggttaaaaa tcatgactcg gatcaagaga tgtcacgtat tttagaccag
    39241 tataaaggcc caatcccagt catcatccgg tatgaagagg aacagaaaac catcgtttct
    39301 ccccatcatt ttgtagctaa atctgatgaa ttagaggcga aattgaatgg aatagttatg
    39361 aaaacgattt atcgctaaaa ttacggaaaa tagaagaatt ttcaacgtaa atgtggtata
    39421 atcagtaaga atgttaaaag aaaaaggagc ataaccaata tgaaacgtat tgctgttttg
    39481 actagtggtg gagacgcccc tggtatgaac gctgccatcc gtgcagttgt tcgtcaagca
    39541 atttcagaag gaatggaagt gtttggtatc tatgacggat atgctggtat ggttgccggt
    39601 gaaattcatc ccctagatgc agcttcagta ggggacatca tttctcgtgg tggtactttc
    39661 cttcactcag ctcgttaccc agagttcgct caacttgaag ggcaacttaa agggattgag
    39721 caattgaaaa aacacggaat tgaaggtgta gttgttatcg gtggtgacgg atcttaccac
    39781 ggcgctatgc gtttgactga acatggcttc ccagctattg gtcttccagg tacaatcgat
    39841 aacgatatcg ttggtactga ctttacaatc ggttttgaca cagcggttac tactgccatg
    39901 gacgctatcg ataagattcg tgatacatca tcaagtcacc gtcgtacttt tgtaatcgaa
    39961 gttatgggac gtaacgctgg tgatatcgct ctttgggctg gtattgcaac tggtgctgat
    40021 gaaatcatca tccctgaagc aggcttcaag atggaagata tcgtagcaag catcaaagct
    40081 ggttatgaat gtggtaaaaa acacaatatc atcgtcttag ctgaaggtgt gatgtcagcg
    40141 gctgaatttg gtcaaaaact taaagaagct ggagatacaa gcgaccttcg tgtaacagaa
    40201 cttggacata ttcaacgtgg tggttctcca actgcgcgtg accgtgtttt ggcgtcacgt
    40261 atgggtgcac atgctgttaa acttcttaaa gaaggtatcg gtggtgttgc ggttggtatt
    40321 cgtaacgaaa aaatggttga aaatccaatt cttggtactg cagaagaagg ggcattgttt
    40381 agccttactg cagaaggtaa gattgtggtt aacaacccac acaaagccga tattgagcta
    40441 tctagcttga ataagagctt gttataattt acaatttagt taataagacc aaaaaggtca
    40501 tatatataaa ggagtcacaa aaatcatgaa caaacgtgta aaaatcgttg caactttggg
    40561 tcctgcggta gaaatccgtg gtggtaaaaa attcggtgag gacggatact ggggtgaaaa
    40621 acttgatgtt gaagcttcag ctaaaaacat tgctaaattg attgaagctg gtgctaacac
    40681 attccgattc aacttctcac acggcgacca ccaagaacaa ggtgagcgta tggcaactgt
    40741 taaacttgcg gaaaaaattg caggtaaaaa agttggtttc cttcttgata caaaaggacc
    40801 tgaaatccgt acagaattgt tcgaaggtga agctaaagaa tattcataca aaactggtga
    40861 aaaaattcgt gttgcaacta aacaaggaat caaatcaact cgtgaagtga ttgcgttgaa
    40921 cgttgctggt gctcttgata tctatgatga tgttgaagtt ggtcgtcaag ttttggttga
    40981 cgatggtaaa cttggtcttc gtgtggttgc taaagatgat gcaactcgtg aatttgaagt
    41041 tgaagttgaa aacgatggta tcatcgctaa acaaaaaggt gtgaacatcc ctaacactaa
    41101 aattcctttc ccagctcttg ctgaacgcga taacgacgat atccgtttcg gtcttgaaca
    41161 aggtatcaac ttcatcgcaa tttcattcgt acgtactgca aaagatgtga acgaagttcg
    41221 tgcaatctgt gaagaaactg gaaacggaca tgttcaattg ttcgctaaaa tcgaaaacca
    41281 acaaggtatc gataacttag acgaaatcat cgaagcagct gatggtatta tgattgctcg
    41341 tggtgatatg ggtatcgaag taccgttcga aatggttcca gtttatcaaa aaatgattat
    41401 caagaaagtc aatgctgcag gtaaagttgt tatcactgca acaaacatgc ttgaaacaat
    41461 gactgaaaaa ccacgtgcaa ctcgttcaga agtatcagac gtattcaacg ctgttatcga
    41521 cggaactgac gctacaatgc tgtcaggcga gtctgcaaac ggtaaatacc cactcgagtc
    41581 agtaactaca atggctacaa tcgacaagaa cgctcaagct cttcttaatg aatacggacg
    41641 tcttgattca gattcatttg agcgtaactc taagacagaa gtaatggctt ctgctgttaa
    41701 agatgctact agctcaatgg atatcaaatt ggttgtaact cttactaaga caggtcatac
    41761 tgcacgtttg atttctaaat accgtccaaa tgctgacatc ttagcattga catttgacga
    41821 attgacagaa cgtggcttga tgttgaactg gggtgttatc ccaatgttga cagatgctcc
    41881 atcttcaact gacgatatgt tcgaaatcgc tgaacgtaaa gcggtagaag caggtctcgt
    41941 tgagtcaggc gatgatatcg ttatcgttgc tggtgtgcca gtaggagaag ctgttcgcac
    42001 aaacacaatg cgtatccgca cagtacgtta agaaaaatat aaaaacctat catatccagc
    42061 tttctagcct gtatgatggg ctcttttttt gtccaggggg caaaaagggg gcaaaacttt
    42121 cataatggat tgatactctt cgaaaatctc ttcaaaccac gtcagcgtcg ccttaccgta
    42181 tatatgttac tgacttcgtc agttctatct acaacctcaa agcagtgctt tgagcaacct
    42241 gcggctagct tcctagtttg ctctttgatt ttcattgagt atgaaataag atatgcacaa
    42301 attgattagg aaattcaaat gaatttctac aaatgtttta gcaatcgcaa tctacttgtc
    42361 tagattcgat ctgatatatt ttcgatttaa tgatatggta tttaaaacct ccaaagtagc
    42421 ttgctccatt cttttactta cgtgagtgta gatgttattt actgttttag cgtttttgtg
    42481 ttctactcta accattatag cattcttctc agctagtgta ctaaggagtg tgtgcctgaa
    42541 aatatgggaa ctaagggctg gtttatcggt ttctctagtt tagtatttgc cttttgcaaa
    42601 gtgatcttaa atgcctttct ctaaatttac atatcactat tgtttaacaa aatctaatct
    42661 actttaggtc acttattctt tttttgaaat gtagaatgaa ctttttcaaa gtttttcgaa
    42721 tcttttaaaa tctgtttgtt ttatatcgcc attctccccc ttttttaatt ctccctatat
    42781 agcctgacaa ctttcccgat ggtacgaata tggttgcttt cgtctaggtg gatgtcggag
    42841 tattcgggat tgagtttttt tgaggtagcc ttggcggagt ttcttgacat agttagtgcc
    42901 gtctacttgg aagatgccga tggtattata gtcaatctgt ggggtattct tgataaatag
    42961 gtagtcgctg tttcttatct ttggctccat ggacttgctg acgacataag cgattgggtc
    43021 gtagtcgtct gggataatgg aaactccata actaaatcgt cgtcctgcat caagcggcta
    43081 cctgcagaga taaactacct aacacgagag taagtagtct gtctgtagtc gtccagtctg
    43141 atgattttta cgatacttcg tttttctgat catacagttg cctctcggca taggtcagaa
    43201 ctttaccttg tctgggtggt gcccgttggt cgtagataga ttggatatcg ctaggagaat
    43261 ccttttgaac tggaggaaag agggcatcaa tcaagctact gaatacttta actaagtcaa
    43321 atatagtatt tttcttagta gacctaaccc ttttttcata atttctaatg gtgtttttac
    43381 ttatacctat cttagtaccc aattcttatt gagtccaacc attactagtc tatattgttt
    43441 tatagttgat tgagtttgga atagtacgct gtagctgcta aaacatttct aggaattaat
    43501 ttgcctttcc taatagagtt gttcatatct tatttcaatc tactatattt ttcacctcta
    43561 acaatcgcaa tctcttcttt atccatgaac gaaaacgctt tctatctttg taagtaaagc
    43621 atcacacgaa atccacgaaa atgaaaacct ttgttgtgtt ttcgtaaaaa atttgttgac
    43681 agagcacgaa acgcctacta taattaaatc aagtttaagg aaataacaaa aaaacaaatc
    43741 ggagggaaag acgatgaaca cattaaatga gaaagtaatc aatatctgta aagcagtagt
    43801 taaagaaact ttaatccaag acatttagga gaaagaaatg aagaaatcaa gaaaattagc
    43861 cacattagga atctgttcag ccttgttttt aggcttggct gcttgtcaac aacaacatgc
    43921 tacttctgag gggacgaatc aaaggcaaag cagttcagcg aaagttccat ggaaagcttc
    43981 atacaccaac ctaaacaacc aggtaagtac agaagaggtc aaatctctct tatcagctca
    44041 cttggatcca aatagtgttg atgcattttt taatctcgtt aatgactata ataccattgt
    44101 cggctcaact ggcttatcag gagatttcac ttcctttact cacaccgaat acgatgttga
    44161 gaaaatcagt catctctgga atcaaaagaa gggcgatttc gttgggacca actgccgtat
    44221 caatagttat tgtcttttga aaaattcagt caccattcca aagcttgaaa agaatgacca
    44281 gttgcttttc ctagataatg atgcgattga taaaggaaag gtctttgatt cacaagataa
    44341 ggaagagttt gatattctat tttcgagagt tccaactgag gcaactacag atgtcaaggt
    44401 tcacgctgaa aagatggaaa cattcttctc acaatttcaa ttcaatgaaa aagctcgaat
    44461 gctgtctgta gtcttgcacg acaatctgga tggcgagtat ctgtttgtag gtcacgttgg
    44521 ggtcttagta cctgctgatg acggtttctt atttgtagag aaattgactt tcgaagaacc
    44581 ctaccaagcg attaaatttg ctagtaagga agattgctac aagtatttgg gcatcaagta
    44641 tgcggattat acaggcgagg gactggctaa gccttttatc atggataatg ataagtgggt
    44701 taaactttaa tagtgttatg atatgacagt aatcttagga tttttatttc tatttttgat
    44761 gacttggtgg gttatttcaa tcgttaatag ccagaaacca ctcaaaaatg aaacatttat
    44821 tggctatgtc caaagatacg atattgatgg gaatggctat caatcattac cgtgtcctca
    44881 gaactgagag gagttcttga aatcgtaaca ccactttgaa caagagttac ttcaacccat
    44941 tggctccgcc ggagtaagtt gctttcgtga acaccaaaat cagccgcaat ttcttcataa
    45001 gtgcggtatt ctcacac
//
LOCUS       DAVKEV010000017        43999 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVKEV010000017 DAVKEV010000000
VERSION     DAVKEV010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43999
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.017"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(280..1914)
                     /locus_tag="VWZ68_000892"
     CDS             complement(280..1914)
                     /locus_tag="VWZ68_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371943.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMIICFSNIAIHFPFEEIPIYFSLMIAILLVIAFSTSLTAFYNVFYESK
                     DLISYRPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVALVMVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVDPFSTEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(1895..2644)
                     /locus_tag="VWZ68_000893"
     CDS             complement(1895..2644)
                     /locus_tag="VWZ68_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9371944.1"
                     /translation="MIEFQNVSKLYGDKKALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVED
                     LRKDYPDQSLESIYLSLAGRKEEVADASQGH"
     gene            2823..4277
                     /locus_tag="VWZ68_000894"
     CDS             2823..4277
                     /locus_tag="VWZ68_000894"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEU9371945.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(4367..6985)
                     /gene="alaS"
                     /locus_tag="VWZ68_000895"
     CDS             complement(4367..6985)
                     /gene="alaS"
                     /locus_tag="VWZ68_000895"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEU9371946.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQPKIQELLDAVAGKL"
     gene            complement(7007..7492)
                     /locus_tag="VWZ68_000896"
     CDS             complement(7007..7492)
                     /locus_tag="VWZ68_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEU9371947.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(7767..8006)
                     /locus_tag="VWZ68_000897"
     CDS             complement(7767..8006)
                     /locus_tag="VWZ68_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371948.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLNDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(8275..9345)
                     /locus_tag="VWZ68_000898"
     CDS             complement(8275..9345)
                     /locus_tag="VWZ68_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9371949.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGSEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(9342..10115)
                     /locus_tag="VWZ68_000899"
     CDS             complement(9342..10115)
                     /locus_tag="VWZ68_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9371950.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(10112..10918)
                     /locus_tag="VWZ68_000900"
     CDS             complement(10112..10918)
                     /locus_tag="VWZ68_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9371951.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(10899..12056)
                     /locus_tag="VWZ68_000901"
     CDS             complement(10899..12056)
                     /locus_tag="VWZ68_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9371952.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(12217..13122)
                     /gene="murB"
                     /locus_tag="VWZ68_000902"
     CDS             complement(12217..13122)
                     /gene="murB"
                     /locus_tag="VWZ68_000902"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEU9371953.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(13234..13986)
                     /locus_tag="VWZ68_000903"
                     /pseudo
     CDS             complement(13234..13986)
                     /locus_tag="VWZ68_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            complement(13996..14727)
                     /gene="budA"
                     /locus_tag="VWZ68_000904"
     CDS             complement(13996..14727)
                     /gene="budA"
                     /locus_tag="VWZ68_000904"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEU9371954.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            complement(15211..15732)
                     /locus_tag="VWZ68_000905"
     CDS             complement(15211..15732)
                     /locus_tag="VWZ68_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcin A-M57"
                     /protein_id="HEU9371955.1"
                     /translation="MKFKKIVTSALVVLSLFSIMSPSIASVRVFADDVTTTEVSEIST
                     QEQKQIDDVANVLEQMFRNGVNEKNFTEYVYKNFSQKDIALAENELETNINNPYDRVP
                     WDEMGGCIAGKIRDEFFAMINVSLIVKYAQKKAWSELAKVVLRFVKANGLKTNIYIIA
                     GQLAIWAVQCGLE"
     gene            16163..17434
                     /locus_tag="VWZ68_000906"
     CDS             16163..17434
                     /locus_tag="VWZ68_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEU9371956.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(17454..18269)
                     /locus_tag="VWZ68_000907"
     CDS             complement(17454..18269)
                     /locus_tag="VWZ68_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU9371957.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(18426..19079)
                     /gene="phoU"
                     /locus_tag="VWZ68_000908"
     CDS             complement(18426..19079)
                     /gene="phoU"
                     /locus_tag="VWZ68_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU9371958.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(19091..19849)
                     /gene="pstB"
                     /locus_tag="VWZ68_000909"
     CDS             complement(19091..19849)
                     /gene="pstB"
                     /locus_tag="VWZ68_000909"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU9371959.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLNPQHKETEDYITGKFG"
     gene            complement(19862..20665)
                     /gene="pstB"
                     /locus_tag="VWZ68_000910"
     CDS             complement(19862..20665)
                     /gene="pstB"
                     /locus_tag="VWZ68_000910"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU9371960.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(20676..21560)
                     /gene="pstA"
                     /locus_tag="VWZ68_000911"
     CDS             complement(20676..21560)
                     /gene="pstA"
                     /locus_tag="VWZ68_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU9371961.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(21550..22467)
                     /gene="pstC"
                     /locus_tag="VWZ68_000912"
     CDS             complement(21550..22467)
                     /gene="pstC"
                     /locus_tag="VWZ68_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU9371962.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(22467..23345)
                     /gene="pstS"
                     /locus_tag="VWZ68_000913"
     CDS             complement(22467..23345)
                     /gene="pstS"
                     /locus_tag="VWZ68_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEU9371963.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(23919..25223)
                     /locus_tag="VWZ68_000914"
     CDS             complement(23919..25223)
                     /locus_tag="VWZ68_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEU9371964.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(25224..25997)
                     /locus_tag="VWZ68_000915"
     CDS             complement(25224..25997)
                     /locus_tag="VWZ68_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEU9371965.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGHLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(25987..26265)
                     /locus_tag="VWZ68_000916"
     CDS             complement(25987..26265)
                     /locus_tag="VWZ68_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEU9371966.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(26265..26666)
                     /locus_tag="VWZ68_000917"
     CDS             complement(26265..26666)
                     /locus_tag="VWZ68_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEU9371967.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(26876..27493)
                     /locus_tag="VWZ68_000918"
     CDS             complement(26876..27493)
                     /locus_tag="VWZ68_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEU9371968.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(27483..28256)
                     /locus_tag="VWZ68_000919"
     CDS             complement(27483..28256)
                     /locus_tag="VWZ68_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEU9371969.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(28267..29004)
                     /locus_tag="VWZ68_000920"
     CDS             complement(28267..29004)
                     /locus_tag="VWZ68_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEU9371970.1"
                     /translation="MCLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            complement(29009..30139)
                     /locus_tag="VWZ68_000921"
     CDS             complement(29009..30139)
                     /locus_tag="VWZ68_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEU9371971.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(30223..30612)
                     /locus_tag="VWZ68_000922"
     CDS             complement(30223..30612)
                     /locus_tag="VWZ68_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU9371972.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(30628..31011)
                     /locus_tag="VWZ68_000923"
     CDS             complement(30628..31011)
                     /locus_tag="VWZ68_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEU9371973.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(31012..31800)
                     /locus_tag="VWZ68_000924"
     CDS             complement(31012..31800)
                     /locus_tag="VWZ68_000924"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEU9371974.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFSLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(31793..32728)
                     /locus_tag="VWZ68_000925"
     CDS             complement(31793..32728)
                     /locus_tag="VWZ68_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEU9371975.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(32858..33034)
                     /locus_tag="VWZ68_000926"
     CDS             complement(32858..33034)
                     /locus_tag="VWZ68_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEU9371976.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(33174..33881)
                     /locus_tag="VWZ68_000927"
     CDS             complement(33174..33881)
                     /locus_tag="VWZ68_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEU9371977.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            34032..35060
                     /gene="queA"
                     /locus_tag="VWZ68_000928"
     CDS             34032..35060
                     /gene="queA"
                     /locus_tag="VWZ68_000928"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEU9371978.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKIVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(35721..36110)
                     /locus_tag="VWZ68_000929"
     CDS             complement(35721..36110)
                     /locus_tag="VWZ68_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU9371979.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(36214..36855)
                     /locus_tag="VWZ68_000930"
     CDS             complement(36214..36855)
                     /locus_tag="VWZ68_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002871528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU9371980.1"
                     /translation="MNTSFAHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRFEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTEQVTVD
                     RKEATDTVIKVPAKSKIEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYNV
                     DGKSGQVTESTLSQKKTLKQELLKKEPSPKFLSKKFQSKQNISMAQLLIKVKK"
     gene            complement(37569..38120)
                     /locus_tag="VWZ68_000931"
     CDS             complement(37569..38120)
                     /locus_tag="VWZ68_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9371981.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSTENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(38519..39343)
                     /gene="nadE"
                     /locus_tag="VWZ68_000932"
     CDS             complement(38519..39343)
                     /gene="nadE"
                     /locus_tag="VWZ68_000932"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEU9371982.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(39340..40800)
                     /locus_tag="VWZ68_000933"
     CDS             complement(39340..40800)
                     /locus_tag="VWZ68_000933"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEU9371983.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIYNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFPEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DENGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(40916..41404)
                     /locus_tag="VWZ68_000934"
     CDS             complement(40916..41404)
                     /locus_tag="VWZ68_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371984.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(41394..41603)
                     /locus_tag="VWZ68_000935"
     CDS             complement(41394..41603)
                     /locus_tag="VWZ68_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9371985.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(41988..42716)
                     /locus_tag="VWZ68_000936"
     CDS             complement(41988..42716)
                     /locus_tag="VWZ68_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9371986.1"
                     /translation="MKLNKLNFLKESIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYAWNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVLITTIILLYFFTLKKSKKYSF"
     gene            complement(42732..43523)
                     /locus_tag="VWZ68_000937"
     CDS             complement(42732..43523)
                     /locus_tag="VWZ68_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000928765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9371987.1"
                     /translation="MNFALNKGEIVGLVGRNGVGKSMLMKILAQNNQPTSGNIISSDN
                     IGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLAVLKNLALHENVGILISSHKL
                     EDIEEICERVLFLESGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
BASE COUNT        13325 a         9823 c         8069 g        12782 t
ORIGIN      
        1 taaaatttca cctatttgca tcattctatt tcgaactcta aatatatgtt ctatcaaaaa
       61 tacttggatc acacacatta taggaattaa cgtttttgaa attgaaaaat atcccaataa
      121 ataaactata aacaacaata atagaactat attatatttc ttattcaaaa cattcctccc
      181 tatatttttg attaccaatc ttaatcattt acaactacat tctaacaaac tataaaagcg
      241 tttgtcgaat tgaatttatc aagcaagcaa ccaaccagct catctttttt ctatttctgc
      301 caatatgcgt gacaggtaat aatgatagcc aaaaatagca agagcaagca agacgataag
      361 agctcctact cccaagttga tggcaaggat aggggagaga gactgaacca agaatatgct
      421 cccaattaca agggccatca ggattgcact ataaataaac aataaaacta tggcgactat
      481 gccatttgaa cgattcacca ggtccgtaat gctactccaa ttggttgaca gatttttaac
      541 gtccttaaag taatggtggc aagaaaggat gacactggca aggatccatg ccacaataag
      601 gtaaatcatc gaaatgatgg gcaagcctag atatagagaa agaccaagca aagtcagaac
      661 tggtaaaaag gactggacag catatataat ccaaaatttc actttcacat aacgagcaaa
      721 gtcaaagggt aaactcttaa gaaaatcaac attttccctc tccaaggaca aggcaattga
      781 atgcaggctg gtgatattgt tattgacaac tgctataaac actcctacaa aaaacaaggg
      841 taaccagtat ggaggatgaa tgtctggaac tatctgagaa tctcggattt tggaaatcag
      901 accgatcatc atgagataag gaaagaaagc acttgtaaaa agcactgtaa ccacgccagt
      961 accctgtccc aagagggtga ggtggtagcg taaaaccatg cggaaaaatc cctttttagt
     1021 ggttgaaatt ctctccttgc tgcgacgttc ttttttgacc ttctcctcac tattaagcag
     1081 gatcacgtca taaaaacgag gaaggacctt ctttttggtc agataaagca ggaagagagt
     1141 tagtcctatc caagcgagca gacccaatat ggcttctgtc gaaaaaggat ccactgctat
     1201 tttgtaaaag atatgaagag gataaaggag aaatggaatg tctctaactt tgtcaacaat
     1261 acttccaaaa gtcgactgaa gaaagaagat aaatattaaa ggtatgagaa ctcctatccc
     1321 aatcatcaca ttcgaaaaaa tagactgata ctttctgaag accctagttt gagccaagaa
     1381 atgcactgcc actaccatca ctagagccac agagacaaat aataaggtca aggacagtag
     1441 catcaaaggc aaacccagcc atagagaagg agctagccta atgtagagga ccagaaaata
     1501 agctaggatt ggtacaattc cagttagagc tggcaaaagg acagacagtc ctttagcaat
     1561 tataatctct gattctttaa aggcataggg cctatacgat atcaaatcct tactctcata
     1621 aaagacattg taaaaggccg ttaaagaagt tgaaaaggca atcactagta aaatagcaat
     1681 catcaagcta aaataaatag gtatttcctc aaaaggaaaa tgaatggcta tattactaaa
     1741 acagatgatc atcaagagac tggaaaaaat gtaagaactt aagactctag cggaaacatt
     1801 tacttttttc ccaggattct tagcctgctt ctttcgtaga ttagccagat tagcttcttg
     1861 agatgaataa aggatattga tatcaactaa ttttttaatg accttgagac gcatccgcaa
     1921 cctcctcttt tctaccagca agactaaggt agatactttc caaagactgg tctgggtaat
     1981 cttttctcaa gtcctctaca ctaccacaat aaatcaaatg cccctttttc aaaatggcaa
     2041 tccgatcaca gacttgctct gccacctcta ggacatgagt tgaaaacaag actgtcttcc
     2101 ctttttgtgc atgttccttc atcatctgtt tcaaatcaaa ggcagcctgg ggatccaaac
     2161 cagtcaaggg ttcatccaag acccaaatat cgggatcaga caagagtgct ccgatgacaa
     2221 agactttctg acgcattccg tgagaaagag tttcaataac ctgatagcga ttttcagcaa
     2281 aatcaaaaac gttcaatagc ctagctagac tagcctccaa gtcagatcta ctcagatcat
     2341 aggatgaggc gatcaattcc caaaattcat tggccgttaa gcgtaaaaat aagtcaggcg
     2401 agtctgctac gtagccaatc tttcgtttaa tagccaagcg attttccgat aactcctgac
     2461 cgtctaccaa aatacgacca ctgctgggtg aaatgatact gactagggat tttatagtgg
     2521 tcgattttcc agccccatta tgaccaatca agcccataat ctctccattt tcaatctgca
     2581 aattgagatt actcaaggcc tttttatcac catacaactt actaacattt tgaaattcaa
     2641 tcatgggaca actcctatct ttatctgtat tatatatcgc tatactagca ctttgataca
     2701 aaaaaatcaa tactttattt taagtagtta aaatagtttc cttctatctt acgcaaacgt
     2761 ttgcgctaat agatacttta tgatagaata aagaacaaga ttgacaagta agaggaaaca
     2821 ttatgcaaaa tcaaacactc atgcaatact ttgaatggta tctgccccac gacggtcaac
     2881 actggacgcg tctggctgaa aatgctccac acctagctca tctggggatc agtcacgtct
     2941 ggatgccacc agccttcaag gcaaccaacg aaaaagatgt cggctatggg gtctatgact
     3001 tatttgactt aggagagttc aaccaaaaag ggactgtccg caccaagtat ggtttcaaag
     3061 aagactatct tcaagccatt caagccctta aagcgcaggg aattcaacct atggccgatg
     3121 tggttctcaa ccacaaggct gctgctgatc acagggaagc ctttcaagtt attgaagtgg
     3181 atcctgtaga ccgtacagtt gaacttggag aacccttcac catcaatggc tggactagtt
     3241 ttaccttcga tggtcgccaa gatacctaca atgacttcca ctggcactgg taccacttca
     3301 caggtacaga ctatgatgcc aaacgccgta agtctgggat ttatctgatc caaggggaca
     3361 acaagggctg ggctaacgag gaattggtcg ataacgaaaa cggaaactac gactacctca
     3421 tgtatgccga cctagacttt aaacatcctg aagtcatcca aaacatctat gactgggctg
     3481 attggttcat ggaaacgact ggtgtagctg gtttccgttt ggatgccgtt aagcatattg
     3541 actctttctt tatgcgcaac ttcatccgcg atatgaagga aaaatacggt gacgatttct
     3601 atgtttttgg tgaattttgg aacccagaca aggaagccaa tctggactat ctcgaaaaaa
     3661 cggaagaaca ctttgacctt gtcgatgttc gtctccatca gaatctcttt gaagccagtc
     3721 aagctggcgc aaactatgac cttcgtggca ttttcacaga tagcctggtt gaactcaagc
     3781 ctgacaaggc tgtgactttt gtcgacaacc acgataccca acgaggacaa gcccttgagt
     3841 ctaccgttga agaatggttc aagccagcag cctatgccct cattttgtta cgccaagacg
     3901 gccttccatg tgtcttttac ggagactact atgggatttc aggccagtat gctcaagaag
     3961 atttcaaaga aatccttgac cgcctcctag ccatccgaaa agatttggcc tatggagaac
     4021 aaaatgacta ctttgaccat gctaactgta tcggttgggt acgttcaggt gctgaaaatc
     4081 aatccccaat cgcagtcctt atctcaaatg accaagaaaa cagcaagtca atgtttgtcg
     4141 gtcaagaatg gactaatcaa acctttgtag atttacttgg taaccaccaa ggtcaagtta
     4201 caattgatga ggaaggttat ggacaattcc ctgtctcagc tagatccgta agtgtctggg
     4261 cagtcaatac catctaatag ctcataataa ccaagctagg tccaagcgga tttggctttt
     4321 ttgtattcac aaaaagacct acccaaatgg atagatcttt acttgattac aatttacctg
     4381 ctactgcatc caacaattct tggatcttag gttggttgct tcctcctgcc atggccatgt
     4441 ctggtttacc accaccacgt ccatcgatga ttggtgctaa ttctttgaca aggtttcctg
     4501 catgaaggtc ttttgtcttg cttgctacaa ggacattgac tttgtcaccg atagcggcaa
     4561 ctaggacaag aagatcagag tagtcttttt gtttccagtt atctgcaaag gtacgaaggg
     4621 cacctgcatc ggatacagac acttgactag caatgtaacg atgaccgttg acttccttaa
     4681 catctttgaa gatatcgcct gcggctgcag ctgcggcttt ttctttcaac tcagcatttt
     4741 ctttttgaag ttgacgaagt tgttcttgaa gtccttctac cttgtgaggt acttccttga
     4801 cttgaggtgc tttcaaggtt gctgcgacag ctttaagagc atcctcttgt tcacgatagg
     4861 cttcaaaggc ttccttacca gtcactgcca agatacggcg agttcctgaa ccgattcctt
     4921 cttctttgac aattttgaag agaccaatct cagaagtgtt gccaacatga gtaccaccac
     4981 aaagttcaat agagtagtca ccgatagtca cgacacgaac ttccttgccg tatttctcac
     5041 caaagagggc catagctccc atttctttag cagtgtcaat atccgtttca actgtcttca
     5101 cttcaagtgc ttcccaaatt ttctcgttaa cttgctgttc aatcgcacga agttcctcag
     5161 cagttactgc ttggaagtgg gtaaagtcaa agcgaaggaa ttcaacttcg ttaagagatc
     5221 ctgcctgtgt tgcgtggttt ccaaggatat tgtgaagggc agcgtgaagc aaatgagtcg
     5281 cagtgtggtt tttcatgaca cggtgacggc gattgctatc aattgccaag gtatattctt
     5341 ggttcaaggc aagcggtgca aggacttcaa ctgtatgaag ggcttgacca tttggggctt
     5401 tctgaacatt ggtcacagta gccacaatct tacctgactc atccaagatt tgtccgtagt
     5461 cagctacctg tccacccatt tcagcataaa atgacgtttc cgcaaagata agagaggcag
     5521 ttccttctga aacagctcct acttctgcat tgtcagcaac gatagctacc aatttagaag
     5581 acaattggct agtattgtag ttgaagacac tttctacagt gatgttttga agagtttcat
     5641 tttgcatacc cattgagcca cccttgacag ctgacgcacg cgcgcgttct tgctgttctt
     5701 tcatggctgc ttcaaaacct tcacggtcta cagtcatacc agcttcttca gcgatttctt
     5761 cagtcaattc aactgggaac ccataagtat catagagttt aaagacatct tgaccagcaa
     5821 tgacagattg acctttttct ttcaagtctg ccacaatgcc ttgggcaaag tgttgacctg
     5881 agtgaagggt acgggcaaat gattcttctt cgctcttaac gattttctca ataaagtcac
     5941 gtttctcaag cacttctggg tagtagcttt ccatgatttt tccaacagtt ggaaccaatt
     6001 tgtaaaggaa aggctcgttg atacccaatt tttgaccatg catagaagca cgacggagaa
     6061 gacgacgaag aacataacca cgaccttcat ttcctggaag ggcaccatca ccgatagcaa
     6121 atgaaagaga acgaatgtgg tctgcgataa ccttgaagct catgttgtcg ccatcttggt
     6181 cataaacctt accagacaat ttctcgactt cacggataat cggcatgaag aggtccgttt
     6241 caaagttggt cttagcccct tggataacgg ccaccaaacg ctccaaacca gcgcccgtat
     6301 caatgttctt atgtggcaat tccttgtatt cgctacgagg aacagcaggg tctgcgttaa
     6361 attgtgacaa aacgatgttc cagatttcaa tataacggtc gttttcaata tcttctgcaa
     6421 gcaggcgaag accgatattt tctgggtcaa aggcttcccc acggtcaaag aagatttctg
     6481 tatctggtcc agaaggtccc gcaccgattt cccagaagtt gtcctcaatt ggaatcaagt
     6541 gacttggatc cactcccact tcaatccagc ggttgtaaga atctttatcg tctggatagt
     6601 aggtcatgta aagtttttca gcagggaaat caaaccattc agggcttgtc aaaagctcat
     6661 aagcccaagt gatagcttcg tcacggaagt aatccccgat agagaagttc cccagcattt
     6721 caaacatggt atggtgacgc gcagtcttcc ctacgttttc gatgtcgttg gtacggatag
     6781 ccttttgggc attggtaata cgtggatttt cagggataat ggtcccgtca aagtatttct
     6841 taagggttgc taccccagag ttgatccaca aaagagttgg gtcatttaca ggaaccaaac
     6901 ttactgatgg ttctactgag tgacctttgg tcgcccagaa atcaagccac atttggcgta
     6961 cttgtgcact agatagttgt ttcatattgt ctccttattc acttgtttaa tgtgattggc
     7021 tttccagcat ttccacatag tcaatcgcga cacagaggga aatgactagg tctgcataag
     7081 cgtcttcaag aaccgttacg gtataggtag aggtcagatg gaagagttcc ttcttaattt
     7141 ccgcaatcaa ctgatcgcga tcatccagca atttgaaatt caaatcccag atattgccct
     7201 cgatacgaag acctagatta tcaaactcat acttatctcg ccagaaggtc aacttcttac
     7261 gaatgacaaa actcgagcca tcccgaagct gaatctcaaa acgaggaagc aaggtcaaga
     7321 tttctttact gatctgactg acttgttcac cagccgcatc atagatggta aaagttttgg
     7381 gaatcttaaa aaatgatccc tccacctgat aggcaatttc tcccctgtca tccttgatag
     7441 cgaagcgttc gcctccaaga cgaaactttt gtttgacaag aaatgttttc atcaacacct
     7501 ccaaaaatca aaagacaagc tcatatcacg aagggcgaaa aaccgcggta ccaccttcat
     7561 tcaatgaact tgtcattctc ttgttcttat gcaattgtat gattgagtag catgacttcc
     7621 tagcttagat ggctcgcagc accgccattt ctctggacta agacaagtga aaatcaattc
     7681 tcaactttct tattataacg tttttttaag cttgcgtcaa ctggaaatga tctccgttga
     7741 attagaccaa ttccctacat ctctgattac tttttcagga tatatttttt cttactgcca
     7801 tttttctttt tatcccaaat tttcatatta ctaaacacag ctactagaat atttccaaat
     7861 ataaaggtgc ctatcaccca atatatggac tcagttgtta ggtattgtcg atccaagcca
     7921 tcatttaaat ggaatagtat agcagtttgg ttaacaatca taaaggttgg ccagaaactt
     7981 tttttgaaaa aagtagacat tttcattatt tgttgccgct ttctgtaagg ttaatactca
     8041 ataaaaatca aaaagcaaac taggaagcta gcctcaagct gtacttgagt acggcaaggc
     8101 aacgctgaca tggtttgaag agtataggct tagtatacta ctaggcaagc aaataagcaa
     8161 ataagcaaat aagcaaataa acaactagaa tagaaaaaga tagggctcta aaaactgact
     8221 tctattcctt aaaaacgaac cagcttgact gattcgtctt cttacgttta tctcctactt
     8281 ccgatacatt ttaaactgta ggaagaggtc gctatatttc cctgtccatt tatggtcaaa
     8341 tttctcataa acttctaggt gtttcatggt ttcaacatcg ggatagaagg ccttatcttc
     8401 ctttgtttcc tctgggagca attccttcgc tggtaggttt ggtgttgaat agccgacata
     8461 ctccgcattt tggagagcat tttcaggttt caacataaag ttgataaagg cataggctga
     8521 gttttggttt ttaactgttt tgggaatgac catattgtca aaccaaagat tgctggcctc
     8581 tgtcggtacc acataacgta gattttcatt tttttctaac atttggctgg cttcaccaga
     8641 gaaggtcacg ccgattgcaa cattattctg aatcatatag cccttcatct cgtccgcaac
     8701 gatagccttg atatttggag tcagtttgta gagcttatcc actgtctctt ccaactgctg
     8761 cagatccttg gagttgaggc tgtagccgag ggaattgagt cctagtccca gcacctcacg
     8821 cgccccatca aagagcatga tagaattctt atactccggc ttccaaaggt catcccaatg
     8881 ctcaggcgct tcatctacca tggtttcgtt gtagacaatt cctaaggttc cccagaagta
     8941 agggatggag aatttattac ctgggtcaaa ggactggttg agaaactctg atccgatatt
     9001 ttcgattcct tcaatttttg aataatcaag cggaaccaag aggtcttcgt ccttcatctt
     9061 gttaatcatg tattcacttg gaatggcaat atcgtaggtc gttccaccct gctttatctt
     9121 agtgtacatg gcttcgttgg agtcaaaagt ctcgtactga acttgaattc ctgtttcttc
     9181 tgtaaactga gtcaagagtt caggatcgat atagtctccc cagttataga taaccaattt
     9241 ttgactatct cgactattga ttttactatc taaatgagtc gcaattcccc acaagacaag
     9301 gataatcgct gcaattcctg ctaaaaatga atagattttt ttcatgcttg ctcctccttc
     9361 tcacgagaga taaagtaata acctacaact aggataatac taaagagaaa gactagagca
     9421 gacagggcat tgatttctaa ggaaatcccc ttgcgagcac gagagtaaat ctcgactgat
     9481 agggttgaaa agccatttcc tgttacaaag aaggtcacgg caaagtcatc taacgaatag
     9541 gtgaaggcca tgaaataacc agtaatgata gacggagtca ggtaaggaag catgatttcc
     9601 ttgaacatct gaaattgact agctcccaag tcataggccg catgaatcat gtcgccattc
     9661 atttccttga gtcgaggcaa gaccatcaag accacgatag gaatggagaa ggccacgtga
     9721 ctagatagaa cggtcaaaaa gccaagtgaa aacttgagtt gggtaaagag aatcaagaag
     9781 ctagcaccaa tcataacgtc aggcgcaacc atgaggatat tattgagtga tagaaaggct
     9841 tcttggtatt tcttacgaga ctggtagatg taaatggcac caaaagtccc gataatggtc
     9901 gctatcaagg ctgataggaa ggccaagaaa aatgtctgag ccaaaatcag catgagtctc
     9961 ccatctccaa acatggtttc aaagtgagtc cagctaaaac ctgtaaagct attcatatca
    10021 tcaccagcat taaaggcata gccaatcaag taaaagatag gcaggtagag gaccagaaag
    10081 accagtccca gataaaggtt ggcaaatttt ttcatcgttc tctcctttcc ttagtcaccc
    10141 acatggtgat gaacatggtc aggatgagaa tcacaccgat ggttgaaccc ataccatagt
    10201 tgtcattggt tagaaaattc tgctcaatag ccgtccccaa ggtgataacg cggttcccac
    10261 caatcaaacg ggtcagcatg aagagactca aacttgggat aaagaccgac tgaaccccac
    10321 ttcgcacacc gttcatagat agagggaaga tgacatgacg gaaggtctcc cacttagttg
    10381 caccaaggtc ataactagca ttgatgagat tattatccat atcgtctaag acattgaaaa
    10441 tcggcaaaat cataaagggg agctcgatgt agcttgcgac aaagataaag gaaaaatcgg
    10501 taaaaagcaa ctgttgtgaa ccaattccga taaattccaa gaattggtta atagagccat
    10561 tttgaccaaa aatcccgata aaagcatagg ctttaaggag caaattgatc caggtaggaa
    10621 ggataatcag catgagccag agttgacggt gcttgagacg ggtcaaaaag agggctgttg
    10681 gatagctgat aagcaaggtc acaaaggtca caatccctgc ataaagcact gagttgaaac
    10741 tcattttgag gtaggtcaag ttttgtgacg caaagtaaga tttataattt tctaaactaa
    10801 actggccttc aatgttgaaa aaggattgtc cgaaaatcaa gaccaagggt gccaatacaa
    10861 agagggcaat ccaaagcatg tagggcacta caaagagttt agagcttgtt ttcttcatct
    10921 ctttcctcct cgatcgcatt gatcagacct gcttcttgct cttcgatttc cacgtattct
    10981 tcgatacgag catcgaactc ttcttcggtt tcattgagac gcatgatgtg gatgtcttct
    11041 gattcaaagt ccagaccgat ttcctcaccc acgatggcct tacgggttga gtggatcatc
    11101 cattcatttc caagttcgtc ataggcgata atttcataat gaactccacg gaagagctgg
    11161 gtgtcgacct taacttggag tttgccttct tcaggaaggg taatgcgcaa gtcctctgga
    11221 cgaataacga cctcaacagg ttcatttggc ttcatcccac catcaaccgc ttcaaagcgt
    11281 ttgccgttaa attcgaccaa gtagtcctca atcatggtac ctggcaagat gtttgactcc
    11341 ccgataaagg tggcaacaaa gtggttgatt ggctcatcgt agatgtccac aggggttcca
    11401 gactggacaa tctcgccatc attcataacg aaaatccagt cactcatggc aagagcttct
    11461 tcctgatcgt gagtgacaaa gacaaaggta atgcccaatc gttgttgtaa ttcacgcaat
    11521 tcgtactgca tgtctgttct caatttcaag tccagcgctg ataaaggctc gtccaacaag
    11581 accacacggg gttggttgat gatagcacgg gcgatggcca cacgctgacg ttgtcctcca
    11641 gaaagtttgc ggatggaacg tttttcataa ccttccaact gaaccatctt gagaacttcc
    11701 gctacgcgtt gctcgatttc tttcttgtca atcttgcgca agcgaagtgg aaaggcaaca
    11761 ttttcaaaca cattcatatg tgggaacaag gcataggatt ggaagacagt atgtacgtcg
    11821 cgcttgttgg ttggaatatc attgatacga acaccgtcta gcatgatatc tcctgtcgtc
    11881 gcatccagta aacctgcaat aatgtttagg atagttgatt tccccgaacc agatgcacct
    11941 agaagggtgt agaatttccc ttcttccaac tcaaagttga tgtctttgag aaccttggtg
    12001 ttgctgtctt caaaaacttt agagacgttt ttgaattcga taattggttt tttcaattgg
    12061 cataaattcc ttctttttca tagattaacc gatcggggct ctgtcaggtc cccactacct
    12121 cttgcaggga gtaaaaccac ctgcatacat cttcgctacc gataggcttt cacccccctt
    12181 tccatgacat agcagcagct tttcaaatac agcttcctac ttgctttcac ccaagatccg
    12241 gacttctctt tcaagcgtaa tacctgagtg ttccttgact ttttcgataa ccgattggat
    12301 caagtcctcg tagtctttgg ccgttccatc tgcgacattg atcataaatc ctgcatgctt
    12361 ttctgacact tctacgccac cgatacgata gcctttcaag ccagcttctg aaattaactg
    12421 acctgcaaaa tgcccgactg gacgcttaaa gaccgagcca caagatgggt attccaaagg
    12481 ttgcttgagt tcacgtaggt gcgtcaagcg gtccatttcc tgcttgataa cctgatgggt
    12541 tcctggggct agggcaaatt taactgacaa gacaactgca ccagactcct gaatagctga
    12601 atggcggtaa ccaaaagcca agtctttagc agacagggtt tcgatttctc catccttggt
    12661 caagacctta caagactgca atatgtgagc aatctcgcca ccataggcac ccgcattcat
    12721 aaagacagca ccgccaacgc ttcctggaat accacaagca aactcaaagc cagtcaaact
    12781 atgacggagg gcaatgcgag ttgtttcaat caagttagcc ccagcttctg cttcaatggt
    12841 atagccatca acagaaacgt tattgagctt gtcacacaag atgacaaatc cacgaatccc
    12901 accatcacga acgatgatat tgcttgcatt gccaagaacc atccaaggga tattttcttg
    12961 gttggcaaat ttcacaaggc gagccaactc aaaacgattt cgtggaaaga ccaaataatc
    13021 agcctctcca cctacttttg tataactata gctatgcaag ggttcctgaa aacggatatc
    13081 aattccttct aagatttcaa gcattttttc tcttacagac atgtcactct tccttttaca
    13141 aaattcattc cattatacca tttttagaga catttgacga ccataaaaat accttgtttg
    13201 gattttgcat aagaaaaaga ggttcccctc tttttatgat tttttacaaa agatttcctt
    13261 ggttccatag gcgaccagaa cgagctccag tgctagaatc acttcaacca agactggatt
    13321 tgtcaaccag cctacttgga aaagagatgg tgccagatca aagaaggcat gcaagccata
    13381 ggctgttagg agataaatcc atttcttctg gcgaacagct tgataaaccc aaactgtcaa
    13441 aagtaattgg aaaccaagcg ccaagattcg ctcaaaacca agcaaataaa tctgccagac
    13501 cgaaagtgac tgaatggttt ttaacatatt ttcagacagt aattgcataa cctgtggatt
    13561 ctgagtttga actgccgaaa gaacaatgta aagattgagt aaactagtaa ggcctagaaa
    13621 aatcaactcc aagccaccat gccccaatcc ataggccaag gcgtctgcct tttccaaact
    13681 tctctttttc tccaaccatt tgaagaaaac aagacgagcc gtttcctcaa aaaatgctac
    13741 catggctagg ccatagataa tatagataag cggatgaact tacaagaggg caatactacc
    13801 gtctttttga ggatgcaaaa tcaagatatg caccagtttt tccaaaatct gcgaagagac
    13861 aaagaaagcg actgcaccca agtccaagac agctagatta atctggtatt tctttttggc
    13921 aaaccaaatg cttcctatca gaaaagctag caacagcaac atggtaataa tgatatgaat
    13981 ggtcattttc ttctcctatt ctgccttttc aatatctttt ttcatctcgt caacattgaa
    14041 cttagcaaac aagtattgac ggtcttggac tgggaaacgt tggtccaact ggtcaactgc
    14101 tcccacctcg ataatgcctt ccttgatgac aaaatccatg acatgtccac cgaaggtcaa
    14161 atcatctgat atgaagtgca gatggtagcc tgccacactg accccatgga aaatctcagg
    14221 cgtccagaaa ccaacaatag tccccgcaac attgtcacga ctatattccg gttgatgggt
    14281 tgcgacatca gcaaacttgg tatcgggtgt tgacttagga atcatacgca catgcatatg
    14341 tgaaaattcc ccccgaatct tgatagagcg gaaaagattt tccccatcat aataagactc
    14401 aattcgttct ttcaattcct tgtctgtcat ctcaaagcgc tggcggaaaa tgacctctgc
    14461 ctgatgcggt accactgcag cgtaaggaat aagggcatct ggtgacactt ccacaatttc
    14521 tggctggtct cctgaccctt tggcctgata agccttgcca tccaagacaa tcaattcccc
    14581 atcaatggaa tccaaggttc ccaaaccaag gtcaccatgt tctagcaatt ctcctactgt
    14641 catagtacca ccataaaggc cagccatcaa ggctccaaga gtattgtatt gaaataattt
    14701 cactggttcc tgcacgttct tatccattca ctttcttgtc tgttattcta taaatcttac
    14761 tcctaagtat accacatttg cccctagatg tgaacgagag aaacgctcta gacattgcca
    14821 agaaggaaaa acagggtaca atgtaacaaa atcaagggag gtctggaatg aagaaacaaa
    14881 gcaagtacaa agaggtcgtt tcctatctga aaaatggtat cgagtctgga cgatttccga
    14941 cgggtagcct gagattttga cagaaacaaa acttgcacta gcacaacaac ccctaaggaa
    15001 cacacttccc taggggtcgc tttttattta actaaatcat tatttatttt ttgttcctag
    15061 taaacataaa tattgtatta ataattgcaa aaataaatgc aaacaaaagg attttccaaa
    15121 ggataaattt ttgtaacact aaatatgcat atacaaatcc aatcaaaaag ctaataatcc
    15181 catcttttat taaaaagttt ttatcacgca ttattccaga ccacactgaa ctgcccaaat
    15241 agccaactga ccagcaatga tataaatatt tgttttaagt ccattagctt taacaaatct
    15301 tagtaccact ttagctaatt ctgaccaagc ctttttctgc gcatacttaa caattagcga
    15361 aacattgatc atagcaaaaa attcatctcg tatttttcct gctatacatc ctcccatctc
    15421 atcccaaggg actctgtcat agggattatt aatattagtt tctaattcat tttccgcaag
    15481 agcaatatct ttttgagaaa agtttttata aacatattca gtaaaatttt tttcattaac
    15541 tccatttcta aacatttgtt caagaacatt ggctacatca tcgatttgtt tttgttcttg
    15601 ggtactaatt tcagaaactt ccgtagtagt tacatcatca gcaaatactc taacagaagc
    15661 tatagaagga gacataatag aaaatagtga taatacaaca agagctgaag ttacaatttt
    15721 tttaaatttc ataaaaaaca ctcctttcaa gtcacaaata tatattactg ataaaataac
    15781 ttgattttct gatttaaaac tcctttctaa caagttattc gtatgctttt attttttagt
    15841 tctattatac cacaacaaga aaacgatttc aagcattttc ctaaaaatat gtacaagtaa
    15901 tatgtacaag taataagggg aaattagcat aaaaactttt taaaacaaat caaccccaga
    15961 taaaaataca catgttgttt taaagacaaa aaagggtacg aaaaactgtc acatctgcat
    16021 ttgattgctc tttgatttca aaaaagtatt aaaaatggga gtataccaca tttgccccta
    16081 gatgtgaacg agagaaacgc tctagacatt gccaagaagg aaaaaaaagg gtacaatgta
    16141 acaaaatcaa gggaggtctg gaatgaagaa acaaagcaag tacaaagagg tcgtttccta
    16201 tctgaaaaat ggtatcgagt ctggacgatt tccgacgggt agtcgcctgc cttctatccg
    16261 tcaactgagc cttgactttc actgcagcaa ggacaccatt caacgagccc tgctggaatt
    16321 acggcacgaa caatatctct atgccaagcc tcagagtggc tactatgtat tagaacaagg
    16381 gcaacatcaa gacctagaaa tcgaggttac cgacgaacat gccagtgcct atgacgattt
    16441 ccgactctgt gtcaatgaaa ccttgattgg ccgagaaaac tacctcttca actactatga
    16501 caatcaagaa ggattagaag acctaagaca gtccattcac aaactcctct ttgagcaagc
    16561 tctctactgc aaggctaacc aactagtact gacttctgga acccaacaag ccttgtttat
    16621 cctctctcaa atatcctttc ctagacaagc caaggaaatc ttggtggaac agccaaccta
    16681 ccatcggatg aatcgcctct tgattgcaca ggggctggac tatcaaacga ttgaacgagg
    16741 cattgatggg attgacttgg aggagctgga aggccacttc aaaacaggaa aaattaaatt
    16801 tttctacacc attcctagat ttcactatcc tctgggacat tcctattctg agcaggacaa
    16861 acgatctatt cttaacttag ctgccaagta tgatgtctat atcgtagagg acgattatct
    16921 gggtgatttg gactccaaga agggccaaac cttccactat cttgatacag aggagcgtgt
    16981 catttatatc aagtccttct cgaccagcct ttttcctgcc cttcgtatta cagcactcat
    17041 tcttccaaat gctatcaaag aagcatttgt ggcctacaaa aatatcctag actacgacag
    17101 caacctcatt atgcaaaagg ccctgtcact ctatattgac agtcaattgt ttgaaaaaaa
    17161 tcgtttggct cgcttgacca atcatgaatc ttaccaaaaa caaatcgagg aaaggataac
    17221 taaaacacct tgtccccttc ctcattatcc cctacacgat ggtttattgc tagacctgag
    17281 acagtatcct aaaatcgcca gtctcaaaca cagtcaactg ggcttggact tctttgaaga
    17341 ggcctattta agcacctgtc cttatcaatt tgccaaggtg tccctagaca atctggaaaa
    17401 tgttttaaac tatttaaaag cagaattgga atgacatcca actctgcttt ttcttattct
    17461 tcaacttcag ttaaacttgc tgctttttca agatagcttt ggtaagttcc ttcatcctta
    17521 agtttttgga tgaccttgtc taccacttct ttcaaatcat cactattttt tctaagagca
    17581 acggcattgg cgtcgccgtc cttcatcttc aagctgacag ttgcgacagc taagccagcg
    17641 tttttagcag cataactaag tgcaacaggc tcatccatat gaacagcatc tacttttcca
    17701 gcctgcaatt cattgactgc ttcacccata ttagttaggg aagttaattg agcttttggc
    17761 aattgttcct tgaccattga ttctggaaca gtcccttttt gggctgcaat attagcactt
    17821 tctaggctag ttaaatcctt gtatttttcc acatcagcct tacgaaccaa gaaactaatc
    17881 ttgttttcat agtatgggat tgaaaaatca aagacttctt ttctctcgtc agtagcacta
    17941 attcctgcaa ctgctaggtc agccttacca gtttgaagac tggtcaaaac attatcaaaa
    18001 ctcatgcttg agatttccaa cttaacccca agttcatcag cgatagcctg agccatgtcg
    18061 atgtctgcac cgactacctg gttctttcca tcaaccaatg attgaaattc aaagggtgca
    18121 tagtcaggac tggttgccac aactaatttc cccttttgct taatggcctc aacagctgac
    18181 tgagaaccat tagaacctga ctggcaagct actaagaaga aacttgcaag aaaattacat
    18241 aaaacaaata tccatttttt tgatttcata aataaacaac ctctctgtta attttgtata
    18301 attataacga tatccaagtt acttgtcaag tgttttttaa atttttatct caaaaatatt
    18361 ttttcgttca aaaaaaggag ccatcagttg atttcaagct cctttttata cagaattaaa
    18421 ctattttata gttcgacaat cttacctgtt tcaaagtaga caacccattc acagatattt
    18481 ttagcatagt caccgatacg ctccaagtag gaaataactt ggaaataatc acgacccgta
    18541 acaatggctt ctggattttt cttaatctct tcagtcgcaa ggtcacggat agtttcaaaa
    18601 tagtggttaa tttgctcatc catggaggcc acccggtatg cgtcgtcaac agaaccatta
    18661 agataaagat caagtgctgc ttcaacaacg cttttaactt cacgtcccat ttttttaatt
    18721 tcttcctcta cagctggaat gcgctcttcc cccttcatac ggatggttgc ctgagcaatg
    18781 gctacagcgt gatcccccat acgctccaca tctgatacag ccttaaggac agtcaagact
    18841 gtacgcaaat cttgagagac tggttgttgg agtgcgatca tttcaaatga tttcttttcc
    18901 agtttcactt cgtattcatt tacttctgca tcatcttcga tgacctcttt tgccaggtca
    18961 cggtcatgcg tgacaaaagc acgtaccgta cgattgattt gtgagagcac ttcttgtccc
    19021 atagcgtaga actggttatg taatttctct aaatcttctt caaattgaga tcgtaacatc
    19081 tttcatctcc ttatccaaat tttcctgtaa tatagtcttc cgtttccttg tgttggggat
    19141 taaggaacat ctgcttggta tcattaaatt caatcaaatc tccatctagg aaaaatcctg
    19201 tcttatcaga gatacgtgaa gcttgctgca tggaacgggt taccagaagc atggtgtact
    19261 tgtcttttag accatacaag gtttcctcaa ttttaccagc tgaaatcgga tccaaagccg
    19321 aagttggctc atccaagagg atgattttag gactagttgc caagacacgg gccacgcaga
    19381 cacgctgctg ttgaccacct gacaatccaa tagctgaatc atatagacga tccttgacct
    19441 catcccagat agaggcacct tgcaaggctt tttctacggc ttcatccaga acctgcttat
    19501 ccttaattcc attgatacga agcccgtaga caacattctc atagatagtc atagggaaag
    19561 gattaggttg ttggaaaacc attccgattt ccttacgtaa ttcaaccgta tctgtacgcg
    19621 gactgtagat gttgtgacca ttgtacacca cggatccagt tgtggtcacc tctggattga
    19681 gatctcccat gcggttgaga gacttgagga gggttgactt ccctgatcca gatggaccaa
    19741 tcaaggctgt aatttcctta ggttggaaag atagggaaac actattcaaa gccttctttt
    19801 tattataata aacggacagg tctgatacct gtaaaatcgc atctgtcata cggtttcctt
    19861 tctaaccaaa gtgaccagat acatagtcat tggtggactg tagcttggca ttttggaaaa
    19921 tagttgcagt cttgtcatac tcaatcaaat cacccaagta aaagaagcct gtatagtcac
    19981 ttgcacgagc agcctgctgc atattatgcg ttacaatgat gatggtaaag tttttcttga
    20041 gctcaaacat ggtctcttct agttgcatgg tcgcaatcgg atccaaggct gaggctggct
    20101 catccattaa gaggatatct ggcttaacag agatggcacg agcgatacag agacgttgtt
    20161 gctgaccacc tgataaggtc aaggctgact tgtggagatc gtctttaacc tgatcccaaa
    20221 gggcagcctg acgaagggag gtttctacga tttcatctag gacttgctta tccttaactc
    20281 cagcacgttc atgcgcaaag gtaatattac ggtaaattga cttagcaaat ggattggggc
    20341 gttgaaaaac cattccaatg tgtttacgca tttcataaac gttgatttct ggacggttga
    20401 catcaattcc acgatagaga atctgcccag ttactttagc aatatcaatg gtatcattca
    20461 tgcgattgag actgcgtaag taggtagatt tccccgatcc cgacggacca atcaaagctg
    20521 taattttatt tctttcaaat tgcatatcaa tccccttaat ggattcattt ttaccatagt
    20581 aaacatggac atccttagta gaaagggcta ctttttcttc aggaaaggta aggatatgct
    20641 tctcatccca gttatatgtt gacatggctt ctcctttagg cagcggttaa tttcttgtgt
    20701 agatagcttc cgaacttacg agctccaaag ttaaaaatca ggataaagat caggagcaca
    20761 gcggcagaac ctgctgatac aatggttcca tctggaatag tgccttcact attgactttc
    20821 cagatatgga cagccaaggt ttctgcttga cggaagatag agatggggct agtcacactg
    20881 aggatattcc agttagacca gtcaagagct ggcgccgatt gccctgctgt atagatcaga
    20941 gctgcagctt cgccaaagat acgaccagat gccaaaacga cacccgttac aatacctgga
    21001 agcgcttctg gaataacaac atgaaccact gtctcccagc gagaaatccc aagagccaga
    21061 ccagcctcac gttgggtatg gtgaacgtgt ttcaaactat cctctacatt acgcgtcatc
    21121 tgaggcaagt taaagactgt caaggccaag gcacctgaaa tgattgaaaa tccatactca
    21181 aactggacta caaagatcaa gtaaccaaag agacccacca ccactgatgg taaagaggac
    21241 aagatttcaa tacaagtccg cacaaagttg gtaacaggac cttttttagc atattcagcc
    21301 aagtaaatcc cagctcccat agaaagaggt acagaaataa tcaaggtaat gaccaatagg
    21361 aaaaaggaat tgtaaagctg aatgccaatc ccaccacctg cttgaaaagc agaagacctt
    21421 ccagtcaaga aagaccaaga gatatggggc aagccccgaa ccaagatata gagaatcaag
    21481 gaagccaaga ttgtcacaat gatgctagca atcgtataga ggacagctgt tgcaagttta
    21541 tctaatttct tagcgcgcat aatttttctt tcctctttct ttcgtaatca atttaatcac
    21601 actgttaaaa actaaactca tcaagagcag taccaaggcc agtgaccaga gaacattatt
    21661 atttacagtt cccatgacag tgttcccaat tcccatagtt aatatagaag ttaaagttgc
    21721 agctggtgtg gtcaaggaag ttgggataac agctgagttt ccgacaacca tctggatagc
    21781 tagagcctca ccaaaggcac gcgccatccc aaagaccact gcagtgaaaa taccagaacg
    21841 ggccgccttc aagatcacac gccagatagt ctgccagcga gtggctccca tagcgaaact
    21901 ggcttcacga taataacgag gaaccgcacg caagctatcc gttgtcataa aggttacggt
    21961 cggcaaaatc atgacaaaga ggacggaaat ccctgacaaa atcccaaaac cagtcccacc
    22021 aaagacactg cgaacaaagg gaacgacgac ttgcaagcca ataaatccgt acactactga
    22081 aggaatccca accaggagtt caatagctgg ttgcaaaatc ttcgcccctt ttggtgatac
    22141 ttcggtcata aaaactgctg caccaatagc aaagggtgtt gcgataaggg ctgagagaat
    22201 ggtaacgata aaggaaccca aaatcatagg aagggcacca aattctttac tagaaggatt
    22261 ccaagttcct cccaaaagaa agtcaaagat attcacacca ttgacaaaga aggtcgacaa
    22321 gcctttttgc gctacgaaaa ccaaaatcat ggccacaagg atgactatca aagaaagaca
    22381 ggcaaaggtc aaaccttttc ctaatttctc cagacgagaa ttctttgatg gaagcaacat
    22441 tttcttagct aattcttctt gattcattat tgtctccctt ccaacactgt cacagttccg
    22501 gcagcatctt tttcaacctt catttcctta atcggaatat acttcaatcc tttgacaatc
    22561 ccttcttggg tctcatccga gagaacaaaa ttgagaaatt ctgcagccaa ctcattgggc
    22621 tgccccaatg tatacatatg ctcataagac cacaagggcc aattattgct acttatattt
    22681 tctggactta agtcatagcc attcaacttc atgcttttga ccgaatcatc tatataggta
    22741 agagataaat aagagatagc tcctggactt tttgatacga ttgattttac cgctccattt
    22801 gaatcctgct cctgactttg catggcagac tgaccttcca taatgacagt atcaaaggta
    22861 gcacgagagc cagagccggc tgcccgattg ataacagaga tgggtaagtc cttaccacca
    22921 acctctttcc aattggttac ctcacctatg aagatttgac gaagttgctc tgtcgttagg
    22981 ttatcaacat caacctcctt attgacaatc agagccaagc cagctaccgc gaccttgtgg
    23041 tcaacaagag cagaagcatc aattccgtct ttttcctcag caaatacatc tgagtttcct
    23101 atatcaactg ccccagactg aacctgggac aagcctgtac cagaacctcc cccttggaca
    23161 ttgaccgttt ttccaacatg gatcgtgcca aattcatctg ccgctacttc aaccaagggt
    23221 tgcaaggcag ttgagccaac agccgttatg gattctccac gatcaatcca gctagcacag
    23281 cctactaaac aagccgtcag ccaaaaagcg ataagagaca gagcaagctt ttttcttttt
    23341 ttcactgttt ttctcctcga aaataattat gaatactgtg aattttttaa gtagttcttt
    23401 atgagttgac gcatgaattc ttaccaaatt tctgcgcaat tgattattta tataatatag
    23461 gctatattac tctttcctaa cctccttttt tcatatgtgg ataaaatctc ttgtctatcc
    23521 cttcccccat tgtcacccat tatagtcatt tcgtgtctct ttttcccctt tttaatgcaa
    23581 gggaaattac tcttcttaga tgataatcca aaagctagaa aggtatctca aacctctcta
    23641 ctctcccaga ctagtttaca actaaaagga aaagattcta ttttatgaga aatctagttt
    23701 acaagcggta agaacgctaa taactaaact tcttgtactc tttgaaaatc tcttcaaagc
    23761 agtgttttga gctatctatg gctagcttcc tagtttgctc tttgattttc atcgagtagt
    23821 aaaactacat gtgatggcaa tcaagatatc aagaatcatc ctactaaaaa aatccatact
    23881 ttcactataa catagaataa gatatttgac tagcattttc atttgaatct gaggcctttt
    23941 ggaaaataat ttttcaaaac atttccagta acctttgcaa agcccaagcc attgccttta
    24001 accaaaactt ggtaccaacc atttggcaga ctttctgcca gctgaacggt ttctccagcc
    24061 gcatacttga caaacgcttc ttggccaatt tcaaccgact gttcgacctg actcggtttc
    24121 aaggctaaac caagagcgaa actgggctca aagcgtttct tcttaaaagt acccagatgc
    24181 agtccattgc gagcaatctt gagcttccct aaatctggca aaagttctgg caagagataa
    24241 agctggtctc caaaaatctg caagataccc ggtagattga ccttcaaatg gttttgggca
    24301 aattcctgcc acaaggcaac ttgttcacgg ctgaggttac tcttacttgc cttaaattta
    24361 ggagctggat tgttaccctt aaactgtaga tgggcaacaa actgaccctc tcccttaaac
    24421 tgatgagggt acatccgagc cgtttctggc aggtcaatac cagctaccat tccattgata
    24481 tgctctactg gcaacaagtc aaaatcatac tcttccagca accaattgac aatctcttcg
    24541 ttttcctcgg gtgcccaggt acaggtcgaa taaaccagac gaccaccttc agctaacatg
    24601 gtcactgcat cctccagaat ttctctttgc aagctagcac attgactcgg ataatctaag
    24661 ctccaatagt ccatagcatc aggttgctta cgaaacattc cttcaccaga gcaaggggca
    24721 tcaagaacga ttaagtcaaa atagccttta aagaccttga ccaagcggtc ggcagattca
    24781 ttggtcacca cgacatttgt cgctccaaaa cgctccatgt tttcaaccaa aatcttagcc
    24841 cgtttgcttg aaatttcatt ggaaacaagt agcccctccc ctgctagata ggctgccagt
    24901 tgagttgatt tgccccccgg tgcagcagcc aagtccaaga ccttcatacc aggactgggt
    24961 tgggctactt gagccaccat ttgagcagca ggttcttgcg aataaactaa acctgtagca
    25021 tgctcaggcg atttccctga aaccttccca tagtggcccc aaggggtttg agtaatggca
    25081 tcagaaaagg aaagttgctc ttcttttaag ggattgaccc gaaaggccga aaccgcttcc
    25141 tcctcaaaag aggcaagaaa atctcttgcc tcatctccta gtatttcttt atatttttca
    25201 acaaatcctt ctggaaattt catttaagtt cttttccttt cgtaaatata ggactgaatt
    25261 tcctcctgca tctcaagagg caccatcatg accggctgtc tggtttgaaa atcaggagct
    25321 tcaccaaaaa gggtcacaac ccgatagccc agactttccc ctaaaatact agctgcggca
    25381 taatcccatg gttgcagata ggtgagatag gtcaacaaat gccctgacaa aatcttggca
    25441 aaactaatgg ccgcacttcc atagacacga acaccaagaa ccgctcggct caaatcagcc
    25501 agcccccatt cattggtttc cagcatacca ctattccctg caatgagaaa atctccaagt
    25561 ggtttagttt taaaaggagc taggggccta tcatttagac aaactggaaa ttccccacca
    25621 ccgtggtaac aatccccttt gaccacatca taaatcagac caaactgtcc ctgaccattt
    25681 tcaaaataag ccatcataac agcaaaatct tcctgctggg ctacaaaatt attggtacca
    25741 tcaatgggat caatgaccca aaccttgccc tcttgaaccg aggctcgcag acaaccttct
    25801 tcagcacaaa tcttatcctc aggataacgg gacaaaatct caccaaccaa gagttcctga
    25861 acttctttgt ccagtctggt caccaaatct gttggagagg acttggtttc aacacgcaag
    25921 tcttcctgca tatggtcaag aatgtactgg cctgctttct taacaagctc tttagcaaat
    25981 tcaaatttac tttccaagag aaatctttcc ttcccctttt tctttggcag cctgaactgc
    26041 tcggtaaagt gaatagccac taaccgtttc aaattctcgt cccaaacgtt tctcttcgct
    26101 cttgcttggc acgaccgctt tgaatccctt ataggagtcc agtaactttt tagcctctac
    26161 tttgccttca taggcagctt caacatcatt aaaaaaagaa agcactgaag caagttcttc
    26221 agtgctccac gacaaatcta gtgggtaact atactgtttg ttcattaact aataccagct
    26281 ctcattcttg cttcttttag ttcttgctta cgataactac gagggagaaa agcacgaatc
    26341 tcatcttcat taaaaccgat ttgcatacgc ttggcatcaa taataattgg acgacgcaaa
    26401 agactaggat actgctcaat caaatgaagc aattccgata ccgaaatact ctctacatca
    26461 atattcaatt tttgaaaaat ttttgaacga gttgaaatga tgtcatcagt accattttcg
    26521 gtcaaggaaa ggatgtgttg caattctttt cttgttaaag gactggtcat aatattgtgt
    26581 tccacaaagg gaaccttatg tttttctaac caggccttag ccttacgaca tgatgtacag
    26641 ctcggtgata gaaatagtgt aatcatgctt ttctcttctt atctatactt tgctacttct
    26701 attatacaaa aaaataaagc gcttgactag ggatttttag aaaaaaagcc tattttttca
    26761 agaaaaatag gctttttgcg aacgattgac acaattggat ttggttaatt cactcttaac
    26821 gatggtttta aacgatatat atttttatat atgtaaatta aaaacatctt tcctttcact
    26881 tcctacgact tttcagatac agatagccaa agaagttttc atagagggca aaaaagagga
    26941 ggaaggcatg aagaaagaag gtctctggca aaatcataat aacaggatcc ttggctggat
    27001 caaaaagcca ggtatcatct cccacaaaga gaatttgatg gaaaagagta aagaattggt
    27061 caaaaccaat caaaactccc ccaagtccaa tcatcacagg taagactact agagccagga
    27121 gactttttcg ataaagagac aaaaagtcct ttttcacaat cctattgaca aagacataga
    27181 aacttggcag tgtcactaga gctactagct gaaccaaatg aaagagattc ttgaccactg
    27241 cgaaatggtg cagaccagct gctgacgaac gaaaatcagg catctgtaag acctgactaa
    27301 aaggattggt cagataattc atcaagatat gaaaattgta ttgaatggtt tctggtttta
    27361 gatagactcg attcgttaag tttagccact gaatctccat aggatagaaa atccaagcca
    27421 gataaatggt cagaaggatt gagagggaga ggagaaagag catagagccc caaaaggtca
    27481 atttagtttt catcaaaatc ccactccgca aggctagaaa ccacatgtgt cggtgcgatt
    27541 ggcaggccag ctacttcttc tgccttagta aaacctgtcg tcaccaagag cgttggaatg
    27601 ccattgtcaa tcccagcccg gatatcagtc aaataattgt ccccaaccat gattaactct
    27661 tcacgttcca aacctaagtg ctcaaccgcc ttgtccataa tgatggcatt tggttttccg
    27721 atataaaccg gcttcactcg tgtcgctact tcaagcagcg taatcagtga gccagcacct
    27781 ggcaaaagac cacgttccgt cgggatgttg aggtcaggat tggttccgat aaaatgggca
    27841 cccttttgaa tagcaagagt tgctgtggca aatttttcat agtcgacttg ccaatccaga
    27901 ccaactacca cgtaggcagg gttttccttg tcttccacat aaccagccgc cttgatggct
    27961 tccttgagtc ctgcttctcc gacgacatag acagtctttt caagccccaa atcattcata
    28021 tagtcgatgg ttgccaaagt cgctgtgtag acagtcgata gaggcgtatc gatattaaaa
    28081 ttctgagcca acatctcctt aacactctct ggagtgcggg ttgtattgtt ggttacaaag
    28141 agatagggaa tgtcccgctt ttgcaattca tgaacaaaag tctctccagc agggattcgg
    28201 tctttcccct tataaatggt tccgtctaaa tcaattaaat agcctttata tttcatctat
    28261 ttctccctaa acctttttta tttcttgcca agtaatgatt gcttgggcat tgataacccc
    28321 atcacttgta atttcatgct tgctttccag tccagtccgt tcaacagccg atgtaatcac
    28381 cccacctggt cgaacttcct tgacatactt gaggttgatt ttcttgggaa tatagtgggt
    28441 caaaaaatcc gctcccatga cctcaaaaat ccagtccaag tatttactgt tattgacatg
    28501 accattcata tccaagtcgt aaaaacgaac atggtaatcc ttgctgatcg gctcttccaa
    28561 ggattcatac ttcggtccac ggataagttt tttatcaaaa tcagactggt aaggagccac
    28621 aatctcaggt tcaacagcat ggacttttcg actgtcgcgg tccatgagaa caaaggtcgc
    28681 catcatatgg atgagctcct gccccgcttc attataaata gtaaagcgac ggtagcaaaa
    28741 aagtcgattg tagctcaagg cttccgtttc gatggtaatt tcttccgcaa aacgaggcaa
    28801 acgaaccacc tcaatatcat attctgcgat aatccagacc agattatagt cttccaaaat
    28861 ggccttatca ctaactccca gttcaatcga ttgcatccct gaaacttgca gtgacagcaa
    28921 aatcacatct ggaagtttga tatgaccgtt catatcagcc atatcaaaag gaattttcat
    28981 tttcatttga taagttaagc acatgatcct actccaaaat aaatcgttct gctacagtat
    29041 ctcccaaaaa gagacctctc tttgtcatgc gaacgtggtc accctcaatc tgcatgaggc
    29101 cttgttgaac caaatctctg acaatttctc cataaagtcc agcaaaagac tgtccaaatt
    29161 tttcctcaaa tcgcgccatg gaaaccccgg atttcttgcg gagtcccaag aacatttctt
    29221 cttccatttg ctccttttga ctcaggtgat cttctgtaat acaagcattg ccttcctcaa
    29281 ccgcactgag ataatgacga atgggaccat gatttttata gcgtactcca ttgacataac
    29341 cagatgcccc tgcaccaata ccatagtatt cagcattgtc ccagtacatg agattgtgac
    29401 gactttcaaa gccgggtttg gagaaattag aaatctcata atgctcaaaa cccgctcgct
    29461 ccagctctgc aatgatgtac tcaaacatct ccgcttctag ttcctcctta ggcagaggca
    29521 atttcccacg tcgcatccgg ttcataaaga ccgtatggtt ttctaaaatc aaactataca
    29581 aactcatgtg gggaatatcc agtccaatgg ctttagccac attttccttt acttgctcca
    29641 tggtctgacc aggcagagca taaatcaaat caatggagat gttgtcaaaa ccagccagtt
    29701 tcaggcgatc gatattttca taaatatcct tctccaaatg actgcgccca atctttttca
    29761 acatcttatc atcaaaggtc tggacaccta gcgaaacacg attgacagcc gaatttttca
    29821 aaacagctat cttatccgca tccaaatcgc ctggattggc ttcaatggtc aactcttcca
    29881 agacagacaa gtccaagttt ttagtcaagc cattcagtaa cacctccagt tgcggagccg
    29941 acagggctgt cggtgttcca ccaccgatat aaagggttga caacttttca atatcataag
    30001 aacgaaactc ttccagcaga tgctctaaat agctgtcgac tggctgattt ttgatgaaga
    30061 cctttgaaaa atcacaataa taacaaatct gggtacaaaa tgggatgtgc acataggctg
    30121 acgttggttt tttctgcata gtaattatta taccacaaag actagattcc agataaaaat
    30181 caccatcccc agatacatag tccgtccgga gatggtgatg gtttattctt ctgttatatc
    30241 aatcacaatc tcttctgagt catcaagagc ttcggctttt tcttgccatt gctccttgag
    30301 attatttaat tgattttttg atgcttctgt cgcttgaaaa gcataggatt tagcttgagc
    30361 aagtatactg tccacagtga tttcacctga ctcaacctgt tcttttgttt tcagaacaaa
    30421 atctgtagcc tgctccttaa cttctgtcag tttttcacag acttgctcct tggcatactc
    30481 cggatcttct ctcaaatcat ctagaaaatc ttgagcctga ctgcaaactt gtttgccctt
    30541 atcacttgtt aaaaacaagg caagagctgc acctgaaacg gttcctaaaa ggattgagga
    30601 taatttaccc ataaggattc tcctttttta ttttttgaaa aatttacttg caagacgaag
    30661 agctgacaga cttgcaccag tcttgagtgt ttttgaacca gctgatgaag ctttcttgct
    30721 caagacacgc gcatggtcat tgaggtctga aacagataga gataaatctg caacagcact
    30781 gaagagtgga tcaatcgtag ccaccttgac attgatatca tctgccaaga cattgacctt
    30841 agccaacaac tcattggtgt gatgcaaggt cacatccaca tctgaagtca aggttttaat
    30901 cgtcttttct gtttcatcga tgacacgacc aagcttttgt acagtaatga tcagatagac
    30961 caaaaagaca atcaaagcta gggcaacaag aatatatgca acttctaaca tttagttttc
    31021 ctcctctgta atatagtaag gggccttctt tcgattttga taaataacga tcattatacc
    31081 gagaccgata aagacaactg acagccattg ggacactcga aggctgaaga acatgagact
    31141 atctgttcgc ataccttcga tgaccatacg accgaaacca taccaaatca agtaaaaggc
    31201 cgtgatatga cctcgtctga gactcttcca tttccgtcta aaaatcagaa tcaaggcaaa
    31261 gccaagcaga ttccatagag actcataaag gaaagtcggt tgacggtagc tcccctcaat
    31321 atacatctgg tcacggataa agccaggtag ataatccaga ttatccactg ttgcaccata
    31381 agcttcttgg ttaaagaaat taccccaacg ccccaaactt tgagcaatca taacgctagg
    31441 cgccgcaata tctagaaaat cccaagtatt gatgagttta cggtcagcaa agatatagag
    31501 cacaagagcc ccagttatca aaccaccgta aatggccaaa ccaccattcc aaatggcaaa
    31561 aatctctcct aaattctgac tatagtaatc aaatcggaaa ataacatagt agagacgagc
    31621 tcctaaaata gccaagggaa aggctactaa gataaaatct aaaatatcgt ctggtatgat
    31681 cttctttcta ggtgcttctt tcatggtcaa ataaaccgca agaatcaagc ctgtcacaat
    31741 acataaggca taccaacgaa tggctagggg tcctagttga atagcaattg gatcaagcat
    31801 tttgcacctc atttcgagct atgagacttg tcagtcgttc gtcgaacaaa cgggtagcat
    31861 caaagcccat ttccttggca cgataattca tggcagctgc ctcaatcaca acagagatat
    31921 tacgacctgt tttaactgga atacgaatac gaggaatggc tacgccagaa acttcaagtt
    31981 cctctgcatt gtttccaaga cgatcaaagg tcttatgcgt atcgtaattt tccaaataga
    32041 cagcaagctg aacctgtgaa gaatccttga cagcactcgc accgtagaga ctcataacat
    32101 cgataatacc aaccccacga atttcaatca agtgtttcaa aatttcagct ggttcacccc
    32161 agagagtaat ctcatccttg gcaaagatat cgacacggtc atcggctacc aaacggtgac
    32221 cacgtttgac aagctcaaga cctgtctcgc tcttaccaat tccactatct ccctgaatca
    32281 agacgcccat cccataaata tccatcaaga caccgtgcac actggtacgt tctgccaaac
    32341 gagaatccag atagctagat aactctccag ataaacgact ggtagctgca cggctggtta
    32401 aaatagcaat cttacattct ctagcagcct ttaacatctc ctctggaacc accaaaccac
    32461 gggcaacaat gactgctggt gtctcaggta gaaacatttt tttcaaaact tcataacggc
    32521 tgttggaagg catgctgatc agataagacc actccttcat ccccaaaagt tgaatccgct
    32581 ctggtgtata gtagtcaaaa tagcctgtca tttcaagacc aggtcgcgta atatccgctg
    32641 tattgatttc cttttcaagc aattctggtt caccatagac aatatctagt ctaagctttt
    32701 caatcacttc ttttactaaa accgacatca tttcctcctt caaatgaatt cttctctcta
    32761 ttatatcaaa ttgtaggagg aagtttcaga tttttgcagg ctttggagta tttatttaaa
    32821 agaaaaagga ctagatttct ctagcctttc atttcaatta gaatttttta cgtttacgag
    32881 ctacttctga tttacgttta cgttttacag aaggtttttc atagaattca cgtttgcgtg
    32941 tttcttgaag agtaccagct ttagtaaccg cacgtttgaa acggcgaagt gcgtcgtcaa
    33001 gagattcatt cttacgtact actgttttag acattttttt cactcccttc aagttcaata
    33061 tctatttcat tctacacgta aaaggaataa ttgtcaagca aaaatgcggt ttaattttga
    33121 ttttttcttc catttataca agagttgaaa gcgttcaata gaacattgct tttttatttt
    33181 tcgagtaagc taagcgcttc agcatctgcg atgatggtta catcagggtg attttggagg
    33241 ctacttgcag gtaggttctc agtcactggg ccagatactg ttccggcaat ggcttctgct
    33301 ttcgactcac cataagcaaa aagaataata gacttggcat ccaaaatgtt tttaatcccc
    33361 attgaaatag cttgggttgg gacgtcttca atcttggcaa agaagcgagc attggcttcg
    33421 atagtagact ggtcaagttc tactagatgc gtttgactgt caaatggagt accaggctca
    33481 ttaaagccga tatgcccatt gcgaccgatt cccaagattt ggaggtcaac tggatggtca
    33541 gccaaaattt ggttgtagcg ttcaacttca gcttcagcat tgtccttaac accacgaggc
    33601 aagaaacttt ctttaaatgg tttttggttg aacaagtttt cttgcatgaa gtaacgataa
    33661 gactgtggat tgtccccatc aaggcccaca tactcatcaa ggttgacact ggttagattt
    33721 gaaaaatcaa ggtcactctc aacaatttcc ttgtaaaatt caagtgggct acttcctgtc
    33781 gcaagtccta gagtttgagc tccattagcc aatttttcct tcaaaatctc aaaagcaact
    33841 tttccacctt gaacttggtt ttcaacttta ataactttca tcttttcatc ctccatttct
    33901 gtctatattt attatatggt atagaccaat ttttgtcaag tgaaaacgat ttaatttcta
    33961 aaaaaagagc gtccaaactt gaaacgtgtt ataatggata ggattagaac ttagaaagaa
    34021 tgaacaaata tatgaataca gctgattttg atttccactt gccagaggaa ttgattgccc
    34081 aaacgcccct tgaaaaacgt gatgcctcca aactcctcat cgtcaaccgt gagacaggag
    34141 aaatgcaaga taaacatttc cactctatta ttgatatgct ggaacctggt gatgcccttg
    34201 tcatgaacga cacccgagtt ctccctgccc gcctctatgg tcaaaaagtg gagacaggag
    34261 gtcatgtgga acttctcctc cttaagaaca ctagtggaga cgagtgggaa gttctggcta
    34321 aacctgccaa acgcctcaag gtcggtactc gtatcagctt tggtgatggc cgcctcagcg
    34381 ctgtcgttac agaagaattg acccacgggg gacgcattgt ccgctttgaa taccaaggaa
    34441 ttttcctaga agtcttggaa agtctgggag aaatgcctct gccaccttat atccacgaaa
    34501 aattagatga ccgtgaacgt tatcaaaccg tctacgccaa ggaaagcggc tctgctgcag
    34561 caccgactgc tggtcttcac ttcaccaaag aactgctggc agaaatccaa gctaagggtg
    34621 ttcatctagt ctatctgact ctccatgtcg gactcggaac ctttagacct gtttctgtgg
    34681 ataatctgga cgaacacgaa atgcactcag agttctatca actttctgag gaagctgctg
    34741 ccacccttcg ctctgtcaaa gaaaatggtg gtcgcgtcat cgctgtcgga accacttcta
    34801 tccgcacctt ggaaactatt ggttccaagt ttgatgggca aatccaagca gattctggtt
    34861 ggaccaatat ctttatcaaa cctgggtatg agtggaagat cgtggatgcc ttctcaacca
    34921 acttccatct gccaaaatca actctggtca tgttggtttc tgcctttgca ggccgtgaat
    34981 tagtcttaga tgcctaccac catgccatcc aagaacacta ccgcttcttc agttttggtg
    35041 acgccatgtt tatttattga gaaagaattt ctctaattct tctaatacca ataaatcgct
    35101 aagatattat ttcaaagaac atctacaatt gaaactctag ctagctgtag aagacgccta
    35161 gtacattgaa attaaaatgc ttccccctag cttcgaaaat attgccatag attgcgttga
    35221 ctctccaaat tgattcatct atattttatt tcagcttcct atattttctt cgctgtttgt
    35281 aaatcaaaat gcaagacaca tgagtagcac catatttgtt actcttatct gtcctctcaa
    35341 gagactatta tgagttattt cagaatcatt cactactttg accctgactc tccttagtct
    35401 caaaatcaaa gacttatact cttcaaaaat ctcttcaaac cgcgtcaacg tcaccttgga
    35461 ttatatatgt gactgacttc gtcagttcta tctacaacct caaagcagta ctttgagcaa
    35521 cctgcgacta gttttctagt ttgctctttg attttcattg agtattaaac aaaaagtgaa
    35581 caaatctgaa ttctaatgta cagaagacta ggcttgttca cttttttata gtcgctataa
    35641 gatgacctta tctatagctt tttatatata attatatatt cagacatact attatcaatt
    35701 ttgtcgcagg gaggaatctg ttaacgcacc cattcaccat tatcattgac tctatagcca
    35761 tctatacttg tattgaccgc taactcaccc gatgcattta cataatacca tttaccacca
    35821 acttggaacc attgattgac tttcatagaa ccgttgctgt tgaggtagta ccatgaacca
    35881 ttaacttgta cccaacctgt tgccatggaa ccatcagtat tataaaaata ccacatacca
    35941 ttttcttgtt tccagtctgt tgttggagca actgctttag ctggttctac tgctacatct
    36001 gttccttggt tagatgtaac agatacagga tacgaaggaa tagatgattg ctcaggaaca
    36061 acaacttttt caggttctct cgtccctctc cttatacgtc tttttaccat ctctttagta
    36121 atttgacgag aagtagtttc ttcaattatt ccatcacgtt catctacagt atagattgta
    36181 gtaagagtaa tttaccaatt tctcctactt cttctacttc ttgactttta tcaagagttg
    36241 ggccatcgag atattctgtt tcgattggaa tttcttggac aagaacttgg ggcttggttc
    36301 cttttttaac aactcttgtt tgagagtctt tttttgactt aaagtactct cagttacttg
    36361 tccactcttt ccatctacat tataagttat cgttgtaact gttttcccat tctttcctag
    36421 agtaatctct tgctcctgtc ctgcagaaag gtcattgtct gcttcatatt tagtagcaaa
    36481 tggaacaaga acttcttcaa tcttgctttt agctggaact ttgataactg tatccgtggc
    36541 ttcttttcta tcaacagtaa cctgttcggt aacataacca gtctctggat taacatcgta
    36601 ggtccttgtc gtagttacat agccatcctc tccgtcaatt gtaacaggat tttcactacg
    36661 gtcttttgtt tcatcttttt caaaacgaat tcgcgtactt gaaattttct tggttactac
    36721 cttaggttta gtcgctactt ttacaataat atccccattg tcagcgtcat catactctat
    36781 tccctcttct ttatctctag tatcatctct gacatattga atcccatcag cagcatgagc
    36841 aaaacttgta ttcagattcc tcctaaaaat aaagttagcc cgattatcgc agaaccaaaa
    36901 atctttccga gtttacgtat tgcataacgc ttattagtat tagattttgc cattacatcc
    36961 tacttctagt atagcatctt ttctatcaaa cgttaaacaa tatactttat atataaaata
    37021 gacttagaat gatatattga ttattgaact aacactttaa ctatatcgta atcaatctca
    37081 tatataaagg attgcagaca tctgatctaa atacatgcta atatatttag atacaaacat
    37141 tccaacttga taattttcac tcatctttca acattcctta cacaacgatg cagtataaat
    37201 agaatagttt tctcatcaga atgagactat tttaatatta gataatttga tagaaaaaca
    37261 taaataaaat tggttgaatt taattcccta actcgataga ggattctatt ttaaatttaa
    37321 caacagctag gattacacta taaaaagtac attaccacct gttcggctgg agaatctagt
    37381 cgattagctc cctcttagtt acaagcttaa agcgattttt taactaatac taaaccagat
    37441 taaagaagga actagaacat ctgtcttgta ctaatcaata tgctatttta aaattgcaaa
    37501 taaacttgga atgctaatta ttatatttac aataaatagt tgacttcgat agaaacagaa
    37561 aatagaattc aacattcttc cctacttata ccataataaa taagatccgc aagatagcct
    37621 tttctctcta caccattaac aatggtttgt agataggaca ttccagcctt ttccatgaca
    37681 cgacctgaag ctgggttgag actggcataa cgtgctctga ccttttgaaa acctgcttga
    37741 gtaaaacaaa agtccaagac agctttcaag gcctctgtca tcataccatg tccccagtaa
    37801 gccttgccta gcacatagcc gatttcacag cttaaatcag cctcgtctat cttaacgatg
    37861 ctgatatctc ctatcacttg ctctgggttt tcttttagac aaatggccca tttgtaatag
    37921 ttgagattag tataggaagc aacccaattg cgaatcgagt ttcgagtgat ttcgacatca
    37981 ggatggggat cccaggtaac ataggtcaga ttctcagtgg atgaagccca attttgaaac
    38041 atggcttctg catcactctc cacaaatctt cttaaaatca aacgttctgt ctgtaatatt
    38101 tgcgtaccga tagatttcat gatgctacct cacttcctta tttctatact cgtagtaaga
    38161 aggctcaact cagtaacagc tagaaaacga gtttgtcttc taatttcttg acgcagttgc
    38221 tgcctggttt gaaatgcgct ctagcaagct ttttcaaacc tagtcatcgt tgcaggggta
    38281 agacgatgaa atcgaactct tcgagttact gaatctgcct cattttctta tttctaaact
    38341 cggggttcaa gatcccccag accttctctc actttcttat ttcaagatga gaggctgaaa
    38401 acctccactg gaggtttttc ttgcttttta atttcagggc aagaagctaa aaaggtcccc
    38461 cggaccttct tcgctttctc atttctaggc tcagggtaaa aacctccagt ggaggttttt
    38521 actcccaaaa gtcatcaaat acagtgatgg gtaagtggcg tttgtgttgg cctttgtgcc
    38581 accagttttc aatggtcgct tgagcttctg ggctgattgt tttgccttct aggtagtcgt
    38641 caatctctgc gtaggtgact ccaagtgcga cttcgtcagc taggcctggt ttatcttctt
    38701 ctaggtctgc cgttgggatt ttttcataaa gggctggctc tgcgccaagt ttctgcaaga
    38761 gctgttttcc ttggcgttta ttgaggcggt aaagagggag aatatccgca ccgccgtcac
    38821 caaacttggt aaagaaacct gtgatatttt ccgcggcgtg gtctgttcca atgaccgctc
    38881 cgctatggga accagcaagg gcatactgag caatcatacg gcaacgtgcc ttgatattcc
    38941 ccttgttgaa gtctgaaaca ggactacctg tcgcttcaac tgcagctgtc atggcatcag
    39001 ctgattcctt gatattcaca accaagctga catctggctg gatgaaggct agggcttttt
    39061 gagcatctgc ttcatcagct tgcactccgt atggcaggcg gacagcgata aatttgtagc
    39121 tatcgtctcc cgtttcagct cgcagttctt ccatagctaa ttgcgccaaa cgtcctgcca
    39181 aggttgagtc ttgtccccca gaaatcccta gtacaaaggt ttttaggaag ggatgttttt
    39241 tcagatatct ttttaagaaa tcaatagaac gacggatttc ttcctgggca tcaatcactg
    39301 gtttgacacc cagctcttgg ataatcgttt cttgcaaact cattcttctt ctccttcacc
    39361 aagggcttcc ttgcgcatct tatcaatcaa gtccatctta tcttgccata catcacgcgc
    39421 caaatccact ggatagtgct gcggattgag cacacgctta tactcatccc acaacttgtc
    39481 aaattcctta cgggcataat cctgaatgtc agtcaaacta ggcaagttgt aaactaatat
    39541 tccttctttg aagatatcca ccaagagagg aacggcatca aaattacgaa ccgtcttctt
    39601 gatgtatgta taggtcggat ggaacatctt gatttctgtc atgtcgctaa tatccacacc
    39661 atcataagtg atgtagtcac cttctgactt gcctttttca cgactggtaa tgcgccacac
    39721 ctgcttctta cctggcgtcg acactttttc cgcattatta gacagcttaa tcgtattgcg
    39781 catctggccg ttttcatctt cgattgcaac aatcttgtaa accgccccaa gagccggctg
    39841 gtcataggct gtaatcagct tggtacccac accccagaca tcaatcttgg ccttttgcat
    39901 cttgaggtta aggatggtat tttcatctag atcattagaa gcataaatct tagcctctgg
    39961 aaatccagcc tcgtccagtt gctgacggac tttcttagaa atgtaggcaa tatccccaga
    40021 gtcaatccgc acacccataa agttaatctg atcacccagc tcacgcgcca cctgaatggc
    40081 agctggtaca ccgatgcgaa gggtatcata ggtatccaca agaaagacac aatttttgtg
    40141 ggtcgcagcg taagccttga aagcctcata gtcattgcca taaacctgta ccaaggcatg
    40201 ggcatgggtt cccaaaacag gaatgtcaaa gagcttaccc gcacgcacgt tgctggttcc
    40261 attggcgcca ccaatcaccg ctgcgcgtgt tccccagatg gccgcatcca tttcttgagc
    40321 ccgacgtgtc ccaaactcca tcaagggttc atcttcgata accgaacgaa tacgagctgc
    40381 cttcgtcgcc accaaggtct ggtagttgac gatgttcaaa agagccgttt cgaccaactg
    40441 acattgggct agaggtcctt ccacctgcac aatcggttca ttagcaaaaa ccaaatcccc
    40501 ttcttgggca gaacgaacgg tcaactccaa cttgaaattg cgaaggtaat ccaagaacgc
    40561 cccatgataa ccaagcgact ccaaataggc tatatcacta tctgaaaaac gcaagtcttc
    40621 aagatagttc acaattcttt ccaaacctgc aaaaaccgca tagccgttct taaaaggctg
    40681 ttggcggaaa tacacctcaa agaccgcctt cttattgtaa atcccttgat caaagtaaac
    40741 ctgcatcatg ttgatctggt acaagtccgt gtgcaatgtc aaactatcat ctggatacat
    40801 acttttccta cttccttagc tagaaaccca tgaaaatttt caagaacttt catgtattcc
    40861 aataaattag tactattata tcacatttta gctggattga gaaaagagta acaagctatt
    40921 ctccactctc caattcatcc atatcttgtt caaatttttt ctgagcccat tcgccatagc
    40981 tcttaagacc aagattgcca ataaagaccc acggaaggta aatgacataa gtaatgaccc
    41041 aagcagacag gtatttaaaa ttcaaaggat tgtgctgata aatttctatg ttgaattgat
    41101 aattctgcaa catcaaaaga gccgtaatag ccaaggttag gaaaaaacaa cccaaaatcg
    41161 taaaatgaaa acgactatag taggtcactc ccagataacg ggcacgattg aaaaagtaaa
    41221 atgtccctat gatgataacg attagcagca tattagaatt aaaaaggctt ggtgctaata
    41281 ctgaaatgat ataagatagg agcgacaaag caatgcagat atagaaactt tcagagcccg
    41341 ctttattgaa cagttgttct tctctttcgt ctagtaattg ataataataa aatctatttt
    41401 tcatcttctt cctcccaaaa tagttggtct agggttttcc ctaaacatct gcaaatagac
    41461 tggcagagcg agagactggg attgtatttt cccgcctcta tcaaaccaat agtctggcgt
    41521 gtcaccccga cagcctctgc cagttgacct tgtgttaaat cacgctctac ccgagctaat
    41581 tttaatttta aatttttagc caccttcgtc ctccttatag ttttaatact catctactct
    41641 taaaaaatcc aaaaccaaca caagctatca gctatttatt ataaccccat taatttgcac
    41701 tccagtatta tcttcagccg aaaatcagta ttttaggttg tttgaaataa acttcctagt
    41761 ttactctttt atttttattt agtattagct ttagtaggat cttttaaacg agtttttatt
    41821 gcttatattt cttgtttagt ttagttggtt tcatatcact attatataat gcttttggaa
    41881 atgagcctag tataagtcaa aaacgtgttg aatagtgaaa gcaggagcat accaagatga
    41941 ctgatttttt actgtatttt aggtatgcaa aataatacta aatgaaacta aaatgaatac
    42001 ttcttgcttt tcttgagagt gaaaaagtac aataaaatga ttgtagtgat tagcacaaga
    42061 tactgactaa tagacatcgt atttgaagcc acaaatacag gtaaagaata aaaaggaaga
    42121 agttcaattg ctttgataaa caaatcatta ctagtattca tcatcatcgt atttaatata
    42181 ttagggataa agagtagtaa agctactaaa ataccaaata ccaagccact tttcaatttg
    42241 tataaataga aaatgtagga taatagaaaa taaaacagga ctaacaaaat tgtattgact
    42301 acaatagcta ctataaaatc taatcctaaa tcacctggaa tacccaattt acttactatg
    42361 actagtaaca caatgccatt ccaagcataa ataatggaaa ctgagatggc atatagaaaa
    42421 ttagacaaga cgtaaatcat ccgattcttc tgttgattat aaaacaaact taccgtattg
    42481 tgggaaaaat ctctactaat gactcgatta gcatgtataa cagccattaa cataccgagc
    42541 atggcataaa agtttgaaat atgcttaata ccaagcgatg tcccttgagt ctttagaata
    42601 aagaatgtaa gcaatatcgg cggtataaac gagataagca aactgagata tattacgcct
    42661 gatgaatata aatttcttat actttcctta agaaaattca atttatttaa tttcatgatt
    42721 ataaccttcc tttattttga acgatttagg taaatatctt taagcgtctc ttttttagtt
    42781 tcaaaatcaa ctactttaat agagttttcg ttaaaaaatt taaaaagctc actactttga
    42841 atattcccag acatagtaat tctcagtccc tcttcctgaa caatatctcc aaattcttgt
    42901 ttggtaatga aaatgtctct atctgtagct gatgaaaaag ctatctcaaa caagaaatta
    42961 tgactatctt ttcctacttt ttgaaatgtc aaaagcccgc tctccaagaa aagaaccctc
    43021 tcacaaattt cttcaatatc ttctaattta tgactcgata ttaaaattcc cacattttca
    43081 tgtaaagcta aattttttag aaccgctaaa actatttgtg atgattcaat atctaaacca
    43141 ttagtcggtt catctaaaat caatatatca ggttccgtaa cgagagttag aagcaaagct
    43201 aatttttgtt ttgtacccaa agaataggtc tttacttttt tattaataga ctgagtcaaa
    43261 tctaactctt ggatcaaact tctaaatctt tcttgattgt agtcaacacc atataaattt
    43321 gacaaatatt ttaaattctc taaacctgtt ttagataaaa ataattttgg ttcttcgatt
    43381 aaatacccaa tattatcact gcttataata ttacctgaag tcggttgatt attctgagca
    43441 agaattttca tcaacatact cttaccaact ccatttctcc ctactagacc aacaatttca
    43501 cccttgttaa gtgcaaaatt tatgtctttg agaatgattg aatgaccata atgcttactt
    43561 acatttataa cttacatttt ttattcctcc attaatattc atggtttgct ctttgattct
    43621 tattgagttt aaaaagttgc gcctcttttt aacaacatta tatcatatat ctaacttaat
    43681 gcaatatata aatatcattt tgtaaaattt tattaacaaa aaactctcta caacaaaata
    43741 atagagagtt ttctgcttat taattttttt caaaatatct aagacatcac ttctttgttt
    43801 aatttgatag gctttgatac ctaagctccg actttatcac ttaaaaaata aaaaaggaca
    43861 gctaatctct tgcgcatcaa gggatttcgc cattctttaa tctcgtttaa gtgttgtata
    43921 tggagctttg cataattttt taaaactaaa caactacatt aagcacgaac tgtgacgctg
    43981 gttccatctt ccttataaa
//
LOCUS       DAVKEV010000018        43556 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVKEV010000018 DAVKEV010000000
VERSION     DAVKEV010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43556
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.018"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..412
                     /locus_tag="VWZ68_000938"
     CDS             <1..412
                     /locus_tag="VWZ68_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEU9371988.1"
                     /translation="PKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSGFTDAD
                     YQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDVLLLFTYLHMAAAPELADAML
                     AAKITGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            413..826
                     /locus_tag="VWZ68_000939"
     CDS             413..826
                     /locus_tag="VWZ68_000939"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEU9371989.1"
                     /translation="MGAHFLTKQAGGSGVLPGGVPGVPKGKVTIIGGGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLISNSFNIEASMRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            772..1098
                     /locus_tag="VWZ68_000940"
     CDS             772..1098
                     /locus_tag="VWZ68_000940"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371990.1"
                     /translation="MVDVAVDQGGVIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(1465..1725)
                     /locus_tag="VWZ68_000941"
                     /pseudo
     CDS             complement(1465..1725)
                     /locus_tag="VWZ68_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(1728..2228)
                     /locus_tag="VWZ68_000942"
     CDS             complement(1728..2228)
                     /locus_tag="VWZ68_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9371991.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVIDFVYAHPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            2264..2443
                     /locus_tag="VWZ68_000943"
     CDS             2264..2443
                     /locus_tag="VWZ68_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9371992.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            complement(2421..3389)
                     /locus_tag="VWZ68_000944"
     CDS             complement(2421..3389)
                     /locus_tag="VWZ68_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEU9371993.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(3475..3690)
                     /locus_tag="VWZ68_000945"
     CDS             complement(3475..3690)
                     /locus_tag="VWZ68_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEU9371994.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(3699..4553)
                     /gene="cvfB"
                     /locus_tag="VWZ68_000946"
     CDS             complement(3699..4553)
                     /gene="cvfB"
                     /locus_tag="VWZ68_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEU9371995.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGCVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(4613..5170)
                     /gene="frr"
                     /locus_tag="VWZ68_000947"
     CDS             complement(4613..5170)
                     /gene="frr"
                     /locus_tag="VWZ68_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEU9371996.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(5179..5916)
                     /locus_tag="VWZ68_000948"
     CDS             complement(5179..5916)
                     /locus_tag="VWZ68_000948"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEU9371997.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(6000..7334)
                     /gene="trmFO"
                     /locus_tag="VWZ68_000949"
     CDS             complement(6000..7334)
                     /gene="trmFO"
                     /locus_tag="VWZ68_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEU9371998.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(7629..7883)
                     /locus_tag="VWZ68_000950"
     CDS             complement(7629..7883)
                     /locus_tag="VWZ68_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU9371999.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            7878..8682
                     /locus_tag="VWZ68_000951"
     CDS             join(7878..8246,8248..8682)
                     /locus_tag="VWZ68_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEU9372000.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVKINRPKKQLANHSGKKKFHAMKAQAIVTSQGRIVSLDIAVNY
                     CRDMKLFKMSRRNIGQAGKILSDSGYQGLMKIYPQVQTPRKSSKLKPLTAEDKACNHA
                     LSKERSKIENIFAKVKTFKMFSTIYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(8671..9317)
                     /locus_tag="VWZ68_000952"
                     /pseudo
     CDS             complement(8671..9317)
                     /locus_tag="VWZ68_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(9426..9944)
                     /locus_tag="VWZ68_000953"
     CDS             complement(9426..9944)
                     /locus_tag="VWZ68_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEU9372001.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(10171..11040)
                     /gene="rsmI"
                     /locus_tag="VWZ68_000954"
     CDS             complement(10171..11040)
                     /gene="rsmI"
                     /locus_tag="VWZ68_000954"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEU9372002.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(11043..11360)
                     /gene="yabA"
                     /locus_tag="VWZ68_000955"
     CDS             complement(11043..11360)
                     /gene="yabA"
                     /locus_tag="VWZ68_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEU9372003.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(11400..12290)
                     /locus_tag="VWZ68_000956"
     CDS             complement(11400..12290)
                     /locus_tag="VWZ68_000956"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEU9372004.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(12287..12925)
                     /locus_tag="VWZ68_000957"
     CDS             complement(12287..12925)
                     /locus_tag="VWZ68_000957"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEU9372005.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLELHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMDLAK"
     gene            complement(13145..13942)
                     /gene="proC"
                     /locus_tag="VWZ68_000958"
     CDS             complement(13145..13942)
                     /gene="proC"
                     /locus_tag="VWZ68_000958"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEU9372006.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFYQLLAKAGLLVELGES
                     LIDAATGLAGCGPAFVYLFIEALADAGVQTGLPREIALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            complement(13946..15208)
                     /locus_tag="VWZ68_000959"
     CDS             complement(13946..15208)
                     /locus_tag="VWZ68_000959"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEU9372007.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAIGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(15218..16348)
                     /locus_tag="VWZ68_000960"
     CDS             complement(15218..16348)
                     /locus_tag="VWZ68_000960"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEU9372008.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(16428..18311)
                     /gene="cbpE"
                     /locus_tag="VWZ68_000961"
                     /gene_synonym="pce"
     CDS             complement(16428..18311)
                     /gene="cbpE"
                     /locus_tag="VWZ68_000961"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEU9372009.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKAN
                     DWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(18314..19201)
                     /locus_tag="VWZ68_000962"
     CDS             complement(18314..19201)
                     /locus_tag="VWZ68_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU9372010.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(19191..19652)
                     /locus_tag="VWZ68_000963"
     CDS             complement(19191..19652)
                     /locus_tag="VWZ68_000963"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEU9372011.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(19649..20557)
                     /locus_tag="VWZ68_000964"
     CDS             complement(19649..20557)
                     /locus_tag="VWZ68_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU9372012.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            20550..20747
                     /locus_tag="VWZ68_000965"
                     /pseudo
     CDS             20550..20747
                     /locus_tag="VWZ68_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(20799..21470)
                     /locus_tag="VWZ68_000966"
     CDS             complement(20799..21470)
                     /locus_tag="VWZ68_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9372013.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(21524..21745)
                     /locus_tag="VWZ68_000967"
     CDS             complement(21524..21745)
                     /locus_tag="VWZ68_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEU9372014.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            22017..22826
                     /locus_tag="VWZ68_000968"
     CDS             22017..22826
                     /locus_tag="VWZ68_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9372015.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(23007..23882)
                     /gene="aguB"
                     /locus_tag="VWZ68_000969"
     CDS             complement(23007..23882)
                     /gene="aguB"
                     /locus_tag="VWZ68_000969"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEU9372016.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYNLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(23892..24977)
                     /gene="aguA"
                     /locus_tag="VWZ68_000970"
     CDS             complement(23892..24977)
                     /gene="aguA"
                     /locus_tag="VWZ68_000970"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEU9372017.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(24974..26101)
                     /gene="nspC"
                     /locus_tag="VWZ68_000971"
     CDS             complement(24974..26101)
                     /gene="nspC"
                     /locus_tag="VWZ68_000971"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEU9372018.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(26101..27360)
                     /locus_tag="VWZ68_000972"
     CDS             complement(26101..27360)
                     /locus_tag="VWZ68_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEU9372019.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(27357..28217)
                     /gene="speE"
                     /locus_tag="VWZ68_000973"
     CDS             complement(27357..28217)
                     /gene="speE"
                     /locus_tag="VWZ68_000973"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEU9372020.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            28472..29187
                     /locus_tag="VWZ68_000974"
                     /pseudo
     CDS             28472..29187
                     /locus_tag="VWZ68_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(29153..30628)
                     /locus_tag="VWZ68_000975"
     CDS             complement(29153..30628)
                     /locus_tag="VWZ68_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU9372021.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            31335..32330
                     /locus_tag="VWZ68_000976"
     CDS             31335..32330
                     /locus_tag="VWZ68_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU9372022.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVRKSSVTKELKEKILHYHNQ
                     KFSPEMMVMVKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKSAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSADVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGIKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSVRNKSRN"
     gene            32356..33000
                     /locus_tag="VWZ68_000977"
     CDS             32356..33000
                     /locus_tag="VWZ68_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEU9372023.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATSNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYASYIQNGEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(33042..35030)
                     /locus_tag="VWZ68_000978"
     CDS             complement(33042..35030)
                     /locus_tag="VWZ68_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9372024.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(35032..35790)
                     /locus_tag="VWZ68_000979"
     CDS             complement(35032..35790)
                     /locus_tag="VWZ68_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9372025.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            36218..36409
                     /locus_tag="VWZ68_000980"
     CDS             36218..36409
                     /locus_tag="VWZ68_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372026.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(36763..37035)
                     /locus_tag="VWZ68_000981"
     CDS             complement(36763..37035)
                     /locus_tag="VWZ68_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU9372027.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(37093..37542)
                     /locus_tag="VWZ68_000982"
     CDS             complement(37093..37542)
                     /locus_tag="VWZ68_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEU9372028.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTQRYRCGLCRGKLLLVNQPED"
     gene            complement(37529..39658)
                     /locus_tag="VWZ68_000983"
     CDS             complement(37529..39658)
                     /locus_tag="VWZ68_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEU9372029.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            complement(39760..40764)
                     /locus_tag="VWZ68_000984"
     CDS             complement(39760..40764)
                     /locus_tag="VWZ68_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1919 domain-containing protein"
                     /protein_id="HEU9372030.1"
                     /translation="MTENLTNVQVLQKMDDTDHRIRKQYRSLFGKLFNSKLLRKINQF
                     DINNLIWRLYIHSKTATYINFPTYIYKPVIDAKPLKDSYKIILENYENRIKDCAVLEN
                     YDIERAKKQYIQELANFSAWLKNDGEYLDSDIVYHKLIAAEKGIFPFLELDRLDFTII
                     SNNCVGGLIYKQLGFQYRTPFVGLFILPDDYYKLTKHFRYYMEQELVFEEELISPSWT
                     HEVYPLGHLGDIDIHFLHYSSIEEARTKWEKRKKRINWNNLYFKFDNKDSASEEILNK
                     MDNLPYSNKLILVNRPYKNLKSQCVIPGQEHLPELAIMSDPLNTFDIMAWLKKGGNAL
                     "
     gene            complement(40769..41128)
                     /locus_tag="VWZ68_000985"
     CDS             complement(40769..41128)
                     /locus_tag="VWZ68_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9372031.1"
                     /translation="MLHQGDKNSLLESLSIVERQTLKDIEVIIVNQSTEEIASISQQM
                     NLSFNIKIIDENSFAELSDMITGDYITFLSSNDSLFDWTFEKMYHAIKLSDSDVVLGH
                     FADLVDGVFYFYPFGGG"
     gene            41470..42375
                     /locus_tag="VWZ68_000986"
     CDS             41470..42375
                     /locus_tag="VWZ68_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEU9372032.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            42372..43187
                     /locus_tag="VWZ68_000987"
     CDS             42372..43187
                     /locus_tag="VWZ68_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEU9372033.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(43317..>43556)
                     /locus_tag="VWZ68_000988"
     CDS             complement(43317..>43556)
                     /locus_tag="VWZ68_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9372034.1"
                     /translation="KQVHPLFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLI
                     KRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT        12787 a         9649 c         8002 g        13118 t
ORIGIN      
        1 cccaaaagaa attaaaaata acgaaaaccg tgtcgccctc acacctgcag gtgttcatag
       61 cttagttagt cgtggtcatc gtgtccttat cgaaacaaat gctggtctcg gttctggctt
      121 tactgatgct gactatcaaa agcaaggagc tgagattgtc gctactgctg gtgaagcttg
      181 ggcagcagag ttggttgtga aagtaaaaga acctttaagt tctgaatacg gttacttgcg
      241 cgacgttctt cttctcttca cctacttgca catggccgct gctccagaat tagcagatgc
      301 tatgttagca gcaaaaataa caggaattgc ctatgaaact gttcgtgaca atcaaggaca
      361 actaccgctc ctcgttccta tgagtgaggt tgcaggtcgt atggctgttt aaatcggagc
      421 tcacttcctt actaagcaag ctggtggctc tggtgttcta cctggtggtg taccaggtgt
      481 tccaaaagga aaagtaacta tcatcggtgg tggtgtcgtc ggtacacatg ctgcccgcat
      541 cgcccttggt cttggtgctc aagtgactat tttagatatt agtgccaagc gtctctcagt
      601 tctagaagaa gtctttggaa gtcaaattca aactcttata tctaattcat tcaacattga
      661 agcaagtatg agagatgctg atgtggtgat tggagccatt ctcatccctg gtgcaaaagc
      721 accggaattg gtgacagatg agatggtcaa acaaatgcgt ccaggctctg tatcgttgac
      781 gttgctgttg accaaggtgg cgttatcgaa acagctgacc gtgtgacaac gcacgatgaa
      841 cccgtctatg aaaaacacgg tgttctccac tatgccgttg ccaatatccc tggtgcggtt
      901 gctcgcactt caaccatcgc cctaaccaat gtcactcttc cttatatcga agctttggct
      961 ggcaaaggat tcgcacaagc aatctctgaa gatgaaggct tgcgtcaagg tgtgaccact
     1021 tatcaaggtt acttgactag cctaccagtt gctcaaggac ttaatcgtga ctacactgat
     1081 atcaatgatt tagtataaat tttgaaaaga aaagggtgac ttcgcaagtc ctacccactg
     1141 tgctttgtgt catcagctat tacatcgttg gtttattgta ctgtatactt tgcaactgga
     1201 gactttcgtt ccagactcaa ttgtgcataa gaaactctaa attgaataaa gtcaacagag
     1261 tttcgcccaa ccacttcgtc ttgtaatgac aattatataa accaaaggaa gctgagctct
     1321 ttagtcccag cttcttttta tatataaaat tttacccgtg caaagacagg gccttagcag
     1381 acttcttttt tacttcgttc acccttgctt tttcttttta ggtttgggcg ttggcagttg
     1441 gttatacata gctaaaatca ggtcttatag aaacatctta ttatcaagtt cttccactca
     1501 aatcatttct ttggcacctt tgtatggaaa ctcaaaaaaa gattggtcaa tcttatctaa
     1561 gactgcttgc acgggtttaa ctaaaaagcg atcatcataa atgccgccaa taatcttgcc
     1621 gcggaagtaa agaatatact cccccatcat ggaacggtaa gtcacatcat ctaatcctga
     1681 taattgttcc aaaacaaatt ccaaatagtt cttacttgat gccatttcta atcttctagg
     1741 ctctgttcag cgataacaac cgtatagagt tcttgcttaa cctcgcatcc aattgattta
     1801 aagccctgct tttcccaaaa atgctgagat tgcggatttc ccttaacata agccaaacgt
     1861 gcctttcgaa agttcttagc aaaataagct agtgcttctg tcacaatatg actaccaatc
     1921 cctttcctct gataggcttg atcaaccata aacaaaccaa taaaaacagt ctcctcatca
     1981 ggatgtgcat agacaaaatc tataacagcc acaaggtcag atccattcca aaatccaaca
     2041 aaaaacttat cagccttagc tttaccttca ggtagacaaa gcatgtcctc ttttacagtt
     2101 gcaaaatttg gctctggtgg acaatgctga aaatacagag gattactttc atataaagat
     2161 aaaatacttg gaatatcctt ttcagttagt atcctacaac tgtaatactt agatagttgg
     2221 tcaatcatct tttcaaattc ctactttctt gtgccctgtg attatgacac aggaagatgc
     2281 actgatcgtc atcagccaca taaaagttct ttccatcgtg cctaatcgtt gtctcaaacc
     2341 tttggataaa acctttagcc tatacaactg gattttcctc tctcaaaagt atattctttt
     2401 gcaggcaaac ttcctcaaaa tcagtcgtgt gcaacttcag tagaatattc ataggctcgg
     2461 ataatctgag cgacaactgg atggcgaacc acatccttgg ctgaaaaatg aacaaagtca
     2521 atctgatgga tgttcttgag tttctcttga gcatcaatca aaccggactt gacattacgt
     2581 ggcaggtcaa tctgactaat atctccattg acaatcatct tagaatgaaa acctaaacga
     2641 gtcaagaaca tcttcatctg catgatggtc gtattttgcg cctcatcgag aatgacaaag
     2701 gcatcatcca aggtccgtcc acgcatatag gcaaggggcg caatctcgat aatttcacgc
     2761 tccatgagtc gagttgtttg gtctttcccc agaatctgat acaaggcatc gtaaacagga
     2821 cgaaggtaag gatccacctt ctccttaaga tcacccggaa gaaatccaag actctctccc
     2881 gcttccaccg ctggacgagt taggataatt cgcttgactt gcccacgttt aagggcagtc
     2941 actgccaagg tcactgcaag gaaggtcttc cctgtacctg ctggcccaat tccaaaggtc
     3001 acatcatgct gtttgacact gtccacataa agcttttgcc ctagggtttt gacacggata
     3061 ggtttcccag tattatcttt gataatttct tcttcgtaaa gggcgacaaa cttgtcaatt
     3121 tcatcatttt tgaccatgct aatcgcagtg actacatctg gcgtaccaac ggtcatccca
     3181 cgatttacca agaccatcaa agcctgaata acttgacggg cttcctcaca ggcagactct
     3241 tctcccaaaa cctggacaat ctccgtacga gcatgaatca caacatcaag ctcttcttcc
     3301 atcaaacgaa gatggcgttc attggaacca aaaagatgaa acaggtcatc tggatgactc
     3361 agttgaatgt ctattgaatg ttccttcaaa taaagaacct ctctaatcct tttatttctt
     3421 tttattatag cagagggatg gagaaattac tagcccaaac ccaatgaata aatgctagtg
     3481 ttctagatat tcctgccaaa tgctgtcaaa atctcctagg ttaaaagaga aactggcatg
     3541 ctcctccaaa aagcgactga cctcatcaaa atcatctgta tgttttggaa aagctgcctc
     3601 ttcaaaagcg aggtctgcca aaattgcttt gggactgtta cttttaggat tgcgctcggt
     3661 catgagccaa gtgtaaaatg attttctcat aagcctccct aaatcaactc tgtcccaaac
     3721 tggtcctgct tgattttacc agccttcata agaccaccta aagctttctt gaactgacct
     3781 ttagaaatgc caaaggttgc cttgatgtcg tctggagatg acttatcatt taaggtcatg
     3841 aaaccgccat tactttccaa ataagtcaaa atcatctgag catcgttttc caacatttca
     3901 aaggagcgtg gtttgaggga gaggttcaga gtgcggtcca cttcacggaa accaataacg
     3961 cgcgcatcta atacttgccc caaacgtggc tctgcgtaac gctcgctagg atgaataaaa
     4021 ccaagcatat tattttctgg taggtaaaca aaagttcctg acagcttgag acggtaaaca
     4081 atggctggcc agttttggtt ctgcatgttg ttgtaggcag gacgagcaag acgttggaag
     4141 tcttcttgat aagccaagag gccccagata cggtctttct tatccacttc aagacggatg
     4201 tagagttggt cgcccttctt aggccagagt tccttgagct cagggagaat atcgagtgac
     4261 acaacgattt ccttgtcagg aaggcctgta tctacaaaga cacccaagtc cttacgaacc
     4321 tctgtgacac atccccaacc aaattggtcc tgagtggcag tcacttctaa ggttgtcagg
     4381 cggagttttt gcttcatatc cgtgtatgca aaacctttga ccgtatcccc tactgtatgt
     4441 tggccctctt ccttagcaag agcataggtt tgaccatcct tttgcacaaa gtaaaaacgg
     4501 tcattttcat cgatgatcag tccaacgata aaacttgcaa gatttgtatt catatttcct
     4561 tctttcgaat aaaactcagc cagcaatgcc aactgagttt ttctgtttat ttttagactt
     4621 ccaaaagttc tttctctttg ttagcagtca tgtcgtcgat gtgtttaaca gcatcgtctg
     4681 ttactttttg aatatctttt tcaagagtct tcaattcgtc ttcagtgatt tcttttgctt
     4741 tttcttgttt cttagcttcg tccatagcat cgcgacggat attgcggaca gccactttag
     4801 cattttcgcc gaccttcttc acttctttag caaggtcacg acgagtttct tctgtaagag
     4861 ctgggataac caagcgaatc acagaaccgt cattagccgg tgtgatacca agatcagaag
     4921 cgttcaaggc acgttcgatg tctttcaatg aagacttgtc aaatggtgtt accaacaaaa
     4981 cacgcgcttc tggaatcgta attgaagcga tttggttaag aggagtttcg actccatagt
     5041 attctacatg tacacggtca agcaagcttg cattggcacg accagcacgg ataccaccaa
     5101 attcacgagc aagtgattgg tgagattggg tcattctctc tttagctttt tcaataatta
     5161 cgttagccat attctttctt attccttttc ttcgatatta tttgaaactg ttgttccgat
     5221 attttcacca aatacgacac gtttgatgtt gcctgattgg ttcatgttga agacaaccaa
     5281 gtcaatgtcg ttgtccattg agagggttga ggctgttgag tccatgatac gaagaccttt
     5341 gttgataaca tcacggtggg tcaattcttc aaacttaacg gctgtcttgt ccttcttagg
     5401 atcggcattg tacacaccat cgacgccatt tttagccatg aggatggcat ctgcttcgat
     5461 ttcagctgca cgaagggccg ctgttgtatc tgtcgagaag tatggtgaac caattccagc
     5521 accaaagata acgatacggc ctttttcaag gtgacgaagg gcacgtccac ggacataagg
     5581 ctctgccact tgttgcatag caatagctgt ttgtacacgc gtatcaaccc caacttgttg
     5641 caatgaatct gccatcacaa gagcattcat aacagtccca agcattccag tgtaatctgc
     5701 ctgaacacgg tccatacctg cttctgctgc aggttctcca cgccaaagat ttcctccacc
     5761 aataacaagg gcaatttcga tacctaagct atgaacttct tgaatctctt ttgcgattgt
     5821 ttgaactgtt tggatatcaa tccctacgcc acgttcaccg gcaagggctt cacctgataa
     5881 cttgattaaa atacgtttat acttgggatt cgccattttc actctccttc tttcatccta
     5941 cctattttat cacaatttct aagattttta tagtatcatg agcaattctt tcaaaaaaat
     6001 tagacagtca aaaattcctc taagtcggca agggcacgct ctgcaatttt ttcataacga
     6061 gccttcttat cacggatacg ctcgccttcc aactccttga tgatcccaaa attgacattc
     6121 attggttgga aatgtttgct gtcggcatgg gtaatgtaat gagctaagct tccaatcgct
     6181 gtcgtctcgg ggaaaataac ctcgctttct tccttgaaga gacgagctgc gttaattccc
     6241 gcaactaagc ccgaagccgc cgactcaaca tagccttcca cccccgtcat ctgaccagca
     6301 aagaagagat ttggttgttt cttggaacgg taagtctgct caagaagatt tggtgaatcc
     6361 atgtaagaat tgcgatgcat gacaccataa cggacaaact ccgcattttc aagacccgga
     6421 atcatttgga agacacgctt ttgttctccc catttgaggt gggtctggaa accaacaata
     6481 ttgtagaggc taccagctgc attatcctga cgaagttgca caaccgcata aggtgtttta
     6541 aattctccat cacgaggtcc tgtgtagtcg tccggatact caagaccgac tggcttcata
     6601 gggccataaa gcatagtttt aatgccacgt ttggccataa cttcgattgg catacatcct
     6661 tcaaagtact tttctttttc aaaagaattg agcggtgctt cttccgcatt gaccaaggct
     6721 tcatggaaat ccataaactc ttgcttggtc attggagcat tgagataggc tgcttctccc
     6781 ttatcataac gagatttgag atagacctta ctcatatcga tagtgttgac atcgataata
     6841 ggcgctgctg catcgtagaa atagaagcca tcgccattat taagggcatg aatcttttca
     6901 gccagggcat cgctagtcaa gggaccagtc gccacaactg taataacatc tgttggcaat
     6961 tctgtaattt catcacgcac cacttcaatc aaggggtggt tgaccacttt ttcggtcacc
     7021 atttgagaga aaccatcacg atccaccgca agggctccac cggcaggaac acgtgtagcc
     7081 tcagcagatt ccaagataac agaacccaag cgacgcattt cttccttgag aagaccaact
     7141 gcatttgtca aagcatcccc acgcaaagaa ttggaacaaa ccaactcagc aaaattgtct
     7201 gttttgtgct gaggagtcga cttgacacca cgcatttcat aaagtttaac tggaatacca
     7261 cgctctgcga tttggtaggc tgcttcagaa cctgccaaac cagcaccgat aacattgata
     7321 taagattgag acacgacact aatacctctt tgggagtgtg aagttaagat tcacattgaa
     7381 aaagccaatc agacttacga gatttcgagt ttcttggctc aggctgaaaa agtcccccag
     7441 actttcctcg ctctcgaatt tcttggctca agctgaaaaa gtcccccgga ctttttcact
     7501 cccacaaatc tttctatttt tttcttctac tagtataaca aaaaaaggga agaaggcaaa
     7561 cttccctgtt tagtcatttt cttgatgtaa agagatagag agtattccag ttaagaatca
     7621 attatatgct actctataaa atcttttcca cataacggat cgatagggac tgttattcta
     7681 tctcttgcta taaccgtatt atctaaaaca gcataacatt caacatagtg atctccttta
     7741 aactgtgaat cttcgtgata ttttatttta cctgaaaaaa tagcaccacg ctcacaattt
     7801 cttctaatag cctcagcttc aatatttctt actttccaat agacttcctg cgaaacaaaa
     7861 tatggtatag tagttctatg aatgatgaag caagtaaaca actaactgat gcacgattta
     7921 agcgtcttgt tggtgttcag cgcacgactt ttgaagagat attagctgta ttaaaaacag
     7981 cttatcaact taaacacgca aaaggtggac gaaaacctaa attaagccta gaagaccttc
     8041 ttatggccac tcttcaatat gtgcgagaat atcgaactta tgaacaaatt gcggctgatt
     8101 ttggtattca cgaaagcaac ttaatccgtc ggagccaatg ggttgaagta actcttgttc
     8161 aaagtggtgt tacgatttca agaactcctc tcagttctga ggacacggta atgattgatg
     8221 cgacggaagt aaaaatcaat cgccctaaaa aaacaattag cgaatcattc tggtaaaaag
     8281 aaatttcacg ctatgaaggc tcaagcgatt gtcacaagtc aagggagaat tgtttctttg
     8341 gatatcgctg tgaactattg tcgtgatatg aagttgttca aaatgagtcg cagaaatatc
     8401 ggacaagctg gtaaaatctt gtctgacagt ggttatcaag ggctcatgaa gatatatcct
     8461 caagtacaaa ctccacgtaa atccagcaaa ctcaagccgc taacagctga agataaagcc
     8521 tgtaaccatg cgctatccaa ggagagaagc aagattgaga acatctttgc caaagtaaaa
     8581 acgtttaaaa tgttttcaac aatctatcga aatcatcgta aacgcttcgg attacgaatg
     8641 aatttgattg ctggcattat caatcatgaa ctaggattct agttttgcag gaagtctaat
     8701 gtaattctca agctgtgagt tcattatgat ttgtaaatcc gatatatctt cagcagctaa
     8761 aaacacattt tgaaatgttc caagtccgtt ttcaccaaaa ctatattctc tcttactata
     8821 cttactctta ttattctcta tatagttaga gtcaaggttc ttaacctctt gaagttcatt
     8881 ttctttactt ctgaggttaa aatcttttac ttctgaagtt aagttttttg acttctgtaa
     8941 gtcattttct tttacctgaa atatactcat aaagtcttta acataaatga tgttcggctt
     9001 accaagtcca agccttactc tttcgatcag tcctattcct tttttacatc aagctcatct
     9061 aatgttttta tggcagttgg ctttgagata tttcttcttt tcataatttc ttcgacagta
     9121 aaatagataa atactctgcc ttccttgtct atccagttat tcttaaatga cattcctgtc
     9181 tgtttaagaa gtatggaata aaggataatt gcttctgctg ataagccccg aaattcttct
     9241 ctatcaacta atatctccgg tacttttaag aagttaaatc tttccgcttc tctgttataa
     9301 aaatattcaa agtccatgca agatcacctc ccttcttaaa aatttgcaaa gaaaaagacg
     9361 atagtttttc ttctatcgcc tttggtaacc atttttatga aattttttaa agttaaaaat
     9421 ataatttata atactatctt cttccatttt ctgattttag ttctgaaagt tccaaaaggt
     9481 gcaaccgtat ttacatgaat aaacttatac acttcccaag tcgctgtttt agtcgcttca
     9541 tcagcccact ttctcatatg cggttcaaat aattcttcct cactcaacga atcaatcatt
     9601 gcagagatag aattaatatt ttcatttaat tttgctttca actcttgcag agataaatga
     9661 gcgtaggtat ctgtgaacca ctgatataat tcaccaagtt gattccattt aaatttatcc
     9721 gatggtgttt ttacttgaag cccctttctt tcatcttctt cccatttaag aaccaagttg
     9781 gtccaaccaa cctgataagc aaggttttct gctggagttc tgtcaacttc atcagctctc
     9841 ttatctttta aattttctgg aatattatca aattctaaaa tatatttctc aaatgttttc
     9901 tctatctcag cttttagttc ttctttattt tcgtatgttc gcaaaaaatc accttctttc
     9961 tgatttatca atcctttgat ttaaaatgac cttatttttc tatttatacc ttctaagaac
    10021 gctataactg ctgctccaac catcggtatt ccgtatgggc ttaataaaaa acttaatacc
    10081 aaagcttcta taccaagtga tacatcttta tattatcatc actaattaag ttaaacagaa
    10141 acagacagaa ttattacatc ctgtctccct ttattgtttt tcttcccagt cgtggtaggc
    10201 agcgtagagc tgacttttat tccactggta aatcttagcg acttccttga tagcttggtt
    10261 tttcttcaca ccttgctgga tgcgggtttg aatttctacg aacaagtctt cctcgtcctt
    10321 ttcctccaca ccctgactgg caccctcaac aatgagaaga cattcgccct tgagtggcgt
    10381 ttcagcaatg ctttctaata actcagagat agtacctcgt tggtattctt catagatttt
    10441 ggtcaattcc ctgaccaaga caacggagcg gtcaccgtag acttctaaca tattttccaa
    10501 cgtgtctgct acacgatgag gtgattcata aaaaatctgt gtttcaggat aatctttttt
    10561 caagccaaaa aattgcttct gctgacctga ttttctcggt aaaaaaccgt aaaagatatg
    10621 tggctgtggc gctaaaccac tggcaatcaa ggcagaaatt cctgcagagg cacctggaac
    10681 tgtcacaact gcaatttctt cctcaatagc tgccttaact aaatcatgac cagggtctga
    10741 aatgctaggc aaaccggcat cagagacctg agcaatactt tgccctgctt tcaagaaacc
    10801 aatcaaatca ggaatttttt ccttggcatt gtgctcatga aaactgatct gcttggtgga
    10861 aatgtcaaaa tgcttgagca aaagccctgt attgcgcgta tcctcagcag caatccagtc
    10921 cacttctttc aaggtctgga tagcacgaaa agtcatatca tctagattgc caatcggcgt
    10981 tgccactaga tacagcttgc catagggaga ctgcccctta aaactttttt gaatttgcat
    11041 gcttactccc tgtataacaa ctcatcacag aacatacatt cttcgtcctg ctctcgacgt
    11101 tgtccataaa aatcattaca tacgtgaaat ccatcacggt aaatacgacg gacactttcg
    11161 cgaacatgct tggccttgac gggagcgtct gcttccacct cacccaagcg ttctcgcaac
    11221 ttactatttt ccaagcgaag agctgtattt tcttctacca agctcttgag atttttcttg
    11281 atggcttcca catcggctaa ggttaccaat aattgttggg aaaaatcatc cagcgcgtca
    11341 aataattctt ttttgtccat aaaacagccc tttcctttct ttatcattca tttttgagtt
    11401 tatatttctt tcaagaccag atattccatg gcattttgaa agctgacatt agcttgccac
    11461 atttttctag cttctagtaa atcttgtaga atcactctta ctcttacctg caagaggtcc
    11521 tgcccacaga gaacttcaag aatccgtaaa acctgatcct gtttttcctt atcatctgcc
    11581 aagttggcta atttggcaac ctgtagataa ctttcttttt tcttagctac taaccaagtc
    11641 agcaggcgtt cactttcatc gaccaaggtc caaaaacttg cctgattagc caacttttct
    11701 gcttcagctc gcgattgact aaacttagct aaaagagtcg cttttttctt aacaagtccc
    11761 atttgttcta agagtaagat aagtttttct tcttgctttt taaagtggaa gatctgagtc
    11821 cgacttcgga ttgtcggtaa catcttttcc tcatcgctag tcaagaagaa aatataaact
    11881 tcactctggg gttcttcgat gaccttgagc agagaattgg ctgcgttggg atgcatttta
    11941 tccgcttgct cgataataaa gacctgttgc tggctttcaa tccctgcttg agaaaactgt
    12001 cccaccaatt cccgaatgcg ttctgtcttg atgacctgat tgactggctt aatcaaggtg
    12061 acatctggaa actcttcctg ttcaatcagc ttgcaacttc ggcatttctc acatggtaag
    12121 acgccaactt tatccgtaca aaagaggctc ttagctaaaa attgcgccat ttccaagctt
    12181 ccaaagaaac ctgaaaagag ataggcgtga ttgagctggt cttgttctaa gatacggaca
    12241 aaacggtcaa actgagctgg ttgccaagcc tttagttgat cttgtttcat ttggccaagt
    12301 ccattccgtc aaacaagaca gccttggtag tttccacaac ttgctccaaa gggagactag
    12361 catcaatctt gacaatgcga tttccttctt tttccaggag agaaaggtag ccttgacgga
    12421 ctttcttgtg caattccaaa ccttccaagt ccagacgatt gacctcgcgg tcactattcg
    12481 cagcaatgcg agccagccct tcttccacct cgatgtcaaa atagagtgtc aaatcgggtt
    12541 tgaggccatc tgtcgcaaac tgattgagcc agtcaatggc ttcaatatct aagccacgac
    12601 caaatccctg ataggcaaca gaactatcga taaaacgatc catgatgacc aacttgccag
    12661 cttcaagggc tggaagaact ttttccacca aatgctgtct gcgactggca atatagagaa
    12721 gtagctctgt tttagcatcc atctgagtat gacttggatc caaaatcact tcccgaatct
    12781 tctccccaat caagactccg ccaggttcac gggtcgtcag cacctttact cctttttcct
    12841 ctaaaattgg tagcagagcc tctaaaacac tggtcttgcc tgctccctct ggtccctcaa
    12901 gagagactaa aaatcctttt gacatgtcta actcatttct tttttactac ttctattcta
    12961 tcaaaaaaat aggggtttgt gacaatcttt ttgtcttctc atttcatact caatgaaaat
    13021 caaagagcaa actaggaagc tagccgcagg ctgtacttga gtacggcaag gtgaagctga
    13081 cgcagtttga atttgatttt cgaagagtat caaccaccat aaaagaggca gataaaacta
    13141 cctcttattt acctagttct tgtgttcgtt tgtaggcttg atgaactgca tccatgactg
    13201 ttcctcggaa agcatgcgct tctaggcttg ctacaccagc gatagtcgaa ccgcctgggc
    13261 tacagacttg gtctttcaat actccaggat gttgctgact ttcaaggacc aattgcccag
    13321 ctcctaccac agtttgtgct gccattttca atgctatttc tcgtggtaat cctgtctgaa
    13381 cacctgcatc tgccaaggcc tcgataaaaa gatagacaaa ggctggtcca caacctgcaa
    13441 gacctgtcgc tgcatcgatt aaactttctc ctagttcaac caagagacca gccttggcta
    13501 aaagctgata aaagagctca ctgtcctcag ccctgcaatt aggagacaag gcataactaa
    13561 tcactccttg cccgatagaa gcaggggtat taggcatcat acgaataatt cggtgttgac
    13621 ttgggataag acttgctagt ttttctaagg tcaatccagc tgccatcgaa atcaaaagaa
    13681 gactttctct tttttcaagg atggtctggt attgagaaag cagttcagaa aactgagcag
    13741 gcttaactcc tagaaaaatc acatctgctt ctgcaaacat ttcttcattg ctggaagcct
    13801 gaccaccaaa gtctgcaatg aaagcatcta ccttagcttg actacgattg gcaaggagaa
    13861 tctcatctga cgtcctagtc tgcaagacag attttgccaa gctagcaccc atattcccca
    13921 aaccgataaa tccaatcttc atctcttact cccttatctg cccatcaccg gcaaccacat
    13981 acttgtagct ggtcaactct ttcaagccca tgggaccacg cgcgtgcaat ttctgagtag
    14041 aaatccccat ttcacaacca agaccaaatt gtcctccatc tgtgaaacga gttgaggcat
    14101 taacatacac cgctgcagag tccacttgat ctgtaaagta tgctgcagct tcagcatttt
    14161 ccgtcacaat agcatccgaa tgatgggtgc tgtgggattc aatgtgcgca accgcttctt
    14221 ctaaactgct cacaacctta acagcaagga catagtctaa aaactcggtg tcaaagtctt
    14281 gggtctcagc tgcttgacct gaaacaaact ggcttgcttt gctatccaag cggaattgaa
    14341 ttggttccag tccagcttcc ttacgctctg caaccagcat ttgatccaag cgaggaagga
    14401 tgcttgctgc cttgttttca tgaaccagca gaacctccat ggcattacaa acagaaggac
    14461 gactggtttt agcattgttg atgatagaca gcgccttgtc ttcgtctgca tccttatcca
    14521 catagacatg gacaatccca gtccctgtct cgataacagg tacaatcgca ttctcaacca
    14581 ctgcattgat caagccagct cctccacgag gaatgagaag gtctagatag cccttggcct
    14641 tcatcatagc ataactactt tcacggctag tatcctccac cagttgaatc acatttggat
    14701 gaatagtagt cgtctccaag cccttcttca aggctgtgac aatggcatgg gttgtttgat
    14761 aggcatcctt accactacga agaacaaccg catttccact cttaagagtc aaagcagccg
    14821 catcagacgt cacatttgga cggctttcat agataatacc gatgacacct atagctacac
    14881 gtttttttgt gataaccaaa ccattttcaa gctgacttgt ttctaaaact tcaccgattg
    14941 gatctggtaa ggcaaccact tcacgaattc ctcttgccat cgcttctata cgatctgcat
    15001 ccaaataaag acgatccaac atcacatctg agattttccc cttagccgct gccatatcga
    15061 gggcattagc cgctaaaatt tcctcagtag cagccactaa gtgatcagcc atggctagca
    15121 aggcttggtt tttcacttct tcactagctg tgttaatcga ttttttaaca gcctgtacct
    15181 gttcaaattg ttcttgtcta ctcaccatag tttacctcta aaattctgta aaaagtagtt
    15241 ggatttcagg agtaatggaa atccagtcgt cacggtaaat caagacaccc ttggcttttt
    15301 gagaacgcaa catatcctcc aaagcagatg ctccaaattg cacgcgtcct tttccaagtg
    15361 attttccact ttccttgtca aatactgtca cgatatcacc gtaagaaaag gctccttctg
    15421 cttcaacgat accagataag agaagactct ttccatgttg agagagagct tccgcagccc
    15481 ctttatcaac ccaaatagaa ccttgactct gagcatagaa ggcaagccat tgtttctggg
    15541 tacgaagccc cttctcttga gcaacaaagt aagaaccatc ctcggtctcc tctgccgcct
    15601 caatcatgga atctgatttc aaggatgagc agatataaac aggaactcct gattccgtcg
    15661 cgatagttgc agccttgatt ttggttaaca tacccccagt tccgtttgac gaaccagctc
    15721 caccagccat atcaataatc tcacgattga tggtctcgat tctctccaag cgtttggctc
    15781 ttggatctga attaggattt ccagtataga gaccgtccac atctgtcaag aaaactaaaa
    15841 ggtctgcttg gaccatcgcc gctacttgag cacttagagt gtcattgtcc ccaaccttga
    15901 gctcatcaat aacgacacta tcattctcat tgatgatagg aattgcccca cggttgagca
    15961 aaaccgacaa agcctgatgg gcatttttat aacgacgctt atccacaaag tcatcttggg
    16021 tcagcaagat ttgtgcagaa acgatttgac gcaagagaag attggtcgta tattcttcca
    16081 acaaaagtcc ctgccctacc gctgctgaag cctgtttatc agcaatttta gtcggacgct
    16141 ttttaaatcc taaggctcca aaaccagccg caatggcacc tgaagacacc aaaatcaact
    16201 catgaccagc ctcgtgcagc atagccaact gctgggtaat atcctttacc ttactacgtg
    16261 ataaacttcc atcctcattt gtcagagaag aagtacccac cttaaagaca atccgtttgt
    16321 atttcatagt ctcactccga ttattcatat ttatccatta taacatgaat aacaggaaat
    16381 agaaaagagt tgataggaaa aagaaggccc taaaaccttc ttttctacta ctgttctgat
    16441 tccgatttgt ttacactcgt ttcagagctt tgtgaagttg aggatgtcaa atcttgacta
    16501 gttgaaaaat ttgtaacact ttcatgttga ctcgtttctt tattttcaag atcctttttc
    16561 actacttctt tggattcttt tatttctgaa tgacttgtag ttttaattgt agcagatttc
    16621 tcgatcgaaa catccactaa ccaggcacca cttgaatcca cagtataacc ttctggtgtc
    16681 ttaccgttca caagtaattg accattttct ttcaagaagt accatttatc cttgtccttg
    16741 atccaaccca cagctcgtga accgtctgtc ttgtagaaat accaatcatt tgccttttta
    16801 tgccagcctt gcttcatagc tcctgaatct tccagataat aatgttgacc agcaacttct
    16861 atctcacctg tcttcatgac accagtagaa tccatatagt accaggtttc tttatctttt
    16921 acccagccca ttttcatttc ccctgatgga gcaaagtaat accattgccc catatattga
    16981 agccatcctg tcttcataga accatcaaca tccaaataat accactgctc tttatcttga
    17041 atccaaccaa tttccatctg gttttctttg ttaaaataat accagattcc agcgattttc
    17101 ttccaatttt tagcagaagc accagagtct gtcaaataga accaatgatt gttccatttt
    17161 ttccattgat tctgtaacaa gatacccgtt tggttaaagt aataccattc accttcgatt
    17221 tcattccaac cgacagcata ctctcctgta gaatcaggcg cttgatacca ccagttccca
    17281 tatgcactct tatgccaacc agcttgaaaa cttggaatcg gcttgtagga tgttgaaata
    17341 ttgacaaaac cgtcttttcg aatatcaaaa actgttgcat catagtcttt gctggctgcg
    17401 ttgattctct caattcctcg ttctttgagc caattaacat actcactatc aacaccattt
    17461 ttccaaggta gactatccga agtttgaaca atcaaactcg gactcaaatt tttaatgaaa
    17521 tccttggtat ttgatttgtt ggtatcatgg tgatgattaa acttcatcaa atcaactttt
    17581 ccaatgagag gaccatactt gtcttctgct ccatgaacat tatctaaatc gcccccaagg
    17641 taaattttct tgccattgac tttcaccacg ctaatcaagg aattggaatt gtcatcccaa
    17701 attttcttta attcacccga tgaatcagtt tcattttcat aattatagag ctgaatatcc
    17761 atgtccccaa actgaaaatg agcatcccct tgtgtgatat tttgaataac tgaaacacct
    17821 ttttctgcag cagtctgtaa aaccttatca tagccataca gattatccca tagacgttca
    17881 gaattagtaa tacgactatc actatatttc ttaagataga ctcggtcaac tggataggta
    17941 gacagtaatt catcaacatt tccaatatga tcactgtggg tatgggtcac caaaataaaa
    18001 tcaagttttt ggacacccaa ttccttcaaa cgacgaaaga cacggtctgt tagaacatgc
    18061 ttataagacg tttcaattcc ttctctccat ggatagcgag aatcacttcc atctgggaaa
    18121 tcataatctt ctcctgtatc caccatggca aaatgtccat tgctttcaag aataatcgca
    18181 tcactgccac cttcttgaac attgataaag tggattttat ttcctgaact ttcttgagcc
    18241 tgaacattcc cataccatga caaacctaaa aaagcgccta caagtgctaa actagttaat
    18301 ttctttttca ttcttacttt ctcaatctct ccaaggtttc cttaaaaatc tctgggatat
    18361 ctgctttaaa ttccaaggtc ttacctgttc tcggatgagt aaaacctaaa gtcttggcat
    18421 gaagaaattg tccatgtcct ttcaaagtct tgcgaggacc atagacctca tcaccagcga
    18481 ctggatggcc gatataagcc atgtggacac ggatttgatg agtgcgccct gtctccagtt
    18541 gcaactctac taagctataa tcgccaaagc gttccaagac gtgaaaacgc gtcactgcag
    18601 gcttcccttt agcagttaca gcctgtttct tacggtcttt ttcactccgg ccaatcggcg
    18661 cttcaattac accacgatca ttaggtagat ttccatgaac aatcgcccaa tatttgcgga
    18721 gagacttttt atccttgagt tcttgggcaa gtgctagatg cgcatcatcg tttttagcaa
    18781 tcatgagaag acctgacgta tccttatcaa tacggtgaac aatccctgga cgcagaaccc
    18841 cattgatacc cgacaagtcc ttaatatgat acatgagggc atttactagg gttccactgg
    18901 tatgaccagc actcgggtgc acaaccattc cctgaggttt gttaacgaca gccacatcct
    18961 catcttggta gactatttct agcggaagat cctcagccac atactctaat acctctggtt
    19021 ctggcacatg gtaagtgacg acatcaccct cttggactgt gtatttagct ttcttgactt
    19081 gaccattgac caagacctgg cctgatttaa tttgttcatt cgcgagacta cgtgataatt
    19141 ctgacaaatc tgacaaagcc ttatccaaac gcagaccacc agtttcaatt ttaatttcca
    19201 tttatttcct cttttagcat tgcaatcaat aaaataatca ctccaaccgt cagatagcta
    19261 tctgccacat tgaaaattgc aaagttgata aagtcaaggt ggaacatatc cacaacaaag
    19321 ccctgactga ccctgtcaat aaagtttcca agaccacccg cgattattag agtcaaaccc
    19381 aagaccatcc agaatgagtc ctccatgtgt ttatgtaaat accaaatggc acctatcacg
    19441 acaaccagag taatgacagc gaataacaac tgctgatctt gtaagataga aaaggctgca
    19501 cctcgatttt gcaggtaggt caagctaacg aaattgggga tccaggagcg cacttcaccc
    19561 agtggaatct gctggacgat ataggatttg accaactgat ccagcccaat caaaagcagt
    19621 acaatgactg ccactattgc tctttttttc atgatttcct cttttgatca aaatattctt
    19681 gcatgacttc tacgaagaga gtcccagctt gactaagctc cacttcttca cgtttaacat
    19741 agaccatgcg gttatctagg ttatccttga gacgaataac tgtaatgcca ttaacactgt
    19801 cactatctaa aaatccagaa cctgtcgcat aggcgtccgt ccgctccaaa ataccattca
    19861 aggtggcacg gtctgtcaca ttaaacatct gtgagctagc gctggtatca acaaagttct
    19921 ctgaataata aaggtactcg tctttctctt gagtgaaacg aaccgttggt aaatccgcta
    19981 aatcctccat gactaattcc tctttctggg ctaaaggatg accctcacag agataaatat
    20041 gggtatggaa aggaatcaat tcgatgacct ccagacctaa cttttcaacc cgttgcataa
    20101 tccccttttt attttgattg ttgaggtaga taatcccaat ctcactatgc ccttgcgcca
    20161 cttcatctaa tatttgaaca gtagttgatt caaaaatacg gaagttctta tagtcaggat
    20221 agcgctctga aaaggccgta atagttggtg gtaagaagtc atagtgctgg ctagcaacgg
    20281 aaaattcatc tttttcttct tcaggattgg catactgatt ttgaaaaata tcaaatcctt
    20341 taaccaattc ttgcgctttt tcataaaatt ccatcccacg acgggtcaag aaagtccctg
    20401 agctggtccg acggaaaatc ttaaaaccca actctttttc caaatcccga acagaaatag
    20461 acagactcgg ctgactaaca tacatctttt cagcagcttc acgaaaagta ccactattgg
    20521 caatagccac aacatagcgt aattgttgaa tgttcatctt ctacccctaa cttctttatc
    20581 ttttcattat accatatttt agaagttttc caaaaaggaa aaaagaacat cctattcttc
    20641 ttaactatct tcactatctg cctttctcac gccaatctta ttttcaaaat caattcaaaa
    20701 aaataagtgg ctacacacca cttcagtatc ggaaagaaaa acgttgacta tttgtgaaaa
    20761 aagaaaatgc cggaaaattc cgacattttt ttagtaagct aacttcctga aaataggagt
    20821 aaccaaacat cccagaaggc agtgatattg atgagaatat gaactagtat tggatagtag
    20881 agatttttag tcatgcgata caatagagct aaaatcagac ctccactagc ataaatgaaa
    20941 aaagcaagag gagttaaagc aaaattgata tgaatataac cgaaaataat agcagaaagc
    21001 aaaacatctc cgtaccaagg tgagtttttg aaaaaggttg tcataagcac acctcgataa
    21061 atcaattcct cagcaatagg ggcgatgaag caaacgatga gcaagaaata agggaactcc
    21121 tgtctcccca tcatttctat cgtttcattc aaagaaatct gatttgaaga cagggatatg
    21181 aaatacgaaa agaggaagtc agacatatat gaaatgatgt agcccagtaa aaggtagatg
    21241 aagtacctca gctgccactt gaaatgaaaa attttctttc ctgcaaaaac cagtagatag
    21301 atgaccgcta agaaaagaac tccgctctcc atcaaaagca gaatctgaaa aaattcacga
    21361 cttgctggta gatagggctt tgcgaggtga ttgaaaactc tccaaaacca agttgatttg
    21421 taaaaaatta aggacaatgc tagtaaaatt tgaatagccc gttttttcat attaaattct
    21481 ctgctttctc cccttgtttc ttcatattac taataaattt tacttaaaat ctcgcagcac
    21541 ttcctttgca aagatgattg cctcctccaa tatatcctaa atcataggtg cctctgggac
    21601 aaaatccatg aaccggcaga gttaatactg gttctatttc ccaatcgtac ctaccattag
    21661 gatttttacc atatgaatct gctccacctt gtatcagctc taattcttca tttgttagat
    21721 ttatattttt tgtcattaaa atcatgatat atttcctcca ttattcttca gattagttga
    21781 gtaatctgat actcatacct acttacaaaa aaactattat attaagttgg ttttttaatt
    21841 tgtctagttg caacattgac aaacatagta tagcatatct ttgcgaaata tcctcttcaa
    21901 atcatgaatt gtcatcaaaa catcttaaac tataaaatca attagtctca agctttctat
    21961 caatttcttc tccaaaatat gctataataa tagcaaaaga taaagaagga agacctatga
    22021 ttaaactact agccttggat atggacggca ccctcctcaa tgaagccaag gaaatcccac
    22081 aagctcacat tactgctatt cacaaagcca ttgaaaaagg tgtcaaactg gttctctgta
    22141 cgggtcgccc ccttttcggt gtcctcccct actacaaaaa actgggactc gacctccaga
    22201 atgagtatgt gattgttaac aacggttgtt caactcacca gactagcgac tggggcttgg
    22261 ttgactggca agaacttagt ccagctgaca tcgaatacct ctatgacctt gctgaaaaga
    22321 gtgatgttca gttgacactt tttgacgagt cacattattt tgttctcggt ggaaagccca
    22381 atcaagttat tgaaaatgat gctaaactag tattttcaga cctgactgaa atttctcttg
    22441 aggaagcgac tagtggaaag ttccggatgt tccaaggtat gtttttagga acaaaagaac
    22501 aaacagacga ttttgagcag cgttttgctg aagagctttg ccaacgattc agtggagttc
    22561 gttcgcagcc tgtcatttat gaagcaatgc cacttggaac gacaaaggct actgctcttt
    22621 cacgactagc tgagattttg aagattgatt cctcagagat tatggccatg ggcgatgcta
    22681 ataacgatat cgaaatgctc cagtttgcag ggcttgggat tgcaatggga aatgccagcg
    22741 attatgtcaa atctcttgcg gatgccgtta cctcaagcaa cgaagaagac ggcgttgcgc
    22801 gtgctattga gaaatatatt ctataaaaaa gaaaagcaaa tagacagaag ttactgctat
    22861 ttgctttttt gctaatattt taaaatacgg actaatcaat agagaagaat agcgaatcat
    22921 aaaaatcgat ttactagatg ccatagtatc ttatagttgc taataagaag ttagtctagc
    22981 agaatgaatc tctcatttct cccacactaa tctgtaattt gtctatacat ttctggtctt
    23041 ctatctcgaa acaagcccca gtttaggcgt tcacttgctc ccttgtctag gttataagta
    23101 gctaacagaa cagcttcttc ttgtctttca gctcgttcta gaatagctcc tgtttcatcc
    23161 gtcataaagg aggaaccgta gaagtcaaga ctggaactct gtccgccatt ttcctcacta
    23221 ggagtaacct cctctaaacc ataacgattg gctgcgatga ctggaacaat attcgctgct
    23281 gcgtgccctt gcatagtacg ttgccagtga ccacaactat ctgtatccaa aatcggctct
    23341 gaaccgatgg ctgttggata aaagagcaat tcagcaccat tcaatgcaag acagcgcgct
    23401 gtttcaggga accattgatc ccaacagata ccgataccaa tcttagcata gcgagtattc
    23461 cagaccttga aaccagtgtt accaggcgtg aaatagaatt tttcttgata ataatggtca
    23521 tctggtatgt gggtctttcg ataaacgccc agcacttccc catctgcatc aatgacggca
    23581 atagagttat acaagacatt accatctttt tcatagaaac tgattggtaa aacaacttgt
    23641 agttccttag caatcacctt aaaatgctga atggcagtat tttccgctac agattgggca
    23701 tactggtagt agtcatactg acgttcctga cagaaatagg gatgttcaaa caactcgggc
    23761 aagagaataa tttgggctcc ttgctcagca gcctgacgta ctaaacgctc tgcggtttgg
    23821 atatttgttg ccacatcctt agcgcattgc atctgaatgg ttgcaactct tacatttctc
    23881 atctttttct cctattctgg aatttgttgg gtgatacagt ggatattgcc accacctaag
    23941 agaatatctc tggctggtat tccgacaact ttacggtctg ggaaacactt gctgaggata
    24001 tctaaggcca cttggtcgtt tacatcctca aactgtggaa ccaagacagc cttgttggcg
    24061 atataaaagt ttacgtagga agctgctagt cgttcacctg cgtatcgctt ttcttctcct
    24121 tcttcataga tgtagcctgg caaatcttct tctgtcacaa cttgtcgaac tgcagggata
    24181 ggcaatttat gaatggtgaa gtgacaacct tttgcatctg tttcctgttc taagagttcg
    24241 agatctgctt ttgacatggc atactgggga tcattttcgt catctgtcca agccaaaaca
    24301 agctcagcag gaccaacaaa ggcagcaaca ttatcgacgt gttcattggt ttcatcctga
    24361 taaataccat aaggaagcca aataactttt tcagcaccaa gactttctaa taatgtgttt
    24421 tcaatctcct ctttagtcag gttaggattg cgaccaggac taagcaagca actttcagtt
    24481 acgagaatag ttccttgacc atcgctatgg attgcgcctc cttccagtac aaaaggttta
    24541 gcatcataga caggcctttc caaggcctca gcaaaacgac tggctacttg gtcatcctct
    24601 tcataatctt gataaagacc atcataggtg cctccccaag cattaaaggc ccaatccacg
    24661 gctaatttct tacctttatc attgacgaga atggttgggc cagtatcacg cgcccaggca
    24721 tcattggtgg gaatgtctaa ataaacaacc ttgtctccaa gataggattg ggcttcagat
    24781 agataggcct gctccaccaa aagatagact ctttcccctt ctgctatggt ctcgatgatc
    24841 tgagtaaatg ctcttttagc agcctttcct tgaaaaggcc atgatcctgg tcgagtcggc
    24901 catatcatga gggtaccatg atggggttcg tactctgctg gcatgtgata gcctaatttt
    24961 tttggactgt ccatcatgat aatctccctt taaagtcttg atagccaaaa gctttgagta
    25021 agctacagtc tccctgttcg tccatgagat agagacttgg caatccaata ccattaaagg
    25081 tattattttt gacaaaagaa taaatggcca tgtcttgaaa ataaagtctg tctccgattt
    25141 ggactggatt ttcaaaacta taatcaccaa tcacatcgcc cgtcagacag gtattagaag
    25201 aaagtctgta ggtatgggct ttttcctgtg actcaaagcc atttctcaaa ggtggacgat
    25261 agggcatctc aagtacatca ggcatatggc aggtcgcaga ggcgtctaaa accaagattt
    25321 ccataccgtt ttctacaata tctaatacct cagttgctaa ataacccgca ttaagcgcaa
    25381 tggcttcacc aggctcgata tagatttcaa gattgtaagt ttttcggata cgcttgattt
    25441 ctgaaatcag caaatccaca tcgtaacctt ctcttgtaat atgatgacca ccacccatat
    25501 tgagccattt tacctcatgt aagtagggac caaactgttc ttctactgct ttcaaagttg
    25561 tttgtaaatc atctgctccc tgctcgcaaa gggtatgaaa atgaagtccg tcaaccaaat
    25621 ctagcaaatc actcggaatc ttgtctatag taactccaaa gcgagaacct ggtgcacaag
    25681 ggtcatagag cgcgtgatct ccttgagttg aacactgagg gttgaggcgc aaaccaacac
    25741 tgacaccagc ctctcgacaa cgcggaccgt gtttacgcaa ctgtctctct gagttaaaga
    25801 cgatatggtc cattatctct agcaattcct ccaagtctgc atccttgaaa gcaggcgcaa
    25861 atacatggac ttcaccagga aattcttccc ttgccaattt ggcctcatag agtccactag
    25921 ctgtcgtacc tgatagatac tggctaatca agggataagt tttgtagagg gaatatgcct
    25981 tctgggcaag caagaccttg caaccggcct cttcttgtac atattgtaga atgcggcaat
    26041 tagcttctaa cttggccaag tcaataacat aggctggtgt tggtacttgt tctaacttca
    26101 ttagtccacc atttgtggat tttcaaccac aacccatggc aaaccatact cattcaaagc
    26161 ttccatgaat ggatctggat ctaactcctc aaggttatac actccagctt gtttccaagt
    26221 tccgttcatg actaattttg tcccaatcat ggctggaact cctgtcgtat aagaaatagc
    26281 ttgcgaacca acctctgcgt aacattcctg atggtcgcag acattgtaga tatagatagt
    26341 ctttttgaca ccgtctttga cacctgtaaa gatacatcca atattggttt ttccgactgt
    26401 acgtggccca agactggcag gatctggaag caaggctttc aaaaattgaa ttggaacaat
    26461 ttcttggccg ttaaagttaa tggtatccgt acgaaggagt ccaacatttt caagacattt
    26521 catgtgcgtc aagtaagatt gaccaaaagt cataaagaaa cgaatgcgtt tgacacctgg
    26581 aatgttcttg gccaatgatt cgatttcttc atggtgaagg agatacatat ctttttgtcc
    26641 aacttgaggg aaatcatact cacgcttgat agacatagct tcgacttcga cccatttccc
    26701 atcttcccag taagaacctg gcgcagaaac ctcacggaga ttaatttctg gattaaagtt
    26761 ggttgcaaat ggataaccgt ggtcaccgcc attacagtct aaaatgtcga tataatggat
    26821 ttcatcaaaa tagtgtttga gggcataagc tgaaaagaca ctagttacac ctgggtcaaa
    26881 accagaacca agaagagcag tcaagcctgc ttctttgaat ttctcttgat aagcccactg
    26941 ccatgagtag tcaaagtagg ctgtaaaacc aagttcctta caacgttttt cgtagatagc
    27001 acgccactca gggtcttctg tgtcttctgc ttcgtagttg gctgtatcga tatagtgaac
    27061 acctgttgcc aaacaagcat ccataatggt taaatcttga taaggcagag ctacattcaa
    27121 aacagcttct ggtttgtagc tttcaatcag ggcaatcact tcttcaacct tgtcagcatc
    27181 aagtgctgca gtttcaattt tagtacttgt tttgccttct agcttcgctt tcaagtcatc
    27241 gcattttgac ttggtacggc tagcaatcat aatctctgta aatgtttcgc tatcttgaca
    27301 aatctttgaa atagcaactt gggcaacgcc cccacaacca ataactagta aacgactcat
    27361 ttttttcctt cctcttcttc taaaatgtcc tcaacatact tgggcaacat aaaggctccc
    27421 acgtgtaagt ttgcagtgta gtattctgtg aaaagctggc gttttttcca gccttccttg
    27481 tcaaaatctt tgacagggtg gtattttttc gatgcaaatc caaacaacca atagccagct
    27541 gggctagttg gaatatgggc ctgataaacc cgactgattg gaaaggcttg attgaccttg
    27601 cggtgcatgc ttcggcaggc cgactcatcc tcgtcaaaga agggactccc atgctggtaa
    27661 atcatgatgc cgtcttcctt cagagctcga taactattgc cgtagaattc cttggtaaag
    27721 agtccttccg tatggccaaa tggatctgtc gcatcgttga tgataatatc gtaatcatct
    27781 tcgcagtttc gcaaaaagcg tagcccattt tggtagtaaa tggtaacacg aggatcatct
    27841 agccctgcag caaagtctgg gaaatactca cgacagacct cgaccaacat ctcatccggt
    27901 tccacaatat caatttgctc cagttcagga tagagggtta atacttgggc aacaccgccg
    27961 tcaccacccc caataaccaa tactttcttt ggatttgggt ggacagccat gggaacgtga
    28021 acggtcattt cattgtagac gaaatcatcc gcatctgaga acaagacatg gccatttaaa
    28081 atcagtattt tcccaaaagc tggcgtatcc aagacttcga tatcctgcca ttcacttttt
    28141 ccagcgtaaa gttgcttggc tgttctcaga gacaatttga catctggagt atgaacttca
    28201 gaaaaccata aatccatcta tttctcctta tattatattt agcgcagtta gctactgcca
    28261 aagcccaagt ggtatacttg gaataagcca ctgtggatta gttcatttcc tccaatcgct
    28321 tgacgatttc cgaaaggctc taaccacagc ttttgtttca attggtaatg agtttgataa
    28381 cgcatagacg ttttatctcg tctaaggtaa caaggcaaaa agttcgtgga taaccaagta
    28441 gacttgaaat actacatctg gaggtactcc catgctttat gtgggcattg atatcgctaa
    28501 aaataaacac gatgttacag ccttgaatgt tcaaggaaaa actgttctta aaccactcac
    28561 tttttcaaat aataaagctg gttttgaact cttagatctg tctcttcgac agctcaacca
    28621 agactgtctc atcgctcttg aagatactgg acattatgcc tttaatctac tgaacttcct
    28681 gcatgaacaa ggatataaag tttacaccta caatcctttg ctcatcaagg aatttgccaa
    28741 atcattatca cttcgcaaga ctaaaacgga taagaaagac gctcatggca tcgctcttaa
    28801 acttctttct gaccccaatc gtgaacaatt tcaacacgat aatcggcaag tagaactaaa
    28861 aatactggct agacatattc atcgtctcaa gaaaaacagt ctgattggaa agtacaatac
    28921 actcgttgtc ttgatatcat ctttcctgag ttggataaaa tcgttggaaa gcattcagaa
    28981 tatacctacc aactcttgac acgctaccct aatcctcaga aaaggattga ggcaggattt
    29041 gataagctga tagaaattaa gcgattgacc gcttctaatt caagggcttt ttgccgtgct
    29101 ctaaaatcat cgccaaatca tcaaattgaa ataagaaata gtttagataa aactattgac
    29161 ttttcttata gtttgtcttt ctcttaataa cgttgatatg attgacctct ggatcttccg
    29221 tcccttggag ggagcaacca cgttccttgg cgaattggat atagtctaca atttctcgtg
    29281 taatgcgttc accaggagcc aagataggaa tccctggagg atagcacatg acaaattctc
    29341 cacagacctg tccaacagac tcatctaagg tcaaactttt tctctctgaa tagaaggctt
    29401 cttgtggaga cagcaccaac tcgggctgaa tatattctcc agctattaag tccttcccat
    29461 ctcgtgaata gagtctctta atatcagcca gagcaccaac caagcgctcg atgtcttgga
    29521 tgcggtcgcc gatggaaata taggccaaga tattgccgat atcaccaaac tcgatctgaa
    29581 tgtcgtattc gtctcgcaag aggtcataaa cctcgatacc tgttaagcct attccctgag
    29641 tgtaaactga caacttggtt acatcaaaat cacagaccga cacaccatct attaactctt
    29701 ttgagtaagc atagtaaccg ccaatggcat tgatttcatg acgagcgtac tcggatagct
    29761 caatgacttc ctcaaacgac tctttaccac gaagggccaa gttgcgacgt gaaatatcca
    29821 aactagccat caataagtaa gaggcagatg tagactgggt caggtttata atctgacgaa
    29881 cgtactcggg attcatctgc tccccgatta aaagaagcga actttgtgtc aaactcccac
    29941 cagacttatg catggaaact gctgccatat cagctcctgc atccatagca gaaattggaa
    30001 gtttaccagt gaaatgcaaa tgcgctccat gggcttcatc tactaaaacc atcatgccag
    30061 cttcatgagc catttctgtc aaccccttta ggtctgaaca gatgccgtag taagtaggat
    30121 tgttgattag gatagcctta gcatctggat ggtcctttat ggcctgtgct actcggtcat
    30181 tttcaagacc taaagcgata ccaatcttag gatctacact catctcgata tagatgggaa
    30241 tggcaccaca tagaaccaac gcattgatag cagatttatg gacatttcgt ggcagaataa
    30301 tcttatctcc tgccttgcag gttgccagaa tcatagtctg caccgatgaa gttgttccac
    30361 caatcattag aaaggcatgg ctagctccaa aagcatctgc agccagctcc tctgcatcac
    30421 gaataatcga aataggatgg cctaaattat ccaagggttt catcgaattg acatcaatgc
    30481 ctacacattt ttctcctaag agttcgacaa gttctggatt tccccgtcca cgcttgtgac
    30541 ctggaacatc aaagggaaca atccttttct tgcgtaactt caccaaggct tcataaattg
    30601 gggcttggtt ttgatctaac tctttcaaaa catactcctt tcaatatttt taggacctta
    30661 tgaaaactaa ggaactaaag gttgactcat gaaaaaagag caggttttca cctgctctgc
    30721 aatcttctga cgtgtttatt ttggtttctg ttgagtatgt ctgttcccga tgtttcctaa
    30781 ctctctagta gcaaatatta cgtactttat tgatcgtttc acaagatgac gtgtgctttc
    30841 accacactaa aaatttatga attaggacaa gtgtcctaac atcaacttat aaaagtaggc
    30901 ttttaaccct atcaataatg tggcttttca accacgcttc ggcattcaac cctgcctgtc
    30961 cgtaggcatt ttttactcgg gtttatattt gctagaaaac atcatctcat tttctaagct
    31021 ttattactat atcatgtttt taagaacttg taaagtattt tttgataaaa aacaaaaata
    31081 tagtagattg aaactagaat agtacacttc tgcttctaaa acattattag aaatagattt
    31141 tactgtcctg atcgatttgt tctgttcttg tttcatttta ctatatgttc gtaaatgaaa
    31201 gttctataat gaagttagcc acccagccct cctaaaaatt agatggttca actagctgat
    31261 agctcttgta ggcataagaa aacacctctg tgttatactt gttgttcaac cacaaacaca
    31321 agaaaggcac agagatgcaa gacaattata ctacaaaagc caaacatttg acaatcgata
    31381 gccgtcgctt aatcgaaaga tggaaaaaag aagggaaatc aaatagagaa attgcctctc
    31441 tgcttggaaa agttcctcaa actatccaca ctgaaatcaa gcgtgggaca gtccgacaat
    31501 gtcttggaaa agggcgcttc aaagaggttt attctgccga ctatgctcaa cagtcttatg
    31561 aaaacaatcg caagcgctcg gtcaggaaat caagcgtgac caaggaacta aaggaaaaga
    31621 ttctccacta tcataaccaa aaattttcgc ctgaaatgat ggtgatggtt aaaggggtta
    31681 acgtgggaat ttcaaccatt tactattgga ttcatcatgg aaaattgggg ttaagcaaac
    31741 aggatctgct ttaccctaga aaaggaaaag cgcttaagaa acaggctagc accaacttta
    31801 aatctgctgg tcaatccatc gaacagcggt ctgaagctat caatcttcgc ttggagaatg
    31861 ggcattatga gattgatacg gttctactta cgagagcgaa aaactactgt ttgcttgtct
    31921 tgacggatcg aaagagtaga catcagatca tccgattgat tccaaataaa agtgctgatg
    31981 tggtcaatca ggctctaaaa ctcatcttaa aacaacacaa gattctttcc atcacggcag
    32041 ataatggaac ggaattcaat cgcttgtttg atgtattttc tgaggagcac atctattatg
    32101 cgcaccccta tgcctcttgg gaaaggggaa ctaatgagaa tcacaacagg ctcattcgta
    32161 gatggttacc taagggaatc aagaaaatga ctcccaaaga agtcgcattc atcgaaaagt
    32221 ggattaacaa ctatcctaaa aaatgcttgg actacaagtc acccagagaa gacttctgga
    32281 tggctaactt gaacttgaaa tttagcgtca gaaacaaatc acgaaattga ttcaaatttt
    32341 gcaggtcgtt taaatatcct gcgtgcgggt gttcttgatg ctaacgatgg aattatttcc
    32401 attgctggtg tggttatcgg agttgccagt gccacgagca atatctggat tatcttttta
    32461 tcaggttttg cggctatctt agctggtgcc ttttcaatgg ctggtggaga atatgtatcc
    32521 gtttcaactc caaaagatac cgaggaagct gccgtttcgc gagaaaaact cttgctagac
    32581 caagataggg aactagccaa aaaatccctc tatgcttctt atatccaaaa tggagaattc
    32641 aaaacttctg cccaactctt gactaataag atctttctta aaaatccact caaggctctg
    32701 gtagaggaaa aatatgggat tgagtatgaa gaatttacca atccttggca cgctgccatt
    32761 tctagcttcg ttgccttttt ccttagaagt ttgcctccaa tgctgtcagt gaccattttt
    32821 ccaagtgatt accgcatccc tgctaccgtc cttattgtcg gtgtggccct tcttctcact
    32881 ggttacacaa gtgctagact tggaaaagcc ccaaccaaaa cagctatgat tcggaacctt
    32941 gctattggtc tcttgaccat gggagttacc ttcctgctcg aacaactttt cagcatttag
    33001 aatacaagaa atacctcgat tttgaagtcg aggtatcttt tttacatttg cacaatcttg
    33061 cgataacttc ttgaagtaat cataaaaatc agcacatagg cgatgaggaa gatagcgcag
    33121 atagacaagg tcacaatcaa catcatagtc gtatccagta caccaatcac ttttaaaatc
    33181 aggctaagca tatggtaggc aaaggctaga tgtaggaagg caaagagcaa aggaaggaag
    33241 aaaacagtta aaacctgttt gttgatggtt tgcttgattt gcttttggtc caaaccgact
    33301 ttctgcaaga taataaagcg ttcacggtct tcgtagcctt cagaaatttg tttgtagtag
    33361 atgaccagaa cagttccgac cataaagata atggatagga aaataccgat aaagaagaca
    33421 ccaccaaaga gggcactcat ctgagcacta gcatctgcta gagtgctacc ataaacatag
    33481 ctaccttctg tgtctaattg agcattaaat tgattgaggt agttttcata ctcctcagcg
    33541 accttgagtt gttcttcttc gctggcatct acattcatac caccgtaaaa ctgattatag
    33601 atagccgaat ctgggaattg atccaaaaag gcttgtaaat caggaacaac aaggtaattg
    33661 taatcagtag tcaagatatt aaacttattt ggaacatggt tgacaatgaa atctttatta
    33721 aattcttctt tgacagaaaa ttgatgatca tttagagtta gagctttctg tcctttcagt
    33781 ccgtcatttt tggcaaagag accgacctca tttcctgata gagacagttt ttgaccagtc
    33841 atattttcat aatctttttg gtcaaatacc atgaaaactg tttttggttg gacacggttt
    33901 tgtccttttt caaaaatagt taacttggtt ccttcttgat ttgcaatacc aaagttactg
    33961 taacgaagca cttctttctc tttaatctta taacctttgt cacttgcaaa ctggctcaag
    34021 agtttgtcca aatcttcttt ttcaacattt tgccctgaaa ccccaaaatc atgaggattt
    34081 agaacttttt taaaggattc tgcggaattg aaaatgcttg tcgctgctga catggttacc
    34141 aaaaccattg ttgacaaaat agcgatagtt gctagtccaa ctgcattttt cttcatacgg
    34201 aaaatcaagt tagaaacaga tatgagatta ttaggttggt aatagtattt cttatttttc
    34261 tttaagattt gaaggaaaac ggtaatccct gcattgaaca aaagataagt accaaagata
    34321 accagtaaaa cagctatgaa gaaggttgtt aaggctgtaa gaggatcttt taccgtaagg
    34381 gcaagataat atccaatccc taaacttatg gaaccaagaa tagtttggag aggaaggaag
    34441 cgaccttttt tctctccgct agctttctca cgtgagagct ggagggcatt catacgggcg
    34501 attcgaaggg cattcaggaa catgaggcct aggaaaatca aaccgaagac aagaagtact
    34561 gtaatgacaa ctttcatctg gaaggtagcg accagttcca ccttcaattt catcagtttg
    34621 agtaggaaag cgaaaatcaa cttgtcaaac aaggctccaa taccgatacc cgctccaaca
    34681 gttagaatcc caaataccac taactcctta aaggtcatac tgataagatg acgcttctcc
    34741 aagcccaaca tgccataaat tcctagttcc ttggaacggt tcttcatgac aaaactattg
    34801 gcatagagaa cgataatggc tgacgcaagg gtgacgacaa acataccaaa tccaagtgta
    34861 gcctgaatgg ttgttcctcc acggatttcc gcaatcttag gattgaaggt tagagagtaa
    34921 aagagatagg tgacagtgac tgccaagaga acagccagcg caaaaggata gtagagtttg
    34981 cggtttttaa tcaagttcga taccgctaac ttattggtta atcgaaacat actaattcac
    35041 ctcgcttgcc atgacagtca aggtatcaga gatttcttgg aacatctgac gttctgtctt
    35101 ctctccacgg tagatttgat tgtaaagaat gccgtctttg ataaagagta cacgtttagc
    35161 tctgctagct gctgctgttg agtgggttac catgagaatg gtttggccgc gctcattgat
    35221 ttcatcaaag acatcaagta aggctgcaga tgacttggag tcaagagctc ctgtcggttc
    35281 gtccgcaagg agaatttcag gttctgtgat gatggcgcgg gctactgcta cacgctgttt
    35341 ctgaccacca gaaatctcgt aagggtactt ctcttgtaat tggtttattc ccagattctc
    35401 agctgtcacc accaatttct tcatcatctc tgtaataggt cttcttgaca agacaagcgg
    35461 aagcaagata ttgtccttta cagatagagt atctagcaag ttaaagtctt ggaagacaaa
    35521 gcccaacttt tcacgacgga agctagaggc ctgtgaattt ttaatggttg cggtgtcagt
    35581 tccattcaag taaacctgac cacgacttgg tttatccagc atagctagaa tattgagaag
    35641 agttgattta ccagaaccag actcacccat gatggcaacg tagtcaccct tttcgacggt
    35701 aaagtgaata tccttgaggg cttctacttg gttgccctga aaacgtgttt tataaatttt
    35761 ttgaacgtgt tttacatcta aaagtgtcat gagaatctcc tttcttaata tcccatcaaa
    35821 tgaaatgtag cttgcatcat agtgcatccc agctgaacgc gctcaatttc tttgtgactt
    35881 ggttttctag ttttcttatg taagatttgt ttcatgatgt tactcctttg ttctttatga
    35941 gtctagttta catcaaaaaa agaccgcttg ccataaccta accttacaaa agagacttta
    36001 atcttacatt tttgtaagat tgggtgaaat ataagcaaaa ttacttagaa aatgatttga
    36061 tttcctattt ttaaagttgt aaaatataag tgtgaaaagg cttactttga aaaggaggaa
    36121 gcgggaacta acattttagt aaggttacct agataacata ccattcaatt taacacttgc
    36181 aagtcgttca acctataagg aaagaaggtg cgctttaatg aaacacaaag aacatatact
    36241 catcggactt ctctatctgc tctctccatt catcggtcag ctcttagttg aacacacaca
    36301 ctttatcggt acagaattta ccggcactgc ttatgttatt tgctggttat cagttgttat
    36361 cagcatccac catttttcca aaaatgtatt gtctcaacag caaaaataga ttaaaaaact
    36421 gcgtttaaat tactgctttt atagtaaaat gaaataagaa caggacaaat cgatcaggac
    36481 agtcaaatcg atttctaaca attttttaga agtataggtg tcctattcta gttccaatcc
    36541 actatagttt gtggatgaag ctggcgaaat attattaata ctattcaaaa atcaaagtgc
    36601 aaactatatc aacttcacat tgccgactaa attacagcct gcggctggct tcctagtttg
    36661 cactttgatt tttattgagt ataaaagtaa aaaagcttta aatcaagcag tttagactat
    36721 tgatttaaag ctttttgcgt attccaaatc ttttgtaaaa cctcaccaaa accagccttc
    36781 attatcgtca atggcttgag cttctttgcg tttacgtggg cctgttccgt acatttctgc
    36841 ttcgatttct tccttggttg gcatgataga agctaggatg atatagataa tcaccccaag
    36901 tccaaagttt gcgactgtaa aaatggcaaa cagaaaacgt acaagggtaa catcaaagtt
    36961 ccacttgtct gacagacctg ctaaaactcc tgaaatcatg cgatttcgtc tcattttata
    37021 aaacttactg ttcatgatat ttcctctttc tgctaggtta gactagtata tcacggatag
    37081 gctcggcttt catcagtcct caggctgatt tactaatagc aactttcctc gacaaagtcc
    37141 acagcgatag cgttgggtat caatcctacg cttacgctga taagtttgct ggcaggattg
    37201 gcaacgatag agcttgattg gcttggagtt actattgggc aaggatggta caaaccgtaa
    37261 tccatccact gctttcaaca gttccttaaa atcccgatcc ttgtgttgat agcctttccc
    37321 ttgaaaatag aggtgataat gacagagttc atgtcggaca attttcctaa aaacgtccaa
    37381 ccccagttcc tgataaacct tgggattaaa atccaaatgc ccatctttgg ggaaaaatcg
    37441 cccacctgtc gaacgtagac gcctattcca ctggacatga tggataaaag gtctgccgaa
    37501 gtcttctagt gaaacctgct tgacgtaatc agtcagtttc atttggagct aggagagaca
    37561 gattaacttt ttcacgttca gtatcaattt tcttaaccca aacgctcacc aaatctccaa
    37621 ctgccaccac ttgactaggg tgtttgataa acttgcgact catatgggaa atatggatga
    37681 gaccgtcctc atgaattccg atatcaacaa aagcaccgaa atcaacaaca ttacgcacca
    37741 ctccttctag cttttgtcca accactaagt ccttgatatc taggacatct tgacggagaa
    37801 ctggagcatc aaaggaatca cggaaatctc gacctggttt gagaagatct gcaatgatat
    37861 ctttaagagt ttctggacca aggtctaact cttgcgccat ttccttgact gaaagcgact
    37921 tgagtttact ttgggcctct tcattcagat ccttaatgtc caagcatttg aagagttcct
    37981 taacggcagc gtaattttct gggtgaactc ctgtattatc aaggatattg ctactttcag
    38041 ggatacggag gaaaccagca gcctgttcaa aagccttggc ccccaaacga ggaactttct
    38101 tgatttggga gcgtgaagtg atttttccct cttcctcacg gtatttgacg atattttcag
    38161 aaatggtttt attgagtcca gctacgtgtg aaagaagagc tgggctagct gtattgacat
    38221 tgacaccaac ttggttaacc actgtatcga caacaaagtc cagactctca gatagtttct
    38281 tctgactgac atcgtgttgg tattgaccga caccaattga cttaggatcg attttgacca
    38341 attccgcaag aggatcttgc aaacgacggg cgatagaaat ggcagagcgt ttttcaacgg
    38401 tcaagtctgg aaactcctga cgagcaagtt cgctggcaga atagacagaa gcaccacttt
    38461 cattaacgat aacatagctg acttcaggga aatctttcag aacttccgct acaaaagctt
    38521 cactttcacg actggccgtt ccatttccaa tggcaataat ctctacaccg tattgaccaa
    38581 ttaaatctgc taaatctttc ttggcttctt cgatttgacg agctgatgct ggtttaacag
    38641 gataaataac ctgagttgtc agcatttttc ctgttgcatc cacgacagct agcttggcac
    38701 ctgtacgaaa ggctgggtca aacccaagaa ccacgcgccc tttcagtgga gcaaccaaga
    38761 ggagattgcg cagattgtca gaaaaaagtt ggatagctcc ctcttcagct ttctcagtta
    38821 attctgtccg aatacgacgc tcaatagcag gcaagacctt tttcttaacg gattgctgaa
    38881 caacttcatc aatataagca tttttcacct tgaaacgagt agcaaagaag gcaagaatac
    38941 ggtccgtcgc atgttcaaaa ccgatcttca agacaccaag tttctcccca cgattgagag
    39001 ccaaggtacg atagccttgc atagttccaa ctgtctctga aaaatcataa taaatctgaa
    39061 aaacctgctt ttcatcaaga ctttcatcct tggcttgaga agtgagttta gagtgtctca
    39121 gcacttcctg ataagtcata gaacgcaagg tcacatcttc cgataaggct tcgaccaaaa
    39181 tatcaactgc accggtcaag gcttccttgc cagtcgcaaa tccttcacag acgaactttt
    39241 cagcttcttt ctctaagtca actatattct gcaaaatcaa acgagcaaga ggaaagagtc
    39301 cagcttcacg ggcaatggtt gccttggtac gacgcttttc cttataagga agatagagtt
    39361 cttcaacgtc tgctaatttt tcggcaacta agatagcttc ttccaattcc ttggtcaact
    39421 taccttgttc ttgaatctta gctaagacag cttccttacg gtcattgaga tttgtcagac
    39481 ttttatccaa atcaataata gccttaatcg ccacctcatc cagactacca gtcatgtcct
    39541 tgcgataacg cgcgataaag ggaatagtcg ccccttcagc tgtcaaactt agaacggtat
    39601 caatttgctt taacgtcact cccaaatcct gagagatttt ttcatatttt ttatccataa
    39661 atctattata ccacaagcta aacgtttcaa attaactcgt agaacattta aaaaatatgt
    39721 aggaaataga tttatatgct acagcgcaat aacttgcact taaagagcat tgccaccttt
    39781 ttttaaccaa gccatgatat caaaagtatt taatggatca gacataatag ccagttctgg
    39841 aagatgttcc tgacctggaa taacacattg acttttcaaa tttttatatg gacgattgac
    39901 taaaattaat ttattagaat aaggaagatt atccatctta tttaaaattt cttcactagc
    39961 tgaatcttta ttatcaaatt taaaataaag attattccaa tttatgcgtt tttttctttt
    40021 ttcccactta gttcgtgctt cttcaatact agaataatgt agaaaatgaa tatctatatc
    40081 tcctaagtgc cccaaaggat aaacttcatg agtccagctc ggtgaaataa gttcctcttc
    40141 gaaaacaagt tcttgttcca tataataacg aaaatgcttt gtaagtttat aataatcatc
    40201 aggaagaata aataaaccaa caaaaggtgt tctatattga aaaccaagct gtttataaat
    40261 taatcctcca acacaattat tacttataat cgtaaaatct aatctatcaa gctcaagaaa
    40321 agggaaaatt cctttctctg cagctattaa cttatgataa acaatatcag aatctaaata
    40381 ttcaccgtca ttttttaacc aagcactaaa atttgccaat tcttgaatat attgtttttt
    40441 cgctctttct atatcatagt tttctaagac ggcgcaatct ttgattctat tttcataatt
    40501 ttctaatatg attttgtagg agtcttttag aggtttagca tctataacag gtttatagat
    40561 atatgtcggg aaattaatat aggttgcagt tttagagtga atataaagtc tccaaataag
    40621 gttgtttata tcaaattgat ttatttttcg taaaagctta ctattgaata attttccaaa
    40681 taatgagcga tattgttttc taattcgatg atctgtatca tccatctttt gtaaaacttg
    40741 aacattcgtt aaattttctg tcaaccaatt atcccccccc aaaaggataa aagtaaaata
    40801 ctccatcaac caaatcagca aaatgaccaa gaacaacatc agaatcggat aattttatcg
    40861 catgatacat cttttcaaat gtccaatcaa ataatgaatc atttgaagat agaaacgtaa
    40921 tataatctcc tgtaatcata tcagacaact cagcaaaaga attctcatct ataatcttaa
    40981 tattaaatga tagattcatc tgttggctaa tggaagctat ctcctctgta gattgattta
    41041 caataataac ttctatatct tttaatgttt gtctctccac tattgacaaa gactctaata
    41101 aactattttt atctccttga tgtaacaaaa caacactaat tgagtaagtc agtttgacta
    41161 cctcccataa ttttctgata atgattttct ttttatttaa ttatagcaca attatgatat
    41221 atatcaggta atatcaagct atattatctc ttagctactc aatttgaaat tttaactttt
    41281 cccttttccg caaaataata gtataataga ggtagaattt agaatcgagg tacacctatg
    41341 gctgtcaaat ttacaaaacg agacgacttg gacaagatgt ttgaagagtt tgctaaactc
    41401 cctgatttga aacaagttac tttccctgat gacaaagaga aaaaagtcaa agcagaaaag
    41461 aaaaactaga tgactgcttt tcaacaactc ccatctagtg tacttcaaac tggagccatt
    41521 tttctctcca ttatcattga agcccttccc ttcgttctga taggaagcat tgtctcaggg
    41581 ctgattgaag tttatatcac acctgacaag gtttatcatt ttctccctcg aaatcgttgg
    41641 gggagaatct tttttgggac ctttgtcggt atacttttcc cttcttgtga atgtggaatc
    41701 gtccccatca tcaatcgttt tctggaaaaa aaggttccaa gttacacggc cgttcctttt
    41761 cttgtgacag cacctgttat caatcccatt gttctttttg cgacctattc tgcctttggc
    41821 aactccttcc atgtcgccct attacgagct ctgggttcca ttcttgtggc tgtaatacta
    41881 ggaatttttc taggattttt ctggcaagaa ccgattcaga aagaaaatcg tctggcttgt
    41941 catgagcatg atttttctta cttgagttct gcaaaaaaag tttttcaagt ctttgtgcag
    42001 gccattgatg aattttttga tacggggcgt tatttggtat ttggctgcct ctttgcttct
    42061 ataatacagg tctacgttcc gactcggatt ctgacctcta tcagtgcgac tcctcttttt
    42121 gctatcctgc tcttgatgct tttagccttt cttctttcgc tctgtagtga ggcggatgcc
    42181 tttataggtg cttctctact ctcgagtttc ggtttggcac cagttctggc ctttctcgtc
    42241 attggcccaa tgctggatat caaaaatatt ctcatgatga aaaattactt gaaagcacga
    42301 tttattagtc acttcattac gattgtgact ctggtcgttt tagcctattc tctcttgatt
    42361 ggagtcatcc tatgattcga tttttagttt tagctggcta ttttgaactg actatttacc
    42421 tccatctgtc gggcaaacta aaccagtaca tcaacatgca ctattcctat ctggcctata
    42481 tctccatggt gctttccttt atcttggcaa ttgttcaatt gtatatctgg atgaagcaag
    42541 tcaaaaccca cagtcatctg aacagccgat tggccaagat gacgagtatt tctcttctgg
    42601 ctattccact tgtcatcggc ttaactttcc caactgttag cttggattct cagaccgttt
    42661 ctgctaaagg ttatcatttc cccctatcgg aaggaacgga tctagctatt cagacaagtg
    42721 aagggacgac aagccaatat ttgaaaccag atactagttc ttatttttca aaatcagcct
    42781 atgaaaagga aatgcgaacg gcggcggata aatacttatc ccaagatagt attcagatca
    42841 ctaatgaaaa ctatatggaa gtcatggagg ctatctacga ctatccagat gaatttgagg
    42901 gcaagacaat ccagtttaca ggctttgtct ataacgaccc cagtcatgcc aatagtcaat
    42961 ttctgttccg attcggcatt atccactgta tcgcagattc tggtgtctat ggattgctga
    43021 ccaagggcaa tacccggcag tatgaaaaca acacctggat tacagccaaa ggaaaactgg
    43081 tcaatcacta ccataaagaa ctcaaacaaa accttccaac cttggaaatc gacagcttta
    43141 ccaaagtcga taaaccagaa aatccctatg tatatagagc tttttaagaa aatcaagata
    43201 aaaacgaaca agttctcttc tgaataacag aaaaagagcc tgttcgtttt tttgttatat
    43261 gaaaattagt gacttgtaga ttggctcttt gtcaactgta gtgggttgaa aaaaagctaa
    43321 gctcgagaaa ggacaaattt cgttctttct tttttgatat tcagggcgat aaaaatccgt
    43381 tttttgaagt tttcaaagtt ccgaaaacca aaggcattgc gcttgataag tttgatgaga
    43441 ttattggtcg cttccaattt ggcgttagaa tagtgtagtt gaagggcgtt gacgattttc
    43501 tctttgtcct ttagaaaggt tttaaagaca gtctgaaaaa gaggatgaac ctgctt
//
LOCUS       DAVKEV010000019        40284 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVKEV010000019 DAVKEV010000000
VERSION     DAVKEV010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.019"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            19..89
                     /locus_tag="VWZ68_000989"
     tRNA            19..89
                     /locus_tag="VWZ68_000989"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:51..53,aa:Gly,seq:tcc)
     gene            124..197
                     /locus_tag="VWZ68_000990"
     tRNA            124..197
                     /locus_tag="VWZ68_000990"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:158..160,aa:Ile,seq:gat)
     gene            280..369
                     /locus_tag="VWZ68_000991"
     tRNA            280..369
                     /locus_tag="VWZ68_000991"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:316..318,aa:Ser,seq:tga)
     gene            380..453
                     /locus_tag="VWZ68_000992"
     tRNA            380..453
                     /locus_tag="VWZ68_000992"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:414..416,aa:Met,seq:cat)
     gene            457..529
                     /locus_tag="VWZ68_000993"
     tRNA            457..529
                     /locus_tag="VWZ68_000993"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:490..492,aa:Phe,seq:gaa)
     gene            542..622
                     /locus_tag="VWZ68_000994"
     tRNA            542..622
                     /locus_tag="VWZ68_000994"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:576..578,aa:Tyr,seq:gta)
     gene            627..697
                     /locus_tag="VWZ68_000995"
     tRNA            627..697
                     /locus_tag="VWZ68_000995"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:659..661,aa:Trp,seq:cca)
     gene            712..784
                     /locus_tag="VWZ68_000996"
     tRNA            712..784
                     /locus_tag="VWZ68_000996"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:745..747,aa:His,seq:gtg)
     gene            795..866
                     /locus_tag="VWZ68_000997"
     tRNA            795..866
                     /locus_tag="VWZ68_000997"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:827..829,aa:Gln,seq:ttg)
     gene            876..959
                     /locus_tag="VWZ68_000998"
     tRNA            876..959
                     /locus_tag="VWZ68_000998"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:910..912,aa:Leu,seq:caa)
     gene            1066..2343
                     /locus_tag="VWZ68_000999"
     CDS             1066..2343
                     /locus_tag="VWZ68_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEU9372035.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2419..3903
                     /locus_tag="VWZ68_001000"
     CDS             2419..3903
                     /locus_tag="VWZ68_001000"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEU9372036.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIALLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNMQGQYKLTDFDAEILELFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTTVAAADMQAAVEAYLGL"
     gene            3964..5244
                     /locus_tag="VWZ68_001001"
     CDS             3964..5244
                     /locus_tag="VWZ68_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU9372037.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5248..5868
                     /locus_tag="VWZ68_001002"
     CDS             5248..5868
                     /locus_tag="VWZ68_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU9372038.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6034..7176
                     /locus_tag="VWZ68_001003"
     CDS             6034..7176
                     /locus_tag="VWZ68_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU9372039.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQETTPGEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7582..7920
                     /locus_tag="VWZ68_001004"
     CDS             7582..7920
                     /locus_tag="VWZ68_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU9372040.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRHFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            7931..8289
                     /locus_tag="VWZ68_001005"
                     /pseudo
     CDS             7931..8289
                     /locus_tag="VWZ68_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
     gene            8396..9013
                     /gene="pcp"
                     /locus_tag="VWZ68_001006"
                     /pseudo
     CDS             8396..9013
                     /gene="pcp"
                     /locus_tag="VWZ68_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(9041..9898)
                     /locus_tag="VWZ68_001007"
     CDS             complement(9041..9898)
                     /locus_tag="VWZ68_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEU9372041.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVFFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10028..11170
                     /gene="tgt"
                     /locus_tag="VWZ68_001008"
     CDS             10028..11170
                     /gene="tgt"
                     /locus_tag="VWZ68_001008"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEU9372042.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11268..13085
                     /locus_tag="VWZ68_001009"
     CDS             11268..13085
                     /locus_tag="VWZ68_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU9372043.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTV
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13238..14389
                     /gene="nagA"
                     /locus_tag="VWZ68_001010"
     CDS             13238..14389
                     /gene="nagA"
                     /locus_tag="VWZ68_001010"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEU9372044.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14552..15610
                     /locus_tag="VWZ68_001011"
     CDS             14552..15610
                     /locus_tag="VWZ68_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEU9372045.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15761..16126
                     /locus_tag="VWZ68_001012"
     CDS             15761..16126
                     /locus_tag="VWZ68_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEU9372046.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16202..17143
                     /locus_tag="VWZ68_001013"
     CDS             16202..17143
                     /locus_tag="VWZ68_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEU9372047.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17091..18107
                     /locus_tag="VWZ68_001014"
     CDS             17091..18107
                     /locus_tag="VWZ68_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEU9372048.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18109..18435
                     /gene="comGC"
                     /locus_tag="VWZ68_001015"
     CDS             18109..18435
                     /gene="comGC"
                     /locus_tag="VWZ68_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEU9372049.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQVKAYKEYNDKNGGA
                     NRKVND"
     gene            18404..18832
                     /locus_tag="VWZ68_001016"
     CDS             18404..18832
                     /locus_tag="VWZ68_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEU9372050.1"
                     /translation="MEEQIVKSMIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLPVPKGIQAPSGQSIIF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18837..19097
                     /locus_tag="VWZ68_001017"
     CDS             18837..19097
                     /locus_tag="VWZ68_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372051.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQININGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19060..19521
                     /locus_tag="VWZ68_001018"
     CDS             19060..19521
                     /locus_tag="VWZ68_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU9372052.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALLVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVRFRFQFQKGLEREFIYRVEKEKS"
     gene            19499..19912
                     /locus_tag="VWZ68_001019"
     CDS             19499..19912
                     /locus_tag="VWZ68_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU9372053.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20049..20636
                     /locus_tag="VWZ68_001020"
     CDS             20049..20636
                     /locus_tag="VWZ68_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9372054.1"
                     /translation="MKHDFNHKAETFDSPKNIFLANLVCQAVEKQIDILSDKEILDFG
                     GGTGLLALPLAKQAKSVTLVDISEKMLEQAHLKAEQQAIKNIQFLEQDLPKNPLEKEF
                     DCLAVSRVLHHMPDLDAALSLFHQHLKEDGKLIIADFTKTEANHHGFDLAELENKLIE
                     HGFSSVHSQILYSAEDLFQGNHSEFFLIVAQKSLA"
     gene            20697..21650
                     /locus_tag="VWZ68_001021"
     CDS             20697..21650
                     /locus_tag="VWZ68_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9372055.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVELFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21701..22891
                     /locus_tag="VWZ68_001022"
     CDS             21701..22891
                     /locus_tag="VWZ68_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEU9372056.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGTDAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23040..23411
                     /gene="rnpA"
                     /locus_tag="VWZ68_001023"
     CDS             23040..23411
                     /gene="rnpA"
                     /locus_tag="VWZ68_001023"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEU9372057.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23386..24210
                     /locus_tag="VWZ68_001024"
     CDS             23386..24210
                     /locus_tag="VWZ68_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU9372058.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24229..25215
                     /locus_tag="VWZ68_001025"
     CDS             24229..25215
                     /locus_tag="VWZ68_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEU9372059.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25266..25889
                     /locus_tag="VWZ68_001026"
     CDS             25266..25889
                     /locus_tag="VWZ68_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEU9372060.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLEKQAKILDIPTVKGIYYLAYSDGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26020..27477
                     /locus_tag="VWZ68_001027"
     CDS             26020..27477
                     /locus_tag="VWZ68_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU9372061.1"
                     /translation="MEVISSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFIFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27500..27781
                     /locus_tag="VWZ68_001028"
     CDS             27500..27781
                     /locus_tag="VWZ68_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9372062.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27858..28343
                     /locus_tag="VWZ68_001029"
     CDS             27858..28343
                     /locus_tag="VWZ68_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9372063.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28360..29025
                     /locus_tag="VWZ68_001030"
     CDS             28360..29025
                     /locus_tag="VWZ68_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEU9372064.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            29029..29892
                     /locus_tag="VWZ68_001031"
     CDS             29029..29892
                     /locus_tag="VWZ68_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEU9372065.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29894..30598
                     /locus_tag="VWZ68_001032"
     CDS             29894..30598
                     /locus_tag="VWZ68_001032"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEU9372066.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIIVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30777..32450
                     /locus_tag="VWZ68_001033"
     CDS             30777..32450
                     /locus_tag="VWZ68_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU9372067.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32562..33653
                     /gene="ulaG"
                     /locus_tag="VWZ68_001034"
     CDS             32562..33653
                     /gene="ulaG"
                     /locus_tag="VWZ68_001034"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEU9372068.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33767..35743
                     /gene="tkt"
                     /locus_tag="VWZ68_001035"
     CDS             33767..35743
                     /gene="tkt"
                     /locus_tag="VWZ68_001035"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU9372069.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            35860..36159
                     /gene="yajC"
                     /locus_tag="VWZ68_001036"
     CDS             35860..36159
                     /gene="yajC"
                     /locus_tag="VWZ68_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU9372070.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36206..36634
                     /locus_tag="VWZ68_001037"
     CDS             36206..36634
                     /locus_tag="VWZ68_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEU9372071.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQQYEILYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36636..37046
                     /locus_tag="VWZ68_001038"
     CDS             36636..37046
                     /locus_tag="VWZ68_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372072.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37347..39998
                     /gene="adhE"
                     /locus_tag="VWZ68_001039"
                     /gene_synonym="adhC"
     CDS             37347..39998
                     /gene="adhE"
                     /locus_tag="VWZ68_001039"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEU9372073.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12217 a         7208 c         9079 g        11780 t
ORIGIN      
        1 ccgttaactc ccattttagc gggtgtagtt tagtggtaaa actacagcct tccaagctgt
       61 tgtcgcgagt tcgattctcg tcacccgctt tgaactttgt tctttgtacc aagtttttga
      121 cttgggcgcg tagctcaggt ggttagagcg cacgcctgat aagcgtgagg tcggtggttc
      181 gagtccactc gtgcccatag tgtttagtcc attactaggg gattggaata ttatctgttc
      241 actaagagga cacgggcttg ttcccgtata aactattttg gaggattacc caagtccggc
      301 tgaagggaac ggtcttgaaa accgtcaggc gtgtaaaagc gtgcgtgggt tcgaatccca
      361 catcctcctt ttatattaac gcgggatgga gcagctcggt agctcgtcgg gctcataacc
      421 cgaaggtcgt aggttcaaat cctgctcccg caataaggct cggtagctca gttggtagag
      481 caatggattg aagctccatg tgtcggcggt tcgattccgt ctcgcgccat ttatatattt
      541 tggaagggta gcgaagaggc taaacgcggc ggactgtaaa tccgctcctt cgggttcggg
      601 ggttcgaatc cctccccttc cattttacgg gcatagttta aaggtagaac taaggtctcc
      661 aaaaccttca gtgtgggttc aattcctact gcccgtgtta atagaattat ggcgggtgtg
      721 gtgaagtggt taacacacca gattgtggct ctggcatgcg tgggttcgat ccccatcact
      781 cgcctatttt atattggggt atagccaagc ggtaaggcaa gggactttga ctccctcatg
      841 cgttggttcg aatccagcta ccccagttac tatttgccgg cgtggcggaa ttggcagacg
      901 cgctggactc aaaatccagt gtccgcaagg acgtgccggt tcgaccccgg ccgccggtat
      961 agtatagtgt taggaacgtt gttattcttc gttccttttt tatattattt ttggtataat
     1021 tatagttatt caaattttgt ttagattgag aaagtgtagg gtagtatgtc ttgttctatc
     1081 gatttattaa aacatcggta tttgaaaaat attaaagaaa atcctgaatt gtttgtcgga
     1141 attgagttgg agtatcctgt tgcaagttta gaaggggatg ctacagatgt tgaagttata
     1201 aaggatctat ttcattattt agtttctact ttggatctca ccgtagcaaa ggtagatgat
     1261 tttggcaatc tgatccagtt agtagatccg ataagtcagg atgctatttt atttgaagtt
     1321 tcctatacaa cgattgagtt tgcatttggt aaggctgaaa cgattcaaga ggtcgaaaat
     1381 cgtttcaata attatatgaa tgtaattcag agaaagttag ctgaatcaaa tcatgctatt
     1441 gttggctgtg gtatccatcc caactgggat aaaaatgaga attgtccagt ggcttatcca
     1501 cgctatcaga tgttgatgga ttatttgaat ttgagtagaa atattattaa atcagattta
     1561 catcatttcc ctgaatatgg tacttttatc tgtgggagcc aggttcagct ggatatttca
     1621 aaaaccaact acttacgggt gattaatgct tttactcaaa ttgaagcggc taaggcttat
     1681 ttatttgcaa actctgaatt ttcgggtgcg gattgggata cgaaaatttc aagggatatt
     1741 ttctgggaag aatctatgca tggtatctat ccagagaatg ttggggtcaa tgctagactc
     1801 cttaatgatg aagctgattt ttttgactat ctaaatcatt ctgcgatttt tactgcggaa
     1861 cgtgatgggc agacctatta tttttatcct attcaggctg gggactattt ggctacgcct
     1921 gaaatccaag catttgctct gaatggggat gaggttatta tttcccccca agagaaggat
     1981 tttgaaactc atcgtagtta ccagtaccaa gacttaacga ctcgaggaac agttgagttt
     2041 cgtagtgtgt gtacacagcc acttgatagg acttttgctt ctgcagcttt tcacttggga
     2101 ttattggtta atttagacaa gttagaagct tacttagaaa cagcaccttt ctttaaagta
     2161 tttggttatg attacaagtc tttaaggaga caattttcta agaaaaatct tacagatgag
     2221 gaagaaacta cgattattga attttccaaa gacttactcc tactagctga ggagggacta
     2281 gtggtgagaa ataaggaaga aatgacctat ttacagcctt tgagagaaga attgagccta
     2341 taatttctct tataaaggga gaattttctg aaaaatcatg atataatgga cgagactata
     2401 gataaaggat agagagtaat gacattagtt tatcaatcaa cgcgtgatgc caacaataca
     2461 gtaactgcca gccaagcaat tttgcaaggt ttggcgacgg acggcggttt gtttacaccg
     2521 gttacttatc caaaggtaga tttggacttt gacaaattga aagatgcttc ttaccaggaa
     2581 gttgctaagc tagttttgtc agcattttta gatgacttta cagctgagga gttggactac
     2641 tgtatcaaca atgcctacga tagcaaattt gatactccag ctattgcact attagtgaaa
     2701 ttagatgggc aatacaattt ggaacttttc catggttcaa cgattgcctt taaggatatg
     2761 gccttgtcta ttttgccata ctttatgacg actgctgcta agaaacatgg tttggagaac
     2821 aagattgtta tattgacagc gacatctggt gacacgggga aagctgctat ggcggggttt
     2881 gcggatgtgc ctggtactga gattatcgtc ttttatccaa aggatggtgt cagcaagatt
     2941 caagagttac aaatgaccac tcagactggc gacaatactc atgttattgc tattgatggt
     3001 aactttgacg atgcgcaaac aaatgtgaag cacatgttta acgatgtggc tcttcgtgaa
     3061 aaattgacta ccaacaagtt gcaattttca tcagctaact ctatgaacat tggtcgtctg
     3121 gtgccacaaa ttgtttatta tgtttatgct tacgctcaat tggttaagac tggtgaaatt
     3181 gtagctggtg aaaaggttaa cttcacagta ccaacaggaa actttggaaa tatcttggct
     3241 gccttttatg ccaaacaaat tggtttgcca gttggtaaat tgatctgtgc ttcaaatgac
     3301 aacaatgttt tgacagactt ctttaaaaca cgtgtctatg acaaaaaacg tgagtttaag
     3361 gtaacaacca gcccatctat ggatatcttg gtatcttcaa acttggagcg cttgattttc
     3421 catcttttgg gaaataatgc tgaaaagaca gctgaactca tgaatgcttt gaacatgcaa
     3481 ggacaatata agttgacaga ctttgatgca gagattctgg agctctttgc agctgaatat
     3541 gcgactgagg aagaaacagc ggcagaaatc aagcgtgttt atgagttaga ttcttatatt
     3601 gaggatccac atacggcggt tgcctcagca gtttatagaa aataccaagc ggttactgat
     3661 gatgcgacta agacagtgat tgcttcaaca gctagtccct acaagttccc agtagttgca
     3721 gtagaagctg taactggaaa agcaggttta acagactttg aagccttggc tcaattacat
     3781 gaaatctcag gcgttgcagt gccaccagca gttgatgggc ttgagacagc tcctgttcgt
     3841 cacaagacaa ctgtagcggc tgctgatatg caagcagcgg ttgaggctta tttaggactt
     3901 taagatagag ggagtaaact cggttgggaa accaactgag tttcttttca tcaggaggag
     3961 agattgttta agaaaaataa agacattctt aatattgcat tgccagctat gggtgaaaac
     4021 tttttgcaga tgctaatggg aatggtggac agttatttgg ttgctcattt aggattgata
     4081 gctatttcag gggtttcagt agctggtaat attatcacca tttatcaggc gattttcatc
     4141 gctctgggag ctgctatttc cagtgttatt tcaaaaagca tagggcagaa agaccagtcg
     4201 aagttggcct atcatgtgac tgaggcgttg aagattacct tactattaag tttcctttta
     4261 ggatttttgt ccatcttcgc tgggaaagag atgataggac ttttggggac ggagagggat
     4321 gtagctgaga gtggtggact gtatctatct ttggtaggcg gatcgattgt tctcttaggt
     4381 ttaatgacta gtctgggagc cttgattcgt gcaacgcata atccacgtct gcctctctat
     4441 gttagttttt tatccaatgc cttgaatatt cttttttcaa gtctagctat ttttgttctg
     4501 gatatgggga tagctggtgt tgcttggggg acaattctgt ctcgtttggt tggtcttgtg
     4561 attttgtggt cacaattaaa actgccttat gggaagccaa cttttggttt agataaggaa
     4621 ctgttgacct tggctttacc agcagctgga gagcgactta tgatgagggc tggagatgta
     4681 gtgatcattg ccttggtcgt ttcttttggg acggaggcag ttgctgggaa tgcaatcgga
     4741 gaagtcttga cccagtttaa ctatatgcct gcctttggcg tcgctacggc aacggtcatg
     4801 ctgttggccc gagcagttgg agaggatgat tggaaaagag ttgctagttt gagtaaacaa
     4861 accttttggc tttctctgtt cctcatgttg cccctgtcct ttagtatata tgtcttgggt
     4921 gtaccattaa ctcatctcta tacgactgat tctctagcgg tggaggctag tgttctagtg
     4981 acactgtttt cactacttgg gacccctatg acgacaggaa cagtcatcta tacggcagtc
     5041 tggcagggat taggaaatgc acgcctccct ttttatgcga caagtatagg catgtggtgt
     5101 atccgcattg ggacaggata tctgatgggg attgtgcttg gttggggctt gcctggtatt
     5161 tgggcagggt ctctcttgga taatggtttt cgctggttat ttctacgcta tcgttaccag
     5221 cgctatatga gcttgaaagg ataggaaatg caaaaaacag cttttatttg ggatttagac
     5281 gggactttat tggactctta cgaagcgatt ttatcaggga ttgaggagac ttttgctcag
     5341 ttttctattc cttatgataa ggagaaggtg agagagttta tcttcaagta ttcggtgcaa
     5401 aatttgcttg tgcgggtggc agaagataga aatctggatg ttgaggtgct aaatcaggtg
     5461 cgtgcccaga gtctggctga gaaaaatgct caggtagttt tgatgccagg tgcgcgtgag
     5521 gtgctagctt gggcagacga atcaggaatt cagcagttta tatatactca taaggggaac
     5581 aacgctttta ccattctcaa ggacttgggg gtggaatcct attttacaga gattttaacc
     5641 agtcagagtg gctttgtgcg gaagccaagt ccagaagcgg ctacctatct gctagataag
     5701 tatcagttga attctgataa tacttattat ataggggatc ggactctgga tgtggaattt
     5761 gcccagaata gtgggattca aagtatcaac tttttagagt ctacttatga agggaatcac
     5821 aggattcaag cgttagcaga tatttcccgt atttttgaga ctaagtgata aaaagattgt
     5881 gtcagttttg tgacagagac ctaacaaact atttcaagta acctagtttg ttacaaggaa
     5941 tagacagttc tgttaaatag gcccgagagg gctttttttc tacatttttt gtgttatgat
     6001 agacaggtac taatttgaaa ggaatttgaa agaatgaaga aaagaatgtt attagcgtca
     6061 acagtagcct tgtcatttgc cccagtattg gcaactcaag cagaagaagt tctttggact
     6121 gcacgtagtg ttgagcaaat ccaaaacgat ttgactaaaa cggacaacaa aacaagttat
     6181 accgtacagt atggtgatac cttgagcact attgcagaag ccttgggtgt agatgtcaca
     6241 gtgcttgcga atctgaacaa aatcactaat atggacttga ttttcccaga aactgttttg
     6301 acaacgactg tcaatgaagc agaagaagta acagaagttg aaatccaaac acctcaagca
     6361 gactctagtg aagaagtgac aactgcgaca gcagatttga ccactaatca agtgaccgtt
     6421 gatgatcaaa ctgttcaggt tgcagacctt tctcaaccaa ttgcagaagc tccaaaagaa
     6481 gtagcatcaa gttcagaagt tacaaagaca gtgattgctt ctgaagaagt ggcaccatct
     6541 acgggcactt ctgtcccaga ggagcaaacg gccgaaacaa gcagtgcagt tgcagaagaa
     6601 gctcctcagg aaacgactcc aggtgagaag caggaaacac aagcaagccc tcaagcagca
     6661 tcagcagtgg aagcaactac aacaagttca gaagcaaaag aagtagcatc atcaaatgga
     6721 gctacagcag cagtttctac ttatcaacca gaagagacga aaataatttc aacaacttac
     6781 gaggctccag ctgcgcccga ttatgctgga cttgcagtag caaaatctga aaatgcaggt
     6841 cttcaaccac aaacagctgc ctttaaagaa gaaattgcta acttgtttgg cattacatcc
     6901 tttagtggtt atcgtccagg agacagtgga gatcacggaa aaggtttggc tatcgatttt
     6961 atggtaccag aaagttcaga attaggggat aagattgcgg aatatgctat tcaaaacatg
     7021 gccagccgtg gcattagtta catcatctgg aaacaacgtt tctatgctcc attcgatagc
     7081 aaatatgggc cagctaacac ttggaatcca atgccagacc gtggtagtgt gacagaaaat
     7141 cactatgacc acgttcacgt ttcaatgaat ggataaaccc gacttggtaa catcattttg
     7201 acgaatgaga tctagctttc gtgataggaa gcgattctcg ttcgtttttt ctttgtcata
     7261 ctcttcgaaa atctcttcaa accacgtcag ttttatctga aacctcaaag ctgtgctttg
     7321 agcaacctgc gactagcttt ctagtttact ctttgatttt cattgagtat caatttgaat
     7381 ggaaaatgga aagttattat cttgtaataa tccaagcaac attcttgcaa tctattttac
     7441 tttatatcac aattgattgg tcaactattg ataagtcaat ggataggagg aagaaatgat
     7501 agagattcaa gatttactgt atcaactccg cttgtctgag caagcgagta cgcaattgtt
     7561 tgaaaaaggc ttgggattag tttgacacgg tatcagattt tactgttttt gctggagcat
     7621 tctccttgta accaaatggc ggttcaggag cgtttgaaaa ttgatcaggc tgctttgaca
     7681 cggcatttca agattttgga aacggaaggt ttggtggagc gtcatcgtaa tcctgaaaat
     7741 cagcgggaag tgttggtaga ggctgcgaag tatgccaagg agcagttagt ggtgaatccc
     7801 cctctgcaac atatcaaggt taaggaagag atggaaagta tcttaacaga gtttgagaga
     7861 acagaactca gccgtttatt aaataaattg gttttgggta ttgaaaatat agaaatttaa
     7921 ggagaaatag atgtcaatta ttttaacaac gatcgttgct ttggagcatt tttacatttt
     7981 ttatttggaa agtattgcca cgcaatcaga tgcgactagt cgtgtattta atatggaaaa
     8041 ggaagaattg gctcatccgt cagtaagttc attgttcaaa aatcaaggaa tttataaggc
     8101 tctgctagga gtctttctct tgtatgtcat ttatttctca cagaatttag aaattgtgac
     8161 tatttttgtc ttatttgtga ttggtgctgc gacttacggc tctttaacag cggataaaaa
     8221 attattttga agcaaggtgg atcagctatt ttggccttga ttagtatttt actctttaaa
     8281 tacacttgaa ggttgattct aatctcgcta atccttttta atccagaata agggaaatat
     8341 gttatacttg tttttaagaa aaaagtctca ttgaattggt tttgaggagt tagaaatgaa
     8401 agtattagtg acaggttttg agcccttttg aggccattaa aggtttacca gctgaaatcc
     8461 atggtgctga ggtccgttag ctagaggtgc cgacagtttt tcacaaatct gctcaagtat
     8521 tggaagaaga gatgaatcgt tatcaacctg actttgtcct ttgtattggg caagctggtg
     8581 gaagaactag tttgacacct gaacgagtgg ccattaatca agacgatgca cgcatttctg
     8641 ataacgaaga taatcaaccg attgaccgtc ccattcgccc agatggtgct tcggcctact
     8701 ttagtagttt gccgattaaa gcgatggttc aagctataaa aaagagggct taccggcctc
     8761 tgtttccaat acggcaggga cttttgtctg cagccatttg atgtatcagg ctctctattt
     8821 ggtagaaaag aaatttccat atgttaaggc aggttttatg catattcctt atatgatgga
     8881 acaggtggtg aacagacaga ctattccagc tatgagttta gtggatattc ggagagggat
     8941 agaagcagca atcggcgcta tgatagaaca tggagatcag gaactcaagt tggtaggcgg
     9001 agaaactcat tgatagaaaa aagcttgagt ggaaaaacct tcaagctttt ggacgttttc
     9061 gagccaatac tgctcggtaa aacataattt tagtgcattg gatataaggt aggagtgaaa
     9121 aactagcaat gccaaaggta atccaattga ggaagtacca aggaagaagc tgtaaatcta
     9181 ggacaaagcg ctggaacttg tagcccttca taaaggaacg gctagttttt aggattcgtc
     9241 ttggtgggac ctgtcctagg tctagactat aacagagaag aaattccacc tgtgaatagg
     9301 cataatactg tggaatatag aggatatttc ctacaatgat caagatgaga cttgcaagaa
     9361 agtagagtcc aaagaccatg aggaaacgct cggtttcaac tgatgagaga tctagatttg
     9421 gaaactcagg atgtagggtg acgaattttt tggctaaaaa gctactataa aagaggaggt
     9481 aaatcccaag taaattaggg atactccata aaaagagata gaaacgtttg agaagtaggg
     9541 tcaaaaaggt ttgagaaaag cgctcctcat caaagagagc taggctgttt tttacagatg
     9601 gctccgtttt agaatctttc atgagtgtca gtgttgcata gacggaactg gtcaaaagaa
     9661 tagtcccgat aaagaagact agtagaggaa agaggtaggc ttgaagtatt tggccaagta
     9721 tgctgaaaaa tggctgttct aaaacagtcc cgtggatccg agataaggga ttaagaaaac
     9781 tagataagat gaccagcata ctgggaagga tatagaggag aaagagacgg ggggtgtcag
     9841 cctgaaaatg ttttgactcc tgacgaattg tttttaaatc aatttttgga tagttcattc
     9901 tcttattata ccatagttct tatacatagt tcgtgacagt tcctactttt tttgataaaa
     9961 tcatacagtg tgtccttggg cacactgtat gaactgggac tgtctttccc agcttcggag
    10021 gtaaaaaatg tcagattcac caatcaaata tcgtttgatt aagaaagaaa aacacacagg
    10081 agctcgtctg ggagaaatca tcactcccca cggtaccttt ccgacaccta tgtttatgcc
    10141 agttgggaca caagccactg tcaaaactca gtcacctgaa gaattgaagg agatgggttc
    10201 gggaattatc ctatcaaaca cctatcatct ctggcttcgc cctggagatg aactcattgc
    10261 acgcgctggt ggtctccaca agttcatgaa ttgggaccag cctatcttga cagatagtgg
    10321 tggttttcag gtttattctt tagcagatag ccgtaatatc acagaagaag gagtaacctt
    10381 taaaaatcat ctaaatggtt ctaagatgtt cctatcccca gaaaaagcca tctctattca
    10441 gaataatctg ggttcagaca tcatgatgtc ctttgatgaa tgtcctcagt tttatcaacc
    10501 ttatgactac gttaagaaat cgatcgagcg taccagccgt tgggctgagc gtggtttgaa
    10561 ggctcaccgt cgtccacatg accaaggttt gtttggaatt gtgcaaggtg caggatttga
    10621 agaccttcgc cgccaatcag ctcatgatct tgtcagcatg gatttctcag gctactctat
    10681 cggtggtttg gcagtgggag aaacccatga agagatgaat gcggtcttgg actttacaac
    10741 tcaactgcta cctgaaaata aacctcgtta tctgatgggt gtgggagcgc cagatagctt
    10801 gatcgatggg gtcattcgtg gggtggatat gtttgactgt gtcttaccga ctcgaattgc
    10861 tcgtaacggg acttgtatga ccagtcaagg acgtttggtt gtgaaaaatg cccagtttgc
    10921 tgaggacttt acgccactgg atcctgagtg tgactgctac acatgtaata actatacacg
    10981 cgcttacctt cgtcacctgc tcaaggctga tgaaaccttt ggtatccgct tgactagcta
    11041 ccacaatctt tacttcttgc ttaacctgat gaagcaagtg cgacaagcca tcatggatga
    11101 caatctcttg gaattccgtg agtattttgt ggaaaaatat ggctataata agtcaggacg
    11161 taatttctaa aatggaattg atataaaaaa atcctaagtt ttctcttagg atttttcttc
    11221 tttttttgat agaataaagt gtacaatgaa aggaagaata aactcgtatg cgcattaaat
    11281 ggttttcctt gattaggatt ataggtttac ttttggtact cttgtatcac ttctttcaga
    11341 cgatctttcc tggaggattc ttcggggtag atgtcttttt cacattttca ggtttcctga
    11401 ttacagctct actcattgaa gaattttcta agaacaatga gattgatttg ataggatttt
    11461 ttagaagacg cttttatcgg attgtgccac ctgtggtttt gatggtcttg gtgaccatgc
    11521 cttttacttt cttggttcgc caagactatg ttgctggaat tggtggccag attgcgggcg
    11581 tcttaggctt tatgaccaac ttctatgaac tcctaacagg tgggagttat gaatctcagt
    11641 tcattcctca tttgtttgtt cataattgga gtttggcagt tgaggttcac tactatattc
    11701 tttggggatt ggcagtttgg ttcttatcca aacaagctaa atcaaatggt cagttgaagg
    11761 ggatggtctt tctcttatct gctgctgcct tcttgatcag tttcttctcc atgtttattg
    11821 gtagttttct agtgacctct tattcctctg tttatttctc cagtttaact catgtctatc
    11881 cattcttttt gggaagtatg ttagcaacta ttgtaggcgt tcgtcagacg acttccctcg
    11941 tcaagcagtt ggataaaatc tgggatttac gaaagacttt ggtagttttt ggaggaggct
    12001 ttggtttcct agttcttttg actttctttg tcaaattcac ttatcttttt gcctatctta
    12061 tcggcttctt gcttgccagt cttgcagctc ttgccatgat tctggcggcg cgtgtcttac
    12121 atgaaaagac acatcatata caggagccga agattatcag ctttttagcg gatactagct
    12181 atgcggttta tcttttccat tggcctttct atatcatttt ctcacagttg acatcaaatc
    12241 ttcttgctgt attactgact ctgatttgtt cttatggctt tgccagtctg tcattctatg
    12301 tattggaacc ttggattgca ggcaagaaca cacctatttt acaaactctt cgtcccctgc
    12361 cttatattca cgcaattctt gcagcaggta caggaatctt gaccttcatt gtctgcatgg
    12421 tgaccttgtt ggcaccacaa gtgggagcgt ttgagacaga cttgactgtc aatggcttga
    12481 agcaagctgc aacaaatatt ggccagacca aggtgatggc agaacgggca gatgcaaaca
    12541 gtttgggaat tgctgatggc actatgttaa ttggtgactc agtggcttta agggcaaata
    12601 cagcactaca gacagttctt cctggagcac agattaacgc gcaggtcagc gtaacaacca
    12661 agaccgcaaa tgaaatcatg ctaaataata gccagaataa atttttacct aagacggtgg
    12721 tcattgcgac tggggtaaat aatcctgaga attacaagga tgactgggac agtatcgtga
    12781 aaaatcttcc taagggacac catatgattt tggtgactcc ttatgaggga gataagacaa
    12841 aagagaccta tgccatcgtt gagaaggctg ctgcctatat gagagaattg gcagagaaga
    12901 caccttacat tacgatagca gattggaatc aagttgcgaa agagcatcca gaaatttggg
    12961 caggaacaga ccaggttcat ttcgggagtg agagtagcac tatcgaagca ggagcaaaat
    13021 tgtatgcaga tacgattgcc acagctttgc agacagctca agacaagccg gttaaatcaa
    13081 aataacttgt attaaaaaag agaagagttg gagaaatcca gctcttttaa aatatctcca
    13141 aaaaataggt ctataccatt tacaaataaa aaagaaaggt ttataatgta attgacataa
    13201 taaattgtag aatcaatctt ttaaggaggt taacattatg cctaactata ttaaagcgga
    13261 tcagtttttc tacccacacg gagttcgtcg aggtggttac ttggaacttg tggacggcaa
    13321 gtttgggaaa catgtagagc agattcctga aggggctgag gtgattgact atacaggtta
    13381 tagcattgcc ccaggtcttg tggatactca tattcatgga tatgcaggtg tagatgtgat
    13441 ggacaacaac attgaaggta cattgcatac tatgagtgaa ggacttctta gtaccggtgt
    13501 taccagtttc ttacccacaa ctttaacagc cacttatgag caattgcttg cagtcactga
    13561 aaatcttgga aaccattata aagaagcaac aggtgctaag attcgtggga tttattatga
    13621 aggtccatat ttcacagaaa cttttaaggg ggcacaaaat ccaacttata tgagagaccc
    13681 gggtgttgag gagtttcatt cttggcaaaa agcggcaaat ggcttgctta ataaaattgc
    13741 ccttgcacca gaacgtgatg gggtggaaga ctttgttcgt acagttacgg gcgaaggtgt
    13801 gacggttgct cttggacatt caaacgcgac ttttgatgaa gccaaaaaag cagtcgatgc
    13861 tggagcgagt gtttgggtgc atgcctacaa tggaatgcgt gggttgactc accgtgaatt
    13921 gggtatggtt ggagccatgt accaattgcc acatacctat gcagagttga tctgtgatgg
    13981 tcaccacgta gatccaaagg cttgcgaaat tcttatcaaa caaaaaggaa cagaaaacat
    14041 cgctcttatc acagactgta tgacagctgg gggattggaa gacggagatt atatgttggg
    14101 agaattccca gttgtcgttg caaatggaac tgcacgcctc aaatcgacag gtaacttggc
    14161 aggttctatc ctcaaactca aagatggttt gaagaatgtg gtcgaatggg gaattgcgaa
    14221 tccgcatgaa gcagtcatga tggccagctt caacccagct aaatccgttc acatcgatga
    14281 cgtctgtggc caaatccgtg aaggctacga cgctgacttc atcgtattag ataaagattt
    14341 ggaattggta gcaacctacc tagatggcgt gaaacgttat caagcataag agagaaagca
    14401 gaagttagag actaacttct gcttttttat gcagggtact ttactggtaa ataaaaagtt
    14461 aaaaaaatca caaaaaaagc ttgaagaaac aaagaaaaag gcttacaatt gaactataaa
    14521 tattacaaat aaaaaaacgg aggagtgctt tatgaaagct tatacttatg ttaaaccagg
    14581 acttgcttct tttgttgatg tagacaaacc agttattcgc aagccaacag acgctattgt
    14641 gcgtattgta aaaaccacta tttgtggaac agacctccat attatcaaag gggatgttcc
    14701 tacttgccaa agtggtacca ttcttggcca cgaagggatt gggattgttg aagaagttgg
    14761 ggaaggagtt tccaacttca aaaaaggtga caaggtcttg atttcttgcg tctgtgcctg
    14821 tggtaaatgc tactactgta aaaaaggaat ttatgcccac tgtgaagacg aagggggctg
    14881 gattttcggt cacttgattg atggtatgca ggctgaatat ctacgtgtcc ctcatgcaga
    14941 taatactctt taccatactc cagaagactt gtcagatgaa gctttggtta tgctgtcaga
    15001 cattctgcct actggatatg aaattggtgt cttaaaaggg aaagtagaac ctggttgcag
    15061 cgtagccatt attggttcag gtccagttgg attggctgct cttttaacag cccaattcta
    15121 ttcaccagct aaattgatta tggtagacct agacgataac cgtttggaaa ctgccctatc
    15181 attcggtgcg actcataagg taaactcttc agaccctgaa aaagcgataa aagaaattta
    15241 tgatttgaca gatggtcgcg gtgtagatgt cgctattgaa gctgtaggga ttcctgaaac
    15301 atttgatttc tgtcaaaaga ttatcggtgt agacggaacg gttgccaact gtggtgtgca
    15361 tggtaaacca gttgaattcg atttagataa actttggatt cgtaacatca atgtaacaac
    15421 tggtttggta tctacaaata cgactccaca attgttgaaa gcacttgaaa gtcataagat
    15481 tgaaccggaa aaattggtaa ctcactattt caaactcagt gaaattgaaa aagcctacga
    15541 agtcttcagt aaggcagcag accaccatgc cattaaggtc attatcgaaa acgatatctc
    15601 agaagcctaa gtagtaaaaa tatttttgta cataagcaaa tagaaattca gtcatccatc
    15661 agatggctgg attttttatc aaaaaattaa gaaatgagca tatttctttc cttgtctggc
    15721 ggaattggtt ataatatacg gtacaaagga atgaatgaat atgtatcgtg ttatagaaat
    15781 gtacggagat tttgaaccgt ggtggttctt agaaggttgg gaagaagata ttgtagcaag
    15841 tagaaaattt gaccagtatt atgatgctct caaatactac aaaacttgct ggtttagatt
    15901 agaacaagaa tcccctcttt ataaaagtag aagcgacttg atgaccattt tttgggaccc
    15961 ggaagaccaa cgctggtgtg atgaatgtga tgagtattta caacaatacc attctttggc
    16021 tcttttgcag gatgagcagg ttatcccaga cgaaaaacta cgctcaggct atgaaaaaca
    16081 aaccagtcag gaaaggaatc gttcttgccg tatgaaatta aaatagagaa aagtaacttt
    16141 tttggagttg ctttttttat ttttctaacg ctttgcgaat agtataggtg aggaggtaag
    16201 tatggttcaa gaaattgcac aagaaatcat tcgttcggct cggaaaaaag gggcgcaaga
    16261 catttatttt gtccctaagt tagatgccta tgagcttcat atgagggtag gagacgagcg
    16321 ctgtaaaatt ggtagctatg attttgaaaa gtttgcagcc gttatcagtc actttaagtt
    16381 tgtggcgggt atgaatgtgg gagaaaaaag acgtagtcaa ctgggttcct gtgattatgc
    16441 ctatgaccag aagatggcgt ctctacgttt atctactgta ggcgattatc gggggcatga
    16501 gagtttggtt atccgtttgt tgcacgatga ggagcaggac ttgcattttt ggtttcagga
    16561 tattgaagaa ttaggcaagc agtacaggca acggggactc tatctttttg ctggtccggt
    16621 tgggagtggt aagacgacct tgatgcatga attgtccaag tcactcttta aaggacagca
    16681 agttatgtcc atcgaagatc ctgtcgaaat caagcaggac gacatgcttc agttgcagtt
    16741 gaacgaagca atcggcctaa cctatgaaaa tctaatcaaa ctttccttgc gtcatcgacc
    16801 agatctcttg attatcggag aaattcgtga cagcgagacg gcgcgtgcag tggtcagagc
    16861 tagtttgaca ggtgcgacag tcttttcaac cattcacgcc aaaagtatcc gaggtgttta
    16921 tgagcgtctg ctggagttgg gtgtgagtga agaagaattg gcagttgttc tgcaaggagt
    16981 ctgctaccag agattaatcg ggggaggagg aatcgttgac tttgcaagca gagattatca
    17041 agaacaccaa gcagccaagt ggaatgagca aattgaccag cttcttaaag atggacatat
    17101 cacaagtctt caggctgaga cggaaaaaat tagctacagc taagcaaaaa aatatcatca
    17161 ccctatttaa caatctcttt tctagcggtt ttcatctggt ggagaccatc tcctttttag
    17221 ataggagtgc tttgttggac aagcagtgtg tgacccagat gcgtgtgggc ttgtctcagg
    17281 ggaaatcatt ctcagaaatg atggaaagtt tgggatgttc aagtaccatt gtcactcagt
    17341 tatctctagc tgaagttcat ggcaatcttc acctgagttt gggaaagata gaagaatatc
    17401 tagacaatct ggccaaggtc aagaaaaagt taattgaagt agcgacctat cctttgattt
    17461 tgctgggttt tcttctctta attatgctgg ggctacggaa ttacctgctc ccacaactgg
    17521 atagtagcaa tattgccacc cgaattatcg gtaatctgcc acaaattttt ctaggcatgg
    17581 tagggcttgt ttccgtgctt gcccttttag cactaacttt ttataaaaga agttctaaga
    17641 tgagtgtctt ttctatctta gcacgccttc cctttattgg aatctttgtg cagacctact
    17701 tgacagccta ttatgcacgt gaatggggga atatgatttc acagggaatg gagctgacgc
    17761 agatttttca aatgatgcag gaacaaggtt cccagctctt taaagaaatc ggtcaagatc
    17821 tggctcaaac cctgaaaaat ggccgtgaat tttctcagac gataggaacc tatcctttct
    17881 ttaggaagga attgagtctc atcatagagt atggggaagt taagtccaag ctgggtagtg
    17941 agttggaaat ctatgctgaa aaaacttggg aagccttttt tacccgagtc aaccgcacca
    18001 tgaatttggt gcagccactg gtttttatct ttgtggcact gattatcgtt ttactttatg
    18061 cggcaatgct catgcccatg tatcaaaata tggaggtaaa tttttaaaat gaaaaaaatg
    18121 atgacattct tgaaaaaagc taaggttaaa gcttttacat tggtggagat gttggtggtc
    18181 ttgctgatta tcagcgtgct tttcttgctc tttgtaccta atctgaccaa gcaaaaagaa
    18241 gcagtcaatg acaaaggaaa agcagctgtt gttaaggtgg tggaaagcca ggcagaactt
    18301 tatagcttgg aaaagaatga agatgctagc ctaagcaagt taaaagacga tgggcgaatc
    18361 acggaagaac aggttaaagc ttataaagaa tacaatgata aaaatggagg agcaaatcgt
    18421 aaagtcaatg attaaggcct ttaccatgct ggaaagtctc ttggttttgg gtcttgtgag
    18481 tatccttgcc ttgggcttgt ccggctctgt tcagtccact tttgcggcag tagaggaaca
    18541 gattttcttt atggaatttg aagaactcta tcgggaaacc caaaaacgca gtgtagccag
    18601 tcagcaaaag actagtctga acttagatgg gcagatgatt agcaatggca gtcaaaagtt
    18661 gccagtccct aaaggaattc aggccccatc aggccaaagt attatatttg accgtgctgg
    18721 gggcaattcg tccctggcta aggttgaatt tcagaccagt aaaggagcga ttcgctatca
    18781 attatatcta ggaaatggaa aaattaaacg cattaaggaa acaaaaaatt agggcagtga
    18841 ttttactgga agcagtagtc gctctagcta tctttgccag cattgcgacc ctccttttgg
    18901 gacaaattca aaaaaatagg caagaggaag caaaaatctt gcaaaaggaa gaagtcttga
    18961 gggtagctaa gatggccttg cagacggggc aaaatcagat aaacatcaac ggagttgaga
    19021 ttcaggtatt ttctagtgaa aaaggattgg aggtctacca tggttcagaa cagttgttgg
    19081 caatcaaaga gccataaggt caaggctttt accttgttag aatccctgct tgccctgctt
    19141 gtcatcagtg ggggcttact cctttttcaa gctatgagtc agctcctcat ttcagaagtt
    19201 cgctaccagc aacaaagcga gcaaaaggag tggctcttgt ttgtggacca acttgaggca
    19261 gaattagacc gttcgcagtt cgaaaaagta gaaggcaatc gcctatacat gaagcaagat
    19321 ggcaaggaca tcgccatcgg taagtcaaag tcagacgatt ttcgtaaaac cgatgctagt
    19381 ggacgaggtt atcagcctat ggtttatggg ctcaaatccg cacagattac agaggacaat
    19441 caactggtgc gctttcgttt ccagtttcaa aaaggcttag aaagggagtt catctatcgt
    19501 gtggaaaaag aaaaaagtta aggcaggtgt tctcctctac gcagtcacca tagcagccat
    19561 ctttagtctt ttgttgcaat tttatttgaa ccgacaaatc gcccactatc aagactatgc
    19621 tttaaataaa gaaaaattgg ttgcttttgc catggctaaa cgaaccaagg ataaagccga
    19681 gcaagaaagt ggggaacagg tctttaatct aggtcaggta agctatcaaa acaagaaaac
    19741 aagcttggtg acgactgttc gtacgtctaa gagccaatat gagtttctgt ttccttcagt
    19801 caaaatcaaa gaagagaaaa gagataaaaa ggaagaggta gcgaccgatt caagcgaaaa
    19861 agtggagaag aaaaaatcag aagagaagcc tgaaaagaaa gagaattcct agtcaattca
    19921 actataatgc gttgaatcca gaatagttca ctgtagtttc tagaaaattg ctggaaatgg
    19981 atgttaagct ccaatttatt tgtttatatc ttatttcagt ttactatact ttgtgctaaa
    20041 ctaaagatat gaaacatgat tttaaccaca aagcagaaac tttcgattcc cctaaaaata
    20101 tcttcctcgc aaacttggta tgtcaagcag tcgagaaaca gattgatatt ttatcagaca
    20161 aagaaatttt agatttcggt ggtggcacgg gtctattagc cttgccccta gccaagcagg
    20221 ctaagtcagt tactcttgta gacatttctg agaaaatgtt ggagcaagct catttgaaag
    20281 cggagcagca agcaatcaag aatatccagt ttttggagca agatttaccg aaaaatccct
    20341 tggagaaaga gtttgattgc cttgctgtta gtcgggttct tcatcatatg cctgatttgg
    20401 atgcggctct ctcactgttt catcaacatt tgaaggaaga tgggaaactc atcattgctg
    20461 attttaccaa gacagaagct aatcatcatg gatttgattt agctgaactg gaaaacaagc
    20521 taattgagca tggtttttca tctgtgcata gtcagattct ctatagcgct gaagacttgt
    20581 ttcaaggaaa tcactcagaa ttctttttaa tagtagccca aaaatcactc gcctagtcag
    20641 ggagtgattt ttctataagg atggaaaaaa gaagggaaat ttgataagat aggaatatgg
    20701 attttgaaaa aattgaacaa gcttatacct atttactaga gaatgtccaa gtcatccaaa
    20761 gtgatttggc gaccaacttt tatgacgcct tggtggagca aaacagcatc tatctggatg
    20821 gtgaaactga gctaaaccag gtcaaagaca acaatcaggc ccttaagcgt ttagcactac
    20881 gcaaagaaga atggctcaag acctaccagt ttctcttgat gaaggctggg caaacagaac
    20941 ccttgcaggc caatcaccag tttacaccgg atgctattgc tttgcttttg gtgtttattg
    21001 tggaagagtt gtttaaagag gaggaaatta ctatcctcga aatgggttct gggatgggaa
    21061 ttctaggcgc tactttcttg acctcgcttg ataaaaaggt ggattacttg ggaatggaag
    21121 tggatgattt actgattgat ctggcagcta gcatggcaga tgtaattggt ttgcaggctg
    21181 gctttgtcca aggagatgcc gttcgtccac aaatgctcaa agaaagcgat gtggtcatca
    21241 gtgacttgcc tgtcggctat tatcctgatg atgccgttgc gtcgcgtcat caagttgctt
    21301 ctagccaaga acatacttac gcccatcact tgctcatgga acaaggattt aagtacctta
    21361 agtcagatgg atatgctatt tttctagctc cgagtgattt gttgaccagt cctcaaagtg
    21421 atttgttgaa agtctggttg aaagaggagg caagtctggt tgctatgatt agtctgcctg
    21481 aaaatctctt tgctaatgct aaacaatcta agactatttt tatcctacag aagaaaagtg
    21541 aaatagcagt ggagcttttt gtttatccac ttgctagctt gcaagatgca agtgttttaa
    21601 tgaaatttaa agaaaatttt caaaaatgga ctcaaggtac tgaaatataa aatagatttt
    21661 gttataatag ttgaaaacgc ttaaaaaggg gtatcatgtt atgacaaaaa caattgcaat
    21721 caatgcagga agttcaagct taaaatggca attatactta atgccagagg aaaaagtatt
    21781 ggcgaaaggc ttgattgaac gtatcggttt gaaagattca atttcaactg taaaatttga
    21841 cggccgttct gaacaacaaa ttttggatat cgaaaatcat acacaagccg ttaaaatttt
    21901 attggatgac ttgattcgtt tcgatattat caaggcttat gacgagatta caggtgttgg
    21961 ccaccgtgtt gtagcaggtg gagaatattt caaagaatca acagttgttg agggagatgt
    22021 tttagaaaaa gttgaagagt tgagtttgtt ggctcctcta cacaacccgg ccaatgcagc
    22081 aggtgttcgt gccttcaagg aattgttgcc agacattacc agtgtagttg tttttgatac
    22141 ttccttccac acaagtatgc cagagaaagc ttatcgctac cctctaccaa caaaatatta
    22201 cacagaaaac aaggttcgta aatacggtgc tcatggtaca agtcaccagt ttgtagcagg
    22261 agaagctgca aaactcttgg gacgtccatt agaagacttg aagttaatta cctgtcatat
    22321 tggtaacgga ggctcaatta cagctgtgaa agccggcaaa tctgtagaca cttctatggg
    22381 gttcactcct cttggtggta ttatgatggg aacgcgtaca ggggatattg atccagctat
    22441 cattccttat ttaatgcaat atacagagga ttttaacaca ccagaagata tcagtcgtgt
    22501 tcttaaccgt gaatcaggtc ttttgggagt ttctgctaat tctagcgata tgcgcgatat
    22561 agaagcagct gtagcagaag ggaatcacga ggctagcttg gcttatgaaa tgtatgttga
    22621 ccgtatccaa aaacatatcg gtcagtacct tgcagtgcta aatggaacag atgccattgt
    22681 tttcacagca ggtgtcggtg aaaatgcaga gaatttccgt cgtgatgtaa tctcagggat
    22741 ttcgtggttt ggttgtgatg ttgatgatga aaagaatgtc tttggcgtta caggagacat
    22801 ctcaacagag gcagctaaaa tccgtgtctt ggttattcca acagatgaag aattagtcat
    22861 tgcccgtgac gttgaacgct tgaaaaaata agtgaaacta aaaaaatatt caatacaagg
    22921 agttgggaaa gttatttttc cagcttcttt ttctgatgaa attgtccaaa accttgctat
    22981 gattggcttt tttgaaaaat atggtataat agtagtaatt taatagatgg agttgagttt
    23041 tgaagaaaaa ctttcgtgta aaaagagaga aagattttaa ggcgattttc aaggagggga
    23101 caagttttgc taatcgcaaa tttgtggtct accaattaga aaaccagaaa aaccattttc
    23161 gagtaggtct atcagttagc aaaaaactgg ggaatgccgt cactagaaat caaattaagc
    23221 gacggattcg gcatattatc cagaatgcaa aagggagtct ggtagaagat gtcgactttg
    23281 ttgtcattgc tcgaaaagga gtcgaaacct tgggatacgc agagatggag aaaaatctac
    23341 tccatgtatt aaaattatca aagatttacc gggaaggaaa tgggagtgaa aaagaaacta
    23401 aagttgacta gtttgctagg actgtctctg ttaatcatga cagcctgtgc gactaatggg
    23461 gtaactagcg atattacagc cgaatcggct gatttttgga gtaaattggt ttacttcttt
    23521 gcggaaatca ttcgcttttt atcgtttgat attagtatcg gagtggggat tattctcttt
    23581 acggtcttga ttcgtacagt cctcttgcca gtctttcagg tgcaaatggt ggcttctagg
    23641 aaaatgcagg aagctcagcc acgcattaag gcgcttcgag aacaatatcc aggtcgagat
    23701 atggaaagca gaaccaaact agagcaggaa atgcgtaaag tatttaaaga aatgggtgtc
    23761 agacagtcag actctctttg gccgattttg attcagatgc cggttatttt ggccctgttc
    23821 caagccctat caagagttga ctttttaaag acaggtcatt tcttatggat taaccttggt
    23881 agtgtggata caacccttgt tcttccgatt ttagcagcag tattcacctt tttaagtact
    23941 tggttgtcca acaaagcttt gtctgagcga aatggcgcta cgactgcgat gatgtatggg
    24001 attccagtct tgatttttat ctttgcagtt tatgcgccag gtggagtcgc cctatactgg
    24061 acagtgtcta atgcttatca agtcttgcaa acctatttct tgaataatcc attcaagatt
    24121 atcgcagagc gcgaggccgt agtacaggca caaaaagatt tggaaaatag aaaaagaaaa
    24181 gccaagaaaa aggctcagaa aacgaaataa ataaggagga atctggtaat ggtagtattt
    24241 acaggttcaa ctgttgaaga agcaatccag aaaggattga aagaattaga tattccaaga
    24301 atgaaggctc atatcaaagt catttctagg gagaaaaaag gctttcttgg tctatttggt
    24361 aaaaaaccag cccaagtgga tattgaagcg attagtgaaa cgactgttgt caaagcaaat
    24421 caacaggtag taaaaggcgt tccgaaaaaa atcaatgatt tgaacgagcc tgtgaagacg
    24481 gttagtgaag aaaccgttga ccttggtcat gtagttgatg ctattaaaaa aatagaggaa
    24541 gaaggtcaag gtatttctga tgaagtcaag gctgaaatct taaaacatga aagacatgcc
    24601 agcactatct tagaagaaac tggtcacatt gagattttaa atgaacttca aatcgaggaa
    24661 gcgatgaggg aagaagcagg cgctgatgac cttgaaactg agcaagacca agctgaaagt
    24721 caagaactag aagacttggg cttgaaagtt gaaacgaact ttgatattga acaagtagct
    24781 acggaagtaa tggcttatgt tcaaacgatt attgatgaca tggatgttga ggctacactt
    24841 tcaaatgatt ataaccgtcg tagcatcaat ttgcaaattg atactaacga accaggtcgt
    24901 attatcggct accatggtaa agtcttgaag gccttgcaac tgttggctca aaattatctt
    24961 tacaactgct attcaagaac cttctatatc actattaatg tcaatgatta tgttgaacac
    25021 cgtgcagaag tcttgcagac ctatgcgcaa aaattggcga ttcgtgtttt agaagaagga
    25081 cgcagtcatc aaacagatcc aatgtcgaat agtgaacgca agattatcca ccgtattatt
    25141 tcacgtatgg atggcgtgac cagttactct gaaggtgatg agccaaatcg ctatgtcgtt
    25201 gtagatacag aataagtaaa atcagggttg acctgatttt ttgctagcta gaggaggtta
    25261 aactgatgtt gaataagata agagactatc tagacttttc tggtttgcag taccgtagtc
    25321 ctgataaagc gggagcagag cgagagaaga tgctggcatt ccgtcacaaa ggacaagagg
    25381 cccgaaaggc ttttacagaa ctggccaaag cctttcaagc aagccatcca gaatggcaac
    25441 tccaacagac tagtcagtgg atgaatcagg cccagcgttt gagaccacat ttttgggttt
    25501 atctacagag agacggacaa gtgacagaac ctatgatggc cttacgtttg tatgggacat
    25561 ctactgactt tggaatttct ttggaagtca gtttcatcga acgtaagaag gatgagcaaa
    25621 ctttagagaa acaggccaag attttagaca ttccaaccgt taaaggaatt tattatctag
    25681 cctactctga tggccaaagt caacggtggg aggcgaacga agaaaagcgt cgtactttac
    25741 gcgagaaggt gagaagtcaa gaagttcgaa aagttttagt gaaggtagat gttcctatga
    25801 cagaaaattc gtctgaagaa gaaatcgtag aaggcttatt gaagtcttat tctaaaattc
    25861 ttccctatta tctagctacg agaaaataag ataatttgta aaacatcata aatcatacag
    25921 tccaagagtg aacagtccgc tgtgtaattc ttggtctttt tgtttgcgct ttcgcattat
    25981 ataataaact tacaaaaaca attcaaaagg agaacaatta tggaagtcat ttcaagtgtt
    26041 ctaaattggt tttctagcaa tattttgcag aatcccgcat ttttcgtagg tttattggtg
    26101 ttgataggat atgcactttt gaaaaaacct gcccatgacg ttttttcagg gtttgttaaa
    26161 gcaacagtag ggtatatgtt gcttaacgtg ggtgctggtg gtttggttac aacctttcgt
    26221 ccaatcttag cagctcttaa ctacaaattc caaattggtg cagcggttat cgacccttac
    26281 tttggacttg ctgcagcaaa caacaaaatt gcagcagagt ttccagattt tgttggaact
    26341 gcaactacag ctctattgat tggttttgga ataaatatct tgctcgtagc tcttcgaaag
    26401 attacgaagg taagaaccct ctttattact ggtcacatca tggtacaaca agctgcaaca
    26461 gtatctctta tggttctatt cttagtacca caattgcgca atgcttacgg tacagcagcg
    26521 attggtatca tctgtggact ttactgggca gttagttcaa atatgactgt tgaggcaact
    26581 caacgcttga ctggtggtgg cggatttgcg attggtcacc aacagcaatt tgcaatctgg
    26641 tttgtagata aagtagcagg acgctttggt aagaaagaag aaagtttaga caatcttaaa
    26701 ttacctaagt tcctctcaat cttccacgat acagttgttg catctgctac cttgatgctc
    26761 gtattcttcg gagccattct tttaatcttg ggtccagaca ttatgtctaa taaagaagtc
    26821 atcacttcag gaactctatt caatcctgct aaacaagatt tctttatgta cattatccaa
    26881 acagccttta ccttctcagt ttacttgttc gttttgatgc aaggtgtccg aatgttcgta
    26941 tctgagttga caaacgcctt ccaaggtatt tcaaacaaat tgttgccagg ttcattccca
    27001 gcggttgacg ttgcagcttc ttatggattt ggttctccaa atgctgtcct gtcaggattt
    27061 atctttggtt tgattggtca attgattaca attgttttgc tcatcgtctt taaaaatccg
    27121 attcttatta ttacaggatt tgtaccagtg ttctttgaca atgcagccat tgcggtctac
    27181 gctgataaac gcggcggatg gaaagcggct gttatccttt cctttatatc aggtgtcctt
    27241 caagttgctc taggagctct ttgtgtggcc cttctcgatt tggcatctta tggtggctac
    27301 catggaaata tcgactttga attcccatgg cttggatttg gatatatctt caaatacctt
    27361 ggtattgttg gttatgtact tgtgtgtctc ttcttgcttg ttattcctca acttcaattt
    27421 gccaaagcaa aagataaaga gaaatattac aacggtgaag ttcaagaaga agcttagtat
    27481 ctagaaaagg agaaataaaa tggttaaagt attagcagcg tgcggaaatg gaatgggttc
    27541 atcaatggtt atcaagatga aggttgaaaa tgctctccgt aagcttaatc aaacagattt
    27601 tacagtcaat tcatgcagtg tcggtgaagc taaaggttta gcagtaggat atgacatcgt
    27661 aatcgcttct cttcatttga ttcaagaatt ggaagggcga actaatggga agttaattgg
    27721 gcttgataac ttgatggatg ataaagaaat caccgaaaaa ctcagtcaag cactacagta
    27781 aaaggttgga gggggctgga cagaaactga gagttatcgt ttctgtcctt ctccctcttt
    27841 aaataaagga ggcagatatg aatttaaaac aagctttaat tgacaacgac tcgatccgac
    27901 taggtttaga ggctaacgat tggaaagaag cagtcaaggt agcagtagat cccttgattg
    27961 aaagtggggc aattttgcca gagtattacg atgctatcat tgaatcgact gaagagtatg
    28021 ggccttacta tatcttgatg ccaggtatgg ctatgcccca cgctagacct gaagctggtg
    28081 tgcaaagtga tgccttttca ttaattacct tacaaaatcc tgttgtattt tcagatggga
    28141 aagaggtatc tgttttgttg gcactagcag caacaagttc aaaaattcac acaagtgtag
    28201 ccattccaca aattattgcc ctgtttgaat tagaagattc tattgcacgt ttacaggctt
    28261 gccagactaa agaagatgtc ttggctatga ttgaagaatc taaggatagc ccttatctcg
    28321 aaggattgga tttggaaagt tagaaagagg aataaagaaa tgacaaaaag aatacctaat
    28381 ttacaagttg cattagacca ttcagacttg caaggagcga ttaaagcagc tgtttctgtt
    28441 ggtcaggaag tagatattat cgaagctgga actgtttgct tgcttcaagt tggaagtgaa
    28501 ctggctgaag tcttgcgtag ccttttccca gataagatta ttgtggcaga cacaaaatgt
    28561 gctgatgctg gtggaacagt tgctaaaaat aatgcggttc gtggagcaga ctggatgact
    28621 tgtatctgtt gtgcaaccat ccctactatg gaagcagctc taaaggctat caagactgaa
    28681 cgaggagaac gaggcgaaat ccagatcgag ctttatggcg attggacttt tgaacaagct
    28741 cagctttggc tagatgcagg tatctcacaa gctatttatc accaatctcg tgatgctctt
    28801 cttgctggtg aaacttgggg tgaaaaagac cttaataagg ttaaaaaact cattgacatg
    28861 ggcttccgtg tatctgtaac aggtggtcta gatgtagata ctctcaaact ctttgaaggt
    28921 gttgatgtct ttacctttat cgcaggtcgt ggaattacag aggctgtgga tccagcagga
    28981 gcagcgcgtg ccttcaagga tgaaatcaaa cgaatttggg ggtaaatcat ggtacgtcca
    29041 attggaattt atgaaaaggc aaccccaaca cactttactt ggctagaacg tttaaatttt
    29101 gccaaggagt taggctttga ttttatcgag atgtctattg acgaacgtga cgagcgttta
    29161 gcaagacttg actggagtaa ggaagaacgc ttggaagttg tcaaagaaat ctatgaaact
    29221 ggtgttcgta ttccttctat ctgtttttca ggccatcgtc gctacccatt gggatcaaaa
    29281 gattcagttc tagaggaaaa atctctagaa ctcatgaaaa aatgtatcga attagctcaa
    29341 gacttgggag ttcgtacgat tcaattagct ggttacgatg tttactatga ggaaaagtca
    29401 ccccagacac gccaacgttt tatcaaaaat ttgagaaaag cctgtgactg ggctgaagaa
    29461 gctcaggtgg tacttgctat tgaaattatg gatgatcctt tcatcagtag catcgaaaaa
    29521 tatttggcta tagaaaaaga gattgactct cccttcctct ttgtatatcc agatattggt
    29581 aatgtgtctg catggcataa tgatatctat agtgagtttt atcttggtca tcatgccatc
    29641 gcagctctcc atctcaagga tacttatgca gtgacagaaa gttcaaaggg ccagttccga
    29701 gatgtacctt tcgggcaagg ttgtgtcaaa tgggaagaag ctttcgatat tttaaaggaa
    29761 accaattata atggaccttt cctaatcgaa atgtggtctg aaaattgtga aacagtagaa
    29821 gaaacacgcg cagccattca agaggcgcaa gcttttctct atccactcat taagaaagca
    29881 ggtttgatgt aagatgaatc aagtaatcaa tgctatgcgt aaacgagtct gtgatgccaa
    29941 tcaatcattg ccaaaacatg gacttgtcaa atttacctgg gggaatgtat ctgaagttaa
    30001 tcgcgaactc ggtgtcattg ttatcaaacc atcaggcgtg gattatgacg aattgacacc
    30061 tgaaaacatg gtagtgactg atctagatgg taagatccta gaaggggatt taagaccatc
    30121 ttccgacctc ccaactcatg tgcaattata taaggcttgg tcagaaattg gtagtgtggt
    30181 tcacacccat tcgacagaag ctgttggttg ggctcaggca ggtcgtgata ttcctttcta
    30241 cggaacaacc catgcagatt atttctacgg ttcaatccct tgcgcccgta gtttgaccaa
    30301 ggacgaagta gaagtggcct atgaaaaaga tactggcctg gttatcgtag aagagtttga
    30361 acatcgcgga cttaacccgg ttgaagtacc aggaattatt gtacgcaatc acggtccatt
    30421 cacctggggc aaaaatccag agaatgctgt ttatcactct gtcgtactag aggaagtatc
    30481 aaagatgaat cgctttacag aacaaatcaa tccaagagtt ggacctgctc cccagtacat
    30541 actagaaaaa cactaccaac gtaaacatgg accaaatgct tattatggtc aaaagtaaga
    30601 acgatgaagg aggagaaaaa gataaattta gctcctcttt ttacatttga tttttattga
    30661 gagtaaagtt ggaattgaag taattttaaa agatttttta gaaatagcgc ttgatatata
    30721 tatggtaaaa taaaaagaat tgctgtgata tcaatagatt tgggggattt tttaatatgg
    30781 tactggataa ggcaagttgt gatttgcttc aatatttgat ggatcaagaa acgtccaaaa
    30841 cgattatggc gatttcgaaa gatttgaaag agtcaagaag gaaaatttat tatcacattg
    30901 acaaaatcaa tgctgctctg ggtgacgagg cgcttcacat cattagtatt ccacgaattg
    30961 gtattcactt aacggaagag cagagagatg cttgttgtaa actattatcg gaagtagatt
    31021 cgtacgatta tatcatgagt gcgcatgaac gtatgatgat aatgttacta tggataggta
    31081 tttctaaaga acgtattacg attgaaaaat tgatagagtt aacagaggta tctaggaata
    31141 ctgttctcaa tgatttgaat agtattcgtt atcaactaac tttggaacaa tatcaggtga
    31201 tcttgcaagt gagcaagtca cagggatacc accttcatgc ccaccctctt aataaaattc
    31261 agtatcttca atcgcttcta tatcatattt ttatggaaga aaatgccact tttgtatcta
    31321 ttttagaaga taagatgaaa gagaggttag atgatgagtg tttgctttct gttgaaatga
    31381 accaattttt taaggaacag gttcctttag ttgaacaaga tttagggaag aaaataaacc
    31441 atcatgaaat aacttttatg ttgcaggttc taccttattt gctgttaagc tgtcataatg
    31501 ttgaacagta tcaagaaaga catcaggata tagagaaaga attttctttg ataagaaaaa
    31561 gaatagagta tcaggtgtct aagaaattag gagaacggtt gtttcaaaag tttgaaattt
    31621 ctttgtcagg acttgaagtt tctcttgtag ctgttctcct cctctcctat cgtaaagatt
    31681 tggatattca tgcagaaagt gatgattttc ggcaattaaa acttgcttta gaagaattta
    31741 tctggtattt tgaatcacaa atccgaatgg agattgagaa caaggatgat ttgttacgaa
    31801 atttgatgat ccactgtaaa gccttgttat ttagaaagac ttacggtatt ttttctaaaa
    31861 atcctctaac aaaacaaatt cgatccaagt atggagaatt atttttagtc actagaaaat
    31921 ctgcggaaat tttagaagga gcatggttta ttcggctaac agacgatgat attgcctatt
    31981 tgacgattca tattggagga tttttaaaat atacaccatc gtctcaaaaa aatatgaaaa
    32041 aagtttatct cgtttgtgat gaaggtgttg cggtttcgag acttttgctg aaacaatgca
    32101 aactttattt tccaaatgag caaattgaca ctgtatttac aacagaacaa tttaagagtg
    32161 tggaagatat tgcacaagtt gatgtagtga ttactactaa tgatgatttg gatagcagat
    32221 ttccgatttt aagggttaat cctatccttg aagcagaaga tattttgaaa atgctagact
    32281 atcttaaaca caatatattt cgtaataaga gcaaaagttt cagtgaaaat ctttctagtc
    32341 ttatttcgtc ttatattgta gacagcaagt tggctagtaa gttccaagaa gaggttcaaa
    32401 cacttataaa tcaagaaata gtagttcaag cttttttgga agatatttga aggacagtcc
    32461 aatgatgaac acaaacctgt gtttttcttg gtctttttta gtgttttgaa gggtggtata
    32521 ctaatctcaa agataacaat tatatccaaa ggaggcaaca tatgccaaac gtcaaagaaa
    32581 ttacaagaga gtcatggatt ttagccactt tcccagagtg gggaacatgg ttgaacgaag
    32641 aaatcgaaga agaagtcgta cctgaaggca actttgccat gtggtggcta ggcaactgtg
    32701 gtacttggat taagacacca gctggtgcta acgttgtcat ggacctttgg tcaaaccgtg
    32761 gaaaatcaac caaaaaagtg aaagatatgg ttcgtgggca ccaaatggca aatatggcag
    32821 gtgttcgtaa gttgcaacca aacttgcgtg ttcagccaat ggttatcgat ccatttgcta
    32881 tcaacgaact agactattac ttagtttcac acttccacag tgatcatatc gacccataca
    32941 cagctgcagc aattctcaac aatcctaagt tagagcatgt taagtttatc ggtccttacc
    33001 actgtggacg aatctgggaa ggatggggtg ttccaaaaga acgtatcatc gttgttaaac
    33061 caggtgacac tatcgaatta aaagatatga agattcatgc agtagaatca tttgaccgta
    33121 cttgcttggt aactctccca gtgaacggtg ctgatgagac aggcggtgaa cttgctggct
    33181 tggctgttac agatgaagaa atggctcaaa aggctgttaa ctatatcttt gaaacaccag
    33241 gtggaaccat ctatcatggt gcagattctc acttctcaaa ctattttgca aaacatggta
    33301 aagactttaa aattgatgtt gctttgaata actatggtga aaatccggta ggtatccaag
    33361 acaaaatgac atctatcgac cttcttcgta tggcagaaaa tctgcgtacc aaagtcatta
    33421 tcccagttca ctatgatatc tggtctaact tcatggcttc tactaatgag attctagaac
    33481 tttggaaaat gcgaaaagat cgcttgcaat acgatttcca tccatttatc tgggaagttg
    33541 gcggtaagta cacttatcct caagatcaac acttagtaga ataccatcat ccacgtggtt
    33601 ttgatgattg ttttgaacaa gactctaaca ttcaatttaa agctttgcta taatataaaa
    33661 atattctttg gaggttatcc gtatgttgca tgatacggat aattttcata taatagtaaa
    33721 atagaatgtg tgattcaata atcacctcaa atagaaagga aattctatgt caaatctatc
    33781 tgttaatgca attcgttttc taggtattga cgccattaat aaagccaact caggtcatcc
    33841 aggtgtggtt atgggagcgg ctccgatggc ttacagcctc tttacaaaac aacttcatat
    33901 caatccagct caaccaaact ggattaaccg cgaccgcttt attctttcag caggtcatgg
    33961 ttcaatgctc ctttatgctc ttcttcacct ttctggtttt gaagatgtca gcatggatga
    34021 gattaagagt ttccgtcaat ggggttcaaa aacaccaggt cacccagaat ttggtcatac
    34081 ggcagggatt gatgctacga caggtcctct agggcaaggt atttcaactg ctactggttt
    34141 tgcccaagca gaacgtttct tggcagccaa atataaccgt gaaggctaca atatctttga
    34201 ccactatact tacgttatct gtggagacgg agacttgatg gaaggtgtct caagcgaggc
    34261 agcttcatac gcaggtttgc aaaaacttga taagttggtt gttctttatg attcaaatga
    34321 tatcaacttg gatggtgaga caaaggattc ctttacagaa agtgttcgtg accgttacaa
    34381 tgcctacggt tggcatactg ccttggttga aaatggaaca gacttggaag ccatccatgc
    34441 tgctatcgaa acagcaaaag cttcaggcaa gccatctttg attgaagtga agacggttat
    34501 tggatacggt tctccaaaca aacaaggaac taatgctgta cacggcgccc ctcttggagc
    34561 agatgaaact gcatcaactc gtcaagccct cggttgggac tacgaaccat ttgaaattcc
    34621 agaacaagta tatgctgatt tcaaagaaca tgttgcagac cgtggcgcat cagcttatca
    34681 agcttggact aaattagttg cagattataa agaagctcat ccagaactgg ctgcagaagt
    34741 agaagccatc atcgacggac gtgatccagt cgaagtgact ccagcagact tcccagcttt
    34801 agaaaatggt ttttctcaag caactcgtaa ttcaagtcaa gatgccttga atgttgtggc
    34861 agctaaatta ccaacctttc taggtggatc agctgacctt gctcactcaa acatgactta
    34921 tatcaagacg gatggacttc aagacgatgc caatcgcttg aatcgtaaca ttcagtttgg
    34981 tgttcgtgaa tttgcaatgg gaacaatctt gaacgggatg gcccttcatg gtggacttcg
    35041 tgtatacggt ggaactttct tcgtcttctc tgactatgtg aaggcagctg tccgcttgtc
    35101 agccttacaa ggacttcctg tgacttatgt ctttacccat gattcaatcg cagttgggga
    35161 agatggtccg actcacgaac cagttgagca tttagcaggt cttcgtgcta tgccaaatct
    35221 aaatgttttc cgtccagcag atgcgcgtga aacgcaagca gcttggtacc ttgcagtgac
    35281 aagtgagaaa acaccaactg cccttgtctt gacacgtcaa aacttgactg ttgaagatgg
    35341 aacagacttc gacaaggttg ctaaaggtgc ttatgttgta tatgaaaatg cagccgactt
    35401 tgataccatc ttgattgcga caggttcaga ggttaatctt gctgtctcag ctgctaaaga
    35461 attggctagt caaggcgaaa aaatccgcgt agtcagcatg ccatctacag atgtctttga
    35521 taaacaagat gcagcttaca aggaagaaat tcttccaaat gcagtccgcc gtcgtgttgc
    35581 agtcgaaatg ggtgcaagtc aaaactggta caaatatgtt ggtctcgatg gtgccgttct
    35641 aggtattgat accttcggag cctctgcccc agcaccaaaa gtattggcag aatatggctt
    35701 tactgtagaa aatcttgtaa aaattgttcg aaacttgaaa taatcctaaa aatcagggcg
    35761 taagctctgg tttttcttac cagaaaagta aggtacaatc ttgtaaaagt agctgaaatt
    35821 tgatatagta gtcctatgta aaagacaaag gagaaaacaa tgaatccaaa tattactttt
    35881 ttaatcatgc ttgtaggtat gatggccttg atgttcttta tgcaacgttc tcaaaagaaa
    35941 caagctcaaa agcgtatgga aagcttaaat aaactacaaa aaggctatga agtgattaca
    36001 atcggtggac tttatggaac agtcgatgaa gtagatacgg agaagggaac aatagttctt
    36061 gacgtagatg gagtttactt gacttttgaa ctagctgcta tcaagacagt attaccgctg
    36121 aaagaaacag cttcactaga aggcgcaatt gaaaaataag acgggatcac gaactcccgt
    36181 ttttctataa aagaaaggaa atgggatgaa aaaattagtc tttgtctgtc tgggaaatat
    36241 ttgccgtagc cctatggccg agtttgttat gaaatcaatg acagataact acgaaatcca
    36301 aagtcgagca acttcctctt gggaacatgg caatccgatt cataagggga ctcagggaat
    36361 ttttcaacag tatgagattc tttatgacaa gaacaagaca tcgcttcaga ttagtaagga
    36421 agattttgaa gcctttgatt atattatcgg aatggacgct tcaaatattt ctgacttacg
    36481 tcagatgtgt ccagtagact gtcaagataa gatttactca ttttcatctg aaagtgttcc
    36541 agacccttgg tatacaggag attttgaaga aacctatcga cgtgttcaag agggctgtca
    36601 agcttggtta gaacgtttag aaaaggagag ttaaggtgga aaatcttacg aatttttacg
    36661 aaaagtatcg tgtctatctg actcgtccac gtttagagct tttggcagta gttaccattg
    36721 ttttctgtgc tgtactcgtc ttttttctaa atattccagg aaaaggtgtc ttaaaactcg
    36781 ataatggaac gattgtttat gatggcagtc ttgtccgtgg taaaatgaat ggtcaaggta
    36841 ccattacctt ccaaaatgga gaccaatata caggtggctt caacaatgga gccttcaacg
    36901 gaaaaggtac ctttcaatct aaagaaggct ggacctacga aggtgatttt gtaaatggtc
    36961 aggctgaagg aaaagggaaa ctaacaacag aacaagaagt cgtttatgaa ggaactttta
    37021 aacaaggcgt ttttcaacaa aaataaagcc tccttatcca aaggaggtat tattagaacc
    37081 acaaggtaag cgcttacctg taaatccctt tctttccaaa tccctcttcc aagcaagttt
    37141 gtgaaataaa aaatatttga aataaatttc acaaacttca aagataaaac ctgataagaa
    37201 aagaaaatga gaaaagtttc acaagagttt aaaaattctt tgtgaaatgt ttatgaaact
    37261 gtttacaaag ttgaaataat gcgttataat aaacttgtga aaaaattaac aaaggatatc
    37321 gttccttgaa agctatggag gaaaatatgg ctgataaaaa aactgtgaca ccagaggaaa
    37381 agaaactcgt tgctgaaaaa cacgtagatg agttggttca aaaagctcta gttgcccttg
    37441 aagaaatgcg taaattggat caagagcaag ttgactacat cgttgctaaa gcatcagtag
    37501 cagctttgga tgcccacgga gaattggctt tacatgcctt tgaagaaaca ggacgtggtg
    37561 tatttgaaga taaagcaact aagaacttgt ttgcctgtga acacgtagta aacaacatgc
    37621 gtcacactaa gacagttggc gttatcgaag aagacgatgt aacaggattg actcttattg
    37681 ctgaaccagt tggtgttgtt tgtggtatta ctccaacaac aaacccaaca tcaacagcaa
    37741 tcttcaaatc attgatttca ttgaagacac gtaacccaat cgtctttgcc ttccatccat
    37801 cagcacaaga atcatctgct catgcagctc gtatcgtccg cgatgcagct atcgcagctg
    37861 gtgctcctga aaactgtgtg caatggatta ctcaaccatc tatggaagca acaagtgccc
    37921 ttatgaacca cgaaggtgtt gcgacaatcc ttgcaacagg tggtaatgcc atggttaagg
    37981 cggcttattc atgtggtaaa ccagctcttg gggtaggtgc cggaaacgtt ccagcttatg
    38041 ttgaaaaatc agcaaacatt cgtcaagcag cacacgatat cgtcatgtct aaatcatttg
    38101 ataacggtat ggtctgtgca tctgaacaag cagttatcat tgataaagaa atttacgatg
    38161 aatttgtagc agagttcaaa tcttaccaca cttactttgt aaacaaaaaa gaaaaagctc
    38221 ttcttgaaga gttctgcttc ggcgtcaaag caaacagcaa aaactgtgct ggtgcaaaat
    38281 tgaacgctga catcgttggt aaaccagcaa cttggattgc agaacaagca ggatttacag
    38341 ttccagaagg aacaaacatt cttgctgcag aatgtaaaga agttggcgaa aatgagccat
    38401 tgactcgtga aaaattgtca ccagttattg cagttttgaa atctgaaagc cgtgaagatg
    38461 gtattactaa ggctcgtcaa atggttgaat ttaacggtct tggacactca gcagctatcc
    38521 acacagctga cgaagaattg actaaagaat ttggtaaagc tgttaaagct attcgtgtta
    38581 tctgtaactc accttctact tttggtggta ttggggacgt ttacaatgcc ttcttgccat
    38641 cattgacact tggatgtggt tcttacggac gcaactcagt tggggataac gttagtgcca
    38701 ttaacctctt gaatatcaaa aaagtcggaa gacggagaaa taacatgcaa tggatgaaac
    38761 ttccttcaaa aacatacttt gaacgtgatt caattcaata ccttcaaaaa tgtcgtgacg
    38821 ttgaacgtgt catgatcgtt actgaccatg ccatggtaga gcttggtttc cttgatcgta
    38881 tcatcgaaca actggacctt cgtcgcaata aggttgttta ccaaatcttt gcggatgtag
    38941 aaccggatcc agatatcaca actgtaaacc gtggtactga gattatgcgt gccttcaaac
    39001 cagataccat catcgcactc ggtggtgggt ctccaatgga tgctgccaaa gtaatgtggc
    39061 tcttctacga gcaaccagaa gtggacttcc gtgaccttgt ccaaaaattc atggatatcc
    39121 gtaaacgtgc cttcaagttc ccattgcttg gtaagaagac taaattcatc gcgattccaa
    39181 ctacatctgg tacaggatct gaagtaacac catttgccgt tatctctgat aaagcaaaca
    39241 accgtaaata cccaatcgct gactactcat tgacaccaac tgtggcaatc gtagatcctg
    39301 ctttggtatt gacagttcca ggatttgttg ctgctgatac tggtatggac gtattgactc
    39361 acgcgacaga agcatacgta tcacaaatgg ctagtgacta cactgatggt ttagcacttc
    39421 aagccattaa attggtcttt gaaaatctcg aaagctcagt taagaatgca gacttccact
    39481 cacgtgagaa aatgcataac gcttcaacaa tcgctggtat ggcctttgcc aatgccttcc
    39541 taggtatttc tcactcaatg gcccataaga ttggtgcgca attccacaca atccacggtc
    39601 gtacaaatgc catcttgctt ccatacgtta tccgttacaa cggtacacgt ccagctaaga
    39661 cagcaacatg gcctaagtac aactactacc gtgcagatga aaaataccaa gatatcgcac
    39721 gcatgcttgg acttccagct tctactccag aagaaggggt tgaatcttac gcaaaagctg
    39781 tctacgaact cggtgaacgt attgggatcc aaatgaattt tagagaccaa ggaattgacg
    39841 aaaaagaatg gaaagaacat tctcgtgaat tagccttcct ggcttatgaa gaccaatgtt
    39901 caccagctaa cccacgtctt ccaatggtag accatatgca agaaatcatc gaagatgcat
    39961 actatggcta caaagaaaga ccaggacgcc gtaaataatt gtttatcagt ctagaagcaa
    40021 gacaaaaact caatttgagg gaaagatcca gtaatttttc tatgataaaa ggcatcctat
    40081 caaggttttt gaacacctga taggatgcct ttttatgata ttgaggcctt tttgcccttt
    40141 ttgaaaaact agaatagaaa caaaatatat aatagattga aactagaata gtacacatct
    40201 gcttctaaaa cattgttaga attcgatttg actgtcctga tcgatttgtc ctgttcttat
    40261 ttcattttga tatataaaaa atat
//
LOCUS       DAVKEV010000020        39917 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVKEV010000020 DAVKEV010000000
VERSION     DAVKEV010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39917
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.020"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            343..1386
                     /locus_tag="VWZ68_001040"
     CDS             343..1386
                     /locus_tag="VWZ68_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEU9372074.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIIARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            1553..3640
                     /gene="topA"
                     /locus_tag="VWZ68_001041"
     CDS             1553..3640
                     /gene="topA"
                     /locus_tag="VWZ68_001041"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEU9372075.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEENIK"
     gene            3746..4105
                     /locus_tag="VWZ68_001042"
     CDS             3746..4105
                     /locus_tag="VWZ68_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEU9372076.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4198..4830
                     /locus_tag="VWZ68_001043"
     CDS             4198..4830
                     /locus_tag="VWZ68_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEU9372077.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGVLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQVGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            4874..5530
                     /locus_tag="VWZ68_001044"
     CDS             4874..5530
                     /locus_tag="VWZ68_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEU9372078.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5549..6169
                     /locus_tag="VWZ68_001045"
                     /pseudo
     CDS             5549..6169
                     /locus_tag="VWZ68_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
     gene            6197..6631
                     /locus_tag="VWZ68_001046"
     CDS             6197..6631
                     /locus_tag="VWZ68_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEU9372079.1"
                     /translation="MVAGSMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            6643..7680
                     /gene="leuB"
                     /locus_tag="VWZ68_001047"
     CDS             6643..7680
                     /gene="leuB"
                     /locus_tag="VWZ68_001047"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEU9372080.1"
                     /translation="MAKKIVALVGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAWPPLPDETLKASREADAILLATIGSPQYDGAVVRPEQGLMTLRKELNLYAN
                     IRPVKIFDSLKHLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFSDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIHGSV
                     PDIAGQGIANPISMILSVSMMLRDSFGGYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            7677..7946
                     /locus_tag="VWZ68_001048"
     CDS             7677..7946
                     /locus_tag="VWZ68_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEU9372081.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            7950..8309
                     /gene="leuD"
                     /locus_tag="VWZ68_001049"
     CDS             7950..8309
                     /gene="leuD"
                     /locus_tag="VWZ68_001049"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEU9372082.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8528..8671
                     /locus_tag="VWZ68_001050"
     CDS             8528..8671
                     /locus_tag="VWZ68_001050"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372083.1"
                     /translation="MTSDKAGLERKFAAKEGKRNKPGVVLCGSMDELCALAQLNPKIE
                     AFY"
     gene            8690..8944
                     /locus_tag="VWZ68_001051"
     CDS             8690..8944
                     /locus_tag="VWZ68_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372084.1"
                     /translation="MLLGCILPWKPEAFEKLKAYGDGREELMTDVRGTSCFVIKFGKA
                     GEQLAAKLWEEGKMVYASYASMTKRLKLAMRARCNGVYGR"
     gene            8934..9095
                     /locus_tag="VWZ68_001052"
     CDS             8934..9095
                     /locus_tag="VWZ68_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372085.1"
                     /translation="MVDKDGKLIPEQGGARSTSPAPVVIRKGLDIDKIMMHLSDTFNL
                     WDYRQVEYY"
     gene            9258..9621
                     /locus_tag="VWZ68_001053"
                     /pseudo
     CDS             9258..9621
                     /locus_tag="VWZ68_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828316.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
     gene            9597..9911
                     /locus_tag="VWZ68_001054"
     CDS             9597..9911
                     /locus_tag="VWZ68_001054"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372086.1"
                     /translation="MDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAM
                     VTKLLCIYSEGDSFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVPKLILSWSH
                     RN"
     gene            9971..11188
                     /locus_tag="VWZ68_001055"
     CDS             9971..11188
                     /locus_tag="VWZ68_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEU9372087.1"
                     /translation="MDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEIAKELTD
                     GNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKETQLIGG
                     QDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLPSKYVYE
                     LYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEINRGEIS
                     KIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDRSVDTFD
                     FAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSHYHIGPS
                     YFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQKDQAVA
                     DDNEGDENDDADY"
     gene            11175..12491
                     /locus_tag="VWZ68_001056"
     CDS             11175..12491
                     /locus_tag="VWZ68_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEU9372088.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            12666..13652
                     /locus_tag="VWZ68_001057"
     CDS             12666..13652
                     /locus_tag="VWZ68_001057"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEU9372089.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            13716..13787
                     /locus_tag="VWZ68_001058"
     tRNA            13716..13787
                     /locus_tag="VWZ68_001058"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13749..13751,aa:Arg,seq:ccg)
     gene            13970..14668
                     /locus_tag="VWZ68_001059"
     CDS             13970..14668
                     /locus_tag="VWZ68_001059"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEU9372090.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            14659..18198
                     /gene="smc"
                     /locus_tag="VWZ68_001060"
     CDS             14659..18198
                     /gene="smc"
                     /locus_tag="VWZ68_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEU9372091.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLATLEDKRSS
                     LSQEKSDKESSLALLEENLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKAGQQKAELETAKEQVQK
                     LLADYQVCAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLEIILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDLLKR
                     NRSGRATFLPLTTIKARTISSQNQDTIAASPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELNRLSEGEWQADKEKCQERLTTITSEKNNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTDLLSQQADEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNLDAIEQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEVIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            18195..18989
                     /locus_tag="VWZ68_001061"
     CDS             18195..18989
                     /locus_tag="VWZ68_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9372092.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLVSYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEDGEAWVNENVPGVKAMTTGFESIDIVLDYVDKGVAIVELVKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            18989..19807
                     /locus_tag="VWZ68_001062"
     CDS             18989..19807
                     /locus_tag="VWZ68_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9372093.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLQAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            19811..21100
                     /gene="ftsY"
                     /locus_tag="VWZ68_001063"
     CDS             19811..21100
                     /gene="ftsY"
                     /locus_tag="VWZ68_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEU9372094.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTVEENNSEVLEPEAPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDVLRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVTEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(21146..22633)
                     /locus_tag="VWZ68_001064"
     CDS             complement(21146..22633)
                     /locus_tag="VWZ68_001064"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEU9372095.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(22782..23522)
                     /locus_tag="VWZ68_001065"
     CDS             complement(22782..23522)
                     /locus_tag="VWZ68_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9372096.1"
                     /translation="MVKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(23522..25687)
                     /locus_tag="VWZ68_001066"
     CDS             complement(23522..25687)
                     /locus_tag="VWZ68_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU9372097.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            25857..26810
                     /locus_tag="VWZ68_001067"
     CDS             25857..26810
                     /locus_tag="VWZ68_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9372098.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            26887..28875
                     /gene="uvrB"
                     /locus_tag="VWZ68_001068"
     CDS             26887..28875
                     /gene="uvrB"
                     /locus_tag="VWZ68_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEU9372099.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            28885..29448
                     /locus_tag="VWZ68_001069"
     CDS             28885..29448
                     /locus_tag="VWZ68_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9372100.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNIGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            29414..29902
                     /locus_tag="VWZ68_001070"
     CDS             29414..29902
                     /locus_tag="VWZ68_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9372101.1"
                     /translation="MTVIIKSMETPKEIEGKSLVHWQTWRESYDDLLPAEFQDTMTLE
                     RCRFFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            29976..30443
                     /locus_tag="VWZ68_001071"
     CDS             29976..30443
                     /locus_tag="VWZ68_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU9372102.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(30440..30955)
                     /locus_tag="VWZ68_001072"
     CDS             complement(30440..30955)
                     /locus_tag="VWZ68_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEU9372103.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(30967..31494)
                     /locus_tag="VWZ68_001073"
     CDS             complement(30967..31494)
                     /locus_tag="VWZ68_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9372104.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(31776..32339)
                     /locus_tag="VWZ68_001074"
     CDS             complement(31776..32339)
                     /locus_tag="VWZ68_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9372105.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(32323..32874)
                     /gene="coaC"
                     /locus_tag="VWZ68_001075"
     CDS             complement(32323..32874)
                     /gene="coaC"
                     /locus_tag="VWZ68_001075"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEU9372106.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(32886..33575)
                     /gene="coaB"
                     /locus_tag="VWZ68_001076"
     CDS             complement(32886..33575)
                     /gene="coaB"
                     /locus_tag="VWZ68_001076"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEU9372107.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            33805..35475
                     /locus_tag="VWZ68_001077"
     CDS             33805..35475
                     /locus_tag="VWZ68_001077"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEU9372108.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKSQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            35803..36978
                     /gene="mutY"
                     /locus_tag="VWZ68_001078"
     CDS             35803..36978
                     /gene="mutY"
                     /locus_tag="VWZ68_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEU9372109.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            37033..37737
                     /locus_tag="VWZ68_001079"
     CDS             37033..37737
                     /locus_tag="VWZ68_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9372110.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            37730..39079
                     /gene="vicK"
                     /locus_tag="VWZ68_001080"
     CDS             37730..39079
                     /gene="vicK"
                     /locus_tag="VWZ68_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEU9372111.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            39081..39890
                     /locus_tag="VWZ68_001081"
     CDS             39081..39890
                     /locus_tag="VWZ68_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU9372112.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
BASE COUNT        12261 a         7098 c         8906 g        11652 t
ORIGIN      
        1 gtagagatta caaggcttgt ttaagaaaga attcaaagac cttgacaaat aaaaataaaa
       61 tggttattat aaaaaatggt ctgaaataga tgatgatact tttcgaaaat ctttttacat
      121 cagctcagct ttgccttgct gtgttttgag caagctacgg ttagcttccg agtttgattt
      181 tcatttacta gaaatgaaac tgatgagaga tatcagtaga catctgagtc aggatattat
      241 ggaaaatgat aaaaagagct cgtgagattg gcatatcaga ctactaaagt attgagtttg
      301 ttaggatttt agcgactagt tagctgggaa aggaagatat ttgtgacaaa taataaactg
      361 tattcgttga tagaatttag aaataaaata tatgaagaat tagaactttc cagaagtgat
      421 ttagcgattt tactatgtgc catgcttatc gcctctatcg gattaaatat ggattcgact
      481 cccgtgatta ttggagccat gttaatctct cctttgatga cacctattct gggagtgggg
      541 ctctctctag ctatatttga ttttaaattg ttaagaaaat cttttaaaat attagctatt
      601 caaattcttg ccagtctaat agcttcaaca ctttattttt atctttctcc catttcgtat
      661 gctagttcgg agattattgc tagaacctct ccgactattt gggatgttct cattgctttt
      721 gtaggaggga tagcaggtat tattggtgct aggaaaaaag agaccaataa tattgttcct
      781 ggtgttgcta ttgcaaccgc cttgatgcct cctctttgta cagtaggtta tgctattgct
      841 tctgctaatc taaaatttat cataggctcc tcttacctat tcctcatcaa ttgtagcttt
      901 attgtcattg cgacttatat aggtgttagg ttgatgatgg ttaagaaaca ttattttaaa
      961 gataatgaag aagactctaa aatgcgtagg attttgcttc tagttgctgt tttgctgatg
     1021 attccgagtt tcatctctgc aacgacttta gtgagagaaa cgttgaaaaa agagtccctt
     1081 aagaaattta tatcagagca gtttcagggg cataatattt tgaaaaaaac ctattctaaa
     1141 aagactcata ccctaaagct aaccatttca ggaaattatt tgacagaaga agaactcgat
     1201 atgatttcaa gtaagagagg tgactatggt ttaagtgatg tttctgttca agtttcacaa
     1261 ttgtctgatt cagaacaact tagtaaggaa gaactggtgg agtatttctt ccagtatatc
     1321 aaggataagg aagcaaaaga aaaggaaaaa gctaataagt tttatacaga gtctgaggag
     1381 caataatttc ttgagaatag ctggtttttc tcgtgagtct tctatgtata tcaaaggaag
     1441 actgaggttt taagtataaa acttttcttc tattatagta gctaagtctt gacagggttc
     1501 aaaaaatggt ttacacttta taaagtttat tactttgaaa aggtgtgata ctgtggctac
     1561 ggcaacaaaa aagaaaaaat caacagttaa aaaaaatcta gtcatcgtgg agtcgcctgc
     1621 taaggccaag acgattgaaa aatatctagg cagaaactac aaggttttag ccagtgtcgg
     1681 gcatatccgt gatttgaaga aatccagtat gtccgttgat attgaaaata attatgaacc
     1741 gcaatatatc aatatccgag gaaaaggccc tcttatcaat gacttgaaaa aagaagctaa
     1801 aaaagctaat aaagtttttc tcgcgagtga cccggaccgt gaaggagaag cgatttcttg
     1861 gcatttggcc catattctca acttggatga aaatgatgcc aaccgtgtgg tcttcaatga
     1921 aatcaccaag gatgcagtca aaaatgcttt taaagaacct cgtaagatcg atatggactt
     1981 ggtcgatgcc caacaagctc gtcggatctt ggatcgcttg gtagggtatt cgatttcgcc
     2041 tattttgtgg aagaaggtca agaagggctt gtcagcaggt cgcgttcagt ccattgccct
     2101 taaactcatc attgaccgtg aaaatgaaat caatgccttc cagccagaag aatactggac
     2161 agttgatgct gtctttaaaa agggaaccaa acaatttcat gcttccttct atggagtaga
     2221 tggtaaaaag atgaaactga ccagcaatga cgaagtcaag gaagtcttgt ctcgtctgac
     2281 tagtaaagac ttttcagtag atcaggtgga taagaaagag cgcaagcgca atgctccttt
     2341 accctatacc acttcatcta tgcagatgga tgctgccaat aaaatcaatt tccgtactcg
     2401 aaaaaccatg atggttgccc aacagctcta tgaaggaatt aatatcggtt ctggtgttca
     2461 aggtttgatt acctatatgc gtaccgattc gactcgtatc agtcctgtag cgcaaaatga
     2521 ggcggcaagc ttcattacgg atcgttttgg tagtaagtat tctaagcacg gtagcaaggt
     2581 caaaaacgca tcaggtgctc aggatgccca tgaggctatt cgtccgtcaa gtgtctttaa
     2641 tacaccagaa agcatcgcta agtatctgga caaggatcag ctcaagctat atacccttat
     2701 ctggaatcgt tttgtggcta gccagatgac agcggccgtt tttgatacca tggctgttaa
     2761 attgtctcaa aaaggggttc aatttgctgc caatggtagt caggttaagt ttgatggtta
     2821 tcttgccatt tataatgatt ctgacaagaa taagatgtta ccggacatgg ttgttggaga
     2881 tgtggtcaaa caggtcaata gcaaaccaga gcaacatttc acccaaccgc ctgcccgtta
     2941 ttctgaagca acactgatta aaaccttaga ggaaaatggg gttggacgtc catcaaccta
     3001 cgcgccaacc attgaaacca ttcagaaacg ttattatgtt cgcctggcag ccaaacgttt
     3061 tgaaccgaca gagttgggag aaattgtcaa taagctcatc gttgaatatt tcccagatat
     3121 cgtaaacgtg accttcacag ctgaaatgga aggtaaactg gatgatgtcg aagttggaaa
     3181 agagcagtgg cgacgggtca ttgatgcctt ttacaaacca ttctctaaag aagttgccaa
     3241 ggctgaagaa gaaatggaaa aaatccagat taaggatgaa ccagctggat ttgactgtga
     3301 agtgtgtggc agtccaatgg tcattaaact tggtcgtttt ggtaaattct acgcttgtag
     3361 caatttccca gattgccgtc atacccaagc aatcgtgaaa gagattggtg ttgagtgtcc
     3421 aagctgtcat cagggacaaa ttattgagcg aaaaaccaag cgtaatcgcc tcttctatgg
     3481 ttgcaatcgc tatccagaat gtgaatttac ctcttgggac aagcctgttg gtcgtgactg
     3541 tccaaaatgt ggcaacttcc tcatggagaa aaaagtccgt ggtggtggca agcaggttgt
     3601 ttgtagcaaa ggcgactacg aggaagaaaa tattaaataa gaggaggggc ccgaaagtaa
     3661 atttcaggct ccttttggtt agaacttgac aaaatacatc attttatgcg aaactagaag
     3721 aagattattt taactaggag aagttatgcg tcttatctat ctgataattg gttttttatc
     3781 actggccttg gctattgttg gggttgtttt acccttgttg ccgacaacgc ctttcctttt
     3841 gttgtctatt gcttgtttct ccagaagttc caagcgtttc gaagactggc tttatcatac
     3901 caagctctat caaacatatg tagctgattt tcgcgagact aagtctatta cgcgtgaacg
     3961 aaagaaaaaa atcatcgtct ctatctacgt cttgatggga atttctattt attttgcacc
     4021 tcttttacca gtcaaaatcg gtctgggtgc tttgaccatc tttatcacct attatctctt
     4081 caaggtcatt ccagacaaag aataattaaa acagtagtta tttcccttga taaaattgaa
     4141 agcatattca taacaatatg atataataaa tttgaagtaa tattcaagga gaatcaaatg
     4201 atttacgaat tttgtgctga aaatgtgacc ttgcttgaaa aagcgatgca ggctggagct
     4261 cgtcggattg aactctgtga taatctagca gttggtggga caacccccag ctatggagtg
     4321 actaaggcag cggttgaact ggcagctaac tacgatacaa ccatcatgac catgattcgg
     4381 ccacgtggtg gtgactttgt ctataatgac ctagaaattg ctatcatgct agaagacatt
     4441 cgtttgactg ctcaggctgg aagtcaaggg gttgtatttg gagttttaac tgctgataaa
     4501 aagttggata agcctaatct ggaaaagtta attgctgcat caaaaggaat ggaaattgtc
     4561 tttcacatgg cctttgatga actaagtgat gaagatcaac cggaagctat tgactggctc
     4621 agtcaagtcg gtgtcactcg tatcctaact cgtgctggtg tgtctggcga ctccttagaa
     4681 aaacgttttg ttcactatca cagaattttg gagtacgcta aaggtaaaat tgaaattcta
     4741 ccaggtgggg ggattgacct tgacaaccgt caaaccttta tcgaccaggt gggggtaaca
     4801 cagttgcatg gtactaaggt tgttttttaa aaaatagaaa ggaactgcta gctttgggta
     4861 gcagttttca cttatgtttg aaatttttaa atcctatcaa tttaatcaag aaaaggctca
     4921 tgattatggt tttatagaaa atagcgaagt ctggacatat agttgccaga ttttgcaagg
     4981 tgactttgtc atgactgtgt ccatcactgc tgataatgtg aactttcaag tctttgacca
     5041 agagactggc gacctctatc ctcacgttta tatggaaagc atgaggggaa gttttgtcgg
     5101 aaatgtccgt gaggcttgtc tggagattct ttaccagatt cggaaggctt gttttgatgt
     5161 gcaagatttt atctgtcatc agactaagcg tatcatgact caagttcagg aaaagtatgg
     5221 aaaccagttg gagtatctgt gggaaaaatc gcctgataca gctgtattgc gccatgaagg
     5281 caatcaaaag tggtatgccg tcttgatgaa aatctcttgg aataagctgg aaaagggcag
     5341 agaaggacaa gtggaagcag tcaacctcaa gcatgaccaa gtagctaatt tactttcaca
     5401 aaaggggatt tatccagcct ttcatatgag caagcgctac tggattagtg tgtcccttga
     5461 tgatacttta tcagatgaag aagtactgga attgatagaa aaaagttgga acttaacctc
     5521 taaaaaatga aatattttaa taattttcat gaactttcaa ttagctaaat attctttact
     5581 gaagaaattt tcagaaaata taggatttac cacactagag gaatatggtg catcttcaaa
     5641 tacctgattg agaatgtcaa gacggatcgt cagatcatct attcgcctca ctgtcatgat
     5701 gacctcggaa tggcagtggc aaatagcctt gctgctgtca agaatggtgc aggacgtgtt
     5761 gaagggacta tcaatggtat tagggagcga gctggaaatg ctgctttgga agaaattgca
     5821 gtggctctca atattcgcca agattactac caagtagaaa ccagtattgt cctaaatgag
     5881 accatcaata cgtcagaaat ggtttctcgc ttctctggta ttccagttcc taaaaacaaa
     5941 gccgtcgttg gtggcaatac cttctcccac gaatctggta ttcaccaaga tggagtcctt
     6001 aaaaatcctc tcacttatga gatcatcaca cctgaattgg ttggtgttaa gattccgctt
     6061 gggtcgccat gcttttgttg agaaactgag agaattggcc ctagatttta cagaagagga
     6121 tatcaaacca ctctttgcta agttcaaggc actggccgat aagaagtaag aaatcacaga
     6181 tgcagatatt cgagctttgg tagctggaag catggttgaa aatccagaag gcttccactt
     6241 tgatgattta caacttcaaa ctcatgcaga taatgacatt gaagcgctcg ttagcctagc
     6301 caatatggat ggtgagaaag tcgaatttaa tgcgacaggg caaggttccg ttgaagcaat
     6361 ctttaatgct atcgataagt tctttaacca atctgttcgt ttggtgtcct acactatcga
     6421 tgcggtaaca gatggaatcg atacccagga tcgggttttg gtcactgttg aaaacagaga
     6481 tacagaaacc atctttaatg cagcagggct tgattttgat gtgttgaagg cttctgctat
     6541 tgtctatata aacgctaata cctttgttca aaaagagaat gcaggtgaga tgggacgcag
     6601 tgtttcttac cacgatatgc ctagtgtgta aaggagaagg ctatggcaaa gaaaatagta
     6661 gctctagtag gagacggaat tggcccagaa atcatggagg ttggtttaga agttctggag
     6721 gctctagctg aaaaaacagg ttttgactat gagattgaca gacgaccgtt cggaggtgca
     6781 gatattgatg cagcatggcc tcccttacct gatgaaaccc ttaaggcaag tagggaagca
     6841 gatgctatcc tactagcaac tatcggtagt cctcagtatg atggagcagt ggttcgccct
     6901 gaacaaggcc tgatgactct ccgtaaggaa cttaatcttt acgctaatat tcgtcctgta
     6961 aaaatctttg acagtctcaa gcatttgtca ccactcaaac tggaacgaat tgctggtgta
     7021 gactttgtcg tggtgcgtga attgacaggc gggatttact ttggagatca tattcttgaa
     7081 gagcgcaatg cgcgtgatat caacgactat agctatgagg aagtggagcg gattattcgc
     7141 aaagcctttg aaattgcaag aaatcgcaga aaaatcctta ctagtatcga taagcaaaat
     7201 gttctagcga cctcaaaact ctggcggaaa gtagctgagg aagtcgcaca ggatttctca
     7261 gatgtaacct tggaacacca gctggtagac tcagctgcta tgcttatgat taccaatcct
     7321 gctaagtttg atgttattgt aacggagaat ctttttggag atattttatc tgatgaatca
     7381 agcgtcttat ctggtacact tggggttatg ccatcagcca gtcattctga aaatggacca
     7441 agtctctatg aacctattca cggttcagta cctgatattg caggtcaagg aattgccaat
     7501 cctatttcca tgattttatc agtttccatg atgttaagag atagtttcgg aggttatgag
     7561 gatgcagagc gtatcaaacg tgctgttgag acaagtttgg cggcaggaat tttaacgaga
     7621 gatataggag gtcaggcttc aacaaaggaa atgacggaag ctattattgc aaggttatga
     7681 agttagacga aaaaattact ctagtccttt tgatttggaa tgtcatcatt ttcttgattt
     7741 atggcattga caaattcaag gcaagaagaa gagcttggcg catcccagag aaaatcttac
     7801 tcattttagc ccttacttgt ggtggttttg gggcctggtt agctggaatc acttttcacc
     7861 acaagactcg aaaatggtac tttaaaacag tttggtttct tgggatggtg accacactag
     7921 tagccttata ttttatttgg aggtaatgga tggcagggtc ttcgagggaa cacgctgctt
     7981 gggctctagc ggactatggt tttaaggtcg tgattgcagg atctttcggt gacattcatt
     8041 acaataatga actcaataat ggcatgttgc caatcgttca gcctagagag gttagagaga
     8101 aactagccca gctaaaacca accgaccagg taactgtgga cttggaacaa caaaaaatca
     8161 tctcaccagt tgaagaattc accttcgaga tagatagcga gtggaaacat aaactcctaa
     8221 atagtttgga tgatatcggt attaccttgc agtatgaaga gttgattgct gcttatgaaa
     8281 aacaacgacc agcctactgg caggattaga aaaaatagaa aaggaaatat agtaaactga
     8341 aataagatgt aaacaaatga attggagctt aacatccatt tccagcaatt ttttagaaac
     8401 tacagtggac tattctggat tcaacacatt ataaaattat gacaaaacac attcacaaga
     8461 aggctacgac attttaaaag gtgagggcgg atgtatcgtt tgccctacta aagttggtta
     8521 cattatcatg accagcgaca aggcaggact tgagcgtaag tttgcagcca aagaaggtaa
     8581 gcgtaacaaa ccaggtgttg ttctctgcgg tagcatggat gaactttgcg ctttagcgca
     8641 actcaaccca aaaattgaag cattctacta aaaacattgg gatgaagata ttcttcttgg
     8701 ttgtatcctt ccttggaaac cagaagcctt tgaaaaactc aaagcatacg gggatggccg
     8761 tgaagaactt atgactgatg tacgtggtac tagctgtttt gttatcaagt ttggaaaagc
     8821 aggtgaacaa ttggctgcca agctttggga agaaggtaaa atggtctacg cctcatatgc
     8881 ttcaatgaca aaacgattga aactcgctat gagagcaagg tgtaatggtg tctatggtcg
     8941 ataaggacgg caaactcatc ccagaacaag gaggagcacg ttcaacctca ccagcaccag
     9001 ttgtgatccg taaagggctt gacattgata aaatcatgat gcacctgtca gacaccttta
     9061 acttatggga ctaccgtcag gttgagtatt attaggatag agaagaagtc tagtgttaag
     9121 gacattacag ctcataatac taggcttttt tatagaaatt cttttctttt tctataggat
     9181 atggtattct atgtagaaaa tatatgttaa taagtaatgc caatatttaa acatcattag
     9241 taaaaggagt tagattgatg aataaaagaa aagttagttt agaagatttt tataaatggt
     9301 atagtctaaa taaagaagag ttattaaata aggcaactgt tggtgaaaag tttaatgata
     9361 aattaaaaga agagtttctc caggaatggc ctttggatag gattttaaca atgtcaatcg
     9421 atgaatatgt aataggaaag ggacagcaaa ataagtcttt atgctacgct cttgagaagg
     9481 gaaaatacaa aaatctattt cttggaattt ctggtggctc agcttcaaaa tttggtattt
     9541 attggaataa aaaaacaaac aaatataaag atcaagctaa taatgagatt tcagagttgg
     9601 atcagcgatt ttcaaaatta aaatcagatt tgtatgaaat tatcaaagaa ggtattcgtt
     9661 ttaactttga aaatcctatt tttgatatga aaagatcaac aaatgaattt attggtcgtt
     9721 ctgctatggt gacaaaatta ctttgtatct attctgaggg agattctttc tttggtgtaa
     9781 atattaatag tcagaaagaa ttttggaacc actttgtttc tcagacaaat caaggtggac
     9841 cttatctgca aaatcataaa ataattgaac tggtgccaaa acttatcctg agttggagcc
     9901 atcgaaatta ggaactatgc tttttgagta ttctaagctt tttatggaaa ataaggaaga
     9961 caatagtaca atggattcat caaacaattt tcgtcatcaa ttaactcaat ctctattaaa
    10021 gtctccaaac cttatccttc gtggtgctcc tggcacagga aagacttatc ttgctaaaga
    10081 aattgccaaa gaattaacgg atggcaacga agaccaaatc ggatttgtac aatttcaccc
    10141 atcatatgat tatacggatt ttgtagaagg tttaagacca gtatcaaatg gggatggagc
    10201 tattgagttt aggctacagg acggtatttt taaagatttt tgtcagaaag caaaagaaac
    10261 ccaattgatt ggaggacaag ataattttga tgaggcttgg gattcttact tagaatatat
    10321 aaatgttgct gaagaaaaag aatatataac aaaaacatct tacttatctg ttaatagtag
    10381 acaaaatttg tcagtaaatt atgatagtgg tgttccagga tggtcactac ctagcaaata
    10441 tgtttacgag ttgtataaag ataaaaatta taataagcaa gaatactaca aaagtggtgg
    10501 aaaaactgtc ctagaaacat tgagaaagag atttggtttg aaagactatg tttccccaac
    10561 agaaattgat actgataaga aattcgtctt catcatcgat gaaatcaatc gtggggagat
    10621 ttctaagatt tttggcgaac tctttttctc tatcgaccct ggctatcgtg gtgaaaaagg
    10681 aagtgtttct acccaatatg caaatctaca cgaaactgat gaaaagttct atatccccga
    10741 aaatgtttac atcatcggaa ctatgaatga tattgatcgt tcagtggata cctttgattt
    10801 tgctatgcgt cgtcgttttc gttttgttga agttactgcc gagggtcaag ttggcatgtt
    10861 ggataaagag ctgaatatcc atgcagaaga agcaaaaatt cgtctaagaa acttgaacgc
    10921 tgctatcgaa aatgttcagg aattaaacag tcattatcat attggaccaa gttattttct
    10981 taagttgaag gatgtagatt ttgactatga attactctgg tccgattata ttaagcctct
    11041 cctagaagac tacttgcgag gttcttatga tgaggttgaa actttggaaa ctttgaaaaa
    11101 agcatttgaa ctgacaaata atgagcaaaa agatcaggca gtagctgatg acaatgaagg
    11161 tgatgaaaac gatgatgcgg attactgata atcaacacaa gattattaaa gaaaaatttg
    11221 ttgaagaata tcctaaacta agcaatcttc ttttagacag aaccttggaa agtctatccc
    11281 aagatgaacg tattttcatt tttccaaatg atttgactca tactcctgat ttggataagg
    11341 accaaaagat ttttgaaaca gtcaatcaga aaatcaagac agggaacgtg attggttttc
    11401 ttggatatgg tcaggaaaga ttaacgattt cctcacgatt ttctgatgag agtaatgacc
    11461 attttttgca ttatctctta aacaaggttc ttcatatcaa tctcactagt ttagatgttg
    11521 ctttgtctcg tgaagagagg ctttatcaac ttttggtgta tctctttccc aagtatctac
    11581 aagctgctat tcgaaaaggt ctttataagg aatatcatcg attttctcat aacgacagta
    11641 atgttaaggg agtgattgat gtaagaagcc atctcaagaa aaatcttcct ttcacgggaa
    11701 atattgccta cgcaacgaga gagttcacct atgataatcc cctcatgcag ttggtccgtc
    11761 acactattga atacattaag aatcagaaaa gcattggtca aggggtacta gataatctct
    11821 caactagtcg tgaaaacgta tctgaaatcg tgcgtgtaac gccctcttat aaactagctg
    11881 atcgtgctaa gattattcgg ggaaatcaat ctaaacctat acgtcatgca tactttcacg
    11941 agtacagaaa cttacaagaa ctttgtctga tgatcctaaa ccaagaaaag cacggtttag
    12001 ggtatcaaga tcaaaaaatc tatggtattc tctttgatgt tgcctggctt tgggaagagt
    12061 atgtttacac cttgttgcca aaaggttttg tacatcccag aaataaggat aagacggatg
    12121 gaatttcagt attttctgtt gggaaacgaa aagtatatcc agatttttat gacagagaac
    12181 gaaagattgt tctagatgca aaatataaaa aactggaatt gactgaaaaa ggaatcaacc
    12241 gtgaggactt attccagctg atttcctatt cttatatttt aaaagctgag aaggctggac
    12301 tgatttttcc tagtatggag cagtcagtaa atagtgaaat aggaaaagta gctggctatg
    12361 gagctcaatt gaagaagtgg tctattcgaa tccctcagaa tgcctcattc tatagtacat
    12421 tttgtaaaat gatggaaaat tcagaagaaa attttaaagc gattattgat gaagaagtgg
    12481 ggagaaaata atttcccctc tttcttttat ttttaacaca agtaaaaccc gaacgatata
    12541 ttttaattca taaaataatt tgacaaaaac tgtactttgg tttataataa attaaggaaa
    12601 cgtcggaaaa ggcgtagtga tgcaagagca taggtaggtc attacaaaag aaacgagaca
    12661 tcgatatgtt aaatgaattt ccaatttttg attacgaaga tattcaattg attccaaata
    12721 aatgtgtcat taaaagccgt gcagaagcgg atacaagtgt cactttagga aatcacacct
    12781 ttaaactacc tgttgtgcca gcgaatatgc agacgatttt ggatgaaaat gtagcagagc
    12841 aactggctaa aggtggttac ttctacatta tgcaccgttt tgatgaggca ggacgcattc
    12901 cttttattaa acgaatgcac gatcaagggc tcattgcttc tatctctgtc ggtgttaagg
    12961 attatgagta tgatttcgtt agacagctca aggctgatgc tcctgagtat atcactattg
    13021 atattgctca tggtcatgcg gatagcgtga tttctatgat tcaacacatc aagaaagaat
    13081 tgccagatac ctttgtcatt gctggaaatg tgggaacacc agaagctgtg cgtgaattgg
    13141 aaaatgctgg tgcggatgct actaaggtcg gaatcggtcc tggtaaggtt tgtatcacca
    13201 aggttaagac tggttttggt acaggtggtt ggcagttggc tgctctacgc tggtgtgcca
    13261 aggctgcgcg taaaccgatt atcgctgatg gaggaattcg tactcacggt gatattgcta
    13321 agtctatccg cttcggtgct agcatgatca tgattggttc cctctttgca ggacacattg
    13381 aaagtccagg gaaaacgatt gaagtcgatg gtgaacagtt caaagaatat tatggttcag
    13441 cctcacaata tcaaaaaggt gcttacaaaa atgtggaagg caaacgtatc ttgcttcctg
    13501 ctaaaggtca tctgcaagac actttaactg agatggaaca agaccttcaa agtgctattt
    13561 cttatgcagg tggacgtcag gttgctgacc ttaaacacgt tgattatgtg atcgtgaaaa
    13621 actccatctg gaatggggat gcttcccact aagacggggt ctttgaccaa aaaacttgtt
    13681 attagagcaa atttctgtta taataaaaca agtttccacc cttagtgtaa tggatatcac
    13741 gtaagattcc ggttcttgag atgggggttc gattccctca gggtggatgt aaacatccta
    13801 aaaagccttt aatagggctt ttttctttat cctgacccaa atttgccgct aaaactgaga
    13861 atctctgtct aaagaattcc caaatgcttt ccagtcccgt tttagagtga ctcagggggc
    13921 tttttttgat ataataaaaa ggactattat cagttagaaa gaggttggta tgaaagaatt
    13981 acaaactgta ctaaagaatc attttgcaat cgaatttgca gacaaaaatt tactggaaac
    14041 tgcctttact catacgagtt atgccaatga gcaccgcctc ttaaaaattt cacacaatga
    14101 acgcttggaa tttttaggag acgctgttct acagttattg atttcagaat atctatataa
    14161 aaaatatcct aaaaagcctg aaggtgacct atcaaaactc cgtgctatga ttgtccgtga
    14221 ggagagttta gctggttttg cgcgtgattg ccagtttaac cagtttatca agttgggtaa
    14281 aggggaagaa aaatcaggtg gtcgcaatcg tgacaccatt cttggtgatg cctttgaagc
    14341 ctttcttggt gcccttcttt tggataagga tgtggccaag gtcaaggaat ttatctatca
    14401 agtcatcatt cctaaggttg aagcaggcga gtttgagatg attacagact ataaaaccca
    14461 tctccaagag ttgcttcagg tcaatggtga tgtggctatt cgttatcagg tgatttctga
    14521 aacagggcct gctcatgata aggtctttga tgtagaagtt cttgttgaag gtaagagcat
    14581 cggtcaaggc caaggtcgtt ctaagaaatt agcagagcag gaagctgcca aaaatgccgt
    14641 tgagaagggg ctggattcat gtatttaaag gaaatcgaaa ttcaggggtt caagtctttt
    14701 gctgataaga ccaaggtcgt ttttgaccaa ggtgtgacgg cagttgttgg acccaatgga
    14761 tctggaaagt ccaatattac agaaagtctg cgttgggctt tgggggagtc tagtgtcaag
    14821 agtctccgtg ggggcaagat gccggatgtc atctttgctg gaaccgaaag tcgcaaaccg
    14881 ctcaattatg cttctgtagt tgtgactctg gataatcatg acggatttat caaggatgca
    14941 ggtcaagaaa tcagggtgga acgccatatc tatcgtagtg gagatagcga atacaagatt
    15001 gacggcaaga aagtccgtct gcgtgatatt catgacctct tcttggatac tggattggga
    15061 cgagattcct tctctattat ttcccaaggg aaggttgagg agatttttaa ttccaagcct
    15121 gaggaacgac gagctatttt tgaagaagct gctggagttt taaaatacaa gactcgcaga
    15181 aaagaaaccg agagtaaact gcagcaaact caggataatc tggaccgctt agaggacatt
    15241 atctacgagt tggataatca aatcaagcct cttgaaaagc aagctgagaa tgcccgtaag
    15301 tttttagact tggaaggaca acgtaaggct atttatttag atgttctggt tgctcaaatc
    15361 aaggaaaata aggctgaact agagtcgaca gaagaagagt tggctcaggt tcaagaactc
    15421 ttgatgagtt attaccaaaa gcgtgaaaaa ttagaagaag aaaatcaaac tcttaaaaag
    15481 caacgccaag atttacaggc tgaaatggcc aaagaccaag gcagtttgat ggatttgacc
    15541 agtctgatta gtgacttaga gagaaaatta gccctatcga aactggaatc tgagcaagta
    15601 gccctcaatc aacaggaagc acaagcccgt ttggctactt tggaggataa gagaagttca
    15661 ctcagccaag aaaaatctga taaagaaagc tctttagccc tcttggaaga aaatctagtc
    15721 caaaataatc aaaaactcaa tcgattagag gctgaattgc tagctttttc agatgatcct
    15781 gatcagatga ttgagctctt acgtgaacgc tttgtggccc ttttacaaga agaagcagat
    15841 gtctcaaacc aactgacccg tattgagaat gagttggaaa atagtcgtca gctttctcaa
    15901 aaacaagcag atcaactaga aaagctgaaa gaacagttgg ctacagctaa agagaaggct
    15961 ggtcagcaaa aggctgagct tgaaactgcc aaggagcagg ttcagaaatt attggccgac
    16021 tatcaagtct gtgctaagga gcaagaggag cagaaaactt cctatcaagc tcaacaaagt
    16081 caactctttg accgtctgga tagtctcaaa aacaagcagg ctagagcgca aagtttggaa
    16141 attatcctga gaaatcatag taacttttat gcaggtgtta agagtgttct ccaagagaaa
    16201 gatcgtctag gtgggattat tggagcagtt agtgagcacc tgacctttga tgtgcattat
    16261 caaactgccc tagagattgc gcttggagcg agtagccaac atatcatcgt ggaagatgaa
    16321 gagtcggcaa ccaaggcgat tgatttactc aaacgaaaca gatctggtcg tgcaaccttc
    16381 cttcctttga ccactatcaa ggctcgtacg atttctagtc agaaccaaga tactattgct
    16441 gcaagtccag gatttctggg catggcagat gagctggtta ctttcgatac tagactggaa
    16501 gccattttca agaatttgct agctacaacg gccatttttg ataccgtgga gcatgcgcgt
    16561 gcagcagcgc gccaggttcg ttatcaggtt cgtatggtga cattggacgg aacagagctg
    16621 cgcacaggtg gttcttatgc aggtggagct aatcgccaga ataacagtat tttcatcaag
    16681 ccagaactgg agcaattaca aaaagaaatt gctgaagaag aagcaagttt gcgttcagat
    16741 gaagtgagtt tgaagaactt gcaagatgag ctagctagat tgacagaaag attagaagcc
    16801 atcaaatctc agggagagca ggctcgtatt caggagcaag gcttgtccct cgcctatcag
    16861 cagaccagtc agcaagttga agagctagaa actctttgga aactccaaga agaggaatta
    16921 aatcgtcttt ctgagggaga atggcaagcg gataaggaaa aatgccaaga gcgccttact
    16981 acaatcacta gtgaaaagaa taatctggaa gctgagattg aagagattaa gtctaataaa
    17041 aacgccatcc aagaacgtta tcaaaacttg caggaagagc tagctcaagc tcgtctactt
    17101 aagacagaac tgcaagggca aaaacgttat gaagttgctg atattgaacg cttaggtaag
    17161 gaactagata atcttgatat tgagcaagaa gaaattcagc gccttcttca agaaaaggtt
    17221 gacaatcttg agaaagttga tacggatttg ctcagtcaac aggctgatga agccaaaact
    17281 caaaaaacaa atctccaaca aggtttgatt cgcaagcagt ttgagttgga tgatattgag
    17341 ggtcaactgg atgatattgc tagtcatttg gatcaggctc gccagcagaa tgaagagtgg
    17401 attcgcaagc aaactcgtgc tgaagccaag aaagaaaagg ttagcgagcg cttgcgccat
    17461 ctacaaagtc aattaacaga ccagtaccag atcagctaca cagaagcttt agaaaaggcg
    17521 catgagttgg aaaatctcaa tctggcagag caagaagtta aggatttaga gaaggctata
    17581 cgctcactgg gtcctgtcaa tttagacgct attgaacagt acgaagaagt tcacaaccgt
    17641 ctggatttcc taaatagcca acgtgatgat attttgtctg cgaaaaacct gctccttgag
    17701 accattacag agatgaatga tgaggtcaag gaacgcttta aatcaacctt tgaggtcatt
    17761 cgtgagtcct ttaaagtgac cttcaagcag atgtttggtg gaggtcaggc tgacctcatt
    17821 ttgactgaag gagacttgct gacagctggg gttgaaattt ctgtccaacc accaggcaag
    17881 aaaatccagt ctcttaatct catgagtggt ggtgaaaaag ccctatcggc tcttgccttg
    17941 ctcttctcca ttattcgtgt caagactatt ccatttgtta tcttggatga ggtggaagct
    18001 gcgctggatg aagccaatgt taaacgtttt ggggattacc tcaaccgctt tgacaaggac
    18061 agccagttca tcgtcgtaac ccaccgtaag ggaaccatgg cagcggctga ttccatctat
    18121 ggagtgacca tgcaagaatc gggtgtttca aagattgttt cagttaagtt aaaagattta
    18181 gaaagtattg aaggatgaca attaaactag tagcaacgga tatggacgga accttcctag
    18241 atgggaatgg acgctttgat atggatcgtc tcaagtctct cttggtttcc tacaaggaaa
    18301 aagggattta ctttgcggta gcttcgggtc ggggatttct gtctctagaa aaattatttg
    18361 ctggtgttcg tgatgacatt attttcatcg cggaaaatgg cagtttggta gagtatcaag
    18421 gtcaggactt gtatgaagcg actatgtctc gtgactttta tctggcaact tttgaaaagc
    18481 tgaaaacttc accttatgta gatatcaata aactgctctt gacgggtaag aagggttcat
    18541 atgttctaga tacggttgat gagacctatt tgaaagtgag tcagcactat aatgaaaata
    18601 tccaaaaagt agcgagtttg gaagatatca cagatgacat tttcaaattt acaaccaact
    18661 tcacagaaga aacgctggaa gatggggagg cttgggtaaa cgaaaacgtt cctggtgtta
    18721 aggccatgac aactggcttt gaatccattg atattgttct ggactatgtc gataagggag
    18781 tggccattgt tgaattagtt aaaaaacttg gtatcacaat ggatcaggtc atggcttttg
    18841 gagacaatct taatgactta catatgatgc aggttgtggg acatcctgta gctcctgaaa
    18901 atgcacgacc tgaaatttta gaattagcaa agactgtgat tggtcaccat aaggaacggt
    18961 cggttatagc ttatatggag ggcttataat ggcagatata aaattgattg cattggactt
    19021 ggacgggacc ttgctgacta ctgataaaag gctgacggat cgtaccaagg aaaccttgca
    19081 agctgcgcgt gatcgtggta tcaaggtcgt attgacaact ggtcgtccct taaaagccat
    19141 ggatttcttt ctccatgagt tagggactga cggtcaggaa gatgagtata ccattacttt
    19201 taatggtgga ttagttcaga aaaatacagg agaaatcctt gataaaacag tcttttcata
    19261 tgatgatgtg gcacgtttgt atgaagaaac agagaaatta tcactgcctc ttgatgccat
    19321 ctcagaagga acagtttatc aaatccaatc ggaccaagaa agtctttatg ccaaattcaa
    19381 tccagctttg acctttgttc cagtggactt tgaagactta tctagtcaaa tgacctacaa
    19441 caaatgcgtg actgcctttg ctcaagaacc cttggatgca gccattcaga agatttctcc
    19501 agaattgttt gaccaatatg aaatctttaa atcacgtgaa atgttgctag aatggtcacc
    19561 aaagaatgtt cataaagcaa caggtttggc aaaactaatc agccatcttg gaatcgacca
    19621 aagtcaagtg atggcttgtg gtgacgaggc caatgacctc tctatgattg aatgggcagg
    19681 tcttggtgtt gctatgcaaa acgctgttcc tgaagtaaag gcagccgcaa atgtagtgac
    19741 gccgatgacc aacgatgagg aagctgtcgc ctgggctatc gaagaatatg tgctaaagga
    19801 gaactaagat atgggattgt ttgaccgtct attcggaaaa aaagaagaac ctaaaatcga
    19861 agaagttgta aaagaagctc tggaaaatct tgatttgtct gaagatgttg atcctacctt
    19921 cacagaagtt gaggaagttt ctcaggaaga agcagaggtt gaaattgttg aacaagctgt
    19981 gttccaagaa gaggaaatcc aagacacagt tgaagaaagt caggattcag agccagctgt
    20041 aggggtttct caagaagaaa tagaagaatt accaaactca gaagaattac cagaggaaga
    20101 gaagcttgag cacgaaggaa ctgtagaaga aaataattct gaagtgcttg aaccagaagc
    20161 tcctcaaaca gaagaaactg ttcaggaaaa atatgaccgc agtcttaaga aaactcgcac
    20221 aggtttcggt gcccgcttga atgccttctt tgctaacttc cgctctgttg acgaagaatt
    20281 tttcgaggaa ctggaagaac tgctgattat gagtgatgtt ggtgtccaag tcgcttctaa
    20341 cttaacggag gaactacgtt acgaagccaa gcttgaaaat gccaagaaac ctgatgtact
    20401 tcgtcgtgtc atcattgaga aattggttga gctttatgaa aaggatggta gctacgatga
    20461 aagcatccac ttccaagata acttgacagt tatgctcttt gttggtgtga atggtgttgg
    20521 gaaaacaact tctatcggaa aactagccca ccgctacaaa caagctggta agaaggtcat
    20581 gctggttgca gcagatacct tccgtgcggg tgcagtagct cagctagctg aatggggccg
    20641 acgagtagat gttccagtag taactggacc tgaaaaagct gatccagcca gcgtggtctt
    20701 tgatggtatg gaacgtgccg tgactgaagg tatcgatatt ctcatgattg atactgctgg
    20761 tcgtctgcaa aataaggata accttatggc tgagttggaa aagattggtc gtattatcaa
    20821 acgtgttgtg ccagaagcac cacatgaaac cttcttggca cttgatgcat caacaggtca
    20881 aaatgcccta gtacaggcca aagaattttc gaaaatcaca cctttaacgg gaattgtttt
    20941 gactaagatt gatggaactg ctcgaggagg tgtggttcta gccattcgtg aagaactcaa
    21001 tattcctgta aaattgattg gttttggtga aaaaatcgat gatattggag agtttaactc
    21061 agaaaacttt atgaaaggtc tcttggaagg tttaatctaa tcagaagcaa aaatcctgca
    21121 aggcataaac ttgcaggaaa tttttttatt ctaagcgacc atcttgacga taggtgatat
    21181 ctggttgcca agtccatttg gcaccgaatt tttcaagtag gtcaaagctg gcttgaggtc
    21241 ccatgcttcc agctttatag tcatgaagtg gggcaccatt ttcagcccag agcttttcaa
    21301 tacggtcaat caacttccat gacgcacaaa cttcatccca gtggctaaag ttagttgagt
    21361 tgttatttag gacatcataa atcaattttt cgtatggttc tggagaagca ccagttgcag
    21421 tcgcatctgt acggtaatca agtgagttag gagccaagtt aaattcttct cctacttgct
    21481 tcccatttag gctaagagag aagccttctg ttggttgaat atagatggtc aaaatatttg
    21541 gagcaagtgg ttctccaaag atagaatcca tttgtttaaa gacgatgttg acatgggttc
    21601 ctttttcagt cagtcgttta cctgtacgga aaaagaaagg aacaccacgg aatcgatcgc
    21661 tgtctacaaa gaaggcacca gatgtaaagg tttcagttgt tgattctgga ttcacatttg
    21721 gctcgctacg ataagagatg tatttcatgc catcaatctt accagagcgg tattgcccac
    21781 ggataaagtg ttctttgagt tcttcatcag ttggatgata gaggttttta aagaccttaa
    21841 tcttttcagc acgaatctcg tcttttgtga agcttgctgg tttgtccatg gcgaggagcg
    21901 aaagaagttg tagagtgtgg ttttggacca tgtcacggag ggcaccggat tggtcatagt
    21961 agccaccacg ttcttctaca cccaagcgct ccgcaaaggt aatttgaaca ttgtcgataa
    22021 aatccttgtt ccaaacgttt tcaaaaatca agtttgcaaa gcgaactgca aagatgcttt
    22081 ggatcatttc cttaccaaga taatggtcga tacggaaaat ttgttcttcg tcaaatgttg
    22141 ctaggagttc gtcattcaac ttgcttgcag ttgcgtaatc tgtaccaaat ggtttttcaa
    22201 cgatcaagcg ctcaaaacct ttgccatcga caatgttttc agatttgagg tgtttggcaa
    22261 tggttccaaa gaactgaggt gccatagaca agaagaagag cttattgtgt tcagcttggt
    22321 atttttcatt aagctcagct tgtaattgac gcaaagcaat ataatgttcc gaatcattga
    22381 catcatggct ttgatagtag aagtggctag caaattcttg ggcttgctcg gtactatctg
    22441 ccaaatcaag gatggactcg acaactacag attcaaaata ttccttactc caaggtctac
    22501 gggcagttcc aataacggca aagtgcttgg aaagattgcc ggattgatat agtctaaaaa
    22561 gggaagggta gagcttgcgt ttagccaggt ctccactcgc accgaaaatt gtaacaataa
    22621 ccttagatga catctagcta cctaatttct atttttattc ctagtcttgc taggtatgag
    22681 gaaacctcat ttcataaact taattctaac ataattttcc gaaaaatcaa aaattccaat
    22741 acgaggtaga aaaactgcaa ggaaatcctt acagtttgag tttagacgtt taagacctta
    22801 tctaagaact ctttcagacg agggtgttgt gggttatcaa agatttggtc aggtgttccg
    22861 tcttcaagga actcgccatc tgcagtaaag ataacgcggt tggcaacctg acgagcaaat
    22921 cccatctcat gggttacgat aatcatggtc atgccttgct cagccaattc cttcataacg
    22981 ttaagtacgt ctccaaccat ctcagggtca agggcagaag ttggttcatc gaagagcatg
    23041 atgtctggat tcattgctag gccacgagcg atggccacac gttgtttttg accacctgat
    23101 aggctatctg gattggcatt agctttatct gctagtccaa ccttttcaag caactccatt
    23161 cccaattcct cagcttcttc cttagtcatc aacttgtgct caataggagc aaaggtgatg
    23221 ttgtccaata cagacatatg agggaagagg ttgaagtgtt ggaataccat gccgatattt
    23281 tcacggacgt ggtcaacatt ggttgttttt tcagttaaat catagccgtt cacagtgatg
    23341 tgaccgctag tgacttcttc taaaagattg aggctacgga ggaaagttga cttaccagaa
    23401 cctgaaggac cgatgataca aacaacatct ccttcataga acttagtcgt aattcctttt
    23461 aggacttcat tttttccata gtgcttgtgt aaatcattta catcaatttt taattttacc
    23521 attaacgaat cctcttttct aagcgtttcg ctagtctagt caaaagtgtg ataattacaa
    23581 gatagaagat agcaaggatt gcatacatct tgaaactttg gtagttacga gcaatgataa
    23641 tcttaccagt ttggaagagt tcaaccaaac cgatagcaga tacgatagtt gtatctttaa
    23701 gagcgataac gaattggttg acaaagtttg gcaacatcaa tttagttgct tgtggcaaga
    23761 taatcttacg catggttttt ccataagaga tacccaagct tcggctggct tccatttggc
    23821 caactggaac ggcctgaata ccaccacgaa cgatttcagc gatataagca gccgcattga
    23881 gtgagagggc aatggttcca gctacaaagt cgttaattgg gctttgttgg cctgtgatag
    23941 actcgatgaa gtttggaatt ccccagaaga tgaaggctgc aagaatcatc aatggaatac
    24001 cacgaataac gtcaacgaaa atctcagaga tgacgcgaag agatttgtat gggctaacgc
    24061 taaacatacc gaagataatt ccgatgacaa tggcaatagc aaatgagata agagctagag
    24121 caagagtgat accaagaccg ctaaggagtt gtttgtagtt gttttgaagc aagccccaga
    24181 gcgttgtttc gtcaacagta cttgttgaag cagttgaaga ttcgctagct aggtatttgt
    24241 caagaatctt ttggaattca ccgtttgctt taaggtttgc aagtccgttg ttgaacattt
    24301 caatcagttc tggatttgct ccttttttaa cggcaaaggc tgtttcaccg attggagttc
    24361 cagagattgg agttttcaat ttttgacctt ggctgataga atatttgaga acaggttcat
    24421 catccataac ggcatcaatg gcaccagtgt ttaaactgtc atacattgaa gaaccatcag
    24481 caaaggtttt gattttgtag ccgtatttgc tttgattttc tgttaggaag gtttgagaag
    24541 cagttccgtt tttaacaccg actgtctttc cttttagatc ttcataagaa gcaatattgc
    24601 ttgattcttt gacaccaaga atggtattag cagtgtagta tgattctgag aagtcaaaag
    24661 ttgccttacg agcatctgtg acagacatac cagcgatgat accatcggct tgaccagctt
    24721 ggacagcact gatagcagca tcaaaaccag ggttggtgat ttcaatttca aaaccttggt
    24781 ctttagcgat tgccttaatc aattccatat caataccagt gtattggttg cttgaatttt
    24841 ggaaaacaaa aggtgcaaaa gaagaatcgc tggcaatgat atatttagcc ttaacaggaa
    24901 tagcttttaa tcctgcgaga gtagttgtag ttggcactgc tgaagatgat gaagcagtcc
    24961 atttcttgat aattttatca agactaccat cttttttcat ttcagacaag gcttggttaa
    25021 attcagtaac caggtgctcg tatttacttc cttttttcac accgaaagca aaacttccta
    25081 cagcttcacc atccatttca atatggaggt cttgaccttg gttaatggca tattcgataa
    25141 caggtttgtc atccatcatg gcatcgatgg caccagcact caagctgttg ttcattaaat
    25201 caccagtgtc aaatgtttta atagtaaagc cgtatttatc tttgattgtt tcaaggaaac
    25261 gttgagcggc agttccgttt ttaacaccaa cggttttgcc agttaattgg tcgtacttgc
    25321 taattttgtg tgactttgta gtagcaatga caacttttgt atcatagtaa gtatcagaca
    25381 tggtgaagac tttttcacgt tctttagtct ttgtcatccc tgccatgata gcgtcggctt
    25441 gcccagcttg aaccgcattg actgctgcgt caaatccagg ataggacatc tgaatgttcc
    25501 agcctttaat ctcagcgact ttgttaataa tgtcaacatc aattccttta taagtttgat
    25561 ctgaatcttt aaactcaaaa ggtgcatagg cggtatcaga aacaatctta atcgtttctg
    25621 ctttggcaat acctaatgag aaaattggga ataaaattag caaaaatgct agaaattttt
    25681 tcttcatttt tagtctcctt ttccgaatat tctctcatta tatcagaaaa agtaaaaaaa
    25741 ggcaaatttt tatatttttc gtgtcagaaa atataacatc gattttttcc tttccttgaa
    25801 ttgctattaa aaagtgctat aataatagta tatatagaag aaaagaggac ggggatatga
    25861 agaacaaaag aatatttaaa gacttccaag cttcaaaaat gagtttaaac atttacacaa
    25921 gccccttgtt agcctttgtt tttgtcttca taggagagtt tgtggctttt actttgtatg
    25981 gtattggctt gttagctctc atcggacttg ctagaaattt tggagaggct ggtcaaaatc
    26041 ttgcaagcta cttgcagacc ttgcatcaga gcttgacgga taaaacaagt gactttcgtt
    26101 taattttagg attactggcc tttggtttta ttcttaacac tgtgttcaga tggacaagaa
    26161 aagttgagaa aagacctatt cgaaccttgg gattttatag agagaatttc ctcagcaatc
    26221 ttctgaaagg atttagtcta ggcctggcac tttttcttct gaccttgtta ggtttagtgg
    26281 tcttaggtca atatcgtttg gaatccattc acttgaatcc ttattctctt gcctttgtcg
    26341 tctttactat cccattttgg attttacagg ggacagcaga agaagtggtg gcccgtgctt
    26401 ggctacttcc tcaattggcc tcaagaacca atctaaaact agctattctt atatctagcc
    26461 tgttctttac cctgcttcat atgggcaatt ctggtctcac ccctctatct ctagtaaatc
    26521 tctttttatt cggagttgcc atggctcttt accttctcaa aactgataca gtttggggtg
    26581 ttgcaggtat tcatggtgct tggaattttg ctcagggtaa tctctttggg attttagtta
    26641 gtggtcaacc gtcaggaacg tctctgatga cctttttacc acaaggcaat caagattggc
    26701 tatcaggtgg ttcttttggc atagaaggtt ccattatgac aagtctggta ttactactgc
    26761 tgattgtcta tcttgctaat aaattaaaga aagaaaatga aaggatgtga cttcggtccg
    26821 tccttttctt cgtgaaaata ctataagtat gctaaaatag gaatagcaca tggagagagg
    26881 attcttatga tcaatcacat tacagataat caatttaaac tagtatcaaa atatcaacca
    26941 tcaggagatc aaccccaagc tatcgagcag ttggtggata acattgaggg gggagaaaaa
    27001 gctcagattc tgatgggggc gactggaaca gggaagacct atactatgag tcaggtcatt
    27061 tctaaagtca ataaaccaac tctggttatt gcccacaata aaactctggc tggtcagctc
    27121 tatggggagt ttaaggaatt tttccctgaa aatgcagttg agtatttcgt atcctactat
    27181 gattattacc agccagaggc ctatgtccct tctagcgata cctatattga gaaggatagt
    27241 tctgtcaatg acgagattga caagcttcgc cactcagcta cctcagccct tttggagcgt
    27301 aatgatgtta ttgtcgtggc ctcagtctct tgtatctatg gtttgggttc gcccaaggaa
    27361 tacgctgata gtgtcgttag tctccgtcct ggtctagaga tttctcgtga taaactcttg
    27421 aatgacttgg tcgatattca gtttgaacgt aatgacattg atttccaacg cggaagattt
    27481 cgcgttcgtg gggatgtggt agagattttc ccagcttccc gagatgaaca tgcctttcga
    27541 gtagaatttt ttggagacga aattgaccgt attcgtgaag ttgaggctct gacaggtcag
    27601 gtgttgggag aagtggatca tttagcgatt ttcccagcga cacactttgt gaccaatgac
    27661 gaccacatgg aagttgccat tgcaaagatt caggccgagt tggaagaaca attagctgtc
    27721 tttgaaaagg aaggtaaact gcttgaagcc cagcgtttga aacagcggac agagtatgat
    27781 atcgaaatgt tgcgtgagat gggctatacc aatggggttg aaaattattc tcgccacatg
    27841 gatggacgga gcgaaggaga gcctccttat acgcttctcg acttcttccc agatgatttc
    27901 ttgattatga ttgacgagag tcatatgacc atagggcaaa tcaagggcat gtacaatgga
    27961 gaccgttcgc gtaaagaaat gctggttaat tatggtttcc gtttgccgtc tgctttggac
    28021 aatcgtcctc tccgtcggga ggagtttgag agtcacgttc atcagattgt ttacgtttca
    28081 gcgacacctg gtgactatga aaatgaacag accgagacag tgattgagca aatcattcgt
    28141 ccaacgggac tcttggatcc agaggtggaa gtccgtccga ctatgggaca gattgatgac
    28201 ctcttgggtg aaatcaatgc ccgcgttgaa aaaaatgagc gtacctttat cacaactttg
    28261 accaagaaaa tggcagagga tttgaccgac tacttcaagg aaatgggtat caaggtcaag
    28321 tacatgcact cggatatcaa gaccttggaa cggacggaga ttatccgtga cctgcgcttg
    28381 ggtgtctttg atgtcttggt cggaattaac ctgctccgtg aaggaattga cgttcctgaa
    28441 gtgagcctcg tagctattct cgatgctgac aaggaaggtt tccttcgcaa cgaacgtgga
    28501 ctcatccaga ctattggacg tgctgctcgt aacagtgaag gccatgtcat catgtatgca
    28561 gacacggtta cccagtctat gcaacgtgct atcgatgaaa ctgcccgccg tcggaaaatt
    28621 cagatggcct ataatgaaga gcatggtatc gtaccacaga caatcaagaa agaaatccgt
    28681 gacctgattg ccgtgaccaa ggcagttgct aaggaagagg acaaggaagt cgacatcaat
    28741 agcctcaaca aacaagagcg caaagaactc gtcaagaaac tagaaaaaca aatgcaagaa
    28801 gccgtcgaag tgcttgactt tgaactggcg gctcagatcc gtgatatgat gttggaagtc
    28861 aaggccttgg attaggggaa tagtatgatt tatttaagaa agttaaagag agaagatttg
    28921 atgtctttat gggaaatggc ttattcacaa cttaatccag tttggaaaca gtatgatgct
    28981 ccctattatg atgattatca gtatttttca aattttaaag aattcgaact acaaaaatca
    29041 gaatccattt taagcaactc aaatcgcctt ggtatttttg ttgatgataa actagttggg
    29101 actgtttcgc gttattgggt atgtaaacaa acaagatgga tggaattggg aattggtatt
    29161 tatgataaaa aattctggaa cactggtatt gggaaagttg ctatgttgca gtggatagat
    29221 aggacgtttc aggattactt ggagttggag catctgggtt tgacaacttg gtcagggaat
    29281 attggtatga tgaaacttgc tgaaaaatta agaatgaaaa aagaagctca tattccaaaa
    29341 gttcgttatt atcaaggtaa atattttgat agtattaaat atggtatttt gagagaagac
    29401 tgggagaaaa taaatgacgg ttattatcaa atcaatggaa actcctaaag agatagaagg
    29461 taaatccctt gttcactggc aaacgtggag agagtcttat gatgaccttt tgcctgcgga
    29521 atttcaggat acaatgacat tagaaagatg tcgattcttt agtcaaaagt atccagaaaa
    29581 tacattgatt gcgatggatg gcgtgaaggt ggttggtttt atcagttatg gcaattttcg
    29641 tgatgagact attcaagctg gtgaaattat tgctttatat gttttaaaag actattatgg
    29701 aaaaggtatc gcacaaaagt taatgaaagc agctttgact gctcttaatc atttttctga
    29761 aattttctta tgggtattga aagataacaa gcgcgccatt gctttctatc aaaaaatggg
    29821 ttttactttt gatggacaag aaaaaatact tgaacttgga aagcctataa aggaaaaacg
    29881 aatggtgttc tattctaaat aattttaaaa aagtaaaaga taatatctct ggtagtaagt
    29941 ctgaaaattt aataaattag aaagcgagta aatttatgtc ccgttcccaa ttaacaattt
    30001 taacaaatat ctgtctgatt gaagacctcg aaactcagcg cgtggtgatg cagtatcgcg
    30061 cccctgaaaa caatcgctgg tctggttatg cctttcctgg aggtcatgta gaaaatgatg
    30121 aggcttttgc ggagtctgtc attcgtgaaa tctacgaaga aacagggttg actatccaaa
    30181 atcctcaact tgtcggcatt aaaaattggc cactagatac aggtgggcgc tatattgtca
    30241 tttgttataa ggcgactgag ttctctggta cccttcaatc ttcagaagag ggagaagttt
    30301 cttgggtgca aaaagaccag attccaaact taaatctggc ctatgatatg ctaccattga
    30361 tggaaatgat ggaagctccc gacaagtcag agtttttcta tcctcgccgt acagaagacg
    30421 attgggaaaa gaaaatcttc tagtctttta ctaaataacc tagctgatcc aaggcctcct
    30481 cgatatagtg gaggtcttgt tgtgtttcgg cttcgactag gtggtaatgg atgccatctg
    30541 tcaattcaga tagaggtcta aagtcagaat gctcgacttg ttctagaaaa tgttgcacat
    30601 ctctgcgaca agacagttta agcaaggttt caatttctcc ataaacggga tggtcaatca
    30661 aggtattctg gacatgccca ccattatcga caatagcaag gagttcctga ccgatttctt
    30721 caacttcatg tttcactttg aaaagtttgt gaacataagg attggtatca atttgcttat
    30781 agatgtagcc acgattggtg gataggatag gagcgccatc ggctctcaaa attgcaatgt
    30841 cctgcacaat gacctgacgt gtgacatgaa aatgttccgc caaactttgg ccattaaggg
    30901 ctttaggagc ttctttcaag agttggagca gggcttgttt gcgatctttt gtcatagctt
    30961 ttccttttaa cggcgttttc gaagcacttt atagacagct agtgctaatg tatagtctac
    31021 catactatgg ataattgtgc caaatccaac tagtacaaat agaacataga acatattttc
    31081 tacattggta cccgaagttg cgtaaaaaag gacacaggct aatacttcag caagggcatg
    31141 aacaacagcc aaaacaaaat tgaaaaccca ggaagatttt ggtttatcta gggtatcggg
    31201 gaatttttgt aggtaaagag ctcctaaagc accaaaagat atatgggaaa aagcccgaaa
    31261 aacgataacc atgggatagc cagccatcaa aaatccaaaa ctagaggcta ggatgacaaa
    31321 aactgccatc aagggcgaca agaacatggc tataaaaata gcgatgtggc tccccaaagt
    31381 ataggaagca ggtggaatga caatcttgaa aggcataaca attggaatca aaatcgcaat
    31441 agccgttaaa agggctgtca ttgtcataaa ttgtgtcttt ttccgtgtat tcacaagaat
    31501 ctccttttta actgcatata cactagtatg gtacaataaa ccagacaata aagcaagaat
    31561 ttacttgggt ttatagatca ttttttagtt aaaagttata gtagattgaa actagaatag
    31621 tccacctcta cttctaaaac attgttagaa atcgatttga ctgtcctgat cgatttgtcc
    31681 tgttcttatt tcgttttact atagtaaaga tttcattaaa aagaaactgt atagagcaaa
    31741 atctccacct tcaggtttga aagcggagat tgtttttatt ttttcaaggt ttgtagtcgt
    31801 ggaacaatgg ctagggttag aattgcagaa atgaccaatt cagcaattga atttgttgag
    31861 ataacggttg ccagaagaag ttggatattt ccattataaa catttccaaa taggaagaag
    31921 attcctccaa ggacaaagat agtatttgtc aaggaaccaa gagccccagc taaaatcaga
    31981 ccagtcttgt ttttcatcag tttatagact aagtaaggag ttaaaccaat caaaatacgt
    32041 gggacaatgg caatgatagc tgagtagatg tttccgtttg gtacgaaggg agagaagagg
    32101 tagcttgtcg gtagaatcgt aatcgtgtta accgtcaagc taagtaatcc catcaaaaat
    32161 ccaagtgtaa ccccaactcg tggaccataa ataatgctgg caataatgac aggaatatga
    32221 acaatggtcg gtttgattgg aaatggaaaa aggttaaaga taagtgagct cagaaagtgt
    32281 atcacgagca tggtagcaaa aaagatagca atgggtgcaa tattagagcg ttttttcatc
    32341 gatagtttcc tttattcttt ctaaaataat tgtgaggtca gctaaagctc ctcgtccgtg
    32401 gtctccacaa gctagtaggg attccttagg agcaatcagc tgatagccgt aggtttctaa
    32461 tgttttcaga ttattctgag ttactggatg gtcatacatt tttgtattca tagcaggagc
    32521 tattagtttg ggaatatgac ttggtagggc tagagctgta ctggttacca tgttgtccgc
    32581 aaatccgtga gctagttttg caatagtgtt agcagttgca ggtaccacga taaataaatc
    32641 tgcttttttt ccaagttcga tatgattgac ctgatcagga tagggttctt tcatgacatc
    32701 caagtggaca ggattctgtg agagtacctg tagtgtcaaa ggttggataa actctgtagc
    32761 agcctgagtc attaagacag tgacttgatg gccttgtttt tttagagaac tgactaaatc
    32821 tgccgactta taagaggcga ttgaacccgt tacagccaag agaatgtttg ccatagtttt
    32881 cctttctaag aatgataggc ttgaattttt tcaaggagga gttctgcaat ttcttcttta
    32941 gtctggactg tttgaagctg atttttctca acaaatatag ctcggtgctg acctgctgaa
    33001 atttgagtca ggtcattcgc gatgattaaa tctgcttgat tcttgataag actttttcgt
    33061 gcaatgtcaa ccagatgatc ttcggtaaca tcaaccagca gtttgaaacc aatcagatga
    33121 atagtaggat tccattcctt gactagggat atgattttgg gtgtcttttt aaggaacaaa
    33181 acctgaacct catcagttga agaaatcttg gcctgatgat tctgcttgct taaaaattct
    33241 tttagattgg agctagcctg aacttcctca agccctgtca tataaacagg agtgtagtca
    33301 gaaacagcca ttgagtggat caagacctga taatcctgaa cacgttcttg catttctatt
    33361 agaaggtcct tggtattggt aatttctcga atacttaggt taggatgagg ctctggcttc
    33421 agagctcgtt ttgtcgtaat taaacaaact tcatgccctg cagaaagcaa agtctctgtg
    33481 ataattttcc ccaagtgacc tgtagaatgg ttagtgatag agcggacgct atcgatagct
    33541 tcactggtac cgcccgatgt aactaaaatt ttcatagcac tattgtacac aaaaataagc
    33601 ggtaagtaaa atgaaagtga taaatttttg gtaaaaacga agatttacta tagtttcaaa
    33661 ctataaagcc atataaaatt taagaaagga ctctaaaagt cttaaaaaca gagatattta
    33721 cgaacgttta gagagtttta agatgttaaa aatcttgttt tgtgatataa tgaattatca
    33781 tataagaggt tagaggaatt ttgaatgaaa acagatattg aaatcgcaca gagtattgag
    33841 ttgaagccaa ttgttgatgt tgtagagaaa cttggtattt cttacgacga tttggagttg
    33901 tacggaaagt acaaggctaa actcagcttt gataaaattc gggcagttga gagcaatcca
    33961 gtcggtaaat tgatcttggt tactgccatc aacccaacac ctgcaggtga aggaaagtcg
    34021 acgcttacca ttggtcttgc ggatgccttg aacaagattg gcaagaaaac catgattgct
    34081 atccgcgaac cgtctcttgg tccagtcatg gggatcaagg gtggtgctgc tggtggtggg
    34141 tatgcacaag ttctgccaat ggaagacatc aacctccact ttactggaga tatgcatgct
    34201 attacaactg ccaacaatgc cctttctgcc ttgattgaca accacttgca ccaagggaat
    34261 gagctgggaa ttgatcaacg tcgtatcctc tggaaacgcg ttgtggactt gaacgaccgt
    34321 gcgctccgcc atgtgactgt tggtcttggt ggtcctctaa acggtattcc acgtgaggat
    34381 ggttttgata ttacagttgc ttcagaaatc atggcaattc tttgcttggc aacggacatc
    34441 gaggacttga aacgtcgttt ggcgaatatc gttattggtt atcgctatga ccgtacgcct
    34501 gtttctgtag gtgatttgca ggttgagggt gccttggctt tgattttgaa ggatgctatt
    34561 aagccaaact tggttcagac aatttacggt acacctgcct ttgtacacgg tggtccattt
    34621 gccaatatcg ctcatggctg taactctgtt ttggcgacga caacagccct tcacttggct
    34681 gattacactg ttactgaagc tggttttggt gcggaccttg gtgctgagaa attccttgat
    34741 atcaagacac caaacttgcc aacatctcca gatgcagttg ttattgtcgc aacccttcgt
    34801 gcccttaaga tgaatggtgg tgtggctaaa gacgctctga ctgaagaaaa tgtagaggca
    34861 gttcgtgcag gttttgctaa cttgaaacgc cacgttgaaa atatccgtaa gttcggtatt
    34921 ccagcagttg tagctattaa cgaatttgta tctgatacag aagctgaaat tgcagtctta
    34981 aaagaactct gtgcctcaat cgatgtacca gttgaattgg ctagtgtctg ggctgatgga
    35041 gcagaaggtg gagtagcact tgccgaaaca gttgttaaga caattgctga aaatccagct
    35101 aactataaac gtttgtacga taatgacctt tctgtccaag aaaagattga aaaaattgtc
    35161 actgaaatct atcgtggtag caaagtgaac tttgagaaga aatctcaaac acaaattgct
    35221 caaatcgttc aaaacggttg ggacaaattg ccaatctgta tggctaaaac tcaatacagt
    35281 ttctcagaca atccaaatgc gcttggagca ccagaaaact ttgaaattac cattcgtgaa
    35341 ttggtaccaa aattaggtgc aggcttcatc gttgccttaa ctggtgatgt tatgaccatg
    35401 ccaggtcttc caaaacgtcc agcagctctc aacatggatg ttgaaagcga tggaactgta
    35461 ctaggcttgt tctagtggat tgaaattgac tttaagtgag tttggaaata atatccaagc
    35521 tcattttttc tcagactgca agcagttcat caataagatt tatactcttc gaaaatctct
    35581 tcaaactacg tcagcttcac cttgccgtag gtatatgata ctgactctgt cagttctatc
    35641 cacaacctca aaacagtgtt ttgagcaacc tgcggctagc ttcctagttt gctctttgat
    35701 tttcattgag tataagtaga tagaaaagtt atatactatc tattgaaaat attataaatc
    35761 agatacaaag acaggtgaaa ccttctgtgt tatactagag atatgttaga tttgaaagaa
    35821 tacggtatcg tcatgtggcc ggaggagaaa gtcatttctt tccgtgagaa acttctcgct
    35881 tggtatgatg aaaacaaaag agatttgcct tggaggagaa gtaaaaatcc ttatcacatc
    35941 tgggtatctg aaatcatgct tcagcagacc agggtggata cagttatccc ttactacgaa
    36001 agattcctgg actggtttcc aactgtcgaa agtctggcaa ctgcgcctga ggagagttta
    36061 ctgaaagctt gggagggctt gggctattat tctcgagttc gcaatatgca ggctgcagcc
    36121 cagcagatta tgactgactt tggtggccaa tttccaaata cctatgaagg aatttccagc
    36181 ttgaaaggga ttggacctta cacagcagga gccatttcca gtattgcttt taacttgcct
    36241 gagccagctg tagatggtaa tgtcatgcgg gtcttggcgc gtctgtttga agtcaaccac
    36301 gatattggga ttccaagtaa tcgaaaaatt tttcaggcaa tgatggagat cttgattaat
    36361 ccggatcgtc cgggtgattt taatcaagcc ttgatggact tagggtctga tattgagtct
    36421 cctgtaaatc ccagacctga agaaagccca gtcaaggact ttagtgcggc atatcagaat
    36481 ggaaccatgg accgttatcc aattaaatct cctaagaaaa agccggttcc tatttatctt
    36541 aaagccttag ttgtgaaaaa ttctcaagga caatttttac ttgaaaaaaa tgaaagcgaa
    36601 aagctcttgg caggtttttg gcatttcccc tttatagaag ttgataactt ttcgcaagaa
    36661 gagcagtttg acctctttca tcaggttgcg gaagaaagtg tgaactttgg ccccagtcca
    36721 gaagagagtt tccagcagga ctatgaccta gatgttgatt ggcttgatgt ttgttttgat
    36781 acagtccagc atgtttttag tcatcgaaaa tggcatgtac agattgtagc aggtcaggtg
    36841 agtgacttcc atgatttttc agatagggaa gttcgttggc tttcaccaga agaattcaag
    36901 aattacccac ttgccaaacc ccaacaaaaa atctggcagg cttatgcaca agccaactta
    36961 gacagtagcc aagactagct attgtgtctt ctgactattt tttggtataa tagtagagaa
    37021 aaaggtgaac atatgaaaaa aatactaatt gtagatgatg agaaaccaat ctcggatatt
    37081 atcaagttta atatgaccaa ggaaggttat gaagttgtaa ctgcttttaa tggtcgtgaa
    37141 gcgctagagc aatttgaagc agagcaacca gatattatta ttctggattt gatgcttcca
    37201 gaaattgatg gtttagaagt tgctaagacc attcgtaaga caagcagtgt gcccattctt
    37261 atgctttcag ccaaagatag tgaatttgat aaggttatcg gtttggaact tggggcagat
    37321 gactatgtaa cgaaaccctt ctccaatcgt gagttgcagg cgcgtgttaa agctcttctg
    37381 cgtcgttctc aacctatgcc agtagatggt caggaagcag atagtaaacc tcaacctatc
    37441 caaattgggg atttagaaat tgttccagac gcctacgtgg ctaaaaaata tggcgaagaa
    37501 ctagacttaa cccatcgtga atttgagctt ttgtatcatt tagcatcgca tacaggtcaa
    37561 gtcatcacgc gcgaacactt gcttgagact gtctggggtt atgactattt tggtgatgtc
    37621 cgcacagttg atgtgactgt acgacgtctg cgtgagaaga ttgaagatac gcccagccga
    37681 ccagagtata tcttgacgcg ccgtggtgta gggtattaca tgagaaataa tgcttgattt
    37741 actgaaacaa accattttta ccagagattt tatctttatc ctgattttgt taggtttcat
    37801 ccttgttgtg accctcttat tactggaaaa tagacgtgat aatattcagt tgaagcaaat
    37861 caatcaaaag gttaaagatt tgattgcagg agattattcc aaggttcttg atatgcaagg
    37921 tgggtctgaa atcaccaata ttaccaataa tttgaatgac ttgtcggagg ttattcgtct
    37981 cactcaggaa aatctagaac aagagagtaa gaggctaaat agtattctgt tttatatgac
    38041 agatggggtt cttgcgacta accgtcgggg tcagattatc atgattaacg atacagccaa
    38101 gaagcaactg gggttggtta aggaagatgt tctgaataga agcattttgg aattgctcaa
    38161 gatagaagaa aactatgaat tgcgtgattt gattacccaa agtccagaat tgttgctaga
    38221 ttcccaagat atcaatggcg aatatttgaa ccttcgagtt cgctttgcct tgatacgtcg
    38281 agagtctggc tttatttcag gtttggtggc tgttttgcat gatacgacgg agcaggagaa
    38341 ggaagaacgc gaacgaagac tctttgtttc caatgttagc catgagttac ggactcctct
    38401 gactagcgta aaatcctatc ttgaagcctt ggatgagggg gctttgtgtg aaactgtagc
    38461 accagacttt atcaaggttt ctcttgatga gaccaaccgt atgatgcgca tggtgacgga
    38521 tctcctccat ctttcacgta ttgataatgc taccagtcac ctagatgtgg aactgattaa
    38581 cttcactgct tttattacct ttatcctcaa tcgttttgac aagatgaaag gacaggaaaa
    38641 ggagaaaaaa tatgagctgg tgagagatta tcccatcaat tctatctgga tggaaattga
    38701 tacagataag atgacgcagg ttgtcgacaa tattttaaat aatgctatta agtattcgcc
    38761 agatgggggt aaaatcactg tcagaatgaa gacaactgaa gaccagatga ttttatccat
    38821 ttctgaccac ggtttgggga ttcctaagca ggatttacca cgtatctttg accgtttcta
    38881 tcgtgtggat cgtgctagaa gtcgtgcaca aggtggtaca ggtctaggac tgtctatcgc
    38941 taaagaaatt atcaaacaac ataagggctt tatttgggcc aagagtgaat acggcaaggg
    39001 ttcaaccttt accattgtac tcccttatga taaggatgca gtgaaagaag aagtatggga
    39061 ggatgaagta gaagactaga atgagtgaaa taggctttaa atacagtatt ttagcgtcgg
    39121 gttccagtgg aaattctttt tatctggaaa cctcaaaaaa gaagctttta gtagatgcag
    39181 gcttgtctgg caagaaaatt accagtctgc tagctgaaat taaccgtaag ccagaagacc
    39241 tggatgccat cttgattacc catgagcatt cagatcatat ccatggagta ggcgttttgg
    39301 ctcgcaagta tggtatggat ctttatgcca atgaaaagac ctggcaagct atggaaaata
    39361 gtaaatatct tggcaaggtg gattcttcgc aaaagcatat ttttgaaatg ggtaaaacca
    39421 aaacctttgg agatatcgac atcgagagtt ttggtgtaag ccatgatgca gtcgcaccgc
    39481 agttctatcg ctttatgaag gatgataaga gttttgtcct cttgacagat acaggttatg
    39541 tcagtgaccg tatggcgggc attgtcgaaa atgcggatgg ttatcttatc gaggccaacc
    39601 atgatgtaga gattttgcga tcaggttctt acgcttggcg actcaaacaa cgaatcctat
    39661 ctgaccttgg tcacctttct aacgaggacg gtgctgaagc tatgattcgg acgctaggaa
    39721 atcgtactaa gaagatttac cttgggcatt tatctaagga aaacaatatc aaggaactgg
    39781 ctcatatgac catggtcaat cagctggctc aagctgatct gggagtcgga gtagacttta
    39841 aggtttatga tacctcacca gataccgcaa caccattgac agagatatag aaagaacgct
    39901 gagaaggtgt tcttttt
//
LOCUS       DAVKEV010000021        36637 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVKEV010000021 DAVKEV010000000
VERSION     DAVKEV010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36637
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.021"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(48..845)
                     /gene="psrA"
                     /locus_tag="VWZ68_001082"
     CDS             complement(48..845)
                     /gene="psrA"
                     /locus_tag="VWZ68_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEU9372113.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            complement(902..2182)
                     /locus_tag="VWZ68_001083"
     CDS             complement(902..2182)
                     /locus_tag="VWZ68_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9372114.1"
                     /translation="MRIKSIYWNFGQNKPEKSFRYIDTSSIDRKKNIINYKNLQYLSP
                     EQAPSRARKLVSQNSVLFSTVRPYLKNIAVVRELKEYLIASTAFIVLDTLLNETYLKY
                     YLLSDNFINRVNNKSTGTSYPAINDYNFNLLLIALPPLSEQQRIVEAIESALEKVDEY
                     AESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEE
                     GKIKKKDLDISIVSQGDDNSYYEEVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPI
                     YPVIAQKCNQWSGFSIDLARFIDPKTVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYH
                     ENKNPYGWAVADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLT
                     KTIKEYLIPLPPLPEQSRIVDKIEQFFAHIDALI"
     gene            2748..2867
                     /locus_tag="VWZ68_001084"
     CDS             2748..2867
                     /locus_tag="VWZ68_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEU9372115.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(2963..4309)
                     /gene="glnA"
                     /locus_tag="VWZ68_001085"
     CDS             complement(2963..4309)
                     /gene="glnA"
                     /locus_tag="VWZ68_001085"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEU9372116.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(4346..4702)
                     /gene="glnR"
                     /locus_tag="VWZ68_001086"
     CDS             complement(4346..4702)
                     /gene="glnR"
                     /locus_tag="VWZ68_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEU9372117.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(4779..5306)
                     /locus_tag="VWZ68_001087"
     CDS             complement(4779..5306)
                     /locus_tag="VWZ68_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU9372118.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRVRLFLEKKEK"
     gene            complement(5442..6638)
                     /locus_tag="VWZ68_001088"
     CDS             complement(5442..6638)
                     /locus_tag="VWZ68_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEU9372119.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(6728..11707)
                     /locus_tag="VWZ68_001089"
     CDS             complement(6728..11707)
                     /locus_tag="VWZ68_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEU9372120.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLHYQGHEVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELTTAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELTFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNKVLPKPTYQPTSDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            12000..13631
                     /locus_tag="VWZ68_001090"
     CDS             12000..13631
                     /locus_tag="VWZ68_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEU9372121.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGIGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNIIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(14172..15779)
                     /locus_tag="VWZ68_001091"
     CDS             complement(14172..15779)
                     /locus_tag="VWZ68_001091"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEU9372122.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENRN"
     gene            complement(16169..16756)
                     /locus_tag="VWZ68_001092"
     CDS             complement(16169..16756)
                     /locus_tag="VWZ68_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEU9372123.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(16884..17333)
                     /locus_tag="VWZ68_001093"
     CDS             complement(16884..17333)
                     /locus_tag="VWZ68_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9372124.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(17338..17727)
                     /locus_tag="VWZ68_001094"
     CDS             complement(17338..17727)
                     /locus_tag="VWZ68_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEU9372125.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETNQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(17755..18381)
                     /locus_tag="VWZ68_001095"
     CDS             complement(17755..18381)
                     /locus_tag="VWZ68_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU9372126.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKNPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVFASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(18395..18958)
                     /locus_tag="VWZ68_001096"
     CDS             complement(18395..18958)
                     /locus_tag="VWZ68_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9372127.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(19123..19272)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(19332..19835)
                     /locus_tag="VWZ68_001097"
     CDS             complement(19332..19835)
                     /locus_tag="VWZ68_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEU9372128.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(20028..20858)
                     /locus_tag="VWZ68_001098"
     CDS             complement(20028..20858)
                     /locus_tag="VWZ68_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU9372129.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRLLV
                     LIAIFSVFLLYLSEIHFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGAYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(20843..22525)
                     /locus_tag="VWZ68_001099"
     CDS             complement(20843..22525)
                     /locus_tag="VWZ68_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9372130.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHCPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLRTELVKETPELQSLFRLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKALSSFIQTEGRYLWEGQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEQEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQQGHTIVMITHDMQLMLDYSDRALVMVDGELIA
                     DTDPASLLSNPELLVKANLKETSIFNLAKKLDVDPLALTAFYKERREGCKLN"
     gene            complement(22627..22884)
                     /locus_tag="VWZ68_001100"
     CDS             complement(22627..22884)
                     /locus_tag="VWZ68_001100"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372131.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(22891..23439)
                     /locus_tag="VWZ68_001101"
     CDS             complement(22891..23439)
                     /locus_tag="VWZ68_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEU9372132.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(23454..24302)
                     /locus_tag="VWZ68_001102"
     CDS             complement(23454..24302)
                     /locus_tag="VWZ68_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEU9372133.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            24490..25839
                     /gene="trkA"
                     /locus_tag="VWZ68_001103"
     CDS             24490..25839
                     /gene="trkA"
                     /locus_tag="VWZ68_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEU9372134.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            25843..27282
                     /locus_tag="VWZ68_001104"
     CDS             25843..27282
                     /locus_tag="VWZ68_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU9372135.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMAFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMTIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLSLIFIVSLDSNDFLIVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(27407..29086)
                     /locus_tag="VWZ68_001105"
     CDS             complement(27407..29086)
                     /locus_tag="VWZ68_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU9372136.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGVIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSVMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QSISFVFLSLILVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEETSEIMPGELDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            complement(29155..30567)
                     /gene="lacG"
                     /locus_tag="VWZ68_001106"
     CDS             complement(29155..30567)
                     /gene="lacG"
                     /locus_tag="VWZ68_001106"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU9372137.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVQYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            complement(30577..30921)
                     /locus_tag="VWZ68_001107"
     CDS             complement(30577..30921)
                     /locus_tag="VWZ68_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9372138.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            complement(31089..32975)
                     /locus_tag="VWZ68_001108"
     CDS             complement(31089..32975)
                     /locus_tag="VWZ68_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEU9372139.1"
                     /translation="MVIRVFDQQKNTYSSFALEELRYYMNQVFNTDIELVEEKEADIF
                     VGLVNEEDGKDHIFISLNKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFIP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYKDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGQMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            complement(32977..34299)
                     /locus_tag="VWZ68_001109"
     CDS             complement(32977..34299)
                     /locus_tag="VWZ68_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9372140.1"
                     /translation="MNNILTFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRIFIQRGITIKMPNGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            34467..35690
                     /locus_tag="VWZ68_001110"
     CDS             34467..35690
                     /locus_tag="VWZ68_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU9372141.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPSVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTATKYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKKFDFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
BASE COUNT        11139 a         7873 c         6306 g        11319 t
ORIGIN      
        1 cataatcaca aaaatagcag gtagtcagtt tgaccacctg ttatttttta ccaattaaca
       61 attttatcta caatattttg ttgttcagta gctgttttcc ttagataaat tcgagtagtt
      121 tctatacttt cgtgtcccat caaatctgca agcaaggcaa tatcattata cttcgctaaa
      181 aaattcttag caaataaatg cctaaaagaa tgagggtaaa ttactttagg attcattttg
      241 tatttatcag cataattttt taactgttga gcaactcctc ttgctgtaat tggttcgtta
      301 aatttattca aaaataaata accacttcgg cgattttctg attctaacca actaagacaa
      361 ctatttctta attttttagg aatgtacagt ctacgaattt taccaccttt tgagtaaatg
      421 tcaaaataac cgatttctac atgctctact tttagtttaa taagttcact tacacgagcc
      481 ccagttgcac ctaaaaacca aacgacaaaa tgccatttta aaataccatc ttttttcaaa
      541 ctacgtttaa gaaaaaggta atcagcatgg ctaatgacat cttctaaaaa cggtttttgc
      601 tgtactttga caaattttaa tttcaaatca tcatgaccaa taaaagccag atatttattt
      661 actccttgta gtcgcaaatt gacagtttta ggtttaaaat tgtctaataa atatcctttg
      721 tattcaaata aatcttccat tttgagttcg taattctcca agaaaaatcg aacaccataa
      781 aggtacgaac gcacagtatt ttcagctaaa ccagctttct tcaaatgtaa ttcaaaatct
      841 ttcaacgtaa aactcctatc ttatgtttga tagaaattcc accgcacgta aaactattat
      901 actaaattag tgcgtcaata tgggcgaaaa attgttcgat tttatcaacg attctggatt
      961 gttcaggaag gggtgggagg gggattaaat attcttttat agttttcgtt aataattctt
     1021 tttgttttgt actacccgac gctttttctt caataactga ctgaacaata ggagaggaaa
     1081 gaaaattata gatgaaatgg caattaataa cccccgataa gactcttata actgtaacat
     1141 ggctatctgc aacagcccag ccataaggat ttttattttc atggtaaata gctaatcgtc
     1201 ctaacgtacc tagacctgtt gaattccaca ttaaatcacc atctcttagt aatctttctt
     1261 tctggtaact atgaactgtt ttgggatcaa taaatcttgc taagtcaata gaaaagccag
     1321 accattgatt acatttctga gcaatcacag ggtatatagg aatatttgaa tattttggag
     1381 acttccctct ttgaatgtag gaggttatat cgtttaacct cacccattcc caactttctg
     1441 gtatttcaca aggtacttcc tcataataag agttatcatc tccttgggaa acaatagaaa
     1501 tgtccaaatc tttcttttta atcttgcctt cttcaaagag tttttgtttt tctgctcgta
     1561 ttttttcaag taaaacttcg actgattcat catttgggtc ttgttcaact aattttcctt
     1621 gcatagcata ttgaagaata gattttttta gtttatctgg aaattcttta tctagctgtt
     1681 ctagtctatt ataactttca gcatattcat ctactttttc taaagctgat tcgattgctt
     1741 ctactattcg ttgttgttcg gatagtgggg ggagagcaat taataataga ttaaaattat
     1801 aatcattgat tgcaggataa cttgttccag tagatttatt attaacacga ttgataaaat
     1861 tatctgataa taaataatat ttcaaatatg tttcgttaag taaagtatcc aaaacaataa
     1921 atgctgtact agctatcaaa tactctttaa gttctctaac tacagcaata ttttttagat
     1981 atggtctaac tgttgaaaat aagacactat tctgcgaaac taattttcta gcacgggaag
     2041 gcgcttgttc aggtgaaaga tattgtagat ttttgtagtt gattatgttc ttttttctat
     2101 caatactaga cgtatctata tacctaaagg atttctctgg cttattttgc ccaaaattcc
     2161 aataaattga ttttatcctc acccactccc aagtatcagg aatatcataa ggaacatcaa
     2221 tttcttgagt acttccatca gcaaacttcc cataatgttt cttatgtgct tcaagtatat
     2281 aaaaaggcgt aaaaatacgc ctatagataa tggggttgaa ataggtttat tgttgatgag
     2341 attgtagata attcaatttt ttacttccaa tcgaatattc aaaacctcca ccttttctgc
     2401 ctgtaattgt tcatcataaa attcaatatc ttcaggattt tccccttggc aacctcggca
     2461 gaaatattct tccgctcgat caggattcaa aaatcgacaa gcacaaacaa aacagtcgcc
     2521 atcatcattt attgagataa tatagtagat tgaaataaga tgtaaacaaa tcgattagga
     2581 aagttaaatt agtttctaga aatttttagc agatgtagtg taccattcta gtctcaattt
     2641 actatggctt caaatatatc tttcgaaaaa atatttacag atgtgtaatt ttgaagcttg
     2701 caaaagttag taaacttgta gatttcgatt tgaagtaact tgttttcttg cccgatattg
     2761 tttttgaaat tgaatttttc catagtgact ccttaatttt cttctacacg tctgatgata
     2821 aatctaattc gcaaaagagt caagaggatt tttcgaaaaa taaatagcga ccgaaatcgc
     2881 tattttaagg gttataggta tttgatggct tagactgctg tgtgactgtt tacccacagg
     2941 caatctttct tctatattag tattagtaaa ggtctaaata attatcaatt tcccattgtg
     3001 aaacgaaggt tgcataactt gcccattcga ttcgtttggc ttcaaggaag ctagtgtaga
     3061 tgtgatctcc gagagcagct ttaaccactt catcttctgt caaagctttc aaagcgttgt
     3121 gaagagttga tggaaggtct gtaataccag cttccttgcg ctcttctgct gtcatgatgt
     3181 agatattttc ttcgatagga gctggtgctt cgattttatt ttcaatacca tacaaaccaa
     3241 cttccaaaag aacagccata gcaatgtaag ggttcgccat tggatccact gaacgcaact
     3301 caagacgagt tcccatacca cgtgaagcag gtacgcgcac aagtggcgaa cggttacgac
     3361 cagcccaagc aatgtaaaca ggcgcttcat aacctggaac caaacgtttg tatgagttaa
     3421 ctgttgggtt catgatggca gtatagttgt aagcatgctt gatcaaaccg cctaggaaat
     3481 ggtaagctgt ttctgacaac tgcattcctt ttggatcatt tggatcaaag aaggcgttat
     3541 ttccttctgc atcaaacaag gacatattac agtgcatacc tgagccagca ataccaaatt
     3601 ttggcttcgc cataaatgtt gcgtaaagtc cgtgtttgcg agcaatggtt ttaacaacaa
     3661 gtttaaagat ttgaatctta tcacaagcac ggagaacttc atcgtactta aagtcaatct
     3721 catgctgtcc aaccgcaacc tcgtggtgac tcgcttctac ttcaaatccc attttggtca
     3781 agacattcac aatctcacga cgtgtgttgt ccgcaaggtc agtaggtgcc aaatcaaagt
     3841 agccaccctt gtcattcact tcaagtgttg ggtccccatt ttcatccaac ttaaatagga
     3901 agaattctgg ctctggacca aggttgaagg atttgaatcc aacttcttcc atgtgacgaa
     3961 gagctcgttt caaattacca cgagggtcac ccgcaaatgg ttcaccttct gttgtataga
     4021 catcacagat cagacctgca acacttccat tttcatctcc ccaagggaag actgtccatg
     4081 tatccaagtc cgggtacaag tacatatccg actcattgat acgtacaaaa ccttcaatag
     4141 aagatccatc aaacataacc ttgttcgaca aaaccttatc taactgttca tctgtagcag
     4201 gaatttcgac gtttttcatg gttcccaaaa tatctgagaa cataagacga ataaaggtaa
     4261 catttttttc cttgacttca cgacgaatat ctgcagctgt gattggcata agttttctcc
     4321 ttaatctatg actacttgcg gttgcctaac cgcgaccaaa aggtgactgt actgaagcaa
     4381 aacgcccctg ttggaggagt tcattgtgaa gtgcacgacg tacttcagtc tgactaaccg
     4441 ctttcttgga tttcgcttca cgttcagcat attttttctt aatggcagcg atattataac
     4501 cttcagagat ataatctttg atttcaagca gacgatccat gtcattcaag gaatacatgc
     4561 gacgatttcc ttcgtttcga tcgggcttga tcaactcttg atcttcataa taacgaatct
     4621 gacgcgccga tagatcggtc aacttcataa cactgccgat aggaaaaaca gccatatttc
     4681 ggcgaaattc tttttccttc atttacaatt tccttctttc tgtctattat agtctaaaaa
     4741 aagacaaacg tcaattgata atgttataaa atgtaacatt atttttcttt tttctctaaa
     4801 aagagacgaa cacgatcaat atcgtaattt acgataattg cgacaaaaac tcccataaac
     4861 gtttctgata cacgcacaaa cacgtacgaa attgtctcac cacttggaat tgatagggta
     4921 atgattaaca tagctgctac accaccaata acccctgctt tgttattcat ggctacattt
     4981 gtcataatgg ttaacatggt gcagattgga acaactacca aggtcaccca aaaggcttcg
     5041 tggaaaaagg tatttaataa gaagaagacc aaggcataga gtccaccgat actatttcct
     5101 agaatacgcg aagtcccaaa atgaacactc tcatcaaaac tctccctcag gctaaaaacg
     5161 gctgtcaaag caccaatttg aagacctttc cagccaaaaa agccaaaaat caagagaact
     5221 agaaaaacag caatacctgt tttaaaggtt cgcataccaa gtttgaactg ggatttatcg
     5281 aatttatatt ttttaaaata actcataatc tcaactttct atttccattt tatcataaat
     5341 cggtgatttt tatgagtaat agttgagagg aagcgttttt attttaagca aaagaaaaga
     5401 ggaactttca tccctctctt ctttgatttg tttataaaat cttatttttc tgtcagggct
     5461 gcaagtcctg gaagaacctt accttcaaga agttccattg atgctccacc acccgtacta
     5521 atccatgaga acttgtctgc acggccaagg ttaatcgctg cggcagctga gtcaccacca
     5581 ccgatgattg atttaactcc tggttgtttc acgatagcgt ccatcacacc gattgtacca
     5641 gcttggaaat ctgggttttc aaatacaccc ataggtccgt tccatacaac tgttttggca
     5701 ccagtcaaag cttcgtcaaa tttggcgata gattttggac cgatgtcaag accaaggaag
     5761 ccttcagaaa ctgcttcacc ttcagtgtca cgcacttcag tgtaaccagc aaatgcgtta
     5821 gcttcttttg agtcaactgg caagatcaat ttaccatttg ctttttcaag aagagctttc
     5881 gcaacatcca atttgtcttc ttctacaagt gagttaccga tttcgatacc ttgtgctttg
     5941 tagaatgtgt aagtcatccc accaccgata aggactttat cagctttttc aagcaagttt
     6001 tcgataacac cgatcttgtc tgaaactttt gaaccaccaa ggatagccac gaatggacgt
     6061 tctggagttt caactgcttc ttggatgtag gcaatttcgt tttcaagaag gaaaccagca
     6121 actgcttttt caacgtttgc tgagatacca acgttagatg cgtgtgcacg gtgagctgta
     6181 ccgaatgcat cgtttacgaa gataccatct ccaagtgatg cccagtattt accaagttca
     6241 ggatcgtttt tagattcttt cttgccgtca acatcttcgt aacgagtgtt ttcaaccaag
     6301 agaacttgtc catcttcaag agcgttgatt gccgcttcca attcagcacc acgagtgaca
     6361 cctgggaaaa caacatcttg accaagtttt gctgccaagt cagctgctac aggagcaagt
     6421 gatttaccag ctttatcagc ttcttctttc acacgtccaa ggtgagagaa aagaattgca
     6481 cgtccacctt gttcgatgat gtacttaata gttggaagag ctgctgtgat acggttatcg
     6541 ttagtgatta cgccatcttt caatggtacg ttgaagtcaa cacgaacgag gactttttta
     6601 cctttcaagt caacgtcttt aacagtaagt tttgccatgt tacaaaaact cctttattta
     6661 ttttattcga aactattata tcacactttg gaaatataag gaaagatttc acaagatttt
     6721 tcgatattta atctttatct tctcttttcc gtctcaaggt caaggctaaa ctagcaagac
     6781 cgaggctggc taagcctgct attagggctt cattagcatc agctgttcct gtatttggca
     6841 attgtttgct tgcttcttct gatttaactg ctgtattttg agctggtttt tcctgtgtag
     6901 ctactactgc tggtactgtt tttacttttg ttccaatttc aacaatttct ggaatcgctt
     6961 cttggatgac ttctgttgaa cgaagacgac gctgaccgtt ttcatcaact tcaaagacat
     7021 gtcttaacag tccatctcgt ccctgtatga tgactcgttg ttccccaact agcatctcag
     7081 cattttcatg ctcttgacga tgaaaggcaa ccttttcctc ttgaacttcc aatttaggag
     7141 ccttttgttg atcagaagtc ggttgataag taggttttgg aaggactttg ttttgtggtg
     7201 ctggtttagc aggttgtggt ttttcagcag attcataaac aaaggcataa tgagtaaagt
     7261 gtggtgctgt aaagataaca tgactatccg tttgttcaaa agtcaattct actgcctctt
     7321 tgccttcagg taagaaaaat actttcttaa ctttcttatc tttttcaatt gggattttca
     7381 caatagaagc gtaagagaga tcaacatctt gacctttttc atccaaacct tctatttcaa
     7441 agacatgagc atcttctcca gcaaagtatt tcttctcttc agcacttgct tgaacacgct
     7501 ctactttcaa acccttgatg acagtcttct ctttatttga gaagtgtact tcaacacctg
     7561 ttttactatc agaaaagact gctggcttgt cttctttcaa taaagcaacc agatctttta
     7621 gactctgttt cgctgttgta agctcttctg gactcaaatc tactttttca accaaggcct
     7681 tgtttttctc aagaagcgga gctagggcag aacctgaagg atggtttggt ttggcagcca
     7741 agagttcttg aacctcacct gttaagcgat caagctctgt cttttcttcc gtaaatttct
     7801 cttgaccatt cagagcttta tgagcttctg tcaatttatt aagtcggtca ttgacttgat
     7861 cttgggtgct agtttcatgg tctttcaaca cttgttcggc cgcttcaatt gctttcaaga
     7921 aggcttcttt tacttctgat gaagcaaagt tatagaccac cttgttctta gcagcttcaa
     7981 cttctgctaa tttttgtttg aggtactcat cgttcaatgc tgcttttgga gataccaaaa
     8041 catcaaagct aacttcatgg ccttggtaat gaagcgtcaa ggtttgacga ccagtctttt
     8101 gagcatcgta accagaaatt tcaactccct catcagtaaa ggaatgttct tccatggtgt
     8161 cattgctata agccactgca aagcgtcctt cagacaagtc taagctatca ccaactaggt
     8221 aatctttttt cggttcctga cttacttcaa ttcccaaaat agttttcgga cttgcttcgt
     8281 cttggccagt gacagtcact gacaaattag catttaccgg ttgtcccaaa tattggagag
     8341 taagattctg ttctccctta tgatgcgtat caaaacctga tactgataca cctgcgtgag
     8401 ttaggcgaat gagttcgtcc tcagttcctc cttcatactg aactcgaaga acaccacctc
     8461 taaggtccaa atcctcccct tcggcgtagc ttgttttctt aggtcctgtt tctaggctga
     8521 ctgacttgat tcttctgtca tcttttggaa cggaaactgc taggacatta ctaatttcct
     8581 tgcctggcaa ctgggtacga taataaagaa gaccagattg atttgtcaaa tccaatggtg
     8641 cacttgctag gtctcctcca acttcgctct tcaaggttgc gagcggagtt tgagaatttg
     8701 gattatcata aacggtaata gttgctccag ccggtacatc tgcaaagcca acttgtacct
     8761 tgttattgcc tagagaacgg gctgcagcct tggccatcgg aatattgaca ctctcagtat
     8821 caagcttttc atacattttc cagttataga tacgaatagc cttccatgga gttccattgt
     8881 cagaagtgac aacattcaag cgccagtctt gagcagtgat tggtttatca agagtgatat
     8941 ctgtcacgtg tgctttgtta ccacggactt ccttagctag cttccactca ccatctgcat
     9001 ctttataata aaggtcaaag tctttagtgt tcatcaagcc atcgttaaca gactcaccac
     9061 cagctcctgc atgatccatg acccatctaa caacggtacg tggcttggtc aaacgaatat
     9121 ccacactacc actcaactga gctgaagacc atttatctga caagctagta atggtaccgt
     9181 tcaacatacc ttcaatacct tctccacctt cagtcttagg gaaagtacta tcaataactg
     9241 ttgcacctgg aacgatattt tcagctagtg gttttggtag gctggtatct tttacagtca
     9301 taccccaatc aaaggttgtg gttgcagctt ctgaacgaac tccattttta ccgactgcta
     9361 caaccttcag ttcttgagtt gtaccctgag cacttgctga gcggctaact tttggtagat
     9421 aaatagttgt agaagatgag ccagttagta atttccagct gtctccatct ttttcataaa
     9481 cttcatagaa atctgcatcc ttgttgcctt taaattgcac aactgcttcc gcttcttggg
     9541 catttttaag agattgtttc actacagaaa agcttgtcgg cgattgtggc tcttggtgat
     9601 tgtccgagat agttaattgt cctaggttaa actgataatc ttttacagca ccttcatgct
     9661 cgaaaaatag tttgactgca tagatggttt tacccgctag tgagctaaga tcaaattctt
     9721 catttgtcca gttgtcagaa agggttagct ctttccatgc atctgcatca tcgaatttgt
     9781 agtctggagt tgtagagaat gccatataaa ctttagaacc ttttcctccc ttgtgggcaa
     9841 cacgaagttt ggtcttctca gttacttcta acttagtaga ataaagtctc acatcctgat
     9901 ctgtcttacc agctacatca ccagagaatt taagggaatt tccgccatta taggcatctg
     9961 taaaatcata ttctgcacga agtttttccc ctgttgaagt ctgccaccag cgccatgttg
    10021 gaagaacacc tgatactgaa cgataattcc actcagaatc cttagaaacc ttaccatcta
    10081 cgaaccattt tttaccatga cctgtattaa aagaagtagt aaaagtatta cctaccgctg
    10141 gcgtacggtc cgcaactagg ttagcaatac cataccaatc tttgtcacct ggtttttggc
    10201 cagtggggtc tccttgataa cctgtaaaga agatatcttc atttttatga taatcttcac
    10261 cagtttttcc taaacttgta atggtatctg gggcaaataa accaagagaa aggcgcaatt
    10321 tcccattttc gtctaaaatg tcattccact taacctttgt cttgtaggaa ccaccctgtt
    10381 gcaattccaa acctgcaaat acatcataag gattacgacc aatccagttg gcagttgcaa
    10441 tagtgtaatc atttttagcc ttatcccagt taaagttagc aaagaagtta tctgccggaa
    10501 ccttatctcc ttctggttgc atgaattggt agttgtattc tcccaaacca tcttgatggt
    10561 aacgtccata gttataggtc atggcatcat accaagaata cttgattgga tggtttacct
    10621 tagcagcata ttccttgcta tagagcataa actggcgcat cttttctcca agaggtttaa
    10681 ccaaatctcc agttgtttct tggttgatga aatagccatc atagccataa tactttgcca
    10741 tgtctaccaa tttacgggca attgggaagc taccatctgc gtcttgcttc aaagcttcag
    10801 caaatctttc ttgatctgca atactattag accagttgaa gaagagtgta ccgtatacag
    10861 gaaccccgtt acggtgacct gcatcaataa cgtcaggagt tggtacgaga ccttcccaga
    10921 agaccattga atctagatat tgccaatagt caaaagcata ggccttgaac tcttctccac
    10981 caacagaagc atggtctttt gctttagaat tggtgtttga taaggcttga acttttgctt
    11041 ccttgctagc tttttcattg actaaatgac ctgtccgacg tgaagcgagg acaacagatc
    11101 cgcggttaat agcatcgtct tcacgagcac ctggttccca ttttaacaat tcttcccaag
    11161 aattaaattt gatttccttt ggttttaatg ttttttctgt atttttaggg acatctggct
    11221 ggacttcttt ttcagtctta ttagcttctg ctgctggttt agactcatcc ccttggttag
    11281 ttgcttcggg ctttgcttct gtttccttgt cagacttagg ttttgcttct gcagatggtg
    11341 tttctgcaac cacctcactt gctttttcct ctggtttagc tgcgctagct gcttctgcag
    11401 tttcagtagt tgcagcttca ttgcttgctg gcgaagcagt ttcagatgct atcgctactc
    11461 cttctgcctt ttctagcttg ttttctctag catgttcccc ttcattctgc ttatcagctt
    11521 cattggtcga atgctcactc tctcctgaaa caagctctgt attagctccg ctattttcag
    11581 gaactgcagt ttcttcagcc aaggctggac cagcaaataa aacagcacca atcatcagcg
    11641 agcaggctcc tactgataac ttacgaatac tgtaacgaca acgtctttca aaaaatggat
    11701 tcttcatttt ctcctcctaa aagattgatt ttgttgtttt caagaaagcg ctttatattc
    11761 tgtagttttt tatcaaactc tagaaccatg ataatcacat ttttatccta aaacattttt
    11821 agacaaaaaa caatagctgc tttcataaat ctaaaataag gttaaaaact cttaaaaata
    11881 atacacttat caattataat tttcttttac aaacttgacg ttaacacttg ttagatttac
    11941 ttttatcctt taaaatagaa taggagatat tccgcgatta tttttcggag gaaaaagaaa
    12001 tgtccattaa ttggcaggaa attttatttc actttttagg tggtctgggg ctattcttat
    12061 atagcatcaa gaccatggga gacggtttgc aacaagctgc tggagatcgc cttcgttttt
    12121 acattgacaa atatactagt aatcctttct ttggagttct ggttggtatt gggatgactg
    12181 ctctaattca gtctagttct ggtgtaacag ttattacagt cggcctggtc agtgccggtc
    12241 tcttaacctt acgtcaggct atcgggattg tcatgggtgc taatattggg acaactgtca
    12301 catcctttct catcggtttt aaattaggta actatgccct acctatgctc tttatcggtg
    12361 ccgtctgtct cttttttacg aaaaatcgga cagtcaataa tatcggacgc atcctctttg
    12421 gtatcggtgg tatctttttt gccctcaatc tcatgagcgg cgcaatggct ccactcaagg
    12481 atttacaggt ctttaaggac tatatgattg agctaagtaa gaatcctgtt ttgggtgtct
    12541 ttgtcggtac tggcttgacc ttgctaattc aagcttcttc ggctaccatt gggattttac
    12601 aaaacctcta cgccggcaat ctaattgacc tacagggagc tttgccagtt ctatttggtg
    12661 acaatatcgg gacaaccatt acagccatca ttgcctcttt aggggctaat attgcagcta
    12721 aacgggtagc aggagctcat gttgccttca acattatcgg aacagtcgtc tgcgttattt
    12781 ttctagttcc ttttactgtc ctgattcatt ggtttgaagc tacgctaaat ctagcaccgg
    12841 aaatgaccat cgcctttgct cacggaacct ttaatattac caacaccatt gtccaatttc
    12901 catttatcgg agctctggct tactttgtaa ccaagattat tcctggagag gacgaggttg
    12961 tcaaatacga acccttatat cttgatgaac atttcatcaa acaggcccca tctatcgctc
    13021 taggaaatgc taagaaagag ctcttgcact taggaaacta cgctgctaaa gcctttgacc
    13081 tttcctataa gtacatcatt gacttggatg aaaaagttgc tgaaaaaggg cataaaaccg
    13141 aagaagcaat taacaccatc gatgagcaat taacacgtta tctcattgcc ctttcaagcg
    13201 aagctctcag ccaaaaagaa agtgaagtgc ttaccaatat ccttgattcc tcccgtgatt
    13261 tggaacggat tggagaccac acggaggctc tactcaatct gactgactat cttcaacgga
    13321 aaaatgttga attttctgat gccgccttga aagaattaga ggaagtttac cgccaaacta
    13381 gtgactttat caaagatgct ctggatagtg tggaaaacaa tgatattgaa aaagcacgca
    13441 gtcttgtaga acgtcatgaa gcaatcaata agatagaacg tgttctcaga aaaacccaca
    13501 tcaaacgcct caacaaaggc gaatgttcaa cacaagctgg ggtcaacttt atcgacatca
    13561 tctcacacta cactcgtgta tcagaccacg ctatgaacct tgctgaaaag gtttttgcag
    13621 aacaaatcta ataaccaaga agctatccat cataattgga tggcttctta ctttttccta
    13681 agcaagacta ggctgaatga aactgaaaga gtattctgca gatatatagt atattgaaac
    13741 tagaatagta cacctctatt tctaaaacat tgttagaaat cgatttgtcc tgttattatt
    13801 tcattttact ataatggatt aaattaaaaa agtatagtgt attgaatcta taacagtcca
    13861 tcttgactgc taaaatattt ctataaatta atttgacttt tctgatagag atgttcacat
    13921 cttatttcaa ttcatgatac aatccagttc ctaaaacttt gctagaaatt aatttggctt
    13981 tccgaattaa tttgttcaga ttttatttca tttcaatata ctgataaatc cattcactag
    14041 cacagggcaa gagggagtcg ctattgattt caacggtagc aggtacatac agaggactcc
    14101 tacctcagat atactgcaat atcatcgtgt gcaaaaaacc tctgagattt ttctcaaagg
    14161 ttctgatttt gctaatttct gttctcaacc gctgcagtaa caaaggcagt gtagagttct
    14221 tctggtcggt ttggacggct tgacagttca gggtgatact gacaagctac aaagaattta
    14281 ttttcaggaa tttccacgat ttctaccaaa cgattgtctg gagaaactcc tgaaaagaca
    14341 aagcctgctg cctcaaactg ctcacggaag gcgttattaa actcataacg gtgacggtga
    14401 cggcgttgca ccacttcttg attgtgataa gcagcagcag ccttagagcc acgtttcaac
    14461 ttagacggat aaagtcccaa acgaagggtt ccacccatat cctcaatatc aatctgatca
    14521 cgcatgatat caatgatagg gtattttgtt tctggtgcaa gctctgcaga attggcacct
    14581 tcaagaccta aaacgtgacg agcaaactcg atacatgtca actgcattcc caagcagact
    14641 cccaacattg gaacatcatt ttcacgcgca tagcggatgg cttggatttt cccttctgta
    14701 ccacgttgac caaaaccacc tggtacgatg atcccgtctg catcagacaa gagttctgct
    14761 acattctctg ctgtcacatc attggcattg acccaattga ttttaacttc tgcatcattg
    14821 acatagccag agtgtttcaa ggcttcgacc actgagatat aggcatcttg caactccaca
    14881 tacttaccaa caagggaaat cttaacttgt ttcttgaggt tcatgacctt gtccaccatg
    14941 gctgaccatt ctgtcatatc cgctgctggt gcgtctaatt tcaaatgatc acaaacaatt
    15001 tggtccatcc cttgtgcctg caagttcagt ggaatttggt aaagatgttc aacatccaac
    15061 gattcgataa cggcttctgg tgccacatca cagaactggg ccagtttatt tttaattcct
    15121 tgaccagctg gctcttctgt acgaataacc aacatatttg gttggattcc caagccacgc
    15181 aattctttga cagagtgttg ggttggtttg gttttcattt caccagcagc cttgaggtaa
    15241 ggaagcaagg ttgtatggat atacatgaca ttatccgcac ccacatctgc cttcatctga
    15301 cgaagagcct ctaggaatgg caaggactcg atatctccta ctgttccacc aacctctgtg
    15361 ataatgacat cagagtcggt cgttagagcg gcacgcttga ttttttcttt caaagcatct
    15421 gtgatatgag gaatgacttg aacagttgcc ccaaggtatt ctccacggcg ttctttacga
    15481 agaacttcac tgtaaatttt cccagttgtc acgttggaat atttgttgag attgatatcg
    15541 ataaaacgtt catagtgacc caagtccaaa tctgtctcag ctccgtcatc tgtcacaaaa
    15601 acttccccgt gctggtaagg actcatggtt cccggatcaa tattgatata agggtcaaac
    15661 ttttgaatgg ttactttgag accacgattt ttcaagagac ggcctagact cgctgccaca
    15721 atccctttcc caatggacga taccacacca ccagttacaa aaatatattt cgtagacata
    15781 gattcctctt tctaaaatgc tcaaggtctt gttaactacg aggggatata gaaaacaaga
    15841 ccctactaat aagaataatc tgggacgact gcaccagatt cacaactaat actcttcgaa
    15901 aatctcttca aaccgcgtca acgtcgcctt gccgtagata tgtgttcctg actttgtcag
    15961 tcttatctac aacctcaaaa cagtgttttg agcagcctac ggctagtttc ctagcttgct
    16021 ctttgatttt cattgagtat aaaatacaag aagataactt cttgaaaaaa caaaaatagc
    16081 tccctaagaa ctagggagcc ccgacctcta aaagaggtgc ccaaacaata tgatacctaa
    16141 aaataggata attgtcaata gctaactctt attcctcgct ggtttcagcg tcgtcatctg
    16201 aaaactcgtc gtcgtcttcg ttgagatcca catcttctcc caagtcatct ggagcgattt
    16261 cgttgatttc tgcatcataa gcttccactt catttttttc atcatctgga ttttcatcat
    16321 cgtatgaaag agctggatct gcttcgtatg catcttcgtc ttctggatca tctgcattgt
    16381 agtcaatggc atctgaatca ccatccataa aggcattgac acgttttttc ttagcttttg
    16441 gtgctacttc atcgtcgtca ttttcttcaa gagcgatgat ttcttcgtcg atttcgtcca
    16501 caccatacca tgaacgaaga ccccatttgt tgtccccaag tgagatgaag ctaccgtcaa
    16561 agttcaactc tgtgtagaac aaaggcaaag cttcgcggat atcgctgttt gatgttccaa
    16621 ggtagttttg aatttcgttt acaagatcgc taaaatgcat ctcatgatcg cgaccacgaa
    16681 gttccaagat agcacgcgct acctcaatca tagatagttc acttttttct tgcccagcaa
    16741 atacttctaa ttccaaagcg tttctcctca tttatactac tatcgccaga gcgaacagac
    16801 tctgacctca ttttatcatt tactctttat tttacgataa ttttgcggaa tagtcaaagg
    16861 ttaaggggga gaaagtggca ggattagact aattccaata taaaactcct tcctttttct
    16921 gttgctccat tttccacaaa tccaagcgac ttgaaacacc tcctagaagc atgattgtag
    16981 gtgtagattt ccttgactct caattctttc catcctttta ctcgagccaa ttcaatcaaa
    17041 gcacttagaa tcttttttcc aagtcctcga tgttggtaag cggaattccc aatcacaatg
    17101 gggagattat cctgagatag tgtaatatcc ccaattggaa accattctcc cttctccttg
    17161 acttcaatcc aaaaaagctc accatgccga tccaaatagg aatacatggc ttccaaggtc
    17221 gcttgactgt aaggaagctt caccccatct acgaggtaaa ccaagttcac atcctgatac
    17281 caagcaaaag cttcctcaca atgattgacc ttataataag gaacaaaaca caatgcacta
    17341 ccttttcaac aaaagagttg ctgcttgatt aaaaccatca caccagttat accattttgc
    17401 ttcataccca tcttgagcta ggatacgatc ttctaaatca aaaacagagt aaatctttct
    17461 ttcctcgcaa gcttgcgcat agagatgata tagttcatca ccaccatctc tatcccactc
    17521 agcagaaatc gtatcccgac ctgccaataa agcctgataa gccctgtgat gcccatctgt
    17581 aatcagcaaa caatctccaa aggcaagaat actgattgga tcgacttggt ttgtttctgc
    17641 cgactggtaa agcatctgaa tatcttgcaa cttcttttct gataaatata gttgagtcgg
    17701 atgaagatct gctatattga ctttcatttc tttctcctca agggaattcg atactcactt
    17761 ctgtttgcct ttaaatcgcc attggaagcg gagcttgtca tagaagggaa actcgataaa
    17821 caggactccc aagcccacac agagactggc aaagacgtct gatgggtaat gaacccccag
    17881 atagactctt gataccagca cactgactag gtagaggcca aggacgattt gtacgatttt
    17941 tctccagact ggatttttaa ttcgttgact gagaatgaca atcagagtac ctaccatcaa
    18001 agttacagcc agagaatgtc cacttgggaa ggaaaatccc ttctcttcca ccagatgtaa
    18061 gatagctggt cgtgggcgct ggtagatatt tttaaaggtc acgattaaaa gacctgccaa
    18121 agccagattt cccagcatga agaaactttc tatcttccat cgcttacgat aaaagacaaa
    18181 agctgtaatg acaacccaag tgataatcac tgggatatca atcagacgtg tgagggctcg
    18241 aaaaagaata gtcaaataat ctggtaagtc tcctcgaatg gcagtctgaa tcgattggtc
    18301 aaaattgacc aacatttcag ggtaaaattt gaccatatag ccaagaataa cgaaaagtaa
    18361 aagggcaaaa ctgcccttca ttaaaaatgt ttgtttatct ttcatagtgt tttaaggttg
    18421 gtttcaaaag gacgtacaac aaccagaatg aaacggaaaa gattacaccc tcaatcaagt
    18481 taaaaggtaa taccatggtc attaggtagt tggaaagtcc caaaattttt ccaatatcaa
    18541 agttagcaaa cttagcgtac aaaggaacag cataaacata gttgagaacc aacatggcca
    18601 aggttaaacc aacagttcca gctagagagc ctagtaggaa acgaagggtt gtccgttcct
    18661 ttttccaaat caaagcaaat acgatgacaa aaactcccaa agctacgata ttcatcggca
    18721 aaccaatgta agtattcact ccttggctgt taagaagcaa tttcaatagt gagcgaagca
    18781 agagcactcc tagagcagca ggcaaatcca tgaccaccag acccacaagg actggcaaga
    18841 tactaaattc gatcttgagg aaagatgccg ctggtaaaag cggaaagtca aagtacatca
    18901 gcacaaatga gatggctgat aaaattgcaa tggtcgaaag tcgacgtgtg tttgtcataa
    18961 caggttcctc caattttcta taaaatcaga agaagttgga aaggattcct ctatctattc
    19021 tcacttttta tatcccaaaa attccctctt actctattaa agaaaaacaa agcaagtggt
    19081 tacaatccgg ctataaatct atcaaaacag acaaagctat tctttcgtct tctcccatcc
    19141 agactatact gtcggttgtg gaatctcacc acatcagctt gcgctcgcgg acttctttaa
    19201 agagaaggaa aagatcattt cctagttaaa gtcaccgccg gtcgggaatc acaccctgcc
    19261 ctgaagactc ttttatcata acaaaaaacg cttgcaagcg caagcatttt gttcattttc
    19321 attttcattt tttatttcaa tttatccact tcataggtat ggacgagctc aagacctgca
    19381 aagttctgct ggcgaagagc ctcatagaca atcatgcaga cggtattaga cacattgaga
    19441 ctgcggacat gttcatcatt catgggaata cggagagcct tctcaggatg ttctcgcata
    19501 aaatcttcag gtaagccctt gtcttcacgt ccaaagagaa aataatggtc ctcgtcagtc
    19561 gataaatcca cctcagaata gactttttct gcgaatttcg aaatcagata gagttttccc
    19621 ttcatctgag atatgaaatc ttccaaactc tcgtaaaaat aaatctctag cttatcccag
    19681 taatccaatc cagcccgctt catcttgcgg tcatcaatag gaaagcccat aggcttgatg
    19741 atgtggaggg gagaattggt cgcagcgcaa gtacgcgcga tattgcctgt attttgtgga
    19801 atttgaggtt caaataatac aatgtgattt gtcatgactt gcttcctttc accattgcaa
    19861 aaaaatagcc acactgcccg gagtcaagct cagcaaacag cgtggttaag gcatcgttaa
    19921 cttacctcac aacaggtttg aagtaaatca gcgaaactac tttcttagta taacactttc
    19981 agaatcattg tcaatagaaa tgacttgatt ttttcaattt tttcaagcta tttccaaggg
    20041 ttgtaaaatc gtccctgatt ctgcaagata agtagtaaac taactactaa aaacaaggtt
    20101 gccaagagca aggtaatata gtctcctttt ttcaaggcct gataactata ccatgtgcgt
    20161 tttttctctt tcccaaagcg gcgaagctcc atggcagtcg caatggtatc aatgcgttct
    20221 agcgagctaa aaatcaaggg agtaataatg agcagattgc ctttgattcg ttgcataaga
    20281 gaagctttct tggataattc catcccacgc gcttcctgag acatcttgat ggtaaagaat
    20341 tcttcctgca aatctggaat atagcgcaag gttagactga cagaataggc aatcttgtaa
    20401 ggcacaccaa tttgatttaa actggaagca aactgactag ggtgggttgt catcaaaaag
    20461 ataatagcca gaggaatagt gcaaaggtac ttaatagcca aatttagcag ataaaagagc
    20521 tcttgactgg tcagagtgta ggcaccgatt ccctgccaaa tcacacttct ctctccgtaa
    20581 agtccaaccc catactcggg agaaaagaga tagaccatca aaacgtttaa aacggcaaat
    20641 accgtcgcaa aaacggctac aaaggaaaca tctttaaaat ggatttctga caaatagagg
    20701 agaaagaccg aaaagatggc aatcagaaca agcagtctgg tatcatagct aatcatggcc
    20761 gccaatgaca cgagaatgaa aaagaggagt ttcccagcgc ctgacaagcg atgaatcaca
    20821 gtatctctat gctggtaacc gattaattta gcttgcatcc ttctctcctt tctttgtaaa
    20881 atgccgttaa agcaagtgga tccacgtcga gtttcttagc caagttgaag atagaagtct
    20941 cttttaggtt ggcttttact aacagctcag gattgctcaa cagactagct ggatcagtat
    21001 cagcaatcaa ttccccatcc accatgacaa gggctcgatc tgaataatcc agcatcaatt
    21061 gcatatcatg ggtaatcatg acaatggtat gcccttgttg atgcagttct tcgagaaatt
    21121 ccataatctc agtatagttc ttctggtctt gacccgcagt cggttcatct aggaggataa
    21181 tttcagcgcc taagaccaaa attgaggcaa tagtcacacg ttttttctga ccaaatgaca
    21241 gggcagaaat gggccaatta cggaattcat agagaccaca gattttcaag gtttcataga
    21301 ctctcgtttc aatttcctgc tcgtccacac ctcgcaaacg gagtcccaga gccacctcat
    21361 caaaaatcat attggttgaa atcatttgat tgggattttg cagcacatag cctactcgtt
    21421 ccgcccgctc tgcaacagaa tctcctttta tatcctgtcc ttcccaaaga tagcggcctt
    21481 cagtctggat aaagctactc aaggccttgg ctagagttga cttccctgct ccattttttc
    21541 cgacaatggc aatcttttca ccctttttaa tatctaaatg aagagatttt aaaatcggtc
    21601 tatcatcata agaaaacgac acgtcctcta gtctaaagag tgactgcaat tctggggttt
    21661 cttttaccag ttccgtccgc aactgaacct gaccttttga gatagacaag ttatccagat
    21721 ctgctaattg ttcttccttg actaaatcca cacccaattg acggagagtg gtgagataaa
    21781 ggggttcgcg aattccattt tgggtcaaca aatcagtcgc cagtaactgg tcagggctcc
    21841 cattaaaaag gatacgacca tcgtttatca agacaatccg atccacaggg caatgcagaa
    21901 catcctccaa acggtgctcg ataataaggg tcgtcgtccc ctcctcctta tgaatctggt
    21961 caatcaattc gataatatcc tgacctgact tgggatcaag attggcgagt ggctcatcaa
    22021 acaagagaat cggactttca tcaatcaaga caccagccag actgactcgc tgcttttgtc
    22081 cacctgacaa atcctgaggg cgctgatcca gtaaaggaag aaggtccagc ttttcagccc
    22141 atttataaac acgacctttc atctcatcta gggctgtcac atcattttcc agagcaaacg
    22201 ccaaatcttc tgccacagac aagccaataa actgcccatc tgtatcctgc aaaactgtgc
    22261 taaccagatg agacttatca tagatgctca tatcaaaggc tgtttgaccc tttatcaaaa
    22321 attctccata tgtctgaccc ttgtaaatat tgggaataat cccattcaaa cactgaccca
    22381 aggtagattt acctgatcca gatggtccaa caattaagac tttctctccc ttgtaaatgg
    22441 tcaagtctat cccttgcaag gtcggttctt gttgtgtttc ataccggaaa gagaaatcct
    22501 tccactcaat tatagcttct ttcatcttac tctcttcatt cgcttcttag acttctattt
    22561 tatcataaat caagcccttc ttgcagtctc ttctcttaaa atcttagcgc caaaaagatt
    22621 cctatcctag cttacttgcc taactaatct ataaacatcg aaaaagacta gttgcccagc
    22681 cttccccatc attttatact cttcgaaaat ctcttcaaac cacgtcagct tcgccttgcc
    22741 gtaggtatgg ttactgactt cgtcagtttc atctacaacc tcaaaaccat gttttgagct
    22801 gacttcgtca gttctatcca caatttcaaa acactgtttt gagcaacctg cggctaactt
    22861 cctagtttgc tctttgattt tcattgagta ttagtccttt ttcaaacttc ctgcacgagt
    22921 ttgggttcct gcataggcaa gtaagagaag agttcctgca atagctacag atacaccatt
    22981 ggcaattccc gcaacaatcc cttgtgcaaa tactttttct gccgcttctt gataaatcac
    23041 aacatctcca agtggtgcca agacacccca aacaagggca tttgcaagta gttgaatgag
    23101 gttaaaaata agaatatctt tccagtcaaa aacaccattg atcacgcgaa cgtactttct
    23161 aaaaagtccc acaactaaac caaagagtcc gctagcgata atccaagtcc accatagacc
    23221 ataaccagca agagagtcct tgattgcatg accaatcaac ccgacaagca aaccgataat
    23281 cggtccaaaa ataatagaaa gtagcgcttg taccgcatac tgaagctgga tgcttgtatt
    23341 tggaacaggg gttggaatgt tgatcatccc gatgacgaca aagagggcag cgccaattcc
    23401 gacagcaaca acttgtttaa ttgtaaattt aatttccata ctattctcct attttatcct
    23461 tctattttct ttatttcaat ggtccaagat gaaccgacac ctacattata ggccttggca
    23521 aaggaacctt ggttgatagc caaacctaaa cgatagagag agttgatgta aaggatgggt
    23581 tgcccaattc tcacatctgc aaatgatttg ccatagacaa cctgattttg atagaccagc
    23641 atatcagcat gatagatggt cacttcaaaa cgatcaccaa attctggttc cagcttgtaa
    23701 aattcttccc gtgtgataga ggtccaaagc gaaccgaaac gcacatccag aatatcaatg
    23761 gctcccttca ccagatgatc ttctatgatg gtcgctacga ctggaagctc tacaatctgt
    23821 tccacactga gctctggccc tacttcctca aaagtaatgt gaccactggc cagtttagca
    23881 ccagtatagg catagacatc acgaccgtgg aaggtataag aatgctctgt gttttgacgc
    23941 ctattggcca cctcagaaat ctcacgaatg gctacaatgc caacgtgttt cttgataaag
    24001 gaaagcgtcc cattatctgg cgtgacaatg tattgatttt ttgcagtctt ggcaactaca
    24061 ctcttacgtt tcgaaccgac acctggatcg acaaccgata caaacgtcgt tccctcaggc
    24121 cagtaatcca ccgtctgaaa gagacgatag ctcccctcaa aaatattata aggcgtgata
    24181 tcgtgcgtca agtgatggat ttttaaggtt ggagactctt ctaaagccac tccaatcata
    24241 gccgataccg caccatcaac cagaccaaag tctgattgta ataccagtaa attattattc
    24301 attttatctc cttgtatatc ctttatcata ccatatttca gagaaagtcg ctaatagcta
    24361 tttcaattgg ttagggtata gttttacctt atagcgaatt ttcactaaaa gctcttgtta
    24421 ttagctagta ggtgcatttt ttcttgaaaa agggtatgat agttacatca tgaaaaagta
    24481 ggttttatta tgaaaattat ccttgtcgga gggggaaaag ttggttttgc cctctgtcgc
    24541 tccttggttg cagaaaagca tgatgttttg ctgattgagc aagacgaagc tgttctcaat
    24601 catattgtca gtcgctttga tatcattggt atccttggta acggggccga ttttgccatt
    24661 cttgagcaag ccagcgtcca agattgtgat atctttatcg ccctgactga gcacgatgaa
    24721 gtcaacatga ttgcagcagt tctagccaag aaaatgggag ctaaagaaac tatcgttcgg
    24781 gtgcggaacc ctgaatattc taactcttat ttcaaggaaa agaatattct cggtttttct
    24841 cttatcgtta atcctgagct cttggctgcc cgtgctatcg cgaatatcat tgacttcccc
    24901 aacgccctgt ctgtcgaacg ctttgctggt ggacgcgtta gcctcatgga atttgtcgtc
    24961 aagtccacca gcggtctttg ccaaatgccc atttctgatt ttcgtaaaaa atttggtaat
    25021 gtcattgtct gtgcgataga gagggatcat caaattatca ttccaagcgg tgacatgact
    25081 gtacaggata aagatagaat ctttgtcact ggtaaccgtg tcgatatgat actcttccat
    25141 aattatttta aatcacgcgc cgtgaagagc cttctcatcg ttggggcagg tagaattgcc
    25201 tattatctac ttggtattct caaagatagt cgtatcgata caaaagtcat tgaaatcaat
    25261 cctgaaatcg ccagcttctt tagcgagaaa ttcccaaatc tctacatcgt tcaaggagat
    25321 ggaaccgcaa aagatatcct gctggaagaa agtgctcaac actatgatgc cgttgcgact
    25381 ctaacaggag tcgatgagga aaatctgatt acatctatgt tccttgacag ggtaggtgta
    25441 cagaaaaata ttactaaggt caatcgtacc agtctcctcg agattatcaa tgcgcctgat
    25501 ttttcaagta tcatcacacc taaaagcatc gctgtagata cgattatgca ctttattcgt
    25561 ggtcgagtta atgcccagta ttcagacctt caagccatgc accatctagc caatggccaa
    25621 attgaaaccc tgcaattcca tatcaaggaa gccaataaaa tgactgccaa acctctttct
    25681 caactgaaat tgaaaaaagg ggttcttatt gcagccatta ttcgaaaggg caagactatt
    25741 ttcccaactg gggaggatat gttggaagtt ggagacaagc tcctagtaac aaccttgttg
    25801 ccaaacatca ccaagattta tgacttgatt gcgaggtaag aaatgaataa aagtatgatt
    25861 cgttacctcc tttcaaagtt acttttgatt gaagctgttc tcctcttggt tcctgtggct
    25921 atcgctgtct attaccgtga atcgagccaa gtctttacag ccctcttttc gaccataggg
    25981 attctcgtat tgttaggcgg ttcagggagt ttacagaagc caaaaaatca acggatttat
    26041 gccaaggagg gagtcttgat cgttgccctc tgttggatcc tttggtcttt ctttggtggt
    26101 ctcccctttg tcttttctgg gcaaatcccc agccttattg atgccttttt tgagattagt
    26161 tccggcttta cgactactgg agcaagtatt ttgaacgacg tttcagttct cagtcgttcc
    26221 ctcctcttct ggcgaagttt tacccacttg attggaggga tgggagtgct tgtttttgca
    26281 cttgctatta tggacaatgc caaaaatagc cacctagagg tgatgaaggc tgaggttcca
    26341 ggtcctgttt ttggcaaggt tgtatccaaa ctaaaaaaca ctgcccagat tctctatctc
    26401 ctttatctag ctctcttctc cctctttgtc atcatctatt atctagctgg tatgcctctc
    26461 tacgatagtt ttgtcattgc tatggggaca gcgggaactg gaggctttac cgtctataac
    26521 gatggaattg cccactatgg tagctcactg attacctatc tggttagtat aggagttttg
    26581 gtttttgggg taaatttcaa tctctactac taccttatgc tccgtcgggt taaggccttc
    26641 tttggagatg aagagcttcg ggcttacttg gtcatcgtgc tggtttctac aggcttgatt
    26701 agcctcaata ctctctacct ctacccagga ttttccaaaa gctttgaaat ggccttcttc
    26761 caggtttcca acatcattac aacaactggt tttggatatg gagatattac caactggccc
    26821 ctcttctccc agtttatcct cctcttcctc atgacaatcg gtggttctgc tggatcaact
    26881 gcaggtggac tcaagattat tcgaggcctc atcctttcaa aaattgccaa aaatcaaatt
    26941 ttgtccattc tatctcccca ccgtgttttg actctccatg tgaataaaac ggtgattgat
    27001 aaggataccc agcataaaat tctcaagtac tttgtcatct atgctatgat tttgctatcc
    27061 cttatcttta ttgtcagcct agatagcaat gattttctga tcgtgaccag cgctgtcttt
    27121 agctgtttca ataatatcgg gcctattcta ggaaccactt ctagtttctc aatctttagt
    27181 cctatctcaa aaattctcct ctcctttgca atgattgcag gccgcttgga gatttaccca
    27241 atcctccttc tctttatgaa gagaacttgg tctaagagat aaaatacaaa atccctcttt
    27301 ttacaattgt gaaagaggga tttttatatt aaaaaggggg aacgttttta aatccaagcc
    27361 tgtctgtaag caaagtcctt actcaaataa aagatggaaa aacttactac acagcttggt
    27421 aatgctccaa tacaaattgt aaggctttac ttggattctt tgttaaatga atatattcca
    27481 ttcctctggt agcaactatc tgaataccta atctttctgc atccaccttc atctctctat
    27541 aataactccg aacttgtgga gccagaataa ttaaatcata aacacccata atatcataat
    27601 gagctccgta cgctcctgaa ttcgcaatca ctctaacttc tgctaattga gcgccctcgt
    27661 taattgcatt ggctaattgc gcacttgttc cagaccctgc acaaagaacc agtactttca
    27721 actccttact ttttatttca tctaactcac caggcattat ttcacttgtc tcctcctcta
    27781 aaataatatc atttgagctt gcaacatctt ctttcatcag taactgtcta tcatacgctc
    27841 tacagaatgg caaataaatc aatatgtcga caactaaaat caaagataaa aatacaaagg
    27901 agatagattg aaaattcgtt ccaattaaca atcccaaggg accaggaaag gcccaaggta
    27961 actggatata aaatccattc attccaaaga aatcaataaa gacctttcct agaaatacat
    28021 tcactggtgg agtcatcaaa aaaggtacaa aaagataggg attcaaaata actggcatac
    28081 caaatagaag aggttcattc accgcaaata aaacaggagt aattgtagct ttacctaccg
    28141 attttaattg tttagaccgc ataaagaaaa tcaaaataaa tggtacaaca aaggtagccc
    28201 ccgttcctcc gatagcagcg atataatttc cgaaattagg cgttaaagaa tgataaggaa
    28261 actgcccatt tgcaagaagt tgagcattct cttccatatt gctcagttgt aaagctgtaa
    28321 cagcaggtaa gacaatagat ggtccatgaa ttccaacaaa ccaaagcaaa gcgcacataa
    28381 accaaatcaa catcatagca ggatatgatt ctgccccctt aaaaatagga gtcaatagtt
    28441 gttgaaatac ttgggcaaaa ggaacatcta aactaaaccg agatacaata tctaacaaac
    28501 cactaataag taaaacaaaa gaaaaaggaa aaatatctct aaaagcttgt gatatagccc
    28561 caggaacttc cttaggtaaa tgaatagtaa tgtctcgctt aatacagaat cggtaaacat
    28621 ttacagtaat aaaggcactg acaaacgaag ttatcaatcc ttgagatcct aaatagtttg
    28681 tcgacaaact tgtagatccc gtcttctcat caactacaag cgttacagtt aataccagat
    28741 aactacatat ggctgccaac attacagaag tatcatttat tacctttcca ggaggcattt
    28801 ttctattaac atttccagcc aatgactttg caactgtccc tgaaacaata acacccaaaa
    28861 ctcccatggt tagcatatac actttcctca tccaggcaat agctggactc ggtaactcta
    28921 ctccgaaatt tttaggaatc ataataataa tcatcaaaaa gcttgaaaac ataattaaag
    28981 gcatagtagc aatgaatcca tctttaatag ccatcatata attattagta gaaatttttt
    29041 caaatttccc ttgttgcttt tcaatggcag cgactagctt atccataaaa ctcctcctat
    29101 aaaaaattca acctcatatt taaaacatat taaacatcat tcaaatcgct aaccttaatt
    29161 ccgttttagc ccttttaccc aaagagcact tttcttaata tatcgcttct gtgtctcata
    29221 atcaacaaag aaaagaccat atcgcttatt gtagccattc gcccaagaaa attgatcttg
    29281 caaagaccat ataaaatatc cttgaatatt gactccccta tctcgagcct ctaaaacttt
    29341 gtgtaaatgt tgctcaatat aacggattct cttactgtca tcaataatat cattctcgcc
    29401 ctctggctta acctctttaa gggctgtacc attttcagtt aaataaatga caggatgttg
    29461 aggatattct tctttgatac gaagtaacat atcaaataag ccttgaggat aaatattcca
    29521 atcccaatct gttgtcggaa taccaggctt ttttacaaat tcacctagag catttaattt
    29581 aaaagaggac tgtcctttta ttcctgttga attaaattct tgtctatttt cacctttgta
    29641 ttcacgaata aattctgaac gataataatt catcccaaac atcgtattaa gaggtgcagc
    29701 tcttttcata atttctaaat caccatcttc aataataaag ctagaattat tagcttccaa
    29761 tatttgattt aagtgaaaaa gcgtgtcatc actgtagtag cccaaaaaag ttccatctaa
    29821 tagaaattta ttattataaa catcataccg tttagctgcc aaaatatttt ctttttgccc
    29881 atcaatagga tagcctggct ttaaagcatg aatacaacct acctttccct caatccctaa
    29941 ttgatgaaat tcgaggactg caagagcatg cgccaacaac atattatgat tcgcttgaat
    30001 tgcttcagat aattgaaaat gatgattcgg aggaaactga cctcctatat attgacctgc
    30061 agcaagagac atcagttcat tgattgtaaa ccaatgcttg acttctgtaa attcttggaa
    30121 acaaaagcga gcatatcgta tgaaacgatc aatattctct ctattcaacc aatcccctgt
    30181 ttctaacatt ttctgaggcg aatcaaaatg atgtaaagaa acaaacggaa tcacattatg
    30241 ttttaagcag gactgaaaga ctctatggta atactgaaca gccaatatat tcggctcccc
    30301 atctatatca ggaaatatgc gaacccaaga aatagataaa cgcaaagcct gcaaaccatg
    30361 ttctgccgcc aaggctatat cttcttcgta acgataataa aaatcactag ctggatctgg
    30421 taagaacgga ctattttctt gcaaataaac atcccacata tttattcctt tgccatctac
    30481 cctagttgca ccctctactt gataagcagc ggtagcagct cctaataaaa actccttcgg
    30541 taaggcttta acctgtaaat tttccatgac taatcctcat tgcaaaccaa tatgttcttc
    30601 aatctttcga attcgttcat attcatcaat aaaaaacttt acctgatcat acaatagcat
    30661 cgttgtcatc aaagtatctt gaccatgaat catgataaaa ctcacttcaa aattatctcc
    30721 agatgcctcc tccgctaata aattagtctg ttctcgatgg gcagacacta ttgagtcgtt
    30781 tgcagactca accaattctc ttgcctgttc aaaatatcca tctctcgcaa acgccaaagc
    30841 atccatcaaa tctgaccttg catctcctgc gtaagcgaca attgtaaaac caagcatatt
    30901 tatttcttct tttgatttca tctttcttcc tcctcaatct tgatacatct tttacacatc
    30961 attattaaaa tgacttcgct acgatacaaa tagaaagttg accctaaata tcttaaaaat
    31021 ccttaaattt cataatattt aggatcaatc ttctctgaat accttagttc attttctata
    31081 cttataattt ataagtggaa accagcgtaa ttttttgcta cttcaattac acgataaaca
    31141 tccaaattag attggaatag caattcgtga ccacggatat aattcaaaac atttctccat
    31201 tcatcttgag cttgccttgt ttttccagtt gcttgaagat ataaagcctt cgccatctta
    31261 acaacatatt cacgatgata actgagctgt ttccattcat ccttttgact atttaataac
    31321 ttagaaatat tttcctcaat aattggtaaa aaattatcag ctagattgta agctatataa
    31381 taatgattcg ctaaaacatc attttgacgg ctgccaattg cattaaaata atcacatgag
    31441 gaataactag ataatttttc taaatattca acaacagact gccaatttga cccatacaaa
    31501 gcagaaaagt attcttcaat caattcttca taacttcttg tcttcttcca gagcatttgc
    31561 cccataacat aattaggaaa attatgaggg aatccggcac gtaattcttg acacgaaatg
    31621 tacccgttca aatgtaggtt tgaaagataa gatacatctt tgtaaatagt ttgactaatt
    31681 ttcatatagc ctaaatcgcc ataatgagca cgccctaaag gatagtcata tacgaaacta
    31741 tctcctttaa atgttttttg ccactcaaaa agataagata aattttcttc aagagaattc
    31801 ggaagtataa ttttattacg cagataaggt ttaggcgtag gtatggaatt gtcaaaatct
    31861 acatctgcat aactcatttc aaatgttctt gtaatcggtg caaacatcat ggtaaagcgt
    31921 tcaggattat ctaatttttc tttctgaggc gcccataaca actcatggta aagtaggaaa
    31981 caaatctttg tatctaatcc ctcactcgtt aaagccctat ccaattgatt gagaatacga
    32041 atatactgat ccgaaaccaa ttcttgtcta cagttttcgc attcacaaat attattacga
    32101 gcatccgaca accatacatg taagtagtta acatcaggtc ttttcttggc ataatcctta
    32161 ataatttcta ccatcttatc agctacatct ggatttgaaa aatccaggct ggttaaaatc
    32221 ggagccgtat taaacaattc tcgtttcccg tttatttcag cgacataggg tttcttctcc
    32281 tctgaaatac taagacctga ttcccagcca aattttgaag agtaacctaa aacctcacct
    32341 gtccatccat gaccaacacg atgatgaata agacctcttt tttgcaattc tttatccaac
    32401 ctatcactca attcttgtac taattcattt gagaattttt ctttatttag gtatggatta
    32461 aactcatgtt cataccaacg tttcaaaaaa gaatagggat tttcaaactg aatgaaaaaa
    32521 ctgttcatcc caatcttagg tagccaatca atgaaatcta gtatattttc aaatgaatct
    32581 gctccctcta tacatactcc cctatgatag taacttgctg tttcatctat agatagctct
    32641 ttatctaaaa aatcttcaaa tcttaactct ggaataaagt catgtccgcg ccctggtcta
    32701 gtatacacaa caccaaattc atgaaacatt cggtaaattc caataagtaa acctacaatt
    32761 gtattggact caattctccc cttacctttg tttaatgaga tgaaaatatg gtcttttcca
    32821 tcctcttcat tgactaatcc tacaaaaata tccgcttcct tctcctcgac aagttctata
    32881 tcggtattaa atacctgatt catatagtat cttaattcct ctaaggcaaa gctagaataa
    32941 gtatttttct gttgatcaaa tactctgata accatcttat ttccctccaa cagtagcttt
    33001 ttctttttca agattgcgtt tatctgcaat tttgaagaat ggataataaa ttgctacaga
    33061 aaccaaaatc aaaacaactt gtaatagagc tcctcgccaa ctagcccctg tcgcaaggaa
    33121 gcctcctatg ataggtggca ttgtccacgg aaggattaca cctgttgtat agggtactaa
    33181 gcctacagcc attgatacat aggtaatcaa ggcattgatt gtaggagtag caataaacgg
    33241 aatcagcata ataggattta aaaccgttgg aaacgtaaat agaatagctg tattgatatt
    33301 aaagatagac ggtataatag ctagcttacc taatgtttta ttagcacgac tcttactaaa
    33361 taggaagaga caaatcgcaa gaccaatagt cgctccaccg ccaccaataa atacaaataa
    33421 atctttaaac ggtaatgtaa taatgtgttg tagggtttgt cctgcagcca cagcttcttg
    33481 gttttctgta gtaaattgta accaaactgg gtctacaaaa gcatttaaaa cttgtccccc
    33541 attaactcca cagaaccaaa agaatgagtt tacaataaca cataaaatca tacctggaag
    33601 tgttcctgca attaacttaa gcggcgttcc aacaattgca cctaaaagtc cgttgagacc
    33661 tcctgcaact cctgctgctt ccagaccttt taagaccaaa gcccacaaaa caaaagtagt
    33721 aaaaccaggt aaaagagctg aaaatgattt actgaccaca tctgggacac catttggcat
    33781 ttttatcgta attccgcgtt ggataaaaat acgataaatc tccgctgtaa ccaatccaat
    33841 ggtaatcgcc ataaacaaag aagacgcatt caggctagaa aatggtattg cacctccaaa
    33901 taactgcttg acctgctccc catttttatc ataaaccata cttgaaaaac gaggggccat
    33961 caatacaaaa ctggataagg ctatgatccc tgcagacgga ccatctgtac catatccttc
    34021 cgacaacctg taggcaatac cgaaacaagc gaccaaggag ataatcgcta ctgttgactg
    34081 attcatagtt gtcaagatac ttagcaatcc aacactattc agccaatttg taaaagcctc
    34141 ttgaggccaa ctgattagaa taagaaataa agagccgact aaaatcaaag gcattgccat
    34201 cataaatcct tcacgaatag ctttcaaatg ccgttgattg ccaacttttt caccaaacgg
    34261 agcgactttc gtttctaaaa acgttaaaat attgttcatc accggaactc ctttttttat
    34321 tttttataaa ttaaatatac cactaacaga aagcgttgtc aatatatttt ttactgtttt
    34381 tacaatattt ttttctttgt atagaataat aattttaatt gattttttct tatgtttaat
    34441 ataaaataaa ccaaaggagg aaacaaatga ttacaaaaca atcagccttt ttacaaaata
    34501 gagccactat actggaattt ctatatcgaa atccagcaac atcccgtaca gatattgtta
    34561 atgaaacagg acttactcca gcaacaacga ctaacatcat aaaagagcta agcgaacaat
    34621 ccctcatata cgaaactggt gatgaattta gcgagttttc cggatctgga agacgtagaa
    34681 aaactatttc tattacagat aatatcccat ctgttgttgg aggtattgaa ataaacgtct
    34741 taggtatctt tctcagtcta tgtgacttac aagggaaaac tcttttcgag acagaaattt
    34801 tgaatgaaga ttatcctatt tcagaaatca attccaccat taccaatatg ataaaaacag
    34861 ctacaaagta tgtccctttg gagacaaaat tacttggatt tggcttatca atacctggac
    34921 attataacaa agactccgga agcatcatta caaacaaccc catatgggaa tcatttaatt
    34981 tattaaatgt aattaaaaaa ttcgatttcc cttttattgt aaaaaataat atcgattgta
    35041 tggctatagg acaatacctt tttaacccac acaatacccc cgataacttt attttcctac
    35101 acgctggatt aggtatttac acttcctttt tcacaaaaga aaaaatagga gcctctaaaa
    35161 atccttatat cggagaaatt ggacacacca ttgtcgaatt aaatgggcaa tattgtgaat
    35221 gcggaaaaaa aggttgttta caaacatata tttcggatgc ttggttaatc aaacatgccc
    35281 aattattatt taaaaattct caactaactg tactaaaaag ccttgtaaag actgaaaaag
    35341 acattcattt agataccctt ttaacagctt acaacttagg cgactctgct ttacgccaac
    35401 aaattgataa aggagtcaat ttattggcca cttctattgc aaatcttctc ctcatcaatc
    35461 ctgctgataa aatctatatc aacagtcaat tgcttaatta tcaacctttc actcatgaag
    35521 tcagggataa aatccaagat cagctccact tcgttccctt tactcgtaat atagaaattg
    35581 aaattttacc ttacaacaaa catcgtggaa gtataggagc ttgtgcatta gctatcgttg
    35641 cttttttcat agagcatagc aatgtattac aagatattat ttcaccttaa tatattagaa
    35701 atctatagac ctgtttaaat caactataac ctgtagtaaa tatctcgtat ttagacaata
    35761 tgaaaacaag acgacttcca tataggaaac cgccttctcg ctatgctgca tgaaactgta
    35821 aaaatagatg aaagtgatag cggtagtcaa atcaagaggc atcataactc taaaaagtca
    35881 caatatataa gttcatcctc agaaaaatat cattctaatt attgaaatgc ctacatgaaa
    35941 agaaacgtta aatgctcata aaacaaggaa tacaggtatc aaaactgtga caaaacaagt
    36001 ccctaaattt actaaagaca ctactcaact ttacacctgt aaatggttgt tgtataataa
    36061 agttacaaag atgtacgacc acactgttgt aaatcatagt gttcgcgaat atattactga
    36121 tagcatttct acaaatacaa gtaaagggat tggatgagat tcaaacgaaa tatgtcagtg
    36181 ttttggcatt cctagccttc atatcattta aagaattgta tagataaaat ttttcccaat
    36241 acagacactc gtaacaactg cttcattttt ctaccaacat atttaggaac aggataagat
    36301 acaagaggat caatccataa atcagttcta taccaatcta agacaaataa gctaaaaaaa
    36361 cgattgataa taagcaaata gattccaaat tttctctatc tgctcatttt aataaacaat
    36421 actagtgtaa ctatccttcc agtcagaagc ttgtcaaatc acaccgaaaa ttcttctaaa
    36481 atttatctcg ttaggcaatc aagcaaaaac tcaacgatag tacaaacatt atcatacagg
    36541 attgacttcc taaattatat actttagtaa ggtttttgga taagaaaaaa ggttcatttt
    36601 acatttctaa acactctttt ctaatacgag ataatta
//
LOCUS       DAVKEV010000022        35265 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVKEV010000022 DAVKEV010000000
VERSION     DAVKEV010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35265
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.022"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(34..684)
                     /locus_tag="VWZ68_001111"
     CDS             complement(34..684)
                     /locus_tag="VWZ68_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEU9372142.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHICDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            796..1638
                     /locus_tag="VWZ68_001112"
     CDS             796..1638
                     /locus_tag="VWZ68_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU9372143.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            1714..2151
                     /locus_tag="VWZ68_001113"
     CDS             1714..2151
                     /locus_tag="VWZ68_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEU9372144.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            2220..2522
                     /locus_tag="VWZ68_001114"
     CDS             2220..2522
                     /locus_tag="VWZ68_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372145.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(2613..3686)
                     /locus_tag="VWZ68_001115"
     CDS             complement(2613..3686)
                     /locus_tag="VWZ68_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEU9372146.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            3842..4519
                     /locus_tag="VWZ68_001116"
     CDS             3842..4519
                     /locus_tag="VWZ68_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9372147.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            4512..5486
                     /locus_tag="VWZ68_001117"
     CDS             4512..5486
                     /locus_tag="VWZ68_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU9372148.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(5535..7478)
                     /gene="thrS"
                     /locus_tag="VWZ68_001118"
     CDS             complement(5535..7478)
                     /gene="thrS"
                     /locus_tag="VWZ68_001118"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEU9372149.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(7536..7859)
                     /locus_tag="VWZ68_001119"
     CDS             complement(7536..7859)
                     /locus_tag="VWZ68_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU9372150.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            8718..9347
                     /locus_tag="VWZ68_001120"
     CDS             8718..9347
                     /locus_tag="VWZ68_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU9372151.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADEFDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNGKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            9488..9757
                     /gene="rpsO"
                     /locus_tag="VWZ68_001121"
     CDS             9488..9757
                     /gene="rpsO"
                     /locus_tag="VWZ68_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEU9372152.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            10572..11186
                     /locus_tag="VWZ68_001122"
     CDS             10572..11186
                     /locus_tag="VWZ68_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEU9372153.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIQRL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(11479..12228)
                     /locus_tag="VWZ68_001123"
     CDS             complement(11479..12228)
                     /locus_tag="VWZ68_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEU9372154.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            12361..14697
                     /locus_tag="VWZ68_001124"
     CDS             12361..14697
                     /locus_tag="VWZ68_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU9372155.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFGVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            complement(15134..18280)
                     /locus_tag="VWZ68_001125"
     CDS             complement(15134..18280)
                     /locus_tag="VWZ68_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000621470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HEU9372156.1"
                     /translation="MIRTEVTSMTVPDRLPARMRMDGRSIFQQIKNYFDTENKEYFKH
                     PNTYDGISMHLEPNILTSMEHFDLTGFHCECKDFQNQGVCKHWVAMDLYFRSLPQAIQ
                     ERIGKASHKPSFASQLIPTLPSEELQDELVEEKATAPSLALHGQVEIRNHSLAWTLKL
                     QVEQAPRAYVIKDIAHFIFLIFQKEDYFVSQKIGTIRLSLNQFNQASQNLLLYIKKYF
                     IDRNEHSYFNFSYGINPRDYGRYLETPVSYLNDLVPLFQALDVFQYVTSKAEYPLIFL
                     DDSPFIPEEEIFKVVKSNNHYEIINTAYFGFIIQEKLWIRHNHFHIIKEEHRYFLDKL
                     ATWIYHYQENSPLIFSKENKAELMQVCNIISNYVPISIPDELQIHDFIPTFAFSKTRN
                     EIALNMVWSFGEKQVHSKQDLLTLPYTYQASKARKIYHQLLSAGFKEEFHSLSKIKIV
                     DFFLKELPRFRTLGQVQLDESLEKLLVEDPAVIDIFDDESFLSVQFDFSMISEDEVEK
                     AIQALWNQESHYQTKQGKVLVFDDESLKVAQSLQDLRAKFSDGKIKMHKSRAFSLSET
                     FKDNEHVNFSRDFKKMAYDLTHPEEFDIKPYEVKAKLRSYQKEGVKWLSMLDHYHFGG
                     ILADDMGLGKTLQTITLLEANLKPDQKALILAPASLLYNWKEEFRKFVPHKQVEVAYG
                     SKTERIKQIEKSATITITSYPSFRSDLEHYQKQSYDYLILDEAQMIKNSQTKTAQALR
                     EFDVKTCYALSGTPIENRLEEIWSIFQIVLPGLLPSKKEFSKLSPQLVAKLIQPFVLR
                     RKKDEVLTELPELSEHLYSNELSSSQKTLYLAQLRRMQEMVSGASAYEIKRHKIEILA
                     GLTRLRQICNTPALFLEDYKGDSGKMDSLFELLDTIREKGSRPLIFSQFTSMLDLIEQ
                     ELEKKEMSHFKITGQTPSDKRQEMVNLFNQGEKDCFLISLKAGGTGLNLTGADTVILC
                     DLWWNPAVEMQAIGRSHRLGQTKQVDVYRLITLGTIEEKIQELQESKKELFNTVLEGQ
                     ESRSNLSVDDIKEILGVE"
     gene            complement(18469..19707)
                     /locus_tag="VWZ68_001126"
     CDS             complement(18469..19707)
                     /locus_tag="VWZ68_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372157.1"
                     /translation="MHIFLKNRAFRQLTVNEWISSFGDTIFYLAFINYVSSYAFAPLA
                     IFLISLSETIPQVLQLFTGVIADFQKNRISKYISILFIKVLLYSGVTLLLTSTDFSLF
                     SVFFICSMNLISDTIGFLAGYMLTPIYIRLINDDMTEAMGFRQSTSSIVRLIGNLSGG
                     VFLGLFSISTLAFVNVLTFLFAFLGSLLIRNRLKKEEEKIEVPPYVGMSSFFQHLKES
                     MKLLMTMEDVMVLLWILSISQAVLMMVEPVSAILLIHHPFMGLSTGQSLAILIMISLL
                     HVILGGLLSGFLSKKISIRLNIYWSLLMESLIVIDFLRGSFLLILLGSAGDAFSAGVL
                     SPRLQAMIFGIIPEELMGSVQSSINVINLLIPAVLSLALVFLATSAGLEVVAFALIIL
                     LLIAAYLVHQMKNLPNQEEV"
     gene            complement(19709..21145)
                     /locus_tag="VWZ68_001127"
     CDS             complement(19709..21145)
                     /locus_tag="VWZ68_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEU9372158.1"
                     /translation="MTPIKDKVRRVKTPMMVNPDTDLTISSVQQDYFSLALIGFSLLT
                     GDFLSFSKGDQKTGLSAFIKICHLIKIARLDNKITKQQEYWLYDLLMMSQGEKIQKIK
                     QLKQVTSDILLNTPDFSSYFEKYNFKEEAENIKSYLLAKSMDKSGRLFPSNEFGEFVS
                     PVSFQHGFGGVLFFMNKYYVEEDENTVKEWLTKLENYEAANFLHGYSLLFGKAGFLFG
                     ILDRYEKTKERYLIDISKRLVDHLMRVYDNISNLDFALGKSGILLSLMKYCTIFDDKK
                     LANFIKNNINDAYSLLESEDNGDIYSNNFAHGRSGAAYVLKAYTDIFGDSRYQNHLQK
                     FSDGISELLEEKLSSFSKLDNLGLSWCDGVSGLILYLCLIDKERYSEIIYKSQLEMVQ
                     QYEAMGTSFCHGLSSLLQTTIYNKNQKVEQFIKKILLTRSYRNNDRLLQFQGEDGINS
                     YFDFGVGNLGIYWTLLGYTFPFELSKGD"
     gene            complement(21219..21749)
                     /locus_tag="VWZ68_001128"
     CDS             complement(21219..21749)
                     /locus_tag="VWZ68_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HEU9372159.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPSWKMDLFSEEEKRIYFQTTCEVS
                     SKDSAINKYKMEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAHMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LDNIVNIVSYIHKLGI"
     gene            complement(21743..22211)
                     /locus_tag="VWZ68_001129"
                     /pseudo
     CDS             complement(21743..22211)
                     /locus_tag="VWZ68_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22760..23437
                     /locus_tag="VWZ68_001130"
     CDS             22760..23437
                     /locus_tag="VWZ68_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEU9372160.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLCKEVSPVFVQKWQKEAVKLEFALGQIPDKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            23424..24221
                     /locus_tag="VWZ68_001131"
     CDS             23424..24221
                     /locus_tag="VWZ68_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEU9372161.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLEIEETTYLQETGPERGIGRIGNIQPQTFGELAQHVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            24238..25341
                     /locus_tag="VWZ68_001132"
     CDS             24238..25341
                     /locus_tag="VWZ68_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEU9372162.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESNLE
                     ELYQLALQRREESPLIGQLAILNQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            25642..26661
                     /gene="galE"
                     /locus_tag="VWZ68_001133"
     CDS             25642..26661
                     /gene="galE"
                     /locus_tag="VWZ68_001133"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU9372163.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            26663..27598
                     /locus_tag="VWZ68_001134"
     CDS             26663..27598
                     /locus_tag="VWZ68_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9372164.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTNWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSYHRS"
     gene            27773..28417
                     /locus_tag="VWZ68_001135"
     CDS             27773..28417
                     /locus_tag="VWZ68_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372165.1"
                     /translation="MLSKEEYIEEIGLIEKQNYVEVELYPLVADIINPTLKNSLSKRY
                     VFGRRKSNMGQIYYGLSNFPDIVILDKNYQNKARKSIEIEEWKKLRGCVEIKSLKHDL
                     ITEEKIKSTISNSFEHITGEMGQLIGDLLWYKKVIYTNGIEWRFLSLDDKEEIDNTIV
                     QVVNKRIETEEAGNSFDWWKNIKDLSFNYTDIYLSKDCIQEWDEFVKKVKEIEW"
     gene            28456..28557
                     /locus_tag="VWZ68_001136"
                     /pseudo
     CDS             28456..28557
                     /locus_tag="VWZ68_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group 2 glycosyl transferase"
     gene            complement(28608..28814)
                     /locus_tag="VWZ68_001137"
     CDS             complement(28608..28814)
                     /locus_tag="VWZ68_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEU9372166.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDILEAVKNCPTRALIGNQEA"
     gene            28866..29342
                     /locus_tag="VWZ68_001138"
     CDS             28866..29342
                     /locus_tag="VWZ68_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEU9372167.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKGFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMVTGSWFANPGDVIKIK"
     gene            29351..30022
                     /locus_tag="VWZ68_001139"
     CDS             29351..30022
                     /locus_tag="VWZ68_001139"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEU9372168.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDCGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            30153..30491
                     /locus_tag="VWZ68_001140"
     CDS             30153..30491
                     /locus_tag="VWZ68_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEU9372169.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            30494..31123
                     /locus_tag="VWZ68_001141"
     CDS             30494..31123
                     /locus_tag="VWZ68_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEU9372170.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            31363..32514
                     /locus_tag="VWZ68_001142"
     CDS             31363..32514
                     /locus_tag="VWZ68_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9372171.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            32827..33576
                     /gene="truA"
                     /locus_tag="VWZ68_001143"
     CDS             32827..33576
                     /gene="truA"
                     /locus_tag="VWZ68_001143"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEU9372172.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            33566..34339
                     /locus_tag="VWZ68_001144"
     CDS             33566..34339
                     /locus_tag="VWZ68_001144"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU9372173.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            34317..34778
                     /locus_tag="VWZ68_001145"
     CDS             34317..34778
                     /locus_tag="VWZ68_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9372174.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     AIIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            35005..>35265
                     /locus_tag="VWZ68_001146"
     CDS             35005..>35265
                     /locus_tag="VWZ68_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9372175.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFGINNSNLRYMIKLIDR
                     YGIEFVKKGKNRYYSPDLKQEMINKVLHEGWTKDRVSLEYGLP"
BASE COUNT        10338 a         6392 c         7622 g        10913 t
ORIGIN      
        1 aaaactttca gggttggtag gggacttgag aaattagttg attttctcga catagagttg
       61 ttttgcaatg tccatattca cttgtaaatc ctcgtcgtta ctgaggatag tgaaggtatt
      121 gctgaagcca tcaaactgct taacttggag ctggtcacag atgtgaagtg agtgcttgtc
      181 cagataatgg agaatgtcaa aactatcgtg catccgagtc aggcggtagg cgccagcttc
      241 cttgatatca gctagtggga ggttattgat ttcaacgagg agttctccct tggcaggaat
      301 agttcctccg tgggggcagg ttttagggaa acctagcagt ttatctagtc tttccacgaa
      361 caggtcagag acagtgtgtt ccaagacctc agcttcctcg tgaatctggt cacttgtata
      421 gtctaaatga tgaactagaa aaacttcaat caagcggtgc ttacgataga gctcagagac
      481 cagtttgaga ccgaggtcag tcagtagata gccacattcc ttgtccttta ggatgagatt
      541 ttcacttttc attcgtttga tcatttcagt tacggcaggg ggagagactt gcatgcgagc
      601 cgcaatttcc ttgttggtaa tcttatgcag gtctatgcca atttcataaa tacattttag
      661 atagtcttct ttgtttgggg tcattcgttt cctcttgtct aatatcttta tctagtatat
      721 caaaaaaagc tagatttctc tagctgtgac tttttatgtt atacttattg caagagaaaa
      781 aacgaggaga tggatatgac gaaaatagct cttctttcag atattcatgg aaataccacc
      841 gccttggagg ctgttttggc agatgctcgg cagctaggag tggatgaata ctggcttttg
      901 ggagatattc tcatgccagg gacagggcgt agaaggattt tggacttgtt ggatcaacta
      961 ccgattacgg ctagagtttt gggaaactgg gaagacagtc tttggcatgg tgtccgtaag
     1021 gaattggata gtactcgccc tagtcaacgc tatctcttgc gccagtgcca gtatgtttta
     1081 gaggaaattt ccctagaaga aattgaagtg ctccacaatc aacctcttca aattcatcgt
     1141 cagtttgggg atttgacagt gggaattagc catcatctgc ctgataagaa ctgggggcga
     1201 gagttgattc atactggcaa acaagaggag tttgaccgct tggtgactca tcctccctgt
     1261 gatattgctg tttatggaca cattcaccag cagttgcttc gttacgggac tggtgggcaa
     1321 ttgattgtca atccgggttc gattggccaa cctttctttt tggacgctca gctacggaag
     1381 gacttgcggg cccagtatat gattttggag tttgatgaca agggcctggt agatatggac
     1441 ttccgacggg tagattacga tgtggcagct gaattgcagc tggctaaaga cctgagactt
     1501 ccctattttg aggtttacta tgaaagtctg gtcaatggga tccaccatac tcatcatcag
     1561 gaatttttga gagaattggc tcagaaagag ggttgcgatc gggagttaga cgactggttg
     1621 aaaagtggta acgattgaca ttacaactaa aaagggtata ataatagaaa aagaagagta
     1681 gaggcagggt agcctcgtaa aaaggagaag aggatgcaaa ttccaagtag atttaccatt
     1741 gcaactcata tgctgataat cattgccctc gaggggaagg aaagcaaggt gaccagtgat
     1801 tttctggctg ctagtgttgg ggtcaatcct gtcattatca gaaagatctt gtcccagttg
     1861 aagaaggcag agctgatttc agtagcgcgt ggaacgggcg gaacagagat tgtcaaggac
     1921 cttaaggata ttagtctttt agatgtttat caggcggtcg aatgtcttgg taagacaggt
     1981 caactcttca gtttccatga caatccgaat ccaaattgcc ctgtaggagc tcatattcat
     2041 gatgttttgg atcaaaaatt ggagagaatt cagttgacta tggaggcaga acttggtcag
     2101 accagtctag aaaaagtcgt ggccgatgca gagagtcaga tgaaggatta agagggataa
     2161 atgccctctt tttttctttg gataattatg ataaaatgta gctattaaag gagtaagaaa
     2221 tgtatctcgt tatagaaatt gtattagcct ttatagtgtc attttggaag gataatagaa
     2281 gtttgtggaa tccagtatta tttttattat ccctcatttc aagttatttt tatctatcct
     2341 acctttttta taaaaatgga tacgagaatg ttcagttagc tttttatgta tttgcctttg
     2401 tcttacttcc ttttttgctt tttctaagtg gcatcttttt aatctataat ggggtcattt
     2461 tgttgaaacg agagggacgt tccaagcccc attatctctc aatgctcttt gatttttatt
     2521 gactattaga ttctatttaa aaagacttag aatgaacatg aaagtatgta ttctaggtct
     2581 tttgttttgt atacatttaa ttttcaagag tattatctat ttttccatgc atggtaacga
     2641 gtatcaatca ataactgggt aaggcgaccc aaggtttctc tttcttctgg agtgagggat
     2701 tgagcttgga caaagagatg atgaatgtat tcaagcgcct ttaaggaagc caagtcattg
     2761 atagagctaa taccagcatc aagaatagtg ccaaagaaga ggtcgaagta gagctgaagt
     2821 tcttcgtcag ggactgtggc cacccattct ttaaaggttg tgtctacttg ccggctatca
     2881 ctgttggtct tatccagttg aacgaagtgc ttgtcctcaa tctgccaact aaaggtatcg
     2941 tgctgggcga tgccacccag ggcagtactc tgaacgatga tttggtgagc aggaatttcc
     3001 agcatcatac cgataatgga accttgtgga atgaatatct tgcttctatc cattatcctt
     3061 tgataacccg cagtctgtgt caattcttga tggagaccag gtgcatcaaa tgtataaact
     3121 gctgtgatct gattttgcaa actttgctca atttggctag cagcatagat agcgagattt
     3181 cctcccttgg aatgcccagc cagaataacc ttttgcttag gatgatgggc aaaaaagttc
     3241 tttaaatagc gaagggcgtg cttttgagca ggaatttcct tcatataggt caggtggaaa
     3301 tcttccttcc agccaatgat actgtcatct gtcccacgaa agacaatcag ataggtatcg
     3361 aggctgacac gataagtcat agccgcaaat tgcttttgca gttcagggtc gatgtcgttg
     3421 ataaaatggg agagtttgca atttttgaag cgcttgtgtt gagccaattc atctaataat
     3481 tgaaggcgat ttttgctagt aagcatggtg ggctctcttg gaacctgagg tgctagatct
     3541 aaaagacgtt gaggaagtgt ggagaccaga ttatcaaagg agaggtaggt gatttctatt
     3601 aaggttagaa tgtctaactc attcaaggga aggtcgtaat aagaatcata tgcgacatct
     3661 ttcagatagt caaaaatatt ggccataaga gctcctttct ttttatttat cttagcaaat
     3721 ttccctcaaa ttagctagta gcatagcctg tttgtactgg ctaaaaacag gctatttcaa
     3781 attcagtttc agaccatcta gcatggaaaa atctgttata ataatggaaa aggagaagcg
     3841 catgcacaag attttattaa tagaagatga tcaggtcatt cgtcaacaga ttgggaaaat
     3901 gctctctgaa tggggatttg aagtggtcct ggtagaagac tttatggaag ttttgagtct
     3961 atttgttcag tcggaacctc atctggtcct catggatatt ggtttgccct tgtttaatgg
     4021 ttatcactgg tgtcaggaaa tccgcaagat ttccaaggta cctatcatgt ttctttcttc
     4081 gagagaccag gctatggata ttgtcatggc aatcaatatg ggggcggatg actttgtgac
     4141 caagcctttt gaccagcagg ttcttttagc taaggttcag ggcttgttgc gtcgttccta
     4201 tgagtttggg cgtgatgaga gtttgctgga atatgctggt gttatcctca ataccaaatc
     4261 catggattta cattatcaag ggcaagtctt gaatttgacc aagaatgaat tccagatttt
     4321 acgcgtgtta tttgagcatg caggcaacat cgtagcacgt gacgacctga tgcgggaact
     4381 ttggaacagt gactttttca ttgatgataa taccctctct gtcaatgtgg ctcgtttgcg
     4441 taaaaagttg gaggagcagg gattggtagg atttatcgag accaagaaag gaatagggta
     4501 cggattgaag catgcttgat tggaaacaat tttttctagc ctatctgcgc tcccgtagtc
     4561 gtctttttat ctatctgctt tctttggcat ttcttgtctt actctttcag tttttatttg
     4621 ccagtctagg aatttacttc ctctactttt tcttcttgtg ttgctttgta accatattat
     4681 ttttcacttg ggacatattg gtggaaacgc aggtctatcg ccaggaactt ctctatggag
     4741 agagggaagc caagtctcct ttggaaatag ctttagcaga aaaattagaa gcgcgtgaga
     4801 tggaactcta tcagcagagg tcaaaagcag aaagaaaact gacggatttg ctggattact
     4861 ataccttgtg ggtccatcag ataaagaccc ccattgcagc cagtcaactc ttagttgcag
     4921 aagtggtcga ccgccaactg aagcagcaac tagaacagga aattttcaaa atcgactcct
     4981 ataccaacct agttttacag tacctgcgtt tagaaagttt ccatgatgat ttggtcttaa
     5041 agcaggttca aattgaggac ttggtcaagg aaataattcg taaatatgct cttttcttta
     5101 ttcaaaaagg cttaaatgtc aatctacatg accttgataa agaaatcgtg acggataaaa
     5161 agtggctgct agtggttatt gagcaaatca tctcaaacag tctcaagtac accaaggaag
     5221 gtggtctgga gatttatatg gatgaccaag agctttgtat caaagatacg ggaatcggga
     5281 taaaaaacag tgatgtcctc cgagtatttg aacgtggctt ttcaggatac aatggccgtt
     5341 tgacccagca gtcctctgga cttggccttt atctatctaa gaaaatttct gaagaactgg
     5401 ggcaccagat tcgtatcgag tctgaggtcg gaaaaggaac gacagtgcgg attcagtttg
     5461 ctcaagtgaa cttagtcctt gagtaaaaat agatgagaaa aagcctccag attggaggct
     5521 tttatgctag actcttattt ctcaacgcgt gatttgttgg cgatatcagc taggatagct
     5581 tgaacaaaat tatcaactga gacagtttgt gtttcttttt ggccgtagcg acgaacgttg
     5641 actgtttcgt cttccatttc tttgtctcca acaattaatt ggtaaggaat cttgctggtt
     5701 tgtgaagcac gaatcttgaa ctgcattttt tcattgcgct catctacgtc tgcacggaca
     5761 ccgcggtcac ggagtttctt ggccacttcc caagcgtagt ccacgtgttt ttcgttagat
     5821 actgggatga gggttacttg gtgtggtgcc agccatgttg ggaaggcccc cttgtagttc
     5881 tcaatcaaga tagctgtgaa gcgttccata gttgagataa ccccacggtg gatcatgact
     5941 ggacggtgat cttcgccatc agctccgatg tatttgaggt cgaagcgttc tggcaacaag
     6001 aaatcaagtt ggatagtaga aagggtttct tcttttccaa gggcagtttt aatctggata
     6061 tccaattttg gtccgtagaa ggctgcttca ccttcggctt caaagtagtc cacgcccatt
     6121 tcatcaagag ctgcacgaag catggtttgg gcattttccc acatctcatc gttatcaaag
     6181 tacttatgag tatcttgagg gtcacgaaga gagaggcgga agcggtagtc agtcaagttg
     6241 aagtcttcat aaacatcgat aatcaactga agggcacgtt ggaattcttc ttggatttgt
     6301 tctggagtaa cgaataggtg accgtcgttg agtgacattt cacgtacacg ttgaaggcca
     6361 gtgagggcac cagatttttc gtaacggtgc atcataccga tttcagcgat acggattggc
     6421 aattcacggt aagagtgaac atggtgtttg aaaacttgga tgtggtgcgg acagttcatt
     6481 ggacgaagga caaattcttc cccgtcaccc atgtccatgg ttgggaacat gtcttcttgg
     6541 taatgatccc agtgaccaga agtcttgtaa agctcaacag aagcaagtgg tggagtgtag
     6601 acgtgttggt agccagaagc caactctttg tttacgatgt agcgttccaa ttcacgacgg
     6661 atagtcgcac catttggcaa ccagaatggc aaaccttgtc ccacttcttg tgaaatcata
     6721 aagaggtcaa gctctttacc aagtttacgg tggtcacgtt ccttagcttc ttcacgcatt
     6781 tgaaggtagt ttttcaagtc tttcttgtca aaccaagctg taccgtagat acgttgcatc
     6841 atagcgttgt cgctgtttcc acgccagtac gcaccagcta catggagaag gtggaagatt
     6901 tggatacgac ctgttgatgg aacgtgaggt ccacggcaga ggtctacata ttcaccctga
     6961 cgatagatag tcaaaccgcc ttcgtcttct gagtgttctt caatcaattc caacttgtaa
     7021 gggtcatttt tgaagatttc acgtgcctcg tctttagtca cttcttcacg aatagatggg
     7081 aagttttctt tgacgatttt ttgcatttct tcttcgatac gaggaaggtc ttcgttagag
     7141 atttgaccag ctgtgttgtc agtatcgtag tagaaaccat cttcgatggc tggaccaact
     7201 cccaagtgaa tgtctgggaa aagacgacga gctgcttggg cgaacaagtg agctgctgag
     7261 tgacgcaaga ttggaagggc atcttcgtga tcaggtgtca caatttcgat gcttccatct
     7321 tcagtgatag cgcgagtagt gtcgatgagt ttgccgttga atttaccagc caaggctttt
     7381 ttagctaggg aattgctgat agattgggca atttcaaaag ttgttacgcc agattcgaat
     7441 tcacgaacag cgccatctgg gaaagtaatg ttaatcatga tgttctcctt ttttattatt
     7501 tcatagtttc taagcattga ttttttatca gcagactact tccaagtcct aacgttcaat
     7561 tgcttttctt tatcagagag gaagttttcc atttccgtca gaatgtctat atccaaacgt
     7621 tgagaaagtt ctaatagcca ccagatattt tctgaaagtt tttgttccag tgtgtagggt
     7681 gtttcatcat agtagcgtcc ttgctttgtc atcaccagtc gttggaaatt tccaatatca
     7741 ttagataaag ccaagaggtc ttcttctacc gtccacttga aatcatgatg cttaacttcc
     7801 agttcgtgat aagcttgtcg gattgcccaa ctgcgctcca ctaattcttg caactccata
     7861 attagtatcc taataaaaaa atgcgacatc ctcgaaagga cgtcgcaacg tggttccacc
     7921 ttcatttatg tacctcaaaa gagagggaca cctctgatcg gctctaacgt ggccaccgtt
     7981 ttatgttttc ataaaaaact caagagtagt atcagtttag acttcctatg cgtttccagc
     8041 aaccacgcac tctctagtag aaagggacta agtgacttgt ctctatggat tattatagca
     8101 tgattgtgag atttttcaag gattttgtga aagttttttg tttttcatat tttgtagaat
     8161 atgcttgatg ctaataccag aatccatgcc caccagagca actgtttcat agattagcaa
     8221 gtaaattagt ataaactcac caaaggttat gatagtaaag taaaagagca gtccgttacc
     8281 aactaaccat caaagtgaga aacggaaacg gtagctatag agtaacgata caatcaagat
     8341 taccagaggt gtaaagaaga gaagattgtt tatatagtgt aaaggggtca gaaacaacta
     8401 gcaagaacaa ctcataaagt ggccaataaa agaataatat gaccagatag taggggagat
     8461 gggaatagaa tctacgcatg ataatcacct cgttttaaaa aaacagacaa cttagatctc
     8521 ttgctatgat tattatagca tgtttaaaac aagaaagtaa atttgttgac aaagaagatt
     8581 tttcttttca ctagaatcat agttagtttt cttggtagaa atattttgat aataattaag
     8641 caagactatt gatattgatt attaagagtg tcacatttgt tgtaactaaa ataattacaa
     8701 caatagaggt ataaaaaatg aaactagcag ttattgcagc aaatggacaa gcggggaaag
     8761 caattgttga agaagcagtc aaacgaggac atgaagtaac ggctattgtt cgttctgaaa
     8821 acaaaagtca agctgagtct attattaaaa aagatttatt tgagttgaca aaagatgatc
     8881 ttactggatt tgatgctgtt atttcagcgt ttggtgctta tacaccagat acgctaccgc
     8941 tccacagcaa atcaatcgaa ctatttaatc agcttcttgc tggaacacag acacgttttc
     9001 tagttgtagg gggagcagga agtctttata tagatgaaac aaaaacgaca cgacttttag
     9061 atacgtctga ttttcctgaa gaatttaagt cactagcaaa agctcaagcg gatgaatttg
     9121 atcttcttcg tacaaaaaat aatctcaact ggacttttgt cagtcctgct gtagatttta
     9181 ttcccgatgg tgaaaaaaca ggaaactaca ttctagcagg agaaattttt actactaatg
     9241 gaaaaggaat aagccagatt agttatgcag attatgctat tggattggta gatgaacttg
     9301 aaaaaggtca tcatataaaa gaacgtatct ctttacttga aaaataataa ctatgagagt
     9361 attaatgttt gacagaaaat ttaaatcttg gtaaaatagg gattgtcgta aagacaaata
     9421 acttcttctt ggttacaggc atgccaacct gtcactcgga tgaagccaaa taaaaaggag
     9481 aaacatcatg gcaatctcaa aagagaaaaa aaatgaaatc attgcacaat atgcacgtca
     9541 cgaaggtgat acaggttcag tagaggttca agttgctgtc cttacttggg aaatcaacca
     9601 ccttaacgaa cacatcaaac aacacaaaaa agaccacgct acttaccgtg gattgatgaa
     9661 aaaaatcggt cgccgtcgta acttgcttgc atacttgcgt aaaaacgacg ttaaccgtta
     9721 ccgtgagttg atcaactctc taggacttcg tcgctaattc aagatacaaa ggccgtcaaa
     9781 agcacaaagc aaaaatagga aaattgacga agaaacttca gtttctagga gattttatct
     9841 tttttgccaa gtgcttaggc cgtgttcaat tgagcatatc ttgataataa agctactcta
     9901 aattgggtag ctttgttgcg ttgtcacctt acctcgctat actcaagtat aatcttcggt
     9961 tacggttcct agcactgtaa ggtaaaataa actagctttt ctcccttcgt ggagattttt
    10021 ttgtttcact gaaagtttcg tacgatcttc acctcgtccc ctagtctata aacgatttat
    10081 ctagcaagaa tcatgatgct aagggtgtca aaaatccgta tgaaaatagg gaaatgacac
    10141 agtgttcgat gagcacaagg agtttcatct ttttcactag gattttagcc cgggctaaaa
    10201 tcagctctct gacttcagag ggctttttta ttgaggtttt atcggtaaca attttggaga
    10261 ctacaaaaat ctcaaatggt atcagctaat tacaccataa aggtgcgcag ctactcggct
    10321 tttcaagccg agtagctgta tgcaagcccc ctagaagagc ccactcttta caaagtaaag
    10381 tatagtatgt tatactttac atggaagtag tcactgaatt ccagttagaa attactttgt
    10441 aactacgttt tgaggaggag taaaatgctt tcctacgttc gacattaccc actagcgata
    10501 gctaaattaa tgtgtttgtg ctctcctaaa atctgctgat ttattactga ctaatacagg
    10561 aggttttttt tatgggacag acaatcatat ctgctattgg tgtttatatt tccaccagta
    10621 tcgattattt aattatttta attattttat ttgcacagct atcacagaat aaacagaaat
    10681 ggcatattta tgcggggcaa tatctaggca caggcttact tgtaggggcg agtttagttg
    10741 ctgcttatgt cgttaatttc gtgcctgaag aatggatggt tggattgctt ggtttaatcc
    10801 ctatctattt agggattcgc tttgcaattg ttggagaaga tgcggaagaa gaagaggaag
    10861 aaattattca aagattagaa caaagcaagg caaatcaact gttttggaca gttacattgc
    10921 tgacaattgc gtctggcgga gataatttag gtatctatat accttatttt gcttcgttag
    10981 attggtcaca gaccctcgtg gccttgcttg tgtttgtaat cggcataatt atcttttgcg
    11041 agattagtag ggtgttatcc tctattccgt taatattcga gacaattgaa aaatacgagc
    11101 gaatcattgt gcccttagta ttcattctac ttggactata catcatgtat gaaaatggca
    11161 cgatagagac ttttctgatc gtgtagattt ttttgtttca ctaggatttt agcctgagct
    11221 caaatcagct ctctgatttt cagagggctt tttcattgag tataaatgga caatcttaaa
    11281 gttactctat tgtagagtgg cttttgattt gattagggga ttcttataaa tatagtaaaa
    11341 tgaaataaga ataggacaaa atcgatcagg acagtcaaat cgatttctaa aaatgtttta
    11401 gaagtagagg tgtactattc tagttccaat ctactatata aatgaaaacc ttagctgttt
    11461 ggccaaggtt catttcttct atgcaagttc ttctcttttc ttatctgggt tccagatgaa
    11521 gcttgcgata aagctaaaga tgatggttag gatagcgagg ataatagcaa ggatgagggc
    11581 agggatgcgg ataaaccacc agagtggatt tggtttttta tcattgtgcc attgtttcgt
    11641 ttcttcgtcc agacgttgga attctgtttg aatacgattg gcgactgttt caatgccttc
    11701 atcattcatt ttcttgatat ctgagatatc gattggattt ccaaagttca tatcgacacg
    11761 ttcacggcta atcaagccct tcaaagtcat gggaccggtg taggtaaccg gcatgatacg
    11821 gaccttggcc attttggcaa tcagtgctgc gccccccttg acatcgtttg agtggcggct
    11881 accacttgga aacatgatga gagagcggtc actttttttg agaacgttga taggatattt
    11941 gatggctgag gcgctgggat tttcacggtc gatgggaaag gcgccacaca tacgaatcca
    12001 ccaaccaaag atacggttgg taaagagttc tttttttgcc ataaagatga actgttttgg
    12061 cttggtcgca aaggccatat aaacaggatc ccaccaggta cggtgaggcg caactaaaat
    12121 ataattttca tcttgattag gaattttatc agtattatga tagtgagcat tgccattgat
    12181 ggaccataag agcaatacaa ctaatccacg caaataagta taaaacatgc gatctccttc
    12241 gattgttttc ttgttattat tataccttat caaaggaggg ctggcaaact tttcccttga
    12301 ctagatgcat atttgggatg aaattagaat tctgttaaaa aaaatgatat aatagaattt
    12361 atggataaaa ataagattat gggattaacc caaagagaag tcaaggaaag acaggctgag
    12421 ggtttggtca atgactttac cgcatcagcc agtaccagca cttggcaaat cgttaaacga
    12481 aatgtcttta ccctttttaa cgctttgaac tttgccattg ctttggccct tgcctttgtg
    12541 caggcttgga gcaatctggt cttctttgct gttatctgct ttaacgcttt ttctgggatt
    12601 gtgaccgagc tacgagccaa acacatggtg gacaagctca atctcatgac caaggaaaag
    12661 gtcaaaacca tccgtgatgg tcaggaagtt gctcttaatc ctgaagaatt agtgctagga
    12721 gatgtcattc gtttgtctgc aggagagcag attcctagtg atgccttggt tttggaaggc
    12781 tttgcggaag tcaatgaagc catgttaacg ggagaaagtg atttggtgca aaaggaagtt
    12841 gacggcttac ttttgtcagg aagtttccta gccagtgggt cagttttatc tcaagttcac
    12901 catgtcggtg cagacaacta tgctgccaaa ctcatgcttg aggctaagac cgttaaaccc
    12961 atcaactccc gtatcatgaa atcgctggac aagttggctg gttttactgg gaagattatc
    13021 attccctttg gtctggctct cttgctggaa gccttgcttt taaaaggcct gcctctcaag
    13081 tcatctgttg taaactcgtc gacagctctt ttgggaatgt tgcctaaggg aattgccctt
    13141 ttgaccatta cttcgctctt gactgcagtg attaagctag gtttgaaaaa ggtcttggtg
    13201 caggagatgt actctgttga gaccttggcg cgcgtggata tgctctgtct ggacaagacg
    13261 ggcaccatca cccaaggaaa gatgcaggtg gaggctgttc ttccactgac ggaaacttac
    13321 ggtgaagagg ctattgccag catcttgact agctacatgg cccatagtga ggataagaat
    13381 ccaactgccc aagccattcg ccagcgtttt gtgggagatg ttgcttatcc tatgatttcc
    13441 aatcttccct tctcgagcga ccgcaagtgg ggggctatgg agttagaagg cttggggaca
    13501 gttttcttag gggcacctga gatgttgctg gattctgaag tcccagaagc cagggaggcc
    13561 ttggagagag gatcacgtgt cttggtctta gctctcagtc aggagaaatt agaccatcac
    13621 aaaccacaga aaccatctga tattcaggct ctagccttgc tggaaatctt ggaccccatt
    13681 cgagagggag cagcagagac gctggactat ctccgttctc aggaggtggg actcaagatt
    13741 atctctggtg acaatccagt tacggtgtcc agcattgccc agaaggctgg ttttgcggac
    13801 tatcacagct atgtagattg ctcaaaaatc accgatgagg aattgatggc catggcggag
    13861 gagacagcta ttttcggacg tgtttcccct catcaaaaga aactcatcat ccaaacgttg
    13921 aaaaaagcgg gtcatacaac ggctatgaca ggggacgggg ttaatgatat cttggccctt
    13981 cgtgaggcgg attgttctat cgtgatggcg gagggggatc cagcaacccg tcagattgcc
    14041 aatctggttc tcttgaactc agactttaat gatgttcctg agattctctt cgagggtcgt
    14101 cgcgtggtca ataacattgc ccacatcgcc ccgattttct tgataaagac catctattcc
    14161 ttcctgttag cagtcatctg tattgccagt gctttactag gtcggtcaga gtggattttg
    14221 atttttccct tcattccgat ccagattacc atgattgacc agtttgtgga aggtttccca
    14281 ccattcgttc tgacttttga gcgaaatatc aaacctgtcg agccaaactt cctcagaaga
    14341 tccatgcttc gtgccctacc aagtgccctc atggtcgtgt ttggcgttct ttttgtgaaa
    14401 atctttggaa cgagtcaagg ttggtctgag ttagaaatct caactctcct ctattatctc
    14461 ttggggtcaa ttggtttctt atccgtattt agagcctgca tgccattcac tctatggcga
    14521 gtcctattga ttgtctggtc agtaggaggc ttcctagcca cagctctctt cccaagaatt
    14581 caaaaactgc ttgaaattgc aaccttaaca ggacaaacat tacctgttta tggtgtcatg
    14641 atgttggtct ttacagtgat tttcatcctg actagtcgct atcaagctag aaaataaaga
    14701 aagactgcaa tctgtggatt gcagtttttt atacgatgga tctatcgtag atctgatgtg
    14761 caaggcctac gtgtctatta tctatcggtg aacccaagag tgattctcaa gcctgcttgg
    14821 attgaggtaa tagattcaaa tatctgtagt tagactattt gaagtctgat gcaagaaata
    14881 attctcttcg aaaatatctt caaaccaggt ccgttctatc cacaatctca aagcggtact
    14941 ttgagcaact tgtggtcagc tccctagttt gatagtataa aaactgtcag ataaaggggt
    15001 ggcgaaattg tatctaaacg aacagaaacg tgatggtaag gcgtatagag ctcataggat
    15061 ggcaaggaaa gtctagaacc taaaaaagaa ctagataaat ccactaagtg tggttactct
    15121 agttcttttt cgtttattca acacccaaga tttctttaat atcatcaacg ctcagattgc
    15181 ttctgctttc ttgtccttca aggacggtgt tgaagagttc ctttttactt tcttggagtt
    15241 cttgtatttt ttcctctatg gtaccaagtg tgataaggcg atagacatcg acttgtttgg
    15301 tctggccaag gcggtggctt cggccgatgg cttgcatctc aactgctgga ttccaccaga
    15361 ggtcacagag gatgacggta tcagctcctg ttagattcag tcctgttcca cctgctttta
    15421 gggaaatgag gaagcagtct ttttcccctt gattgaaaag attgaccatt tcttgacgtt
    15481 tatctgaagg tgtttgtcct gttattttaa agtgagacat ttcttttttc tctagttctt
    15541 gctcaatgag atcaagcata gaggtgaatt gtgaaaagat aagtggtcgt gacccttttt
    15601 cacgaatggt gtctaggagc tcgaataagc tgtccatttt tccactatcc cctttgtagt
    15661 cttctaaaaa gagagcaggg gtattacaga tttgtctaag tcgggtcagt cctgctaaga
    15721 tttcaatttt atgacgttta atctcatagg cgctggctcc tgaaaccatt tcttgcatgc
    15781 gtcgaagttg agctagatag agcgtttttt gcgaactgct gagttcattg ctgtagaggt
    15841 gctcgctcag ttcaggcaat tctgtcagaa cttcgtcttt tttcctacgc agaacaaaag
    15901 gttgaatcag tttagcaacg agttgaggtg acaattttga aaattccttt ttacttggta
    15961 ggagacctgg taatactatc tggaaaatag accaaatctc ttcgagacgg ttttcaatag
    16021 gagttccaga tagggcatag caggttttga catcaaattc tcttaaagct tgtgctgttt
    16081 tggtctgact attttttatc atctgtgctt catctaggat gaggtagtcg taagactgct
    16141 tttgataatg ttcaaggtca gatcgaaaag atggatagct tgtaatagtg atagtagcag
    16201 atttttcaat ttgtttgata cgctcagttt tgctaccata ggctacttca acctgtttgt
    16261 gaggcacaaa ttttcggaat tcttccttcc aattataaag aaggctggct ggagctagga
    16321 taagagcttt ctggtctggt ttaaggttgg cttccagaag agtgatggtt tgcaaggttt
    16381 tccctagacc catgtcgtct gccaggattc ccccaaaatg ataatgatcc agcatactca
    16441 gccacttgac tccttctttt tgataggagc ggagtttggc cttgacttca taaggcttga
    16501 tatcaaattc ttcagggtgg gtcaggtcat aagccatctt tttgaaatca cgagaaaaat
    16561 tgacatgttc attgtctttg aaggtttcag aaaggctaaa ggcacgagat ttgtgcatct
    16621 tgatttttcc gtctgaaaat ttagcgcgaa gatcttggag actttgagca accttgagac
    16681 tttcatcgtc aaagactaga acctttcctt gcttggtttg gtagtggctt tcttgattcc
    16741 ataaagcttg gatagctttt tcaacctcat cttctgaaat catagaaaaa tcaaactgaa
    16801 ctgaaaggaa gctttcgtcg tcaaaaatgt caatgacagc aggatcttct actaagagtt
    16861 tttcaagcga ttcatctagt tgaacttgac ccagagtacg aaaacggggg agttctttta
    16921 ggaagaaatc aacgattttg attttggaaa gactatgaaa ttcctctttg aaaccagcag
    16981 aaagcagttg atgatagatt tttctagctt tgctagcttg gtaagtatag gggagggtta
    17041 ggagatcttg tttagaatgg acttgttttt ctccaaagga ccacaccata ttaagggcaa
    17101 tttcatttct agtcttggag aaggcaaagg tggggataaa gtcatggatt tgtaattcat
    17161 ctgggatact gataggaaca tagtttgaga tgatattaca gacttgcatg agttcagcct
    17221 tattttcttt tgaaaagata agaggagaat tttcttgata atgatagatc caagtagcta
    17281 atttatccaa aaagtaacgg tgttcttctt tgatgatgtg gaagtgattg tgtcgaatcc
    17341 aaagtttttc ttgaataatg aaaccaaaat aagctgtatt gatgatttca taatggttat
    17401 tagatttgac aactttaaaa atttcctctt ccgggataaa gggactatca tctaagaata
    17461 taagagggta ttcggctttt gaggttacat attggaagac atccaaagct tgaaaaagtg
    17521 ggacgaggtc gtttaaatag ctaacaggag tctctaaata gcgtccgtaa tctctagggt
    17581 taatgccata actgaagttg aaataagaat gttcatttct atcgataaaa tattttttaa
    17641 tatagaggag taggttttgg gatgcttgat taaactgatt caaggataat ctgattgtcc
    17701 cgattttctg tgaaacaaag taatcttcct tttggaaaat gagaaaaatg aagtgagcta
    17761 tatccttgat aacataggca cgaggagctt gttctacctg taattttaag gtccaggcta
    17821 ggctatgatt tcggatttcg acttgtccat gaagggcaag tgaaggcgcc gtagcttttt
    17881 cttctaccag ttcatcttgg agctcttcag atggcaaggt aggaatcagt tggctggcaa
    17941 aacttggttt atgactcgct ttaccaatgc gttcttgaat agcttggggg agactacgaa
    18001 aataaagatc catggcaacc cagtgtttac agactccctg attttggaaa tccttacatt
    18061 cgcaatgaaa gccagtcaaa tcgaagtgct ccatactggt caggatgttg ggctccagat
    18121 gcatggaaat accatcatag gtattggggt gcttaaaata ttccttattt tcagtatcaa
    18181 aatagttttt tatctgttgg aaaatagagc ggccatccat tctcatacga gcaggtagtc
    18241 tatcgggaac cgtcattgaa gtaacctctg ttctaatcat tcttttctct atcttatcag
    18301 aatttatagg aaaagaatag atttatctta cataaattgc atcttgatag ggattggaaa
    18361 catttgtagt tgcaagatag ttgtatgtaa tatcgacaat caattacaag gagattacga
    18421 ttccatagaa actatcaagt gaaaactgac ttatccataa cattctagct aaacttcttc
    18481 ttggtttggt aagtttttca tctggtgaac tagataggct gctataagta gtaaaattat
    18541 aagagcaaaa gcaacaactt ccagaccagc acttgttgca agaaatacga gagcaaggga
    18601 taggacagct gggataagta agttgataac attgatggat gattgaactg atcccattaa
    18661 ctcctcagga atgattccaa aaatcatggc ttgcaagcga ggactcaata ctcctgccga
    18721 gaaagcatca cccgcacttc ctagtaaaat aagtaaaaaa cttccacgta gaaaatctat
    18781 aacaatgaga gactccatca atagactcca ataaatattc aggcgaatag aaattttttt
    18841 agatagaaat ccactcagaa gtccacctaa aataacatga agaaggctta tcattattaa
    18901 aattgccaga ctttgccctg ttgacaaacc cataaaagga tggtgaatca gtagaatcgc
    18961 actgacaggc tctaccatca tcaaaacagc ttgactaatg gacaaaatcc aaagcaagac
    19021 catgacatct tccatagtca tcaataattt cattgactct ttcaaatgct ggaaaaagct
    19081 actcattcct acataaggag gaacttcgat tttttcttcc tcttttttca agcggtttcg
    19141 gataagtaga cttcctagaa aggcaaataa aaaggttaaa acatttacaa aagctagagt
    19201 agaaatgcta aacagtccta aaaatactcc tccgctgaga ttacctatca aacgtacaat
    19261 ggaactcgtg gactgcctaa aacccatagc ctccgtcata tcatcgttta ttagtcgtat
    19321 gtaaatcggt gtcagcatgt atcctgcaag aaaaccaatc gtatctgaaa tcaagttcat
    19381 gctgcaaata aagaaaacag aaaagagaga gaagtcggta cttgtcagga gcaaagtcac
    19441 tccagaataa aggaggacct tgataaagag gatagaaata tacttgctga ttcgattttt
    19501 ttgaaaatca gctataactc cagtaaaaag ttgcaagacc tgtggaatgg tttctgatag
    19561 gctaatcaaa aatatagcta agggagcaaa ggcataagaa gagacataat tgataaaagc
    19621 taagtaaaaa atagtatctc caaaacttga aatccactca tttactgtta gctgacgaaa
    19681 agctcgattt ttaagaaaaa tatgcatatt aatctccttt acttaattca aatgggaatg
    19741 tataaccgag taaagtccaa taaataccca gatttcccac accaaagtca aaataactgt
    19801 ttattccatc ttccccttga aattgtaata atctatcatt attacgataa gaacgagtca
    19861 ataagatttt ttttatgaac tgttcaacct tttgattttt attgtatatt gttgtttgca
    19921 ataaactact taaaccatgg caaaaactag ttcccattgc ttcatattgt tgcaccattt
    19981 caagttgtga tttatagatt atctcagagt atctttcttt atcaatcaaa caaagataca
    20041 atattaatcc tgaaactccg tcacaccaag aaagacctaa attatctaat ttagaaaagc
    20101 ttgaaagttt ctcttctagt aattcagata tcccgtcaga aaatttttgt aaatgatttt
    20161 gatagcgact atctccaaaa atatcagtat aggcttttaa tacataggca gcacctgaac
    20221 gtccgtgagc aaaattatta gaatatatat ctccattatc ctcggattct aataaactat
    20281 atgcatcatt tatattgttc ttgataaaat ttgctagttt tttatcatca aaaatggtac
    20341 aatatttcat caaactgagt aggataccag acttccctaa agcaaaatct aagttactaa
    20401 tattgtcata aacccgcatt aaatgatcga ctaatctctt acttatgtct attaaatatc
    20461 tctcctttgt tttttcatac ctatctagga ttccaaatag gaaacctgct ttcccaaata
    20521 gtagagagta accatgtaaa aaattagctg cttcataatt ttctaatttc gtaagccatt
    20581 ctttaacggt attttcatct tcctcaacat aatatttatt cataaaaaat aaaactcctc
    20641 caaaaccatg ttggaaagaa acaggactta cgaactcacc aaattcattt gacggaaaca
    20701 aacgaccaga tttgtccata gatttagcca gtaagtatga ttttatattc tcagcctcct
    20761 ctttaaaatt atatttttca aaataacttg aaaaatctgg agtatttaaa agaatgtcac
    20821 ttgtaacttg tttcaattgc tttatttttt ggattttttc tccctggctc atcattaata
    20881 aatcgtatag ccagtattct tgttgtttag ttattttatt gtctaatcta gctattttta
    20941 ttagatgaca tatttttata aaggccgata atcctgtttt ttgatcacct tttgaaaagg
    21001 ataaaaaatc acctgttaat aaagaaaatc caattagtgc taaactaaaa taatcttgtt
    21061 gaactgagct gatagttagg tcagtatctg gattaaccat cattggtgtt ttaactcgtc
    21121 ttaccttatc cttgatagga gtcattgtct ccaagtctat taatgttata tcaccttttt
    21181 tggtatatat aaaatttgta ggagctatat ctacaatttt atattcccag tttatggatg
    21241 taacttacta tattcacaat gttatccagt gttttttctc taatatttaa ggagtgttct
    21301 gtttctcgaa taaattcttc aaagtttaac ccgtcaactt gttcctgaac aagaaaataa
    21361 tcatccacga tataaaattc atcagttaaa ttagtagtat aacttttatc ggctaatttt
    21421 tttagcatgt gagcttcatt ttttatatca tcaagagctg tccattctcc ttcagcatca
    21481 taattcacaa aaggtcttga ctgcttgatg attacttttt gcccgtccga ttttctaatt
    21541 gcccgataaa catttccttt atttgatctc ttaataattt tttccatttt gtatttattt
    21601 attgcagagt ccttacttga aacttcacat gtggtttgaa aataaatcct tttttcttct
    21661 tctgaaaata aatccatttt ccagctagga agactaggga aattttgtct cttatcttct
    21721 acatagttct tccttttttc atctagcaat aaatagatga cttttttatt tttttcatca
    21781 taagcttgtt tttttaaaaa agccccatat ctataatgaa ctggagaatg cattccacat
    21841 tgatagtcag atagtatttt tggagcctta aattctgaca gtctattcgt aagattacaa
    21901 atcatactct tagcttcaga ttctgactta ggatatagag ttataaattt gttagcagta
    21961 gggctcattt ccctagggga attaattttt tttaattcct ctaaattttt aacaacttta
    22021 aagctacaat tatttagttg ggatagttta tacacaatct taaaaatatt tacagcgtct
    22081 tttatttggg agcttatgtg tattttccac ccttgtgcag gcatcttatc tgataaataa
    22141 tagtaattcc aaatatcacc ctgttggaaa tttttatcac attttaaaca ttctttctct
    22201 aataaatcca taacaaactc ctaattatta aaataggcta gagacacagc actagcctat
    22261 tccgtaagta aagctactta ttttatataa aatataacta gcgacctgta attaaacaag
    22321 taaaagaaca atacttaggg agacctgtga caatgatatc ttcctctgga agtagttcta
    22381 attcaaacaa tgtttgttcc atgactgtat cctcctgtta tgataaattc cagaaagcat
    22441 agagcaaatt cgtggttcgt ctgactaaat ttcttatctg aacaccacct tcaaatacaa
    22501 attttagtca aacttttatt ttttctaact ttctaattat attctaccat gtgtttttat
    22561 atgtcaagaa ttttctgaat aaactgttta ttttttattt tttgacattt ttgcaaattg
    22621 tttaaaatct ttcaattgga ttcacttatt actttaggac attgaaactt ctttcgccag
    22681 aggtgcttat attactggga agttgaagat tgaaatgtgg tataataaga ggtaatagag
    22741 ttttggaaag tgagagaaga tgatttcaaa gagattagaa ttggtagctt cctttgtgtc
    22801 acagggggct attttactag atgtgggaag tgaccatgct tatctgccta tcgagttggt
    22861 tgagagaggc caaatcaaaa gcgctattgc aggtgaggtg gtggaaggtc cctatcagtc
    22921 tgcggttaaa aatgttgagg ctcacggcct aaaggagaaa atccaagtcc gtttagccaa
    22981 tggcttggca gcttttgaag agactgacca agtgtctgtc attaccattg ctggcatggg
    23041 tggtcgtttg attgctagga ttttagaaga aggtttgggg aagttagcta atgtagagcg
    23101 tttgatcctc cagcccaata atcgtgaaga cgacttgcgt atctggctac aggatcatgg
    23161 attccagatt gtagcagaaa gcatcttaga agaagctgga aagttttatg agattttggt
    23221 ggtggaagca ggacaaatga agctatcagc cagtgatgtt cgctttggac cgttcttgtg
    23281 caaagaggtc agtccagtct ttgtccaaaa atggcaaaaa gaagctgtta agctagagtt
    23341 tgccctcgga caaatcccag acaaaaatct ggaagaacgt caagttctag tagataagat
    23401 tcaagccatc aaggaggtgc tccatgttag caagtgaagt gatccaagct tatgaagcct
    23461 tttgccctca ggaattttct atggagggag acagccgtgg tctgcaaatt ggcactttag
    23521 acaagggtat ccaaagggtc atggttgccc tcgatattcg tgaagagaca gtggcagagg
    23581 ccattgaaaa gggtgtggac ttgattatcg tcaagcacgc gcctatcttt cgtcctatca
    23641 aggacttgct tgccagccgt ccgcaaaatc agatttacat cgacctgatt aagcatgaca
    23701 tcgcagttta tgtcagccat accaatattg atatcgttga aaatgggctc aatgactggt
    23761 tttgtcagat gctagaaatc gaggagacga cttatctgca ggaaacaggt ccagaacgtg
    23821 gaattggacg tattgggaat attcagcctc agacctttgg agaattggcc caacatgtca
    23881 agcaagtctt tgacctagat agccttcgaa tggtgcatta tcaagagaat gatttgcaga
    23941 agcctatttc aagagtagca atttgtggtg gaagcgggca gtctttctat aaggatgctt
    24001 tggcaaaggg ggcagatgtc tatatcactg gtgatatcta ctaccatact gctcaggata
    24061 tgctgtctga tggcttgtta gcattggatc caggtcacta tatcgaagtg ctttttgtgg
    24121 aaaaaatcgc agcactcctt actcaatgga aagagaaaaa aggctgggaa ctagagattt
    24181 tacctagtca agcatcgacc aatcctttcc gtcatatcta gttagaaagt gaagacaatg
    24241 aaaaaagttg ccattattgg agcaggaatt gtgggagcaa cagctgccta ctacctctcg
    24301 agagaaagtg acctagaggt gaccgttttt gaccatgagc aaggtcaagc caccaaggcc
    24361 gcagcaggaa ttatcagtcc ttggttttcc aaacgccgta ataaagcctg gtacaagatg
    24421 gcgcgcttgg gggctgattt ttatgtggat ttattagctg atttagagaa atcaggacaa
    24481 gaaatcgact tttaccagcg ttcgggagtc tttctcttga aaaaggatga atccaatttg
    24541 gaagaacttt atcaactggc cctccagcgc agagaagaat ctcccttgat agggcaatta
    24601 gccattctga accaagcctc agctaatgaa ttattccctg gtttgcaggg atttgaccgc
    24661 ctgctctatg cttctggtgg agcgagagta gatggccaac tcttggtaac tcgtctgcta
    24721 gaagccagtc atgtcaagct ggtcaaagaa aaagtgactc tgacaccgtt agcatcaggc
    24781 taccagattg gtgaagagga gtttgagcag gttattttgg cgacgggagc ttggttgggg
    24841 gacatgttag aacccttggg ttatgaagta gatgttcgtc ctcaaaaagg acaactacga
    24901 gattatcagc tggtccaaga tatggaagct taccctgttg tcatgccaga aggggagtgg
    24961 gatttgattc cttttgcagg tgggaaattg tccttaggcg ctacccacga aaatgacatg
    25021 ggatttgatt tgacggtaga tgaaaccttg ctccaacaaa tggaggaggc caccttgact
    25081 cactatctga ttttggctga agctacttca aaatctgagc gtgttggaat ccgtgcctac
    25141 accagtgatt tctctccttt ctttgggcag gtgcctgact taactggtgt ctatgcagcc
    25201 agtggattag gttcatcagg cctcacaact ggtcctatta ttggttacca tttagctcaa
    25261 ctgatccaag acaaggagtt gaccttggac cctgaaaact acccaattga aaactatgtc
    25321 aaacgagtaa aaagcgaata atactcaatg aaaatcaaag aacaaactag gtaactagcc
    25381 gcgggttact caaagcactg ctttgaggtt gtggatagaa ctgacgaagt cagctcaaaa
    25441 cactgttttg aggttgtaga tagaactgac gaagtcagta accataccca tggcaaggcg
    25501 acgttgacgt ggtttgaatt ggattttcga agagtataag cattttactg aaattttatc
    25561 aggtagttta ggatggcaaa tgacattccc tgtcaaaaat ggtaaaataa gaaaaaataa
    25621 tctgagaatc gaggaaaaaa gatgcaagaa aagattttgg taactggtgg tgccggtttt
    25681 attggaaccc acactgttat tgaattgatc caagcaggcc atcaagttgt tgtggtggat
    25741 aatcttgtca atagcaatcg taagagttta gaagttgttg aaagaattac aggagttgag
    25801 attcctttct atgaggcaga tattcgtgac acagctaccc tcagagatat tttcaagcag
    25861 gaagaaccga ctggtgtcat tcactttgct ggtttgaagg ctgttggcga atcaacacgt
    25921 atccctcttg cctactatga caacaatatc gctggaactg tcagcctttt gaaagccatg
    25981 gaagaaaaca actgtaaaaa catcatcttc agttcttctg cgacagttta cggggatccg
    26041 cacacagtgc ccatcttgga agatttccca ctttcagtga ccaacccata cggtcgtacc
    26101 aagctcatgc tagaggaaat tttgaccgat atttacaaag cagactcaga atggaatgtt
    26161 gtcttgcttc gttactttaa cccaatcgga gcccatgaga gtggtgattt gggagaaaat
    26221 ccaaacggta ttccaaacaa tctcttgcca tatgtgactc aagtagccgt tggaaaatta
    26281 gagcaagtgc aagtgtttgg agacgattac gatacggaag atggaacagg tgttcgtgac
    26341 tatatccacg ttgtcgattt ggctaagggt cacgttgcag ctttgaaaaa aatccaaaaa
    26401 ggttcaggac taaacgttta taaccttgga actggtaaag gttactcagt tcttgaaatt
    26461 atccaaaaca tggaaaaagc ggtgggacgt cctattcctt accgtatcgt agaacgtcgc
    26521 ccaggtgata tcgctgcctg ctactcagac ccagcaaaag ctaaagcaga actcggttgg
    26581 gaagcagaac tcgacatcac ccaaatgtgt gaagacgcat ggcgttggca aagcaagcat
    26641 ccaaatggat ttgaagacta agatgatgat ttcaatcatc gtcccttgtt taaacgaaga
    26701 ggaagtactt cctctttttt atcaggctct ggaagcttta cttccagatt tggaaacaga
    26761 aatcgagtat gtctttgtcg atgatggatc aagtgatggg accttggaac tcttaaaggc
    26821 ctatcgggag caaaatccgg cagtccatta tatttctttc tctcgaaatt ttggcaaaga
    26881 agcagccctt tatgcaggct tgcaatatgc gacaggagat ttggtggtgg tgatggatgc
    26941 agacctccaa gatcctccta gtatgttgtt tgagatgaaa aatgtactag acaaaaatgt
    27001 agacttggac tgcgttggga cacggagaac tagtcgggag ggagaaccct tctttcgcag
    27061 tttctgtgct gttctctttt atcgcctcat gcaaaaaatc agcccagtag ctctgccgtc
    27121 gggtgtccgt gattttcgta tgatgagaag gtctgtagtc gatgccattt taagcttgac
    27181 cgagtccaat cgtttttcaa aggggctctt cgcctgggtg ggtttcaaaa cctactattt
    27241 ggactatcca aatgtcgaaa ggcaggctgg caagacaaat tggagtttta ggcaactctt
    27301 tttctactcc attgaaggga ttattaattt ttcagatttt cccttgatta tagcctttgt
    27361 agctggtctc ctatcttgtt ttctttctct gctgatgacc ttttttgttg tggttcggac
    27421 cctcattttg ggcaatccga catctggttg gacctctctg atggctgtta ttctctttct
    27481 tggaggtatt caactcttga ccattgggat tctcggcaag tatatcagta agatttattt
    27541 agaaaccaaa aaaagaccgc tttatcttat caaagaaaaa agttatcata gatcatgaaa
    27601 aagtaggagt tatctagcgc agtcactttt ttgtaattat aattcttttg gtctggaact
    27661 tgagtgattt ttaaaaaaat tagggatttg acatgatata aatgaactat gtggaataaa
    27721 tttactgcaa agacgataac ttaataaata aaaaattcag gagggttatt ttatgctaag
    27781 taaagaggag tatattgaag aaatcgggct tatagagaaa caaaattatg tagaggttga
    27841 actgtatcct ttagttgctg atataattaa tccgacttta aaaaatagtt tatcaaaaag
    27901 atatgtcttc ggaagaagaa agagtaatat ggggcaaata tattatggtc taagtaattt
    27961 tcctgatata gttattttgg ataagaatta tcaaaataaa gccagaaaaa gtatagaaat
    28021 tgaagaatgg aagaaacttc gaggatgcgt ggaaattaag agtttaaagc atgatttaat
    28081 tacagaggaa aaaatcaaat caaccatatc gaacagtttt gaacatataa ctggagagat
    28141 gggacaactt attggagacc ttttatggta taaaaaagta atttatacaa atggaattga
    28201 atggagattt ctaagtttag atgacaagga agagatagat aatacaattg ttcaagtagt
    28261 taacaaaaga atagaaacag aagaagcggg aaattctttt gattggtgga agaatattaa
    28321 agatttatcg ttcaattata cggatatata tttatctaaa gattgtatac aagagtggga
    28381 tgaatttgta aagaaagtaa aggaaataga atggtaggag tctattctca ttgagaaatt
    28441 tagattataa gtcgcagtaa gatttattta gagactaaaa aaagaccact ttatcttatc
    28501 aaagaaaaaa gtgaccttcc tgattttaca gaaaaaaata aagtgaaaag actataattt
    28561 tacatggaaa tgtgctaaac tagagggagt ggattatcgc cattgattta ggcttcctgg
    28621 tttccaatca gggcgcgagt tgggcaattt ttaacagcct ctaagatatc ctgactagga
    28681 gaaatttctt tttccagttg gtcagggtca tcgtaaaaac gcacgattcc attatcgtgg
    28741 taatcaaata aatcagaata agtttggcaa agcccacagg cgatacatcg ttcaggtata
    28801 agtgtgattt tcatgttcat atttatattg taataagaaa agtaaaaaaa aacaaggagt
    28861 aaggtatggc aaaagaaccg tggcaagaag atatctatga tcaagaagaa tcaagagcag
    28921 agcgtcggca tcgaaaccac ggaggggctg ataggatggc taatcgtatt ttgacgatcc
    28981 tagctagtat tttctttgta attgtggtgg tgatggtcat cgttctcatc tatctatcat
    29041 cgggggggag taatcgcaca gcagccttaa aaggctttca tgattctgat gcaagtgtag
    29101 tacaaatctc atcttcaagc agttctcagc ctgagcagag ttcagagcca gaatctactt
    29161 ctagtagttc agaagaagct gctaatcctg aaggaacgat taaagttctc gcaggagaag
    29221 gggaagcagc tattgccgct cgtgcaggaa tctccattgc tcagttagag gccttgaatc
    29281 ctgggcacat ggttacagga tcttggtttg ctaatccagg tgatgttata aaaataaaat
    29341 aggagccgat atgaaaacaa ttcaaattgc tattgatggt cctgcttcca gcggtaagag
    29401 tacggtcgca aagattattg ctaaggattg tggattcacc taccttgata caggagctat
    29461 gtatcgtgca gcgacctata tggctcttaa gaaccaatta ggagttgaag aagtcgaagc
    29521 ccttctagcc ttgttggacc agcatccaat cagctttgga cgttcagaaa ctggagacca
    29581 gcttgttttt gtaggagatg tggatattac ccatcctatc cgtgaaaatg aagtgaccaa
    29641 tcatgtttct gctattgcag caattcctga agtgcgtgag aaactggttt ctctccaaca
    29701 agaaattgcc cagcaaggcg ggattgtcat ggatggtcgc gatattggaa ctgttgtatt
    29761 gccacaagca gaattgaaaa ttttcctagt agcttctgtt gatgagagag cagagcgtcg
    29821 ttacaaggaa aatattgcca agggaattga aacagacctt gaaaccctaa aaaaggaaat
    29881 tgctgcgcgt gactacaagg atagtcatcg tgagacttct cctctcaaac aagcagagga
    29941 tgctgtctac cttgatacaa ctggtttgaa cattcaagaa gtagttgaaa aaatcaaagc
    30001 agaagctgaa aaaagaatgt aaatgtagaa aagccgatag attgatatcg gtttttttct
    30061 aaatttgtca aaatgctgat tttagggtat aatagttgct gttcgagaaa ttttgatttt
    30121 caaagaatag tgaatgatga taaggagaaa ccatgaacaa tttaccaaat tgtccaaaat
    30181 gtaactcaga gtatgtctac gaagacggtg ccctactggt ttgcccagag tgtgctcatg
    30241 agtggaatcc tgctgaagtt gcagaagtag aagaaggtct tgtcgctatc gatgccaacg
    30301 gaaataaatt gactgatggt gatacagtaa ctctcatcaa ggacttgaaa gtaaaaggtg
    30361 cgccaaaaga tttgaaacaa gggacgcgcg tgaaaaatat ccgcatcgta gaaggcgacc
    30421 acaatatcga ctgtaagatt gatggttttg gtgccatgaa acttaaatca gagtttgtga
    30481 ggaagattta agcatgtcaa aacactataa acttgtattt tatagccgta tcttcttgtt
    30541 tctagcggct tttacgggag tttatcttga aattactaag catggtggtt ttgggatgct
    30601 tctctattac acggttctgt ccaacctctt ggtaactatt tttacccttt atcttctaaa
    30661 ggttatgagc cgtgtaggtg aaaattggca aaggccaagt ctcttgcgct taaaaggtgg
    30721 ggtcaccatg agtatcatga ttacctgtgt gatttaccat ttcctcttgg cgcccattgc
    30781 gactaatttc tataccctag aaaatttcct ttgccactat atcgttccca tctggttttt
    30841 agcggatacc ctcttttttg acaaacaggg tcaatacaag atttgggatc cagcagtgtg
    30901 gaccatttta ccctttctgt atatgatgtt tgctcttttt aatggcttgg ttctaaaact
    30961 caatattcca aatgctaagg ataatccttt cccttacttc tttttgaatg tgaacaaggg
    31021 ttggaatgtt gtgtttaagt ggtgtctgat tatctttgtt gcctatatgg tagcaggatt
    31081 tattttctac tttatcaagc aaatcaagag aaagtcatcc taatactctt cgaaaatctc
    31141 ttcaaaccac gtcagcttcc atctgcaacc tcaaaacact gttttgaaca acctgcggct
    31201 agcttcctag tttgctcttt gattttcatt gagtataaga tacaagggat tcattttcga
    31261 atttaagaag gagtctacaa accaatgagg cttcttcttt tcttgcttat ttgataacta
    31321 tcaaaaaagt agaagattaa gagaaatata gaaagagatt tcatgaaaca atttttagaa
    31381 cgggccagca ttttggctct ctccctcgtt ttgattacct ccttttccat ttcgagtgcc
    31441 ctaccagcca tgtttgacta ttatcagggt tattctaagg aacaaattga gctcttggtg
    31501 agcttgcctt cctttggaat catgatgatg ttactgctaa atggtttctt agaaaaaata
    31561 tttcctgagc gcttacagat tagtttgggc ttgctgattt tatcattgag cggtacagct
    31621 cccttctggt accaagccta tccctttgtc tttggaacac ggcttctctt tggtttgggt
    31681 cttgggatga tcaatgccaa ggccatttct attatcagtg aacgctacca aggaaaaagg
    31741 cgaattcaga tgttagggct acgcgcttct gcagaggtcg ttggagcttc tctcattacc
    31801 ttggccgtcg gtcagttgtt ggcctttggt tggacagcta tctttctagc ctatagtgct
    31861 ggatttttgg tgctgcccct ttatctgctc tttgtccctt atggaaaatc aaagaaagaa
    31921 gtcaagaaaa gagcgaagga agcaagtcgt ttaactcgag aaatgaaagg cttgattttt
    31981 accttagcta tcgaagcggc agttgtagtt tgtaccaata cagctattac catccgtatt
    32041 ccaagtttga tggtggaaag aggattgggg gatgcccagt tatctagttt tgttcttagt
    32101 atcatgcagt tgatcgggat tgtggctggg gtgagttttt ctttcttgat ttctatcttt
    32161 aaagagaaac tgctcctctg gtctggtatt acctttggct tggggcaaat cgtgattgcc
    32221 ttgtcttcat ccttgtgggt ggtagtagca ggaagtgttc tggctggatt tgcctatagt
    32281 gtagtcttga cgacggtctt tcaacttgtc tctgaacgaa ttccagctaa actcctcaat
    32341 caagcaactt catttgctgt attaggctgt agtttcggag cctttacgac cccatttgtt
    32401 ctaggtgcaa ttggcttact aactcacaat gggatgttgg tctttagtat cttaggaggt
    32461 tggttgattg taatctctat ctttgtcatg tacctacttc agaagagagc ttaggattga
    32521 ttcctaagtt tttcttttga tactcaatga aaatcaaaga gcatagttga ttgagtttgg
    32581 aatagtacgc tgtagctgct aaaatatttc tagaaattaa tttgactttt ctaatagagt
    32641 tattcatatc ttatttcaat ctactataga aagctagccg caggttgctc aaaatagtgt
    32701 tttgaggttg cagatggaaa ctgacgtggt ttgaagagat tttcgaagag tatgagattt
    32761 ttatacccat acaatatttg ttttaggtcc ttgtttacag actaatttct tgataaaata
    32821 gaggttatga cgagatataa agcaactatt tcctatgatg gttatgcctt tgctggcttt
    32881 cagcgccagt ctcatgcgcg tagcgttcag gaagaaattg aaaaaacctt gaccagatta
    32941 aataaagggc aaaccattac tgttcacggt gctggtagga cagatagtgg ggttcatgcc
    33001 ctgggacagg tcattcattt tgacctgcct tatcagatgg atgaggagaa actccgtttt
    33061 gccttggata cccagtctcc tgaagatatt gatgtgattt cgattgagct tgtggcagat
    33121 gattttcatt gccgttatgc caaacatagc aagacctatg agtttattgt ggatagagga
    33181 cgtcccaaaa atcctatgcg ccgtcactat gccacccact ttccctaccc actcgatgtg
    33241 gaacgaatgc agattgcaat caaaaagcta gagggaaccc atgattttac cggttttaca
    33301 gcctctggga ctagtgtaga ggataaggtt cgcaccatca cagaagctag tttaatagtc
    33361 gatgagacag gacaattttt gacctttacc ttttcaggaa atggtttctt gtataaacag
    33421 attcgcaata tggtggggac tcttctcaaa atcggtaaca accgcatgcc agtagagcag
    33481 attgatctca tcttggagaa gaaggacagg caacttgcag gtcccactgc agcaccaaat
    33541 ggtttgtatt taaaggagat tcgttatgaa gaataatcgt attttagcac tttctggaaa
    33601 tgatattttt agtggtggtg gactgtcagc tgatttggct acctatacct tgaacggctt
    33661 gcatgggttt gtagcagtga cttgtttgac agccttgaca gaaaaaggat ttgaagtctt
    33721 tccaactgat gataccattt ttcaacatga attagatagc ttgcgtgatg tggaatttgg
    33781 gggaattaag attggtcttc tccctactgt cagtgtggct gagaaggcct tggactttat
    33841 caaacaacgc ccaggagtac ctgtggtgtt ggatcctgtc ttggtctgca aggaaacgca
    33901 tgatgtagct gtcagtgagc tctgccaaga gttgattcgc tttttccctt atgtcagtgt
    33961 gattacgcct aatctcccag aagcagaatt attatccggt caggaaatta aaaccttgga
    34021 agacatgaaa actgcagcgc agaaattgca tgatttagga gctccagcag tcattatcaa
    34081 gggaggcaat cgtcttagtc aggacaaggc ggtggatgtc ttttatgatg gacagacctt
    34141 tactatccta gaaaatccag ttatccaagg ccaaaatgct ggtgcaggtt gtacctttgc
    34201 ctctagcatt gccagtcact tgattaaagg tgataaactt ttgccagcag tagaaagctc
    34261 taaggctttc gtttatcgtg ctattgcaca agcagatcag tatggagtaa gacaatatga
    34321 agcaaacaaa aacaactaaa atcgcccttg tatccctatt aaccgccctt tctgtggttc
    34381 taggttattt cttaaaaatc ccaacaccta caggaattct aactctttta gatgctggtg
    34441 tcttctttgc ggccttttac tttggtagtc gtgaaggagc ggtagtcgga ggactagcaa
    34501 gtttcttgat tgacctctta tcaggctacc ctcagtggat gttctttagc ttggtcaacc
    34561 atggcttgca gggatttttc gcaggattta aaggaaaaag tcagtggtta ggccttattt
    34621 tagcaattat tgccatggta ggaggctacg ccttgggttc tactttgatg aatggctggg
    34681 cagcagccct cccagaaatt ctaccaaatt tcatgcaaaa tatggtaggg atgattgtag
    34741 gatttattct tagtcaaagt atcaagaaga ttaagtaata ctcttcgaaa atctcttcaa
    34801 accacgtcag cttccatctg caacctcaaa ccactgtttt gagcagcctg aggctagctt
    34861 tctagtttgc actttgattt tcattgagta taaagaggtt gagtaaaaag tatttcaaat
    34921 aagaaaaacg catagtatca ggtgttgaat gaactgcccc ccaaaagtta gacagaaaaa
    34981 atctaacttt tggggtgttt tattatgaaa ctaacttatg atgataaagt tcagatctat
    35041 gaacttagaa aacaaggata tagcttagag aagctttcaa ataaatttgg gataaacaat
    35101 tctaatctta ggtatatgat taaattgatt gatcgttacg gaatagagtt cgtcaaaaaa
    35161 ggaaaaaatc gttactattc tcctgattta aaacaagaaa tgattaataa agtcttacat
    35221 gaaggctgga ctaaagatag agtttctctt gaatacggtc tccca
//
LOCUS       DAVKEV010000023        33946 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVKEV010000023 DAVKEV010000000
VERSION     DAVKEV010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33946
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.023"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(133..495)
                     /locus_tag="VWZ68_001147"
     CDS             complement(133..495)
                     /locus_tag="VWZ68_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEU9372176.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFGNE"
     gene            503..583
                     /locus_tag="VWZ68_001148"
                     /pseudo
     CDS             503..583
                     /locus_tag="VWZ68_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(990..1148)
                     /locus_tag="VWZ68_001149"
                     /pseudo
     CDS             complement(990..1148)
                     /locus_tag="VWZ68_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(1421..2110)
                     /gene="rplA"
                     /locus_tag="VWZ68_001150"
     CDS             complement(1421..2110)
                     /gene="rplA"
                     /locus_tag="VWZ68_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEU9372177.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2318..2743)
                     /gene="rplK"
                     /locus_tag="VWZ68_001151"
     CDS             complement(2318..2743)
                     /gene="rplK"
                     /locus_tag="VWZ68_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEU9372178.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            2875..3012
                     /locus_tag="VWZ68_001152"
     CDS             2875..3012
                     /locus_tag="VWZ68_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372179.1"
                     /translation="MKIKEQTRKLAAGCSKYSFEVADKTDEVSSKHCFEVVNRTDAVS
                     R"
     gene            complement(3052..3768)
                     /locus_tag="VWZ68_001153"
     CDS             complement(3052..3768)
                     /locus_tag="VWZ68_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEU9372180.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKTKNEDGETKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3771..4241)
                     /locus_tag="VWZ68_001154"
     CDS             complement(3771..4241)
                     /locus_tag="VWZ68_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU9372181.1"
                     /translation="MCLICQRIDLIKKEENPYFVKELETGYLVVGDHQYFEGYSLFLA
                     KEHVSELHHLKKETRLRFLEEMSLVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLKGRGPVWWVPFEEMTAETCQAKPDEIKRLVKRLSSEVDKLLEIKE"
     gene            complement(4243..5280)
                     /locus_tag="VWZ68_001155"
     CDS             complement(4243..5280)
                     /locus_tag="VWZ68_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEU9372182.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREIADYLVKTLEGFGYQPVRTSK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKMDRIGGFPWNMIEGENCTI
                     HVASTGEKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDAKVTSEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRIYKEEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSTLVD"
     gene            complement(5484..6809)
                     /gene="brnQ"
                     /locus_tag="VWZ68_001156"
     CDS             complement(5484..6809)
                     /gene="brnQ"
                     /locus_tag="VWZ68_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEU9372183.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6980..7072)
                     /locus_tag="VWZ68_001157"
     CDS             complement(6980..7072)
                     /locus_tag="VWZ68_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9372184.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(7115..7267)
                     /locus_tag="VWZ68_001158"
     CDS             complement(7115..7267)
                     /locus_tag="VWZ68_001158"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9372185.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LTDSYD"
     gene            complement(7427..8005)
                     /locus_tag="VWZ68_001159"
     CDS             complement(7427..8005)
                     /locus_tag="VWZ68_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEU9372186.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(8059..9459)
                     /gene="pepV"
                     /locus_tag="VWZ68_001160"
     CDS             complement(8059..9459)
                     /gene="pepV"
                     /locus_tag="VWZ68_001160"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEU9372187.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9472..10077)
                     /locus_tag="VWZ68_001161"
     CDS             complement(9472..10077)
                     /locus_tag="VWZ68_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEU9372188.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVCEKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            10248..11048
                     /locus_tag="VWZ68_001162"
     CDS             10248..11048
                     /locus_tag="VWZ68_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9372189.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKESSSQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTYLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSTDSPSN
                     YIVFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(11226..12059)
                     /locus_tag="VWZ68_001163"
     CDS             complement(11226..12059)
                     /locus_tag="VWZ68_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU9372190.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLQGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSKGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRREDNYQRHNLKLLASLIEKHRYVEDVKNFFDF
                     L"
     gene            complement(12049..13893)
                     /gene="uvrC"
                     /locus_tag="VWZ68_001164"
     CDS             complement(12049..13893)
                     /gene="uvrC"
                     /locus_tag="VWZ68_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEU9372191.1"
                     /translation="MNNLIKPKLELLPTSPGCYIYKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNEHYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKNDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVTAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(13932..14633)
                     /locus_tag="VWZ68_001165"
     CDS             complement(13932..14633)
                     /locus_tag="VWZ68_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEU9372192.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWPQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETNE"
     gene            complement(14712..15944)
                     /gene="murN"
                     /locus_tag="VWZ68_001166"
     CDS             complement(14712..15944)
                     /gene="murN"
                     /locus_tag="VWZ68_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEU9372193.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQNKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15949..17169)
                     /gene="murM"
                     /locus_tag="VWZ68_001167"
     CDS             complement(15949..17169)
                     /gene="murM"
                     /locus_tag="VWZ68_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEU9372194.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(17281..18060)
                     /locus_tag="VWZ68_001168"
     CDS             complement(17281..18060)
                     /locus_tag="VWZ68_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU9372195.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(18129..19790)
                     /locus_tag="VWZ68_001169"
     CDS             complement(18129..19790)
                     /locus_tag="VWZ68_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU9372196.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19965..22187)
                     /gene="recJ"
                     /locus_tag="VWZ68_001170"
     CDS             complement(19965..22187)
                     /gene="recJ"
                     /locus_tag="VWZ68_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEU9372197.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22464..23222
                     /locus_tag="VWZ68_001171"
     CDS             22464..23222
                     /locus_tag="VWZ68_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9372198.1"
                     /translation="MVLVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDRMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            23262..24026
                     /locus_tag="VWZ68_001172"
     CDS             23262..24026
                     /locus_tag="VWZ68_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU9372199.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            24039..24716
                     /locus_tag="VWZ68_001173"
     CDS             24039..24716
                     /locus_tag="VWZ68_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9372200.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGATLLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            24726..25385
                     /locus_tag="VWZ68_001174"
     CDS             24726..25385
                     /locus_tag="VWZ68_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9372201.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            25643..26833
                     /locus_tag="VWZ68_001175"
     CDS             25643..26833
                     /locus_tag="VWZ68_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEU9372202.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHSLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(27154..28035)
                     /locus_tag="VWZ68_001176"
     CDS             complement(27154..28035)
                     /locus_tag="VWZ68_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEU9372203.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(28174..29502)
                     /gene="vncS"
                     /locus_tag="VWZ68_001177"
     CDS             complement(28174..29502)
                     /gene="vncS"
                     /locus_tag="VWZ68_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEU9372204.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(29499..30155)
                     /gene="vncR"
                     /locus_tag="VWZ68_001178"
     CDS             complement(29499..30155)
                     /gene="vncR"
                     /locus_tag="VWZ68_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEU9372205.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(30204..30287)
                     /gene="pep27"
                     /locus_tag="VWZ68_001179"
     CDS             complement(30204..30287)
                     /gene="pep27"
                     /locus_tag="VWZ68_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEU9372206.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(30467..31846)
                     /gene="vex3"
                     /locus_tag="VWZ68_001180"
     CDS             complement(30467..31846)
                     /gene="vex3"
                     /locus_tag="VWZ68_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEU9372207.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31898..32545)
                     /gene="vex2"
                     /locus_tag="VWZ68_001181"
     CDS             complement(31898..32545)
                     /gene="vex2"
                     /locus_tag="VWZ68_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEU9372208.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32558..33835)
                     /locus_tag="VWZ68_001182"
     CDS             complement(32558..33835)
                     /locus_tag="VWZ68_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9372209.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9649 a         7712 c         6348 g        10237 t
ORIGIN      
        1 taaactaacc tcctcattat tagcaaggat tctactgatt ataacctaat tcttagacta
       61 cttcaagact aactgtccaa taataatcta cagataaatc atccactctt aataaaattt
      121 tattcaatcc atctactcat tcccaaaagg ttgagattta tctagtaact ctaaaacatt
      181 aatggtaggt agcaacattg cttcactgct atcaattgcc gaaactattg aaacaataga
      241 acgtaaataa tgataaagaa tagcagtacc atttacgtat agaatatcgg tgatattttc
      301 atctatattt atttcaaaat atcctattac agttacagat atttttttca tggcatcttt
      361 gtcaactaaa gaaacactaa gttttacggc tccatgacta taatcatctg tatgaccaac
      421 cttaactatg ggatataata tatcgaaggt aaatgtgaac aaactgatta ggaaatttaa
      481 accaacttct aacaatctgt tatactcaat gaaaaccaaa gagcaaacta ggaaactagc
      541 ctcaggttgc tcaaaacact gttttgaggt tgtagatgga actgacgtag tcagatcaaa
      601 acactgtttt gaggttgtgg atagaactga cgtagtcaga tcaaaacact gttttgaggt
      661 tgtggataga actgacgaag tcagatcaaa acactgtttt gaggttgtgg atagaactga
      721 cgtagtcagc tcaaaacact gttttgaggt tgtggataga actgacgtag tcagctcaaa
      781 acactgtttt gaggttgtgg atagaactga cgtagtcagt aaccatacgc acggcaaggc
      841 gacgttgacg tggtttgaag agattttcga agagtattag aaagctcgat gaactattcc
      901 agattcattc cactaaattt cgaaatcgag taggggataa tctctagccc ctctcacacc
      961 accgtacgtg ccgttcggca tacggcggtt caactaactt ttaacgcatg tcgttcaagg
     1021 taataatcca aacacgaaac cagtccacgt ttttcaagga ctggttttga tatagcacgt
     1081 ttaagtaccg acttctgagc tactaattga tagtggtcgc cccagccaga taccttatcc
     1141 gctatatagg ccttattatc acgttcctgt tcgtagagcc acgatttcgc tatcccttcc
     1201 tctgacgatt cttatttcca gcgtcagact taaaacggtc tatccccaga ccgttttaat
     1261 ccgctacctc acgatagtca gacttgggaa tcgctattgg gttcaccggt agtaggtgcc
     1321 caccgaggac ttacacctca gatatacgac atgcccgtcg tacatcaaaa aaagttgaga
     1381 catagtgtct tcaacttttt tacattactt taactactga ttaaagtgag tttacgtcaa
     1441 ctttgatacc aacaccttga gtagttgtga tagtcaagtt tgttacgtaa gttcctttag
     1501 ctgtagctgg ttttgctttt tggattgttt cgttgaaagc tttaaagttt tcaaccaatt
     1561 tttcagcttc aaatgatact ttaccgatga ttgcttgaac gttacctgca cggtcagcac
     1621 ggtaagtgat tttaccacct ttagactctt caactgcttt agcaacatcc attgttacag
     1681 taccagtttt agggtttggc atcaagttac gtggtccaag gacacgtcca agacgtccaa
     1741 caagagccat catatcaggt gtagcgataa ctacgtcgaa gtccaaccaa ccgtcgttga
     1801 ttttagcaac aaggtcatct tcaccaacaa agtctgcacc agcagctttt gcttcttcag
     1861 cttttgcacc acgtgcgaaa acaagaacac gtgaagtttt accagtaccg tttggcaata
     1921 ccattgctcc acggatttgt tggtcagctt ttttaacgtc gatgttcaag ttgtaagcaa
     1981 cttctacagt tgcatcaaat tttgcaaagt tagtttcttt tgcaagtgct acagcttctt
     2041 ctacactgta tgcttttgtg ctgtcgattt tctcaagagc agcacgaagt tgtttgcttt
     2101 ttttagccat tttctattct ccttgtaagt ggttcaatcg attttcatct cccacgtcac
     2161 ttctcgaaat gatgaagtct tgcgggtttt cagtctacta tttttctctt cctacggcct
     2221 taagctccct tgctgtaccc aagtacaagc ctcagtcact tgcctagtat gaaaagcaac
     2281 taatagactg ctgtgagatt ttctactgtg ttattgatta gtcaacaaca gtgaatccca
     2341 tagaacgagc agtaccttcg atcatacgca ttgcagactc tacgtttgct gcgttcaaat
     2401 ctggcatctt agtttctgca atttcttgta cttgtgcacg agtaactgta gcaactttag
     2461 ttttattagg tgtacctgat cctttttcaa cacctgcagc ttttttcaaa agaacagcag
     2521 ctggtggtgt tttcgtaacg aaagtaaatg atttatcttc gtaaactgag ataacaactg
     2581 gaatgatcat accagcttgg tcagctgtac gagcgttgaa ctcttttgtg aatcccatga
     2641 tgttgatacc agcttgacca agagcaggtc caaccggtgg agctggtgta gctttaccag
     2701 cagggatttg caattttaca agtttttcga cttttttagc catttttaaa tcctcctttg
     2761 tggttttggc ggtaattaga gatttttacc tcccacaagt atgtttttca catacccatc
     2821 cattatacac tatttatctg gaattgcaag agaaaagttt attttttgta ctcaatgaaa
     2881 atcaaagagc aaactaggaa gctagccgca ggctgctcaa agtacagctt tgaggttgca
     2941 gataaaactg acgaagtcag ctcaaaacac tgttttgagg ttgtgaatag aaccgacgca
     3001 gtcagtaggt aaggcgacgc tgacgtggtt tgaagagatt ttcgaagagt attaatcgac
     3061 gtagtctccg ccttcaaagc catagtattc ttccaaactg agaccacttg cagcaatttc
     3121 tttagcttct tttcctacat aacgcaggtg ccattcttca gccatatagc ctgtttcctt
     3181 ttccttgcct ttgagataac ggacaacaaa gccataatca gctgcatgat ccaagagcca
     3241 ttgggctgct ttttcttctg tcaccaaatc accatcagtc ccaatcacat caaaggccaa
     3301 gcctgtctgg tgttcgctat agccaggacg ggcagagtaa cggtcagctg ctgcctttcc
     3361 atcttggttg acataatctt gatagagctt ggtctgagtt tcataacttc taaaaccact
     3421 gtaatgatca ctaataggga aacctgcctc ttgcatcgct ttgatgagtt tgaccaactc
     3481 tgccttggct gttggatttt cccctggatt atagtcttta gacaatggat agtgtttgtt
     3541 ggctacgatg atttcatcgt atttcccttg aatgctgtag taatcacctt tattgaccac
     3601 ttctgctttc ttctgggcag ctccttgaga cttactaccg actgttccat cagctttggc
     3661 tgtctgttct gtcttagttt ctccatcttc attttttgtt ttttcttgtg aacaagctgc
     3721 tagactcaag gctagcaaag ctgtcaagac taggtatctt ttcttcattt ctactccttt
     3781 atttctaata gtttatctac ttctgacgat aaacgtttga ctaatctttt aatctcatcc
     3841 ggttttgctt ggcaggtttc tgctgtcatt tcttcaaagg gaacccacca gactggtcca
     3901 cgacccttga gaccatgacc attcatatca cctgtccgtc gtggaaacag atgccaatga
     3961 agatgagcat cgccatttcc tagcagttcg atattcattt tctcagcagc aaaggccttg
     4021 gcaactgcct cttggactaa actcatttct tctagaaaac ggagtcttgt ctcctttttc
     4081 aaatggtgca attcgctgac atgctccttg gctagaaaga gactatagcc ttcaaaatac
     4141 tggtggtctc caaccacaag atagcctgtt tccaactctt tgacaaagta aggattttct
     4201 tccttcttga tgaggtcaat tctctgacaa ataaggcaca tattagtcca ccaacgtgct
     4261 cttaagataa gcatcgacca ttcgttctgt tgcgatcacc gagtcaatat gggtacgctc
     4321 ataggaatgg ctagactcta taccagcacc gagaagggcg tgtttgactt ctgcccctgc
     4381 agacatagcc gctgaagcgt ccgaaccata aaatggatag atatccagct taaatggaat
     4441 atcttgctct ttcgccaaag ccaccaaatg ttgacggaag tcatagtgat aaggtccaga
     4501 agcatccttg acacagatag acactgtata ttcgtctgtt tgctggtcat ctcccatggc
     4561 tcccatatcc acagccagat attctactac ctgagcagga atgttagagt ttgcaccgtg
     4621 tcccacttct tcaaagactg aaaaagcaaa atgagttgtt acgggcaatt caatcttctc
     4681 ttccttataa atgcgaagga gattgagcaa aatcgccgca ctgaccttgt catccaaatg
     4741 gcgagacttg ataaaacctg tctctgtcac gacagttcgt gggtcaaaac tgataaaatc
     4801 accgacctca atgccaagag cacgagtttc tttttcacta gttactttgg cgtccaaacg
     4861 cacttccata ttgtcttgcg tgcgttctgc agttcctgca tccttataga catggcaaga
     4921 agtttggtgg atgaggatgg ttcctgatac tttttcacct gtgctagcca catgaatggt
     4981 acagttttct ccttcaatca tgttccaagg aaagccaccg atacggtcca ttttgagacg
     5041 gccgtctggt ttgacagcac ggacaatagc accaagcgta tctacatggg cagtcacata
     5101 gcgatgttgc tcatcatttt gacctttaat agttacattg acaccgccct tggatgtgcg
     5161 aaccggctgg taaccaaaac cttctagagt cttaactaaa tagtccgcaa tctcacgagt
     5221 aaagcctgtt ggcgacgcaa tggctgtcag ttctttgata tattctactg tttgattcat
     5281 ttcttcacct cttttgctac ctattataac acatttatca tcggataaaa aaagaaaatc
     5341 actcctgtag acttgactac aaaagtgatt ttatactcaa tgaaaatcaa agagcaaact
     5401 aggaaactag ccgcaggctg tacttgagta cgacaaggcg acgttgacgc ggtttgaatt
     5461 tgattttcga agagtattag tgattattcc atttcaaaaa catcgctttc ttgcttgttt
     5521 ggtagaacca atgagagcaa gattccaaca atggctggca ccaaccatgg gagagatgcc
     5581 ttggcaaaag gaagaacgct aacaagattt gcaagaaact caaccttaaa cgagcttcct
     5641 agtacgcttg caatggcaat aactgtaacc acagcaattg tcaactgcat acctggtttt
     5701 gaaagagcaa caaatttgtt gacaatgaca atcataacga tagcaatcgt gattgggtac
     5761 aagataacca gtactggaat tgagtacttg ataatcgcat caagacccaa attggcaata
     5821 gcaaatccaa tcaaggtaaa ggctgtcgca taaaccttgt agctgatttg tgggaagcgc
     5881 tcattaaaga actcagctgt tgacacaatc aaaccaacag tcgttgtgaa gcaggttacg
     5941 gtaaccatag ctgcaaggaa gagttgagct gttgagccaa agatttcttg agtggcttgt
     6001 gacaagatgt aaacacctgg tgttccaccc ttcatcgctt cagctggtac tgggaaatga
     6061 tttccaagaa aacctaaacc gatgtaaaga gcgctgaagg caagggcaac aacgatacca
     6121 acaacccaaa tagttgaaat gtattctttc ttacttgaaa atccaagttg tttcaaggtt
     6181 tgaactgcga ttacgctaaa ggccactgag gcaagggcgt ccaaggtatt gtaaccttct
     6241 aggaaacctg taccaaaggc agaagcttga taagcagctg aagcagcttg aggacttgtt
     6301 ccaccatatt tgatagctcc cagaacgacc aagataacaa tcaaaattgc aaagactggc
     6361 gttaaaatac gtccaatgcg gtctaagatt tttgatggat taagcgaaat caaataggct
     6421 gccgcaaaat acagaaccgt aaatacaatc aagccaagtc ctttatttgc atccgacaaa
     6481 agggggctaa tccctacttc gtaagctgtt gtagcagtac gtggggtagc aaagaatgga
     6541 ccgattgaca agtaaagaac tgagaggtaa agagtcgcaa accaaggcgc tatcttcgtt
     6601 gaaatctcgt agatataccc tttaggattt agcgttccaa taataagggt caagacggcg
     6661 ataccaacgc ctgaaaagac aaaacctgcg atggcaggaa gaaaatgttc tccagataga
     6721 gcacctagag aaggcggaaa aatcaagttc cccgcaccaa aaaatattcc aaacaggagc
     6781 aaacctgtta gggtaccttt tttagccata aaaatctcct tcatatttat aaaatactga
     6841 cctagtatac cacgattagg agtctgaaaa aagcatcacg aggcaaatat taaatgtttt
     6901 caattttctt aaaaataaga attatctaaa aataaaactc tcctacccag tccacaccaa
     6961 gtaggagaaa tgcaaaattt taaagttctt caaaggctaa catgccaccc tggacattga
     7021 taacattata accttgttct aacaggaatt ggcaagcacg cgccgatctc attccagatt
     7081 tgcaaataat ataatgcaag cgatctttgt ccaattaatc ataactatca gtcaattgac
     7141 taagcggtag gttgtgggca ccttctaaat gaagagctgc aaactcatcc acttctctca
     7201 catccactag agaaagctgg tcgttttggt aaagctggta aaatgcgtca aaggctattt
     7261 ctttcattct ttttcttcta atactcttcg aaaatctctt caaaccacgt cagcgtcgcc
     7321 ttaccgtgcg tatgttaccg acttcgtcag ttttatctgc aacctcaaag ctgtactttg
     7381 agcagcctac gactagcttc ctagtttgct ctttgatttt cattgactat aaaatggttt
     7441 taattctttt tttcaaatct ggcactactt ctgcctcaaa ccaaggattt ttggccatcc
     7501 agatttgatt tcgtggtgat gggtgaacta gcggaaaata ggctggcaga tagtctttat
     7561 agtgtttcac cctctccgtt accttcccac tgattttctc ctgtaaatag taggcttggg
     7621 catattgccc aatcaagagg gttaactgaa tatcaggcaa ttcctgtaag agctgcggat
     7681 gccatttttc tgcaaaacct gtacgaggcg gaagatcacc cgacttgcca tgtcctggaa
     7741 agtagaaatc cataggcaaa acagcaaaat aacctgaatt gtaaaaggta tcttcatcca
     7801 cacctagcca gtcccgcaag cggtcaccac ttttatcttt ccagtaaagg cctgcttctt
     7861 gagttttaag tcccggagcc tgaccgatga tattgatgcg agcagttttt ggcgctgcaa
     7921 agagaggctc aatgccacgc tctgtatagc tggcattctg tgaatccgcc atgatagcct
     7981 gtttgattct ttcgatttga gacatctact ttccctccaa aaagaagtcc aagcataaga
     8041 tctcagactt ctatcgtttt atttgatcaa ttcgtaaata gcttcggcat aaattgctgc
     8101 tgctcggaaa agatcatcca aggcgataaa ttcattggct tggtgcatgg tatcaatcga
     8161 gtctgggaac atagcaccgt aggcaactcc gcgttctagc aagcgaccaa aggttccacc
     8221 accgatgact tgttcatgac ctttaaggcc agtttgtttt tcatagatat tcaacaaggt
     8281 ttgcacaagt ggatcttcca ttggcacata gtgaggcgtg tgaccgtgtt cagacaggct
     8341 aacagaaaca actggcaagt tttcaaggat tgacttgatt tgttctggac ttgttccttt
     8401 tggatagcgg atgttgaggg caatggtatt atcagcactt gtttcatcga agcggaagac
     8461 gccggcattc atagaaagag cacccatctt ttcatccaca tgagcaatct taagattttc
     8521 accctcatga tcgttcaaga gaattttacc tgcgatgtca aggtagtctt tggctggacc
     8581 agcaaagcca aactggctga ggaagagggc aaggtaagtt gcgccattga cacctgaagc
     8641 aggcatagca ccgtgggctg atttaccaat gatcgtcacc ttgtatttgc cagcttcttc
     8701 ttggagttct cctctaagtt tgtgttctgc aacaaaggca tctagtttag cttgcaagtc
     8761 agccaagtca cctgaaacga ctgctgttgc tgattctggt accatatttt cacgtaaacc
     8821 acctgtaaag ctgtgaagac gggcaacacc tgtattttct cctgcaaagt ggaggtattc
     8881 cgtgatattt cctttttcac cattgatgat tggaaattca gcatctggtg agaaaccgaa
     8941 atctggtttg gcaagtccta cgtgctcaaa gtagtagtcc atgtctgccc agcctgattc
     9001 ttcgtctgtt ccaacgatga agcgaacttt cttagaagtt ggaagaccca attctttgat
     9061 gattttcaaa ccatagtaac aagctgttgt aggaccctta tcgtccgaag ccccgcgcgc
     9121 ataaaggcga ccatctttga tagttggtgt gtaagggtct gtgtcccaac cgctaccagc
     9181 aggcaccaca tccatatggg caaagattcc gagaacttct tctccatcac caaactcaaa
     9241 atgtcctgca tagttatcaa cattcttagt tgggtagcca tcgcggtctg cgatttcaag
     9301 gaatttctcc aaggctttta ctggaccagg cccaaatgga tgctgggcat cagccttgct
     9361 gtcatcacgt tctgaattga tttccaaaag gctaaacaag tcagccaaga ggtcttcttt
     9421 gcgtttttct acttctgctg taaaatcaat tgctgtcatt ttttcttctt tctatctttt
     9481 ctcgatgatt tcatctactg gcaagcggta gcttggttcc aatttttcgt ctgtataacc
     9541 cactgtgatc aagagttctg ggcggaaacg gtcttcgatt tccaaaactt cattaacttt
     9601 tgatttgtca aaaccaagga taatattgga accaattcct tggtctgtaa gagcgagaac
     9661 caagttcata gcaaccaaac ctgcattgag tgctaggtag tcgctgactt gttgttcatt
     9721 gtagcgtgca aattcagctg gcaaattttt catgaagtat tgaagttgtt cttctgagaa
     9781 attgttagca ccaccaactc gggcaatctt acgagcgcgt ttggcaaggt ctgtatctgt
     9841 aaatagggca atggttacag gtgctgatga tacctgttca aaattggaac cataagctaa
     9901 ctttgccagt tcagcatttt tctcacatac caccacaaat ttccaaggct ggctgttgtg
     9961 ggcgcttggc gccaaggttg caatttcgat agccgtacgc acatcttttg gatcaacagg
    10021 cttatcagtg aaatgcttgg tcgcatgacg ttttttattt aattcaagaa atttcataat
    10081 cgatttcctt ttctaattct actgcttcca ttctaccata atttgaaaga gcttgcaggg
    10141 atttttcatg attaagtttt tctatcacag acataaaaga tatatattgg tttatcagga
    10201 aagtttctga taaactagca agtactttac atttgaatgg agacagtatg aaaaaattta
    10261 gcctattact agctatccta ccatttttgg ttgcctgtgg gaatcaagct acacccaaag
    10321 agtccagctc tcaaaagaca atcgtccttg ctacagctgg cgatgtgcca ccatttgact
    10381 acgaagacaa gggcaatctg acaggcttcg atatcgaagt cctaaaagca gtggatgaaa
    10441 aactcagcga ttacgagatt caattccaaa gaactgcttg ggagagcatc ttcccaggac
    10501 ttgattctgg tcactatcaa gcagcagcta ataatttgag ttacacaaaa gagcgcgctg
    10561 aaaaatacct ctactcgctt ccaatttcca acaatcccct cgtccttgtc agcaacaaga
    10621 aaaatccttt gacttatctt gaccagatcg ctggtaaaac aacacaagag gataccggaa
    10681 cttctaacgc tcaattcatc aataactgga atcagaaaca cactgataat cccgctacaa
    10741 ttgatttttc tggtgaggat attggtaaac gaatcctaga ccttgctaac ggagagtttg
    10801 atttcctagt ttttgacaag gtatccgttc aaaagattat caaggaccgt ggtttagacc
    10861 tctcagtcgt tgatttacct tctacagata gccccagcaa ctatatcgtt ttctcaagtg
    10921 accaaaaaga gtttaaagag aaatttgata aagcgctcaa agaactctat caagacggaa
    10981 cccttgaaaa actcagcaat acctatctag gtggttctta cctcccagat caatctcagt
    11041 tacaataaca ctcttcgaaa atctcttcaa accacgtcag ctttatctgc aacctcaaag
    11101 ctgtgctttg agcaacctac ggctagcttc ctagtttgct ctttgatttt cattgagtat
    11161 aagatatata aaagcgattg gactaccaat cgtttttagt ttgcattggt tattttagga
    11221 aactcttaca aaaaatcaaa aaaattcttc acatcctcta catacctatg cttttctatt
    11281 aagcttgcta atagtttcag attgtgcctc tgatagttat cttcacgacg tagttcttca
    11341 tacatttcga taaagggaag ccccttggat ttggccaatt ctaactcagc ctcgtaatca
    11401 taagcaactt tacgaaattg gatattgagt aattccccat cttcaacctc tatcacggca
    11461 tactgggcac ggtgattttt taacgcctcc caattaaaat agggcatgcc aatcgaccct
    11521 ggattgatga tttgttgccc tttactgccg tagcgaagca actgcttgtg aacatgacca
    11581 taaactgcca cgtccgtttc cgcatctagc agttggtcaa atttctctgt atcattctca
    11641 actagcaagt caccaccata gtttttgtca ggtaaattat gagagataga aaagcgcaat
    11701 ccgtcaattt ctttcttttc cagcaaaggc aagcttcgta gccagacaat cgttgcagga
    11761 tccattcgct ccatcaaaaa ctgggtcatg cgcattgact ggatttcttt cggatattcc
    11821 aaaccatatt cgccatccaa gacctcaagg acacgatcat cccaattgcc tcgaacactt
    11881 gctgtgatag gaaggtcctt tagcagggcg actaagtcat ttgcgcctgg accaggaaga
    11941 aaaatatctc cctgaagcca atattcactg gccccttgat ttttagcatc tgcaatcact
    12001 gcttctagcg ccgtcgcatt gccatgaaca tctgataaaa ttgcgatttt atggttcatt
    12061 gtggtttcct tccgtttggt aatctactct ttcttctgct acttgaggca aggcttctcc
    12121 ctgcgggttc aactttcttt gcacagcctc tgcaacgact ctaggtaccc caacttcgac
    12181 aatctcatcc acactggctt ccttgatttt ggtcaaagac ttgaaatgct tcataagatt
    12241 ctgcttgcgt ttaggtccca gaccgtcaat cccatccaat tgagatgaga aagaattttt
    12301 ggagcgcagt tggcggtgga aagtgatagc aaagcggtgc acctcatctt ggatgcgttg
    12361 gaggaggaaa aattcctgag aattgcgaga caagtccacc acctcaagcg gatctccaaa
    12421 gagcaattca tgggtttggt gcttatcatt cttttgcagc ccagcaattg gaatatccaa
    12481 gcccagttcc tcttggatga cttgcttagc aatattgact tgaccttgcc ccccatcaat
    12541 cacaatcaaa tctggaggag tcaaagcctc acgctgtact cgaccatagc gtctgcgaat
    12601 gacttctctc atactagcat agtcgtccgg cccaacaacg gtttttatct tgtacttacg
    12661 gtaatctttt ttacttggcc tgccgttaac aaagaccacc atggctgaaa caggactggt
    12721 ccccatgatg ttggagttat cgaaggactc gatgcgaact ggagtcggaa tttggagcaa
    12781 acgtcctaga ttttcaatag ctccttgggt cttttcgact gatttttcta gcagattgaa
    12841 cttctgctct agactaacac gagcattttt tatggctaga ttgaccagct gttttttctc
    12901 tccacgttgg ggtttgagaa tcttggtatc caccaaagcc ttgacagctt cttcgtcaat
    12961 atcctgcgga atcagtacct cattgggaac taggtgagat ttttcttgat agaattgtcc
    13021 cacataggtc aagaaatcct catctggatc attgaagtag gggaagagat tgacatcgcg
    13081 ctcgatgagc ttgccctgac gaacaaagaa aacctgcaca cacatccagc ccttatccac
    13141 atagtagcca aagacatcgc gattttggag atccttagcc atgacccgtt gcttggttcg
    13201 aagtgttcca atggcctgaa tcaggtcacg gtattccgct gcccgttcaa actccatact
    13261 ttgtgctgtt actgccattt tactcttgag atcatcgatg attttgtcat cctgaccttt
    13321 cagaaaatca gacacctcct gggccatgga cttgaaatag gcctcgtcat tcttacagat
    13381 ggtgtgggcc atacattggc cgatatggta gtaaaaacag accttagagg gcgggttggt
    13441 acattttcga aaagggaaaa tcctatctag aagtcgcttg atttcattgg ctgcccccac
    13501 atctggataa gggccaaaat aaagaccacc gtcctttttg acctgacgag taatgataag
    13561 ccgtggatag tgctcattgg tgattttgat aaaaggataa gacttgtcat ccttgagcat
    13621 gatattgtac ttgggcttat tttccttgat caggttgatt tccagcagaa gcgcctcaat
    13681 attagactcc gtaacaataa attcaaaatc cacaatttca gacaccaagg cctctgtttt
    13741 ggtatcatga cttccacgga aataagacct cacgcgatta cgcagatttt tagcctttcc
    13801 tacatagata atggtgccgt ttttatcctt gtaaatgtag caaccagggc tggtcggcaa
    13861 gagctctagt tttggtttaa tcaagttgtt catagttcca ttatagcaaa aaagtaggga
    13921 aagatagtac cctactcatt agtctcatat atttttcgga ggtttgcaac atcctcttcc
    13981 tggataccat aaaaggaacc tgctggttgc atgacagact tctcatctgt atggtccaag
    14041 ccaatcgcat gacctaactc atgttctgcc gtatggacaa ggcgttcata ggaatagcca
    14101 tagtatggat tggacaaata ataatgattc aaccgcaccg ttacggacaa gaattgccct
    14161 gttaagagat tagtttgact ttccgcctct cctgccacag gagtgcctcc gtcgttcatc
    14221 tccgtagccg taatatccgc cttactagac tcagtcacga gttcaaagtt aaaagcacca
    14281 gtttgattcc agttctggat tgcttctaaa taagcctctt gaaagcgtga atccatctgc
    14341 ggatccaggt aaatacgagc agaggcctgt ggccaccttc cttcagaatg ctggtgacta
    14401 tctgtctggc ttaacttagg cagttgccct gttttctccc attggtcaat actttgttga
    14461 ccaattttta ctgaccgttc tgcttgcttt agcgctcctt gaaaatcccc gttcagatac
    14521 cagagaagtc cgaaagcaag cacacataag agcacaacta tccaaaccag acgccaaaac
    14581 aaacgccaca caaaagaaaa gaaagcccct atcaaacgaa aaagccagcg catgtctctc
    14641 cacctttcta gcaaataaaa attattttac taaaagaagc taaaagaaat ctaaatactg
    14701 actttttcat cttaacgtcc tactattttt ttgagtaact ggatagcttt gtattttaaa
    14761 ggagatggat ggtaacggaa agtacctgct ttgcgtacaa tatagccatt aaaattctgt
    14821 ttaaaacgca aaacaccatc acttccatca aaaatccctt gaatgcctag gaagttgtat
    14881 ttaggtattc cacgttttat gctttccaac ataacatatt tttgaagcag tgcaggggca
    14941 tagaacttat taaactcagt gtaggaacca ctaaagagat aagtcgtttc ctgaggcata
    15001 taaacaaata aactcccagc taaaacaata tcttcttctc catatttttc aatcaagtct
    15061 cgcgcttctg cttttcgaac ttcaaacgtt tcaaattgac tagaatattc tctcagttga
    15121 ttttgttttt tctcagaatg aggattttta ctcaaatcaa gtcgcaactt gtccaagttt
    15181 tcttctagtt tattttgttc accttgcaat ttgctcatat agtccgaaaa atttaagctt
    15241 gctatgagaa actccgcttg ttctccaaaa gtatcataaa aatgctcata atattctaaa
    15301 cttttatcac tatattctct acgttcagag gtttcttttg ttatattctt aaaaatcgat
    15361 agttcttcac gttttaactt tttcaatcga atgccaaagg tttcagcctt tttcaccaag
    15421 ggtttaccct ttttgctaaa acttttaagc aaactctttt cagttaattc agttaaatct
    15481 ttatagtata accaatctgg ttctccacct gggtaacctg ttgttaagcc atcaaattga
    15541 taacctaaat cagtcaaacc ttgaataata ctttttttct cagcatctat tggattacct
    15601 tggctatcaa aagtttgata agtttcataa ggttttacaa gcaactctaa tacaccattt
    15661 tgcttggcat attcttttaa ctctgcataa aaaactggaa gagcatcttg ttgggtataa
    15721 atcggccccg aattgagttc catatgcaga ccacccagca tgggcaagct ataaaccaga
    15781 gctgcaactt gaatttctcc ttcttgtttc aaagcaagat aaacaattcg agcccctctt
    15841 ttttctagca aatcccccat ctggacagat tgcataaagg aacgagaaga aacctgatca
    15901 gaataagtct gaaactcttc tttcgtgagt gttgttagtg ccatatactt actttctatg
    15961 tttttttctt aatgttttac ggaaatcaag agcaagtctt aacagaggat agagaggatg
    16021 agtgggcatt gtaaattcac ccaagtattc ttcaatcgtt ggattaaatt tttccttaaa
    16081 atgataaagt ccaccattga gagagttttc aacaccacct aaattttgcc agaccatacc
    16141 tcgctcaaag gcatagcgag ccgtttcata ccatgttaaa attggtgcat tgtaacgttt
    16201 aaaatcatca tccataccag catatatatt gacagaggta gtaccaaatt ccaaactcaa
    16261 agtagccgct aaaggaactc tcgcttgacc tacatctata tattcctgca agaaggtcaa
    16321 ttcctctaac aaacgttctt tttccttctt ctgcgcttct acttttgaag ttcgagtcga
    16381 ctcagtaaag gtctcttcca aggctctatt tttcgctaac tgttcttcta attcttgcga
    16441 acgtttagaa acatccaagg tggccaaggt gatataggcc ttgtccttaa aattatctaa
    16501 caatttttta taataggctt cattcctcaa atgaatctct tttcgcttct cagttttttt
    16561 catcaactcc gaaaatgaat ctaatagttc cagtccacca tattgaatct caagcccttt
    16621 gtttcgtgct gttcgaatag cctgttttgt tgacttggaa agtttatctt cttcaaaatt
    16681 ttccttgtat attttcgcct gaatacgagg ttgaatggtg tctcccattt cctccgtttt
    16741 tcctgaccac cttactccca tttgttgcaa actatcaata atagccagat tttcaggaaa
    16801 ttctgtcttt tcctgattga ttaaactttg agataggcaa atacttgggt caaaagtcac
    16861 aaaaaccgct ctcttactgc gagcatagga cttaatagac tgaatggcaa aattcaagag
    16921 ttctttatcc ccataatcca atataggtcc tcttgggatg taaaacattt tatagcctag
    16981 cggaagagtt ctaatcaaaa tactagctgt cgccagtaat ttttcttccc tgtaaacacc
    17041 aaacttctca tgttgccaat tagacttaac ttcctcccaa gcactacttt gtaatacatt
    17101 ggctaattca tgttctttga caaactgatc atattctaat gtgggaatgc caatttgata
    17161 acggtacatt tcctactctc tttcctccag tattttatta ctattctact actttcgttt
    17221 gaaaagtcta gtgaaaacat attttatttt agttctactc cccctatgct gaagttcaaa
    17281 ctaagtcagt ctctcttcta atttgaaatc aattggtagg gttgttaaaa aaacttccaa
    17341 ttgtttttcc cagtagtacc actcgtgagt tccagcacta tggctatagg tcacatcaaa
    17401 acctagtttt ttgagatttt tcactgcgag attattggct tcgtacaaga aatcctgttc
    17461 gccacaccac gcccaaagtt tggtcttttt atccgatttt ttagccagac tttcaagaga
    17521 atagggacta gttgtccagt ctctaatctc tccaaaaaca cctctccagt aggctggact
    17581 tcccagattt tgactttcag gagaaaagtt ttgaaagctg agggcacctg aaaaactagc
    17641 tgcatgagaa aaacgatttg tcgtaagagc cagtttgaag cagccgtagc ctcccataga
    17701 aagaccagcg ataaaggtct tttcacgctt gctagtcata ttagggaaga agcgtttcag
    17761 aacctgtggc aattcctctg ctagagccgt gtagtagtca aaaccatact gggtatcggt
    17821 gtaccaacca ttgctggtat tgggcataac aacgatgaga ttagttcctc gaagcaagcg
    17881 ttctacattg gtccgcttaa gccaactatt atgatttcca gacatcccgt gcaaaaggta
    17941 caagacggga atatcttcac actctggttc ttccactcga ttggcatcag ggtagaggac
    18001 attcaccccc cactccatat ccaatacttg tgagtaatac tcgattttca ttactgccat
    18061 gattttctcc ttctattttt ctataagaaa aagccgaaac tcgactttct ctctgtttat
    18121 ttcaacgatt attttgcttc catgactact ggtaaaatag ctggacgacg cttggtttgg
    18181 tcaaagagat acttggtcaa attatctcga accttccctt taagatctgc ccagtcaaag
    18241 tcatctcctt gaagataatc ttctaccgtt tggttaatca attctgaact ttcacggaga
    18301 atatcgcgac tcttcttgag ataaacaaat ccacgcgtgt gaacacgagc cctagccaca
    18361 attttcttct cacgacggtt gactgtaata gccacgatga aaattccatc ctctgacaag
    18421 accttacggt cacgaagaac aacatttcca acatcaccaa tggcattccc atcaatcaag
    18481 atatctcctg ctgaaaccga tccagctgga acaaagtctc cattctcgta agccatggtc
    18541 gtcccctttt taggaatgaa aatgcgttct ggcaacatcc caactgccat ggcagcctta
    18601 gcgtgagcat ccaactcacg atactcccct tggacaggga agaggtactt aggttgcaaa
    18661 agattgatca tcagctgcaa atcacgcaca tttccgtgcc ctgatacatg taaactttgg
    18721 gtaatcaatt tgacaacccc acctgcctga taaatcatat tttccacacg cgcaacaaag
    18781 gcttctttag caatagacgg agccgtagca atatagacca ggtccccatc cttgatttct
    18841 acataacgat ggcgaccaat cgacatctta cgaagtccat tgataggttc acccatacga
    18901 cctgtctcaa gaataatcaa ctcatggtct tcaaagcgag acatatcttt aggcttaatc
    18961 aagagaattt cgttggctaa agacaacttc ttaagacgaa tcgctgtgcg gacgatattt
    19021 tcaatatcaa atcctgtcaa gacgatacgt cgacctgttt tatccgcagc gtcaaaaatc
    19081 tgctgaatac gagaaagatt actggaaaca gctgcaacga tgatacgacc ttcccagtca
    19141 gcaatagttt gggtaatttc atccctaact tcactttcac tagccacctg aatattgctg
    19201 tctgcattgg ccgaatcact gaggagagcc aggacgccgt cacgaccaat ctctgccaaa
    19261 cgagcaaaat cagttgcata agattcacta gccgtttggt caaatttgaa gtcacctgta
    19321 taaacgatgc ttccttccga tgtcttcaag acaattccca gactctctgg aacggagtaa
    19381 gtcgtaggga agaaggaaac cactgtccca ccaaaatcaa tctccgtatt ctcatcaatg
    19441 acatggaaat cattaaattt cttaacggca tcatttcctt tgacaaagag ctttgccaac
    19501 tcaatggtca actcagaccc aaatacagga actttagcct ctgccaagag ataaggtaga
    19561 gcaccaatgg catccgcatg cccgtgggtc aagaaaaccc cagcaatacg gtcgctattt
    19621 tcaaaaaggt aatccatgtt tggaatcacc acatcgaccc ctaattgttc attttcagga
    19681 tattttaacc ctacattcaa aacaaaaatg gactctccaa tttcagcaat gtacatattt
    19741 tttccattct cacgcacacc accaagtgtt gttaaactga tattactcat ttttcctcca
    19801 aaatcttagt ttatcttgat tatagggcaa ttctaccctc ttattctaaa agttctgata
    19861 ctttcagccg aatcttttcc taccattata ccattttttt gatgattttc aaaatgaagg
    19921 tctgttttca aaaaagagtt gatttcccaa ctctttccta acttctactc tttttccatc
    19981 aaaaaatcat aaatttcttg caccgtaccc agcgccatca tttcttggtc tttaacggtt
    20041 tgtttgagat tttggtaaat ttgactttct cctatctccc gctttggcgc ctctttattg
    20101 actgtcatca caccatcttt tatcgtcaca aagcctagtt cttcaaatac ttgaatcatc
    20161 ttgaccagca agatttgttg aatattaaga tatgcagcca aatctttcag cttgtagcga
    20221 atatcaaact ctgggaactg gtaaatagtc ttgtacaatt tagcaaactg atctctagtc
    20281 ccataacctg tcagataata ggtcttgtca atatcatttt tgaaatagac agcagagaaa
    20341 tgctgttcct gaaaaatggt cttcagctga gtaatatcct ctggaatgtt ttttacgaca
    20401 acagcttcac tagccgcaag atttggcagt tctccaggaa aatccaagac tggaacacct
    20461 tctggcaaga ctgcattttt tccacgaatg ttaaaaagtt gaacaccttc cactcgcgca
    20521 tccaccatca tcaactggag ggcagtttgg ccattccatt ggttgacaga caatttaacc
    20581 gctaactcta gattcttggt ttgagaaaac tctgtcgccc atctgccttg accaaaggct
    20641 accacttcaa aactcgcctc acccttggaa attttcagct ttagatgggc attacctgcc
    20701 cccatagtac gagcactttc gacctgaaaa ttcttgatat aaaaaatagg tttctgatta
    20761 tccattccaa aaggagctaa acgttcaaaa cttttgaccg tttccaagct aagtgcctcc
    20821 aaatccaact cttcatctag gtttaactta ttcttgccac cagcatctgc acctttttca
    20881 cgaacataat cttccaaaac ctgagataaa tctgagagtt gctcaacttc cagcgtcata
    20941 cccgctgcac ctgcatgacc tccaaaggcg atgaagaggt ctcgatgggg atccagagct
    21001 tcaaaaatat cgaccgcttc cacactacga gcactgccct tggcacgacc gtcttctata
    21061 ttaagaacaa tgactgtctg tcccaattct tccaataaac gaccagccac gattcctaga
    21121 accccaggat tccagccttc cttggccaag acctgaacct tcttctcagg atccaccatg
    21181 gtcttggctt cttcatagat agactgaacg atttccttgc gctcttcgtt tttctggtga
    21241 atcataaggg caatctcatg cgcttcctca tcatcaaatc cagtcaacaa atcaatggca
    21301 ggattgggat catccaagcg acccaaggca ttcaaacgag gagcaatctg gaaaccaacc
    21361 gtttcttctg ttacttcgtt ggcagcaatc ccagccatgt ccagcatttc ttgcagacca
    21421 atgcgctggg tatgacccaa catttccaga ccatattgaa ctaagatacg attttcatcc
    21481 gtcagactca ccatatctgc aatagttcca atagcgacca aatcaagcaa ttccacttgc
    21541 acttcttcta acagggcaca agccaacttg aaagcaactc cacaaccagc caaatattta
    21601 aaaggataat ccgcatctgg atgttcagga tggacaatag cataagcatc tggcagggtt
    21661 tcaggcatgg aatgatggtc tgtcacaatg acatctactc ccatagactg agccaatgca
    21721 atagcctcat gaccagcaac cccattgtcc accgtcacaa tcaaggaaat tccttcttgc
    21781 tcgataaagt atttataaac actagcatta gggccatagc catcggtaaa acgatttggc
    21841 aggtaaactc ggcactcagc accaagttgt tccaaacttt ccttcacaat agaagccgaa
    21901 gtcatgccat ccgcatcata gtctccataa acgagaatat tttccccttc ttcaatagcc
    21961 tgacgaatcc gctccactgc cttgtccata tcatggagca gataagcatc atgtaagtcc
    22021 tccaaggaag gttctaaaaa cttcttcaga ctttcttggt cctgaatccc tctctcaaac
    22081 aataaccgag ccacctcagg acccagtcca gccttcttgg ctatctttgt aaaatccgca
    22141 tcttctacct gcagggcaaa ctgccattca taagtaggtg ttatcaaaaa gacatccact
    22201 ctttctaaga attctattgc ttcattataa catgatttag acgttttctc tatccagatt
    22261 gcttttttat aacattttat agtatattga aactagaata gtacacctct acttctaaaa
    22321 tattgttaga aatcgatttg actgtcccga tcgatttttc ctgttcttat ttcactatag
    22381 tgaatttttt cagatatgat ttgacaagaa cattctttta ttgcagaatc gtgttataaa
    22441 atctaacata aaggagttct ctcatggttt tagtagaatt taaaaacgtc gaaaaatatt
    22501 acggagacta ccacgcactc cgcaacatca atctccgttt tgaaaaagga caagttgttg
    22561 tcctgcttgg accttctggc tctgggaagt ccactcttat ccgtacgatc aatggtttag
    22621 aggctgttga caaaggaagt ctcctagtca atgggcacca agttgctggt gccagccaga
    22681 aagatttggt acctcttcgc aaggaagtcg gcatggtttt tcaacatttt aacctttatc
    22741 cacacaaaac agtgttagaa aacgtgacac ttgcgcccat taaagttcta ggaattgata
    22801 aaaaagaagc tgaaaaaacc gccaaaaaat atctggaatt tgtaaatatg tgggacaaga
    22861 aagattccta tcccgccatg ctatctggtg gacaaaaaca gcggatcgcc atcgctcgtg
    22921 gtcttgctat gcatccggaa ctcctcctct ttgatgaacc aacatctgct cttgatcctg
    22981 agactatcgg agatgttcta gcagttatgc agaaactggc gcgtgatagg atgaacatga
    23041 tcatcgttac ccacgaaatg ggctttgctc gagaggttgc ggaccgcatt atctttatgg
    23101 ccgacggaga agttttagta gatacgacag atgtcgataa cttttttgac aatccaagcg
    23161 aacctcgtgc ccaacaattc ctcagcaaaa ttatcaacca cgaaagtgac aaagtcaaat
    23221 aaggaggcgc ctatgaaaaa aaattctttt tatcagcatt attgattagc cttttcggcc
    23281 ttgctgctgc caaaccagtc caggctgata caagtatcgc agacattcaa aaaagaggcg
    23341 aactggttgt cggtgtcaaa caagacgttc ccaattttgg ttacaaagat cccaagaccg
    23401 gtacttattc tggtatcgaa accgacttgg ccaagatggt agctgatgaa ctcaaggtca
    23461 agattcgcta tgtgccggtt acagcacaaa cccgcggccc ccttctagac aatgaacagg
    23521 tcgatatgga tatcgcgacc tttaccatca cggacgaacg caaaaaactc tacaacttta
    23581 ccagtcccta ctacacagac gcttctggat ttttggtcaa taaatctgcc aaaatcaaaa
    23641 agattgagga cctaaacggc aaaaccatcg gagtcgccca aggttctatc acccaacgcc
    23701 taattactga actgggtaaa aagaaaggtc tgaagtttaa attcgtcgaa cttggttcct
    23761 acccagaatt gattacttcc ctgcacgctc atcgtatcga tgccttttcc gttgaccgct
    23821 ctattctatc tggctacact aataaacgga cagcactact agatgatagt ttcaagccat
    23881 ctgactacgg tattgttacc aagaaatcaa atacagagct caacgactat cttgataact
    23941 tggttactaa atggagcaag gatggtagtt tgcagaaact ttatgaccgt tacaagctca
    24001 aaccatctag tcataccgca gattaaggag gataccctat gacagattta tcatcttgga
    24061 cagcctattt tcaggatttt ggacaatttt tcaatggttt cctctttact cttgccctag
    24121 cgattggatc ctttatcctc gccatggtct taggaatctt ctttggtgcc atgtcaacca
    24181 gtaaacgtcc aattttacgc attttagctc gcatctttgt ggaattttac caaaatactc
    24241 ctctcttggt gcagtttgtt attgtttttt atggcctacc tcttatcagt gaccatatca
    24301 tcatgattcc aatttattgg acagccgttc tctgcgtggg actctatcac ggcgcttata
    24361 tcgctgaggt tattcgttca gggattcagt ctattcctag tggtcagatg gaggccgcct
    24421 tgtcgcaagg ttttacctat atcagtgcca tgcgcttgat taccttgcct caggccttcc
    24481 gcatcattct ccctccattg accaaccaaa ttgttaacct catcaagaac acctctactg
    24541 tagctatcat ctctggagta gacttgatgt ttgtgactaa gtcttggtcg gctctcaacg
    24601 gaaactatat cccagccttt ttaggtgcta ctcttctcta ctttgcccta tgcttccctg
    24661 ttgcccagtt tggtcgcaag atggagcaag ccaacaaaaa agcctattca ctttaggagg
    24721 ttactatgga atctatttta gaagttttaa ccccagataa cctagtcttt atctttaaag
    24781 gatttggctt gaccctctat atttctctga ttgccatcat cctctctact atcatcggta
    24841 cggtgctagc tgtcatgaga aatggcaaaa atcctgtctt gcgaatcatc tccagcattt
    24901 atatcgaatt tgtgcgcaac gttcccaacc ttctctggat ttttactatc tttttggtgt
    24961 tcaaaatgaa atccacacca gcaggtatta cagcctttac tctctttaca tcagcagcct
    25021 tggctgagat tattcgaggc ggtctcaatg ccgtagacaa gggacaatac gaagcaggaa
    25081 tgtcacaagg cttcacctca gcccaaatcc tctactacat cattctccca caagccatcc
    25141 gcaaaatgct accagccatc atttctcagt ttgttaccgt gattaaggat accagcctcc
    25201 tctactctgt tatcgcccta caagaactct ttggagccag ccaaattctc atgggccgtt
    25261 atttcgaacc agagcaggtc ttcagtcttt gcatcctgat tgccctcatc tacttcagct
    25321 ttaacctagc aatttctagc ctgtctcata tgctagccaa acgttggcaa caagctgcag
    25381 aataatactc ttcgaaaatc tcttcaaacc acgttagctc tatctgcaac ctcaaaacag
    25441 tgttttgagc aacttgcggc tagcttccta gtttgctctt tgattttcat tgagtataaa
    25501 cagccactct ccagttcaat tggagagttt tttgatgaga gtagatattt atagacctca
    25561 atttgacacc atacattttc tatgataaaa tgtaacaaat ttatttacaa caaatcgaaa
    25621 tctaaatgaa atggaatttt ctatgaaatc agtcaaagga ctactcttta tcatagctag
    25681 ttttatcttg actcttttga cttggatgaa cacttctccc caattcatga ttccaggact
    25741 agctttaaca agcctatctc tgacttttat cctagccact cgtctcccac tactagaaag
    25801 ctggtttcac agtttggaga aggtctacac cgtccacaaa ttcacagcct ttctctcaat
    25861 catcctacta atctttcata actttagtat gggcggtttg tggggctctc gcttagctgc
    25921 tcaatttggc aatcttgcca tctatatctt tgccagcatc atccttgtcg cctatttagg
    25981 caaatacatc caatacgaag cttggcgatg gattcaccgc ctggtttacc tagcctatat
    26041 tttaggactc tttcacatct acatgataat gggcaatcgt ctccttacat ttaatcttct
    26101 aagttttctt gttggtagct atgccctttt aggcttacta gctggttttt atatcatttt
    26161 tctatatcaa aagatttcct tcccctatct agggaaaatt acccatctca aacgcttaaa
    26221 tcacgatact agagaaattc aaatccatct tagcagacct ttcaactatc aatcaggaca
    26281 atttgccttt ctaaagattt tccaagaagg ctttgaaagt gctccgcatc ccttttctat
    26341 ctcaggaggt catggtcaaa ctctttactt tactgttaaa aattcaggcg accataccaa
    26401 gaatatctat gataatcttc aagccggcag caaagtaacc ctagacagag cttacggaca
    26461 catgatcata gaagaaggac gagaaaatca ggtttggatt gctggaggta ttgggatcac
    26521 ccccttcatc tcttacatcc gtgaacatcc tattttagat aaacaggttc acttctacta
    26581 tagcttccgt ggagatgaaa atgcagtcta cctagattta ctccgtaact atgctcagaa
    26641 aaatcctaat tttgaactcc atctaatcga cagtacaaaa gacggctatc ttaattttga
    26701 acaaaaagaa gtgcccgaac atgcaaccgt ctatatgtgt ggtcctattt ctatgatgaa
    26761 ggcacttgcc aaacagatta agaaacaaaa tccaaaaaca gagcttattt acgaaggatt
    26821 caagttcaaa taagtaatca tactctcctg ggatttccca ggagagtttt ttatagccaa
    26881 atgaaataag acaggaacga tggaattttg gcattcaaat caattgataa gaatgtttta
    26941 tagtggagtg aaataggata cgaacaaatt gattaggaaa atcaaatgaa tttatagaaa
    27001 tcttttagca gttatgttgt cctattctag tttcaaaacg ctatagaagc agcattgtgc
    27061 tagtctagat tcagtttact atactaaaac gagtagcttg aaatcaaaaa acccaccctc
    27121 acaggcaggt tttatctgta ttattcagct agattatgct ttaccttctg aaccgaatac
    27181 gtcgatacgt tcttcaaccg atgcttggat agcttttaca ccgtcagcca agaatttacg
    27241 tgggtcgaag agttttttct tgtcgtattc tgcttcgttt gcttcgtagt cacgagcaaa
    27301 tttacgagtt gcgttagcga atgcgatttg gcattctgtg ttaacgttaa ctttggcaac
    27361 accaagtttg atagctgctt ggatttgctc atcaggaata cctgatccac cgtgcaatac
    27421 gattgggaat cctggaagag cttctgtcaa tttttgcaag tggtcaaggt ctagaccttc
    27481 ccagtttact gggtaagggc cgtggatgtt accgatacca gctgccaaga agtcgatacc
    27541 agtttcaacc attgctttag cgtcttcgat tggagccaat tcacctttac cgatgattcc
    27601 gtcttcttca ccaccgatag taccaacttc agcttctact gagatacctt tagcgtgtgc
    27661 tttttcaaca acttctttag ccaatttaag gttttcttca actggaaggt gtgaaccgtc
    27721 aaacatgatt gaagtataac caacttcgat acactcaagt gcatcttcgt agtgaccgtg
    27781 gtcaaggtgg atagctactg gtacagtgat acccattgat tcaacaaggt tagcgatcaa
    27841 gttgcgagca actttgtaac cacccatgta tttagcagca cccattgaag tttggatcaa
    27901 aactggagct tttttagctt ctgctgcgcg caagatagct tgagtccact caaggttgtt
    27961 tgtgttaaat ccaccaactg cataaccgtt gtcacgggct gcttggacaa atttttctgc
    28021 tgaaacgatt gccattttat caggcctcct gtatattttt atgggtcatc ccatttacat
    28081 tgttcatttt atcacttttt gccaaaaaaa tctagttttt cccgcagttt cgattgattt
    28141 tcttctaact ccatctatgt aaaccctttc tccctagtct tggacgactt ttggaaaatc
    28201 tataaagaag gttaaacgat tctcctccat ctcgaaacga taagctaatt tttcatgttc
    28261 taatagactc ttaaccacaa agagccccat accagacccc ttgaccttgc gactagcatt
    28321 gtcagaaaaa gactgggcta gtttttcttg ttcctctgag ctacagctat tttcgataaa
    28381 aagttctcct tctctttctc caattcgaac taagccacct ggaacagagt gcttaatggc
    28441 attgctgatg agattagaaa gaatcaactt cataactgat gggtttagat aagcctgctg
    28501 atgggtcaaa ctattgtcta tctggagctc tctttccttt gctagcaagg cataatcttt
    28561 gaccagattt tgcgtcatct ggaggaggtc aattgtttcc ctatcatctc gcaattcctg
    28621 cacagaagag agggaaagta tctgcagaac atggtgattg agttcatcca caatccccaa
    28681 ggcaactccc agatactggt ctctatcctt ataacgaccg atattctctc tcatattttc
    28741 gattaggatt ttcaaactag ccagcggtgt tttcaattca tgagaagctc ctcgtaggaa
    28801 ttcgaccttc atcttctcca gctggagaat ggcttcattc ttttcatgca agtccgcaat
    28861 aacagtcaag agatgctggt agaggctatt gatttgttcc ttgagattac ctatctcatc
    28921 cttagaatcc acgcgcaatc gcacttggga atccaggtcc atcatccgac gggtcacccg
    28981 cttgatttcc aaaatcggtg caacaatagt ccgagcgtag atgtaggcca ccaagaggga
    29041 aatcagaaag gaggccagca aggtataggg aagaaactgg agactgattt gctccgcttc
    29101 cttttgtaaa tccatggaag ctagaaactg gagaatcata gtaccaccgt cttgcgtttt
    29161 cacctcgcgc tcctcaataa agagagaggt tgtctggcgg tctgtgtcca gaggaagact
    29221 gtccttgact tctaacttgt cctcggtcat ctcacctttg acggtcccct tgatatcact
    29281 agtctgggaa tacaagtcta acacttgctc gatactctgc ctatctttcc cttctaggga
    29341 ctgggcaatg gctgttgcct tttgaccaat ggtttcctga cgatgactca gataagtcga
    29401 aggaaaaaga aaataaatag ctaaatgaag gcagataacc agaacactaa atatcgagaa
    29461 ggtatagata aatatctttg caaataaacc tgttcgtttc attttcgctc caatttataa
    29521 ccaacattgc gcacagtgag gatacaatcc aagtctagct ttttccgcaa ttccttgata
    29581 taaacatcaa taacacggtc aaagggaacc tcatctgtcg ctttccagac ggcatcgata
    29641 atctgagatc gagtcaaggc ccggccttca tttttcacta gatagtccag aatttccaac
    29701 tctttggcat tgataggcac ttcttgacct gcgaggcttg cactgtagct ttcaaagtcc
    29761 accttggtat ccttgtaaga aaagattcgt cctgtatcgt agtagcgctt gaaaatcgcg
    29821 tccaccctca cttttaaaag ggagagggag aaaggttttt ccagatagcc atctgccaaa
    29881 gaggcaaagg cactcatctt gtattcctca tcttgaaaag ctgtcaacat caagacagga
    29941 acctgactgg ttttacgaat ctcagctagg acttctaagc cgttgagctt gggcatctgg
    30001 atatccagta aaaccagggc cacctcatag ctagaaaatt gctccagagc ttcctgaccg
    30061 tccgctgcct caatagtttc atagccacaa tccgtcaaat aatcactgac cccctcacgg
    30121 atcatctctt catcttctac aattaaaatt ttcatacttt aactgctctc tattttttat
    30181 ttttcttaga ataaatacct accctatttt ctattatagt ctcttgctgg ccttttgtct
    30241 gcaagcaact gaccactaga taaaacgttg tgaaattcct ttctcataaa ttccataact
    30301 ttagtatatt atatttaagc actaaagtac aaagaaagca actgaaagca atgattttca
    30361 ccactgcttt cggatttatt ttgaattgtt aaatagccat tcctatccac tattcttgaa
    30421 tagaaacaca agatgcaatc tttattctag actcattttt tcaaatttat tcaccatcca
    30481 gcaagagctc ttttggttgt tttctaagga gattgcttga agcaagcgcc ataacgagaa
    30541 ccactagaac caaggcaagg acaaaaatga tgataaagtc tgatgtctga atggaaatgt
    30601 ctaggctcga caaggtcttg ctaaagccat ctacttctgc accaccacca aggttagagg
    30661 cttgagccgc cttactagcc tgtttggcaa cacctgaagt cacattggca aggacagtgt
    30721 ttccaattgc acgggcagtg taattagcta ggaagtaagc agaaactaga gcagggatag
    30781 caatcaagat agattcggtg atgaattgac ccaagatact tgcctgcttg aggccgatag
    30841 agaggagaat tcccacttcc ttgcgacggg cgttgatcca aaggctgagc aagagggcaa
    30901 ggaggagaac tgagaagctc aagctacccc agaagaggag gttggccatc ttgtacatac
    30961 cagagataga ttgctcaaga gctgggtagt tagaggagct cttgacgagt gtgtagctct
    31021 tccagttgat accactgatg ccattcaact ctttcataac atcatccaag ttcttgtctg
    31081 ctgttacaaa gaaggttgcg tccccataaa tggctgtgtc ttctgtgtat ccataaagtt
    31141 ttgcagcagt gtgaatgtct gtaatagctg tgttttcgta aagttcttgt gagtaggtta
    31201 ctgctgactt attatgacca tcaaagagtc ccttgattgt cacttcaact gtttccttgg
    31261 ctcctttttc attatctgca tcgtagatat tagagtccag tttaaccttg tcccctactt
    31321 tccagccgtg tttggctgcc aagtccttgt gcaagaggat tttatccttg tcgtcgttgg
    31381 ttaagtgctc tccttcgact agtttataag aaccagagac aaacttgtct tctttagagg
    31441 agtcattgac acctgtaatc atcaagctac ttccaaaacg cttggcacga tcagcagtga
    31501 gattcttctt ggtttctggc gtttcaatca ggtcatatcc agtcaaatct ccgatagcgt
    31561 tgatacgttt gacataagac tcaatggcct tgttttcggt gatttttttg atgtcttcac
    31621 ccttgatatt cccagcacca cgaggcgttc cttggttgac gcgacgattg atttgcatgg
    31681 agaagctatt ggtgatattt ttaaaggtct cctgagaagc cttggcagta gctcccttga
    31741 ttgacaagcc gaccaaactc aagctcgcca tgaggagaat aatcaggaag atgacaatcg
    31801 atttgaaaaa cttccttgta acataggcaa atgcgttgtg taacatagat tccctttcta
    31861 gattttgttt taatcattct attaaaataa gctcaaatta tttactagta ttgcgcgttt
    31921 cagtcagttt cttatccttt aattcaagtg taatatctga cgcttgtgcc acttctttac
    31981 tgtgagttac gacaatcaca catttacctg ttttctgggc aagtgatttg agtagttcga
    32041 caatatctcc agcagtttta ggatccagat ttcctgttgg ctcatcagct agaataactg
    32101 gagcttctga gaccaaactg cgagcaatgg caacacgttg ctgttgacca cctgataact
    32161 ggagaacatt ccgcttgatc tggctttcat ccaaaccaag ctcaagaagt gtattcttgc
    32221 ttgccttttt gttgaccaat cggatatttt ccagcggaga aagataatct atcaagttat
    32281 aattttgaaa gaccagggaa atatggtgca tgcgatggta agaatagccc ttcttacgaa
    32341 tatcctctcc ttgaaaaagg atagaacctt caacaggact atctagacca gcaagtaggg
    32401 acaagagtgt ggattttcct gctcctgact ccccaataat actgtaaaat tttccgggtt
    32461 caaaattata attgatctga tataggactg cttcagcagt attcttataa cggtaggtaa
    32521 catcttgtaa ttgtaataaa gtcatgattt ctccttctta actaatagat gataaaattt
    32581 ctttcggtga ttttctaaat aagaatagga aacaaagggc tacagataag caactaagca
    32641 gaactagaaa aacataggat tctgcaaaag ataagatgct agttgataaa ctgcttgctt
    32701 tggctagtgt atcttgtaag cttgcctgat ctccacttgc tagtagagtt tggagtaggt
    32761 aagttgtgat tgcgtttcct gcaacaaatg ctggaagcaa agctccaaga gataccaaaa
    32821 ctacctctaa acagaattgt aggaagatcg agctcttgcc ttttccaagt gcaagtaaaa
    32881 tccccacttc atagacccgt tctctcaacc agagagacaa aaccagaatt aaggctccag
    32941 ctcctgctat caacatccca taaaggaaga tggtcaggaa ggtttggaaa gttgcaactg
    33001 agtctttgat ttgttcaaaa gccttgtttt ccttttcgac ttggtagcct tgattttcca
    33061 aggccaagtt ttctacctgc ttcatgagtc cgtccatttc cttaggattt tctacataga
    33121 agcgtgctgc actgacttga gcttcactat tgcccaaaag ggtttggcta ctttcatagt
    33181 ctgtaaagac ttgattttca ctgaagtcag aagacaagcc tgtgaatttc tcttgttttt
    33241 taccagaaaa gatgccgata atctcaaact ctactgtttg tccttttcca gattcagact
    33301 gaccagcatc caagccaatc ttgtcatgaa gcgaaagacc gttcttctta gccaattctt
    33361 cgtggataag gattttcttg gaatcccctt tttgaaggtg tcgcccttct tttagattga
    33421 aagccgaact ggtaaaggtt acatccttgg atgaatcctc aagagccgtt aagctaacca
    33481 agttattgtc tgcagctgat aaatcatcac gctccacgct ctgctcgcca gtcactgctt
    33541 ccttgtcttt tagttttgcg accgtctcaa gttcaggaga gacattttcc agccccttaa
    33601 tcttgcttac agatgctagg tctgacaact tgaatgtctg accattctct atcttcttaa
    33661 tagaaaaaga tgtattgagt gatttataaa gattgctttc tactgttttg ttggacttca
    33721 tcagagtcaa acaggctgaa attccggcca ataagaccaa taaaatcaga aataaaataa
    33781 aacttctcag tcgctttctg ctgacataag cccaagatct ttggattgga ttcatttgtc
    33841 acctccatat ttgtaagact attataaaac ccaaatatga aatgtttatg aaatacgaaa
    33901 aaaaaatatc gagtagggga taatctctag cccctctcac accacc
//
LOCUS       DAVKEV010000024        33844 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVKEV010000024 DAVKEV010000000
VERSION     DAVKEV010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33844
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.024"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(59..295)
                     /locus_tag="VWZ68_001183"
     CDS             complement(59..295)
                     /locus_tag="VWZ68_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9372210.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(308..781)
                     /locus_tag="VWZ68_001184"
     CDS             complement(308..781)
                     /locus_tag="VWZ68_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372211.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(799..984)
                     /gene="briC"
                     /locus_tag="VWZ68_001185"
     CDS             complement(799..984)
                     /gene="briC"
                     /locus_tag="VWZ68_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEU9372212.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(1143..1910)
                     /locus_tag="VWZ68_001186"
     CDS             complement(1143..1910)
                     /locus_tag="VWZ68_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEU9372213.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKHAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(1907..2773)
                     /locus_tag="VWZ68_001187"
     CDS             complement(1907..2773)
                     /locus_tag="VWZ68_001187"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEU9372214.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(2810..4177)
                     /gene="accC"
                     /locus_tag="VWZ68_001188"
     CDS             complement(2810..4177)
                     /gene="accC"
                     /locus_tag="VWZ68_001188"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEU9372215.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(4189..4611)
                     /gene="fabZ"
                     /locus_tag="VWZ68_001189"
     CDS             complement(4189..4611)
                     /gene="fabZ"
                     /locus_tag="VWZ68_001189"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEU9372216.1"
                     /translation="MIDIQEIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(4608..5093)
                     /locus_tag="VWZ68_001190"
     CDS             complement(4608..5093)
                     /locus_tag="VWZ68_001190"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEU9372217.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(5096..6331)
                     /gene="fabF"
                     /locus_tag="VWZ68_001191"
     CDS             complement(5096..6331)
                     /gene="fabF"
                     /locus_tag="VWZ68_001191"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEU9372218.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(6353..7084)
                     /gene="fabG"
                     /locus_tag="VWZ68_001192"
     CDS             complement(6353..7084)
                     /gene="fabG"
                     /locus_tag="VWZ68_001192"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEU9372219.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(7118..8038)
                     /gene="fabD"
                     /locus_tag="VWZ68_001193"
     CDS             complement(7118..8038)
                     /gene="fabD"
                     /locus_tag="VWZ68_001193"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEU9372220.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(8031..9005)
                     /gene="fabK"
                     /locus_tag="VWZ68_001194"
     CDS             complement(8031..9005)
                     /gene="fabK"
                     /locus_tag="VWZ68_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEU9372221.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(9124..9348)
                     /locus_tag="VWZ68_001195"
     CDS             complement(9124..9348)
                     /locus_tag="VWZ68_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU9372222.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(9408..10382)
                     /locus_tag="VWZ68_001196"
     CDS             complement(9408..10382)
                     /locus_tag="VWZ68_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEU9372223.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(10382..10816)
                     /locus_tag="VWZ68_001197"
     CDS             complement(10382..10816)
                     /locus_tag="VWZ68_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9372224.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(10910..11695)
                     /locus_tag="VWZ68_001198"
     CDS             complement(10910..11695)
                     /locus_tag="VWZ68_001198"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEU9372225.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            12064..13428
                     /locus_tag="VWZ68_001199"
     CDS             12064..13428
                     /locus_tag="VWZ68_001199"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEU9372226.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            13431..13802
                     /locus_tag="VWZ68_001200"
     CDS             13431..13802
                     /locus_tag="VWZ68_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEU9372227.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            14016..15290
                     /gene="serS"
                     /locus_tag="VWZ68_001201"
     CDS             14016..15290
                     /gene="serS"
                     /locus_tag="VWZ68_001201"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEU9372228.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILIK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDASVTIPEALRPYMGGAEVIKP"
     gene            complement(15315..16214)
                     /locus_tag="VWZ68_001202"
     CDS             complement(15315..16214)
                     /locus_tag="VWZ68_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEU9372229.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(16324..16872)
                     /locus_tag="VWZ68_001203"
     CDS             complement(16324..16872)
                     /locus_tag="VWZ68_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEU9372230.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(17090..18412)
                     /locus_tag="VWZ68_001204"
     CDS             complement(17090..18412)
                     /locus_tag="VWZ68_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEU9372231.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(18503..18591)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(18755..21091)
                     /locus_tag="VWZ68_001205"
     CDS             complement(18755..21091)
                     /locus_tag="VWZ68_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEU9372232.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRKVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(21195..21743)
                     /locus_tag="VWZ68_001206"
     CDS             complement(21195..21743)
                     /locus_tag="VWZ68_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEU9372233.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQIYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(21740..22042)
                     /gene="zapA"
                     /locus_tag="VWZ68_001207"
     CDS             complement(21740..22042)
                     /gene="zapA"
                     /locus_tag="VWZ68_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEU9372234.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            22129..23013
                     /locus_tag="VWZ68_001208"
     CDS             22129..23013
                     /locus_tag="VWZ68_001208"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEU9372235.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVASFV
                     TPDQHAFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISNPISLEE
                     KAEGKYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQG
                     LNFCAKLHFKNTEKAKNA"
     gene            23025..23639
                     /gene="lepB"
                     /locus_tag="VWZ68_001209"
     CDS             23025..23639
                     /gene="lepB"
                     /locus_tag="VWZ68_001209"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEU9372236.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            23767..26133
                     /locus_tag="VWZ68_001210"
     CDS             23767..26133
                     /locus_tag="VWZ68_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEU9372237.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLKTIQKHITTIEKELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSSISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(26181..27464)
                     /locus_tag="VWZ68_001211"
     CDS             complement(26181..27464)
                     /locus_tag="VWZ68_001211"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEU9372238.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(28308..29444)
                     /locus_tag="VWZ68_001212"
     CDS             complement(28308..29444)
                     /locus_tag="VWZ68_001212"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEU9372239.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQVLDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(29506..29943)
                     /locus_tag="VWZ68_001213"
     CDS             complement(29506..29943)
                     /locus_tag="VWZ68_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9372240.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(29945..31900)
                     /locus_tag="VWZ68_001214"
     CDS             complement(29945..31900)
                     /locus_tag="VWZ68_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU9372241.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(31924..33693)
                     /locus_tag="VWZ68_001215"
     CDS             complement(31924..33693)
                     /locus_tag="VWZ68_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEU9372242.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPIANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFFVA
                     ALILHADKSTEDSLEAAQEATQAAKAQSKGQLVSTSVDAVISTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGAFPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
BASE COUNT        10041 a         7624 c         6384 g         9795 t
ORIGIN      
        1 caacaataaa aagaaaaagt gtttgataga tatcaaacac ttttttcttt gcctcccact
       61 atctaaaaaa atgataatag atataattgt aaacaaaaat ccagataggt tttgcatgat
      121 tgagaaagtt aaaaaaacta tggcagagaa tcgttaatct cagattgtcg gtagaacgat
      181 aaacaagggc aaaaaagaaa ccaatcagac tataatataa taaactaatt ggatctctgt
      241 gagatagtat caaatggcta atcccaaaga tgatagcaga taggataaca tccaaatagt
      301 acttggacta gggaaagaag gtattcataa aataccctct atcaagagtc tcctcaaaaa
      361 caggaccgat gattacaggc aggacaaaag ataagatagt cgataaaaag gttggttgtc
      421 catttgaaaa aagcacggta aaatactcat catgaatatt cctatgatta atcaaatgag
      481 catagcgtgc ccaaaaatta ccgagaatct gataaaccac ataagttgca aataagtaga
      541 agacaaatga ccagttccag ctctttttct caaagataaa gagcatcttt ttctttttta
      601 acctccaaat taatagaagg aaacttccca ctaatcccat tgttaaaata agagaataga
      661 catcagctcc taaccctaaa atgatcgtca catacaatcc aattgtttgt ggtaaatagg
      721 tagatagtaa aataataagc aaaaatattc caaattgtct tagttttttt gtgtttctca
      781 tcgtactttt ttgaaagatt accctgctcg gaagccgtac ttccaagcat ctatataaga
      841 attaagtgcc ccttgcctca tatagggagc aaattctcta taatataacc atctactata
      901 tccatcttcc caaacagcaa gaccacctga agtttgctcc aagtcctcag ttgaaagaac
      961 tgtaaatgta tttgtacctg tcattgcaag taccttctta aaatagattg ttgtaggctc
     1021 acatttatag tatatttctt tttttgtcta ttttatagcc catctcctca actggcaatt
     1081 tttcgacctg aattacattt ttccataaaa aatgagacct ttctagtctc atttagtcat
     1141 tcttagtatt ttctaaatcg ttgatagcgt tcttccagca actcttctag cggtttttgt
     1201 gaaagtctag ccagctccgt ttggagttct tttttgacac tcttaatcag ttctttacta
     1261 gaaagtccta tttcagaaat caccttatcc accacgtcca tttctaacag ttcatgcgaa
     1321 gtgattttca tcagttctgc tgcttccatg gcgcgagtac cgtccttcca taaaatggaa
     1381 gcaaagcctt ctggactgag aatggcatag atagaatttt ccagcatcca gacacggtcc
     1441 gcgacagcta gagccagagc cccgcctgaa ccaccttcac cgataataat ggcgataata
     1501 ggaactttca ggtcactcat ttccatgaga ttgcgagcga tagcttcccc ttgaccacgt
     1561 tcttccgctc cgacaccagg ataagcacct gctgtattga taaaggtcac aactggacgg
     1621 ccaaatttct cagcatgttt catcaaccgc agtgcctttc ggtagccttc tggatgtggt
     1681 tggccaaaat tccgtttgag gttgtcttgc aaactcttgc ctttttggat accaaccact
     1741 gttacagctt gatctccaag ccaaccaata ccaccaacaa ctgcaccatc atcacgaaaa
     1801 gaacggtcac catgtaattg gataaattca tcaaaaatgc ctgtcgcaaa gtccaaggtt
     1861 gtcaagcgac tctgctcacg cgcttctctg actatttttg caatattcat ctaggactcc
     1921 ctccatgcaa tctgactagg ctagcaatcg tatctggtaa gtctcttctt ttgacaatag
     1981 catccacaaa gccatgttct aataggaatt ctgccttttg gaaatcctca ggcaagcttt
     2041 cacgaaccgt attttcaatc acacgacgcc cagcaaaacc aaccaagctc tgtggttcag
     2101 ccagaatgat atcgccttcc atagcgaaag aagctgtcac accaccagtc gttggatctg
     2161 tcaaaatggt caggtaaaag agaccagcat ttgaatgacg tttaaccgcc gcagagatct
     2221 tagccatctg catgagactc atgattcctt cctgcatacg ggctccacca gaggctgtga
     2281 ataggacaac tggcaatttt tcgacagtcg catactcaaa caaacgagtg attttttcac
     2341 ctacaaccgt acccatagaa gccatgataa agttagaatc cataatcccg agagccacag
     2401 tctgaccttt aataagagca gttcctgtca caacggcttc atgcagacct gttttttcac
     2461 gcatagatgc cagtttcttt tggtaaccag ggaaatgcaa gggatccttg ctttcaatcc
     2521 ctgtaaacaa ttctttgaag gttcccatat caatcgtcaa agccaagcgt tcttgggcag
     2581 aaatacgaaa ggtatagcta cagtgcggac agatacgttc acttcccaga tccttctgat
     2641 agatggtatg cttacagcct ggacactggg aaaataattc atctggaacc tctggcttag
     2701 cttgaggttt ttccctaacc gaacgattgg gattgattcg aatatactta tcttttttac
     2761 taaatagagc cattgattcc ccttttcggt ttaaactctt aaagtcattt tattcttttt
     2821 cttgatattt aggtaagaag gtttccatca agaaggaagt atcataatcc ccagcaatga
     2881 cattgcgatc tgaaatgagg tcaagctgga aatctgcatt ggtctgcact ccttcaatct
     2941 ctaattcata gagggcacgt tgcattttca tcaaggcgtc aaaacgattt tcgccgtgta
     3001 ctatgatttt ggcaatcata ctatcataat aaggcggaat ggtataacct ggataaactg
     3061 ctgaatccac gcgcaagcca actccaccac ttggcagata gagattagta atcttacctg
     3121 gacttggagc aaagttaaag gctgggtttt ctgcattgat acgacactcg atggcatgac
     3181 cgcgtaggac aatatcttct tgcttaacag acaaaggctg acctgccgca atgcaaatct
     3241 gttccttaac gatatcaaca cctgaaacaa actctgttac tggatgttct acctgaacac
     3301 gagtattcat ctccatgaaa tagaaattgc tacttgcttc atcaagaaga aattcaatgg
     3361 ttcctgcatt ctcatagcca acaaactctg ccgctcgaac agcagcagca cctatttcat
     3421 gacgcagcgt ttttccgatt gcaatcgagg gactttcttc caaaaccttt tggttattcc
     3481 tttgaagaga acaatcccgc tcacccaagt gaatcacatg tccatgctca tcacctagga
     3541 tttgaacctc aatgtgccga gctggataga taacccgttc tatgtacatg gcaccattgc
     3601 cataattggc cttggcctca ctagaggcag tttcaaaggc agaaacgagg tcatctggtt
     3661 tttcaacctt acgaatccct ttaccacctc cacctgctga agccttgagc ataacaggat
     3721 agccaatttt ttcagcaaca atcaaagctt cttcagagtt atgcacttct ccatctgaac
     3781 ctggtataac aggcacacct gctttaatca tctgagcacg cgcattgatc ttatccccca
     3841 tcatatccat aacatgacca gatggaccga taaacttgat acctacttct tcacacatgg
     3901 tcgcaaattt ggaattttca ctgagaaatc caaaaccagg gtgaatagct tctgcctcag
     3961 tcaagactgc agctgataga actgcattaa tattgagata agactctgtt gccttgccag
     4021 gaccaataca aactgcttca tctgccaaaa gcgtatgaag agcttcctta tcagcagttg
     4081 aataaaccgc taccgtcgca atccccaatt cacgtgccgc acggataata cgaaccgcaa
     4141 tttcaccacg attggcaatt aaaatttttc gaaacatgga gaacctcctt agttcccaat
     4201 tgcaaaagta aggataccac tggctgcaag cttgccatcc acttcagcct ttgcttcaac
     4261 cacagctatg gtgccacgac gttttacaaa agtcgctgtc ataaccaatt ggtcgcctgg
     4321 tacaacttgc ttcttgaact taaccttgtc cataccagcg taaaagacca gttttccttt
     4381 attttcaggt tttgataact ccaacacacc agcagtttgc gccaaggctt ccataatcag
     4441 aacacctggc ataactgggt attgaggaaa gtggccgtta aagaaaggtt cgttaatggt
     4501 cacatttttg atagcaacaa tggtatcctc gctcacttcc aagacacggt ccactagaag
     4561 cataggataa cggtggggaa gagcttcttt gatttcttga atatcgatca tttgatacgt
     4621 accaatcctt taccaaactc aaccatttct tcgttagaga cgagaatttc cgttaccaca
     4681 ccatccttag gagctgggat ttcattcatg actttcatgg cttcgataat taccaatgtt
     4741 tgaccttttt tgacactatc accaactgta acgaaggcag gtttatctgg tccagcagcc
     4801 aagtaaacca ctccaacaag tggactctct acaagatttc cctcagtagc cacacttgct
     4861 tcagctggag ctggaacttc ttctgctaca gtctctgctg gagcagatgt aggagctact
     4921 ggactcggtg ttgctagaac gggtgctgga gcgacttgag ttgcaacttc aggcacaggt
     4981 ctcgcttcat tcttgctaaa ctgcaactca tccgtcccat ttttataaga aaattctctc
     5041 aaacttgact ggtcaaattg agtcatcaag tctttaatat cgtttaaatt catacttatc
     5101 tattctccca acgtttgaaa gcaagaactg cattgtggcc tccaaaacca aaagtatttg
     5161 aaatagcgta tggaatttct ttctccaagc cttgtccata aacgacatta gcttcgatat
     5221 aatctgatac ttcacttgtc ccagctgtca ttggtacaaa gttatggcgc atagcttcga
     5281 tggtgacgat agcttctact gcacccgcag cccccagcaa atgtcctgta aaagacttgg
     5341 ttgatgatac aggtacttcc ttaccaagaa cagctacgat agctccactt tctccttttt
     5401 cattggcagg agttgacgtt ccgtgagcat tgacataggc tacttgctct ggagaaatct
     5461 cagcttcttc caaggctagt ttgatggcct tgatagctcc ctgaccttct ggatgtggag
     5521 aagtcatgtg gtaggcatca caagtatttc cgtaaccaac cacttcagcc aggatagtag
     5581 ctccacgttt ttcagcgtgt tcaagacttt ctaaaaccaa catccctgaa ccttcaccca
     5641 taacaaaccc attgcgatcc ttatcaaatg ggatcgaagc acgagttgga tcctctgtag
     5701 tagagagagc tgttaaggct tggaaaccag cgatggcaaa aggtgtgata gaagcttctg
     5761 ttcctcccac caacatcaca tcttggaaac caaacttaat ggagcggaag gcatccccaa
     5821 tcgcatcatt tgatgaagag caggcagtat tgatagattt acaaacaccg tttgcaccaa
     5881 aacgcatggc tacattccca gaagccatat ttggtaaagc ttttggaaga gtcattggtt
     5941 tgacacgttt gggtcctttt tcatgaaggc gaagtacctg atcttcaatt tccttgattc
     6001 caccaatacc agatgcaacg ataacaccaa aacgatccct attaagagcc tctacatcaa
     6061 gattggcatg atttacagcc tcttgggctg catacaaggc atataaagaa tagttatcaa
     6121 aacggttggt atcttttttt acaaagtatt tatcgaacgg aaaatcttgg atttctgccg
     6181 cattatgcac atcaaagtca ctatgatcaa attttgtaat gccaccaatg ccgattttcc
     6241 cagttgctaa actattccaa aattcttctg gtgtatttcc gattggagat gttactccat
     6301 aacctgttac cactactcga tttagtttca ttcttttcac ctctagcttt cgctacatac
     6361 ttaagccacc atcaatggca atcacttgac cagttagata atcttggcct gctaaaaata
     6421 ctgtcaaatc tgcaacctgc tctgcctgcc caaattcttt catcggaatc tgagctagtg
     6481 tagcttcctt aatcttatct gataagatag ctgtcatatc agactcaatc attcctggag
     6541 caatcacatt gactcgtata ttccgactag cgacctcgcg tgccacagac ttggtaaagc
     6601 caatcaagcc agccttagaa gcagcatagt tagcttgacc aatattcccc atcaaaccaa
     6661 caacactaga catattaatg atagcacctt ctctggcttt catcatcggt ttcaagactg
     6721 attgtgtcat attaaaggca ccagtcagat tgaccttgag cactttttca aaatctgctt
     6781 ctgtcatctt gagcataaga gtatcttggg taatccctgc attgttgacc aaaacatcta
     6841 ctgaacccag ttctgcaata gcttgatcaa tcatacgctt agcgtctgca aaatctgata
     6901 catctcctga aatgggaacc accttgatac catagtttga aaactcagcg agcaattctt
     6961 ctgagattgc cccacgactg tttaagacaa tgttggctcc tgcttgagca aacttgtggg
     7021 cgatggcaag accaattcca cgactcgaac ctgtaataaa gatattttta tgttctagtt
     7081 tcattttttt cctttcaaaa cttctactta ttttagtcta tttttctaaa agtgctacta
     7141 aactcgcttg atcttccaca tgagctaagt gagcagtttg atcaattttt ttaacaaaac
     7201 ctgacaagac tttccccggt ccaatctcga taaagttgct tatgcctgct tcttgcatga
     7261 ccccaatact ttcatagaaa cgaacgggtt ccttgacctg acgcgtcaag agctgagcaa
     7321 tgtcctcttt ttgcatcaca gcagcttctg tattgccgac taggggacaa gtaaaatctg
     7381 aaaaacttac ctgagctaga gtttcagcta gtttctggct agctggctca aggagagcgg
     7441 tgtgaaaggg acctgacacc ttaagaggaa tcaagcgttt ggcacctgct tcttgcaaaa
     7501 gttcaaccgc tcgatcaact gcaaccactt ctccagcaat gacgatttgt gcaggtgtgt
     7561 tatagttggc tggagtaacc actccaagtt cagaagcttt ttgacaggct tcttcaatga
     7621 cctctactgg cgtattgaga actgctacca tcttgccaga gtcagcagga gccgcttctt
     7681 ccatataggc tccacgctta gctaccaagg caaccgcatc ttcaaaatcc aaggcgccgc
     7741 ttgccaccaa ggcagagtat tctccaagag acaaaccagc aaccatatca ggctgatagc
     7801 ccttttcttg caataaacgg tagatagcaa ccgaagtcgc tagaatggct ggttgcgtat
     7861 agcgggtctg attgagtttg tcttcttccg tatcgatgag ataacgcaaa tcataaccta
     7921 gcacctgact cgctcgatca atcgtttctt taacaatcgg atactgatca tagaaatccc
     7981 gtcccatccc tagatactgg gcaccttgac cagcaaataa aaaggctgtt ttagtcattt
     8041 cttacaactc ctgtccagcg agaggcttct tcttgaattt tcttagcggc tccgtaatac
     8101 aaatctttta ggatttcttc agctgtttct tctttagaaa caagccctgc gatttgacct
     8161 gccatgacag agccaccctc cacatcaccg tgaacaactg ctttggctag ggcaccggct
     8221 cccatttgtt caaagatttc taaatcagga tcttcctgct taaaggcatc tttttcagcc
     8281 agttcaaaat ctctagtcaa ctgattttta atagcacgaa cagcatgacc aaagtgctga
     8341 gctgaaatcg tagtgtcaat atcccttgct tttaaaattt tctccttgta gtttggatgg
     8401 gcattcgact cttttgcaac tacaaaccgt gtccccacct gtacagcctc tgcacctagc
     8461 ataaagccag ccgcagcacc ttcaccatcc gcaattcctc ctgcagcaat aacaggaata
     8521 gatacagctg tggctacctg tcgcaccaag gtcatggttg ttaatttacc gatatgcccc
     8581 ccagcttcca ttccttctgc aataacagcg tctgcaccga ttttttccat gcgtttagct
     8641 aaagcgacac taggaacgac aggaataacg attatcccag cttcatggaa acgttccata
     8701 tacttgcttg gatttcctgc tcctgttgtg acaactttaa caccttcttc aataacgaga
     8761 tccacgatat cttccacaaa gggagataag agcatgatgt tgaccccaaa gggtttatca
     8821 gtcaatgatt tgattttatc aatattggcc ttgacaactt ctttcggggc atttccccca
     8881 ccgataattc ctaatcctcc agccttggaa acagcccctg ccaaatcacc atcagcaacc
     8941 caggccatcc ctccttggaa aataggatag tcaatcttca ataattctgt aatacgcgtt
     9001 ttcatagtgc ctccaacctt ccttgcttac gtaatagttc gatttcacca taatttgaca
     9061 gtcaaactat tacctaaaca agagggagtg ggtttctccc tactccttct actaatattc
     9121 tgcttatttt gcttgctctt caacgtaagc aaccaagtca ccaactgttt tcaagtcatt
     9181 ttctgcttcg atttggatat caaaagcatc ttcgatttct gagattactt ggaacaagtc
     9241 caatgaatct gcgtccaaat catcaaaagt tgattcaagt gttacttctg atgcgtcttt
     9301 tccaagttct tcaacgataa tttcttgtac tttttcaaat actgccatga taggactcct
     9361 ttaaaataaa tagttttttt ataacaatgt gttcaccaca tgattaccta aattgtaaga
     9421 atgagcgtgc cccaggtcaa gcctccaccg aagcctgata gaagaacagt ctggctacca
     9481 tctaaaggga tgagaccttg ttctacacac tctgaaagta aaatcgggat actggctgca
     9541 ctggtattgc catattccat catattggct ggaagtttgg ctcggtcaac accaattttt
     9601 ctagccatct tatccaaaat acggtcattg gcttgatgaa gtagcagata atccaagtct
     9661 gtcacctcta taggagattc atcaatagtc tgcttgatag acttggctac atctcgaatg
     9721 gcaaaatcaa agactgtgcg tccatccatc ttcaaaaatg aatctgcact ttcttgatct
     9781 gaaaatggag aatgcaaacc tgaatgccca taagttaaac actcgctgcg acttccatcg
     9841 ctattgagac tctcagctaa gaaatgctct tgctcgctag cttctaacaa gacaccacca
     9901 gcaccatctc caaacaacac agctgttgat cgatccgacc aatcgactgc cttagagagg
     9961 gtttcactac caatcaccaa gcctttttga aagcgaccag aagcgataaa cttttcagca
    10021 gttgaaagag caaatacaaa tccactgcaa gccgcggtta agtcaaaagc aaaggcttta
    10081 ttagcaccaa tattagcttg aacacgagca gctgtagagg gcatcatcga atctggagta
    10141 atggtagcta ggatgataaa atccagttct tctcctgtta ttccagcttt tgccatcagt
    10201 ttcttagcaa cctctgtagc caaatcactg gtagattctg ttcttgaaat atgcctttgt
    10261 cgtattcccg ttcgacttga aatccactca tcattggtat ccataatctg agccaagtcg
    10321 tgatttgtaa ccacttgctc tggcacataa tgagcaacct gacttatttt tgcaaaagcc
    10381 attatttcaa atcctccaaa aattggtaaa gattagtcaa gcctttaccc atgacagcaa
    10441 tttcttcctc gctcatgcca tcaataattt tttctaccat ggccttgtgg aagcgtttat
    10501 gcagtctatg aatcaagcga cccttctttg tcaaatgcag atgcaccaca cgacgatcct
    10561 gttctgaccg aactcgctca atgtagccct tacgctctaa attgttcaaa cttgtcgtaa
    10621 cagttccaag agttaccatc aactcttttg acacttgact tggagtcaca tctggagcct
    10681 taccgatgac atcaatcgta tgcatttctt tgatggagat atccttaaaa cgactacctc
    10741 tcaagttcac ttcctcaatt acaaggacat tgttaaatat agatgttaaa tattcattga
    10801 ttcgttggta gtccattttt catatccctc cttcttcaaa aaacttttac aatcaaaaca
    10861 tttgacagaa agaattatat caaaattcaa agaatgatgc aagtattttt tattttcctg
    10921 taaatttagg tcttcttctc tccgaatgag ctcgcactcc ttctttgaaa tcctctgttt
    10981 gagctaagga tttctgtagg ttcagttcta aagtagcgta accctgccag tctttaaatt
    11041 ggctctccca aaccaacttc ttaatggcag cataggaatt acttgaagca cgtcttaatt
    11101 ttttaagaag ctgttctctc gtcttttcaa gtttttcagc ttcagaaacg cggtaaacca
    11161 acccccattc tagggctttt tctgccgtta aagcctctcc tgtcatagct aattgagcag
    11221 cacgcgtcac accgatactg cggctcaaga gatgaattcc ccctgcatct ggagccaaac
    11281 caacaccaac aaaggcttgg ataaacttag ccttatccgt cgccaaacag aaatctgccg
    11341 caacagccat attcgctgcg gcacctgcaa cagcaccgtc aacttccatt aaaacaggtt
    11401 tggctatttg cttgatttta taagaaatcg tattgaccaa ctctgcgatt tttgtcaatg
    11461 atggaatatc atcctcatcc actgcccgct tcatctctac caaatctccc ccaactgaga
    11521 agaccttccc attggcattg attaagataa aatgcacagc tggattttct tctgccaaag
    11581 tcagagcttc taaaatctcc tcacacatgg gaatatgaaa accatttgcg acctcaggac
    11641 ggttcaaggt aaggattgcc aagtcctctt caagctgata aataatgtgt tccatcaggg
    11701 ctccttttta ttttataagc agtttatact cttcgaaaat ctcttcaaac cgcgtcagct
    11761 tccatctgca acctcaaaac agtattttga gctgacttcg tcagtcttat ttacaacctc
    11821 aaagcagtgc tttgagcagt ctgcggctag cttcctagtt tgctctttga tttcattgag
    11881 tgttaaatta tttcactgtc aaagtatatc ttttttagga gcagaaagca agaaaaaatc
    11941 gactgaaagt gtctcagccg ataagaaagg ctcgctttag gctagaaagc atcttatttt
    12001 cttcattgaa aaaagccttt ctttctgcta taatcgtata aaatacttac tttaggagtt
    12061 cttatgaaag ttgttaaatt tggaggtagt tctcttgcct ctgctagtca attagaaaaa
    12121 gttttaaaca tcgtcaaaag cgattcagag cgtcgttttg tagtcgtttc tgcgcctggt
    12181 aaacgcaatg ctgaagatac taaggttacg gatgccctga ttaaatacta ccgcgactat
    12241 gttgcgggta acgatattag caagagccaa agctggatta tcgaccgcta tgctgctatg
    12301 gttagtgaat tgggactaaa accagctgtg ctagaaaaaa tttctaaaag tattcacgcc
    12361 ttggccactc ttcctattga agaaaatgaa tttctctacg atactttcct agcagccggt
    12421 gaaaataaca atgccaaatt gattgctgcc tactttaacc aaaatggtat cgatgcacgc
    12481 tatatgcacc ctagagaagc tgggattgtg gtcacaagtg aacctggtca cgctcgcatc
    12541 attccatcaa gttatgacaa gattgaagaa ttgacaaaca ccaatgaagt ccttgtcatt
    12601 cctggtttct ttggtgtcac taaggaaaat caaatctgta ctttctcacg tggaggttct
    12661 gatattacag gttctatcat tgctgctggt gtcaaagctg acctctatga aaactttacg
    12721 gacgttgatg gtatctttgc agcccaccct ggtattatcc accaaccaca ctcgattcct
    12781 gagttgacct accgtgaaat gcgcgagttg gcctatgcag gcttctcagt ccttcatgac
    12841 gaggctcttc ttcctgccta ccgtggaaaa attcctctgg ttatcaagaa taccaacaac
    12901 cctgaccatc caggtactcg tatcgttcta aaacacagta atgatgaatt tccagttgtg
    12961 ggaattgctg gtgactcagg ctttgtcagc attaacatgt cgaaatacct catgaaccgt
    13021 gaggttggat ttggccgcaa ggttctgcaa atcctggaag aacttaacat cggttgggaa
    13081 catatgccaa caggtatcga cgatctttct atcattctcc gttctcgcca actaactccc
    13141 atcaaggaag aagaaatcct gcgtcagttg gttcaaaagg ctaaagtaga tcatgcagaa
    13201 atcgaacacg acctttctat cattatgatt gttggtgaaa aaatgaagag ccacatcgga
    13261 gtgactgcta ctgcgacacg cgctctatct gaaaacaaaa tcaacatcca gatgatgtct
    13321 caaggttcta gtgaagtttc tattatgttt gttgtcaata aagaccaaga gaaagcagca
    13381 attaaagccc tctacaatgc cttttttgga gaaagtaagg aagactaagc atggcccaat
    13441 cacttaacaa aacagtactc ctcagtacga caggcacttc ctacctctct atcgctggga
    13501 aagttgggaa attccttgtc ggagatcagg ctttggaatt ttacccagat gtcaatgtcg
    13561 aacaatttat ccagattcct tggagccata tcaatcagat tggagccaat gtcactggac
    13621 gcaaaatcag ccgccacttc gaagtcttta cagacaaagg aaaattcctc tttgcttcaa
    13681 aagactcagg tgccattctc aaaattgcac gcgaaaaact aggcaatgac aaggtcgtca
    13741 aacttccgac cctgattcag acaattagcc aaaaatttaa aaatctattt gcaaaaaagt
    13801 agaaacttta gtataatcat agcaacggat aagtaggtta tcttcttctt tcagaaagtc
    13861 tgcgggtact gcgagcagat aggagggata ggtgaaattc taccgttagt aacaattaca
    13921 tacacaatca agtgcacacc tgtgaagttg gatggaaccg tggccctgcc actccaacgt
    13981 tttgtcaggc gtgctttttt cataaaggag ttcttatgtt agatatcaaa cgtattcgta
    14041 cagattttga agctgtcgca gaaaaattag ctacacgtgg tgtagatgct gctgtcttga
    14101 atgaaatgaa agaaatcgat gctaaacgtc gtaacatctt gattaaggtt gaaactctca
    14161 aagcagaacg taacacagtt tctgctgaga ttgcccaagc taagcgcaac aaggaaaata
    14221 cagatgacaa gattgctgcc atgcaaaatc tatctgctga ggttaaagcc ttggatgctg
    14281 aattggcaga aatcgatgct aaattgacag aatttacaac gactcttcca aatatcccag
    14341 ctgacagcgt tcctgttggg gctgacgaag acgacaatgt ggaagttcgc cgttggggta
    14401 ctccacgcga gtttgacttc gaacctaaag ctcactggga tctcggtgaa gaccttggta
    14461 tccttgactg ggaacgcggt ggtaaggtaa caggcgctcg cttcctcttc tataaaggcc
    14521 tcggtgctcg tttggaacgt gctatctaca actttatgtt ggatgaacat ggaaaagaag
    14581 gctatactga agtcatcaca ccttacatag tcaaccatga ttctatgttt ggtactggtc
    14641 agtatccaaa atttaaggaa gatacttttg aactcagcga taccaacttt gtcttgattc
    14701 caactgctga agttcctctg acaaactact accgtgatga aatcttagac ggcaaagatc
    14761 ttccaatcta cttcactgcc atgagtccgt cattccgttc tgaggctggt tctgccggtc
    14821 gtgatacgcg tggcttgatc cgtttgcacc aattccacaa ggttgaaatg gtcaaatttg
    14881 ccaaaccaga agaatcttac gaagaattgg aaaaaatgac agccaacgct gaaaacattc
    14941 ttcaaaaact caaccttcca taccgtgtcg ttgctctctc tactggagat atgggcttct
    15001 cagctgcgaa gacttacgac ttggaagtgt ggattccagc acaaaacaat taccgtgaaa
    15061 tctcaagctg ttcaaacaca gaagatttcc aagcccgtcg tgcccaaatc cgttaccgtg
    15121 atgaagcaga tggcaaggtg aaactccttc ataccttgaa cggttctgga cttgcagttg
    15181 gacgtacagt ggctgcaatt cttgaaaatt accaaaatga agatgcttct gtgaccatcc
    15241 cagaagcact tcgtccatac atgggtggag ctgaagtcat caaaccataa aaaataaggt
    15301 ttagctattt ctagctagac cttttttcgt aaccaaatca gataagcacc tagtacaaag
    15361 aataaaatag ttaggcatat aatggtttca gccaatacca ggtaatccag aaatggaagt
    15421 ttcaaaattc cctgagccat cttgagcgag gtcgctgtga taatggttgg gaaggtgagg
    15481 gctgagaagg ctggttgaaa accttgtttt aaaatgttgg gcagacgagt taaaacaaag
    15541 aaaaagaagg attgagaagc caaaatcatg acaatcaaga cccaagtcgg caggctggtt
    15601 cctcctactc gaactagaga agccaagagt agagagaaag gagcacagta gattccttct
    15661 tgtccaagca aggctagtgg gagtggatgt ttctttaaat cgctataaat aaggggatag
    15721 agatagaagg tcaagagaaa accaaaactc aaggtcgcat aggcaatttc gataatacct
    15781 accagaggat aggtcaaggc agccactgct atccccacat agagaaccgt ccaacttgga
    15841 gtggcatgaa ccctccgccc tggacaagca aacttgatgg taaaaccagc aatcaaggtc
    15901 aaatccaaga gaaatgaaaa ccaccaaatc ccttgtgcta ccaaaggaag ataagagaat
    15961 acgcgaaaga cataggtcga taaaatcatc ccagccatag gaaaggttgc cattcctgac
    16021 aaaagagggg gcttggtcaa ttcttgcttg gtttctttcc aattaaagag atgcagaatt
    16081 agaaagtaaa tccataaaac caaaccagtc agactaaaaa gatgggatag aaccggcaac
    16141 gtatctaaaa taagatttcc agctcctgcc aaacctagca aacaacctga aaatactaag
    16201 gggagttttt tcatcctaac ctccaataat catgttagtt tcagtataac ataaaagcgc
    16261 ttaaatgagg atttaaaaaa acgaagtccg cttatttcag acttcatttt actcagatat
    16321 gaattaggca taaggttgca attctggatt aattggtgta ttagctaagt tgttggcata
    16381 gttacagagg attgctaggc tgacaccaaa aaccacatcc aaggcatttt gttgagtgta
    16441 gccagcttct aaaaactcag acaaggcttc atctcctaca cgacccttgg tattgataac
    16501 tgccaaggta aacttagcta gggtatccaa tttaggatct gtttcaattg gagtacgatt
    16561 gcgaagagct tgaatcaagt catcattcat ctggatttgt ttgatggaaa aggctgtgtg
    16621 acctgcgaca cagaaggcac aaccattggt cacggctgcc gtgatttgca ccacttcacg
    16681 ctcaacgggt gtcaggctgt tgcgacggtg gatagatgag acaatttgat aggcttctaa
    16741 aacagtcggg gcattggcca agagaccgat taggttggga atatagccat tgttgtcttt
    16801 ttctactgtt tcaagaattt ctttcacttc tgctggtgct gactctactg tatggatagt
    16861 aaatgttgtc ataagatacc tcttttctta ttattgacac taatattatt ggaaaatctt
    16921 ataaaatcct gattcctaag tttatctaag ataaagcttt attctctcat aagattttcg
    16981 ttgttatatt agtttatcac acttccaatc acttgcataa tatatattat atatcaggct
    17041 gataaaaatt atttataggc aaaaaaatca cacgagctgt gtgattccat tatttgtcaa
    17101 aatacttttt agtttcagca ataacgactg gcgacaagac caagagggca atcaagtttg
    17161 gcagagccat caaggcgtta acgatatctg cgataatcca gaccatatcc aactcgataa
    17221 atcctcctaa caagaccatg agcacaaaaa ccacacggta gagccagata aagcgaaccc
    17281 caaagaggaa ctcaaaacag cgttctccgt aatagttcca acctagaatc gttgtaaagg
    17341 caaaaagtac aaggaagatg gtcaagaggg caggcccaaa gtgtgaaaag actgttgaga
    17401 aagctgactg agtcaaggca accccattca agtcaccact ccaaactcca gttaccaaga
    17461 tggtcaaacc agttagagta caaatgatga gggtatcaat aaaggttcct gtcatggaaa
    17521 tcaaaccttg ctctactggt tcatttgtct tggcagctgc agctgcaata ggagcagaac
    17581 ccagaccaga ttcgtttgag aacacaccac gcgccacacc attttgaata gccatccgaa
    17641 cgctagcacc agcaaatcca cctaccgcag caaggggact aaaagctgag gtaaagacta
    17701 aagcgattgt gccagggatt tttccgatat taaagaaaat aactgtaaga gttcctaaga
    17761 tataaatgat ggccataaaa ggaacaacag tagttgaaac cttagaaata gacttgagtc
    17821 caccaaagac tgcaatcgct acaaagacag acaagacgag agctgtgatg gctggcgaaa
    17881 tcgtcgttgt attttggata gattctgcaa tcgagttgac ttgggtgaag gttccgattc
    17941 ccaagagagc aaccaatact cctgctactg caaacaaaac agcaagtggt cgccactttt
    18001 ctcccatccc tagaaggata taatgcatgg gacctcccgc tactgcacca tggtcgtcct
    18061 tggtgcggta tttgatggcc aagagtcctt ccgcatactt ggtagccatt ccaaagaaag
    18121 ccgccatcca catccaaaat agagctcctg gtccaccaac cttgatagcc gtcgcaactc
    18181 ctatgatatt tcctgttcca acagttgatg ccaaggctgt acacagagct gcaaaactgg
    18241 atacatcacc atgtccctta tcctggataa aaataagctg aaaagccttg ggcagacgca
    18301 aaacctgcaa gagtcctagc cgaatagtta ggtaaatccc tgttccgacc aataaaatca
    18361 agaggggcgg tccccaagca aaagcatcga ttgatttaag caattctaac atttccttct
    18421 cctatcgttt caaccccaaa agaaagagca catgcaagat acatgtactc tggaatgctt
    18481 agataaatgc taaaaagcgg tctatcctag ctctgtcctt ttacctgaga gtttgagcag
    18541 ttgcctgcct tgccccttcg gtgcctttac ggtctctcca gagttccgtc catttacagt
    18601 catggaaaat caaacgattc cccacttcta ttaaacttca ttcggtgttg gtatttaatt
    18661 gattctaatt ttacaaaaaa tgttggcttt tgtcaatgtg tttattagta aaaattagtt
    18721 caacagtttt tactttataa agtccagaat actgctatcc tttaaaagtg acaatagtcg
    18781 caccactgcc tccagcattt tgtggggcat agccgaaact cttgacatgt ttgtttcttt
    18841 gcaagtattt ggtaactcct tcacggatga ctcctgttcc gataccatgg atgatatcaa
    18901 cttgagccat attgttaagc aaggcttggt cgatgaaggt atctagctca ttcatggctt
    18961 cttcatagcg cttgcctcga agatccagtc tagcttgagg tcctcgccca gaagttcgtt
    19021 tcacaacatt gacctgtttc ttcttgactg gtttttcttg ctgggcttga acaagatcaa
    19081 actctttctc ttccaaggtc atcttaatca agccaacttg ggcttcccag cggccgtcct
    19141 tgagttgact ggtcaaggta ccacgctgac cataactgag aaccacgata tcatctccca
    19201 cctttggagc tcgttttttc ttggcctttt gaaggacctt gtttttagac aagtccactt
    19261 tttcaggagc caattttttc aacttggcct tggcttcaat gatttcgtgg ggcttgagtt
    19321 gggatttact gtggagattt ttgagaatct ggtcactttc acttagggcc atatccacaa
    19381 tctcagcagc ctgttcacgc gccttgttaa gctcggtttc cttttcacga ttaagctcgt
    19441 tgtagagttt ttttagcgca cggttcatct tgagattttc ttgctccacc tcacggatat
    19501 tgtccaagcg tttgcggctt tccagcgtct gctcttctaa ttgctcaatg atacgattga
    19561 cgtcattgtc ctgatcgatc tgctgactgg catctcctac gataacttca gataggccta
    19621 gacgtttggc aatttcaaag gcattacttc ggccaggaac accctgcata aagcgatagg
    19681 tcgggcgaag agttgcagta tcaaactcca tactggcatt ttgcacaaag gctgtctcaa
    19741 taccgtaggc cttgagttct ggatagtggg tcgtcgccat ggtcttgatt tgacgcaggc
    19801 gaaggtcctc cagaatagcc atggcaaggg ctgctccctc ttggggatca gtaccagccc
    19861 ccaactcatc caaaagtaag agtgaatgtt ggttgacctt gccaagaata tccacgatat
    19921 tggtcatatg gctagagaag gtagacaagc tctgctcaat agactgctca tctccaatat
    19981 cagcaaaaat ttcttcaaaa ataccaacac gacttccctt gtctgctaaa atcggcaatc
    20041 ctgactgggc catgacctgt gtcaagccca gagttttgag catgatggtc ttcccacctg
    20101 tattgggacc tgtaatgaca atagctgtta aatcttgacc aaaatagaca tcatttgcga
    20161 cggcattttt gaccaaagga tggcagacat ggagcagttg aatctcttga ttttctgaca
    20221 gctgaggcac gactgcttgt ctttcttgga taaatcgaac cttggcacga atcaagtcca
    20281 gatgaccgat aatccaagca tcattagcaa tctcagccgc atgagggcgg acacgctcag
    20341 aaatttcttg gagaatgcga agcatttcat agcgctcatc tgctcgcaga ctagcaattt
    20401 cttcgctcag tttgactacc tcacggggtt cgatatagac ggtgtttcca ctagcagaaa
    20461 tatcatgaac gacacctgca atcttattgc ggtaggtgtt tttgactggt aaaaccttac
    20521 ggccatttct gctagcaaca attccttccg tcaacatctg cgctttttgc ttgagcaagt
    20581 cttgtaaaac atcgcgtacc tgactctcgc tatcatgtat ttttcgacgg attcgcgcca
    20641 attcttcact ggcaaaattt tcaatgaaac ccgcatcatt aaaggcctga agatttcctt
    20701 gtaattgcgg aaaatcatgt aatttctcaa accaaagggc taattcttcc aagctgacat
    20761 tttccagatt ggcgtaaaaa ctttgaagtt ctcggctggc aagaagcacg cgtttcaaga
    20821 gtaggaactc ctcgatattg agatccgctc ccatctccaa cctcttgcag actcctgcaa
    20881 tttccttagt tgagagaata gtaaaatgcg gttgctcgac gaaaagagcc tgcatttcct
    20941 tcatctcagc aaaagcctgt ttgattttat ctgctttggc agtcggagcc agttgtctca
    21001 attgctccaa gccctgctcg gtcaacaaat gaggctcaaa caaggccttg accttatcga
    21061 actctaatgt ttctaatatt ttcttattca tctttatttc cttgtctttg aatgtctagg
    21121 tgtggtaact ttttacattc tgatagattc aagtcaaatc tgtaaacaaa gggctaggaa
    21181 aactcctgcc ctttttatcc gattaaattt gtcacccaga tttgtttgag ccaactggtt
    21241 gttatcggta tgctctggat gatgtgtttt gcgacgatac tcttttcaag aggattttgt
    21301 ataactgcca tggggatggt cgccaagatt gtcaaggcca tttgcaagac aaataaggtc
    21361 accaacatgg acaagatacc tgctgaaact tggaacaact taccacccag ttttttgcta
    21421 ggaatcaagt gtaagagaag accaagcaaa cgaccaatgc tatagacaat cccaaataca
    21481 agcaagtagc cgatacctgc ataaaagacc ttatccagct gaaagagttg atccgatggg
    21541 aaaaagaaag tcccctgacc ttcctgcgaa tttgcataag ggagcaataa atggaattgc
    21601 tctccaagcc ccttataaaa ctggccagcc ataaaagccg atgccatggc tgaaatcagg
    21661 taataaatct gtaagagcag gcctctccga tagccgatat aaaatcccca aaccaagacc
    21721 aatagaagaa ggaatgaaat cataaggaat cctcaatctt gctctgttct tgcttacaag
    21781 tcacaagctt gtgacggagt tcttctagct cttgctcctt atcgtcaaat tcaatctcac
    21841 ggctgagctg agttgataaa cagttgactg ccaacaaaag agcgattgtt tcatcatctg
    21901 cgctaggcat ttgttcttta attgcttggt atttttctgt cgcaacctta gcgatttcct
    21961 ccataaaaag gttatcatgt tcacttgtca aggttaacga ttttttcccg aatgtaaatt
    22021 tgaatcgatt tagatttgcc ataaaattca cctcacgata ttataccaaa attcgctaat
    22081 tttgtcagtt tttacaaatt ttactgcttt tgtggtacaa tagaaactat ggcaagtatc
    22141 acactcacac caagcgaaaa ggatattcag gcttttcttg aacactatca aaccagtctg
    22201 gctcctagca agaatcccta tatccgctac tttttgaaac tacctcaagc aacggtttct
    22261 atctatactt ctggaaaaat cttgcttcag ggtgaagggg ctgaaaaata cgccagtttc
    22321 tttggctatc aagctgtaga gcaaaccagc ggacaaaatc ttcctttgat tgggacagat
    22381 gaggtaggga atggttccta ctttggtggg cttgcagttg tggcttcctt tgtcacacct
    22441 gaccagcatg ccttcttacg aaaactcggt gtgggagatt ctaagactct gaccgaccaa
    22501 aagattcgtc agattgctcc tattctcaag gaaaaaattc agcaccaggc actccttctc
    22561 tcacccagca agtacaacga ggtcatcgga gaccgctaca atgctgtttc ggttaaggtt
    22621 gccctccata atcaggctat ctatctcctc cttcaaaaag gtgttcagcc tgagaaaatt
    22681 gtgattgatg cctttaccag tgctaaaaat tatgacaagt acttggcaca agagaccaat
    22741 cgtttcagca atcctatcag caatcctatc agcttagaag aaaaggctga gggcaaatac
    22801 ttggctgtcg cagtttcttc tgtcattgcg cgtgatctct ttctggaaaa tcttgaaaat
    22861 ttgggacgag aactgggtta tcagcttcca agtggagctg gaacggcttc tgacaaggtg
    22921 gctagccaga ttttgcaagc ctatggtatg cagggactca acttctgcgc caaattgcac
    22981 tttaaaaata ctgaaaaagc gaaaaacgct tagaaaggta agttatgaat ttatttaaaa
    23041 atttcttaaa agagtgggga ttattcctcc tgattctgtc attactagct ttgagccgta
    23101 tctttttttg gagcaatgtt cgcgtagaag gacattccat ggatccgacc ctagcggatg
    23161 gtgaaatcct ctttgttgtt aagcacctcc ctattgaccg ttttgatatc gtggtggccc
    23221 atgaggaaga tggcaataag gacattgtca aacgtgtcat cggaatgcct ggcgatacca
    23281 tccgttacga aaatgataaa ctttacatca atgacaaaga aacggacgag ccttatctag
    23341 cagactatat caaacgcttc aaggatgaca aactccaaag cacttactca ggcaagggct
    23401 ttgaaggaaa taaaggaact ttctttagaa gtatcgctca aaaagcccaa gccttcacag
    23461 ttgatgtcaa ctacaacacc aactttagct ttactgttcc agaaggagaa taccttctcc
    23521 tcggagatga ccgcttggtt tcgagcgaca gccgccacgt aggtaccttc aaagcaaaag
    23581 atatcacagg ggaagctaaa ttccgcttct ggccaatcac ccgtatcgga acattttaag
    23641 agacctaaga ggccgagaat caccaatctc agcctcttct tctatcgtga gaaaatgatt
    23701 ggtaactatc taaacttacc agaacagaaa cacctcaact ctcacctatt catgcaaagg
    23761 aattttatgg aagtttattt ttcaggaacc attgaacgga ttatttttga aaatcccagc
    23821 aatttttatc gcatcctcct cctagaaatc gacgatacgg acgcagagga ttttgatgat
    23881 tttgaaatca ttgtcacagg aaccatggct gatgtaattg agggcgaaga ctatactttt
    23941 tgggggcaaa ttgtccagca ctccaagtat ggagaacaac tgcaaatcag tcgttatgat
    24001 cgcgcaaaac caactagtaa gggcttggtc aagtactttt caagtagcca tttcaagggg
    24061 attggtctca agacagctca gaaaatcgtg gatacctatg gcgaaaatac cattgacgaa
    24121 attttgcaac acccagaaaa gttagaaggc atcgcaggac tctctgccaa aaatcgcgag
    24181 gctttcgtct ccactctccg tctcaactac ggaacggaga tggttttggc caaactagcc
    24241 aactacggca ttcccaacaa actagccttt cagattcaag acttttacaa ggaagaaacc
    24301 cttgatgtgg ttgaaaatta tccctaccag ctggttgagg atatcaaggg tttgggcttt
    24361 accattgctg accaactagc tgaggaacta ggcatcgaaa gtcaggctcc tgaacgcttc
    24421 cgcgccggtc tagttcacag tctttttcag gcctgtatgg aaacagggga cacctatgtt
    24481 gaagcacggg atttgctgga acaaaccctt actctccttg agtcttcccg tcccgtggaa
    24541 ctagacccca gccaagttgc ccaagagctc tcctacctga tcgaagaaga caaggttcag
    24601 cagattgata ccaagatctt tgacaacagc ctctttttcg ctgaggaagg catccgcagt
    24661 cacttggttc gtatccttga aaaaggaaaa cagaagagtc atgatttaaa aaccattcaa
    24721 aaacatatca ctactatcga gaaagagctt ggaattgagt atgataacat tcaaaaacag
    24781 gctatctgtg atgctatcca gaataaggtc tttatcctga caggtggacc tggtactggt
    24841 aagacaactg ttatcaatgg gatcatcgct gtttacgccc tgttagaggg acttgacctc
    24901 aggaagaaaa gcaacctgcc cattcttctt gctgctccaa ctggtcgagc tgctcgtcgc
    24961 atgaatgaat tgacaggttt gcctagcgcg accatacacc gccacttggg aatgacaggt
    25021 gacgatgata ccagtcatct ggaagattac ctagatgctg actttatcat cgtggatgaa
    25081 ttctctatgg tggatacttg gctggccaat caactcttct ccagtatctc ttctaacagt
    25141 aagatcctca tcgtaggtga cagtgatcag ctaccttctg tcagtcctgg acaggttcta
    25201 gcggatctgc ttcatattcc tttgattcct cagactcgct tggaaaaaat ttatcgacaa
    25261 agcgaagaat caaccatcgt caccctagct agtcagattc gacagggcat cttgccagct
    25321 gatttcaccc aaaaaaaagc tgaccgttcc tactttgaaa ttgctagtgg ccatattcct
    25381 gccaccattg aaaaaatctt aggtgccgcc ctcagaaatg gtattcctgc ccgtgatatc
    25441 caagttctgg ctcctatgta ccgagggacg gcagggattg atgctatcaa tcagctcatg
    25501 caagacctgc tcaatccccc acaaaaagat caactcagtt ttgaagctcc tcagtgccac
    25561 tatcgtaagg gagacaaggt cattcatttg gttaacgatg ctgaaatcaa tgtctttaat
    25621 ggggatttag gagctatcac agacctgatt cctggtaaat acaccgaatc gaaacaagac
    25681 gagattgtca ttgattttga tggtaatgaa gtctcttacc cccgtaacga atggtacaag
    25741 attcgcttgg cctatgccat gagtattcat aagtctcagg gaagtgagtt cccagttgtc
    25801 atcctaccga ttactagtgc tagccgacgt atgctggagc gaaatctcat ctacacagcc
    25861 attacacgtg ccaaaagcaa actcatctta ctaggcgaat tacaagcctt cgactatgct
    25921 acccaacaca tcggaactgc ccgaaaaacc tatctgattg aacgcttcag tgatctactg
    25981 gagaatgttg aagaaaagca acaagctgtc tctgaaacag tcacatcaag tgcctctgaa
    26041 caatcctaca tcctaaccga agaaaactgg gacagcattc cagccatgat tgggattaca
    26101 gacacagacc tcaaagagat ttttggaaaa tagtacatca gaaaacccac caattcaggt
    26161 gggttttctg tttattaaga ttattttact gttgctgtgc ttgtgatcaa ttcaacagct
    26221 tttttgatag tgatatcatg tttcaacatg tcagctgaaa gcaagttttg aacttgtgca
    26281 acttccatgt tgtagtctgc tgccaattgc tcaacttctt tttggatttc ttcttctgaa
    26341 gcatcaaatc cttcagcttt ggcaactgct tcgataacaa ggttagtctt agtacgtgac
    26401 tcagcttctg cttggtattg gttgtgaagg tcttcttgag tagttccagt gatttggaag
    26461 tacatgtcag ggttgatccc ttgacgttgc aagttcccaa ggaattcatt tactgaacgg
    26521 tgaacttctt catggatcat ttcttctgga agttctacga tttcagcgtt ttctacagct
    26581 gtatcaattg ctgcaccttc aactgcatct ttgtaagctt cttctttagc agcagccaat
    26641 tctttgcggt atttttcttt caagtcagca agtgtttcaa cttcttcatc aatgtctttt
    26701 gcaagttcat cgtcaagagc tggaacttct ttagctttta cttcgtggat agttgtcacg
    26761 aatttagctt ctttacctgc aaggtcttct gcttggtagt cttctgggaa tgttacgata
    26821 acatcaacgg tttcgccagc tgagtgacct accaattggt cttcgaaacc agggatgaat
    26881 tgacctgaac caagtccaag tgagaagttt tcaccttttc caccgtcaaa ttcaacaccg
    26941 tcgatagaac caacgaagtc gatcacaaca gtgtcgccgt tttcagcagc agcttccttg
    27001 ataaccaatt cagccaggtt gttgcgttcg cgttcgatac gctcttcaac atcagcgtca
    27061 gttacttctt tttctacatc aactgatact tcaaggtttt tgtagtcacc caattttact
    27121 tcaggttttg taacgacttc agcagcgata acccagtctt gacctttttc cattgaagtt
    27181 acgtcaattt ttggttgggc aaccacttca agaccagctt cttttacagc tgcttcataa
    27241 gcgtttggca aaagagcgtt cataacgtct tggtaaagtg attcttcacc aaatttttta
    27301 tcgaagatag gacgtggaag gtgaccttta cggaaacctg gaacattaag agatttcttc
    27361 actgacttga agacacggtc caattctggt ttgatttggt cttgagagat agtgaaagtc
    27421 aagacaccac ggtttgtttc tttgttttca aatgatacag acattctgtc atttctcctt
    27481 aaaatttttt aaatacagtc tattataaca ttttctataa ataaaatcta gactaatgca
    27541 gccaattata gacaacaagc ctttttccta actaaaacac tcataaagta tagacaattt
    27601 tagactactt tggatatctt ttggttagtc attttccaaa actaatttat ctaatttttc
    27661 agttatatag tagattgaaa ctagaatagt acacctctac ttctaaaaca tttttagaaa
    27721 tcgctttgac tgtcctgatc gatttgtcct gttcttgttt cattttacta tatagatcgc
    27781 attcgaaaga attcgttcca aaattgcttg gttcgttctt ctcttggacg actaaagaat
    27841 tgatgggcat tatttttttc aacaattttc ccaccgtcca taaaaataac atgatgggct
    27901 acatctctag caaaacctat ctcataaagc tgatcaaaaa ctcaatctga ggagaaaatc
    27961 caataaggct ttccataata aaggacatcc tatcaagatt tttgaacacc cgataggctg
    28021 cctttttccg attttgaaga ctttttgtcc agcttctttt accttataaa taacaacaaa
    28081 aatcaaagac aagctagaaa gattaccgca gataactcaa acagtgtttt gaggttgcag
    28141 ataagactga cggagtcagc tcaaagcact gctttgaggt tgcagataag actgacggag
    28201 tcagctcaaa gcactgcttt gaggttgtag atagaactga cgaagtcagt aacatatgcc
    28261 taagacaaag cgatgctaac ctgatttgaa gagattttcg aaaaatatta aatatactct
    28321 acaatttgct caatcaattc ttggtcgtct aaacctgtaa cttgtataac aacatctttg
    28381 actgattgtt tagccaacaa ttcacctaat cgaatacttt cttcatcatt tacatcgcga
    28441 tagtcaaagg catagccaac tgttttaagt aggtttttat atgacaaact gagttctttc
    28501 aattcacgta tcggccggat gaatcgttca ttatagccta attttcggat tggagtacga
    28561 gctacgcgac taacctcgtc cactatgaaa gggttttcaa accgttctat aatgactttg
    28621 tgataattct ccaattcttt tttatcaaag ttccatttgg caatcaagag actccgaatt
    28681 tcagctaata cagattcaat ccgagattta atattaggat tttgaagagc ttccaaaatt
    28741 gtcttggcac cataatgcgc accaatgtaa gctgaagttg catgtccaga attgactgaa
    28801 aaaagttttc gctcaataaa gggttctaaa tcttcttcat aatgcacatc ttttagacgt
    28861 aaatctggat ttttaagacg cttggtttcc acgacccatt cattaaaggg ctcgaccaca
    28921 acaaaaaggg aatcttcgtg actttgtgct ggaacaatcc tgtctactgc agcatttgga
    28981 aaacctatgt agttatcagc aaatgtcaaa ccttccggac ttaaatattt cttgacttct
    29041 tgataaagaa attgagaccc gccaatcata ttttcacagg ccataacatc caatacctgt
    29101 gtattccctg caactcggcg agcttcgatt cctttggcta gaagttcagc gataaaaggg
    29161 agtatattag gtccgattgc agtagtaata atatccgtct tttgaatcgc ttcaatgact
    29221 tgctcaggat gttctttgct attaattcca gccacattag ttacttctat acgagactgt
    29281 cctttctgtg caatttcaat ttcatacttg cccttttcat ttagagcatg aattatctga
    29341 ttattgacat ccacaaaatc aatatggaaa ccatttttaa atagaatttc acctataaaa
    29401 ccacgaccga tattaccggc accaaaatga acagaatgtt tcattcaatt tctccttttc
    29461 ctatttgagg gacatatata ctagatggca aatgacgaaa ttcaattatt caacagcatc
    29521 aaataagcgc aatacttcct cttttgactg agcatcggct aatttaagaa cattatctac
    29581 atctgcacag aagatagaaa ttttctgaat aatttctaag tgttcattac caataccagc
    29641 aataccaaaa agaaccgttg ccacttgagg gttagataca ttcccaaaat caacccctct
    29701 agggacttga acgactgtaa taccagactt gaggacatcc ttttttgctg catctgttcc
    29761 atgcggtatt gcgataaagt tacccatgta aacagatagc tctttatctc gctcaatcat
    29821 ggcttcaata tagtcttcat taacatatcc accctcataa agaacttgcc cacaataaca
    29881 aatagcttcc tccttgttag aaaattgttt attaagctta atcaaatgtt tttcaagttt
    29941 catattagtt ctccaatttc ttaatttttt cgttaaaaat agtatttagc atctgataaa
    30001 taatggattg atttcccgtc ttgtaaatct ctgtataaag atgattttca ataatcgact
    30061 gactaatagc tgtcattaaa tctctcgctt cctcgctagc ttctttagac attagcatta
    30121 gcagacacct tttgacctct tcttcctctc gtttcattga caatgcggag ataggtagtt
    30181 tgagttcaaa catagtaaaa ctatttgttg ttactttgct agactgacta tgtaaaagca
    30241 ccagaccagt attaggaata gccataggac tattctggaa gtgagataac aattttcttg
    30301 ttaggtaatc tctgtcactc acattcttct gatattggat gatttgttct accgtgtgct
    30361 caaatgattg attattctcc aattgaacca actcgaattg actcaaaagc tgactactag
    30421 atattaaata atcttgcaag tcataacttt tctctggagc gatagcatca cgcgcgacaa
    30481 ttgtacgatg tgcctgtaca tactgaagtc gttcctgtaa ttcaagcaat tctttgacgg
    30541 ttggaaaact agaaattaca tcgatttcct gattagtcag cggcttggta gataaaatat
    30601 aatcatactg actgagatca atactgtggt aatctactag agactgaata tctatcaact
    30661 ctacaaaagg agcaacactc ttaattttac tgactaataa atctctagtg acccgacgtt
    30721 catccgttaa aagcaaaaca cggactggat aaatctctgg actacggcct aagctagaga
    30781 taaaatgtag ggcaatcatg ccatactcat actctgtatg aagatatttc ggaaaaatat
    30841 cattcactaa aagactgatg actgtataaa gaaatttatt cctttcaact aaaatctgga
    30901 cagattctgg caaattttca ccctgaaaaa ggatagggac gcctaaactg agccgaatat
    30961 gatggaaaag aaaattgaat aaaaccttgt ccttaaaaaa gtcaatcttg gtatacatgg
    31021 aaaccgtatc aatcagattt gaaatattgt agaaaaattc accatcaaat ttctccgtaa
    31081 agagcggatt gtcctgacgt ttaatgatta attcatccaa gatgctcgca aaatagataa
    31141 tttcctgaat actataaaat tgtgcagtct gcttagagta agcttgaaaa attttttgag
    31201 aaatttccaa agcctgctta ctagtattag gtgaattttc aatgttttgc tcctgaccta
    31261 taagagataa caagatcgca aaaaacatct tcatcctagc atccatatct ggaaaacctg
    31321 acagttgctt attaacaatc tgactggcca gcctagttct atctgcttct aaaatatcaa
    31381 agctcccaaa attaccggtt gaaaaatctg ctactgagat acagtttgtc agtaaaatag
    31441 ccaaaaatct tctcttacca actgaatcac cagaaatccg ataacctttt tgtcgttcaa
    31501 ttttcagatc aaagtctaaa agacgcttat caatatctga aatatcctga ataatagtta
    31561 cattactgac tttcgtgcac tcttgcaatg cttcattggt gacaaaacca ctctcagtca
    31621 gaaggcgata ggtaatcaac tcttgtcttt cttggggact atactcaact aacacttcaa
    31681 gttctgtcgg caaatcatcc aactctccag tcaaaatata gtatttccca tgcttcgtta
    31741 tttcgattcc atattgctcc atgctatctg tcaaatctga taaagttcga taaattgttc
    31801 tagatgaaac ctgtaagatt tcagtcatat cttgcattga aagcttccct acatgtagga
    31861 aagccttcaa taattgttct tctcgtttgg ttaatagcat tcgtaattta gaaacctcta
    31921 gttctatttg tacattctag cagccatttt gtcatattct ggtgttgtta ctaaactatc
    31981 cacaataaga aattgagaat tcggtgctgc ttgctgcact tctgcctgta aagaaatagt
    32041 tgttacaatc attatgtttt tagaattaaa ttcacctaat tctgaaattt tggcagtaga
    32101 aactggaata cgaatattct tgtttctaaa gatagcccga atcgtttcac agcccatagt
    32161 tgcagttccc tgtgctttac cataagcaac tactacagca tcaatatggt taaggtcaat
    32221 ttcctgacta tctactggtg ctgaagttgg tatatctcct tcaatttctg ctattggaaa
    32281 agctcctgtt aatgaagcta caatttcatc ataacgaggg gacgctaaga aattatcaac
    32341 agaaacatga atagcacttg gactcttgtc tttagctctt ggtgtcagtt cttcctgagt
    32401 aacaattaat gtttttggtg tatcaagcaa atttgagatt gcctgattag atactggaat
    32461 ctctagacct gcttttttaa ccttatctcg aagaatacta gctcccatag cagagcttcc
    32521 cataccagca tcgcaggcga aaatgatttt ttccactgag tctgtcgaaa taactgcatc
    32581 aacagaagtt gatactaact gacctttaga ctgagcttta gctgcttggg tagcctcttg
    32641 agcagcttcg agcgaatcct cagttgactt gtctgcatga agaataaggg ctgctacaaa
    32701 gaaagaaaca actgctgcca ctaaaacacc tagaagaaca tttagatggg gccaaacacc
    32761 ttttggcgcc gtagccataa tcgcaataat agaacctggt gaagctggag atttaagacc
    32821 agcgtctaag agttgaaaag taaaagttcc agagatacct cctgccatag cagctaaaaa
    32881 tagagtaggc ttcatcataa cataaggaaa gtaaatttca tgaatccctc cgaagaaatg
    32941 aataaccatt gccccccaag aagaagattt agcagaacct ttaccgaata cagcataagc
    33001 taatagaatt cccaggcctg gtccaggatt agcttccaat aggaagagaa ttgacttacc
    33061 agcttgagct acctgttcta ctcccagagg agtaaaaatg ccatgattga gggcattatt
    33121 gaggaaaagg actttagccg gttcgatgat aatattagct ataggaagga ggcgagcatt
    33181 gacaatagcc tcaacaccat tcccaacagc tccagtaaga gtcgatacga ctggaccgat
    33241 tgcgtagaaa gccaaaagca ataatgcaaa accaacgaga ccagctgaga agttattaac
    33301 taacatttca aatccgggac gaattttttc ctggaacttc tcatcaaatt tcttgatagt
    33361 ccatcctccc agtgggccca ttaccatagc tccgataaac ataggaacac tagaacctgt
    33421 gattgcacca acagtagcaa tagctcctac aacggcacca cgttggccat ggatcatata
    33481 tccacctgtg taaccaatca ggattggcaa taaatacgtt aacataggac caacaacagt
    33541 agctaactgt tcatttggca gatagccatc agcgataaag agggcagtca atactcccca
    33601 agcaataaat gctccaatat tgggcataac catatttgaa agcgatgtcc ctagtttttg
    33661 aaccctgact ttcaatgata ctttttcttc cattagatca tcctcctttt cttaaaacta
    33721 gtatatacaa agttaaaaac ctttaaaact aaagttttgt cacaaatttt gtgtcaaaac
    33781 attacttttg acgaggctgg gcaaaaaggc ttaaaaatga taaaacgcat catatccggt
    33841 gtac
//
LOCUS       DAVKEV010000025        30843 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVKEV010000025 DAVKEV010000000
VERSION     DAVKEV010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30843
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.025"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(99..632)
                     /gene="queF"
                     /locus_tag="VWZ68_001216"
     CDS             complement(99..632)
                     /gene="queF"
                     /locus_tag="VWZ68_001216"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEU9372243.1"
                     /translation="MKRQSALVVFSGGQDSKTCLFWTMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(939..1253)
                     /gene="trxA"
                     /locus_tag="VWZ68_001217"
     CDS             complement(939..1253)
                     /gene="trxA"
                     /locus_tag="VWZ68_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU9372244.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(1270..1491)
                     /locus_tag="VWZ68_001218"
     CDS             complement(1270..1491)
                     /locus_tag="VWZ68_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU9372245.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(1590..1970)
                     /locus_tag="VWZ68_001219"
     CDS             complement(1590..1970)
                     /locus_tag="VWZ68_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9372246.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(2115..3068)
                     /locus_tag="VWZ68_001220"
     CDS             complement(2115..3068)
                     /locus_tag="VWZ68_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU9372247.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(3136..4344)
                     /gene="sstT"
                     /locus_tag="VWZ68_001221"
                     /pseudo
     CDS             complement(3136..4344)
                     /gene="sstT"
                     /locus_tag="VWZ68_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            4483..5043
                     /locus_tag="VWZ68_001222"
     CDS             4483..5043
                     /locus_tag="VWZ68_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEU9372248.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            5100..6008
                     /locus_tag="VWZ68_001223"
     CDS             5100..6008
                     /locus_tag="VWZ68_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU9372249.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            5960..6550
                     /locus_tag="VWZ68_001224"
     CDS             5960..6550
                     /locus_tag="VWZ68_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEU9372250.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            6553..7659
                     /gene="yqeH"
                     /locus_tag="VWZ68_001225"
     CDS             6553..7659
                     /gene="yqeH"
                     /locus_tag="VWZ68_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEU9372251.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            7873..8184
                     /gene="yhbY"
                     /locus_tag="VWZ68_001226"
     CDS             7873..8184
                     /gene="yhbY"
                     /locus_tag="VWZ68_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEU9372252.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            8236..8865
                     /locus_tag="VWZ68_001227"
     CDS             8236..8865
                     /locus_tag="VWZ68_001227"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEU9372253.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVEYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            8865..9458
                     /gene="yqeK"
                     /locus_tag="VWZ68_001228"
     CDS             8865..9458
                     /gene="yqeK"
                     /locus_tag="VWZ68_001228"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEU9372254.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVGKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            9459..9959
                     /locus_tag="VWZ68_001229"
     CDS             9459..9959
                     /locus_tag="VWZ68_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU9372255.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEEHFADVL
                     DYKHIF"
     gene            9972..10325
                     /gene="rsfS"
                     /locus_tag="VWZ68_001230"
     CDS             9972..10325
                     /gene="rsfS"
                     /locus_tag="VWZ68_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEU9372256.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            10428..11174
                     /locus_tag="VWZ68_001231"
     CDS             10428..11174
                     /locus_tag="VWZ68_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9372257.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            11184..12281
                     /locus_tag="VWZ68_001232"
     CDS             11184..12281
                     /locus_tag="VWZ68_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU9372258.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVNILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTARSVEELVELVTTKRY
                     TKARVRRLLTYILMQARENVLPEVIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGNPSIADQNFGRVPIRIETN"
     gene            12519..12773
                     /locus_tag="VWZ68_001233"
     CDS             12519..12773
                     /locus_tag="VWZ68_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEU9372259.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            12777..13031
                     /locus_tag="VWZ68_001234"
     CDS             12777..13031
                     /locus_tag="VWZ68_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEU9372260.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            13222..14835
                     /locus_tag="VWZ68_001235"
     CDS             13222..14835
                     /locus_tag="VWZ68_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEU9372261.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            14965..15591
                     /gene="gmk"
                     /locus_tag="VWZ68_001236"
     CDS             14965..15591
                     /gene="gmk"
                     /locus_tag="VWZ68_001236"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEU9372262.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            15616..15930
                     /locus_tag="VWZ68_001237"
     CDS             15616..15930
                     /locus_tag="VWZ68_001237"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEU9372263.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            15996..18392
                     /locus_tag="VWZ68_001238"
     CDS             15996..18392
                     /locus_tag="VWZ68_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEU9372264.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQVRILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTRNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            18405..19340
                     /locus_tag="VWZ68_001239"
     CDS             18405..19340
                     /locus_tag="VWZ68_001239"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEU9372265.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPNRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSICKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            19333..20646
                     /gene="rsmB"
                     /locus_tag="VWZ68_001240"
     CDS             19333..20646
                     /gene="rsmB"
                     /locus_tag="VWZ68_001240"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEU9372266.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVALKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFANGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            20661..21401
                     /locus_tag="VWZ68_001241"
     CDS             20661..21401
                     /locus_tag="VWZ68_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEU9372267.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            21398..23377
                     /gene="pknB"
                     /locus_tag="VWZ68_001242"
     CDS             21398..23377
                     /gene="pknB"
                     /locus_tag="VWZ68_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEU9372268.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            23492..24250
                     /locus_tag="VWZ68_001243"
     CDS             23492..24250
                     /locus_tag="VWZ68_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU9372269.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            24252..24701
                     /locus_tag="VWZ68_001244"
     CDS             24252..24701
                     /locus_tag="VWZ68_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU9372270.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            24763..25389
                     /locus_tag="VWZ68_001245"
                     /pseudo
     CDS             24763..25389
                     /locus_tag="VWZ68_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            25457..25705
                     /locus_tag="VWZ68_001246"
     CDS             25457..25705
                     /locus_tag="VWZ68_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372271.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            25836..27008
                     /locus_tag="VWZ68_001247"
     CDS             25836..27008
                     /locus_tag="VWZ68_001247"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEU9372272.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTVLSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            27008..28282
                     /locus_tag="VWZ68_001248"
     CDS             27008..28282
                     /locus_tag="VWZ68_001248"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEU9372273.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQDDPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(28318..29283)
                     /locus_tag="VWZ68_001249"
     CDS             complement(28318..29283)
                     /locus_tag="VWZ68_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9372274.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVTTTGYFLPVTLLPGKSI"
     gene            complement(29264..30718)
                     /locus_tag="VWZ68_001250"
     CDS             complement(29264..30718)
                     /locus_tag="VWZ68_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU9372275.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
BASE COUNT         9106 a         6098 c         7155 g         8484 t
ORIGIN      
        1 agctgacttc gtcagtttta tctacaacct caaacactgc tttgagtaac ctgcggctaa
       61 cttcctagtt tgctctttga ttttcattga gtatgacttt agcggttgtc aattttctct
      121 ggataaaggt cgtgttggaa gaggcgttgt tctgccaagc cctcatactt agttccttgc
      181 ttaccgtagt tatagtaggg gtcgattgaa atgccaccgc gcggagtgaa ttttccccag
      241 acttctaaat agcgagggtc tagcaagttg accaagtctt tcccgatggt gttgatacag
      301 ttttcgtgga aatctccgtg gtttcggtag ctaaatagat atagtttgag ggattttgac
      361 tcgacacaga gcttgtcagg aatgtaggaa atatgaatcg tcgcaaagtc tggctgagca
      421 gtgatttgtc ccagcagaga catatcgagg atatggtgac gaatgccctg ttccttagcg
      481 atttctctag taatttgaat ttcgaggtga tgacgttggc cgtaggcaaa ggtgacagct
      541 tcgactgttt catagtgttg catggtccag aaaaggcagg tttttgaatc ttgaccacca
      601 ctaaagacga ccaaggctga ttgacgtttc atagtactcc ttccaaaatg ggaaatgttc
      661 agagcacgta aaaagctccc attagggagc taaaaaatac caaatcgagg ttttttttag
      721 cgatggcata tcccaaatat cgtaatattc tatttatata gtaaaatgaa ataagaacag
      781 gacaaatcga tcaggacagt caaatcgatt tctaacaatg ttttagaagt agagatgtac
      841 tattctagtt tcaatctact atagtctagc atatcttttg aaaaatggca aagggcaaga
      901 aaaaagagac caaagaaagt acttggtctc tcgtttgatt agctcaattc agcaatgatg
      961 gccttgattt gttctgctgt gtgaacacct gcaacttgtt tgacaacttg gccgtctttt
     1021 ttgaagagaa gagttggaat agacatgatt ccaaaagcac gagctgtgtt tggattttca
     1081 tcaacgtcca ttttaacgat tttcaagaca tcttctgaaa gttcttcaga caatttgtcc
     1141 aagattggac cttgcatacg acatggacca caccaagttg cccagaagtc tactaagacc
     1201 aaaccgtctt ttgtttcttg ttcgaatgtt gcatctgtaa ttgcttttgc cattgtattt
     1261 ctcctttttt tagttatatt ggcttaaatc ttgtttcatg agatagaaga agatatctcc
     1321 ataagtccca tggtagtcca aattatgacc cttgtaagtt aatttttgga cagggtagta
     1381 gtctgcgacg ccgataaggc aagcttgttg cgaacgttca aagtcttcat aagactcgaa
     1441 agtcacagtt ctttcgttct tgctggcatc tatataggta atttcaatca tgtttaaaac
     1501 tcctttgttt aatgctaact ttattttact ccttataaaa gagaatgtca agaaaaatga
     1561 ttgcgcacgc aacttttttt aaaatcatct taaatcaaga aatccaaacc tgcttccaag
     1621 ctttcttcga cagtcttttg tagcgaggcc agtgtctttt gcccatcatt tgtcaggcag
     1681 ataaaactag agcgtctatc ttgatggcaa cacatgcgac tgagtagacc gcaattttta
     1741 gcttccaagc gagccaccat cctagaaact gcgctcgggc tcagatgaag cttatctggc
     1801 aggtcaatct ggcgtagaga tttttcttca gccaagtcca gatagtagag caggtagaac
     1861 tctttcaagg tcagactttg ctcgctctgt tgggcaatgg tctcttccaa gagactttca
     1921 atttctttct gacgccgatt gaagtcaaac catttttcca aataggtcat agtgtctcct
     1981 ttctttttag agtcataatt atagaagaaa gtccattaac gggcagtctt tgcgtcataa
     2041 gatgattgcg catgcaataa ttatactact tttcaagaat gctggcaagc tctgtttttt
     2101 agtggttttc ttttttactg tctatatttt tggtaaaaat caacttttac ttggatgaag
     2161 gttttggctt cacgtaggag ttgaagaaga gtggcgcggg tttcaaactc ttctcttgtc
     2221 ttgggcagac tgcggttccg gaagacttcc agataacgtt caatttcatc tagcaaatca
     2281 gaagcaggat tggtctggct cagttgacct gcaatttttg aaaagagttg cgctaagatc
     2341 aggctttcac tggcggcaag gtgacaagtg ttaatctgtt gggccatgtt tctcaggata
     2401 cgactttgtc gttgtctcat ctcaaagtag tggatatggt agtcggtctg gtgaaagagg
     2461 tggtcagagt gatccaaata gaccagtctg agggcttctt tcaaaagcgt gtctaattct
     2521 gctaccagct gtgctcggtt gcgtccgtct cctctggata aatagtattt gaagcgctgg
     2581 aggatatctt ttaacttttc ttccaccagc gtgtggtagt gctggatttc ctcttctcgt
     2641 gaaggcatat agagattaac aagcaaggca aatcctgtac caatagcaaa gagaaggaat
     2701 tcgttgacta ggaggtctgg agaggttgac tcttgaacca agagatggct aaccaaaacc
     2761 gtgcttggtg tgatgccaat ttcccagccc atcttgtagg ctaaaggaac gtagaaggcc
     2821 agatagaggc cgagactcca gatatgaaat ccgctcaagt gaaaagctag aacgccgata
     2881 gccagagcta gaagcataga aaaaagacga ttgcgagcca gttttaaagt acttctacgc
     2941 gtatcagata ggctcaagag agcgataatt ccagccgaaa ctgctgacga aagattgaga
     3001 aaataagcaa gcaggcaggc aagacaggta gctaagatga gcttggtcgt acgttggcta
     3061 atagacataa gaatttccta ataagttaga ataaaagcgt aaaagacaag acatgagcag
     3121 gcttgccttg atgagttatt ttttacgggt tgctgcgtat tcggcaacgg cggtaaagag
     3181 gacatctgta gaagagttaa gggctgtttc acatgagtct tggatgacac caatcacaaa
     3241 accaacccca acaatttgta tggcaatatc gttagaaata ccgaaaaggc tacaagcaac
     3301 tgggataaga aggagggaac ctccggcaat acctgaagca tcacaggctg agatagctgc
     3361 taccacactg aggacaaagg ctgtggcaaa gtcaacagga attccaagag tgttaactgt
     3421 aacaagggtc aaaacgttaa tggtaatcgc tactccagcc atattgatag tagaaccgag
     3481 tgggatagaa acagaatagg tatctgggtt gagtccaagg tcatggcaga gtttcatgtt
     3541 gacaggaatg ttagtcgcag aactacgagt gaaaaaggct gtcacaccgc tgacacggag
     3601 gcagttccaa actagagggt aaggattgcg tctcataaag aagaaggcaa tcaaagggtt
     3661 gaccacaggg gcaacaaaaa gcatagtcgt tactaataga accaataaaa taccgtagtt
     3721 ggcaaggctt ccgactccct tgtcagaaat ggttttaaaa acaagaccaa ggattccaaa
     3781 tggagccaga ttgatgatcc attcgacaat tttagaagtc acgtcagcga tagtttttag
     3841 caattcttta ctatttttac tggcttctct catagcgatt ccaaaaatga ctgcccaaga
     3901 taagattcta atatagttag cagtaagcag ggcgttgact gggttgtcaa ccagtttgag
     3961 caagaggttg ctgaggacct gcccaatccc atctggtggt gcaatttcag tattggcact
     4021 atttagggta atttcaatag ggacgatgaa acttgctagt acagctacaa gagcagcggc
     4081 gaaagtccct atcataggat atacaagaaa acaacagttt tcatattgct atcttgtccc
     4141 ttttgatgtt ggaaagggca ttggcaacga gggcaaagac taggatagga gcaacagctt
     4201 ttagacctcc aacgaataaa tccccgagta gcccaatccc tgagagatta ggaagggtca
     4261 gtcctaggat tccccacaaa gcataccaat caagatacgc ttgacaaggc ttgccttatt
     4321 ccaagcatga atgattcttt tcataataat ctcctttttg tgtagtgatt atgattatag
     4381 tataaatgat agacaaaatc aagaattttc tgtctatttt ttgaatattt atggagaatg
     4441 agactgatga aaatatggta taatgaaata aaggagtttt atatgcaaaa atttattcag
     4501 gcttatattg aaaagctaga tgtgacaacc attatcgaga atattctaac caaggtcatt
     4561 tctcttttac tgcttttgat tgtattttat attgctaaaa aaatgcttca taccatggtg
     4621 cagagaattg tcaaaccttc tctaaaaatg tctcgtcatg atgtcggacg ccaaaaaacc
     4681 atctcacgtt tactagaaaa tgtgtttaat tatacgctat atttcttttt actctactgc
     4741 attttgtcga ttttaggttt gccagtttct agtttgctgg ctggagctgg tattgctggg
     4801 gtagcgattg gtatgggagc ccaaggcttt ctgtctgatg tcatcaatgg ctttttcatc
     4861 ctctttgaac gtcaactgga tgtgggagat gaggtcgttc tgacaaatgg accgattact
     4921 gtatcgggta aggttgtcag tgtgggaatt cgtacgacac agcttcgtag cgaggagcaa
     4981 gcccttcact ttgtccctaa ccgaaatatc acagttgtta gcaatttctc acgcacagac
     5041 tagacctgtt attttaagta atttgtggta caatagaggg agtttaataa ggagaaaaga
     5101 tggttttaga aaagcagttg ggcaatggtt gtacctggat agacctagac ctaggaaagt
     5161 tgaataaact agaagacctt tctgaaattt acggtttgga caaggaaacc attgaatacg
     5221 cactggatag aaacgagcgc gcccacatgg attaccaccg tgaaagtggg acggttacct
     5281 ttatctataa tgtcctagac gtaaaaaagg acaaggccta ctatgagact tttcccatga
     5341 cctttattgt cgagcatcgt cgcctgatta ccattagtaa taccaagaac gcctatgtca
     5401 ttgaacagat gactcgttat ctggagagcc atgacacgct ttcgatttat aagtttctct
     5461 ttgccagtct ggaaattatc agcaatgcct actatcctgt cattgagcag atggacaaga
     5521 gtagggatga ggtcaatgac ctcttgcgcc agcgaactac caagaaaaac ctctttgccc
     5581 tgtctgattt ggagactggt atggtttatc tgacggcagc tgccaaacaa aatcggattt
     5641 tgttagagca tattcaaggt catgccttgt atcgtagttt tgatgagatt gagagagaac
     5701 agtttgatga tgccatgatt gaggctcatc agctggtatc catgacagac ctaatctctc
     5761 agattttaca gcagctttca gcctcttaca acaatattct aaacaataat ctgaatgaca
     5821 atttgacaac cttgactatc atttcagtct tgctagctgt tttggcagtc gtgacaggct
     5881 ttttcggaat gaatgttccc ttacctttaa cagatgagcc ccatgcttgg ctctatatca
     5941 gtttggctag tgcaggtttg tggattgttt tatccttgtt actaaggaaa attgcgaaaa
     6001 aaagttaaga aaaggagcca gaatggcgat tgaaaattat ataccagatt ttgctgtgga
     6061 agcagtctat gatctgacag tcccaagcct gcaggcgcag ggaatcaagg ctgttttggt
     6121 cgatttggat aataccctca ttgcttggaa caaccctgat ggaacgccag agatgaagca
     6181 atggctacat gaccttcggg acgcgggtat tggcattatc gtagtgtcaa ataacaccaa
     6241 aaaacgcgtt caacgagcag ttgagaaatt tgggattgat tacgtttact gggccttgaa
     6301 gcccttcaca tttggtattg accgtgctat gaaggaattc cactatgaca aaaaggaagt
     6361 ggtcatggtt ggcgaccagc tcatgacaga tatacgagca gcccaccgtg cagggattcg
     6421 gtcaatttta gtcaaaccct tggtccaaca tgactcaatc aaaacgcaga ttaaccgaac
     6481 tcgtgagcgt cgtgttatga gaaaaatcac tgaaaagtac ggaccgatta catataaaaa
     6541 aggaatttaa ctatggaaga aattctctgt attggttgtg gagcaaccat tcagacgaca
     6601 gataaagctg gtcttggttt taccccccag tcggcacttg aaaaaggttt ggagactggc
     6661 gaagtctatt gccaacgctg tttccgtctc cgccactaca atgaaatcac agatgtccag
     6721 ttgacgaacg atgatttcct caagctcttg cacgaggtgg gagacagtga tgccttagtg
     6781 gtcaatgtca ttgatatctt tgattttaat ggatctgtca tcccaggttt accacgtttc
     6841 gtctcgggca atgatgtcct cttggtagga aataaaaaag atatccttcc taagtcagtt
     6901 aagtctggta agattagcca gtggctcatg aaacgtgccc atgaagaagg tcttcgtcca
     6961 gtcgatgtgg tcctaacttc agcacaaaat aaacatgcca ttaaggaagt cattgacaag
     7021 attgaacact accgtaaggg ccgcgatgtc tatgtggtcg gtgtgaccaa cgttggaaaa
     7081 tcaactctaa tcaatgctat tatccaagaa atcacgggtg atcagaatgt catcactact
     7141 tcacgcttcc caggtacaac cttggacaaa atagagattc cgcttgacga cggatcttat
     7201 atttacgata cgccgggaat tatccaccgc caccagatgg ctcactactt gacggccaaa
     7261 aacctcaagt atgtcagtcc taaaaaggaa atcaagccta agacctatca gcttaatcct
     7321 gagcaaaccc tatttttagg tggtttggga cgctttgact ttatagcagg agaaaagcaa
     7381 ggatttactg ctttctttga taatgaactc aaactccatc gtagcaagct tgaaggagct
     7441 agtgctttct acgataagca cctgggaact cttctgacac caccaaatag caaggaaaaa
     7501 gaagatttcc caaggctagt ccagcatgtc tttaccatta aagataagac agacctagtc
     7561 atctcaggcc taggctggat tcgtgtaaca ggcatagcaa aagtcgccgt ctgggcacca
     7621 gaaggcgtcg ccgtcgtcac acgaaaagca attatttaaa acaaaatcgc tgagcgaaca
     7681 aagtgagctc atatagcgat agttattgcc gtggtgtgat tgccaatctg tagattggca
     7741 aggggcacaa ttgagaccaa ggctcaattg tgaggtcagg aaatccattt ttcaaagatg
     7801 aaatctttgg aaaattagtt ccgaccgtcc ctcaccacct aaaataacta tccaaaaaca
     7861 aggaagaaaa ttatgtcatt aacatcaaaa caacgtgcct tcctcaacag ccaggcacac
     7921 accctcaaac ctatcatcca aatcgggaaa aatggactca acgaccaaat caaaaccagc
     7981 gtccgtcaag ctcttgatgc gcgtgaatta atcaaggtta ctctcttaca aaacacagat
     8041 gaaaacatcc acgaagtagc tgaaattttg gaagaagaaa tcggtgtgga tacagtccaa
     8101 aaaataggac gcatcttgat tttgtttaaa caatctagca agaaagaaaa tcgcaagatt
     8161 tctaagaaag tcaaagaaat ctaagaccga aactccaaat aactgttttt atagagaaat
     8221 aaaggggact agcctatgac aatcgaacta ttgactccct ttaccaaggt agagttggag
     8281 ccagaaatca aggagaaaaa acgcaaacaa gttgggattt taggggggaa ttttaaccct
     8341 gttcacaatg cccatctcat tgttgcggat caagtacggc aacagttggg actggatcaa
     8401 gttcttctca tgcctgaata ccaacctcct cacgttgata aaaaggaaac catccctgaa
     8461 caccatcgtc tcaagatgct tgagttggca attgagggaa ttgacggcct agtcattgaa
     8521 accattgagt tggagcgcaa gggtatttcc tacacctacg acaccatgaa gattttgaca
     8581 gagaagaatc cagatacgga ttattacttt atcatcggtg ccgacatggt tgagtatctg
     8641 cctaagtggt accgaattga tgaactggtt gacatggttc agtttgtggg ggttcagcgt
     8701 ccacgctaca aggtagggac ttcctatcca gttatctggg tggacgtacc gctcatggat
     8761 atctcgtcca gcatggtgcg ggacttcctt gcccaaggtc ggaaacccaa ctttctccta
     8821 cctcagccag tgctagacta catcgagaag gaggggctct actgatgtcc tatcaagact
     8881 atatcaactg ctcccgtgag gccttgttgg aaaaaatggc agagcttcta cctgagaaac
     8941 gtctaaccca ttgtctaggt gtggagcgtg ccgctatgga attagctcag cgctttggtg
     9001 tagatgttgg gaaagcaagt ctagcaggtc ttcttcatga ctatgctaaa aagttgtcaa
     9061 atcaggaatt tctagccttg attgaccgtt accagctaga ccctgacctc aaaaactggg
     9121 gcaataatgt ctggcatggt atggtcggaa tttacaaaat tcaggaagat ttggatttgc
     9181 atgattctga aattctgcga gccattgaaa ttcatacagt cggagctggt caaatgacag
     9241 acctagataa ggtcatctac gtcgcagact atatcgagca caatcgagcc tttcctggag
     9301 tagatgtggc gcgtgagatt gcaagtctat cgctcaataa ggcggtggcc tacgaaacag
     9361 ctcgtaccgt ggagtatcta gctcatcagg gattccccat ctatccccaa acccttgaaa
     9421 cctataacgc ctttgtgcac tatttgaaag aggactaaat gaagacggct tttataatca
     9481 ttgatgttca gaatgtttta gtagaaactg ggttccagac aaaaagtcta ttggaaaaaa
     9541 tttcttattt acaaaaccag gctagaagca agaatattga aattatctat gttcaacata
     9601 ttgagaattc tgaagctcaa acatcagaag attggcagtt atctgcgctt ttaaatcgaa
     9661 aacctgctga aaaggtcttt cagaagaagt ataacagtat tttcaaagaa actggcttaa
     9721 aagaatactt ggataaacag gggattgaaa aattagtttt atgtggtatg cagacagaat
     9781 attgtgtgga tacctctgtc aaggttgcct ttgaatatgg ctatcagctt attgttccag
     9841 aaggtgctgt cacaaccttt gatggggatg acattccagc agaaacgatt aatgaatttt
     9901 atgaggacat ttgggaggag cactttgcag atgtcctaga ttacaaacat attttctaaa
     9961 aagaggatta aatgaacgaa aaagaattac tagaactagt cgtgaaagcg gctgatgaga
    10021 aacgtgcgga ggatatcctc gcacttgatg tacaagattt gactagtgtg acggactact
    10081 ttgtcatcac tagctcaatg aatagccgtc agttggacgc tatcgcagct aatatccgtg
    10141 aaaaagtagc tcaagcgggc tttaaaggta gccatgtcga aggcgatgca gctggaggct
    10201 gggtcttact ggacctcggt gctgttgtcg tgcatatctt ttcagaagaa atgcgtgccc
    10261 attataatct agagaagcta tggcatgagg cgaattcagt agatatttca gaagctcttg
    10321 cttagaagat gaactcagtt gtagtcaact gggtttcttt gcttatttta gaaaaattga
    10381 tagaaaggta aagggctagt ggtgtttacc atggagctct tagtatcatg attatggcga
    10441 cttatgaaac ctttgcggcg gtctatgatg cggtcatgga cgatagttta tacgacaaat
    10501 ggacgaattt ttctctgcgt catttgccta agaccaagga gaaaaagaaa ctcttggaac
    10561 tggcttgtgg gacaggaatt caatcagtgc gcttctctca ggctggtttt gatgtgactg
    10621 gacttgactt gagtgcggat atgttgaaga ttgcggagaa gagagcaact tcagccaagc
    10681 aaaagattgc ttttatagaa ggtaacatgc tgaatttgtc caaggcaggg aaatacgatt
    10741 ttgtcacgtg ttattcggac tctatctgct atatgcagga tgaggtggaa gtaggggacg
    10801 tctttaagga cgtgtacaat gcgctgaatg aagagggagt tttcatcttt gacgtgcact
    10861 cgacctacca gacagatgaa gtattccctg gctattccta ccatgaaaat gcggaagatt
    10921 ttgccatgct ttgggataca tatgaggacg aagctcctca ctccatcgtg catgagctga
    10981 ctttctttat caaggaggct gacggttcct ttagtcgcca cgatgaagta catgaggaga
    11041 ggacctatga gatcttgacc tatgatatct tactggaaca ggctggattc aagtccttca
    11101 aactctatgc agactttgag gataaggaac caacagaaac tagcacccgt tggttttttg
    11161 tggcgcagaa gtaggagatt agcatgacca tcacaggtat tatcgcggag ttcaatcctt
    11221 ttcataatgg ccataaatac ctgctggatc aggcagaggg actgaaaatt gttgccatgt
    11281 cagggaattt catgcagcgt ggagagcctg ctattgtgga taagtggaca agggcccaga
    11341 tggcgctgga aaatggcgca gacttggtag tggaattgcc ctttttagtc agtgttcagg
    11401 cagctgattt ctttggtcaa ggagctgtga atatcttgga tcgcttgggc attgatagtc
    11461 tagtttttgg gacagaggaa gttcgagatt atcagaaaat cgctgactta tacacagaga
    11521 aaggtgctga gatggagaaa tttgtggaaa atctgcctga ttccctttcc tatccccaga
    11581 aaacccaagc tatgtggaag gaatttgctg gtcttgattt ttcaggtaat acccccaatc
    11641 atgttcttgc tctggcctat gccaaggcgg ttgcaggacg aaatatcaag ctgcatccga
    11701 ttcagcgtca gggggcaggt taccattctg tgaataaaga tgtggacttt gcctcggcga
    11761 cagccctccg tcaacatcag aaggaccaag atttcttaga acgctttatg ccttctgttg
    11821 ccctatttga gcaggccagt aaggtgatct gggaagacta ttttcccttg ctccgctatc
    11881 aaatcttgtc aaatcccgac ctaaccacca tctatcaggt caatcaagaa atggctgtgc
    11941 gcattaaaga agctattaaa acagcccggt ctgtggaaga attggtcgag ttagtgacta
    12001 ccaaacgtta caccaaggcg cgtgtcagac gcctattgac ctatattttg atgcaggcta
    12061 gagaaaatgt cttgccagaa gtcattcatg tccttggatt tactgaaaaa ggtaggcaac
    12121 atctcaagtc tttgaaaggt caggtcagtc tagtcagccg aattggcaaa gaaccttggg
    12181 atgctatgac ccaaaaagca gaccagattt accaactagg aaatccaagt atagcagacc
    12241 agaattttgg aagagtgccg attagaatag aaacaaacta agtctaccga aaggtaggct
    12301 ttttgagatt ttttacgaat aatactcttc gaaaatcaaa ttcaaatcgc gtcaacgtcg
    12361 ccttgccgta ctcaagtaca gcctgcggct agtttcctag tttgctcttt gattttcatt
    12421 gagtataaat agatagaaaa gaaaatcttg tacaagttcc tgacaatttc tttcttttcg
    12481 tgtataatag tggaaaagag ctaaaacgag gtatggttat ggaagcagtc ctttactcaa
    12541 cattccgaaa tcatttaaag gactacatga agaaggtaaa tgatgaattt gagcctttga
    12601 cggtggtcaa taaaaatcca gatgaggaca ttgtagtcct ttcaaagagt gagtgggata
    12661 gtatccaaga aaccctgaga attgctcaaa ataaggaact ttctgataag gttttgcgag
    12721 gaatggctca agttcgtgct ggaagtactc aggtccatgt tattgaggag taagaaatgc
    12781 tgctcaagtt tacagaagat gcctgggcag attattgcta ctggcaaaat caggataaga
    12841 aaacgttaaa aagaatcaat aaactaatca aggatattca acgtgatccc tttacaggaa
    12901 taggtaaacc agaaccactc aaatatgatt accaaggagc ctggtcacgg cgtattgatg
    12961 cagaaaatcg cttgatttat atgatggatg gagatagcgt ggctttcttg tcctttaaag
    13021 atcattacta agtctattga aaggtaggct ttttctcaag tctctactaa actactattt
    13081 ctaaacaaca agtttatttt tgcaaatgtg ttccaaattc cccaaaacat attctatttt
    13141 aggtttgtga aaatcacttt tttatggtag aatgtaaaag aatgtatgtc attcggaata
    13201 acaataaaat gaggtaaaaa catggaaatc atgtcgcttg cgattgctgt ttttgccgtc
    13261 atcattggtt tagtcattgg atatgtcagc atctcagcta agatgaaatc atctcaggaa
    13321 gctgcagagt tgatgctttt aaatgctgaa caagaagcaa ctaatttacg tggacaagct
    13381 gagcgtgaag cggatttact tgttaatgaa gccaaacgtg aaagcaagtc tcttaaaaaa
    13441 gaagcactat tggaggccaa agaagaagcc agaaaatacc gtgaagaagt ggacgctgaa
    13501 ttcaaatcag aacgtcaaga actcaaacaa atcgaaagtc gtttgacaga gagagctact
    13561 agccttgacc gtaaggacga caatttgacg agtaaagaac aaacacttga acaaaaagaa
    13621 caaagtattt ctgatagagc gaaaaacctt gatgcgcgtg aagagcaatt agaggaagtc
    13681 gaaagacaaa aagaagcaga actagagcgt attggtgctc tgtctcaggc agaagcacga
    13741 gatattatct tggctcagac agaggaaaac ttgaccaggg agattgccag tcgcattcgc
    13801 gaagctgagc aagaggtcaa ggaacgttct gacaaaatgg ccaaggacat cttggttcaa
    13861 gctatgcaac gtatcgctgg tgaatatgta gcggagtcaa caaactcaac ggttcatctg
    13921 ccagacgata ctatgaaggg acgcattatt ggtcgtgaag gtcgtaacat tcgtaccttt
    13981 gaaagtttga caggggtcga tgtgattatc gacgatacac cagaagtggt gaccttgtca
    14041 ggatttgatc cgattcgtcg tgagattgcc cgtatgacta tggaaatgtt gctcaaagat
    14101 ggtcgtatac atccagctcg tatcgaagag ttggttgaga aaaaccgtca agagattgac
    14161 aataagattc gtgaatacgg tgaggctgct gcctatgaaa ttggtgcgcc aaaccttcat
    14221 ccagacttga tgaagattat gggacgtttg cagttccgta cttcatatgg acaaaatgtt
    14281 ttgcgccatt cgattgaggt tgctaagttg gctggtatca tggcgagcga acttggtgaa
    14341 aatgcggctc ttgcccgtcg tgctggattc cttcacgata tcgggaaagc cattgaccat
    14401 gaggttgaag gtagccacgt tgaaatcggt atggaattgg cccgtaagta caaggaaccc
    14461 ccagttgtgg tgaatacgat tgctagtcac cacggagatg ttgaagctga gagcgtgata
    14521 gcagttatcg tcgctgcagc agatgccttg agcgcagccc gtccaggtgc tcgtagtgag
    14581 tctcttgaaa gctacatcaa gcgtctccat gatttggaag aaattgctaa cggctttgaa
    14641 ggagtgcaaa ctagctttgc ccttcaagca ggacgtgaaa ttcgtatcat ggtcaatcca
    14701 ggaaaaatca aggacgacaa agtcacaatc ttggctcaca aagttcgtaa gaaaattgaa
    14761 aacaatctcg attatccagg aaatatcaag gtaaccgtga ttcgcgagct tcgtgcagta
    14821 gattatgcta aataaataag aaagagcagt tgaaaaatta ctgctttttt gttacactag
    14881 atagaaagac tgtaaaggat aatctggctt tttgccatta ttctagagaa atgttatttc
    14941 acagattgac taaaaggaga cacaatggca gaccgaggct tactaatcgt tttttctggt
    15001 ccttcagggg ttggaaaagg aacggttaga agagagattt ttgagagttc tgaaaaccaa
    15061 tttcaatact ctgtatcgat gacgacacgc gcacaacgtc ctggagaagt ggacggtgtc
    15121 gactatttct tccgtactcg tgaagaattt gaagagctga ttcgtcaagg acagatgttg
    15181 gaatacgcag aatatgtcgg taactactat ggaactcctc tgacctatgt caatgaaacc
    15241 ttggacaagg gaatcgatgt tttccttgaa attgaagttc agggtgctct tcaggtcaag
    15301 aaaaaggttc cagatgctgt ctttatcttc ctgacaccac cagatttgga tgaattgcaa
    15361 gatcgcttgg taggtcgtgg aacagatagt gcagaagtga ttgcccaacg aatcgaaaag
    15421 gccaaggaag aaattgccct catgcgtgag tatgattatg ccattgtcaa cgatcaggtg
    15481 cccctagctg ctgaacgtgt caaatgtgta attgaagcag aacacttctg tgtggatcgt
    15541 gtcattggtc actatcagga gatgttacca aaatctccaa ctacccgata aaatttagaa
    15601 aataggtaca agcaaatgat gttaaaaccc tctattgata ccttgctcga caaggttcct
    15661 tcaaaatatt cactcgtaat cttggaagca aaacgtgccc acgaattgga agcaggtgcc
    15721 ccagcaactc aaggtttcaa gtctgaaaaa tcaactcttc gcgctttaga agaaatcgaa
    15781 tcaggaaacg ttacaattca cccagatcca gaaggaaaac gcgaagcagt gcgtcgccgt
    15841 atcgaagaag aaaaacgccg caaagaagaa gaagaaaaga aaatcaaaga gcaaattgct
    15901 aaagaaaaag aagatggtga aaaaatttaa ggttgggggg actcaatctt attttttcta
    15961 ttgcaagaat gtactgacaa ggaggaggtg agaagatggc cctagctaag attatcgtag
    16021 atgtgccctt gatgcagacg gaccagccct atagttacag gattccggag gaatttgagg
    16081 gaatgctgga agttgggatg cgggttcatg tgccttttgg taagggtaat cgcctgattc
    16141 aagggattgt tcttggtttg gagtcccaat cagatggaga agagatggag caagatttaa
    16201 aagatattgc agaggtgctg gatttttctc ctgttctcac gccagaacaa ctctggctgg
    16261 ctgaggagtt acgcaaatct gtcttctcct acaaaatttc tatcctcaag gccatgcttc
    16321 caggatttct gaattctagc tatgacaaga ttctctatcc tctggaaggc ttgagtcagg
    16381 aagaacgagt gcgcctgttt ggttcagaag attcgctagc cttttcttca ctagaccttg
    16441 ccaagcaagc tgaaatgatg cgtttgacta gaaaaggcct gcttggtctg gaatatcagg
    16501 cagtcgatca aaagaaggtc aagacccagt cttggtatga ggttgaccat gctcaattag
    16561 aaggtgttga gatttctaca cgtgccaaga aaaagttgga actgagagat tatctgctgt
    16621 ctcatccaga gagcgcttcc ttggctagct tgttagagtc ctactcgcga gagcaagtca
    16681 acttctttgt ggatcaaggt gctgttacca tagtccaaaa ggaagttcaa cgctcggctg
    16741 cttattttga aggaattgaa gcaagtagac ctttggagtt aaatccagaa caaagacagg
    16801 cgcgtgatgc ggttgtgagt tctattggca gttctcaacc tccctttcta cttcaaggga
    16861 ttacaggaag tgggaagacc gaggtttact tgcagattat ccaaggtgcc ctggataagg
    16921 gcaagacagc tattttgctg gtacctgaga tttccttgac tcctcagatg accgagcgtt
    16981 ttatagcacg ttttggggac aaggtagcca ttcttcactc aggattatcc aatggtgaaa
    17041 agtatgatga atggcgcaag gtggagcgtg gcgatgccca agttgttgtt ggtgccagat
    17101 ctgctatctt tgctcctctg aaaaatctgg gtgtcatgat tattgatgaa gagcatgaag
    17161 cggcttataa gcaggacagc aatccccgtt accatgccag agaggtagct attttacggg
    17221 ctcagtataa tcaagcaact ctggtacttg gatctgcaac gccgagctta gagagccggg
    17281 cacgtgctgg caaaggcgtc tatcaacact tacgtctaac ccaacgtgcc aatcctttgg
    17341 ctacaatccc tgaggttcaa gtgattgact ttcgagacta tatcggacaa aatgagacgt
    17401 caaactttac gcctcctttg ctagaggcta tccaagaccg tctggttaaa aaagagcagg
    17461 tggttctcat gctcaatcgc cgtggttatt ctagctttgt catgtgtcgg gagtgtggga
    17521 cggtggatac ttgtcccaac tgcgatattt ctctgacctt gcatatggat accaagacta
    17581 tgaactgcca ttattgtggt ttctcgaagg atattcctca ggtctgtcct aactgtaaga
    17641 gccacagtat tcgttactat gggacgggaa ctcagaaggc ttatgatgag ctagcagaac
    17701 tctttcccca agttcgcatt ttgaggatgg atgtggatac gactcgaaag aaaggcagtc
    17761 accaagcctt gcttgaccag tttgggcgag gggaagcgga tattttactt ggtactcaga
    17821 tgattgcaaa gggtttggat tttcccaatg ttaccctagt aggagttcta aatgcggata
    17881 cggccttgaa tctgcctgat ttccgttctt ctgagagaac cttccagctc ttgactcagg
    17941 tggcaggtcg agcaggtcgg gctgaaaaag caggtcaagt cttgatacag tcctacaatt
    18001 cgcagcacta tgctattcga tttgccaagg atcaagatta cgaaggcttt tatgcctatg
    18061 aaatgggaat cagacgacaa ctcggctatc caccttacta tttcacgatt ggtattaccc
    18121 tttctcacaa gaaagaagaa gaggttttca aacgtgccta tgaagtcatg aacattttgc
    18181 ggtcaggctt gtcagagacc agtcccattc tggggccaac gccaaaaccg attgcccgta
    18241 cccgcaacct ctatcattac cagattttaa ttaaataccg tttagaagat gagctggggc
    18301 cgaccctcaa ccaggtcttg gccttgactc aagaacggga aaatagtgag ctccgtctca
    18361 gcattgacca tgagccgcag caatttttat aagaaggaga agatatgaca aaactaatct
    18421 ttatggggac ccccgacttt tcagcaacag tcttaaaagg acttttgaca gatgaccgtt
    18481 acgaaattct agccgttgtg acccagccaa accgtgctgt tggtcgtaaa aaagttatcc
    18541 aagaaacccc agtcaagcag gctgccaagg aagcaggact atctatctac caacctgaaa
    18601 aattatctgg aagtccagag atggaagatc ttatgaagct aggagcagat ggaattgtga
    18661 ctgctgcttt tgggcagttt ctcccaagca aactccttga tagcatggac tttgctgtca
    18721 acgttcatgc ctccctcctt cctagacacc gtggtggtgc gcctatccat tatgccttga
    18781 ttcaagggga tgaggaagct ggtgtgacca tcatggaaat ggttaaggaa atggatgcag
    18841 gagatatgat ttctcgtcgc agcattccga tcacagatga ggacaatgtt ggcaccttgt
    18901 ttgaaaaatt ggcgctagtt ggtcgtgatt tgcttttgga cactctgcct gcctatattg
    18961 ctggtgatat caaacctgaa ccgcaggata cgagtcaggt taccttctct ccaaatataa
    19021 agccagagga agaaaaactg gactggaaca aaaccaatcg tcaactcttt aaccaaattc
    19081 gtggaatgaa cccctggcct gttgcccata ctttccttaa gggcgaccgc tttaagattt
    19141 atgaagccct accagtagaa ggtcagggaa atccaggtga gattctctct atctgcaaga
    19201 aagaattgat tgtcgcaacg gctgaagggg ctctatccct caaacaagtg cagccagctg
    19261 gtaagcctaa gatggacatt gcttccttcc tcaacggagt tggacgtaca ttgactgtag
    19321 gagaacgatt tggtgactaa agtagaaacg gctagaagtt tagctctagc agtgctagag
    19381 gatgtttttg tgaatcaagc atattcaaat attgccttaa ataaacacct caaggggagt
    19441 cagctctctg cagcagacaa gggcttagtg accgagctag tctatggaac ggtagccctt
    19501 aaactgactc tggaatggta cctatcccac tttatcgaag acagagacca gttagacagc
    19561 tggctctatg tccttcttct catgagtgcc taccaactcc gctatttgga caagattcca
    19621 gatcatgctg tggtcaatga agcagtggaa ttggccaaac tccgtaaaaa aggcagtgaa
    19681 aaattggtca acgctgtcct tcgccgtatc ttgcgtgaag gctggccaga tattgctagc
    19741 atcaagcgaa aaaacaagcg tgactccatt gcctattctc tcccagtttg gctagttgcc
    19801 aaactcaagg aagaatacgg agaggagaga gcaaaagcca tctttgaaag cctgttagtg
    19861 cgaaacaaag ccagtattcg tgtaacagac ctaagtcgaa aagaggaaat ccaagccttg
    19921 ttggaggcga ataattccct tttagcaacc actggtctgg ttaaggagca ggggcatttt
    19981 gcagggcata atttgtttgc gaatggagcc attaccatcc aagatgagtc cagtcagctg
    20041 gttgctccga cgcttgattt acaaggtgat gagcgagtgc ttgatgcctg tgcggctcca
    20101 ggtgggaaaa cagcccatat agcctcttat cttacgacag gtcaggttac tgctctggac
    20161 ttgtacgacc acaagttgga tttaattcaa gaaaatgccc aacgtctggg agttgcagat
    20221 cgggttcaaa ctcaaaaatt ggatgccaga aaggtgcatg agttttttga ccaggattcc
    20281 tttgataaga ttttggtgga tgctccttgt tcaggaatcg gtcttttgcg ccgaaaacca
    20341 gatatcaaat acaataaaga aacggcagat ttcgcgtcct tgcaggaaat tcagttagaa
    20401 atattaggta gtgtttgtca aatactaggc aaaggtggta taataactta tagcacctgc
    20461 actatcgtct cagaggagaa ttttcaagtc gttaaggcct ttttagagag tcatcccgag
    20521 ttcgagcagg taaaactaga acatgaatgt aaggatatca tgaaagacgg ctgtatcctc
    20581 attacacctg aattgtatgg aagtgatgga ttcttcatca gtcaatttcg caagatatcg
    20641 gattaggaag gaactgacac atggaaattt cattattaac agatgttggt cagaaacgaa
    20701 caaataacca agactatgtc aaccactatg tcaatagagc tggacgtacc atgattattt
    20761 tagctgatgg gatgggaggt catcgcgcag ggaatatcgc tagtgaaatg gcggtcacag
    20821 acctgggtgt agcttgggtt gatacccaga tcgatacagt caatgaagtg cgtgaatggt
    20881 tcgcccatta cctagaaatt gaaaatcaaa agattcacca gcttggtcag gatgaagctt
    20941 acagaggcat gggaactact ttggaagtcc ttgctattat tgataatcag gctatctatg
    21001 ctcatattgg tgattcgcgt atcggcttga ttcgtggaga agaataccat cagttgacga
    21061 gtgatcattc tttggttaat gaattgctca aggctggtca attgacacca gaagaggcag
    21121 aagctcatcc gcaaaaaaat attatcaccc agtctattgg gcaaaaagat gaaattcagc
    21181 ctgattttgg gacagttatc cttgagtcag gtgactatct cttgctcaat agtgacggct
    21241 tgaccaacat gatttcaggc agtgagattc gtgatattgt aaccagtgat attcctttag
    21301 cagataaaac ggagacactt gttcgttttg ctaacaatgc aggaggttta gacaacatta
    21361 cggttgccct tgtttctatg aacgaggagg atgaagaatg atccaaatcg gcaagatttt
    21421 tgccggacgc tatcggattg tcaaacagat tggtcgagga ggcatggcgg atgtctacct
    21481 agccaaagac ttaatcttag atggggaaga agtggcagtg aaggttctga ggaccaacta
    21541 ccagacggac ccgatagctg tagctcgttt tcagcgtgaa gcgagagcta tggcagatct
    21601 agaccatcct catatcgttc ggataacaga tattggtgag gaagacggtc aacagtatct
    21661 tgcaatggag tatgttgctg gactagacct caaacgctat atcaaggaac attatcctct
    21721 ttctaatgaa gaagcagtcc gtatcatggg acaaattctc ttggctatgc gcttggccca
    21781 tactcgagga attgttcaca gggacttgaa acctcaaaat atccttttga caccagatgg
    21841 gacggccaag gtcacagact ttgggattgc tgtagccttt gcagagacaa gtctgaccca
    21901 gactaactcg atgttgggct cagttcatta cttgtcacca gagcaggcgc gtggttcgaa
    21961 ggcgactgtg cagagtgata tctatgccat ggggattatt ttctatgaga tgttgacagg
    22021 ccatatccct tatgacgggg atagcgcggt gaccattgcc ctccagcatt tccagaaacc
    22081 cctgccgtcc gttattgcag aaaatccatc tgtacctcag gctttagaaa atgttattat
    22141 caaggcaact gctaaaaagt tgaccaatcg ctaccgctcg gtttcagaga tgtatgtgga
    22201 cttgtctagt agcttgtcct acaatcgtag aaatgaaagt aagttaatct ttgatgaaac
    22261 gagcaaggca gataccaaga ccttgccgaa ggtttctcag agtaccttga catctattcc
    22321 taaggttcaa gcgcagacag aacacaaatc aatcaaaaac ccaagccagg ctgtgacaga
    22381 ggaaacttac caaccacaag caccgaaaaa acatagattt aagatgcgtt acctgatttt
    22441 gttggccagc cttgtattgg tggcagcttc tcttatttgg atactatcca gaactcctgc
    22501 aaccattgcc attccagatg tggcaggtca gacagttgca gaggccaagg caacgctcaa
    22561 aaaagccaat tttgagattg gtgaggagaa gacagaggct agtgaaaagg tggaagaagg
    22621 gcggattatc cgtacagatc ctggcgctgg aactggtcga aaagaaggaa cgaaaatcaa
    22681 tttggttgtc tcatcaggca aacaatcctt ccaaattagt aattatgtcg gccggaaatc
    22741 ttctgatgtt atcgcggaat taaaagagaa aaaagttcca gataatttga ttaaaattga
    22801 ggaagaagag tcgaatgaga gtgaggctgg aacggtcctg aagcaaagtc taccagaagg
    22861 tacgacctat gacttgagca aggcaactca aattgttttg acagtagcta aaaaagctac
    22921 gacgattcaa ttagggaact atattggacg gaactctaca gaagtaatct cagaactcaa
    22981 gcagaagaag gttcctgaga atttgattaa gatagaggaa gaagagtcca gcgaaagcga
    23041 accaggaacg attatgaaac aaagtccagg tgccggaacg acttatgatg tgagtaaacc
    23101 tactcaaatt gtcttgacag tagctaaaaa agttacaagt gttgccatgc cgagttacat
    23161 tggttccagc ttggagttta ctaagaacaa tttgattcaa attgttggga ttaaggaagc
    23221 taatatagaa gttgtagaag tgacgacagc gcctgcaggt agtgtagaag gcatggttgt
    23281 tgaacaaagt cctagagcag gtgaaaaggt agacctaaat aagactagag tcaagatttc
    23341 aatctacaaa cctaaaacaa cttcagctac tccttaaaag cagatggata atcaaaatga
    23401 gtaatcaatc tttgtcatga tttcatggca aagatttttt ttgagtccag atttgtgata
    23461 gaatagaggg agttgataaa aggaggaaag catggaagaa tcaaaagaat taaatgccgt
    23521 cattgatgtg attatgctag cggggactat tctccttaaa agtggctcag aaatccatcg
    23581 tgtagaagat accatgattc gaatcgcgca ttcgcagggg attgtggatt gcaatgtcct
    23641 tgccatgcct gccgctatct ttttctctat tgaaaatacc aatatttcgc gcatgaagcg
    23701 cgtgacctcc tcttcttata acatcgaaaa agtctgcgat gtgaaccaga tttctcgtca
    23761 gctagttggg gggcagattg acttagaaac agcctttaag caattgacgg ccttgcaagc
    23821 tcaacccctt ccctatacta agttgcaggt aactctggct gcgaccttta gtgctccttt
    23881 cttttcagtt atgtttagcg gaaatatcta cgacgcactt ggtgcaggag tggcgacctt
    23941 atttggtttt gccttttccc tctatgtgga aaaatttatc cgaattccct ttgtgacagc
    24001 ctttgctgga gcctttgtct ttgggataat tgcccagttt tgggctcgct acacaggttt
    24061 tccttcaacg gcagatttga ttatagctgg tgcggtcatg ccgtttgtac caggtattgc
    24121 cttgaccaat gcggtccgtg atattatgac caaccacata aactctggta tgagtaagat
    24181 gtttgaatcc ctgctcatta ccctcgcttt aggggcagga acttctgtcg ccttggtatt
    24241 gatgaactaa tatgacacta acaacctttt tattacaagc agtagcaagt tttcttgcca
    24301 ttatcacttt tttaatcgta ctcaatgtgc aacggtctat gctcttacct ggagggattt
    24361 tgggcatgac tgtctggcta atctatctct tgctcaagga accgaccaat gtcattgtag
    24421 ctaccttcat tgcagccatt attggttctt gtgtcagcca gattttaagt attctttata
    24481 agacacctgc tgtggtcttt atcttggcca ttttggcacc gctggttcca ggttatctct
    24541 cctaccgaac aactgccttt tttgtgacag gggactataa taaagcactg gcaagtgcga
    24601 ccttggttgt catgttggct ttggtaatct ctattggaat ggctagcgga acagtgattc
    24661 tcagactgta tcattatata aaaacacatc gagtatcgta gactttacag aaataaaaga
    24721 attttctgaa aaatgagata aataaattaa caacgctttc tatatgtgcg agaataccgc
    24781 acttatgaag aaattgcgac tgattttggt atccacgaaa gcaacttact ccgtcggagc
    24841 caatgggttg aagtaactct tgttcaaagg tggtgttacg atttcaagaa ctcctctcag
    24901 ttctgaagac acggtaatga ttgatgcgac ggaagtaaaa atcaatcgcc ctaaaaaaaa
    24961 caattagcga atgattctgg taaaaagaaa tttcacgcta tgaaggctca agcgattgtc
    25021 acaagtcaag ggagaattgt ttctttggat atcactgtga actattgtca tgatatgaag
    25081 ttgttcaaaa tgagtcgcag aaatatcgga caagctggta aaatcttggc tgacagtggt
    25141 tatcaagggc tcatgaagat atatcctcaa gcacaaactc cacgtaaatc cagcaaactc
    25201 aagctgctaa cagttgaaga taaagcctat aaccatgcgc tatctaagga gagaagcaag
    25261 gttgagaaca tctttgccaa agtaaaaacg tttaaaatgt tttcaacaac ctatcgaaat
    25321 catcgtaaac gcttcggatt acgaatgaat ttgattgctg gcattatcaa tcatgaacta
    25381 ggattctagt tttgcaggaa gtctactact ttccttattg tctgtaaatc tactgacctt
    25441 gttgtttatc ccagtcatgg tttctagttc gggctcagag tttcaaagtg gatggcaaga
    25501 gcatcaattg attgctgaga aggttagtaa aacacttgat aagacatttg ataaggatgt
    25561 cagagaaatt ccgaccagtc agttttatca aaaatttgta gatgagatgg gaaggactta
    25621 ctcaggaaat ttgatcctcc aggagctgat aactgtgaat ggagcttata aagctactta
    25681 tatcggtgaa ctctctagca actaatcatt ctttaaaatg atgaccaata agaggcttga
    25741 tttggtgaat caagtctttt ttctctcttt tactgccatt tgtgataaaa tagtatagaa
    25801 cgatttttta catgaatgat aaaacagagg taaatatgac aatcggtatt gataagattg
    25861 gttttgcgac cagtcaatat gtcttgaaat tacaagactt agcagaagcg aggggaattg
    25921 accctgaaaa attaagtaaa ggactcttac tcaaggaatt gagtattgcg cccctaactg
    25981 aggacatcgt gaccttggcg gccagtgcta gtgactctat tttaactgag caagaaagac
    26041 aagaagttga catggtcatt gtggcgaccg agtcaggaat tgaccagagt aaggctgcgg
    26101 ccgtctttgt gcatggcttg ctgggcatcc agccctttgc tcgtagtttc gagattaaag
    26161 aagcctgcta tggggcgact gctgccctcc attatgccaa attgcatgtg gaaaattctc
    26221 cggagtccaa ggtcttggtc attgcaagtg atattgccaa atacggtatt gaaactccgg
    26281 gagaacccac tcagggtgcc ggaagtgtgg ctatgttgat tacacaaaat ccacgcatga
    26341 tggcctttaa taatgacaat gtagctcaga cccgtgacat catggatttc tggcgaccaa
    26401 attactcgac aactccttat gtaaatggtg tctattctac ccaacaatac ttggatagtt
    26461 tgaaaacgac ttggcttgaa tatcaaaaac gctaccagct tactttggat gattttgcgg
    26521 ctgtttgttt ccacttgcct tatcctaaat tagcgctaaa aggcttgaaa aaaatcatgg
    26581 ataagagcct gcctcaagag aaaaaagacc tcttacaaaa gcattttgac cagtctattc
    26641 tctacagtca aaaggtgggg aatatctaca caggttcact tttccttgga cttttgtctc
    26701 tcttggaaaa tacagatagc ttgaaagctg gggataaaat cgccctttat agttacggaa
    26761 gtggagctgt ggctgagttc ttcagtggtg aattggttga aggatatgaa gcttatttgg
    26821 ataaagaccg cttgaacaag ctcaaccaac gaactgtctt atccgttgca gactatgaaa
    26881 aggtcttttt tgaggaagta aacttggatg aaacaaactc tgcccagttt gctggctatg
    26941 aaaatcaaga ttttgccttg gttgaaattc tcgaccacca acgccgttat agcaaggttg
    27001 aaaaataatg aagataagtt ggaatgggtt ttctaaaaaa tcataccaag agcgcctcga
    27061 gctgttaaaa gctcaggcgc tccttagtcc tgagagacaa gctagtctgg agaaggatga
    27121 acagatgagt gtgactgtgg cagaccagct gagtgagaat gtagtgggaa ctttttctct
    27181 gccttattcg ctggttccgg aggtacttgt caacggtcag gaatacaccg ttccctatgt
    27241 gacagaagaa ccctctgtgg ttgcggcggc cagctatgcc agcaaaatca tcaagcgtgc
    27301 aggtggtttt actgcacaag tccatcagcg ccagatgatt gggcaggtag ccctttatca
    27361 agttgctaat cctaaactag cgcaagagaa gattgccagc aagaaagcgg agctcttgga
    27421 gcttgccaat caagcctatc cttctatcgt taaacgtggg ggtggggcgc gtgacctgca
    27481 tgtcgagcag ataaaaggcg aaccagactt tctcgttgtt tatattcatg tcgataccca
    27541 ggaagccatg ggtgccaata tgctcaacac catgctggaa gccttgaaac cagtcttaga
    27601 agaactcagt cagggacaga gtctcatggg aatcctgtcc aactacgcga ccgattctct
    27661 ggtgactgca agctgtcgca tggcctttcg ctacttgagc cgccaaaagg atcaaggacg
    27721 agagattgcg gagaaaattg cgttggctag tcagtttgcg caggatgatc cttaccgagc
    27781 tgctactcat aataaaggaa tttttaatgg tattgatgcg attttgattg ccactggtaa
    27841 tgactggcgt gccatcgaag ctggggccca tgcctttgcc agtcgagatg gacgctatca
    27901 aggtcttagt tgctggacgc tggaccttga aagagaagaa ttggtcggtg agatgaccct
    27961 gcccatgcct gtagcgacta agggtggctc tatcggcctc aacccacgtg tagctctcag
    28021 tcatgatcta ctaggaaatc cttctgccag agaattagcc cagattatcg tgtctatcgg
    28081 tcttgcccaa aattttgcag ccctcaaagc cttggtaagt acgggcatcc agcaaggcca
    28141 catgaaacta caggccaaat ccctagctct cctagctggg gctagtgaat ctgaagttgc
    28201 tcccctagtc gagcagctta tcgcagataa aacctttaac ctagagacag cccagcgcta
    28261 tctcgaaaat ttaagatcat aaaaaactca gacgaatcgg tctgagtttt cttgtgttta
    28321 aatacttttt cctggtaata gtgtaactgg taagaagtaa ccagttgtgg tgacttcctt
    28381 gccttcaatc ttttgcaaga gaagatcaat agtgagacaa gcaatctctt ccaaaggttg
    28441 cttgatagta gccaattgag ggtagtaatt ttcgataaag taggtcccat catagccgat
    28501 gaccttgagc tcttttggga cagaaatgcc caattcttga gcgattttaa tgaccagaat
    28561 agctgtcaaa tcatccgaag caaaaatggc atctggtttt tcccgggtca agatattctt
    28621 gatttccatt tcttttctga cgggagaaaa gtcactggaa acattgataa taggagcttt
    28681 tgggagtacg gatgcaaaac cagcgtggcg cagtccggtt ggcgaattgg aattgtcatt
    28741 ccctgtaatc atgatgatag actgggcacc tgtcttgacc aaggtttggg cagcaagaac
    28801 cccaccagca tagttgtcag aggagacgac agggatgtct ggcgataggt ttcggtcaaa
    28861 ggaaataatc ggcgctgtca cacgattgta gtcttcgatt cctaggttgt gactaccaga
    28921 aatgatgccg tccacctgat tggcttccaa catttcgatg tattcacgtt ccttctcaga
    28981 atcatgttca ctgttgcaga tgatggtctt gtaaccattt ttgaagagtt ggtgttccaa
    29041 tttatcaatc aattctgcat agaaaacatt ggaaatattg gggaaaatca agccgattaa
    29101 cttagctgat tttccttgca gactacgagc caggttgttg ggtttatagc ccaattctcg
    29161 catggcttca ttgacttttt ggatggtttt ctcagataga tacccttttt tattgataac
    29221 ccgagaaacg gtagtaggac tgacgcctgc aagtttggcg acatcagtta gttttgcgac
    29281 cataatctaa ttcatagtaa gttccagttg ggtttccaga tttgatcagg ataccatttt
    29341 ggtccgcatg tgggaagaca cgaccagaaa atactttttc tcctttattg atgaaaattt
    29401 caaagacaga gttatcgatg aagattgtag cagtagtagc ctgattctcg atagggcaag
    29461 aacgagttgt cccaaattct tgggcatact gttctccagc ctggctacga tccactgtca
    29521 cttgaccgtt tacaaggtca aagttgattg aaagtccctt accttcttta tcagcaagta
    29581 agacaatctc gctctggcta ttagcttcca agttgagttc aagttcgtaa gtgttcttgg
    29641 tttgggaacg gtttgagaag gcttcttcag aagcacgaag gtccttaata gcagcgactg
    29701 gatactggta gagcttgtcg tctttgatag tgagttcctt gaccaaagag aaggttcctt
    29761 ggtggtcaaa acggtcagat gggtaagaaa catctggcaa accaagccag ctaactgcta
    29821 gagcacgccc atcaggagcg ttgaaggctt gagttgcata ggcttcgaaa ccgtaatcca
    29881 tgttttgaag ttgagacaca tctaccattt tggcattttt agggtcaaag gaagccccaa
    29941 tcttatacat atttggaaag atattatcgt agtctagaac tttcttatcc aatccttgtg
    30001 gacagtagag aaggacaggt tgttcctcta caaagaccag attaggacat tccatcatgt
    30061 aggcagtacg gtcgttagca aagtcaaggt cgccaactgc ttgccagttt gtgtagtcgt
    30121 tattgacagc cttgtagaga cgaacgaaac cttttttctc caagtcctgt ccaccgacga
    30181 cagcatagta ttgaccttta aagttaaaaa tttgtggatc gcggaagtgg tcagtagagt
    30241 ctgctggctg gtcaatcaag atcttgtcaa tctttgtaat cttaccctcc ttgtccatca
    30301 aagcaccgat ctggtatggg tgacggatcc agttttcatc gcgaacattt cctgtataaa
    30361 ataggaataa gttatcgcca aattgcatgg cagaaccaga gtaggcaccg tggctatcta
    30421 atggagtatc tggtaaaact ttgattccag tttctttaaa gtgaaccaaa tcatcacttt
    30481 ctagctgtgc ccaagatttt aaaccgtggg ctgcaccaaa aggaaaattc tggtaaaaga
    30541 ggatccactt gccatcaaag taagaaaagc catttgggtc gttgagaagt cctgtttttg
    30601 gctcaacatg gtaatgagta tgccatggag attgtgccat attttccttt atatgttgaa
    30661 tttcttcttg cgtccaatct tgataaagtc tgtaacgacg ctcagttgtc cattccattc
    30721 attcctccaa aaatcttatc acttttaata gtaactgttt tcgataaaaa atgcaagcct
    30781 tttatgttaa aaaagaggaa aaactgtcaa aggattatca taaaataaat acaggaaatc
    30841 aat
//
LOCUS       DAVKEV010000026        29906 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVKEV010000026 DAVKEV010000000
VERSION     DAVKEV010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29906
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.026"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            95..1099
                     /locus_tag="VWZ68_001251"
     CDS             95..1099
                     /locus_tag="VWZ68_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9372276.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPEFVLKEAGQVIE
                     "
     gene            1168..2034
                     /locus_tag="VWZ68_001252"
     CDS             1168..2034
                     /locus_tag="VWZ68_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9372277.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGHMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            2031..2789
                     /locus_tag="VWZ68_001253"
     CDS             2031..2789
                     /locus_tag="VWZ68_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9372278.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFEQDFITILGGN
                     GAGKSTLFNTIAGTISLTSGTIRILGEDVTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLFPRRLASYKDKFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRVIQDLKQEEKAKMKISDYYQLFE"
     gene            2879..4639
                     /gene="dnaG"
                     /locus_tag="VWZ68_001254"
     CDS             2879..4639
                     /gene="dnaG"
                     /locus_tag="VWZ68_001254"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEU9372279.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPYQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRVGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VKEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            4642..5763
                     /gene="rpoD"
                     /locus_tag="VWZ68_001255"
     CDS             4642..5763
                     /gene="rpoD"
                     /locus_tag="VWZ68_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEU9372280.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSRVLSNEEEPELSDEDLIGSTSAKVNDP
                     VRMYLKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQ
                     FLDLIQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVE
                     TINKLVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDD
                     SHLGDFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLE
                     DVGKVFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            5777..6106
                     /locus_tag="VWZ68_001256"
     CDS             5777..6106
                     /locus_tag="VWZ68_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU9372281.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            6221..7264
                     /gene="cpoA"
                     /locus_tag="VWZ68_001257"
     CDS             6221..7264
                     /gene="cpoA"
                     /locus_tag="VWZ68_001257"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEU9372282.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            7280..8605
                     /locus_tag="VWZ68_001258"
     CDS             7280..8605
                     /locus_tag="VWZ68_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU9372283.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            8636..8812
                     /locus_tag="VWZ68_001259"
     CDS             8636..8812
                     /locus_tag="VWZ68_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU9372284.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIVPVATDY"
     gene            8871..9005
                     /locus_tag="VWZ68_001260"
     CDS             8871..9005
                     /locus_tag="VWZ68_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEU9372285.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            9069..10379
                     /gene="obgE"
                     /locus_tag="VWZ68_001261"
     CDS             9069..10379
                     /gene="obgE"
                     /locus_tag="VWZ68_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEU9372286.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            10389..10547
                     /locus_tag="VWZ68_001262"
     CDS             10389..10547
                     /locus_tag="VWZ68_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372287.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(10599..11925)
                     /locus_tag="VWZ68_001263"
                     /pseudo
     CDS             complement(10599..11925)
                     /locus_tag="VWZ68_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            13028..14287
                     /locus_tag="VWZ68_001264"
     CDS             13028..14287
                     /locus_tag="VWZ68_001264"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU9372288.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            14303..14854
                     /locus_tag="VWZ68_001265"
     CDS             14303..14854
                     /locus_tag="VWZ68_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9372289.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            14847..16124
                     /locus_tag="VWZ68_001266"
     CDS             14847..16124
                     /locus_tag="VWZ68_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU9372290.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            16140..17000
                     /locus_tag="VWZ68_001267"
     CDS             16140..17000
                     /locus_tag="VWZ68_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEU9372291.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVIGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            17223..17333
                     /locus_tag="VWZ68_001268"
                     /pseudo
     CDS             17223..17333
                     /locus_tag="VWZ68_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818216.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
     gene            17379..18183
                     /locus_tag="VWZ68_001269"
     CDS             join(17379..17747,17749..18183)
                     /locus_tag="VWZ68_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEU9372292.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESNLLRRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATEVKINRPKKELANDSGKKKCHAMKAQAIVTSQGRIVSLDIAVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTVEDKAYNHA
                     LSKDRSKVENIFAKVKTFKMISTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            18375..20666
                     /gene="pcrA"
                     /locus_tag="VWZ68_001270"
     CDS             18375..20666
                     /gene="pcrA"
                     /locus_tag="VWZ68_001270"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEU9372293.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            20709..21389
                     /gene="radC"
                     /locus_tag="VWZ68_001271"
     CDS             20709..21389
                     /gene="radC"
                     /locus_tag="VWZ68_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEU9372294.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(21386..22075)
                     /locus_tag="VWZ68_001272"
     CDS             complement(21386..22075)
                     /locus_tag="VWZ68_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU9372295.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDSGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELTLIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(22093..22734)
                     /locus_tag="VWZ68_001273"
     CDS             complement(22093..22734)
                     /locus_tag="VWZ68_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEU9372296.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(22817..23032)
                     /locus_tag="VWZ68_001274"
     CDS             complement(22817..23032)
                     /locus_tag="VWZ68_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU9372297.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(23040..23387)
                     /locus_tag="VWZ68_001275"
     CDS             complement(23040..23387)
                     /locus_tag="VWZ68_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEU9372298.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(23392..24507)
                     /locus_tag="VWZ68_001276"
     CDS             complement(23392..24507)
                     /locus_tag="VWZ68_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU9372299.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(24517..25476)
                     /locus_tag="VWZ68_001277"
     CDS             complement(24517..25476)
                     /locus_tag="VWZ68_001277"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU9372300.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGAPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(25589..26158)
                     /locus_tag="VWZ68_001278"
     CDS             complement(25589..26158)
                     /locus_tag="VWZ68_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEU9372301.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            26286..26957
                     /locus_tag="VWZ68_001279"
     CDS             26286..26957
                     /locus_tag="VWZ68_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEU9372302.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            26941..27759
                     /locus_tag="VWZ68_001280"
     CDS             26941..27759
                     /locus_tag="VWZ68_001280"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEU9372303.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            27756..28652
                     /locus_tag="VWZ68_001281"
     CDS             27756..28652
                     /locus_tag="VWZ68_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU9372304.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHLLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            28696..29670
                     /gene="pta"
                     /locus_tag="VWZ68_001282"
     CDS             28696..29670
                     /gene="pta"
                     /locus_tag="VWZ68_001282"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEU9372305.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT         8948 a         5357 c         6703 g         8898 t
ORIGIN      
        1 atttttttga tggaggttag tatagaaaga aaacgatggc gtcgcttgtt tagataagtg
       61 aaatatgtta aaggaaataa aaaggagaaa cagaatgaaa aataaacgtt taattggaat
      121 tattgctgca ttagcagtct tagtagcagg aagcttgatt tattcttcaa tgaataaatc
      181 agaagctcag aataataagg atgagaagaa aataaccaag attggtgtgc ttcaatttgt
      241 gagccatcca tcccttgatt tgatttataa agggatccaa gatggacttg cagaagaagg
      301 atataaagat gatcaagtta aaattgattt tatgaactca gaaggtgacc aaagtaaggt
      361 tgcgacaatg agtaaacaat tggttgcaaa tgggaatgac cttgtggttg gtatcgcaac
      421 accagcagcc caagggttgg ctagtgcaac aaaagaccta ccggttatca tggccgctat
      481 tacagaccca attggtgcta acttggttaa agatttgaaa aaaccaggtg gcaacattac
      541 aggggtatct gaccacaatc cagctcaaca acaagttgaa ctcatcaagg ctctgacacc
      601 gaatgtgaaa acaatcggag ctctttactc aagtagcgaa gacaattcaa aaacacaggt
      661 cgaagaattt aaggcttatg ctgaaaaagc aggtctgaca gtggaaacat ttgcagttcc
      721 ttcaacaaat gaaattgcct caactgtcac tgttatgact agcaaggtag atgctatttg
      781 ggttccaatt gataacacca ttgcatcagg atttccaacg gttgtctcta gcaatcaaag
      841 ttctaagaaa ccaatttatc ccagtgcgac agctatggta gaagtaggtg gtttggcatc
      901 agttgtaatt gaccaacatg accttggtgt ggcaacaggt aaaatgattg tgcaagtctt
      961 gaaaggtgca aaaccagccg ataccccagt caatgtcttt tcaactggta agtcagtcat
     1021 caataaaaaa atagcacaag aactaggtat tactattcct gagtttgttc tcaaagaagc
     1081 aggacaagtc atcgaataaa taaggtaggg aggaggagac tcttcccatt ttttaaaaag
     1141 atgaatatag aaaggattaa ataaaatatg attgtttcca ttatttctca aggatttgtc
     1201 tgggctattc taggtctggg aatctttatg acatttagga ttttaaactt tccagatatg
     1261 acgacagaag gttccttccc tcttggggga gctgttgctg tcactttgat aaccaaaggc
     1321 gtgaacccat ttttagcgac acttgttgct gtaggagcag gttgtttggc tggaatggca
     1381 gcaggccttc tttatacaaa agggaagatc ccaaccttgc tctcagggat tttggtgatg
     1441 acttcttgtc actcaatcat gctcttgatt atgggacgtg caaatttagg cctgcttgga
     1501 accaagcaaa ttcaggatgt tttgcctttt gattcggatt tgaatcaact cttgacaggt
     1561 ctcatctttg tgagtattgt tattgctctc atgctctttt tcttggacac taaactcgga
     1621 caagcctata ttgctacagg ggataatcct gatatggcta gaagtttcgg gattcatact
     1681 ggacacatgg agctcatggg cttggtctta tcaaatggtg tgattgccct tgcaggtgcc
     1741 ctcattgctc agcaagaagg ttatgccgat gtgtctcgag ggatcggggt tatcgttgtg
     1801 gggcttgcaa gtttgattat tggagaagtt attttcaaga gtttgagctt ggcagagcgt
     1861 ttggttacta tcgttgtagg ttctatcgct tatcaatttt tagtgtgggc agttatcgca
     1921 cttggcttta atacaagtta ccttcgttta tacagtgcct tgattttagc agtctgcctc
     1981 atgattccaa catttaagca aacaatcttg aaaggagcca agttaagcaa atgacagcaa
     2041 ttgtagaatt aaaaaatgca accaaaatcg ttaaaaatgg ctttgatgaa gaaaagatta
     2101 ttttaaatga tgtttcctta gaaatttttg aacaggactt tatcacgatt ttgggtggaa
     2161 atggtgctgg taaatcaacc ctctttaaca ctattgcagg aaccatatca ctaaccagtg
     2221 gaactatccg tattttaggt gaggatgtta ccaagttttc accagagaag cgcgctaagt
     2281 atctgtctcg agtcttccaa gatccaaaga tggggacagc tcctcgtatg acagtggcag
     2341 agaatctcct gattgccaag tttcgtggtg aaaagcgtgg actatttccg agacgtctgg
     2401 ctagctataa ggataagttt caggcgacca ttgaaaaagt gggaaacggt cttgagaaac
     2461 acttgaatac accgattgag ttcttatctg gtggacaaag acaggctttg agtctcttga
     2521 tggcaacctt gaagcgacct gaattactct tgttagacga gcatactgct gccctggatc
     2581 caaagactag tgttgctttg atggaattga cagatgaatt tgttaagaaa gatcaattga
     2641 cagcccttat gattacccat catatggaag atgctctcaa atatggcaat cgcttgattg
     2701 tcatgaaaga aggacgggtt atccaagatt tgaaacaaga agaaaaagca aaaatgaaaa
     2761 tctctgatta ttatcaactc tttgaataaa gtagggaaaa tgagtgaaat ggtttacttt
     2821 ttttctgaaa taaagtatac tatataaagt aaactatgat aacatggagg tattgtgtat
     2881 ggttgacaaa caagtcattg aagaaatcaa aaacaatgcc aacattgtgg aagtcatagg
     2941 agatgtgatt tctttacaaa aggcaggacg gaactatcta gggctctgtc cttttcatgg
     3001 tgaaaaaaca ccttctttca acgttgtaga ggacaagcag ttttaccact gttttggttg
     3061 tggtcgctca ggtgatgtct ttaaattcat cgaggagtac caaggggtta cctttatgga
     3121 ggctgtccaa atcttaggtc agcgtgtcgg gattgaggtt gaaaaaccgc tttatagtga
     3181 acagaagcca gcctcgcctt accaagctct ttatgatatg cacgaagatg cggctaaatt
     3241 ttaccatgct attctcatga caacgactat gggcgaagag gccagaaatt acctttatca
     3301 gcggggtttg acagatgaag tgcttaaaca tttttggatt ggtttagcac ctccagaacg
     3361 aaactatctc tatcaacgtt tgtctgatca gtatcgtgaa gaggatttac tggattcagg
     3421 cctgttttat ctctcggatg ccaatcaatt tgtagacacc tttcacaatc gcattatgtt
     3481 tcccctgaca aatgaccaag gaaaggtcat tgccttctca ggtcgtatct ggcaaaaaac
     3541 ggattcacaa acttctaagt ataaaaacag ccgatcgact gcaattttta acaaaagtta
     3601 cgaattatat catatggata gggcaaaaaa atcttctgga aaagctagtg agatttacct
     3661 gatggaagga ttcatggatg ttattgcagc ctatcgggtt ggaatcgaaa atgctgtggc
     3721 gtcgatggga acggccttga gtcgagagca tgttgagcat ctgaaaaggt taaccaagaa
     3781 attggttctt gtttacgatg gagataaggc tgggcaagcc gcgatattga aagcattgga
     3841 tgaaattggt gatatgcctg tgcaaatcgt cagcatgcct gataacttgg atcctgatga
     3901 gtatctacaa aaaaatggtc cagaagactt ggcctatcta ttaacgaaaa ctcgtattag
     3961 tccgattgag ttctacattc atcagtacaa acctgaaaac agtgaaaatc tgcaggctca
     4021 gattgagttt attgaaaaaa tagctccctt gattgttaaa gaaaagtcca tcgctgctca
     4081 aaacagctat attcatattt tagctgacag tctggcgtcc tttgattatg cccagattga
     4141 gcagattgtt aatgagagtc gtcaggtgca aaggcagaat cgcatggaaa gaatttccag
     4201 accgacgcca atcaccatgc ctgtcaccaa gcagttatcg gctattatga gggcagaagc
     4261 ccatctactc tatcggatga tggaatcccc tcttgttttg aacgattacc gtttgcgaga
     4321 agactttgca tttgctacac ctgaatttca ggtcttatat gacttgcttg gccagtatgg
     4381 aaatcttcct ccagaagttt tagcagagca gacagaggaa gttgaaagag cttggtacca
     4441 agttttagct caggatttgc ctgctgagat atcgccgcag gaacttagtg aagtagagat
     4501 gactcgaaac aaggctctct tgaatcagga caatatgaga atcaaaaaga aggtgcagga
     4561 agctagccat gtaggagata cagatacagc cctagaagaa ttggaacgtt taatttccca
     4621 aaagagaaga atggagtaat aatggcaaca aaacaaaaag aagtaacaac atttgacgta
     4681 caggtagcag aatttatccg taatcataag caaaaaggga cagcaacaga tgatgaaatc
     4741 aatgcaagtc tggttattcc ttttaccttg gacgctgatg ggattgaaga tctcttgcaa
     4801 cggattcagg atgcaggcat ttctatcaca gataacgaag gaaatccaag tgcgcgtgtt
     4861 cttagccgtg ttcttagcaa tgaagaagaa ccagaactca gcgatgagga cttgattggg
     4921 tcaacttctg ctaaggtcaa tgaccctgtc cgtatgtact tgaaagaaat aggggtcgtt
     4981 cctctcttga ccaatgaaga ggagaaagag ttggcactgg ctgttgaagc tggcgatatc
     5041 gaagccaaac aacgtcttgc ggaagccaat cttcgtttgg ttgtttccat tgccaaacgc
     5101 tatgtcggtc gtggcatgca gttccttgac ttgattcaag aaggaaatat gggcttgatg
     5161 aaggcggttg acaagtttga ctattctaaa gggttcaagt tttcaactta tgcaacttgg
     5221 tggattcgtc aggctatcac tcgtgctatt gcggaccaag ctcgtaccat ccgtatccca
     5281 gttcacatgg ttgaaactat caataaattg gttcgtgaac agcggaatct ccttcaagaa
     5341 ttggggcaag atccgacacc agaacagatt gctgaacgaa tggatatgac acctgataag
     5401 gttcgtgaaa tcttgaagat tgcccaagaa ccagtatctc ttgaaactcc tatcggtgaa
     5461 gaggacgata gccaccttgg agactttatc gaagatgaag tgattgaaaa tccagtggat
     5521 tatacgactc gtatcgtctt gcgtgagcaa ttggatgaaa tcttagatac tcttacagac
     5581 cgtgaagaaa atgttctgcg tctacgtttt ggactagatg atggaaaaat gcgcacactt
     5641 gaagatgtgg ggaaagtctt taacgtaact cgtgagcgta tccgtcagat tgaagcaaag
     5701 gctttgagaa aactacgcca accaagtcgc agcaaaccgc ttcgtgattt tattgaagac
     5761 taagagtgag gaaaatatgg cttatacaga agagcaaatt gaaaacatca aaacacggat
     5821 tttaacagcc ttggaagaag tcatcgaccc tgagttggga atcgatattg tcaatcttgg
     5881 tttgatctat gagattcgtt ttgacggtga cacagggcaa acagagattg acatgacttt
     5941 gacaactatg ggttgtccct tagcagacct tttgacagac cagatttatg atgctatgat
     6001 agaggttcca gaagtaacgg atactgaggt taaattagtc tggtatccag cctggacagt
     6061 tgaaaaaatg agtcgctatg cccgcattgc cctaggcatt aagtaaacat ataaaagcat
     6121 gtgagagact gttggaaaag cgaggaaatt tcccctcttt tcctctagtc tctcctttct
     6181 tttgctgatt ttattcaaag aaaatgatat aatagtagtt atggagaaaa agaaattacg
     6241 catcaatatg ttgagttcaa gtgagaaagt agcaggacag ggagtttcag gtgcttaccg
     6301 tgaattagtt cgtcttcttc accgtgctgc caaggaccaa ttgattgtta cagaaaatct
     6361 tccgatcgag gcagatgtga ctcactttca tacgattgat tttccctatt atttatcaac
     6421 cttccaaaag aaacgctcag ggagaaagat tggctatgtg catttcttgc cagctacact
     6481 tgagggaagt ttgaaaattc catttttctt aaagggaatt gtgaaacgct atgtattttc
     6541 tttttacaac cggatggagc acttggttgt ggtcaatcct atgtttattg aggatttggt
     6601 agcagctggt attccacgtg aaaaagtgac ctatattcct aactttgtca acaaggaaaa
     6661 atggcatcct ctaccacaag aagaggtagt cagactgcgc acagatcttg gtcttagtga
     6721 caatcagttt atcgtagtag gtgctgggca agttcagaaa cgtaaaggga ttgatgactt
     6781 tatccgtctg gctgaggaat tgcctcagat tacctttatc tgggctggtg gcttctcttt
     6841 tggtggtatg acagatggtt atgaacacta taagaaaatt atggaaaatc cccctaaaaa
     6901 tttgattttt ccaggcattg tatcgccaga gcggatgcgc gaattgtatg ctctagcgga
     6961 tcttttcttg ttgcctagtt acaatgagct ctttcctatg actattttag aagctgcgag
     7021 ttgtgaggct cctattatgt tgcgtgattt agatctctat aaggtgattt tggagggaaa
     7081 ttatcgggcg acagcgggta gagaagagat gaaagaggct attttggaat atcaagcaaa
     7141 tcctgctgcc ttaaaagatc tcaaagaaaa ggctaagaat atttccagag agtattctga
     7201 agagcatctg ttacaaatct ggttggactt ttatgagaaa caagccgctt tagggagaaa
     7261 gtaaaaagtg aggtaatcta tgcgaattgg tttatttaca gatacctatt ttcctcaggt
     7321 ttctggtgtt gcgaccagta ttcgaacctt gaaaacagaa cttgaaaagc agggacatgc
     7381 tgtttttatc tttacgacga cagataagga tgtcaatcgc tacgaagatt ggcaaattat
     7441 ccgcattcca agtgttcctt tctttgcttt taaggatcgt cgctttgcct accgaggttt
     7501 tagcaaggca cttgaaattg ctaaacagta tcagctagat attatccata ctcagacaga
     7561 attttctctt ggcctgttgg ggatttggat tgcgcgtgaa ttgaaaattc cagtcatcca
     7621 tacctatcac acccagtatg aagactatgt ccattatatt gctaagggga tgttgatccg
     7681 accgagtatg gtcaagtatc tggttagagg tttcctgcat gatgtggatg gggttatttg
     7741 ccctagtgag attgtccgtg acttgctatc tgattataag gtcaaggttg aaaaacgggt
     7801 cattcctact gggattgaat tagccaagtt tgagcgtccg gaaatcaagc aggaaaattt
     7861 gaaagaactg cgtagtaaac tagggattca agatggtgaa aagacgttgc ttagtctttc
     7921 gagaatctcc tatgaaaaaa atattcaagc agttttagta gcctttgctg atgttctgaa
     7981 agaggaagac aaggttaaac tggtagtagc tggggatggc ccttatctga atgacctcaa
     8041 agagcaagcc cagaacctag agattcaaga ctcagtcatc tttacaggga tgattgctcc
     8101 tagtgagacg gctctttact ataaagcggc ggattttttc atttcggcat cgacaagcga
     8161 aacgcaaggt ttgacctact tggaaagctt agccagtgga acacctgtca ttgctcacgg
     8221 aaatccttat ttgaacaacc tcatcagtga taaaatgttt ggaaccttgt actatggaga
     8281 acatgatttg gctggtgcta ttttggaagc cctgattgca acaccagaca tgaacgagca
     8341 taccttatca gagaaattgt atgagatttc agctgagaac tttgggaaac gagtgcatga
     8401 gttttatctg gatgccatta tttcaaataa cttccagaaa gatttggcta aagatgatac
     8461 ggtcagtcag cgtatcttta agacagtttt gtatcttcag caacaggtgg ttgctgtacc
     8521 tgtaaaagga tctagacgca tgttgaaggc ttcaaaaaca cagttgatca gtatgagaga
     8581 ctattggaaa gaccatgaag aatagaaaga ggaacagcta tgaaaaaaac aattaatgag
     8641 aagcggtcgt gataaaaaga ttgcgggtgt ttgtgctggg gtggcccatt atctggatat
     8701 ggatccgact atcgttcaag tcatttgggg tgttcttact tgctgttacg gagctggaat
     8761 tgtagcttac attattttat ggattatcgt accagtagca actgactatt gaaaactagc
     8821 tcaattcatg ctaagataat agaaaataga atgtaacgaa ggagagaaaa atggcatttg
     8881 gagataatgg aaatcgtaaa aaaactatgt ttgagaaaat aaccttgttt atcgtgatta
     8941 tcatgctagt agcaagttta ttgggaattt ttgcaactgc aattggtgcc ctcagtaatc
     9001 tataaaatag attcaagaaa atttagtgac tgggatttcc cagccctttt ttaaagtgag
     9061 aagaaataat gagtatgttt ttagatacag ctaagattaa ggtcaaggct ggtaatggtg
     9121 gcgatggtat ggttgccttt cgtcgtgaaa aatatgtccc taatggaggc ccttggggtg
     9181 gtgatggtgg tcgtggaggc aatgtggtct tcgttgtaga cgaaggatta cgtaccttga
     9241 tggatttccg ctacaatcgt catttcaagg ctgattctgg tgaaaaaggg atgaccaaag
     9301 ggatgcatgg tcgtggtgct gaggacctta gagttcgagt accacaaggt acgactgttc
     9361 gtgatgcgga gactggcaag gttttaacag atttgattga acatgggcaa gaatttatcg
     9421 ttgcccacgg tggtcgtggt ggacgtggaa atattcgttt cgcgacacca aaaaatcctg
     9481 caccggaaat ctctgaaaat ggagaaccag gtcaggaacg tgagttacaa ttggaactaa
     9541 aaatcttggc agatgtcggt ttagtaggat tcccatctgt agggaagtca acacttttaa
     9601 gtgttattac ctcagctaag cctaaaattg gtgcctacca ctttaccact attgtaccaa
     9661 atttaggtat ggttcgcacc caatcaggtg aatcctttgc agtagccgac ttgccaggtt
     9721 tgattgaagg ggctagtcaa ggtgttggtt tgggaactca gtttctccgt cacatcgagc
     9781 gtacacgtgt tatccttcac atcattgata tgtcagctag cgaaggccgt gatccatatg
     9841 aggattacct agctatcaat aaagagctgg agtcttacaa tcttcgcctc atggagcgtc
     9901 cacagattat tgtagctaat aagatggata tgcctgagag tcaggaaaat cttgaagaat
     9961 ttaagaaaaa attgtctgaa aattatgatg aatttgaaga gttaccagct atcttcccaa
    10021 tttctggatt gaccaagcaa ggtctggcaa cacttttaga tgctacagct gaattgttag
    10081 acaagacacc agaatttttg ctctacgacg agtccgatat ggaagaagaa gcttactatg
    10141 gatttgacga agaagaaaaa gcctttgaaa ttagtcgtga tgacgatgcg acatgggtac
    10201 tttctggtga aaaactcatg aaactcttta atatgaccaa ctttgatcgt gatgaatctg
    10261 tcatgaaatt tgcccgtcag cttcgtggta tgggggttga tgaagccctt cgtgcgcgtg
    10321 gagctaaaga tggggatttg gtccgcattg gtaaatttga gtttgaattt gtagactagg
    10381 agactggtat gggagataaa ccgatatctt tccgagatgc ggatggtaat tttgtttccg
    10441 ccgcagacgt ttggaatgaa aagaaattgg aagaactatt taatcgtctc aatccaaatc
    10501 gtgccttgag attggcacga actaaaaagg aaaatccatc tcagtaaaga agctaaaaaa
    10561 tcccggctct ttgtcaactg tagtgggttg aagaaaagct aagctcgaga aaggacaaat
    10621 tttgtccttt cttttttgat attcagagcg atgaaaatcc gttttttgaa gttttcaaag
    10681 tttcgaaaac caaaggcatt gcgcttgata agtttgatga gattattggt cgcttccagt
    10741 ttggcattag aatagtgtag ttgaagggcg ttgacaatct tttctttatc tttgaggaag
    10801 gttttaaaga cagtctgaaa aataggatga acctgcttaa gattgtcctc aataagtccg
    10861 aaaagtttct ctggttcctt attctggaag tgaaaaagca agagctgata gagctgatag
    10921 tgatgtttca agtcttccga atagctcaaa agcttgttta aaatctcttt attggttaaa
    10981 tgcatacgaa aagtaggacg ataaaaacgt ttatcactca gtttacggct atcctgttga
    11041 atgagtttcc agtagcgctt gatagccttg tattcatggg attttcgatg aaactgattc
    11101 atgatttgga cacgcacacg actcatagca cggctaagat gttgtacaat gtgaaagcga
    11161 tcaagaacga ttttagcatt cgggagtgaa acagtctggg agactgtttc agcctgagcc
    11221 tagaaatttg aaagcgaagc tgtttagcca agccatagta agggctaaac atatccatgg
    11281 taatgatttt gacgcgacat cggacggctc tatcatattt aagaaagtga tctcggatga
    11341 cagcttgtgt tctgccttca agaacagtga tgatattgag attgttaaaa tcttgcgcaa
    11401 taaagctcat ctccatctcc cgattgaaac agtcactccc cggactgttt caacgtccca
    11461 ggacataatc tcaggaagac aagaaaaatc atgtttaaag tgaaaatcat tgagcttacg
    11521 aataacagtt gaagttgaaa tggccagctg atgagcaata tcggtcatag aaatcttctc
    11581 aatcaacttt tgcgcaattt tttggttgat aatacgagga atttggtgat ttttcttgac
    11641 gatagaagtt tcagcgacca tcatttttga acagtgatag cacttgaatc gacgctttct
    11701 aaggagaatt ctagtaggca taccagttgt ctcaaggtaa ggaatcttag acggtttttg
    11761 aaagtcatat ttcttcaatt ggtttccgca ctcagggcaa gatggtgcgt cgtagtccag
    11821 tttggcgatg atttccttgt gtgtatcttt attgatgatg tctaaaatct ggatattagg
    11881 gtctttaatg tctagtaatt ttgtgataaa atgtaattgt cccatatgaa tctttctaat
    11941 gagttgtttt gtcgcttttc attatagatc ttatgggatt ttgtggtacg acaggcatgt
    12001 atagcaaact gaatctggaa tagcacagca tatcttctaa aatattgtta taaattgatt
    12061 tgaatttcaa aattaaattg tttgattctt atttcaattt gttatagtat atctgatgtc
    12121 aaagttctcg gcgaatcaaa tagcgattcc caagcctgac tatcgtgagg tagcggatta
    12181 aaatggtctg gggatagacc gttttaagtc tgacgctgga aataagaatt gtcagaagaa
    12241 gggatagcga aatcgtggct ctacgaacag gaacgtgata ataaggcgta tatagcggat
    12301 aagagggcct caaactctaa agtccaaaaa ggtagtcgta acctatatgc gtaaatcacg
    12361 agagtaattg aattcgtact aagattttct attttcactg taacctttta acgtcctcat
    12421 atcttgtata cacgaggaaa gatgtacgac ttatcccgtg aggtctatca ctataaagag
    12481 aaaacgacag atagaagtga tcctgagtca cggttatctt taaaatagat tgtctgatag
    12541 gatgctagcc tgaaaacgtc ttgttcatga aatataggac ggtatgtata aaacgcttct
    12601 gtgaactgag agaaggggga gaagttcttg ctaaaattta gttgaacagc cgtattccga
    12661 tatttagata agagatctag tcttagctcc tactcggttt caggggataa aaaaggggca
    12721 atagcgattc gagaaagatt atactcttcg aaaatctctt caaatcacgt caatatcgcc
    12781 ttgccgtacg tgtaggatac tgactacgtc agttccatct acaacctcaa aacagtgttt
    12841 tgagcaacct gcggctagtt tcctagtgtg atctttgatt tttattgagt attagtaatt
    12901 cagttactaa ctcgtcaact ctgatttatc caataaaatt gaaaaggatg gaaaaaagga
    12961 taaatttatg atatacttta ttttgaagac cttattagaa atcttgaaag agtattgaaa
    13021 acttagaatg agaaaaattg ttatcaatgg tggattacca ctgcaaggtg aaattactat
    13081 tagtggtgct aaaaatagtg ttgtggcctt aattccagct attatattgg ctgatgatgt
    13141 ggtgactttg gattgtgttc cagatatttc ggatgtagcc agtcttgtcg aaatcatgga
    13201 attgatggga gctactgtta agcgttatga cgatgtcttg gagattgatc caagaggtgt
    13261 tcaaaatatt ccaatgcctt atggtaaaat taacagtctt cgtgcatctt attattttta
    13321 tgggagcctc ttaggccgtt ttggtgaagc gacagttggt ctaccgggag gatgtgatct
    13381 tggtcctcgt ccgattgact tacaccttaa ggcgtttgaa gctatgggtg ccactgctag
    13441 ctacgaggga gataacatga agttatctgc taaagataca ggacttcatg gtgcaagtat
    13501 ttacatggat acggttagtg tgggagcaac gattaatacg atgattgctg cggttaaagc
    13561 aaatggtcgt actattattg aaaatgcagc ccgtgaacct gagattattg atgtagctac
    13621 tctcttgaat aatatgggtg cccatatccg tggggcagga actaatatca tcattattga
    13681 tggtgttgaa agattacatg ggacacgtca tcaggtgatt ccagaccgca ttgaagctgg
    13741 aacatatata tctttagctg ctgcagttgg taaaggaatt cgtataaata atgttcttta
    13801 cgaacacctg gaagggttta ttgctaagtt ggaagaaatg ggagtgagaa tgactgtatc
    13861 tgaagacagc atttttgtcg aggaacagtc taatttgaaa gcaatcaata ttaagacagc
    13921 tccttaccca ggctttgcaa ctgatttgca acaaccgctt acccctcttt tactaagagc
    13981 gaatggtcgt ggtacaattg tcgatacgat ttacgaaaaa cgtgtaaatc atgtttttga
    14041 actagcaaag atggatgcgg atatttcgac aacaaatggt catattttgt acacgggtgg
    14101 acgtgattta cgtggggcca gtgttaaagc gaccgactta agagctgggg ctgcactagt
    14161 cattgctggg cttatggctg aaggtaaaac tgaaattacc aatatcgagt ttatcttacg
    14221 tggttattct gatattatcg aaaaattacg taatttagga gcggatatta gacttgttga
    14281 ggattaaacc gtagaggtgt ttatgaatat ttggaccaaa ttagcaatgt tttctttttt
    14341 tgaaacggat cgcttgtatt tgcgtccttt cttttttagt gatagtcagg acttccgcga
    14401 gatagcttca aatccagaaa atcttcaatt tatttttcca acgcaggcaa gtctggaaga
    14461 aagtcaatat gcactggcca attactttat gaagtcccct ttgggagtgt gggcaatttg
    14521 tgaccagaaa aatcaacaaa tgattggttc tattaaattt gagaagttag atgaaatcaa
    14581 aaaagaagct gagcttggct attttttgag aaaagatgct tggtcgcaag gatttatgac
    14641 agaggttgtt agaaaaattt gtcagctttc ttttgaggaa tttggcttaa aacaattatc
    14701 tatcattacc caccttgaaa atgaagctag ccaaagagtt gctcttaagt ctggatttag
    14761 tttgttccgt cagtttaagg gaagtgatcg ttacacaaga aaaatgcggg attatcttga
    14821 atttcggtat gtaaaaggag agttcaatga gtaagcatca ggaaattcta agctatttgg
    14881 aggaattacc agtaggtaaa agggtcagtg ttcgtagcat ttcgaatcat ctaggagtta
    14941 gtgatggaac agcctatcgg gctattaaag aagctgaaaa ccgtggaatt gtggagaccc
    15001 gtcctagaag tggaacaatt cgtgttaaat cccagaaagt tgctatagag agattaacgt
    15061 ttgctgaaat tgcagaagtg acttcttctg aggttctggc tgggcaagaa ggtttagaga
    15121 gagaatttag taagttttca attggtgcca tgactgaaca aaatatcttg tcttaccttc
    15181 atgatggggg gctcttgatt gtcggagacc gaacccgtat tcagttgcta gccttggaaa
    15241 atgaaaatgc agttctggtt acagggggat ttcaggttca tgatgatgtg cttaaactgg
    15301 ccaatcaaaa agggattcct gttctaagaa gtaagcatga tacctttacc gtcgcgacca
    15361 tgatcaataa agccttgtca aatgtccaaa tcaagactga tattctgaca gttgagaaac
    15421 tttatcgccc tagtcatgag tatggttttc tgagagagac agatacagtt aaagattatt
    15481 tggacttggt tcgtaagaat cgtagcagcc gtttccctgt tatcaatcaa catcaggtcg
    15541 ttgttggcgt tgtaaccatg agagacgctg gtgataaatc accaagcacg acaattgata
    15601 aggttatgtc tcgtagtcta tttttggttg gattatcgac aaatattgcc aatgtgagtc
    15661 aacggatgat cgcagaagac tttgaaatgg taccagttgt tcgaagcaat caaactttgc
    15721 ttggcgttgt gacgcgacga gatgtcatgg agaagatgag ccgttcccaa gtttcggctc
    15781 taccaacttt ttctgagcag attggacaaa agctctctta tcaccatgat gaagtagtca
    15841 ttacagtgga accctttatg ctagaaaaaa atggagtttt ggctaatggt gtattggcag
    15901 aaattctgac ccacatgacc caagatttag ttgttaatag tggtcgcaat ctcattatcg
    15961 agcagatgct gatctacttt ttgcaggctg ttcagataga tgatatattg cgcattcagg
    16021 cacggattat tcatcatacg agacggtcag ctataattga ttacgatatt tatcatggtc
    16081 accagattgt ttcaaaagca aatgtgactg ttaaaattaa ttagaaacta ggagaaaaga
    16141 tgataacatt aaaatcagct cgtgaaatcg aagctatgga caaggctggt gattttctag
    16201 caagtattca tataggctta cgtgatttga ttaagccagg cgtagatatg tgggaagttg
    16261 aagaatatgt ccgccgtcgt tgtaaagaag aaaatttcct tccacttcag attggggttg
    16321 acggtgccat gatggactat ccttatgcta cctgttgctc tcttaacgat gaagtggctc
    16381 acgctttccc tcgtcattat atcttgaaag atggtgattt gctcaaagtt gatatggttt
    16441 tgggaggtcc cattgctaaa tctgacctga atgtctcaaa attaaacttc aacaatgttg
    16501 aacaaatgaa aaaatacact cagagctatt ctggtggttt agcagactca tgttgggctt
    16561 atgctgttgg tacaccgtcc gaagaagtca aaaacttgat ggatgtaacc aaagaagcta
    16621 tgtacaaggg tattgagcaa gctgttattg gaaatcgtat cggtgatatc ggtgcggcta
    16681 ttcaagaata cgctgaaagt cgtggttacg gtgtagtgcg tgatttggtt ggtcatggtg
    16741 ttggcccaac tatgcacgaa gaaccaatgg ttcctaacta tggtattgca ggtcgtggac
    16801 tccgtcttcg tgaaggaatg gtcttaacca ttgaaccaat gatcaataca ggcgattggg
    16861 aaattgatac agatatgaaa actggttggg cgcataagac cattgacggt ggattgtcat
    16921 gtcagtatga acaccaattt gtcattacga aagatggacc tgttatcttg actagccaag
    16981 gtgaagaagg aacttattaa taaaaagtga aaagactact ggaagtttat tatgaaaaaa
    17041 tccagtagat cttttcataa taaaacgcat tgtatcaagt gttaggggct gatatcatgc
    17101 gtttttctgc ttttaagatt ttttccaact ctgtttgtaa gcgcatcata acaaagggtc
    17161 taggattcag ggctctcctc ctatatacta ttagtaaagt aaaactaagg gaggatattt
    17221 tagtgtcgca gtctattgtt cctgtagaga ttccacaata ttgtcgtttt gattctaaaa
    17281 agagaaatgg aattctgttt aatgttcgta ttgccaatct taaatttacc ttttttagat
    17341 tagacttcct gcgaaacaaa atatggtata gtagttccat gaattatgaa gcaagtaaac
    17401 aactaactga tgcacgattt aagcgtcttg ttggtgttca gcgtaccact tttgaagaga
    17461 tgttagctgt attaaaaaca gcttatcaac ttaaacacgc aaaaggtgga cgaaaaccta
    17521 aattaagcct agaagacctt cttatggcca ctcttcaata tgtgcgagaa tatcgaactt
    17581 atgaacaaat tgcggctgat tttggtattc acgaaagcaa cttactccgt cggagccaat
    17641 gggttgaagt aactcttgtt caaagtggtt ttacgatttc aagaactcct ctcagttctg
    17701 aggacacggt aatgattgat gcgacggaag taaaaatcaa tcgccctaaa aaaagaatta
    17761 gcgaatgatt ctggtaaaaa gaaatgccac gctatgaagg ctcaagcgat tgtcacaagt
    17821 caagggagaa ttgtttcttt ggatatcgct gtgaactatt gtcatgatat gaagttgttc
    17881 aaaatgagtc gcagaaatat cggacaagct ggaaaaatct tggctgacag tggttatcaa
    17941 gggctcatga agatatatcc tcaagcacaa actccacgta aatccagcaa actcaagccg
    18001 ctaacagttg aagataaagc ctataaccat gcgctatcca aggatagaag caaggttgag
    18061 aacatctttg ccaaagtaaa aacgtttaaa atgatttcaa caacttatcg aaatcatcgt
    18121 aaacgtttcg gattacgaat gaatttgagt gctggtatta tcaatcatga actaggattc
    18181 tagttttgca ggaagtctat tgaggtattg agctagttta tgaaaaaatt gggtgaaaaa
    18241 gtcgagtgtt ttagaaaccc acagtgtagt attctagttt caatccacta tattttgcta
    18301 ctccccgtaa agtttctatt ttccctgatt tctgatataa tagaaatatt gacttcaaga
    18361 gtaaggaaga gaagatgaac gcattattaa atggaatgaa tgaccgtcag gctgaggcgg
    18421 tgcaaacgac agaaggtccc ttgctaatca tggcaggggc tggttctgga aagactcgtg
    18481 ttttgaccca ccgtatcgct tatttgattg atgaaaagct ggtcaatcct tggaatatct
    18541 tggccattac ctttaccaac aaggctgcgc gtgagatgaa agagcgtgct tatagcctca
    18601 atccagcgac tcaggactgt ctgattgcga ccttccactc catgtgtgtg cgtattttgc
    18661 gtcgcgatgc ggaccatatt ggctacaatc gtaattttac aattgtggat cctggtgaac
    18721 agcgaacgct catgaaacgt attctcaaac agttgaactt ggatcctaaa aaatggaatg
    18781 aacgaactat tttggggacc atttccaatg ctaagaatga tttgattgat gatgttgctt
    18841 atgctgccca agctggcgat atgtatacgc aaattgtggc ccagtgttat acagcctatc
    18901 aaaaagaact tcgtcagtct gaatccgttg actttgatga tttgattatg ctgaccttgc
    18961 gtctctttga tcaaaatcct gatgttttga cctactacca gcaaaaattc caatacatcc
    19021 acgttgatga gtaccaagat accaaccacg ctcagtacca attggtcaaa ctcttggctt
    19081 cccgttttaa aaatatctgt gtggttgggg atgcggacca gtctatctac ggttggcgtg
    19141 gtgctgatat gcagaatatc ttggactttg aaaaggatta ccccaaagcc aaggttgttt
    19201 tgttggagga aaattaccgc tcaaccaaaa ccattctcca agcggccaac gaggttatta
    19261 aaaataataa aaatcgccgt cctaaaaatc tctggactca aaacgctgat ggggagcaaa
    19321 tcgtttacta tcgtgccgat gatgagctgg atgaggctgt atttgtagcc agaaccatcg
    19381 atgaacttag tcgcagtcaa aacttccttc ataaggattt tgcagttctc tatcggacta
    19441 atgcccagtc ccgtacaatt gaggaagccc tgctcaagtc taacattcct tataccatgg
    19501 ttggcggaac caaattctac agccgtaagg aaattcgcga tattattgct tatctcaacc
    19561 ttattgctaa tttgagtgac aatattagtt ttgagcgtat tatcaacgag cctaaacgtg
    19621 gaattggtct aggtacagtt gagaaaatcc gtgattttgc aaatttgcaa aatatgtcta
    19681 tgctggatgc ttctgctaat attatgttgt ctggtatcaa gggtaaggca gcccaatcta
    19741 tctgggattt tgccaatatg atgcttgatt tgcgggagca gctagaccac ttaagcatta
    19801 cagagttggt tgagtccgtc ctagaaaaaa caggttatgt cgatattctt aacgcccaag
    19861 cgactctaga aagcaaggca cgggttgaaa atatcgaaga gtttctttct gttacgaaga
    19921 actttgatga caccactgat gtgacagaag aggaaactgg tctggacaaa ctgagtcgtt
    19981 tcttaaatga cttggctttg attgccgaca cagattcagg tagtcaggag acatcagaag
    20041 tgaccttgat gaccctgcat gctgccaaag gtctcgaatt tccagttgtc tttttgattg
    20101 ggatggaaga aaatgtcttt ccacttagtc gtgcgactga agatccagat gaattagaag
    20161 aagagcgccg tctagcctat gtaggtatca cgcgtgcaga gaaaattctc tatctgacca
    20221 atgccaactc acgcttgctt tttggtcgta ccaattataa ccgtccgact cgttttatta
    20281 acgaaatcag ttcagacttg cttgagtatc aaggtctggc tcgtcctgca aatacaagct
    20341 ttaaggcatc atatagcagt ggtagtattt cctttggtca aggtatgagt ttggctcagg
    20401 ctcttcaaga ccgtaaacgc ggtgctgccc caaaatcaat ccagtcaagc ggtcttccat
    20461 ttggtcaatt tacagctggc gcaaaatcag catctagcga ggcaaattgg tccattggtg
    20521 acattgctct ccacaagaaa tggggagagg gaactgttct ggaagtttca ggtagcggtg
    20581 ctaggcagga attgaaaatc aatttcccag aagtaggttt gaaaaaactt ttagccagtg
    20641 tggctccaat tgagaaaaaa atctaatttt ccatccttct cacgaataat aaagtgagga
    20701 ggatttttat gtacagtatt tcattccaag aagattcact attaccaaga gaaaggctgg
    20761 ccaaggaagg agttgaagcg cttagtaacc aagagttgct agctatttta ctcaggacag
    20821 gaacacgtca agctagcgtt tttgaaattg cccaaaaagt cttgaacaat ctttcaagcc
    20881 taacggattt gaaaaaaatg accctgcagg aattgcagag tttgtctggt attgggcgtg
    20941 ttaaggccat agaattacaa gctatgattg aactggggca tcgtattcac aaacacgaga
    21001 ctcttgaaat ggaaagtatt ctcagcagtc aaaagttggc caagaagatg cagcaggaat
    21061 taggggataa aaaacaagag cacctggtgg cactctatct caatactcaa aatcaaatca
    21121 tccatcagca gaccattttt atcggttctg taactcgtag tatcgctgaa ccgcgagaga
    21181 ttctgcacta tgcaatcaag catatggcga cttctcttat cttggtccac aatcatcctt
    21241 caggagcggt agcgcctagc caaaatgatg atcatgtcac taaacttgtt aaagaagcct
    21301 gcgaattgat ggggattgtt ctcttggacc atttgattgt ctctcattct aattacttta
    21361 gttatcgtga aaagacagat ttaatctaaa gttcattaac gacatagtca aagagttttt
    21421 tatctttggg acgattttca aaaagaagtt ctggatgcca ttggacaccg agaaaggcga
    21481 catcatccgt actcatgaca gcctcaatga taccatcttt aggatcatga gccacaactt
    21541 ttaaatttgg tgctaagtcc ttgatgctct ggtggtggaa ggagttgata tgagagattt
    21601 ctccatagat ttcttggaga acggtatctg gttctgttac caagcgttga gttgtgtact
    21661 caacagaaga atcctgccaa tggtcttcga tatcttggta caaagttcca cccatggcaa
    21721 cgttaaagag ttgggtacca cggcagacag agaaaatggg ctttttctgt ttaatagctt
    21781 ccttgatgag ggtcagttcg aagatatctc tttgaaggtg atagtcatcg ctatcaatgg
    21841 ttttgggttc gccataaaat tttggatcga cattttgccc acctgtcaag atgagcttgt
    21901 caatcaaact gatatagtgg caggccattt cttgatcacc aatcggtagg atgatgggaa
    21961 tccctccaga atctttaacg ccttcaacaa agccttttgc tgcgtagctc atcatgatgt
    22021 catcatctgg atgagctttt tcgtttcctg taatcccaat aactggtttt ttcataaaat
    22081 gattttcgct ttctaatcct cttttcgcat gaagtagagg agggtttgga gttcacttgt
    22141 caaatcgaca tactgaacga ccacgtcttt tggtaaatgc agatggactg gtgaaaaact
    22201 gagaattcct ttcacaccag catcaaccaa gagattagca acctcttgtg acttgacgct
    22261 gggaacagtt aggatagcag tcttcacatc agcatccttg attttatcct tgatctgaga
    22321 aatcccgtaa atgggaatcc cgtcaggagt ttgggtaccg acttcaggat ggtcgtctag
    22381 gtcaaaggcc atgataatct tcatcttgtt acgttcgtgg aagcggtagt ggagaagggc
    22441 atggcccata tttccaatac caaccagcat gacattggta atagagttgt cattgagcaa
    22501 atcggcaaaa aatgtcatta gttttttgac atcatagcca aaaccacgac gaccaagttc
    22561 accaaaatag gaaaaatcac gacgtacggt cgctgaatca ataccgatag cctctgcaat
    22621 ttgcttagag ttggcacgtt caatcttttc tgcatgaaat ctcttaaaaa ttcgatagta
    22681 gagagagagt ctttttgctg tagcttttgg aatagcaaac tgtttatctt tcacaaaatc
    22741 acaacctttc tattcttcta ttttatagaa acattgtgaa aaaatcaaca aaaataagaa
    22801 aaaactaaga aaaatcttag ttttgatgta aaaaatctgc atgagataga aaacggtaga
    22861 ggtctccgac cagaccctga taaacttttt ggcccctaaa agtcagagaa gtcacataaa
    22921 gtgtatctgg taaggttaca catcctgaca aagtcaacat gagagcctca tgatcctcat
    22981 acttgagagt acgctctaca tgatagcagt ccttataggt cagttcaaac attttggctc
    23041 tatctttccg attttgtaaa gacaccacgt tctaccaagc tatccatgag gaagtagaat
    23101 ttttcctgat gaatatggtg gtcttctgat ttgaaaatat caactagacg aaggccaaac
    23161 ttgtcagtga tattgatttt agcccctgta agttccttgt taatgatgat tttgagttgg
    23221 aagccttcac cgctgtttgg cactttttcc aaaaggcgag tcagttcata gttaccaacc
    23281 ttagtttcaa aaaaggtgtt atctttgagg gtgaattttt taacagaagg gctaagagtg
    23341 taatcgtaac gacaattttt taactgaatg attttttcaa atgccatatg gctaacctcc
    23401 gataatttct tttaaggttt ttgcgagggt ttgtaggtct tcaacggtat tttgtggcga
    23461 caaactgatg cgaagggatt ccttcaagcg ttctgaattt gcgccataca tggcttcaag
    23521 aacatggctg gattggacaa cgcctgcagt acaggctgag ccagtagaga ttgaaattcc
    23581 agctaaatct agccgaagga gtaagaggtc atttttctga ccaggaaatc caatattgag
    23641 aacataaggg agatgatgtt ttcctctatt caagtaatac tgaatgccct ccagctctgc
    23701 cagaaaggca gtttctagat tttgtacatg ttgaaaatgt tcttcttgtt tttctaggtc
    23761 ttcttttagg gctgcaacca tgcctacgat agcaggcaga ttttcagttc ctgcacgttt
    23821 tttctgttcc tggtctccgc catgtagata ggaatcaaag tccatgctag atgcgtagag
    23881 aaaaccgatt cccttaggac catggaattt gtgggcagaa gcagtgagaa aatcaatgcc
    23941 caattcttct gaatgaattg ggattttacc aatagcctga actgcatcaa catgataggc
    24001 agcagggtgt tgcttgagta tttggccaat ttcagcgatg ggcagtaggt ttcctgtctc
    24061 attattggca aacatggtag aaaccaaaat cgtatcgtca cgtaaagcct tttgaatttg
    24121 ctgggctgtg atttcttgat tttctggctg gataatggtt gcttcaaacc caaagtgttg
    24181 aaccaagtaa tcaattgttt caaggacagc atggtgctcg atggcagttg tgatgatatg
    24241 ttttccttgt tcttggtgac gaagacagta gccaatgatg gtagtattat tgccttcagt
    24301 cccaccagaa gtgaaaaaga tatgttgagg ttttgtcctt agtaactggg ctagttcctg
    24361 acgggcttct cgcaagagtt tgccagcttg acgaccatga ccatgaatac tagaaggatt
    24421 tccgtgggtt tcttgcataa ccttggtcat agctgaaata gcaactgctg acataggagt
    24481 cgttgcagca ttgtccaaat aaatcaaaga atcaccttat ttctttttat tgtaggcaaa
    24541 gagtgggctg actggttttc tttcgtgaat acggacgata gcatcaccaa ttaactcact
    24601 agcagtgatg tagcatacat ttttaggagt tttttctttt gttgctactg aatcagtcac
    24661 aagaatttct ttaatattag tattgtcaag aagctcagca gctccctcga cgaagagacc
    24721 gtggctagaa acagcataaa tttctgtagc tccttcacgt tcaacgattt tagaagcttc
    24781 agagaaggta cgtcctgtat ttaaaatatc atcaatcaag atagctttct taccttcaac
    24841 atcaccaata atataacctt cgttacgagt tgcatcgtct tgagggtagt cgataatggc
    24901 gataggagca tcaagatatt cagccaggct acgcgcacgt ttgacacctg aatttttagg
    24961 gctaacgaca acaacatctg aaccaagcaa tcctttatcg cagtaatgtt ttgcgaatag
    25021 gggaacagtg aaaagattat ccactggaat atcaaagaaa ccttgaacct gaacggcatg
    25081 caaatcaaga gtcaggatac gatcaactcc agccttaacc agcatattgg caactagttt
    25141 tgctgtaagt ggctcacgag gacaagcaat gcggtcttga cgtgcatagc caaaatatgg
    25201 aaggacaacg ttgatactgt gggcacttgc acgcacacaa gcatcgacca tgattaacaa
    25261 ttccattagg tggttgttga cagggaaact tgttgattgg atgatgtaaa catcataacc
    25321 acggacactt tcttcgatat ttacttggat ttctccgtct gaaaattgac gtgatgatag
    25381 ttttccaagt ggggcaccaa cagcttgggc aattttttgt gcaatctctt ggttagagtt
    25441 gagtgcgaaa agtttcatgt tttttctatc tgacattata gaccgtcctc tgtaaacttt
    25501 ataaatccta gttatattta ccttacatat atgaactggg atttgtgtat ttttatcttt
    25561 tctattttac caaaaaatgg agattatttc agctattttt catacttttg acaaatcgaa
    25621 ccaattttga aggagctttt tggtaggaaa tctgattttt ctctaaaaat tgtcggaaat
    25681 cctgtttgcc ttgctcatga ttttccactt caagctccaa ttcgtaatct gttatatcaa
    25741 agtatcggct ctgatccagt gccatgagac caatagctgt tttcatttca tagcgaagcg
    25801 ttgttagaca accaagaacc tgccagttct tactttggat accatgtttc gccaattcat
    25861 ccagtactag cccttgagga agttcttcct tactcagata gttctcagca tcttttagtt
    25921 gcaatttttg gttgtattcc atgtttccaa cactctgcgg gactttgagt gtcaactcag
    25981 cccagtcttc aaaggttcga atgcgcatag cgactttctt ttctcgcagt tcaaaatcag
    26041 gcgtgtcgat gtagtaattt gtttgaagaa caggagtgac acctgtgaac tggtctttta
    26101 gacgattgta ttcatctttt ttcaatagtg ttttcaattc aatttctaaa tgtttcattt
    26161 ttcttacctt tttttatcgt tgaaagcgga tttatggtat aataagcatt gtatttattg
    26221 tatatgaatc tggagaaaaa atcaaagata tttttgacgg ataatatgag aacaagggag
    26281 aatatatgac cttagaatgg gaagaatttc tagatcctta cattcaagct gttggtgagt
    26341 taaagattaa acttcgtggt attcgtaagc aatatcgtaa gcaaaataag cattctccaa
    26401 ttgagtttgt gaccggtcga gtcaagccaa ttgagagcat caaagaaaaa atggctcgtc
    26461 gtggcattac ttatgcgacc ttggaacacg atttgcagga tattgctggc ttacgtgtga
    26521 tggttcagtt tgtagatgac gtcaaggaag tagtggatat tttgcacaag cgtcaggata
    26581 tgcgaatcat acaggagcga gattacatta ctcatagaaa agcatcaggc tatcgttcct
    26641 atcatgtggt agtagaatat acggttgata ccatcaatgg agctaagact attttggcag
    26701 aaattcaaat tcgtactttg gccatgaatt tctgggcaac gatagaacat tctctcaact
    26761 acaagtacca aggggatttc ccagatgaga ttaagaagcg actggaaatt acagctagaa
    26821 tcgcccatca gttggatgaa gaaatgggtg aaattcgtga tgatatccaa gaagcccagg
    26881 cactttttga tcctttgagt agaaaattaa atgacggtgt aggaaacagt gacgatacag
    26941 atgaagaata caggtaaacg aattgatctg atagccaata gaaaaccgca gagtcaaagg
    27001 gttttgtatg aattgcgaga tcgtttgaag agaaatcagt ttatactcaa tgataccaat
    27061 ccggatattg tcatttccat tggcggggat ggtatgctct tgtcggcctt tcataagtac
    27121 gaaaatcagc ttgacaaggt ccgctttatc ggtcttcata ctggacattt gggcttctat
    27181 acagattatc gtgattttga gttggacaag ctagtgacta atttgcagct agatactggg
    27241 gcaagggttt cttaccctgt tctgaatgtg aaggtctttc tcgaaaatgg tgaagttaag
    27301 attttcagag cactcaacga agccagcatc cgcaggtctg atcgaaccat ggtggcagat
    27361 attgtaataa atggtgttcc ctttgaacgt tttcgtggag acgggctaac agtttcgaca
    27421 ccgactggta gtactgccta taacaagtct cttggcggtg ctgttttaca ccctaccatt
    27481 gaagctttgc aattaacgga gattgccagc cttaataatc gtgtctatcg aacactgggc
    27541 tcttccatta ttgtgcctaa gaaggataag attgaactta ttccaacaag aaacgattat
    27601 catactattt cggttgacaa tagcgtttat tctttccgta atattgagcg tattgagtat
    27661 caaatcgacc atcataagat tcactttgtc gcgactccta gccataccag tttttggaac
    27721 cgtgttaagg atgcctttat cggtgaggtg gatgaatgag gtttgaattt atcgcagatg
    27781 aacatgtcaa ggttaagacc tttttaaaaa agcacgaggt ttctaaggga ttgctggcca
    27841 agattaagtt tcgaggtgga gctattctgg tcaataatca accgcaaaat gcaacgtatc
    27901 tattggacgt tggagactac gttaccattg acattcccgc tgaggaaggc tttgaaacct
    27961 tggaggctat tgagcatcta ttagatattc tctatgagga tgatcacttt ctagtcttga
    28021 ataaacccta tggagtggct tctattccta gtgtcaatca ctctaatacc attgccaatt
    28081 ttatcaaggg ttactatgtc aagcaaaatt atgaaaatca gcaggttcac attgttacca
    28141 gactagatag ggacacttct ggcttgatgc tctttgccaa gcacggttat gcccatgcac
    28201 gattagacaa gcagttgcag aagaaatcta tcgagaaacg ctactttgct ttggttaagg
    28261 gagatggaca tttggagcca gaaggggaaa ttattgctcc gattgcgcgt gatgaagatt
    28321 ccattattac cagacgagtg gctaaaggcg gaaagtatgc ccatacttca tacaagattg
    28381 tagcttctta tggaaatatt cacttggtct atattcacct gcacactggt cgaacccatc
    28441 aaatccgagt ccatttttct catatcggtt ttcctttgct gggagatgat ttgtatggtg
    28501 gtagtctgga agatggtatt caacgtcagg ctctgcattg ccattaccta tccttttatc
    28561 atccattttt agagcaagac ttgcagttag aaagtccctt gccggatgat ttcagtaacc
    28621 ttattaccca gttatcaact aatactctat aaaaactgtc tcagagtata attattatct
    28681 taaaggagaa aactcatgga agtttttgaa agtctcaaag ccaaccttgt tggtaaaaat
    28741 gctcgtatcg ttctccctga aggggaagag cctcgtattc ttcaagcaac aaaacgctta
    28801 gtaaaagaaa cagaagtgat tcctgttttg cttggaaatc ctgaaaaaat taaaatttat
    28861 cttgaaattg aaggaatcat ggatggttat gaggtcatcg accctcaaca ttatcctcaa
    28921 tttgaagaaa tggtttctgc cttggtggag cgtcgcaagg gcaaaatgac tgaagaagat
    28981 gtacgcaagg ttttggttga agatgtcaac tactttggtg tgatgttggt ttacttgggc
    29041 ttggttgatg gaatggtgtc aggagcgatt cactcaacag cttcaacagt tcgtccagct
    29101 ctacaaatca tcaaaactcg tccaaatgta actcgtactt caggagcctt cctcatggtt
    29161 cgtggtacgg aacgttacct atttggagac tgtgccatta acatcaatcc agatgcagaa
    29221 gccttggctg aaattgccat caactcagca atcacagcta agatgtttgg catcgaacct
    29281 aaaattgcca tgttgagcta ttctactaaa ggttcagggt ttggtgaaag cgttgataag
    29341 gtcgttgaag caactaaaat tgctcacgac ttgcgtcctg accttgaaat cgatggtgag
    29401 ttgcaatttg atgcagcctt tgttcctgaa actgcagctc tgaaagctcc tggaagtacg
    29461 gtagctggtc aagcaaatgt cttcatcttc ccaggtatcg aggcaggaaa tatcggttac
    29521 aagatggctg aacgcctagg tggctttgcg gctgtaggac ctgttttgca aggtttaaac
    29581 aagccagtta atgatctttc tcgtggatgt aatgcagatg atgtttacaa gttgaccctc
    29641 atcacagcag ctcaagcagt tcatcaatag tgaaaactat aaagcgatat actatgctat
    29701 actgtagtta tgaaactatg tacgaaaagc actgccatta attcctgaga actaaattac
    29761 tgattggtgt caaaaaggaa aacttccaag cgataatatc ctgtctatac acgacctata
    29821 gaaatctgta atatacatgt ccgtaaaacg ataaattccc tttttgattt taaatgagta
    29881 tgaaaagaga attttttggc tctttg
//
LOCUS       DAVKEV010000027        29851 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVKEV010000027 DAVKEV010000000
VERSION     DAVKEV010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29851
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.027"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            354..1517
                     /locus_tag="VWZ68_001283"
     CDS             354..1517
                     /locus_tag="VWZ68_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEU9372306.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFISKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            1514..2191
                     /locus_tag="VWZ68_001284"
     CDS             1514..2191
                     /locus_tag="VWZ68_001284"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEU9372307.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            2181..3035
                     /locus_tag="VWZ68_001285"
     CDS             2181..3035
                     /locus_tag="VWZ68_001285"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEU9372308.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEAHLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            3054..4121
                     /locus_tag="VWZ68_001286"
     CDS             3054..4121
                     /locus_tag="VWZ68_001286"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEU9372309.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            4131..5297
                     /gene="aroC"
                     /locus_tag="VWZ68_001287"
     CDS             4131..5297
                     /gene="aroC"
                     /locus_tag="VWZ68_001287"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEU9372310.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            5307..6410
                     /locus_tag="VWZ68_001288"
     CDS             5307..6410
                     /locus_tag="VWZ68_001288"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEU9372311.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLESIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITKNTDYTVVIK"
     gene            6421..6759
                     /locus_tag="VWZ68_001289"
     CDS             6421..6759
                     /locus_tag="VWZ68_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEU9372312.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            6851..8134
                     /gene="aroA"
                     /locus_tag="VWZ68_001290"
     CDS             6851..8134
                     /gene="aroA"
                     /locus_tag="VWZ68_001290"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEU9372313.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSASFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            8127..8603
                     /locus_tag="VWZ68_001291"
     CDS             8127..8603
                     /locus_tag="VWZ68_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEU9372314.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            8600..9448
                     /gene="pheA"
                     /locus_tag="VWZ68_001292"
     CDS             8600..9448
                     /gene="pheA"
                     /locus_tag="VWZ68_001292"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU9372315.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEGVTIPLQSQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            9445..10719
                     /gene="psr"
                     /locus_tag="VWZ68_001293"
     CDS             9445..10719
                     /gene="psr"
                     /locus_tag="VWZ68_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEU9372316.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            10998..11843
                     /locus_tag="VWZ68_001294"
     CDS             10998..11843
                     /locus_tag="VWZ68_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU9372317.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGTLR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSYKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKDPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            11833..12936
                     /locus_tag="VWZ68_001295"
     CDS             11833..12936
                     /locus_tag="VWZ68_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU9372318.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDLEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            12938..13924
                     /locus_tag="VWZ68_001296"
     CDS             12938..13924
                     /locus_tag="VWZ68_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9372319.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            13940..15376
                     /locus_tag="VWZ68_001297"
     CDS             13940..15376
                     /locus_tag="VWZ68_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEU9372320.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNNVSLLSTLLFLL
                     VSSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVM
                     VSILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRL
                     FERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSF
                     IAANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAM
                     GVLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPV
                     LDYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYI
                     MELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSE
                     SFFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            15405..16439
                     /locus_tag="VWZ68_001298"
     CDS             15405..16439
                     /locus_tag="VWZ68_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU9372321.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            16639..17376
                     /gene="mecA"
                     /locus_tag="VWZ68_001299"
     CDS             16639..17376
                     /gene="mecA"
                     /locus_tag="VWZ68_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEU9372322.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            17527..18813
                     /locus_tag="VWZ68_001300"
     CDS             17527..18813
                     /locus_tag="VWZ68_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEU9372323.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            18815..19684
                     /locus_tag="VWZ68_001301"
     CDS             18815..19684
                     /locus_tag="VWZ68_001301"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEU9372324.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAAAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            19760..19831
                     /locus_tag="VWZ68_001302"
                     /pseudo
     CDS             19760..19831
                     /locus_tag="VWZ68_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            19979..20917
                     /gene="msrB"
                     /locus_tag="VWZ68_001303"
     CDS             19979..20917
                     /gene="msrB"
                     /locus_tag="VWZ68_001303"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU9372325.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            20975..22699
                     /locus_tag="VWZ68_001304"
     CDS             20975..22699
                     /locus_tag="VWZ68_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9372326.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLSKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQKLWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFIILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            22701..24449
                     /locus_tag="VWZ68_001305"
     CDS             22701..24449
                     /locus_tag="VWZ68_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9372327.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLVIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            24841..26100
                     /locus_tag="VWZ68_001306"
     CDS             24841..26100
                     /locus_tag="VWZ68_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEU9372328.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    26176..26311
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            26350..26850
                     /locus_tag="VWZ68_001307"
     CDS             26350..26850
                     /locus_tag="VWZ68_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEU9372329.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            26926..27294
                     /gene="rplL"
                     /locus_tag="VWZ68_001308"
     CDS             26926..27294
                     /gene="rplL"
                     /locus_tag="VWZ68_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEU9372330.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            27541..>29851
                     /locus_tag="VWZ68_001309"
     CDS             27541..>29851
                     /locus_tag="VWZ68_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU9372331.1"
                     /translation="MSLRNKIEQHIKELEGGKFQKLGDAYLSRKYNFNIVSLGSQEGT
                     DKTTKGIPDSYAVENGKYVYIMYGTHKSVISKLEGDIQSVKKKILEENIAEDKVGRLI
                     CCHTSSNITIKQKEDLEKMAEPYHLELIGINEIANDLTKIDFQYLAKEYLSISESTEQ
                     VWSINDFIRIHDESKTNAPISNDYIGDVSEIINTIKSSEKRIFLISAKPGTGKTRLAI
                     EICSLLDRNKYNIICVKSNNQDIYQDVKRNLNLHKENIVFIDDVNTTQNYISTLGLLN
                     TTSNIRFILTVRDYAKKDVINNIKVYGYNNIEPELIKDDNFKELLNQFSRNDFTNQEI
                     EHIKTISKSNPRIAVIAAKLSSSQDLTNFNDEIDILKDYYEEILNKNNIIYAEQKTLF
                     ILSYLKKIRLESLEENQEFNKLLKITDITNTDFKSAVEKLHERELCNIYNDKIVKIAD
                     QSLDDYIVIKFLINKKISILEILHELYPVNDQRVVQILNQCSNFIRKESDLEGVSDAV
                     KSYYYNESNFESDELKEKFLIQFGVLLPLEAISHVKNKIDNIESQVYTKTNFINQKDK
                     KGSIEDSVLNIVFVTTRTKYCSQILQLLLKYFDKNPNKISEVYSILEANYGLVTEREY
                     IDYTLAENTISELANLDLTKSYNQELIVTILKQFLKIEIERTETHEEKFTFGRYKVPD
                     SEKLKQYHRSILKLLANLYNIGSCETRFYIEKMLYDYRRKILTYSESHRNTIFGDLRN
                     IRKLFFNDIKNLSMIGEKIVYALHKAEVKE"
BASE COUNT         9081 a         5405 c         6588 g         8777 t
ORIGIN      
        1 aaaaggcttt tctataaaat caaattttcc agatatctac tgaagctgat ttatttcttc
       61 atctttcttc tactaccttt gtcactaaat ttgacagaca catattgctg atacaacctc
      121 tctacctata atctcacggt taacctgagg ctagtttcat agtttgctat ttgattttcg
      181 ttgataaaaa gaaatgctcc tccaagacgg aagagcattt tttactgtga ttcttacaca
      241 tttacttcct agttttgcag gaagtctagt ataccatttt ttaaaagaag agtaaaaaag
      301 caagggtagt ttcttttttg agaattgtct aaaagtttga tataatggta gttatgaata
      361 gaataagagt cagcaaaagg gttgaaaaga agcttgctaa ggggctagtt ttactagaag
      421 ccagtgatct tgagaatgtc aatcttaagg atcaggaagt agaggtgcag ggtcaggaag
      481 gaaactttct tgggactgcc tacctttctc agcaaaacaa gggcttgggc tggtttatca
      541 gcaaagacaa ggtggccttc aatcaagctt tctttgaaac gttgtttaga aaagccaaag
      601 aaaagagaaa cgcctactat caagatgatt tgacaactgc ctttcgtctc tttaatcaag
      661 agggagatgg ctttgggggt ctgacagtgg acctttatgg cgactacgcc gtcttttctt
      721 ggtataactc ttatgtttat cagattcgtc agactatatc agaagccttt agacaggttt
      781 tccctgaggt tttaggagct tatgagaaaa tccgctttaa gggtttggac tatgaatctg
      841 cccatgttta tggtcaagaa gcacctgact ttttcactgt tttagaaaat ggtgtcctgt
      901 atcaagtctt tatgaatgat ggcttgatga caggaatttt cctagaccag catgaggttc
      961 gcggtagttt agttgacggc ttggctatgg gtaaatcctt gctcaatatg ttttcctaca
     1021 cagcggcttt ttcagtagct gcggccatgg gaggagctag ccagacaact tctgttgatc
     1081 tagccaaacg ttcacgagaa ttgtctcaag cgcattttca ggcaaatggg ctcagcacag
     1141 acgagcatcg ttttatagtc atggatgtct ttgagtattt caaatatgcc aaacgcaaag
     1201 acttgaccta cgatgtgatt gtcctagatc cgcctagctt tgctcggaat aaaaaacaaa
     1261 ctttctctgt ggccaaggat tatcacaagt tgatttccca gagtcttgag attttaaatc
     1321 cgggagggat tatcattgcc agtaccaatg ctgccaatgt ttcccgtcag aaatttacag
     1381 aacaaattga taaaggtttt gcaggaagaa gttaccagat tttaaacaaa tatggtcttc
     1441 cagcagattt tgcctataat aaaaaagatg aaagtagtaa ttacctcaag gtgattagta
     1501 tgaaggttag taaatgaaat taatcgtttc agtaatgcca agaagtttag aggaggctca
     1561 ggctctggat gccacgaggt acctggatgc cgacatcatt gaatggcgtg ccgactatct
     1621 gcctaaagaa gcgattttgc aggtagctcc agccattttt gaaaaattcg caggccgtga
     1681 gttggttttc acgctacgaa ctcgctccga aggtggagaa atcgaccttt ctccagaaga
     1741 gtatatccat ctaatcaagg aagttgcgca actctatcaa ccagactata ttgattttga
     1801 gtactatagc tacaaggatg tttttgagga aatgctggac ttcccaaatc ttgttttgag
     1861 ttaccataat ttccaagaaa cacctgagaa catgatggaa atcttgtcag agttgacgat
     1921 cctaaatcca aaacttgtta aggttgcggt gatggctcac acggagcagg atgtcttaga
     1981 cttgatgaac tatacacgag gctttaaaac cctcaatcct gaacaggaat atgtgaccat
     2041 ttctatgggt aaggtgggca aggtctctcg tatcactgcg gatgtgactg gttcgagttg
     2101 gtcttttgcc agtctggatg aggttagtgc ccctgggcag atttctctag ctagcatgaa
     2161 aaaaatcagg gagattttgg atgaagcttg atggctatac acgtttagct gcagttgttg
     2221 ccaatcctat taagcattct atttctccct tcatccacaa tagagccttt gaggcgacag
     2281 ctaccaacgg tgcttatgtg gcttgggaga ttgaagcgag tgacttggca gaaacagtgg
     2341 ccaatattcg tcgctaccag atgtttggca tcaatctgtc catgccctat aaggagcagg
     2401 tgattcctta tttggataag ctgagcgatg aagcgcactt gattggtgcg gttaatacgg
     2461 ttgtcaatga gaatggcaat ttaattggat ataatacaga tggcaaggga ttttttaagt
     2521 gcttgccttc ttttacaatt tcaggtaaaa agatgaccct gctgggtgca ggtggtgcgg
     2581 ctaaatcaat cttggcacag gctattttgg atggcgtcag tcagatttcg gtctttgttc
     2641 gttccgtttc tatggaaaaa acaagacctt acctagacaa gttacaggag cagacaggtt
     2701 ttaaagtgga tttgtgtgct ttagaatatg tttctgaact gcaagcaagg attgccgagt
     2761 cggatttgct agttaatgcc accagtgtgg gcatggatgg ccaatcctct cctgttcctg
     2821 aaaacatagt cttaccagaa actctcttag ttgcagatat catataccaa ccctttgaaa
     2881 caccgttttt gaaatgggct agaagtcagg gcaatccagc agtcaatggt ctgggaatgt
     2941 tgctctatca agctgcagaa gcttttcaac tgtggacagg caaggaaatg ccgacagaag
     3001 agatttggca gtctttaaca gaaaaatacc aataaagaaa gggagactct cctatgaaaa
     3061 tcagaatcga tattcctcat catccttatg atattcagat tgaaaaaggt tgtatggccc
     3121 aggctggtca gtggttgcga gaactctggc aaccgcaaaa ggtagtcatt gtgacagata
     3181 accatgtagc ctctctctat gcagagaagg tcaagctcag cctagaagat gctggttttc
     3241 aggtagctgt ttttgatttc ttagaaggtg aagaaagaaa gaatttaact actgttcaga
     3301 aagtctatga atttctagtc aagcaaggtc tgactcgtag cgatggaatc gttgctcttg
     3361 gtggtggcgt tgttggggac ctggctggat ttgtagcctc tacctatatg cggggtattc
     3421 actttgttca gattccgact agtttgacag ctcaggttga ttcttctatc ggtggaaaga
     3481 caggcgttaa cacaccattt gctaaaaata tggtggggac ctttgcccaa ccagatgggg
     3541 ttctgattga tccacttgtt cttgaaaccc tcggaaaaag agagttgatt gaagggatgg
     3601 gtgaagttat caagtatggc ttgattgagg atccagaact gtgggctctc ttgacgggac
     3661 tgaatggttc tgttgagagt attttggaac atgcagagac cttgattgaa cattcttgtc
     3721 aggtgaagcg caagatggtg gttgaagatg agttggacaa tggtattcgt ctttacctca
     3781 attttggcca cactattggc catgccatcg aagcgactgc cggttatggc aaggtcatgc
     3841 atggagaggc tgttgccatg ggaatggtac agatttccaa ggttgctgag gaaaaaggcc
     3901 tcatgccagc tggcattacc caatctatca cagagatgtg tcagaaattc ggcttgcctg
     3961 ttgactatga aaattggaaa gttgacaagc tttatcaggc tcttactcat gacaagaaag
     4021 cgcgtggtaa caccttgaaa ttggtcttgg tgccagagct tggttcagcg accattcacc
     4081 cagtttctct ggaagagatg aaagactact tggtaaaata aggagagtgt atgagatatt
     4141 taactgcagg agaatcacac ggcccccgtc taacagctat tattgaggga attccagctg
     4201 gacttccatt gacagctgag gatatcaatg aggatcttag acgccgtcag ggtggctacg
     4261 gtcgtggtgg tcgtatgaag attgagagtg accaggttgt ctttacttcg ggtgttcgcc
     4321 acgggaagac gacaggggcg cctattacta tggatgtcat caataaggac caccagaaat
     4381 ggctggacat catgtctgcg gaggacattg aagaccgcct taaaagcaag cggaaaatta
     4441 ctcatcctcg cccaggtcat gccgatttgg ttggggggat taagtaccgt tttgatgatt
     4501 tgcgaaattc tttggagcgt tcatcagctc gtgaaaccac catgcgggtg gcagttggtg
     4561 cagtagccaa acgcctcttg gctgagctgg atatggagat tgccaaccat gtcgtggtct
     4621 ttggtggtaa ggaaatagat gttcctgaaa atctgacagt cgctgaaatt aagcaaagag
     4681 ctgcccagtc tgaagtttct attgtcaacc aagaacgaga acaggaaatc aaggactata
     4741 ttgaccaaat caaacgtgat ggtgatacca tcggtggggt tgtggagaca gtcgtcggag
     4801 gagttccagt tggtcttggt tcctatgtcc aatgggatag aaaattggat gcaagattgg
     4861 ctcaagctgt tgtctctatc aatgccttta aaggggtgga atttggtctt ggctttgagg
     4921 ctggttatcg taaaggcagc caagttatgg atgaaattct ctggtctaaa gaagacggtt
     4981 atactcgccg taccaataat ctaggtggtt ttgaaggtgg tatgactaat gggcaaccca
     5041 tcgttgttcg tggggtcatg aaacccattc ctactcttta taaacctctt atgagtgtgg
     5101 atatcgaaac ccacgaacct tacaaggcaa ccgtggagag aagtgatccg actgctcttc
     5161 cagctgcagg aatggtcatg gaagcagttg tagcaacggt tctggcgcaa gagatcctcg
     5221 aaaaattctc atcagataat cttgaggaac taaaagaagc ggtagccaaa caccgagact
     5281 atacaaagaa ctattaagga gttcctatgg caaaaacaat ctatatcgca ggtcttgggt
     5341 tgattggagc ctctatggca cttggtatca aacgcgatca tccagattat gaaattttag
     5401 gttataatcg tagtcaagct tcgagagata tcgccttgaa agaaggcatg attgaccgtg
     5461 caacggatga ttttgctagt tttgctcctt tggcagatgt cattatcctc agcttgccaa
     5521 tcaaacaaac tattgctttc attaaggagt tggccaattt ggatttgcga gaaggcgtta
     5581 ttatttcaga tgctggttcg accaagtcaa ccattgtgga tgcggcggag cagtatttgg
     5641 ctggcaagtc tgttcgcttt gtcggggccc atcccatggc tggtagtcac aagacagggg
     5701 ctgcttcggc agatgtcaat ctttttgaaa atgcctatta tatctttaca ccttcaagcc
     5761 tgacaagtca ggacacgctt aaggaaatga aggatctgct ttcaggtctt catgctcgtt
     5821 ttatcgagat tgatgccaag gagcatgatc gtgtcacttc tcagattagc cattttcctc
     5881 atattttggc ttctagtctc atggagcaga ctgcggtcta tgctcaagag catgagatgg
     5941 caaggcgctt tgcggcaggt ggttttcgag atatgacccg aattgcggaa agcgagccag
     6001 gaatgtggac ctccattctc ttgtccaata gcgagaccat tctggataga attgaggatt
     6061 tcaaggaacg tttggaatcg attggtcagg ccattagtaa gggagatgaa gagcaaattt
     6121 ggaacttttt taaccaagcg cgtgaacaac gccagaccat ggaaatccat aagcgtggtg
     6181 gtgtggatag ctcttacgac ctctatgttg acgttcctga tgaagaagat gtcatcctgc
     6241 ggattttgga actgctacgt gggacttcct tggttaacat ccacatcaac gaggaaaatc
     6301 gtgaggatat tcacggaatc ctacaaattt catttaaaaa tgctcaagac ttggaaagag
     6361 ccgagcatct cataacaaaa aataccgact atacagtcgt cattaaataa ggagaagaac
     6421 atgtcaaata tttacgatag tgcaaacgaa ctcagtcgcg gtctacgcgg attaccagaa
     6481 tacaaggctg ttaaagcagc taaagatgcg attgcagcag atgctgaggc aagcaaaatc
     6541 tttacagaat atcttgcctt tcaagaggaa attcaaaaac tagcacagac aggtcaaatg
     6601 ccagatgcgt ccttccaagc taagatggaa ggctttggta aacagattca aggaaatagc
     6661 ctcttgtcag aattctttac caagcaacaa caattggcca tttacctttc tgacattgaa
     6721 aaaattgttt tcgaaccagt ttcagaattg ctgaaataag aaaagaacta tcctaaagtc
     6781 aggaattttt aaggaatttc tggcttttta tgataaaata ggtaaaagta ttgcaagtat
     6841 gaggtccagt atgaaactaa aaacaaatat tcgccattta catggtagta tccgcgtccc
     6901 aggtgacaag tctatcagcc accgttccat tatctttgga agtttggctg agggtgagac
     6961 caaggtttat gatattctgc gaggtgaaga cgttctttcg accatgcagg tttttcgtga
     7021 ccttggtgtt gaaattgagg ataaagatgg ggttattacc attcaaggtg taggcatggc
     7081 tggcttaaaa gcgccgcaaa atgcccttaa tatgggaaat tctggcacct cgattcgcct
     7141 gatttcaggt gtccttgctg gtgcagattt cgaagtagag atgtttggag atgatagtct
     7201 ttccaaacgt cctatggacc gtgtgaccct tccactgaaa aaaatgggcg tcagcatctc
     7261 agggcaaact gaacgagact tgcctcccct tcgcttaaaa gggacgaaaa acctaagacc
     7321 tattcattat gagttgccaa ttgcctctgc ccaagtcaag tcagccttga tgtttgcagc
     7381 cttacaagct aagggggagt cagttattat cgaaaaagag tgcacccgta atcatactga
     7441 agatatgttg caacaatttg gtggccattt aagtgtggat ggcaagaaaa tcacagttca
     7501 aggacctcaa aaactgactg gacaaaaggt ggtcgtacca ggagatattt ccagtgcatc
     7561 cttttggtta gtcgcaggtt tgattgtccc aaattctcgt ttagtgctgc agaatgtggg
     7621 gatcaacgaa actcgcaccg gtattattga tgtcattcgt gccatgggtg gaaaattgga
     7681 aataactgaa atcgatccag tcgctaaatc tgctaccttg attgttgagt cttctgactt
     7741 gaaaggaaca gagattggtg gcgctttgat tccacgattg attgatgaat tgcccattat
     7801 tgccctgctt gcgactcaag cccaaggtgt aacagttatc aaggatgctg aggagctcaa
     7861 ggtcaaggaa acagaccgta ttcaggttgt ggcagacgcc ttaaatagta tgggagcaga
     7921 tattactcct acggcagatg ggatgattat caaagggaaa tcagctcttc acggtgctag
     7981 agtcaatacg tttggtgacc accgtatcgg catgatgaca gctatcgcag ccctcttggt
     8041 tgcagatgga gaggtggagc ttgaccgtgc agaagccatc aataccagct atcctagttt
     8101 ctttgatgat ttggagagct tgattcatgg ctaaggtgtt attagggttt atgggggctg
     8161 gaaaatcgac tattgcaaga ggcttggacc ctaattacct tgatatggat gctctgattg
     8221 agaagcgcct aggtatgtcc attgcgaatt ttttcgctga aaagggagaa gcagcctttc
     8281 gtcaggtaga atcagaagtc ctagctgatt tactacaaac agaccaagtc gtgtcaactg
     8341 gaggaggagt ggttatttct cagagaaatc gtgacttact caagactaat acagataaca
     8401 tctacctgaa agcagatttt gaaaccctct acctacgtat cgcagctgat aaggacaatc
     8461 agcgaccgct ttttctaaat aatagcaagg aagaactagt agctattttt caagaaagac
     8521 aggcttggta tgaggaagtg gctagtcggg ttttggatgt gaccaagcta agcccagagg
     8581 aaattataga ggaactaaga tgaaaatagc ttatctaggt cccaagggat cattttcaca
     8641 ccacgttgtg cagacagctt ttcctcatga ggaattgcag gcttttgcca acattacaga
     8701 tgtcatcaag gcttatgagc aaggattagt gaactattct gtggtgccag ttgaaaattc
     8761 tattgagggt agtgttcatg aaaccttgga ctatcttttt catcaggctc acatccaagc
     8821 agtagcagaa atcgttcagc ctattcatca gcagttgatg gtggttccag gccatactaa
     8881 gattgaaaag attttttcac atccacaggc cttggctcaa ggaaagaaat tcatcgatga
     8941 acaatatcca gaggctcaaa tcgaggtaac agctagtaca gcttatgcgg cccgttttat
     9001 ttccgaacat ccagatcagc cctttgcagc agttgcacct agaagttctg ctgaagaata
     9061 tggattggaa ctgattgccg aggatattca ggaaatggaa gccaatttca cacgtttttg
     9121 ggttttggga gctgaaggtg taactattcc cttgcaatca caaactgaaa aaatgagttt
     9181 agccttgacc ctacctgaca accttccagg tgcactttat aaagccctgt cgacctttgc
     9241 ttggcgagga attgacttga caaaaattga aagtcgtcca ctcaagacag cactgggtga
     9301 atactttttc attatcgatg tggattatac cgataaggac ttggtccact ttgcccaaaa
     9361 agaattagaa gcgattggaa tccagtataa aattctgggt gcctatccta tttatccaat
     9421 atcagaccat ggaaaggaga gaagatgagt aaagaaaatc ccttaagtca tcatgagcag
     9481 ttgcgttatg attatttgct aaaaaatatt cactatctca atgagagaga aaaaaatgag
     9541 tttgcctatt tgcaagaaaa gctaactctt gctaggggaa atagtagctc tagcttggaa
     9601 caagaaagag aagagcaggt tgacttacca agctatgcga accggagtcg ctcacaatcc
     9661 aaatcacaag cactctcttt ccctccaaaa aagaaaagac ggaagctccg tcttaaacga
     9721 atttttatgg tgattttttc acttttggtc tgtgtggctt tggccatggt attcatgttt
     9781 ttgcgtggtt accaagatgc tagcgcaaag aaaactgctg atgcccgggc agctcaagta
     9841 gaagtattta atggtcagga cactagagat ggagttaata ttttaatcat gggtactgat
     9901 ggtcgaatcg gccagaacag tgttgagaca cgaactgact ctattatggt attaaatgtc
     9961 gggggctcag ataagaaaat gaagctagtc agtttcatgc gtgataattt ggtctatata
    10021 gatggttata gtcaagtgat taatggtaga aaacagacag ataacaagtt aaacgtagcc
    10081 tacgagttag gagaacaaga ggggcaaaaa ggggcagaaa tggttcgcca agtcttgaaa
    10141 gataattttg acttggacat taagtactac gccttggttg atttccaggc ctttgccaca
    10201 gcgattgaca cgcttttccc tgatggggtg acgattgatg ctcaattttc aacattgaat
    10261 gggcgtcccc taacagaagc tacagtcgga gatgatttat atgctaccga gactgagtct
    10321 ccaacccaaa ccattaaagt cggaaaacag cagatgaatg gctcgaccct gctcaattat
    10381 gctcgtttcc gtgatgatga tgaggcggat tacggccgta caaaaagaca gcaacaagtt
    10441 ttaacagcaa ttttagagca aattaaagat cccactaaac ttttcactgg ttctgaagct
    10501 cttggaaagg tttttgctat gacctcaacc aacgtaccct atactttcct cctaacaaac
    10561 ggtttatctg ttttggatgg agcaaaaaat ggtattgaaa aattgacgat tccagaactg
    10621 ggtgactggg tagatgccta tgatgtttat ggaggcttgg gcttgctggt tgatcaaaac
    10681 aaatatcaaa ccaagctcgc tcaaatgggc ttgagataag ataatactca atgaaaatta
    10741 aagtgcaaac taggaagcta gccgcaggct gctaaaaaca cagttttgag gttgtagata
    10801 agactgacga agtcagttac ctatacctac ggcaaggtga agctgacgtg gtttgaagag
    10861 attttcgaag agtataagac agaaaaatca aagtttgata gctatttgga tagcagtcag
    10921 gctttgattt tttacagtct gcaatagatt ttcacccctt gtttgtggta taatgaaacg
    10981 atacgataga aagaataatg aacaatatga ctgatttaaa agcaattcag gctcgtagtc
    11041 tggagatggc tgaatatttt gtggcctttt gtaaagaaca tgatttgctc tgttatctct
    11101 gtggcggagg cgctattggt acccttcgaa acaagggatt tattccttgg gacgacgacc
    11161 tagacttttt tatgcctcgt aaagattatg agaaattagc agaattatgg cctcgttatg
    11221 cagatgaacg ttatttcttg tcaaagagtt acaaggattt tgttgatcgt aatcttttta
    11281 ttaccattcg tgacaaggaa accacctgta tcaagcctta tcagcaggat ttggatttgc
    11341 cacatggtct ggccttggat gttttgcctt tggattatta tccgaaagat ccagctgagc
    11401 ggaaaaaaca ggttcgttgg gccttgattt attcactctt ttgtgcgcaa actattccag
    11461 aaaagcatgg tgctctcatg aaatggggaa gtcgcatttt actgggtttg actccaaaat
    11521 ctctccgtta tcgcatctgg aaaaaagctg agaaagaaat gactaagtat gatttggctg
    11581 attgtgatgg cattacagaa ttatgctcag gtcctggcta catgagaaac aagtacccaa
    11641 tcacatcttt tgaagacaat cttttcttgc catttgaagg aacagagatg cctattccaa
    11701 tcggctatga tgtctatctc agaactgctt ttggggatta tatgacgcct ccaccagcag
    11761 acaagcaggt accgcatcat gatgctgtca tcgctgatat ggataagtct tatacagaat
    11821 acaagggaga atatggtggc taagaaaaaa atcttatttt ttatgtggtc tttttctctt
    11881 ggaggtggtg cagagaagat tctatcaacc attgtttcaa atctggatct agaaaagtat
    11941 gatattgata ttcttgaaat ggagcacttt gacaagggat atgaatctgt tccaaagcat
    12001 gtacgcattt taaaatccct tcaagattat cgccaaacca gatggttacg agcttttttg
    12061 tggagaatga gaatttattt tccaagactg gctcgtcgtt tgcttgtaaa agatgattat
    12121 gatgttgaag tttcttttac cattatgaat ccaccactgt tgttctctaa aagaagagaa
    12181 gtcaagaaga tatcttggat tcatggaagt attgaagaac ttcttaagga tagctctaaa
    12241 agagaatcac atagaagcca gttggatgct gcgaatacaa ttgtagggat ttcaaaaaag
    12301 accagcaatt ctatcaagga agtttatcca gattatgctt ctaaattaca gacaatctac
    12361 aatggatatg attttcagac tattctagaa aaatctcaag agaagatcga tatcgagatt
    12421 gctcctcaaa gtatctgtac tatcggacgg attgaggaaa ataagggttc tgaccgtgta
    12481 gtggaagtga tacgattatt acaccaagag ggaaaaaact atcatctcta ttttatcggg
    12541 gctggtgata tggaagagga actgaaaaaa cgagtcaaag agtatgggat tgaggactat
    12601 gtacatttcc ttggttatca aaaaaatcct tatcagtatc tatctcagac gaaagttctc
    12661 ttgtctatgt ctaaacaaga aggttttcct ggagtgtatg tggaggcctt gagtctggga
    12721 ctccctttta tctctacgga cgttggaggg gctgaggaat tatcccaaga aggacgattt
    12781 ggacaaatca ttgagagcaa tcaagaggca gctcaggcga ttactaatta catgacttct
    12841 gcctcaaact ttgatgtcga tgaggctagc caattcattc aacaatttac aattacaaaa
    12901 caaatcgaac aagtagaaaa actattagag gagtagcatg gaaactgcat taattagtgt
    12961 gattgtgcca gtctataatg tggcgcagta cctagaaaaa tcgatagctt ccattcagaa
    13021 gcagacctat caaaatctgg aaattattct tgttgatgat ggtgcaacag atgaaagtgg
    13081 tcgcttgtgt gattcaatcg ctgaacaaga tgacagggtg tcagtgcttc ataaaaagaa
    13141 cgaaggattg tcgcaagcac gaaatgatgg gatgaagcag gctcacgggg attatctgat
    13201 ttttattgac tcagatgatt atatccatcc agaaatgatt cagagcttat atgagcaatt
    13261 agttcaagaa gatgcggatg tttcaagctg tggtgtcatg aatgtctatg ctaatgatga
    13321 aagcccacag tcagccaatc aggatgacta ttttgtctgt gattctcaaa catttctaaa
    13381 ggaatacctc ataggtgaaa aaatacctgg gacgatttgc aataagctaa tcaagagaca
    13441 gattgcaact gccctatcct ttcctaaggg gttgatttac gaagatgcct attaccattt
    13501 tgatttaatc aagttggcca agaagtatgt ggttaatact aaaccctatt attactattt
    13561 ccatagaggg gatagtatta cgaccaaacc ctatgcagag aaggatttag cctatattga
    13621 tatctaccaa aagttttata atgaagttgt gaaaaactat cctgacttga aagaggtcgc
    13681 ttttttcaga ttggcctatg cccacttctt tattctggat aagatgttgc tagatgatca
    13741 gtataaacag tttgaagcct attctcagat tcatcgtttt ttaaaaggcc atgcctttgc
    13801 tatttctagg aatccaattt tccgtaaggg gagaagaatt agtgctttgg ccctattcat
    13861 aaatatttcc ttatatcgat tcttattact gaaaaatatt gaaaaatcta aaaaattaca
    13921 ttagaacggg ggtgaccaag tgattgatgg gaaacgatta ttatttagtt tgaccatagt
    13981 cagttatgcc ttgacgctag taagtggaat tgtgtatctg tttaataata ataataatgt
    14041 tagcttactt tctactttat tgttcttgtt ggttagtagc ttaattgctt gttggaatga
    14101 tatcaagtat tacttaatcc attttatttt ctatttaacc atttttgtat ttctggtatc
    14161 aagaccgacc attgattatt ttagggatgg tgctttggat acctatcatc caatagccta
    14221 tcgttttgcc tttatagttg tcatggtttc gattctgggc ttgaccacag gaggcattct
    14281 ggctcgttac ttcatagcta ggaagaaaat aaaagtagca aatataggaa attctctaaa
    14341 agaggtttat atcaagcggt tacgctttgt atcactagga gtttttcttc taacctatcc
    14401 tttctatttc attcggttat ttgaacggct cttgtatcgt ttgcagactt cctactatgc
    14461 ctactatgca aattttgaaa gtaaactgcc ttattttacc tacattttgt ctacctttac
    14521 ggtctatgca atgtgtatgt atctggcaac caagccaaag aaattgcagg ccacagcagt
    14581 gcttgtctcc tttattgcag ctaatactat tcatttggca attgggacac gaaatccctt
    14641 tattttaagt attttatttg cttttgttta ttactttatg cgggagcaaa ctgaaaaagg
    14701 aaaatggatt gggtttaaag aaaagttagc gatttttgta ggttctccta ttctcatgtt
    14761 agcgatggga gtactcaatt atgtacggga taatgtccaa gtttctcata caggtttctg
    14821 ggatatctta cttgacttta tctataaaca agggactagt tttggtgttc tggctcgagg
    14881 ttttctattt aacagtagcc tcccttaccg agatttccgt aattttactt ttggtcctgt
    14941 tcttgattat tttgcaaggg ggagtttggg agccattttc ggaggaaaag cctttgaaca
    15001 tacaaccaat agtgtggaac tagctattga tagtaatagt tatgcccaca atctatccta
    15061 tcttgtcttg aacaaggaat acttgaaagg gcatggtatc ggaagtagtt atatcatgga
    15121 gttgtatacc gactatggta tgattggagt ctttctgctt agtttcttac tcggcgtatt
    15181 atttatagcc atgctgcaag tagcctatcg ctcaaggaca atcctatttg ctttatccct
    15241 actcatcttg aataatctat tctttatgcc aagaagcagc ttttcagaaa gtttcttcaa
    15301 tttatttaca atgcaattct ggggaattgt tcttgtgatt atatttgtag caaaaatgct
    15361 tacaaaggaa aactagtatc tactaaacaa aggagaaaaa aatcatgttt gaacattatt
    15421 cagtagctga tttgtttgca aatctttata aaaaacgaaa agcaaatatt ttagctctca
    15481 tcgctttatt tgctctcatt gctgtaccat ttacaattaa agcagttagg aataaaaaca
    15541 ctgtcaaaga tacaacaagt tattcaactt atcttatcta taaaatcact cctccagaag
    15601 attcggccaa aacgattttg aatcatcaaa ttggtggtta tagtgatttt tatgggaaat
    15661 tgattgatgg taatttgaat ggagcttatc ttttcaatga tgtagaaccc agtgagttga
    15721 aaaaaattgc cagtgaatta gacacgacgg aaacaacctt gaaaaattca acgaatgact
    15781 attggtggaa aaaattgacc gtctactata tgattgacga tgcaggggtt ggtgtgaaaa
    15841 ttttgacatc aagtaaagat gccaatgact tgttagagaa aaaaattgat gggttgattg
    15901 agaaatttaa acatgcttat gcaaatgtga aaattgaaaa actggaaacc atcaactcta
    15961 aagaattgaa cgcaaatggt gaaacagcgc ttggcttaaa tgtgaaaaat ctgattcttc
    16021 gtttagttgt tattggagtg gtttgtgtga ttttggttgt gatgggaaat gtgttagttt
    16081 atctctttaa tccaacaatc aatagagtag gtgatttttc tcagtatcaa attgattttg
    16141 taacagagat tacaacaatt gctaacctag cagatgtttt gtcatacaaa aatactggac
    16201 aggaattgac catcgttagc tcaaataaag ctatcctaga taaattgaaa cagagtcaag
    16261 aagctttaaa aggaatgcat tttgtagatt tgcaggatgt atcatctctt ttggaaagag
    16321 atacagtcct tcttgttgaa gagtacggag tgactcgtta taagaaattt gagcaaagtc
    16381 ttcaaattct cagaaactta aatcgttcta tcctcggtgt agcaaccttt aaattataag
    16441 tattctgatg tataaggtct tcaaaatcgg ctaagagccg attttgaagg ctttttctat
    16501 ctgtctgcag aaattttctc ttggagtctc ctatagaaag accctaggga aaatctatcc
    16561 gtatagagga gccttctttt gataaaatcg taaaaatcta gtataataga tagaactgaa
    16621 agtatgaggt tactagcaat gaaaatgaaa caaattagtg atacaacttt aaaaatcacg
    16681 atgtctttag aggatttgat ggatcgtgga atggagattg ctgactttct cgttcctcaa
    16741 gaaaaaacag aagagttctt ttatgctatc ttggatgagc tagagatgcc tgatagcttt
    16801 ctggatacag gcatgttgag cttccgtgtg actccaaaac ctgataaggt agatgtcttt
    16861 gtgaccaagt caaagattga ccaaaatcta gattttgaag acttatcgga tttgccagat
    16921 atggaagaat tggctcaaat gtctccagat gaatttatca aaaccctgga aaaaagcatc
    16981 gcagacaaaa ccaaggatga tatcgaagcc attcaatctc ttgagcaagt tgaagccaag
    17041 gaagaagagc aagagcaggc tgaacaagaa gctgagagta agaaagaacc ttacatctac
    17101 tacatccttt cttttgctaa gttggctgac ttggtagctt ttgccaagac agtgactttt
    17161 gaaatggaaa cttctgaact ctacaaaatg aacgagcgct attatttgac cattttagtg
    17221 gatattgaaa atcatccaag cccatatcca gcttggctgt tggcccgtat gcgcgagttt
    17281 gcagacgata gtgatatcag tcgctcagtc ttacaagagt atggtcaagt cttgatgagt
    17341 cacgatgcag tgctcaatct gcaaaaaatc ggctaatcct ttctggaaag ctattttcag
    17401 attttaagaa gagcgaatcg tctgattcgt tttttctttt tatactgaaa tagtgattta
    17461 ctataatagg aattttcaca aaattctgtt ataatggcta tattagaaaa tttcgaggag
    17521 ataaagatga cagttaaaat tgctttacta ggatttggta ccgttgcaag tggtgtgcct
    17581 ttcctcctaa aggaaaatgg aggaaaaatc aatcaatcag cacattcaga tatcaaagtt
    17641 gctaaggtat tggtcaagga tgaagatgaa aaaaatcgct tgcttgcagc agggaatgac
    17701 tttaactttg taaccaatgt ggatgatatt ttatcagacc aggatattac tatcgtagtg
    17761 gaattgatgg ggcgtattga gcctgctaaa acctttatca ctcgtgcctt ggaagctgga
    17821 aaacacgttg ttactgctaa caaggacctt ttagctgtcc atggcgcaga attgctagaa
    17881 atcgctcaag ctaacaaggt agcactttac tacgaagcag cagttgctgg tgggattcca
    17941 attcttcgta ctttagcaaa ttccttggct tctgataaaa ttacgcgcgt gcttggagta
    18001 gtcaacggaa cttccaactt catggtgacc aagatggtgg aagaaggctg gtcttacgat
    18061 gatgctcttg cggaagcaca acgtctagga tttgcagaaa gcgatccgac gaatgacgta
    18121 gatgggattg atgcagccta caagatggtt attttgagcc aatttgcctt tggcatgaag
    18181 attgcctttg atgatgtagc ccacaaggga atccgcaata tcacaccaga agacgtagct
    18241 gtagctcaag agcttggtta cgtagtgaaa ttggttggtt ctattgagga aacttcttca
    18301 ggtattgctg cagaagtgac tccaaccttc ctaccgaaag cgcacccact tgctagtgtg
    18361 aatggcgtaa tgaacgctgt ctttgtagaa tctatcggta ttggtgagtc tatgtactac
    18421 ggaccaggtg cgggtcaaaa accaactgca acaagtgttg tagctgatat tgtccgtatc
    18481 gttcgtcgtt tgaatgatgg taccattggc aaagacttca acgaatatag ccgtgacttg
    18541 gtcttggcaa atcctgaaga tgtcaaagca aactactatt tctcaatctt ggctccagac
    18601 tcaaaaggtc aggtcttgaa gttggctgaa atcttcaatg ctcaagatat ttcctttaag
    18661 caaatccttc aagatggcaa agagggtgac aaggcgcgtg tcgttatcat cacacacaag
    18721 attaataaag cccagcttga aaatgtctca gctgaattga agaaggtttc agaattcgac
    18781 ctcttgaata ccttcaaggt gctaggagaa taagatgaag attattgtac ctgcaaccag
    18841 tgccaatatc gggccaggtt ttgactcggt cggtgtagct gtaaccaagt atcttcaaat
    18901 tgaggtctgc gaagaacgag atgagtggct gattgaacac cagattggca aatggattcc
    18961 acatgatgag cgtaatctct tgctcaaaat cgctttgcaa attgtaccag acttgcaacc
    19021 aagacgcttg aaaatgacca gtgatgtccc tttggcgcgc ggtttgggtt cttccagctc
    19081 ggttatcgtt gctgggattg aactagccaa ccaactgggt caactcaact tatcagacca
    19141 tgaaaaattg cagttagcga ccaagattga agggcatcct gacaatgtgg ctccagccat
    19201 ttatggtaat ctcgttattg caagttctgt tgaagggcaa gtctctgcta tcgtagcaga
    19261 ctttccagag tgtgattttc tagcttacat tccaaactat gaattacgta ctcgcgacag
    19321 ccgtagtgtc ttgcctaaaa aattgtctta taaggaagct gctgctgcaa gttctatcgc
    19381 caatgtagcg gttgctgcct tgttggcagg agacatggtg accgctgggc aagcaatcga
    19441 gggagacctc ttccatgagc gctatcgtca ggacttggta agagaatttg cgatgattaa
    19501 gcaagtgacc aaagaaaatg gggcctatgc aacctacctt tctggtgctg ggccgacagt
    19561 tatggttctg gcttctcatg acaagatgcc aacaattaag gcagaattgg aaaagcaacc
    19621 tttcaaagga aaactgcatg acttgagagt tgatacccaa ggtgtccgtg tagaagcaaa
    19681 ataaagaata gaagatagga tggggaaact cttgaccaga gggtttcata tcctttttgt
    19741 gaaaagaagt ttatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaggctg
    19801 ctcaaaacag tgttttgagg ttgtggatag aactgaagaa gtcagctcaa gacactgttt
    19861 tgaggttgca gatagaactg acgaagtcag taacatatat acggtaaggt gacgctgacg
    19921 tggtttgaag agattttcga agagtattag ttaaaaacgt gataaaggag aaataaagat
    19981 ggcagaaatt tatctagcag gtggttgttt ttggggccta gaggaatatt tttcacgcat
    20041 ttctggagtg ctagaaacca gtgttggcta cgctaatggt caagtcgaaa cgaccaatta
    20101 ccagttgatc aaggaaacag accatgcaga aacggtccaa gtgatttacg atgagaagga
    20161 agtgtcactc agagagattt tactttatta tttccgagtt atcgatcctc tatctatcaa
    20221 tcaacaaggg aatgaccgtg gtcgccaata tcgaactggg atttattatc aggatgaagc
    20281 agatttgcca gctatctaca cagtggtaca ggagcaggaa cgcatgctgg gtcgaaagat
    20341 tgcagtagaa gtggagcaat tacgccacta cattctggct gaagactacc accaagacta
    20401 tctcaggaag aatccttcag gttactgtca tatcgatgtg accgatgctg ataagccatt
    20461 gattgatgca gcaaactatg aaaagcctag tcaagaggtg ttgaaggcca gtctatctga
    20521 agagtcttat cgtgtcacac aagaagctgc tacagaggct ccatttacca atgcctatga
    20581 ccaaaccttt gaagagggga tttatgtaga tattacgaca ggtgagccac tcttttttgc
    20641 caaggataag tttgcttcag gttgtggttg gccaagtttt agccgtccga tttccaaaga
    20701 gttgattcat tattacaagg atctgagcca tggaatggag cgaattgaag ttcgttctcg
    20761 ttcaggcagt gctcacttgg gtcatgtttt cacagatgga ccgcgggagt taggcggcct
    20821 ccgttactgt atcaattctg cttctttacg ctttgtggcc aaggatgaga tggaaaaagc
    20881 aggatatggc tatctattgc cttacttaaa caaataaaac agagagtggg gcttcccact
    20941 ttcttcattt ctagaatatg aatagaaggg atttatgaaa cacctattat cttacttcaa
    21001 accctacatc aaggaatcaa ttttagcccc cttgttcaag ctgttagaag ctgtttttga
    21061 gctcttggtt cccatggtga ttgctgggat tgttgaccaa tctttacctc agggagatca
    21121 aggtcatctc tggatgcaga ttggcctgct ccttatcttt gcagtaattg gcgttttagt
    21181 ggccttgata gctcaatttt actcagcaaa ggcagcagta ggctttgcta aggaattgac
    21241 aaacgatctt tatcgtcata ttctttcctt gtccaaggac agcagagacc gtctgacaac
    21301 ttctagtttg gtcactcgct tgacttcgga tacctaccag attcagactg gtatcaatca
    21361 attcctgcgt ctctttttgc gagcgcccat tatcgttttt ggtgccattt ttatggctta
    21421 tcgaatctca gctgagttga ctttctggtt cttagtcatg gttgccattt tgaccattgt
    21481 cattgtaggg ctatctcgat tggtcaatcc tctctacagt agtctcagaa agaaaacgga
    21541 ccaactggtt caggaaacgc gccagcaatt gcaagggatg cgggttattc gtgcttttgg
    21601 tcaagaaaaa cgagagttac agatttttca aacccttaac caagtttatg ctagattaca
    21661 agaaaagaca ggtttctggt ctagtttatt aacacctctg acctatctga ttgtcaatgg
    21721 aactcttctc gttattatct ggcaaggcta tatttcaatt caaggaggag tgctcagtca
    21781 aggtgctctc attgctctta tcaattacct cttacagatt ttggtggaat tggtcaagct
    21841 tgccatgctg atcaattccc tcaaccagtc ctatatctca gccaagagaa tcgaggaggt
    21901 ctttgcggaa tctcccgaaa acatccattc agaattagaa caaaagcaag ttaccagtgg
    21961 tcgggtttta caagtccaag aattgacttt tacctatcct gatgcggccc agccttctct
    22021 gagagacatt tcctttgata tgactcaagg acaaatcctt ggtatcattg gggggactgg
    22081 ttctggtaaa tcaagcttgg tgcaactctt acttggactt tatccagtag acaaggggaa
    22141 cattgacctt tatcaaaatg gacgtagtcc tcttaatttg gagcagtggc ggtcttggat
    22201 tgcctatgta cctcaaaagg tcgaactctt taaaggaacc attcgttcca acttgactct
    22261 aggtttcaat caagaagtat ctgaccagaa actctggcag gccttggaga ttgcgcaagc
    22321 taaggatttt gtcagtgata aggaaggact tttggatgcc ctagttgagg caggggggcg
    22381 aaatttctca ggtggacaaa aacaaaggtt gtctatcgcc cgagcagtct tgcgccaagc
    22441 tccgtttatc atcctagatg atgcaacctc ggcactggat accattacag agtccaagct
    22501 cttgaaagct attagagaaa attttccaaa cacgagctta attttgatct ctcaacgaac
    22561 ctcaacttta cagatggcgg accagattct cctcttggaa aaaggtgagt tgctagctgt
    22621 tggcaagcac gatgacttga tgaaatccag ccaagtctat cgtgaaatca atgcatccca
    22681 acatggaaag gaggactaga atgaaacgac aaactgtaaa ccagacgctc aaacgtttag
    22741 ccgtagattt agcaaaccat cccttcctcc ttttcctagc ctttctagga actattgccc
    22801 aagttggctt atcaatttac ctacctattc tgattgggca ggtcattgac caagtcctag
    22861 tggctggttc atcaccagtt ttttggcaga tttttctcca gatgctcttg gtggtaatag
    22921 gaaatactct ggtacaatgg gccaatcctc tcctctataa tcgtctaatc ttctcttata
    22981 ctagagattt gcgagagcga atcatccata agctccatcg tttaccgatt gcttttgtag
    23041 ataggcaagg tagtggagag atggttagtc gtgtaaccac ggacatcgaa cagttggcag
    23101 ctggcttgac catgattttt aaccaatttt tcattggtgt tttgatgatt ttggttagta
    23161 ttctagccat gctccaaatt catctcctca tgactctctt agtcttgctg ttgacgccac
    23221 tgtccatggt gatttcacgc tttattgcca agagatccta tcatctcttc cagaagcaaa
    23281 cagagacgag gggaattcag actcagttga ttgaagaatc gcttagccag cagactataa
    23341 tccagtcctt caatgctcaa acagaattta tccaaagatt gcgtgaggct catgacaact
    23401 actcaggcta ttctcagtca gccatctttt attcttcaac ggtcaatcct tcgactcgct
    23461 ttgtaaatgc actcatttat gcccttttag ctggagtagg agcttatcgt atcatgatgg
    23521 gttcaacctt gaccgtcggt cgtttagtga cttttttgaa ctatgttcag caatacacca
    23581 agccctttaa tgatatttct tcagtgctag ctgagttgca aagtgctctg gcttgcgtag
    23641 agcgtatcta tggagtctta gatagccctg aagtggctga aacaggtaag gaagtcttga
    23701 ccagtgacca agttaaggga gctatttcct ttaaacatgt ctcttttggc taccatcctg
    23761 aaaaaatttt gattaaggac ttgtctatcg atattccagc tggtagtaag atagccatcg
    23821 ttggtccgac aggtgctgga aaatcaactc ttatcaatct ccttatgcgt ttttatccca
    23881 ttagctcggg agatatcttg ctggatgggc aatccattta tgattataca cgagtatcat
    23941 tgagacagca gtttggtatg gtgcttcaag aaacctggct cacacaaggg accattcatg
    24001 ataatattgc ctttggcaat cctgaagcca gtcgagagca agtaattgct gctgccaaag
    24061 cagctaatgc agactttttc atccaacagt tgccacaggg atacgatacc aagttggaaa
    24121 atgctggaga atctctctct gtcggccaag ctcagctctt gaccatagcc cgagtctttc
    24181 tggttattcc aaagattctt atcttagacg aggcaacttc ttccattgat acacggacag
    24241 aagtgctggt acaggatgcc tttgcaaaac tcatgaaggg ccgcacaagc ttcatcattg
    24301 ctcaccgttt gtcaaccatt caggatgcgg atttaattct tgtcttagta gatggtgata
    24361 ttgttgaata tggtaaccat caagaactca tggatagaaa gggtaagtat taccaaatgc
    24421 aaaaagctgc ggcttttagt tctgaataag ccattctctt ttgaaagttt atggacgaaa
    24481 aaagttgcct tcgagtgact tttttgttac aatagctaga aaaattgttc actgtaatac
    24541 tcaatgaaaa tcaaagagca aactaggaag ctagccgtag gttgctcaaa gcacagcttt
    24601 gaggttgtag ataagactga cgaagtcagc tcaaaacact gttttgaggt tgcagataga
    24661 actgacgaag tcagctcaaa acactgtttt gaggttgcag atagaactga cgaagtcagc
    24721 tcaaaacact gttttgaggt tgcagataga actgacgaag tcagtaacca cacctacggc
    24781 aaagtgaatc tgaagtggtt tgaagagagt acaacttgtc ttttagaaaa ggagcctata
    24841 atgaaagtct ttcagcatgt aaatatcgtg acttgtgatc aaaatttcca tgtttatctt
    24901 gatggaatct tagcagtcaa ggattctcaa atcgtctatg tcggtcaaga taagccagcg
    24961 tttttagaac aagctgagca gattatagac tatcagggag cttggattat gcctggtttg
    25021 gtcaattgtc acacccattc tgcaatgaca ggtctgagag ggatccgaga tgacagcaat
    25081 ctccatgaat ggctcaatga ctatatctgg ccagcagaat ctgagtttac tcccgacatg
    25141 actaccaatg cggttaaaga agccctaaca gagatgctcc agtcaggaac aacaaccttt
    25201 aacgatatgt ataatcccaa tggtgtggat atccagcaaa tttatcaggt ggtgaaaact
    25261 tccaagatgc gttgttattt ttctccgact ctcttttctt cagagacaga aacaactgct
    25321 gagactataa gcagaactcg atccatcata gatgaaatct taaaatataa aaatccaaat
    25381 ttcaaggtta tggtagcacc tcattctccg tatagctgca gtagagactt gctggaagcg
    25441 agtttggaaa tggcaaaaga gctaaatatt ccgctccatg tccatgtggc ggagaccaag
    25501 gaggagtcag gaattatcct caaacgatac ggcaaacgcc cccttgcttt tcttgaagaa
    25561 ctgggttatt tagatcatcc gtccgtattt gctcacgggg tcgaattaaa cgagagagaa
    25621 attgaacgct tggcatcttc tcaagtggct atcgcccaca atcctatcag taacctcaaa
    25681 ctggcatcag gaattgctcc aattatccag ctccaaaaag cgggagtagc agtcggaatt
    25741 gcgactgact cggttgcttc caataacaat ctagatatgt ttgaggaagg aaggactgca
    25801 gctcttcttc agaagatgaa aagtggggat gccagccagt ttccaatcga aacagctctc
    25861 aaggtactga caatcgaagg ggctaaggtc cttggaatgg aaaatcagat aggaagtctg
    25921 gaagtcggca agcaagcaga ttttctggtc attcaaccac aagggaaaat tcatctccaa
    25981 cctcaggaaa atatgctgtc tcacctggtt tatgcagtta aatctagtga tgtagatgat
    26041 gtttatatcg ccggagaaca ggttgttaag caaggtcaag tcctgacagt agaactttaa
    26101 aagaaaaatt acgaaaaatt ttaaaaaaag tttgcaaaaa tcttgcattc tttttttgac
    26161 tatgctatac ttatatacgg tttaaaaaaa ctgcctaaga cagtagggga gctcgactca
    26221 taaatatcct accgaggaca aaacgtatca tgtaaaaaga agcgtattgt actttcgtgt
    26281 ctaggtttgg gcgcgttttt ctttttgaaa aattccccaa gcaaaataat tacggaggtg
    26341 aacacactaa tgagtgaagc aattattgct aaaaaagcgg aactagttga cgtagtagct
    26401 gaaaaaatga aagctgctgc atctatcgtc gttgtagacg ctcgtggttt gacagttgag
    26461 caagatacag ttcttcgtcg tgagcttcgt ggaagcgaag ttgagtataa agttattaaa
    26521 aactcaatct tgcgtcgtgc agctgaaaaa gctggtcttg aagatcttgc atctgtattt
    26581 gttggaccat ctgcagtagc attttctaat gaagatgtta tcgcaccagc gaaaatcttg
    26641 aacgactttt ctaaaaacgc tgaagcactt gaaattaaag gtggtgcaat cgaaggcgct
    26701 gtcgcatcta aagaagagat tcttgcactt gcaactcttc caaaccgcga aggacttctt
    26761 tctatgctcc tttctgtact tcaagcgcca gtgcgcaacg ttgctcttgc agtcaaagcg
    26821 gttgcagaaa gcaaagaaga cgcggcttaa tcttaagcta cacagcgtag cctagctacg
    26881 aaaaaaacta ttataaaatt taaaacttat ttggaggaaa taacaatggc attgaacatt
    26941 gaaaacatta ttgctgaaat taaagaagct tcaatccttg aattgaacga ccttgtaaaa
    27001 gctatcgaag aagaatttgg tgtaactgca gctgctcctg tagctgttgc tgcagctgat
    27061 gcagctgatg ctggtgctgc taaagattca ttcgacgttg aattgacatc tgcaggcgac
    27121 aaaaaagttg gcgttatcaa agttgtacgt gaaatcactg gtcttggtct taaagaggct
    27181 aaagaacttg ttgacggtgc accagcactt gttaaagaag gcgttgcaac tgcagaagct
    27241 gaagaaatca aagctaaatt ggaagaagct ggagcttcag ttactcttaa ataatagagc
    27301 aactacatta gtagcttaaa aacatgatta aaccgctatt cttaggagta gcggtttttc
    27361 tttttgttta aaaaggggca aactttttat atagttgttt aggaaataaa taatttttgt
    27421 ataattggtt tactactcta aattaacgta gtacaagagt ttgttaatta aactatacct
    27481 tatggttttg actagtgtga tataattatg ttgaaatact tatctggaaa ggtttttata
    27541 atgagtttaa gaaataaaat tgagcaacat attaaagagc tagagggagg gaagtttcaa
    27601 aaactaggtg acgcgtacct aagtagaaaa tacaatttta atattgtttc attaggctca
    27661 caggaaggaa cagataaaac aactaaaggg atcccagatt cttacgctgt cgaaaatggt
    27721 aaatatgttt atattatgta tggcacccat aagtctgtaa tatctaaatt agaaggagac
    27781 attcagtcag ttaagaaaaa aattttagag gaaaatattg ctgaagataa agttgggaga
    27841 cttatttgtt gtcatacttc ttcaaatata acaattaaac aaaaagaaga tctagaaaaa
    27901 atggctgagc cttatcatct agaattgatt ggaattaatg aaattgctaa tgatcttaca
    27961 aagatagatt ttcaatattt agcaaaagag tatctatcaa tcagtgaatc tacagagcaa
    28021 gtttggtcta tcaatgactt cataagaatt catgatgaga gtaaaactaa tgctcctata
    28081 tcaaatgact atattggaga tgtaagtgaa attataaata ccattaaatc aagtgaaaaa
    28141 cgaatcttct taatatctgc taagcctgga acagggaaaa ctagattagc aattgaaatt
    28201 tgctctttgc tggatcgaaa taaatataac attatttgtg tcaagagcaa taatcaggat
    28261 atttaccaag atgtaaaacg caatctaaat ttacacaaag aaaatattgt ttttattgat
    28321 gatgttaata ctacacaaaa ttatatttct acacttgggc tactgaacac gactagtaat
    28381 attcggttta ttcttacggt acgtgattat gctaaaaaag atgtaatcaa taatattaaa
    28441 gtttatgggt acaataatat tgagccagaa cttataaaag atgataattt taaggaatta
    28501 ctcaatcaat tttctcgaaa cgattttacc aatcaagaaa ttgaacatat aaaaacgata
    28561 tctaaaagca atccgcgtat tgcagtcatt gcagcaaagt tatctagctc tcaggatttg
    28621 actaatttta atgatgagat tgatatttta aaagattact atgaagaaat tttaaataaa
    28681 aacaacatta tttatgcaga acaaaagact ctatttattt tatcttactt aaaaaagatt
    28741 agactggaaa gtttagaaga gaaccaggaa ttcaataaat tactaaaaat aactgacata
    28801 acaaatactg actttaagag tgcagtggag aagcttcatg aaagagagtt gtgtaatatt
    28861 tataacgaca aaattgtaaa gatagcagat caatcattag atgattatat agttatcaag
    28921 tttttaatta acaagaaaat atcaatttta gaaattttac atgagttata tccagtaaac
    28981 gaccaaagag ttgttcaaat actaaatcaa tgttccaatt ttattaggaa agagagtgat
    29041 ttagaaggcg tttctgatgc agttaaatca tattattaca atgaaagtaa ttttgaaagt
    29101 gatgaactta aagaaaagtt tttaatacaa tttggagtat tacttccttt agaagcaatt
    29161 tcacacgtta aaaataaaat tgataatata gagtctcagg tttatacaaa gactaatttt
    29221 attaatcaga aggataaaaa gggatctatt gaggattcag ttttaaatat tgtatttgta
    29281 actacacgga caaaatattg tagtcaaatt ctccaattat tgttaaagta ctttgataaa
    29341 aatcctaata aaatttctga ggtttatagt attcttgaag caaactacgg gttggttaca
    29401 gaaagagaat atattgatta taccttagct gaaaatacca tttctgaact tgctaatctt
    29461 gatttgacga aaagttataa ccaagaatta atcgtgacaa ttttgaagca gtttcttaaa
    29521 attgaaatcg aaagaacaga gactcatgaa gagaaattta cttttgggcg ctataaagtc
    29581 ccggatagtg aaaaattaaa acagtatcat agaagtatac taaaactttt agcgaatttg
    29641 tataatatag ggagttgtga aactagattt tatattgaga aaatgctata tgattacaga
    29701 agaaaaattt tgacctattc agaaagtcat cgtaatacta tctttggaga tttgagaaat
    29761 attaggaaat tattttttaa tgacattaaa aacttatcta tgattggaga aaaaatagtt
    29821 tatgctttgc ataaagccga agtgaaagaa a
//
LOCUS       DAVKEV010000028        27699 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVKEV010000028 DAVKEV010000000
VERSION     DAVKEV010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27699
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.028"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..440
                     /locus_tag="VWZ68_001310"
     CDS             <1..440
                     /locus_tag="VWZ68_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEU9372332.1"
                     /translation="LENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAES
                     VNQALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLI
                     RRWLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     gene            662..1231
                     /locus_tag="VWZ68_001311"
     CDS             662..1231
                     /locus_tag="VWZ68_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9372333.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            1299..1949
                     /locus_tag="VWZ68_001312"
     CDS             1299..1949
                     /locus_tag="VWZ68_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEU9372334.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            1933..4173
                     /locus_tag="VWZ68_001313"
     CDS             1933..4173
                     /locus_tag="VWZ68_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEU9372335.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            4353..4541
                     /locus_tag="VWZ68_001314"
     CDS             4353..4541
                     /locus_tag="VWZ68_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372336.1"
                     /translation="MTVTKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGSY"
     gene            4573..5160
                     /locus_tag="VWZ68_001315"
     CDS             4573..5160
                     /locus_tag="VWZ68_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9372337.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMTDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            5164..6339
                     /locus_tag="VWZ68_001316"
     CDS             5164..6339
                     /locus_tag="VWZ68_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372338.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWKDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKRIF"
     misc_feature    6513..6644
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            6660..7190
                     /gene="infC"
                     /locus_tag="VWZ68_001317"
     CDS             6660..7190
                     /gene="infC"
                     /locus_tag="VWZ68_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEU9372339.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            7223..7423
                     /gene="rpmI"
                     /locus_tag="VWZ68_001318"
     CDS             7223..7423
                     /gene="rpmI"
                     /locus_tag="VWZ68_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEU9372340.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            7475..7834
                     /gene="rplT"
                     /locus_tag="VWZ68_001319"
     CDS             7475..7834
                     /gene="rplT"
                     /locus_tag="VWZ68_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEU9372341.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            7892..8272
                     /locus_tag="VWZ68_001320"
     CDS             7892..8272
                     /locus_tag="VWZ68_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9372342.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            8522..9322
                     /locus_tag="VWZ68_001321"
     CDS             8522..9322
                     /locus_tag="VWZ68_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEU9372343.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVNQRVCEDGPVFRTGTVVL"
     gene            9285..10271
                     /locus_tag="VWZ68_001322"
     CDS             9285..10271
                     /locus_tag="VWZ68_001322"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEU9372344.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            10313..12214
                     /locus_tag="VWZ68_001323"
     CDS             10313..12214
                     /locus_tag="VWZ68_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEU9372345.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     AKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWL
                     DKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIP
                     VASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINN
                     SLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYL
                     SAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMK
                     INEKLGGKD"
     gene            complement(12275..13930)
                     /gene="pavA"
                     /locus_tag="VWZ68_001324"
     CDS             complement(12275..13930)
                     /gene="pavA"
                     /locus_tag="VWZ68_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEU9372346.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            14035..14532
                     /gene="ybeY"
                     /locus_tag="VWZ68_001325"
     CDS             14035..14532
                     /gene="ybeY"
                     /locus_tag="VWZ68_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEU9372347.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLGYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            14513..14908
                     /locus_tag="VWZ68_001326"
     CDS             14513..14908
                     /locus_tag="VWZ68_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEU9372348.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            14925..15824
                     /gene="era"
                     /locus_tag="VWZ68_001327"
     CDS             14925..15824
                     /gene="era"
                     /locus_tag="VWZ68_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEU9372349.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            15873..16697
                     /gene="mutM"
                     /locus_tag="VWZ68_001328"
     CDS             15873..16697
                     /gene="mutM"
                     /locus_tag="VWZ68_001328"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEU9372350.1"
                     /translation="MPELPEVETVCRCLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQGCVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            16697..17302
                     /locus_tag="VWZ68_001329"
     CDS             16697..17302
                     /locus_tag="VWZ68_001329"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEU9372351.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFWQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            17289..18488
                     /locus_tag="VWZ68_001330"
     CDS             17289..18488
                     /locus_tag="VWZ68_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEU9372352.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            18488..18637
                     /gene="rpmG"
                     /locus_tag="VWZ68_001331"
     CDS             18488..18637
                     /gene="rpmG"
                     /locus_tag="VWZ68_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU9372353.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            18677..18910
                     /gene="secG"
                     /locus_tag="VWZ68_001332"
     CDS             18677..18910
                     /gene="secG"
                     /locus_tag="VWZ68_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEU9372354.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KVRGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            19012..21366
                     /gene="rnr"
                     /locus_tag="VWZ68_001333"
     CDS             19012..21366
                     /gene="rnr"
                     /locus_tag="VWZ68_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEU9372355.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAANYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            21329..21796
                     /gene="smpB"
                     /locus_tag="VWZ68_001334"
     CDS             21329..21796
                     /gene="smpB"
                     /locus_tag="VWZ68_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEU9372356.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            21812..22672
                     /gene="tehB"
                     /locus_tag="VWZ68_001335"
     CDS             21812..22672
                     /gene="tehB"
                     /locus_tag="VWZ68_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEU9372357.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            22745..23698
                     /gene="coiA"
                     /locus_tag="VWZ68_001336"
     CDS             22745..23698
                     /gene="coiA"
                     /locus_tag="VWZ68_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEU9372358.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            23717..25519
                     /gene="pepF"
                     /locus_tag="VWZ68_001337"
     CDS             23717..25519
                     /gene="pepF"
                     /locus_tag="VWZ68_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU9372359.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEVLKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            25521..26234
                     /locus_tag="VWZ68_001338"
     CDS             25521..26234
                     /locus_tag="VWZ68_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEU9372360.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELENFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            26301..27242
                     /gene="prsA"
                     /locus_tag="VWZ68_001339"
     CDS             26301..27242
                     /gene="prsA"
                     /locus_tag="VWZ68_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEU9372361.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFKKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(27359..>27699)
                     /locus_tag="VWZ68_001340"
     CDS             complement(27359..>27699)
                     /locus_tag="VWZ68_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU9372362.1"
                     /translation="LEQAFKEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRK
                     GNSQDNGRMESFFGILKSEMFYGYEKTFKSLNQLEQAIIDYIDYYNNKRIKVKLKGLS
                     PVQYRTKSFR"
BASE COUNT         8401 a         5067 c         6202 g         8029 t
ORIGIN      
        1 gcttggaaaa tggtcattat gaaattgata ccgtcctact gactaagata aaaaattatt
       61 gcctgttagt cttaaccgac cggcggagca gacaccaaat tataaggtta attccaaata
      121 aaactgctga atctgtcaat caggcgctta cgttactatt aggggagcat cgtattctgt
      181 ccattactgc agataatggt tcggagttca aacgattgtc tgaggtattt cctgaggaac
      241 atatctacta cgcacatgct tactcttcat gggagagagg ttcaaatgaa aatcataatc
      301 gattaattcg gagatggtta cctaaaggaa ccaagaaaac gactccgaaa gaagtagctt
      361 ttatcgaaaa ttggattaac aactacccta aaaaatgctt ggactacaag tcgccaagtg
      421 aatttctttt gggtggctaa cttcaacttg aaatttggga tttcttttgg gattccgatt
      481 aacattgaga taacctacct ttcaattgac ggtcttgttt tggttgtcac attccagttc
      541 ataaatcaaa aatgtgacgg tttcattgta tatgaaaccg cttcaaaaat caagaaaaac
      601 ttgtcatcca aattttttta tgctagacta gtgaaaatca agctctaatg gagggaaaag
      661 tatggaatca atatttgtga aatttgccca gtatccgtct atagaaacgg agcgtttatt
      721 gcttagacct gtaactttgg atgatgcgga agcaatgttt gactatgcct cggacaaggg
      781 taatacacgt tacacttttc caaccaatca aagcttggaa gaaaccaaga ataacattgc
      841 tcagttctac ttggctaatc ccttgggacg ttgggggatt gaattaaaag ataacggcaa
      901 gtttatcgga actattgact tacacaagat tgatcctgtt cttaagaagg cagctattgg
      961 ctacattatc aataaaaagt attggaatca aggattaacg acagaagcca atcgtgctgt
     1021 gattgagcta gcttttgaga agatagggat gaataagttg actgcccttc acgataaggc
     1081 taatcccgcg tcaggaaagg tcatggagaa atcaggcatg cgtttttccc atgcagaacc
     1141 atatgcttgt atggaccagc atgaaaaagg ccgaatcgtg acaagagttc attatgtctt
     1201 gaccaaggaa gactattttg caaataaata agcagttgaa aagaaatttt tcgactgttt
     1261 tttcttcctc ttacgaataa tctaagagag gagaaaatat ggaagcaatt atcgagaaaa
     1321 tcaaagagta taaaatcatc gtcatctgta ctggtctggg cttgcttgta ggaggatttt
     1381 tcctgctaaa gccagctcca caaacatctg tcaaagagac gaatttgcag gctgaagttg
     1441 cagctgtttc caaggactca tcgaccggaa aggaagtgaa caaggaagag aaggaagaac
     1501 cagttgaaca agatctaatc acagtagatg tcaaaggtgc tgtcaaatcg ccagggattt
     1561 atgacttgcc tgtaggtagt cgagtcaatg atgctgttca gaaggctggt ggcttgacag
     1621 agcaagcaga cagcaagtcg ctcaatctag ctcagaaagt tagtgatgag gctctggttt
     1681 acgttcctac taagggagaa gaagcagtta gtcaacagac tggttcgggg acagcttctt
     1741 caacaagcaa ggaaaagaag gtcaatctca acaaggccag tctggaagaa ctcaagcagg
     1801 tcaagggact gggaggaaaa cgagctcagg acattattga ccatcgtgag gcaaatggca
     1861 agttcaagtc agtagacgag ctcaagaagg tctctggcat tggtgccaag accatagaaa
     1921 aacttaaaga ctatgttaca gtggattaag aatttctcta ttcccctaat ttacctgagt
     1981 tttctgttac tatggcttta ctacgccatt ttctcagtat cctattttgc tttgttgggt
     2041 tttgtttttc tgctagtctg cctctttatc caatttcctt ggaaatcagc aggtaaagtt
     2101 ctagtgattt gtggagtctt tggcttctgg tttctgtttc aaacttggca acagagtcaa
     2161 gtgagtcaaa atttggtgga ttctgttgaa agggtacgga ttttaccaga cactattaag
     2221 gttaacggtg acagtctgtc ctttcgtggt aagtctgatg gtcgtgcttt ccaagtctat
     2281 tataaactcc agtccgagga ggagaaagaa gcctttcaag ctttaactga ccttcatgag
     2341 ataggactag aagggaagct ttcggagcca gaagggcaga gaaattttgg tggctttgac
     2401 taccaaggct atctgaagac tcagggaatt taccagacac tcaatattaa aagaatccag
     2461 tcactccaaa aggttggcag ttgggatata ggtgaaaacc tgtccagttt acgtcgaaag
     2521 gctgtggttt ggattaagat gcacttccca gaccctatgc gcaattacat gacaggactc
     2581 ttgctaggac atctggacac cgattttgag gagatgaatg agctttattc cagtttagga
     2641 attattcacc tttttgcctt gtcaggtatg caggtagggt ttttcatgga cggatttaag
     2701 aaactacttt tacgattggg cttgacacaa gaaaagttga agtggctgac ttatcccttt
     2761 tcccttatct atgcgggact aactggattt tcagcatcgg ttattcgcag tctcttgcaa
     2821 aagctactgg ctcaacatgg ggttaagggc ttggataatt ttgccttgac ggtgcttgtc
     2881 ctctttattg tcatgccaaa ctttttcttg acagcaggag gagtcttgtc ctgtgcttat
     2941 gcttttatcc tgaccatgac cagcaaagaa ggggaggggc tcaaggctgt tactagtgaa
     3001 agtctagtca tctccttggg catattgccc attctatcct tctattttgc ggaatttcaa
     3061 ccttggtcta tccttttgac ctttgtcttt tcctttcttt ttgacttggt cttcttaccg
     3121 ctcttgtcta tcttatttgt cctttccttt ctctatccag tcattcagct gaactttatc
     3181 tttgaatggt tagagggcat tattcgcttg gtctcgcagg tggcaagtag accgcttgtc
     3241 tttggacaac ccaatgaatg gcttttaatc ctattgttaa tttctttggc tttggtctat
     3301 gatttgagga aaaacattaa aaagctaacg gtattgtgct tattgattac agggctcttt
     3361 ctcctgacca agcatccact ggaaaatgaa atcaccatgc tggatgtggg gcaaggagaa
     3421 agtattttcc tacgggatgt aactgggaaa accattctca tagatgtagg tggtaaggca
     3481 gaatcttata agaaaatcaa aaaatggcaa gaaaagatga cgaccagcaa tgcccagcga
     3541 agcttgatac cctatctcaa aagtcgagga gtagctaaga ttgaccagct aattttgact
     3601 aacacggaca aggagcatgt tggagatttg tcagagatga ccaaggcttt ccatgtaggg
     3661 gagattctag tatcaaaaga cagtctgaaa cagaaggaat ttgtggcaga actacaggcg
     3721 actcaaacaa aggtgcgtag tatgatagta ggggagaact tgcccatttt tggaagtcag
     3781 ttagaagttc tatctccaag gaaaatggga gatggaggac acgatgatac cctagttctg
     3841 tatgggaaat tcttggataa gcaatttctc ttcacgggaa atttggagga gaaaggagag
     3901 aaggacttgc tgaagcacta tccagacttg aaagtaaatg ttttgaaagc tagccaacat
     3961 ggcaataaaa aatcatcaag tccagccttt ctagaaaaac tcaaaccaga gcttactctt
     4021 atctcagttg gaaagagcaa tcgaatgaaa ctcccccatc aggaaacatt gacacgactg
     4081 gaaggtatca atagcaaagt ttatcgaact gaccagcaag gagctatacg ttttaagggg
     4141 ttggatagtt ggaaaatcga aagtgttcga taggaaggat aaatgttgta gattagtgaa
     4201 ataaactaaa aatttgttgc ataataatga taaaaacggc ataatgaaaa cgtattcaat
     4261 attgaggata taaaatcatt aaaaatcagc aaaagttgtt ttagttagtt agtttataat
     4321 ctattggtct tcttcagtcc agtgtatctg ctgtgacagt cactaaaagt tacaagtatg
     4381 attggaatac ggttttggaa tatagtacca actatcacga ccatcagtat gcttggattc
     4441 cggaatggtc tcgttattac agctattctg agtataaagt tggcggaggc tggaactacg
     4501 ctcgttatga ggtcataaac tactatactg gaagttatta atccttaaag agtgagaaaa
     4561 ggagggctgg atatgttaaa tcttactcat gttaccttaa aaacgcgaca agtcatcttg
     4621 caagatgcgg attttacctt taaaaagggt aggatttatg gccttcttgc tatcaatggc
     4681 tcgggaaaga cgacactatt ccgagctatg agcaagttgc ttccccttag tagtggacac
     4741 atcgcagttc ctccttcttt gttttattat gagagcgttg aatggctgga tggaaactta
     4801 agtgggatgg actaccttcg tctcataaaa aacatctgga agtcagacct aaacttgaga
     4861 gatgaaatcg cctactggga aatgactgac tatatcagtc ttcccatccg caagtattcc
     4921 ttagggatga agcaacgctt ggtgattgct atgtattttc tcagtcaggc caaatgctgg
     4981 ctcatggatg agattacaaa tggcttagac gagtattatc gacagaagtt ttttgatagg
     5041 ctagcacaaa tcgatagaca agaacagctg gttcttttaa gttcccacta taaggaagag
     5101 ttggttgata tctgcgatag agtagtaacc attcatcagg ggcagataga agaggtttag
     5161 tttatgaaag atgttagtct atttttattg aaaaaagttt tcaaaagtcg tttaaactgg
     5221 attatcttag ctttatttgt atctgtactc ggtgttacct tttatttaaa tagtcagact
     5281 gcaaactcac acagcttgga gagcaggttg gaaagtcgca ttgcagccaa cgagagggct
     5341 atcaatgaaa atgaagagaa actctcccaa atgtctgata ccagctcgga ggaataccag
     5401 tttgctaaaa ataatttaga cgtgcaaaaa aatcttttga cgcgaaagac agaaattcta
     5461 actttactaa aagaagggcg ctggaaagaa gcctactatc tgcagtggaa agatgaagag
     5521 aagaattatg aatttgtatc aaatgacccg actgctagct ctggcttaaa aatgggggtt
     5581 gaccgcgaac ggaagattta ccaagccctg tatcccttga acataaaagc acatactttg
     5641 gagtttccga cccacgggat tgatcagatt gtctggattt tagaggttat catcccaagc
     5701 ttgtttgtgg ttgcgattat ttttatgcta acacaactat ttgcagaaag atatcaaaat
     5761 catctggaca cagctcactt atatcctgtt tcaaaagtga catttgcaat atcctctctt
     5821 ggagttggag tgggatatgt aactgtgctg tttatcggaa tctgtggctt ttcttttcta
     5881 gtgggaagtc tgataagtgg ttttggacag ttagattatc cctacccaat ttatagctta
     5941 gtgaatcaag aagtaactat tgggaaaata caagatgtat tatttcctgg cttgctctta
     6001 gctttcttag cctttatcgt cattgtggaa gttgtgtact tgattgctta ctttttcaag
     6061 caaaaaatgc ctgtcctctt tctttcactc attgggattg ttggcttatt gtttggcatc
     6121 caaacaattc agcctcttca aaggattgca catctgattc cctttactta cttgcgttca
     6181 gtggagattt tatctggaag attacctaag cagattgata atgtcgatct aaattggagc
     6241 atgggaatgg tcttacttcc ttgcctgatt atctttttgc tattgggaat tctatttatt
     6301 gaaagatggg gaagttcaca gaaaaaaaga attttttaat agattctagc tttcctatag
     6361 gtagggaaaa taagtaaaaa ctaacataga gagggaatca acttgattct ctctttttga
     6421 ttcgaaaacc aaaccaaaat acaaacacaa acttttcaaa aaataacttt ttatcttgac
     6481 aagagctaga aaacttggta tcatataaaa gttgagaaaa gcagaagtga gagcttctcg
     6541 ccttgtgaca ttaagttgcc tggccctacg gatgaaaagt ttcgaagaaa cgctatcata
     6601 acgtgcgggc ttgtatattt acgagtccgc tattgttttt ctctaataaa acaaaagagg
     6661 tgaaaaccat agcaaagcaa gacttattca tcaatgatga gattcgtgta cgtgaagttc
     6721 gcttgattgg tcttgaagga gaacagctag gcatcaagcc actcagtgaa gcgcaagctt
     6781 tggctgataa cgctaatgtt gacctagtat tgattcaacc ccaagccaaa ccgcctgttg
     6841 caaaaattat ggactacggt aagttcaaat ttgagtacca gaagaagcaa aaagaacaac
     6901 gtaaaaaaca aagcgttgtt actgtgaaag aagttcgtct aagtccaact attgacaagg
     6961 gtgactttga tacaaaactt cgtaatgcac gtaagttcct tgaaaaagga aataaagtta
     7021 aggtatctat tcgctttaag ggtcgtatga ttacccataa agagattggt gcaaaagttt
     7081 tagccgagtt tgctgaagca actcaagata ttgccatcat cgaacaacgt gctaaaatgg
     7141 atggacgtca aatgttcatg caattggcgc cagcgactga caaaaaataa ttgtcagaaa
     7201 gttaaataaa ggagaaaaaa ttatgccaaa acaaaaaaca caccgcgcat cagctaaacg
     7261 tttcaaacgt acaggttctg gtggacttaa acgtttccgt gcttacactt ctcaccgttt
     7321 ccacggaaaa actaagaaac aacgtcgtca tcttcgtaaa gcatctatgg tgcattcagg
     7381 agattacaaa cgtatcaaag caatgcttac tcgcttgaaa taatagcttg actgtaagta
     7441 aacaattcta ggaaatattt ggaggaaata aaacatggca cgtgttaaag gtggcgttgt
     7501 atcacgcaaa cgtcgtaaac gtattcttaa attagcaaaa ggttactatg gagctaaaca
     7561 catcttgttc cgtactgcaa aagaacaagt aatgaactct tactactatg cataccgtga
     7621 ccgtcgtcag aaaaaacgtg acttccgcaa attgtggatc actcgtatca atgcggcagc
     7681 tcgtatgaac ggactttcat actcacaatt gatgcatggt ttgaaattgg ctgagatcga
     7741 agttaaccgt aaaatgcttg ctgacttggc tgttaacgat gcagtagctt tcacagctct
     7801 tgcagatgca gctaaagcaa aacttggtaa ataacaactg atgagactgg aacaggattg
     7861 tccagtcttt ttaaaaataa aggagaaaaa tatggcttca aaaatgctac acacttgctt
     7921 acgagtagaa aatcttgaaa aatcaatcgc attttatcaa gatgcttttg gttttaaaga
     7981 attgcgtcgc agagattttc cagaccatgc cttcacgatt gtctatctag gtcttgaggg
     8041 tgatgactat gagttggagt tgacttataa ctacgatcac ggtccgtatg tggttggtga
     8101 tgggtttgcc catatcgccc tcagtacacc tgatcttgag gcacttcatc aagaacacag
     8161 tgcaaaaggc tatgaagtga ctgagccaaa tggtctacca ggaactacac caaactatta
     8221 ctttgtcaaa gaccctgatg gatataaggt cgaagtcatt cgtgaaaaat aatttcgtgc
     8281 aagttaagta gaatattcgt tttttacttg acttttttta gctgaaagag tatactaata
     8341 aaaattcaac ctttaagggg agtccagaga gactcacaag gtgtcagata aaagaatagt
     8401 gcaattttct agaggagact ttttgagtgt gctctcttgt gttgtacgat tttaactgag
     8461 gccttgcact agcaaggtct tttctttatc tggtcccctt aaaatttaag gaggaaaagt
     8521 tatgaatccc acatgtaaga agcgtttggg tgtcattcgg ttggaaacca tgaaggtggt
     8581 tgcacaagag gaaatcgcgc cagcaatctt tgaattagtc ctagaaggag aaatggttga
     8641 agccatgcga gcaggccaat ttcttcatct gcgtgtacca gacgatgccc atcttttacg
     8701 tcgtcctatt tcaatttcgt ctattgacaa ggcaaacaag cagtgtcacc tcatttatcg
     8761 gattgaggga gctgggactg caattttttc aaccttaagt cagggagaca ctcttgatgt
     8821 gatggggcct cagggaaatg gttttgactt gtctgacctt gatgagcaga atcaggttct
     8881 ccttgttggt ggtgggattg gtgttccacc cttgcttgag gtggccaagg aattgcatga
     8941 acgtggagtg aaagtagtga cagtcctcgg ttttgctaat aaggatgctg ttattttgaa
     9001 aacggaattg gctcagtatg gtcaggtctt tgtaacgaca gatgatggtt cttatggcat
     9061 caagggaaat gtttccgttg ttatcaatga tttagatagt cagtttgatg ctgtttactc
     9121 gtgtggggct ccaggaatga tgaagtatat caatcaaacc tttgatgatc acccaagagc
     9181 ctatttatct ctggaatctc gtatggcttg tgggatggga gcttgctatg cctgtgttct
     9241 aaaagtacca gaaagcgaga cggtcaacca acgcgtctgt gaagatggtc ctgttttccg
     9301 cacaggaaca gttgtattat aaggagaaaa ttatgactac aaatcgatta caagtgtctc
     9361 tacctggttt ggatttgaaa aatccgatta ttccagcatc aggttgtttt ggctttggac
     9421 aagagtatgc caagtactat gatttaaacc ttttaggttc tattatgatc aaggcgacaa
     9481 cccttgaacc acgttttggg aacccaactc caagagtagc agagacgcct gctggtatgc
     9541 tcaatgcaat tggcttgcaa aatcctggtt tagaggttgt tttggctgaa aagctacctt
     9601 ggctggaaag agaatatcca aatcttccta ttattgccaa tgtagctggt ttttcaaaac
     9661 aagagtatgc agctgtttct catgggattt ccaaggcaac taatgtaaaa gctatcgagc
     9721 tcaatatttc ttgtcccaat gttgaccact gtaatcatgg acttttgatt ggtcaagatc
     9781 cagatttggc ttatgatgtg gtgaaagcag ctgtggaagc ctcagaagtg ccagtttatg
     9841 tcaaattaac cccgagtgtg accgatatcg ttactgtcgc aaaagctgca gaagatgcgg
     9901 gagcaagtgg cttgaccatg atcaatactc tggttggaat gcgctttgac ctcaaaacca
     9961 gaaaaccaat cttggccaat ggaacaggtg gaatgtcagg tccagcagtc tttccagtag
    10021 ccctcaaact catccgccaa gtagcccaaa caacagacct gcctatcatt ggaatggggg
    10081 gagtggattc ggctgaagct gccctagaaa tgtatctggc tggggcatct gctatcggag
    10141 ttggaacagc taactttacc aatccttatg cctgccctga catcatcgaa aatttaccaa
    10201 aagtcatgga taaatacggt attagcagtc tggaagaact ccgtcaggaa gtaaaagagt
    10261 ctctgaggta aactgcaatc aatctgttct tgatttttta ttagtttgta atatgaattt
    10321 aggagaattt tggtacaata aaataaataa gaacagagga agaaggttaa tgaagaaagt
    10381 aagatttatt tttttagctc tgctattttt cttagctagt ccagagggtg caatggctag
    10441 tgatggtact tggcaaggaa aacagtatct gaaagaagat ggcagtcaag cagcgaatga
    10501 gtgggttttt gatactcatt atcaatcttg gttctatata aaagcagatg ctaactatgc
    10561 tgaaaatgaa tggctaaagc aaggtgacga ctatttttac ctcaaatctg gtggctatat
    10621 ggccaaatca gaatgggtag aagacaaggg agccttttat tatcttgacc aagatggaaa
    10681 gatgaaaaga aatgcttggg taggaacttc ctatgttggt gcaacaggtg ccaaagtaat
    10741 agaagactgg gtctatgatt ctcaatacga tgcttggttt tatatcaaag cagatggaca
    10801 gcacgcagag aaagaatggc tccaaattaa agggaaggac tattatttca aatccggtgg
    10861 ttatctacta acaagtcagt ggattaatca agcttatgtg aatgctagtg gtgccaaagt
    10921 acagcaaggt tggctttttg acaaacaata ccaatcttgg ttttacataa aagaaaatgg
    10981 aaactatgct gataaagaat ggattttcga gaatggtcac tattattatc taaaatctgg
    11041 tggctacatg gcagccaatg aatggatttg ggataaggaa tcttggtttt atctcaaatt
    11101 tgatgggaaa atagctgaaa aagaatgggt ctacgattct catagtcaag cctggtacta
    11161 cttcaaatcc ggtggttaca tgacagccaa tgaatggatt tgggataagg aatcttggtt
    11221 ttacctcaag tctgatggca aaatggctga aaaagaatgg gtctacgatt ctcatagtca
    11281 agcctggtac tacttcaaat ctggtggtta catggcgaaa aatgagacag tagatggtta
    11341 tcagcttgga agcgatggta aatggcttgg aggaaaagct acaaatgaaa atgctgctta
    11401 ctatcaagta gtgcctgtta cagccaatgt ttatgattca gatggtgaaa agctttccta
    11461 tatatcgcaa ggtagtgtcg tatggctaga taaggataga aaaagtgatg acaagcgctt
    11521 ggctattact atttctggtt tgtcaggcta tatgaaaaca gaagatttac aagcgctaga
    11581 tgctagtaag gactttatcc cttattatga gagtgatggc caccgttttt atcactatgt
    11641 ggctcagaat gctagtatcc cagtagcttc tcatctttct gatatggaag taggcaagaa
    11701 atattattcg gcagatggcc tgcattttga tggttttaag cttgagaatc ccttcctttt
    11761 caaagattta acagaggcta caaactacag tgctgaagaa ttggataagg tatttagttt
    11821 gctaaacatt aacaatagcc ttttggagaa caagggcgct acttttaagg aagccgaaga
    11881 acattaccat atcaatgctc tttatctcct tgcccatagt gccctagaaa gtaactgggg
    11941 aagaagtaaa attgccaaag ataagaataa tttctttggc attacagcct atgatacgac
    12001 cccttacctt tctgctaaga catttgatga tgtggataag ggaattttag gtgcaaccaa
    12061 gtggattaag gaaaattata tcgatagggg aagaactttc cttggaaaca aggcttctgg
    12121 tatgaatgtg gaatatgctt cagaccctta ttggggcgaa aaaattgcta gtgtgatgat
    12181 gaaaatcaat gagaagctag gtggcaaaga ttagtactat aagtgaatat gatttgagtg
    12241 aatagtaagt taaaaatcct gatttcaagt aaaatcagga ttttttcatg gatgcaattt
    12301 ttttggagtc tggtgtgacg cggagggtct tttgtcctgt gtaagtgaca aagccgggtt
    12361 ttccaccagt tggtttattg agttttttga cttcaatcat atctacctgc accagattcg
    12421 acaggcgccc ttgagagaag taggcagcta actctgctgc gtctgtcttg actgcatcag
    12481 atgggtcaag atttcctgag atgacaacat ggcttccagg aatgtcctta gcatggaacc
    12541 aaagttcctc cttgcgggcc attttaaagg tcaattcctc attttgaaga ttgtttcgtc
    12601 cgacatagat gatggttttg ccatcgcttg ctagatattg ttctagtttt ttgcgtttct
    12661 ggattttctc ccgttgtctt ctgcggataa aacctgtttg aatcaattct tcacggattt
    12721 cagcgatttc ttccagtcca gcttggttga ggacggtttc tacactttcc agatagagaa
    12781 tagtggcttt ggtttcttca atcaaatcag tcaagtattt gacagcttct ttgagtttct
    12841 gataccgttt aaaatagcgt tgggcattct ggttgggagt cagagcctta tcaagcgcaa
    12901 tcatgatagg ttggttggta tagtagttgt ctaggataac ctggtcttgg tcgttaggca
    12961 cttggtggag gaaggttgtc agcaattctc ctttttgacg aaattcttca gcgttgtctg
    13021 tcgccagtaa ctctttttcc tgttttttga gtttgtgtcg gtttttctga agttcatttt
    13081 caacacgacg aatcagttca ctggcctgct gtttgacgcg gtcgcgctca gccttatcct
    13141 tatagtaggt gtccaacaaa tcagaaagat ttgcaagagg ctctcccacc tgatttgcaa
    13201 aaggaactgg actgaaggaa gtctcagtca agcatggctt ggtttcttga ttgaaaaaat
    13261 ttcggaaagc ggaaagtttt tcactaacca gtatcctttc caattcattt gccgtatcgc
    13321 gtcccagacc ttgaaagagg ctttgaagat tttttgctgt tagttcttgg gtttgcagga
    13381 tttcaaagag cttttcatcc ttgatagtaa aaggattgag agattttgta cttggcggag
    13441 cgatataggt cgatcctgga agtaaggtgc ggtagctatt ttgtgaaaag ccgacgtgtt
    13501 tgataacttc gaggatttta tgactgcttt tatcgaccag tagaatatta ctgtgtttcc
    13561 ccataatttc gataatcaag gtagcctgga tatggtctcc aatctcgttt ttattggaaa
    13621 ctgtaatttc cacaatacgg tcattttcca cttgctcaat cgactcaatc agggccccct
    13681 gcaaatactt tctcaaaacc atgataaagg tagaaggttg ggctggattt tcaaaagtcg
    13741 tttgggtcag ctgaatgcgt ccaaaaactg gatgggcaga aaggagcagg cgatggcttt
    13801 ggcgattgct gcggatttgc aagaccaact cttgttcaaa aggctgattg attttctgga
    13861 tgcgaccatt cactaattcg cttcgcaatt cctcaactat gtggtgtaaa aaaaatccgt
    13921 caaatgacat cgttctctcc ttgtgattgt attccatagt attatatcaa aaaggtagaa
    13981 taaaatcatg gaaatgtggt ataataaagc caagtaaaga gaaacgagaa gcacatgtat
    14041 attgaaatgg tagatgaaac tggtcaagtt tcaaaagaaa tgttgcaaca aacccaagaa
    14101 attttggaat ttgcagccca aaaattagga aaagaagaca aggagatggc agtcactttt
    14161 gtgaccaatg agcgtagtca tgaacttaat ctggggtacc gtgacaccga ccgtccgaca
    14221 gatgtcatca gccttgagta taaaccagaa ttggaaattg cctttgacga agaggatttg
    14281 cttgaaaatc cagaattggc agagatgatg tctgagtttg atgcctatat tggggaattg
    14341 ttcatctcta tcgataaggc tcatgagcag gccgaagaat atggtcacag ctttgagcgt
    14401 gagatgggct tcttggcagt acacggcttt ttacatatta acggctatga tcactatact
    14461 ccggaagaag aagcggagat gttcggttta caagaagaaa ttttgacagc ctatggactc
    14521 acaagacaat aaacgaaaat ggaaaaatcg tgacctgata tccagtttag aatttgccat
    14581 cacagggatt tttactgcta tcaaggaaga acgcaatatg cgaaaacatg cagtgacggc
    14641 tctagtggtc atccttgcag gttttggttt tcaggtgtca cgaatcgaat ggctctttct
    14701 cctattgagc attttcttgg tggtagcctt tgaaattatc aattctgcta tcgaaaatgt
    14761 ggtggatttg gccagtcact atcacttttc catgctggct aaaaatgcca aggatatggc
    14821 ggctggcgcg gtattagtgg tttctctttt tgcagcctta acaggcgcat tgatttttct
    14881 cccacgaatc tgggatttat tattttaaac agtaagagga aattatgact tttaaatcag
    14941 gctttgtagc cattttagga cgtcccaatg ttgggaagtc aaccttttta aatcacgtta
    15001 tggggcaaaa gattgccatc atgagtgaca aggcgcagac aacgcgcaat aaaatcatgg
    15061 gaatttacac gactgataag gagcaaattg tctttatcga cacaccaggg attcacaaac
    15121 ctaaaacagc tctcggagat ttcatggttg agtctgccta cagtaccctt cgcgaagtgg
    15181 acactgttct tttcatggtg cctgctgatg aagcgcgtgg taagggggac gatatgatta
    15241 tcgagcgtct caaggctgcc aaggttcctg tgattttggt ggtgaataaa atcgataagg
    15301 tccatccaga ccagctcttg tctcagattg atgacttccg taatcaaatg gactttaagg
    15361 aaattgttcc aatctcagcc cttcagggaa ataacgtgtc tcgtctagtg gatattttga
    15421 gtgaaaatct ggatgaaggt tttcaatatt tcccgtctga tcaaatcaca gaccatccag
    15481 aacgtttctt agtttcagaa atggttcgcg agaaagtctt gcacctaact cgtgaagaga
    15541 ttccgcattc tgtagcagta gttgttgact ctatgaaacg agacgaagag acagacaagg
    15601 ttcacatccg tgcaaccatc atggtcgagc gcgatagcca aaaagggatt atcatcggta
    15661 aaggtggcgc tatgcttaag aaaatcggta gcatggcccg tcgtgatatc gaactcatgc
    15721 taggagacaa ggtcttccta gaaacctggg tcaaggtcaa gaaaaactgg cgcgataaaa
    15781 agctagattt ggctgacttt ggctataatg aaagagaata ctaagtagag gtgggctcat
    15841 gcctgcttct tgtttttaca gaaggaggac ttatgcctga attacctgag gttgaaaccg
    15901 tttgtcgttg cttagaaaaa ttgattatag gaaagaagat ttcgagtata gaaattcgct
    15961 accccaagat gattaagacg gatttggaag agtttcaaag ggaattgcct agtcagatta
    16021 tcgagtcaat gggacgtcgt ggaaaatatt tgctttttta tctgacagac aaggttttga
    16081 tttcccattt gcggatggag ggcaagtatt tttactatcc agaccaagga cctgaacgca
    16141 agcatgccca tgttttcttt cattttgaag atggtggcac gcttgtttat gaggatgttc
    16201 gcaagtttgg aaccatggaa ctcttggtgc ctgacctttt agacgcctac tttatttcta
    16261 aaaaattagg tcctgaacca agcgaacaag actttgattt acaggtcttt caatctgccc
    16321 ttgccaagtc caaaaagcct atcaaatccc atctcctaga ccagaccttg gtagctggac
    16381 ttggcaatat ctatgtggat gaggttctct ggcgagctca ggttcatcca gctagatctt
    16441 cccagacttt gacagcagaa gaagcgacag ctattcatga ccaaaccatt gctgttttga
    16501 gccaggctgt tgaaaaaggc ggttccacca ttcggaccta taccaatgcc tttggggaag
    16561 atggaagcat gcaggatttt catcaggtct atgataagac tggtcaagga tgtgtacgct
    16621 gtggtaccat cattgagaaa attcaactag gtggacgtgg aacccacttt tgtccaaact
    16681 gtcaaaggag ggactgatgg gaaaaatcat cggaatcact gggggaattg cctctggtaa
    16741 gtcaactgtg acaaattttc taagacagca aggctttcaa gtagtggatg ccgacgcagt
    16801 cgtccaccaa ctacagaaac ctggtggtcg tctgtttgag gctctagtac agcacttttg
    16861 gcaagaaatc attcttgaaa acggagaact caatcgccct ctcctagcta gtctcatctt
    16921 ttcaaatcct gatgaacgag aatggtctaa gcaaattcaa ggggagatta tccgtgagga
    16981 actggctact ttgagagaac agttggctca gacagaagag attttcttca tggatattcc
    17041 cctacttttt gagcaggact acagcgattg gtttgctgag acttggttgg tctatgtgga
    17101 ccgagatgcc caagtagaac gcttaatgaa aagggaccag ttgtccaaag atgaagctga
    17161 gtctcgtctg gcagcccagt ggcctttaga aaaaaagaaa gatttggcca gccaggttct
    17221 tgataataat ggcaatcaga accagcttct taatcaagtg catatccttc ttgagggagg
    17281 taggcaagat gacagagatt aactggaagg ataatctgcg cattgcctgg tttggtaatt
    17341 ttctgacagg agccagtatt tctttggttg taccttttat gcccatcttc gtggaaaatc
    17401 taggtgtagg gagtgagcaa gtcgcttttt atgcaggctt agcaatttct gtctctgcta
    17461 tttccgcggc gctcttttct cctatttggg gtattcttgc tgacaaatac ggccgaaaac
    17521 ccatgatgat tcgggcaggt cttgctatga ctatcactat gggaggcttg gcctttgtcc
    17581 caaatatcta ttggttaatc tttcttcgtt tactaaacgg tgtatttgca ggttttgttc
    17641 ctaatgcaac ggcactgata gccagtcagg ttccaaagga gaaatcaggc tctgccttag
    17701 gtactttgtc tacaggcgta gttgcaggta ctctaactgg tccctttatt ggtggcttta
    17761 tcgcagaatt atttggcatt cgtacagttt tcttactggt tggtagtttt ctatttttag
    17821 ctgctatttt gactatttgc tttatcaagg aagattttca accagtagcc aaggaaaagg
    17881 ctattccaac aaaggaatta tttacctcgg ttaaatatcc ctatcttttg ctcaatctct
    17941 ttttaaccag ttttgtcatc caattttcag ctcaatcgat tggccctatt ttggctcttt
    18001 atgtacgcga tttagggcag acagagaatc ttctttttgt ctctggtttg attgtgtcca
    18061 gtatgggctt ttccagcatg atgagtgcag gagtcatggg caagctaggt gacaaggtgg
    18121 gcaatcatcg tctcttggtt gtcgcccagt tttattcagt catcatctat ctcctctgtg
    18181 ccaatgcctc tagccccctt caactaggac tctatcgttt cctctttgga ttgggaaccg
    18241 gtgccttgat tcccggggtt aatgccctac tcagcaaaat gactcccaaa gccggcattt
    18301 cgagggtctt tgccttcaat caggtattct tttatctggg aggtgttgtt ggtcccatgg
    18361 caggttctgc agtagcaggt caatttggct accatgctgt cttttatgcg acgagccttt
    18421 gtgttgcctt tagttgtctc tttaacctga ttcaatttcg aacattatta aaagtaaagg
    18481 aaatctagtg cgagtaaaaa ttaatctcaa atgctcctct tgtggcagta tcaattacct
    18541 aaccagtaaa aattcaaaaa cccatccaga caagattgag gttttaaagt attgtcccaa
    18601 ggaaagaaaa gtaaccctac atcttgaatc taagtagatt ttatggtaaa ataataggga
    18661 ttttaaggag tttgatatgt ataacctatt attaaccatt ttattagtat tatctgttgt
    18721 gattgtgatt gcaattttca tgcaaccaac caaaaaccaa tccagcaatg tatttgatgc
    18781 cagttcaggt gatttgtttg aacgtagtaa agttcgcggt tttgaagctg taatgcagcg
    18841 tttgacaggg attttagtct ttttctggct agccattgcc ttagcattga cggtattatc
    18901 aagtagataa gaaaataatg ggcaggacta ggtctttgcc tctttttatt tttaaaggat
    18961 gtttgagaag gttttacagt aaaagaaaat taaaaaatct agaaagaaaa tatgaaagat
    19021 agaataaaag aatatttaca agacaaggga aaggtgactg ttaatgattt ggctcaggct
    19081 ttgggaaaag acagttccaa ggattttcgt gagttgatta aaaccttgtc cttaatggaa
    19141 agaaagcacc aaattcgttt tgaagaagat ggtagtctga cattagaaat taagaaaaaa
    19201 catgagatta ccctcaaggg gatttttcat gcccataaaa atggctttgg ctttgttagt
    19261 ctggaaggcg aggaggacga cctttttgta gggaaaaatg atgtcaacta tgctattgat
    19321 ggtgataccg tcgaggtagt gattaagaaa gtcgctgacc gcaataaggg aacagcagca
    19381 gaagccaaaa ttattgatat cctagaacac agtttgacaa cagttgtcgg gcaaatcgtt
    19441 ctggatcagg aaaaacctaa gtatgctggc tatattcgtt caaaaaatca gaaaatcagt
    19501 caaccgattt atgttaagaa accagcccta aaattagaag gaacagaagt tctcaaagtc
    19561 tttatcgata aatacccaag caagaaacat gatttctttg tcgcgagtgt tctcgatgta
    19621 gtgggacact caacggatgt cggaattgat gttcttgagg tcttggaatc aatggacatt
    19681 gtatccgagt ttccagaagc tgttgttaag gaagcagaaa gtgtgcctga tgctccgtct
    19741 caaaaggata tggaaggtcg tctggatcta agagatgaaa ttacctttac cattgacggt
    19801 gcggatgcca aggacttgga cgatgcagtg catatcaagg ctctgaaaaa tggcaatctg
    19861 gagcttgggg ttcacatcgc agatgtttct tattatgtga ccgaggggtc tgcccttgac
    19921 aaggaagccc ttaaccgtgc gacttctgtt tacgtgacag accgagtggt gccaatgctt
    19981 ccagaacgac tatcaaatgg catctgctct ctcaatcccc aagttgaccg cctgacccag
    20041 tctgctatta tggagattga taaacatggt cgtgtggtca actataccat tacacaaaca
    20101 gttatcaaga ccagttttcg tatgacctat agcgatgtca atgatatcct agctggcgat
    20161 gaagaaaaga gaaaagaata tcataaaatt gtatcaagta tcgaactcat ggccaagctt
    20221 catgaaactt tagaaaacat gcgtgtgaaa cgtggagctc tcaattttga taccaatgaa
    20281 gcgaagattt tagtggataa acaaggtaag cctgttgata tcgttcttcg gcagcgtggt
    20341 attgccgagc ggatgattga gtcttttatg ttgatggcta atgaaacagt tgccgaacat
    20401 ttcagcaagt tggatttgcc ttttatctat cgaattcacg aggagcctaa ggctgaaaag
    20461 gttcagaagt ttattgatta tgcttcgagt tttggcttgc gcatttatgg aactgccagt
    20521 gagattagtc aggaggcact tcaagacatc atgcgtgctg ttgagggaga accttatgca
    20581 gatgtattgt ccatgatgct tcttcgctct atgcagcagg ctcgttattc ggagcacaat
    20641 cacggccact atggactagc tgctaactat tatactcact ttaccagtcc aattcgtcgt
    20701 tatccagacc ttcttgttca ccgtatgatt cgggattacg gccgttctaa ggaaatagca
    20761 gagcattttg aacaagtgat tccagagatt gcgacccagt cttccaaccg tgaacgtcgt
    20821 gccatagaag ctgagcgtga agtcgaagcc atgaaaaagg ctgagtatat ggaagaatac
    20881 gtgggtgaag agtatgatgc agttgtatca agtattgtca aattcggtct ctttgtcgaa
    20941 ttgccaaaca cagttgaagg cttgattcac atcactaatc tacctgaatt ttatcatttc
    21001 aatgagcgtg atttgactct tcgtggagaa aaatcaggta tcactttccg agtgggtcag
    21061 cagatccgta tccgtgttga aagagcggat aaaatgactg gagagattga tttttcattc
    21121 gtacctagtg agtttgatgt gattgaaaaa ggcttgaaac agtctagtca tagtggcaga
    21181 gggcgtggtt caaatcgtcg ttcggataag aaggaagaca agagaaaatc aggacgctca
    21241 aatgataagc gtaagcattc acaaaaagac aagaagaaaa aaggaaagaa acctttttac
    21301 aaggaagtag ctaagaaagg agccaagcat ggcaaagggc gagggaaagg tcgtcgcaca
    21361 aaataaaaag gcacgccacg actatacaat cgtagatacg ctagaggcag ggatggtcct
    21421 gactggaact gaaatcaaga gtgtacgagc tgctcgaatt aatctcaagg atggctttgc
    21481 tcaagtgaaa aatggagaag tttggctgag caatgttcat atcgcgcctt acgaagaggg
    21541 caatatctgg aaccaggaac cagaacgtcg tcgtaaactc ctgctccata aaaagcaaat
    21601 tcaaaaattg gaacaagaga ccaaagggac aggaatgacc ttagttcccc ttaaggtcta
    21661 tataaaagat ggctacgcta agcttctttt aggacttgcc aaagggaagc atgactatga
    21721 caaacgggag tctatcaaac gtcgtgagca aaatcgagat atcgcgcgtg tgatgaaagc
    21781 tgttaatcag cgataaaaag aggaattgaa aatggaaaaa ttagttgcct ataaacgcat
    21841 gcctttgtgg aataaacaaa caatgcctga agctgttcag caaaagcaca atacaaaagt
    21901 tgggacttgg gggaaaatta ctgtcttgaa gggagctctc aagtttattg aattgacaga
    21961 agaaggggaa gttctagctg aacacctctt tgaagcaggg gcagacaatc caatggccca
    22021 acctcaagcc tggcaccgag tggaagctgc cacagatgat gtggaatggt acttggaatt
    22081 ttattgtaaa cctgaggatt attttgctaa aaaatacaat accaatcctg ttcattcaga
    22141 ggtcctagag gccatgcaga cagtgaaaca agggaaagct ttggatttgg gttgtggtca
    22201 ggggcgtaat tctctttttc tagcccagca agattttgat gtgacggctg tagatcaaaa
    22261 tggactagct cttgaaatct tgcaaagcat tgtggagcag gaagatttgg acatgcctgt
    22321 tggcctttac gatatcaatt cagctagcat tgaacaagaa tatgatttta tcgtttcaac
    22381 agttgttctc atgtttctac aagcggaccg cattccagct attattcaaa atatgcagga
    22441 gaaaaccagt gttggtggtt acaaccttat cgtttgtgcc atggacacgg aggattatcc
    22501 ttgctcggtt aatttcccat tcacctttaa agaaggagaa ctggcagact attacaagga
    22561 ttgggaattg gttaagtaca atgaaaatcc aggccatttg caccgtcgcg atgagaatgg
    22621 caatcgtatt caactacgct ttgcgacctt actagctaag aaaatcaagt aaacacacat
    22681 gaagattagg aattttcctg atcttttttc ttttttacga atgatataga aaaggaggga
    22741 attcatgttt gttgcgagag atgctagggg agaattggta aatgtgttag aggataaact
    22801 tgagaagcaa gcatacacct gcccagcttg tggaggccag ctccatttgc gtcaaggacc
    22861 aagtgtacgg acgcattttg cccataaatc cttaaaagac tgtgattttt tctttgaaaa
    22921 tgaaagtcca gaacacctgg ccaataagga atccctctat cactggttga aaaaagagac
    22981 aaaggttcaa ttagagtacc cgctttcaga acttaaacag attgcggatg tatttgtaaa
    23041 tggcaatcta gctctagaag ttcagtgtag tcccttgcct cagaaagtcc ttaaagagcg
    23101 aagtgaggga tatcgtagtc agggttacca agtactgtgg ttgctgggtc aaaaactgtg
    23161 gctcaaggag cgtttgactc gtctacagca aggttttctt tatttcagtc aaaacatggg
    23221 cttttatgtt tgggaattag acaaggaaaa acaagtttta agactcaaat acctgattta
    23281 ccaggatctc cgcggtaaac tccattatca aatcaaggaa ttttcctatg gtcaaggtag
    23341 tttattggaa atattgcgtc ttccctataa gaaacaaaaa atatctcatt ttacagtttc
    23401 tgaggacaag gacatctgtc gctatatccg gcaacaactt tattatcaaa atctcttttg
    23461 gatgaaagaa caagcagaag cctatcaaaa gggagaaaat atcctgactt atggactgaa
    23521 agaatggtat ccacaaattc gaccaatagt gggcaaattt ttccagattg aacaagactt
    23581 gactagctat tatcagcact tttataccta ttaccaaaaa aatcctcaaa atgattggca
    23641 aaagctttat ccaccagcct tttatcagca atatttcttg aaaaatatgg tagaatagaa
    23701 aggatggagg aatctaatgg tattacaaag aaatgaaata aatgaaaaag atacatggga
    23761 tctatcaacg atctacccaa ctgaccaggc ttgggaagaa gtcttaaaag atttaacaga
    23821 acaattggag acagtagccc agtatgaagg ccatctcttg gatagtgcgg ataacctact
    23881 agaaatcact gaattttctc ttgaaatgga acgccagatg gagaagcttt acgtttatgc
    23941 tcatatgaag aatgaccagg atacacgtga agctaagtat caagagtact atgccaaggc
    24001 catgacattc tacagccagt tagaccaagc cttttcattc tatgagcctg aatttatgga
    24061 gattagcgaa aagcagtatg ctgacttttt agaagctcaa ccaaagctgc aggtttatca
    24121 acactatttt gacaagctct tgcaaggcaa ggatcacgtt ctctcacaac gtgaagaaga
    24181 attattggct ggagctggag aaatctttgg ttcagcaagt gaaaccttcg ctatcttgga
    24241 caatgcggat attgtgttcc cttatgtcct agacgatgat ggtaaagaag ttcagctatc
    24301 tcatgggatt tacacacgtt tgatggagtc taaaaaacgt gaggttcgcc gtggtgccta
    24361 tcaagctctt tatgcgactt acgaacaatt ccaacacacc tatgccaaaa ccttgcaaac
    24421 caatgttaag gtgcaaaatt accgtgctaa agttcgtaac tacaagagtg ctcgtcatgc
    24481 agccctcgca gcgaattttg ttccagaaag tgtttatgac aatttggtag cagcagttcg
    24541 caagcatttg ccactcttac atcgctatct tgagcttcgt tcaaaaatct tggggatttc
    24601 agatctcaag atgtacgatg tctacacacc gctttcatct gttgaataca gttttaccta
    24661 ccaagaagcc ttgaaaaaag cagaagatgc tttggcagtc ttgggtgagg attacttgag
    24721 ccgtgttaaa cgtgccttca gcgagcgttg gattgatgtt tacgaaaatc aaggcaagcg
    24781 ttcaggtgcc tactctggtg gttcttacga taccaatgcc tttatgcttc tcaactggca
    24841 ggacaatctg gacaatctct ttactcttgt tcatgaaaca ggtcatagta tgcattcaag
    24901 ctatactcgt gaaactcagc cttatgttta cggagattac tctatctttt tggctgagat
    24961 tgcctcaact accaatgaaa atatcttgac ggagaaatta ttggaagaag tggaagacga
    25021 cgcaacacgc tttgctattc tcaataactt cctagatggt ttccgtggaa cagttttccg
    25081 ccaaactcaa tttgctgagt ttgaacacgc cattcaccaa gcagatcaaa atggggaggt
    25141 cttgacaagc gatttcctaa ataaactcta cgcagacttg aaccaagagt attatggttt
    25201 gagtaaggaa gacaatcctg aaatccaata cgagtgggct cgcattccac acttctacta
    25261 taactactat gtatatcaat attcaactgg ctttgcggcc gcctcagcct tggctgaaaa
    25321 aattgtccat ggtagtcaag aagaccgtga ccgctatatc gactacctca aggcaggtaa
    25381 gtcggactat ccacttaatg tcatgagaaa agctggtgtt gatatggaga aggaagacta
    25441 cctcaacgat gcctttgcag tctttgaacg ccgtttaaat gagtttgaag cccttgttga
    25501 aaaattagga ttggcataaa atggttgaat cgtatagtaa gaatgctaac cataacatgc
    25561 gtcgtcctgt cgtcaaagaa gaaattgtag acttgatgcg tcagcgtcaa aagcaggtca
    25621 caggtttctt gaaagaattg gaaaactttg cccgcaagga aaatattcct attattcccc
    25681 atgaaacggt tgcttatttc cgttttctta tggaaaccat gcagcctaaa aatattctgg
    25741 aaattgggac ggctatcggt ttttcagctc tcttgatggc tgaacatgcg ccaaatgcta
    25801 agattacaac tattgatcgt aatccagaaa tgattggttt tgccaaggaa aattttgccc
    25861 agtttgacag tcgcaagcaa atcactctcc tagagggaga tgcggtggat gtcttatcta
    25921 cactgacaga gtcttatgat ttcgtcttta tggattctgc caagtctaaa tacatcgtct
    25981 ttctgccaga aatcctcaaa catttggaag ttggtggtgt ggttgtcttg gatgatattt
    26041 ttcaaggtgg tgatgttgcc aaggatatta tggaagtccg tcgtggtcag cgaaccattt
    26101 atcgaggcct tcaaaaatta tttgatgcaa ccttagacaa tccagaactc accgcaacat
    26161 tagtgccttt aggagatggt attctcatgc ttcgtaaaaa tgtagcagat gttcaactgt
    26221 ctgaaagcga atgattttca gaaaaattta agaaaaaata gtaaaataga tagagtaaca
    26281 cttatctcaa aggagtagac atgaagaaaa aattattggc aggtgccatc acactattat
    26341 cagtagcaac tttagcagct tgttcgaaag ggtcagaagg ggcagacctt atcagcatga
    26401 aaggggatgt catcacagaa catcaatttt atgagcaagt gaaaaacaac ccttcagccc
    26461 aacaagtctt gttaaatatg accatccaaa aagtttttaa aaaacaatat ggctcagagc
    26521 ttgatgataa agaggttgat gatactattg ccgaagaaaa aaaacaatat ggcgaaaact
    26581 accaacgtgt cttgtcacaa gcaggtatga ctcttgaaac acgtaaagct caaattcgta
    26641 caagtaaatt agttgagttg gcagttaaga aggtagcaga agctgaattg acagatgaag
    26701 cctataagaa agcctttgat gagtacactc cagatgtaac ggctcaaatc atccgtctta
    26761 ataatgaaga taaggccaaa gaagttctcg aaaaagccaa ggcagaaggt gctgattttg
    26821 ctcaattagc caaagataat tcaactgatg aaaaaacaaa agaaaatggt ggagaaatta
    26881 cctttgattc tgcttcaaca gaagtacctg agcaagtcaa aaaagccgct ttcgctttag
    26941 atgtggatgg tgtttctgat gtgattacag caactggcac acaagcctac agtagccaat
    27001 attacattgt aaaactcact aagaaaacag aaaaatcatc taatattgat gactacaaag
    27061 aaaaattaaa aactgttatc ttgactcaaa aacaaaatga ttcaacattt gttcaaagca
    27121 ttatcggaaa agaattgcaa gcagccaata tcaaggttaa ggaccaagcc ttccaaaata
    27181 tctttaccca atatatcggt ggtggagatt caagctcaag cagtagtaca tcaaacgaat
    27241 agtccaaatc aatgagtcag ggaaaaaaac tcgacttcag gaaaaaatga agcaaacatt
    27301 cccacaataa aacgcatagt acaaggtttg tactgacccc aaaagttaga caattaattt
    27361 atctgaagga tttagttctg tattgcacag ggctaagtcc ttttagtttt accttaattc
    27421 tcttattgtt gtaataatca atatagtcta taatggcttg ttccaattga ttaagtgatt
    27481 taaatgtttt ctcatagcca taaaacattt cggattttaa aatgccaaag aaagattcca
    27541 tcctaccgtt gtcttggctg tttcctttgc gtgacataga tgcttgaatt cccttactct
    27601 ctaggaagcg atgataagaa tcgtgttggt attgccagcc ttggtcacta tggagaatcg
    27661 tattctcgta gtgcttctct ttgaatgcct gttccaaca
//
LOCUS       DAVKEV010000029        26032 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVKEV010000029 DAVKEV010000000
VERSION     DAVKEV010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26032
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.029"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(136..2151)
                     /gene="recG"
                     /locus_tag="VWZ68_001341"
     CDS             complement(136..2151)
                     /gene="recG"
                     /locus_tag="VWZ68_001341"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEU9372363.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHYMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIETWQEDPEWRMIALHLEKKEHLD"
     gene            complement(2170..3273)
                     /locus_tag="VWZ68_001342"
     CDS             complement(2170..3273)
                     /locus_tag="VWZ68_001342"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEU9372364.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLALPYDLIPALTLESALVHIKTVPAGACMGYGATYQTDSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(3263..3631)
                     /locus_tag="VWZ68_001343"
     CDS             complement(3263..3631)
                     /locus_tag="VWZ68_001343"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEU9372365.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(3670..4701)
                     /locus_tag="VWZ68_001344"
     CDS             complement(3670..4701)
                     /locus_tag="VWZ68_001344"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU9372366.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(4703..5734)
                     /locus_tag="VWZ68_001345"
     CDS             complement(4703..5734)
                     /locus_tag="VWZ68_001345"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU9372367.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(5815..8328)
                     /gene="secA"
                     /locus_tag="VWZ68_001346"
     CDS             complement(5815..8328)
                     /gene="secA"
                     /locus_tag="VWZ68_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEU9372368.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMATLTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQAMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(8474..8761)
                     /locus_tag="VWZ68_001347"
     CDS             complement(8474..8761)
                     /locus_tag="VWZ68_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372369.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     MQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            complement(8772..9422)
                     /locus_tag="VWZ68_001348"
     CDS             complement(8772..9422)
                     /locus_tag="VWZ68_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9372370.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            complement(9426..10067)
                     /locus_tag="VWZ68_001349"
     CDS             complement(9426..10067)
                     /locus_tag="VWZ68_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372371.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            complement(10060..10851)
                     /locus_tag="VWZ68_001350"
     CDS             complement(10060..10851)
                     /locus_tag="VWZ68_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372372.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILHVVPYMVLKKYEDNV"
     gene            complement(11036..11371)
                     /locus_tag="VWZ68_001351"
     CDS             complement(11036..11371)
                     /locus_tag="VWZ68_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372373.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            complement(11511..11846)
                     /locus_tag="VWZ68_001352"
     CDS             complement(11511..11846)
                     /locus_tag="VWZ68_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372374.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(11937..13247)
                     /gene="der"
                     /locus_tag="VWZ68_001353"
     CDS             complement(11937..13247)
                     /gene="der"
                     /locus_tag="VWZ68_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEU9372375.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(13261..13974)
                     /locus_tag="VWZ68_001354"
     CDS             complement(13261..13974)
                     /locus_tag="VWZ68_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEU9372376.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAKMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(13971..14867)
                     /gene="dnaI"
                     /locus_tag="VWZ68_001355"
     CDS             complement(13971..14867)
                     /gene="dnaI"
                     /locus_tag="VWZ68_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEU9372377.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(14868..16037)
                     /locus_tag="VWZ68_001356"
     CDS             complement(14868..16037)
                     /locus_tag="VWZ68_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEU9372378.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFNPKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPDYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(16038..16511)
                     /gene="nrdR"
                     /locus_tag="VWZ68_001357"
     CDS             complement(16038..16511)
                     /gene="nrdR"
                     /locus_tag="VWZ68_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEU9372379.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            16651..17016
                     /locus_tag="VWZ68_001358"
     CDS             16651..17016
                     /locus_tag="VWZ68_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9372380.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMIH
                     FGYEKEELPGVVSDYIKGV"
     gene            17021..17716
                     /locus_tag="VWZ68_001359"
     CDS             17021..17716
                     /locus_tag="VWZ68_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9372381.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            17733..18500
                     /locus_tag="VWZ68_001360"
     CDS             17733..18500
                     /locus_tag="VWZ68_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372382.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(18853..20052)
                     /locus_tag="VWZ68_001361"
     CDS             complement(18853..20052)
                     /locus_tag="VWZ68_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9372383.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLEQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(20049..20942)
                     /locus_tag="VWZ68_001362"
     CDS             complement(20049..20942)
                     /locus_tag="VWZ68_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9372384.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            21058..21138
                     /locus_tag="VWZ68_001363"
                     /pseudo
     CDS             21058..21138
                     /locus_tag="VWZ68_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            21648..21836
                     /locus_tag="VWZ68_001364"
                     /pseudo
     CDS             21648..21836
                     /locus_tag="VWZ68_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            22251..22868
                     /locus_tag="VWZ68_001365"
     CDS             22251..22868
                     /locus_tag="VWZ68_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEU9372385.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(22911..23798)
                     /locus_tag="VWZ68_001366"
     CDS             complement(22911..23798)
                     /locus_tag="VWZ68_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9372386.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(23947..25830)
                     /locus_tag="VWZ68_001367"
     CDS             complement(23947..25830)
                     /locus_tag="VWZ68_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU9372387.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFIIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFETKV
                     AQGDKVKVGDVLGTFDSNKIAAAGLDDTTMVIVTNTGDYASVAPVATGSVAKGDAVIE
                     VKI"
BASE COUNT         7648 a         5828 c         4859 g         7697 t
ORIGIN      
        1 tgcttccttc ttttggaaag tggtttggta atttacttta atcgttactg tcatatgaga
       61 gtcctcgttt ctttttgatg actttagtat aagagccaaa tctaaaaact agcttaagtt
      121 ttccttagag aaagcttaat ccagatgttc tttcttttcc agatgaaggg caatcatgcg
      181 ccactctgga tcttcttgcc aagtttctat agaactaatg tagctagcaa cctttcttgc
      241 ttcttctaaa atcggaaaat cttcgataat atcagccact tggaactctg gaagtcctga
      301 ctgtctggtt ccaaaaatct caccagaacc acgcattttc aaatcttcct ccgcaaggac
      361 aaatccattg gtcgtttctg tcatgatgcg catgcggtct ttcccagaat ccgtcttggg
      421 attggcaacg agaacagcgt aggactgctt gtccccccga ccgacacgac ctctaagctg
      481 gtgaagttga ctgagaccga agcgatcggc atccatgata atcatgacag tcgcattggg
      541 aacattgacc ccaacctcaa taaccgtcgt cgaaaccaga atatccgtct ttctctcctt
      601 gaaatcctgc atgatctggt ctttttcgtc actcttcatc ctaccatgta gaagagccac
      661 ctctgccttg cctgcaaaat gagtcgtcaa ctcctctgat aaggcaatgg catttttcaa
      721 atctagagct tctgattctt caatcaaagg agagatgaca taggcttggg aacctttttg
      781 aatttccccc tctaaccaag tcaagacctg aggtagttgc tcatgtttga tccagcgcgt
      841 cacaataggc ttccgacctg ctggcatctg gtcgataatg gaaacatcca tatctccaaa
      901 ggctgtgatg gcaagcgtcc gtggaatggg agtcgccgtc atcatgagga catctggatt
      961 gtcgcctttt tcccgtaaaa tacgcctttg ccccacacca aaacggtgct gctcatcgat
     1021 aataatcaaa ccaagacgag catactccac cccatcttgt atcagagcgt gagttcctat
     1081 aatcaaatca gcctcaccct tggcaatggt ctccaagacc tctctctttt ctgcagcttt
     1141 caaggaacct gtcaagagag ccagtttcaa attgggaaaa aggttctgta aactctcaaa
     1201 gtgttgctct gcgaggattt ctgttggtac cattagggca gcctgataac ctgctgtcac
     1261 tgccgcaaac atggccaagc cagcgactac cgtttttccg ctccccacat ctccttgtag
     1321 gagacgattc atgtagtggt cggacttcat atcagttaaa atttcctgca aactcttttc
     1381 ctgagcttgg gtcagggcaa aaggaagact tgctttaact gctgtcactt tttcctgaga
     1441 ccaattcaga accagaccac ttccctgaac tctattttca gacttgagca tctgcaactg
     1501 catttggaaa taaaagagtt cctcaaactt gatacggcga agagcctgct tgtattctgc
     1561 caaatccttt ggaaaatgca tagctcggac tgcctgacaa cgggacatga gtttgtattt
     1621 gtctagtaaa gactggggca gattttcttc tatcaagagg tccagtccct gatcaaaagc
     1681 cgtcttgatg accttgacca gactggcctg actgattccc tgagccagac gatagacagg
     1741 ctggaggtca tcttctacct gagccagaac cttcatccca gtcagactag ccttagcgcg
     1801 gtcccatttt ccaaagacag caagggttgc tcccaactct attttatcag ccagataggg
     1861 ctggttaaag aaattcaccg caaaaacgac ctctccctgc ttgagactaa aacgcaggcg
     1921 attgcgcttg aaaccataat actggacact agcaggagtc actacctgac cagaaagaac
     1981 tgccttctca ccgtcttcta gttccagcac ctgcttggtt ttgaagtctt cataacggaa
     2041 aggaaagtag agcaagagat cttgcaagtt ttcaattcct agtttggcgt atttttctgc
     2101 tgactttggt cccacaccag gcaagacatg caagggttga tgtagattca tgctccactc
     2161 ctttcttttc taataatatt ctctcggaat acggtcgctg aggaggcaaa ccacctcata
     2221 gttaatggtt acgcggtagg tcgctacctg agttgcagtg atttccttat ccccattgga
     2281 gccaatcaag gttaccttgg ttccgagtgg gtaaggctta ggcaatcgaa tagtgatttg
     2341 gtccatcgaa accctgccga caattgggca agcttggcca tctaccaaga cagagaaatt
     2401 ttgcatgtct cttgtccatc catctgcata cccgattggc acggtcgcga tgacttgctc
     2461 gctatccgtt tgataagttg ctccatagcc catgcaagca ccagctggaa ctgtcttgat
     2521 atgaaccaga gcagactcca aggtcaaggc cggtatcaaa tcataaggca aagccaagac
     2581 cgctccactt ggattgagac catacatggc atctcccata cgaaccgcat tgaaaatagt
     2641 ctctacatgc caaagagtcg ttgcagaatt gctagcatga accagctctg gaacttcctt
     2701 catactagct aaaatagttt taaaccgttc taactgggca ttaaaatagt catctgattc
     2761 ctcatcagca gtagcaaagt gggtaaagat tccttcaaca cgaacaccgt gttgttggag
     2821 caaatcttga gcctgctcaa cctcacttgc ctctctaaaa ccaatccgtc ccatccctga
     2881 atcaatcttg aggtggactg tcaatccagt taggtccact tccttatcta agagtgcttg
     2941 aatccactcc agtccagcca ctgtcaaggt gaagtcatat tctttagcta gagcaacagc
     3001 ttcgatttca gaaactccta aaatgaggat tggcttgctg agtccagctt gtctgagttc
     3061 aatggcttca tcgatattgg aaacgcaaaa gccatcaaca tcatcttgaa ttgccttggc
     3121 aacggcaaca gctccatgac cataagcatt ggccttaacc acagccaact tgagcgttcc
     3181 ttgagggata tgagccccca tttgctgaat attttgtcga atagctccca gatgaatcag
     3241 agccttggtt ggtctatgtg gactagcttt catgattttc ctccaaaatg acactggctg
     3301 tcacaaactg atcggtgtgg ctgatagaca gccaaatctt tcctgaaaat ggtgcctgac
     3361 taaaataagg cgccccacgt tcattgttca atacttccaa atcctgaaaa ccgagcttgc
     3421 taatgcccgt tcccatagcc ttggaaaagg cctccttagc cgaccagcga ccagctaaat
     3481 attctatttg cctgcgtcct ttgagactgg tgaagcgctc catttcctga gcggtcagta
     3541 cacgcttagc aaatccttca tgtcgtgtaa ctgcgctttc tatcgaagcc aattcttcga
     3601 tgtcaattcc gtgtccaact atcattctca tcaaaaggag ttgagattcc ccaactccat
     3661 ccttttcact tattttgtca aggtaacata aatctcttct accaaggcct ctgtattttc
     3721 ccaacctagg caagggtcag taatagagca accaaagatc tctggttggt tttgacgacc
     3781 atctgctagg taagattcaa tcataaatcc tcgaaccgtc tttttaattt tctcattcca
     3841 atcacgattc tgcaaggtct ggcgaacaat tcgaatctgc tccatatatt gcttgcctga
     3901 gttatcatgg ttggtgtcaa tgaggataaa aggattttca agtcccatgg tttcatagcg
     3961 ttcaatggct tggagtaggt tttcatagta gtaattcggc atataattgc catactcgtt
     4021 gactgctcca cggaggataa catgggccaa aggattacct gatgtctcaa cttcctgccc
     4081 atgataaagg aaggtttgct tgttttgagc agcatagatg gcgttaaaca taacacccaa
     4141 atttcctgag gttggatttt tcatccctac tggtgcatca atcccagaag ccacaaagcg
     4201 gtgctcttgg tcttccacag aacgagctcc aacggcatgg tagctgacca agtcatccac
     4261 caagatcaga tttgacggat aaagcatctc atctgccgtt gtcaaaccag tctctgtaat
     4321 cacgcggtaa tgcaactggc gcacagcctg caaaccgtta atcaggcttg gagccttaga
     4381 agtatctggc tggtgaacca atcctttata gccgtctcca ttggtacgag gcttagcagt
     4441 atacacgcgc atgaccatga aaatcttgtc cgctaccttc ttttgcaagg cggataaacg
     4501 gcgagcatat tccaagaccg cctcttcatt atcagaagag caaggaccaa tcaccaagag
     4561 aatacggtca tcttcccctg aaataatatc tgccaattcc ctgtcacggc tttccttgag
     4621 tctcaaggct tccgcagaca attgggtttc agccttgatg acttccatat cgatttcttg
     4681 acctttttca ataaatgcca tcttattctc ctaacgtttt gtaaatttct ctgacaagag
     4741 cttctgtgtt atcccaaccc aggcaagggt ctgtgataga cttgccaaat acttctggct
     4801 cattttgtcg accatcttcc agataagact caatcataaa accacgaacg aactgcttaa
     4861 ttttttcatt ccaagcacgg ttaatcaagg tctggcggac aattcggatc tgttcaatat
     4921 actgcttacc agaattgtca tgattggtat caatgatgat aaaaggattt tccaagccca
     4981 ttttctcata ttgggcaatg gtatcaatta aattgtcata atagtagttg ggaatatttt
     5041 ttccatactc attaagagca ccacgaagaa tagcgtgtga aagcgggttc ccagttgttt
     5101 ctacttcttt tcctaagaaa aggaaacttt gtttgttttg agcagcataa atcccattaa
     5161 acatgacatt gagatttcca gaggttggat ttttaaaacc agtagaaaat cctgccccac
     5221 ttgccacaaa gcggtgttgc tggtcttcaa ctgaacgggc accaactgcc atgtaagaaa
     5281 tcaaatcatc tacaagcgga aggttttcag gataaagcat ttcatcagca gttgtcatcc
     5341 ctgtttctgt gatgacacga tagtgaagat ggcgaacggc tttgattcca ttgataagac
     5401 taggcgcttc tgtcgcgtta ggctggtgaa tcaagccctt atagccatct ccgttggtac
     5461 ggggtttggc agtataaaca cgcataacca taaagatacg atctgccact tcttcttgta
     5521 ggactgccaa acgcttagcg tattcaagga cagcttcttc gttgtcagat gagcatggcc
     5581 cgattaccaa gagaattcgc tgatcttctc cacgtataat ggcttctagc tcttgatcgc
     5641 gctgtgattt cctctccaaa gcctgacctt ctaattttga caaggcacga acttcttcta
     5701 tatttatttt agagcttttt gctgtaaata ccataactca tctccttata aagcaaacgg
     5761 atacccagta aaaatttact tttcacaaga tatccgcctc taaactatct cattttattg
     5821 tcttttaccg tgacagtttt taaatttctt accagaacca catgggcaaa gttcattgcg
     5881 tccaatctgg ctcaaatcca aatcttctgg catacttgct tggtgagcag cgatattgcg
     5941 agtcgctgtt gtactgatat gacgttctgc ctgtggtctt tcttgttcat gaatttgtgc
     6001 tttcatcatc aagcgtgtca catcaaactc aatcgaacca atcatatcat taaacatacg
     6061 gaaaccttct gcctgatact caacaacagg gttgttctga gcatagccac gaagtccaac
     6121 cgcgttacgc aattgatcaa gggcatcgat atgatctgtc cacttgttat ccaccactcg
     6181 tagaatcaaa actttttgga attctttaac tgcttcttca tcgcgtagtt ttgaaacctg
     6241 actatcgtaa accttcaagg cacgttggaa aagctcttcc ttgatggcct tatcagacaa
     6301 gcctgacaag tcttccatcg taatagaatc ttcaggaagc aagttgtact tagcaaagtt
     6361 caaaattgcc tctagttttt catcttgttt ggcacgcgca tgaccatcaa cgacacgttc
     6421 aatcgtgcgt ttgatcatag cctgaatttc aggtgccaag tcacgatctg cagtgatgac
     6481 atcgtaacgt tgagcataga taatctcacg ttgttcacgc atgacatcat cgtattgaag
     6541 gacttgttta cgggtatcgt agttatttcc ttcgacacgt ttctgagctg cttcaacctg
     6601 acgcgtcaac atgcgagact caatcgcctc ttcagacatg ttcaaacgtt caaagattcc
     6661 cttcaagcgt tcagaaccaa aacgtttcat caaatcatct tcaagagata ggtagaattg
     6721 tgactcacct ggatctcctt gacgacctga acgtccacga agctggttat cgatacgacg
     6781 actttcatga cgttctgtac caataacaca aagtcctcca agttcacgaa caccttcacc
     6841 aagcttgatg tcggtaccac gacccgccat gttggttgcg atggtaacgg caccacgttg
     6901 accagcattc atgatgattt gggcttctct atagtggttt ttggcattca agacttcgtg
     6961 aggaacacca gctgcaacca atttcttaga aatgtagtca ctagtttcaa ccgccactgt
     7021 accaaccaag acaggttgac ccttttggta acgagcctta acgtcttcga caaccgcttt
     7081 aaacttagat tcgatacttg cataaagaag gtctgagtgg tcaatacgtt gaacaggacg
     7141 gtttgttggg attggaataa cacgaatgtt gtagatttca cggaattctt cttcctcagt
     7201 cttacctgta cccgtcatac cagacaattt cttgtacata cggaaaaggt tttggtacgt
     7261 gattgaggca gatgtcttgg tttcatcctg gattggcaca ccttctttgg cttcaatagc
     7321 ttggtgcaat ccatcagaat aacgacgacc ttccatggta cgacctgtaa attggtcgac
     7381 aatcaagatt tcttgctctt cgctcaccac atagtcaata tcgagaagca tgatgtagtt
     7441 ggcacgaagg gcgttatcga taaagtgagt caaagccacg ttttcgatgt catagaggtt
     7501 ttcaagtttg aagtagcttt cagccctgtc aatccctgaa tcagacaaac caatagtctt
     7561 agactgcaca tcgatgatgt agtcatcttt gttcaaagat tttacatagt ggtctgccat
     7621 gtgatacaac tgactggttt caaccgcatt ggcacctgat acaatcaaag gtgtacgagc
     7681 ctcgtcaatc aagatagagt caacctcatc gaccaaggca tagttaagcg gacgttgtac
     7741 catgttttcg gcgcgaacga ccatgttgtc acgaaggtag tcaaatccga tttctgagtt
     7801 agttgagtaa gtaatatcac actcataggc ttcttttttc tccattggag atttggtagc
     7861 caagttaatc cctactgaca aaccaagcca agagtacaat tcacccatct cagtcgcgtc
     7921 acgttctgac aggtattcat taaccgtaac tacgtgaacc cctttacctg aaagggcatt
     7981 gaggtatacc ggcatggtcg cagtcaaggt tttcccttcc cctgtacgca tctctggcac
     8041 gtcaccatgg tgaagaacaa tcccccccat gacctgaacc ttataaggga agagacctag
     8101 gacacgtttg gcaccttcac ggacaaccgc aaatgcttcg taaagcaatg aatccagtga
     8161 ttctccattt tgataacgtt ccttaaattc aactgttttt gcttttagtt ggtcgtcagt
     8221 caaagtagcc atttggtctt cgtatttgaa aaccttgtca gccatctttt ccagacgacg
     8281 gatttctcct ttatcatttt cgataattgt ttttaaaata ttagccatgt ttttccttac
     8341 tttaaattcc gaatatttta gaatgttcct ttaattttag cacaattact gattattttc
     8401 aaggaagaat ccccattttg aaaaggaaaa agaggttagt tttcaagcta acctctccga
     8461 cttttatgac tgtttaattg ccaaaaatcg gcaaaatggc aaatgtgata aataagttaa
     8521 tccaaagaga aagacagcaa atcagtccaa aaacaaagag actgactttc ttggacagca
     8581 aggccatgag aatggacaga attccaaaag ctagcaagat tttctgcatg atgaagatgt
     8641 caatccttac ccccagaatc gctctatccc aagggataaa gaagaaagac agccagatca
     8701 gcagaactaa accaatataa accttggaat agcgtgtaat aaatgatttt agatgtgcca
     8761 taagccatct cctaggattg tatatccttt acatattgta tatgtccatt ttcgacaact
     8821 aatacatctg tacaaaggtc tgaaatatct tccgatatgt gcgacgtcag gataaccaga
     8881 ccattttctt ttttcaggta agataaaatg acctgtttgg ttaacctcac actcttctca
     8941 tccaaagcat tcataggttc atcgagaaag agtatagaag gagaggaaat aaaggcttga
     9001 atcaaggcca ttttttgctt tgttcccaag gataaatgac ggtattcaac gtcttcaaat
     9061 tcctgtaaat catagtattg aatccaatag gcaattcttt tttccgtaac tttagatgaa
     9121 aaatacctta acagttccaa attttctctc agggataaat gagataaaaa ctcgactttt
     9181 tcaattaaaa ttcctgcatc ctgaatataa tgatttttta ccccgtaaac tttaccatct
     9241 tgaagaactt ttcctttgtc aagcttaata taaccagcaa gtatctttaa aagaaccgtc
     9301 ttgccagatc cattatcacc tttaagtcca taaatttttc ctgattgaaa caccaaattc
     9361 aactgattta aaataggtct tttcccataa attttctgtc catttataat ttcaagtctc
     9421 atcgtttatc ctttcttaaa tttctcttcc aagcgactaa caatcaacat aactaataag
     9481 cttaagagta ctaaatacac tgttacaata tgatccatca tccattcttg tcccacaaat
     9541 gccaaaaaat agagaaaaaa agaaaaacca gcgcccgcac taatcagtgc tatcagataa
     9601 gacagtagta agtacaacat cattaactga gcaagtaaaa agaaaagtgc gactgttttg
     9661 aaatgaattc ctagcggaag taaaccaaga aaccagacaa acaaatcttg agtaaaaaat
     9721 ttagaaatga caaccaatcg tttccttgta taatcgaaaa aggagcttga ttgatagcga
     9781 atcaagtgat ggtaatggtc tgccaaatca ctttcaagta aaatgacaga gagccatcct
     9841 accatgaaaa gcgaaaggtt taacaagagt ttggggattt ctaaattcgc ttcagaatag
     9901 tcattatagg aaaaaattga aatcaattct ctcttgaaaa agataacagc atcctgcttt
     9961 tgaaccgctg ttgacaatag atagtttatc aaaatcatca tcagaactat acgaagtagt
    10021 aaaacgatct ttctctttag ccaaatattg ttaaaattct taaacattat cttcatattt
    10081 tttaagtacc atataaggga caacatgaag gatataagga gtaaagagtt tcatcaaact
    10141 tacatcccca tagctagctt gcatcaaact cgtcatagga accatatagt aaggcaaggc
    10201 actatagagc agcatagaac caagccaaag aaacatcaaa taggtgattg ccgaacgagt
    10261 cacattcccc acataatcaa ctatttgtaa aaaatagatt gcattgatga aaataccgat
    10321 tagtaggaca caagtaaaga acaaatagct ttttatctct ccatctagga gtctttgtaa
    10381 accactccca tcagaaaata gagaattcca ttcaagagga gaaaaagtcc caaagaaata
    10441 ggttataatt gcaattatca gcacagtcac taaatatatc aaacaaggga tacttgcaac
    10501 ttgcaaagtc aactttcttt ttaacccttg atagctcact tctcttccaa tactcaatcg
    10561 taaaacttta tttttcagct caatatattg aaaacctagc aaaacaatga tgattggaat
    10621 aataaatgat tgataaaaac ctagattgaa ctggagaata cgaaaatcta atgctgattt
    10681 taataagtca tttttaattg cttgtccatc gaatttagct agatcgggcg catgaatatc
    10741 aaaaaagaaa taagtcatca aaacatcacg ataaaccaaa gcaagaaaaa gcaaagtaag
    10801 caagacataa acaaatttat gccttgccaa agttaagaga ggaatcttca taagccacct
    10861 cctacaaata gaaagtaata taatactcaa tgaaaatcaa agagcaaact aggaaactag
    10921 ccgcaagttg ctcaaagcac tgctttgagg ttgtagataa gactgacgaa gtcagttaca
    10981 tatataatcc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt ataaatcaat
    11041 gccttccgcc tttagacttc cctagttccc gtctcaagtc aagcattttt ttgaaacaga
    11101 tatagtctaa ccagtcacta gcaaaagcga taagtagtaa taatagccaa ataccccata
    11161 acttgatatc tgtcaaattt ctcaagacga tattgaaaaa cagaactgaa aaaactgtcc
    11221 aagcaaggct aaaaagagca tagagggtga tgtaaatcca gtaaaaatag taaaaaattg
    11281 ggaaaatctt actatctctg tttgcctttt caatccagct gaaaaagtaa aaacagggta
    11341 ataagattat cattttaaac aagtattcca tcacaaacct cctcttttaa attgttttct
    11401 ttagtttcgt tctattaaat gttattacca atataaacct tggaatagcg tgtaataaat
    11461 gattttagag gtaccataag ccacctccta caaatagaaa ccgatataaa tcaatgcctt
    11521 ccacccttag acttccctag ttcctgtctc aagcgaaaca tttctttgaa acaggaataa
    11581 gttaaccaat tcataccaat agctagcaga ataaaaagaa accaaatgcc ccataacttg
    11641 atatctgtca catttctcaa gacggtattg aaaaacagaa ctgaaacaac tgtccaagca
    11701 aggctaaaaa gagaatagaa ggggatgtaa aaccagtaaa aataataaaa aattggaaaa
    11761 aacttactat ttctgttggc cttctcaatc cagttatcaa aataaaagta cggtgctaaa
    11821 agtaagaatt taaacaaatg ttccatcacc gacatcaccc tccttctttt gatagcgttt
    11881 tctattattt tattatatca aaaaaatccg gaactgtcat tccagattct acttttttat
    11941 ttgcgttttc ttgcgatgag atgaatcggt gttccctcaa aaacaaaggc cttgcggatt
    12001 tgattttcca agaaacgcag gtaagaaaag tgcatgagtt cttcttcatt gacaaagatg
    12061 acaaaggttg gtggtttggt tgccacttgg gtcgcataga aaatcttgag acgttttcct
    12121 ttgtctgtcg gtgttgggtt gatggcaatg gcatccatga tgacatcgtt caagacagct
    12181 gatggaatac gtgtattttg actttcgctg atttgcttaa tcatctcagg aagtttgtgg
    12241 agacgttgct tggttaaagc tgatacaaag ataatcggtg cgtaaggcag gtattggaac
    12301 tgctcacgga tatcttcttc ccagtttttc atagtgtggt tatctttttc aagcgtatcc
    12361 cacttgttga ccacgataat catcccttta ccagcttcat gggcaaatcc tgcgatacgc
    12421 ttgtcgtact cacgaatgcc ttcttccgca ttgatgacca tcaagaccac atctgaacgg
    12481 tcaatagcac gcatggcacg cataacagag tatttctcag tattttcata aaccttacca
    12541 gacttacgca taccagccgt atcaatcatg gtaaactctt gaccatctgt atctgtaaag
    12601 tgggtatcaa tggcatcacg agttgttcca gcaacaggac tagcaataac acggtcttct
    12661 cccaagatag cattgatcaa gcttgatttt ccaacgttag gacgaccaat caagctaaac
    12721 ttaatgacat ctggattttc ttcctcatat tcatttggaa gattttctac gatcgcatct
    12781 agcacatccc ctgtaccgat tccatggaca gatgagatag gcaatggttc acccaaaccg
    12841 agagcataga aatcatagat atcatttctc atctcagggt tgtccacctt gttgactgcg
    12901 aggataactg gtttgtgggt cttataaagc ttacgggcta cgtattcgtc tgcatcggta
    12961 attccttcct taccggacac gacaaagacg ataacatctg cttcttccat ggcaatttct
    13021 gcctggtgct tgatttgttc catgaaagga gcatcgacat catcaattcc tcctgtatca
    13081 atcatgctaa aagaacgatt gagccactca cccgttgcat aaatacggtc acgtgtcact
    13141 ccttcgacat cttctacaat ggagattcgc tcaccagcga tccgattaaa tagggttgat
    13201 ttcccaacat tgggacgtcc tacaatggca atagttggta gggccataat ttctcacttt
    13261 ctacaataat ttcttctgtt caagattttt tctagttgag cttggttcag cttgaccaaa
    13321 ctgttctgct aggcgctgac tccagcttgt ggtcgcacgc gccccagcat agtcagcctg
    13381 aacacggtca taagcttgga ttgcctcagt tgactgttct tggtattctt cctcaaagac
    13441 aacattctct agtggcagtc tcggtttcat atcatgatgt tgatttggca cacccagtgc
    13501 catcccaaag acagaatagg tgtagtcagg taggttaaag agctctgcca cttcttcaga
    13561 cttgtatcga accaaaccga taatcacacc accatagccc aagctttcag ctgccaacaa
    13621 ggcgttttgt ccagcaagag ctgcatcgac cgaactaatc aagagacctt ccacaccttg
    13681 gggttggaag gtgtcggtat gaagtcgggc tcccttttct gctcggttca aatctccgac
    13741 aaagagaagg aaaacagcag actggcgaat ggcttcttga ggtaccaatt catacaaggc
    13801 atctttcttc tcttgacttc gtaccacaat cacagagtag gattggaaat tcttccaaga
    13861 tgatgccatc ttggctgctg tcaaaatctc atttaagtct acttggggaa tttcttgctc
    13921 tttaaacctg cgcactgaag tatgagcctt catcaattta atggtttctg tcatcgacgg
    13981 tttactcctt ctaaacgagt ctcctcagcc aaataacgga tgcgttccat gacccgtctg
    14041 gcttcccagg tttcgtcatt tccatgtttc actttcgcaa aatgcttctc caaatcttca
    14101 aagttgaagt tggatgtgaa aaaggtcggt aaattttcct gcatccgata ttggagaatg
    14161 acctgcagga tttcgtcacg cacccaagcg gttgattgct cggcgccaat atcatctaaa
    14221 atcaggacct cagacagctt aatctcatcc accaaggtct taacattgcc atcactgata
    14281 gcatttttga catcaatgac aaagctagga tagtggagga gagttgatga aacaccacgt
    14341 ttttctgata aatcatgagc taaggccgcc accatgaaac ttttacccac accaaagtct
    14401 ccatataagt aaagaccttt tcgaatagct ggatattgct ccacaaaggc taatagtttt
    14461 tcaaaaactg gcaagcgtcc caaatcatcc aaatcaactt gagccaaact agcttttttg
    14521 agactggctg gtagattgat tagcttgaga cgattcttaa tagccgcttc tttttcagcc
    14581 gcgattagct caggagtttc ttcatatgaa acatctgcat agccatgatt cttaaccaaa
    14641 atcggcttgt agcctttggc aatataatcc gtatccccac ggagaaactt gtcacgctcg
    14701 gtgatgtact gattaaactt ggagatactg cgatttaatt cctctggagt caaggattct
    14761 tgctggataa aagccgcaac atcagggtcc ttcatgattt tctggaccaa atcttgataa
    14821 taaaaacggc tgggttgacg tttgagtacg tctccgacac tttccatcta atctcctcct
    14881 ttttctaatc gagctaatag ttcttgtttc ttacgttcta gttccagacg agtttcctcg
    14941 ctggtttcat tcttataatc tgggttactc catttaggaa tattggtttt tgctggggca
    15001 gtctgattct gtttttgtgt ttttgttttc tgccctcgct cacgaattcg taaaacggcc
    15061 tcttctgctg aatgtatctt ttgataggca tagtcattag ccaccttcat ggcatatttc
    15121 tcattgatgt ttgccgaatc caccttatta aaggtcaaca agagaatgat attgatgact
    15181 tcgtccagca agcccaagcc agccatctgt tgcaaaagtt ctctttctgt ttgggtaatg
    15241 gtccccttgc gtgtttgctt gatttctgct aagaactgca gggcagtctt acttttagct
    15301 tccttgataa tggttgcttc cttaggatta aagtcagagg aaactggttt ttgagcaatt
    15361 ttttcacgca tgcgtttggt tgaaataacc tgagaaacag ctgttgactt ggccaattga
    15421 taggtttcaa accaagtcca tttcttctcc tcggcaatag caaagaggtt taagacatcg
    15481 gactgctcat ccgcaaaacg aagtccatct cgagccatca gctggcgaaa atgttccaag
    15541 tcaaaatcat tggccacttt cttcttgaga ccaaggtctt cttgactgcc tagttctgcc
    15601 aattctggaa agacttgatt gagtgagaca ggtatttctt caccatcagc actttcaact
    15661 ttcaaatcct ccacagcaga gtcgccaatc tttttctcta agagtctgcg ataaacagga
    15721 tgctccaaga agtcttgact agatagagga gcatggaggg ctagctgata aacatccccc
    15781 ttttgataga gggtcaagag attaaaagca gataagattt tcaatgattt tatcagtcta
    15841 tccatcccaa agttgagatg attgaggata cttgaaaaaa gatattcctt tctaccatta
    15901 tcccaaaaac tgattgtata aagataaagg ctcagtgcct cctgaccgat aatcgggagg
    15961 tagcactgta ccagagatga ggtatcttgc gacacccgat tattctttag ataagaaaaa
    16021 cggtcaattg gcttcattta tctttccttt ttctttttag aggactgggt gatttgttgg
    16081 agcaagctct ctaactcact gacatcctta aaactacgat agacactagc aaaacgtaca
    16141 taggtaatct cgtccaattc agccaactcc tccatgacga gtgaaccaat gtcctcactt
    16201 tgaatttcat tttcatttcg accacggagt ttctgttcga tacgattgac taccatgttg
    16261 atttcatcac ttgacacagg acgtttctgg gctgagcgga taatcccatt aaagatttta
    16321 tctctggaga attgttcccg tgtaccatct tttttaacaa ccactaaggt tctttcttct
    16381 actcgttcgt aggttgtaaa acggtgttgg cattcgtcgc actcacgtct tctacgaatg
    16441 gtgttccctt cttctgcttg gcgactatcg ataacacttg acttggtagc cccacatttt
    16501 ggacaacgca tcctttccct ccttatcgtt ttcttttcat tataccattt tttaagcgat
    16561 tcccaaaaca attcttcttt ttgcttgaca agttttttgt tttgttgtat tatttagtta
    16621 agacaaaagg ataagagaaa ggagactaag atgtcctgga catttgacaa caaaaaaccc
    16681 atctatttac agattatgga gaaaatcaag cttcagattg tttcccatac actggaaccc
    16741 aatcaacaac ttccaaccgt gagggagcta gctagcgagg ctggtgtcaa tcccaatacc
    16801 atccaaagag ccttatcaga ccttgaacga gaaggatttg tctacagcaa gcgaacaact
    16861 ggacgatttg tgactaagga taaggagcta atcgctcagt cacgcaaaca attatcagaa
    16921 gaagaattgg aacacttcgt ttcctccatg atccattttg gctatgaaaa agaagaacta
    16981 ccaggcgtag tcagtgatta tattaaagga gtttaagcct atgtcattac tagtatttga
    17041 aaatgtatcc aaatcatatg gagcaacacc agcccttgaa aatgtttctc ttgacattcc
    17101 agctggaaaa attgtcggcc ttcttgggcc aaacggctca ggaaaaacaa ccctgattaa
    17161 actaattaat ggcctcttac aaccagatca aggacgtgtc ctcatcaacg acatggaccc
    17221 aagcccagca accaaggccg ttgtagctta tttgcctgat acgacctatc tcaatgagca
    17281 aatgaaggtc aaagaagccc taacctactt caagaccttc tataaagatt tcaatcttga
    17341 acgcgctcat catctacttg cagacctggg cattgatgaa aatagtcgtc tcaagaaact
    17401 atcaaaagga aacaaagaaa aggttcaact gattttggtt atgagccgtg atgctcgtct
    17461 ctatgttttg gatgaaccca ttggtggggt ggatccagca gcccgtgctt atatcctcaa
    17521 taccattatc aacaactact caccaacttc taccgttttg atttctaccc acttgatttc
    17581 tgatatcgag ccaatcttgg atgaaattgt cttcctaaaa gacggaaaag tcgtccgtca
    17641 aggaaatgta gatgatattc gctacgagtc aggtgaatcc attgaccaac tcttccgtca
    17701 ggaatttaag gcctaagcaa aggagattat ttatgttttg gaatttagtt cactacgaat
    17761 ttaaaaatgt taacaagtgg tatttagccc tctacgcagc cgtgctagtc ctttctgccc
    17821 tcatcggaat acagacacaa ggctttaaaa atctacctta ccaagaaagt caggctacta
    17881 tgctactttt tctagctaca gtctttggtg gcttgatgct tacacttgcg atttcaacca
    17941 ttttcttgat tattaaacgc ttcaaaggta gtgtctacga ccgacaaggc tatctgactt
    18001 tgaccttgcc agtttctgaa caccatatca tcacagccaa actaatcggt gcctttatct
    18061 ggtcattgat tagcaccgct gtattggctc taagtgctgt tattattctg gctttaacag
    18121 ctccagaatg gattcctctt tcttatgtga ttacatttgt agaaacacat ctccctcaga
    18181 tctttcttac aggtatatcc ttcctactaa ataccatttc aggaatcctc tgcatctacc
    18241 tggctatttc cattggacag cttttcaatg aataccgtac agcactcgct gttgcagcct
    18301 acattggtat ccaaatcgtc attggattta ttgaactttt cttcaatctt agttctaatt
    18361 tctatgtcaa ttcactggta ggactcaatg accatttcta tatgggagca ggtatagcca
    18421 ttgttaaaga actcatattc atagctatct tttatctcgg aacctactac atcttgagaa
    18481 ataaggttaa tttgctttaa ataattttta cctagatatg taacatactc atagaacaaa
    18541 agagaccagg caaaaagtct ttaaaattag aaaacgcata gtatcaagtg ttaaaaatcc
    18601 ttgatattat gcgttttttg tgagctgact tatttccttt cactatatcg caaaatgaaa
    18661 taagaacgga acgatgggat tttggaattc aaatcaattt ataagaatgt tttagaagta
    18721 atattatcct attccagatt cagttcacta tacaattgag ttttcaagca acctgtttac
    18781 ataatgtgta cataattagg ttcgtgattc catccttttc atctttaaaa acctcgcttt
    18841 cgcaaggctc ttctatttat aagataaggc acgtttaaag gttttccaaa tccctaaatc
    18901 atccgtttga agaacgagac tagcatacat gcgtccgata aatcctgttg ctaccaccgc
    18961 aaaaatcact gtaatagcaa gtgaaatcca tgcttctgct ccccccgcat agccattaat
    19021 cgttcgaaac ggcataaaga aggtcgaaat aaagggaata taagaaccaa tcttcaagag
    19081 gagattgtca ccagctgcac ctagagctgt cactccaaaa aaaccaccca taatcaaaat
    19141 catcaaaggc gacaaggctt tccctgagtc ctcaggacga gaaaccatag atcctaggaa
    19201 tgctgccaag actacgtaca tgaaaagact gatcaaaata aagagcaagg tattcagtga
    19261 gatagcatct cccaagtgat ccaaaatacc agactgagcc aagaatggca aatctttaaa
    19321 gagcaaaacg gcagccagac cacctacaac atagatccca atatgcgtta aaatcactag
    19381 aaacagagcc atcatccgcg catagaaata gtgacttgcc cttatgctag aaaaaacgac
    19441 ttccataatt ttggtgcctt tttcactggc aacttcctga gctgttacac ccgcataggt
    19501 aatcagaatc atataaagaa agaatcctaa ggcacctgct gcaattgttt gaataaactt
    19561 tttattttcc ttggcttcat caatcttttc tgtgaattga attgtctgct ctaagcgttt
    19621 ttcctgctct tgagacaagg aagcagttga acgattaagc tgattttgca gttcattgag
    19681 tgtacctgta acctcaaatt taattccatt ttcaagcgat gtttcgccat gataaactgc
    19741 ctttagaaca ctatcttctt gatcaatggt caaataacct tttaattttt cttctttaat
    19801 tgcttctttg gcacttgctt cgtctttata gtcgaagtta acaccattta cattcttcag
    19861 tccttctgct acagatggca ctgttgtcac tactgccact ttattatttt tagccataga
    19921 agaaccttgg agatgcccaa ttcctacaga gattcctaaa aagaggaacg gcgaaatcac
    19981 cataaagaag aaactccatg actcgacatg tcgaagatag gtttccttga ttacaaccca
    20041 catatttctc atacttccac tcctgattct agtttaaaga tttcatcgat agttggcgct
    20101 tgttggtcaa atgttgcgat atattgacct tgagtcaaga ttgggaagag ttcccttcca
    20161 gcgctctcat cctccaaaat caatttccaa ctgccttgtt tggtcaagct cacctgtttg
    20221 acatgaggaa gattttccaa ttcttccttg cttcgttcac ttgaaacaaa gagacgcgtt
    20281 ttcccgtatt gattgcggac atcctgaact ggtccgtgca agaccacacg gccatctcgg
    20341 atcatcagaa tatcgtcaca aagttcctca acattggtca tgacatggtc agaaaagata
    20401 atggttgctc cgcgctcttt ttcctgaaaa atgacttgtt tgagcaattc tgtattaact
    20461 gggtccaatc cactaaaagg ctcatccaag ataatcaggt ctggttcatg aatcagagta
    20521 ataatgagct gaatcttctg ctgatttcct tttgacagac tcttgatttt atctgtcagc
    20581 tttcctttca cttccaacct cttcatccat tgagggagtt tttctttgac ttctttggca
    20641 tccatgcctt ttagagtcgc caagtagcga acttgttcaa gaactgtcaa tttaggcatg
    20701 agactgcgtt cttcaggcag ataaccaatc cgagcatagg tctcctgacg aatatcctga
    20761 ccatccagac cgatttctcc ctgatattct aggaatttca aaatactatg gaaaatcgtt
    20821 gtttttccag caccattttt tccgactagt cccaaaatac gacctggtcg cgcttgaaag
    20881 tcaataccaa acaaaacttg cttggagcca aaacttttct ctagacttct tacttctagc
    20941 atctttcacc tccgaaattt cttgcactca ttatactcct ttttgatagc ctttacaatg
    21001 tttttgtcca tttttagaag actattgctg tgtaaaatat ggcctggagc acttttatac
    21061 tcaatgaaaa gcaaagagca aactaggaag ctagccgtag gctgctcaaa gtacagcttt
    21121 gaggttgcag ataaaactga cgaagtcagc tcaaaacact gttttgaggt tgtggataga
    21181 actgacgaag tcagtaacta tatctacggc aaggcgaagc tgacgtggtt tgaagagatt
    21241 ttcgaagagt attagtgata aatccattat acagtagcaa acttaattta taccttccgc
    21301 tcctcaactg tctattttta atcctgaatt gttatttgag taactccttt ttcctcgtaa
    21361 agttttcttc ctctaaaact tctggaaaaa ggctaatagt ttcagacaac atttttataa
    21421 gaaacaagtt catctgtcat ttcaagaagg agtaatcctt tatctactaa tggacggaac
    21481 ggaattcaac cgcttgtccg atatgttttc taaggattat atagtaaaat gaaataaaaa
    21541 caggacaaat tgatcaggac agtcaaattg atttctaaca atgttttaga agtagatgta
    21601 tactattcta gtttcaatct gctatatcta ttatgcacat cactatagga tctaatgaaa
    21661 atcacaacag gctcattcat agatggttac ctcagggaac taagaaaaca actacaaagg
    21721 aagtcgcatt tatcgaaaag tggattaaca actatcctaa aaaatgcttg aactacaagt
    21781 cccccagaga agacttctgg atgactaact tgaacttgaa atttagcaat aattaactca
    21841 ccatctaact atatttagta attatttcag aactgattaa tattaaaatt aactaacaat
    21901 tcaaaggatt catactagcc ataaattacg tccatcagag agagactctt actactttta
    21961 tattttagtc tttctagctt cagaatacat ataaacttta gggaaaatga ctattcgaaa
    22021 gcgcgaatgc ctcaaaatta tcccagataa gctattcgaa acttagaata cttttaaatt
    22081 tatggaattg cgattattcg aaacctagaa tgcatataac ctttagttga cagacctatt
    22141 ctaagtctcg aagggctatt tactttctat tccttatcaa aaaagactca ttcccccttt
    22201 ctcctccaaa atatggtata gtagaaatat actatctatg aggagtttac atgtcacagg
    22261 ataaacaaat gaaagctgtt tctccccttc tgcagcgagt tatcaatatc tcatcgattg
    22321 tcggtggggt tgggagtttg attttctgta tttgggctta tcaggctggg attttacaat
    22381 ccaaggaaac cctctctgcc tttatccagc aggcaggcat ctggggtcca cctctcttta
    22441 tctttttaca gattttacag actgtcgtcc ctatcattcc aggggccttg acctcggtgg
    22501 ctggggtctt tatctacggg cacatcatcg ggactatcta caactatatc ggcatcgtga
    22561 ttggctgtgc cattatcttt tatctagtgc gcctatacgg agctgccttt gtccagtctg
    22621 tcgtcagcaa gcgcacctac gacaagtaca tcggctggct agataagggc aatcgttttg
    22681 accgcttctt tatttttatg atgatttggc ccattagccc agctgacttt ctctgtatgc
    22741 tggctgccct gaccaagatg agtttcaagc gctacatgac catcatcatt ctgaccaaac
    22801 cctttaccct cgtggtttat acctacggtc tgacctatat tattgacttt ttctggcaaa
    22861 tgctttgaca cgtaaaaaat ccgtttggtt tcccaagcgg attttgtgct ttattttgaa
    22921 acttcttttg caagaacaaa gttcccaagt gtggcagaac catttcctgc gactgctggc
    22981 gtcacgatat agtcacgcac atctggtact ggtaggtaac cattaagaag agatgtaaat
    23041 ttctcacgga cacggtccag catatgttgt tgagccatga cccctccacc aaagacaatc
    23101 acgtctgggc ggaaagtcac tgtcgcatta accgcagctt gagcgatata gtaggcttga
    23161 acatcccaaa cagggttgtt gagttcaata gtttccccac gtacacctgt acgagcttcc
    23221 aaacttggac cagctgcata accttctaga catcccttat ggaaaggaca aacaccctta
    23281 aactcttttt caatatccat tgggtgtcta gcaacataat aatgacccat ttcagggtga
    23341 cccacaccac cgataaactc accacgttgg atgacacctg caccgatacc tgtaccgatt
    23401 gtgtagtaaa ccaagttttc gatacgacca ccagcattgt tacgggcaac cacttcaccg
    23461 taagcagagc tgtttacgtc tgttgtgaag tacattggca catttagggc gcgacgaagg
    23521 gcaccaagca agtccacatt tgcccagttt ggttttggag tcgtcgtgat aaagccataa
    23581 gtttttgagt ttttgtcaat atcaatcggc ccaaatgaac caactgcaag accagcaagg
    23641 ttatcgaatt ttgagaagaa ctcaatggtt ttatcgattg tttcgattgg agttgttgtt
    23701 ggaaattgtg ttttttctac aacgttaaag ttttcatcac cgacagcaca gacaaacttt
    23761 gtaccgcccg cttccaagct tccatataat tttgtcatga taaacctctt gtttttattt
    23821 tctttattat agcatacttc gaaagtctaa atgtctctat tttttagatt ttcctctgta
    23881 aatcttacta tctaataaaa acgaacaaat atgtcatttg ttcgttttca cattagagag
    23941 gattgattag attttcactt cgatcacagc atccccctta gcaactgaac ctgttgcgac
    24001 tggagctact gaagcgtagt cacctgtatt tgtaacgata accattgttg tatcatcaag
    24061 tccagctgca gcgattttgt ttgagtcaaa tgttccaaga acatcgccaa ctttcacctt
    24121 atcaccttga gcaacttttg tttcaaaacc gtcaccgttc atagatacag tatcaatacc
    24181 aacatgaatc aaaacttcag caccatttct tgttttcaaa ccaaaagcgt gccctgttgg
    24241 aaaggcaatt gaaacttcag catcagctgg tgcatagacc acgccttggc ttggtttcac
    24301 agcgatacct tgtcccatag ctccacttga gaagactggg tcattgacat cagcaagagc
    24361 gacaacatca ccgacgatag gagttacaag tgtttcattt tgaagagctg ctggcgcaac
    24421 ttcttctttt tcttcagcca cttcagcttg ttttgcagct gcagttgcgt ctacttcatc
    24481 ttcgtaacca aacatgtaag taagagcaaa accaagggca aatgatacag ctaccataag
    24541 aaggtattgt ggaagttgtc cgttaccaac ataaagcatt gtaccaggga tgatggtgat
    24601 accattacca gtaccagcaa gtccaaggat agaagccaat ccaccaccga ttgcaccagc
    24661 aatcaatgaa aggaagaatg gtttacggaa gcgcaagttc accccgaaga tagcaggctc
    24721 tgtaatacct aggaaggcag aaagagcagc cgggaaagca agtgttttca gttttggatt
    24781 ttttgtttta acaccaaccg caacagtagc agcaccttga gctgtcatag cagctgtgat
    24841 gatagcgttg aatgggttag catggtcagc agcaagtaat tgcacttcaa gcaagttgaa
    24901 gatgtggtgc acacctgaca cgacgatcaa ttggtgaacc ccaccaatca agaaaccacc
    24961 aaggccaaat ggcatgctaa gaatcgcttt tgtagcaata aggatgtagt tttcaacaac
    25021 gtggaaaact ggtccaatga taaagagtcc aaggatagac atgaccaaaa gtgtcacgaa
    25081 tggtgttacc aagaggtcaa tgacatctgg aacaaccttg cggacagctt tttcaaattt
    25141 agctccgaca accccgatga tgaaggctgg aagaacggaa ccttgcaaac caacaacagg
    25201 gatgaaacca aagaagttca tcgctgttac ttcaccacct tgagcaactg cccaagcgtt
    25261 tggaagtgag ccagagacaa gcatcatacc aagaacgata ccaacggcag gatttccacc
    25321 aaatacacgg aaggttgacc acacaaccaa acctggcaag atgatgaagg ctgtatctgt
    25381 caagatttgt gtgtaagttg caaagtcacc tggaagtggc atttcaagag cgttgaaaag
    25441 accacgcaca cccatgaaga gacctgtcgc tacgataact gggatgattg gaacgaaaac
    25501 atcaccaaaa gtacggatag cacgttggaa ccagttccct tgtttagcaa cttctgcttt
    25561 catgtcatcc ttagatgatg ttggtaagcc aagtacaaca acttcatcgt acattttgtt
    25621 aactgtacct gtaccaaaga taatttggta ttgccctgag ttaaagaaag caccttgaac
    25681 tttttccaag ttctcaatca cttctttatt gattttctct tcatctttga ccatgacacg
    25741 tagacgagtc gcacagtggg caacactatt gacattttca cgtccgccca aggcatcgat
    25801 gacttttttt gcaatttcct gattgttcat ttgcaaaaat ctccttatat aacattttgt
    25861 tcttgtttga aagcgatttt attcgccctt acgactatta ttttatcatg ttttaaaaat
    25921 atgtcaagcg ttttgcagaa aaatattcta tccacttagt gggcaagctt tagattgatt
    25981 gtttttgact gtttcatcag gaattccttg aaaaataagt ttgaaacctt gg
//
LOCUS       DAVKEV010000030        25794 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVKEV010000030 DAVKEV010000000
VERSION     DAVKEV010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25794
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.030"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            147..311
                     /locus_tag="VWZ68_001368"
     CDS             147..311
                     /locus_tag="VWZ68_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU9372388.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            395..961
                     /gene="amaP"
                     /locus_tag="VWZ68_001369"
     CDS             395..961
                     /gene="amaP"
                     /locus_tag="VWZ68_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEU9372389.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            973..1143
                     /locus_tag="VWZ68_001370"
     CDS             973..1143
                     /locus_tag="VWZ68_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEU9372390.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1182..1790
                     /locus_tag="VWZ68_001371"
     CDS             1182..1790
                     /locus_tag="VWZ68_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU9372391.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1821..2024
                     /locus_tag="VWZ68_001372"
     CDS             1821..2024
                     /locus_tag="VWZ68_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU9372392.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2119..2397)
                     /locus_tag="VWZ68_001373"
                     /pseudo
     CDS             complement(2119..2397)
                     /locus_tag="VWZ68_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2595..2882
                     /locus_tag="VWZ68_001374"
     CDS             2595..2882
                     /locus_tag="VWZ68_001374"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU9372393.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3160..3930)
                     /locus_tag="VWZ68_001375"
     CDS             complement(3160..3930)
                     /locus_tag="VWZ68_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEU9372394.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3945..4793)
                     /locus_tag="VWZ68_001376"
     CDS             complement(3945..4793)
                     /locus_tag="VWZ68_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEU9372395.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4790..6265)
                     /locus_tag="VWZ68_001377"
     CDS             complement(4790..6265)
                     /locus_tag="VWZ68_001377"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEU9372396.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6588..7943)
                     /locus_tag="VWZ68_001378"
     CDS             complement(6588..7943)
                     /locus_tag="VWZ68_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9372397.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7953..8270)
                     /locus_tag="VWZ68_001379"
     CDS             complement(7953..8270)
                     /locus_tag="VWZ68_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9372398.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEKTSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8287..8604)
                     /locus_tag="VWZ68_001380"
     CDS             complement(8287..8604)
                     /locus_tag="VWZ68_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9372399.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8617..10302)
                     /locus_tag="VWZ68_001381"
     CDS             complement(8617..10302)
                     /locus_tag="VWZ68_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HEU9372400.1"
                     /translation="MKNKKLILSLFILFLLIFIHAKVFANENLIKNSNFEQGELFWNS
                     RNRGIINSNESYSNGHYSGMIPSTAINDNRADGYIGQVIDIEPNEDYLVSAFAKVDIS
                     GAEGYFTARWFDNNKQGEIVQNNIGEAVDQTVNTTEWKKYMFSFNSGKHDKVLIQLVK
                     WSEDDTTKKSNIFIDNVEMYQLSKGNSYKKIWRDDFDGEQLNKKYWGYELGSIRGWEQ
                     QHYVRSDENVFLRSGNLVLRATNRSKEDQYFNPRNNHRKVVYNSGSVRTHGKVEFLYG
                     KLEMRAKLPKGQGVFPAFWTLGSDFTLDGKINPVQGRGWPSTGEIDIMELVGERNSNG
                     SGNKTVYQTLHYGQSDNDDGKFAGRGTAFKLSSGNFNDSYHTFSIDWYKDYIVWMVDN
                     HIVRKVYYGSDNIAKKIFNRPQYVQLNLAMGGSWPGVVDNNLSGTEFVVDYVSYSRND
                     LQQHQAEEYYSQSPKINGAKDIVINRGDVPDLLKGITTNSGYELDYSIENEPMFNNFG
                     GNTSVDLLIRNKTEKEKISQMPPGVYNLHYTSRPKHLDYESKVDRKTVTLTIK"
     gene            complement(10307..11203)
                     /locus_tag="VWZ68_001382"
     CDS             complement(10307..11203)
                     /locus_tag="VWZ68_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEU9372401.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNQEIIKAVQSAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(11206..12468)
                     /locus_tag="VWZ68_001383"
     CDS             complement(11206..12468)
                     /locus_tag="VWZ68_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9372402.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            12748..13926
                     /locus_tag="VWZ68_001384"
     CDS             12748..13926
                     /locus_tag="VWZ68_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU9372403.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(14154..14600)
                     /locus_tag="VWZ68_001385"
     CDS             complement(14154..14600)
                     /locus_tag="VWZ68_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9372404.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVQKYSRLKLE"
     gene            14670..15329
                     /locus_tag="VWZ68_001386"
     CDS             14670..15329
                     /locus_tag="VWZ68_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU9372405.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACGIIFGKLLL
                     V"
     gene            complement(15381..16532)
                     /locus_tag="VWZ68_001387"
     CDS             complement(15381..16532)
                     /locus_tag="VWZ68_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU9372406.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGNRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(16547..17278)
                     /locus_tag="VWZ68_001388"
     CDS             complement(16547..17278)
                     /locus_tag="VWZ68_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372407.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            17507..17608
                     /locus_tag="VWZ68_001389"
                     /pseudo
     CDS             17507..17608
                     /locus_tag="VWZ68_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(17580..18356)
                     /locus_tag="VWZ68_001390"
     CDS             complement(17580..18356)
                     /locus_tag="VWZ68_001390"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEU9372408.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLGETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(18349..19572)
                     /gene="trpB"
                     /locus_tag="VWZ68_001391"
     CDS             complement(18349..19572)
                     /gene="trpB"
                     /locus_tag="VWZ68_001391"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU9372409.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGCPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(19550..20149)
                     /locus_tag="VWZ68_001392"
     CDS             complement(19550..20149)
                     /locus_tag="VWZ68_001392"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEU9372410.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     YFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(20136..20903)
                     /gene="trpC"
                     /locus_tag="VWZ68_001393"
     CDS             complement(20136..20903)
                     /gene="trpC"
                     /locus_tag="VWZ68_001393"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEU9372411.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(20900..21904)
                     /gene="trpD"
                     /locus_tag="VWZ68_001394"
     CDS             complement(20900..21904)
                     /gene="trpD"
                     /locus_tag="VWZ68_001394"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEU9372412.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIITGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(21915..22481)
                     /locus_tag="VWZ68_001395"
     CDS             complement(21915..22481)
                     /locus_tag="VWZ68_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEU9372413.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQTIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            complement(22478..23839)
                     /gene="trpE"
                     /locus_tag="VWZ68_001396"
     CDS             complement(22478..23839)
                     /gene="trpE"
                     /locus_tag="VWZ68_001396"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEU9372414.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEELEKALNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPQKFEEMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(24760..25761)
                     /locus_tag="VWZ68_001397"
     CDS             complement(24760..25761)
                     /locus_tag="VWZ68_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9372415.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
BASE COUNT         8108 a         5497 c         4131 g         8058 t
ORIGIN      
        1 tatattaaag ttatataata gtattaatca aagaaattga ttttttgata ttaaaataaa
       61 aaaggagggt aggcagtgtt gtgatcaatt attgctggag gtcttattgg tctcttggca
      121 ggtaaaatca ctaaaaaagt agttctatgg gaatcatcgc aaatgtattc gctggtttag
      181 tcggggcata tgcaggacaa tctcttttag gtagttgggg tccatcaatc gctggaatgg
      241 ctttgctccc atctattgta ggtgcagcga ttgtgattac tgtagtgtca ttctttacag
      301 gtagaaagta aacttttcgc cagtaaagtt agcaaactat ttttaaatca atgacgggaa
      361 aaatagttta aatgttaaat cgaaaggatt gtatatgtca aaagcaaaga aaatatgttt
      421 cattattttc tgtattttaa tcttgacaat tttccttcct gttttgatag attatcatca
      481 agttagtgat ctaggtattc atctacttag ctggagacag aactccgtag ttgaattcta
      541 tcttgctaga tatgtctttt gggggacagt ggttctatca actttagttt tattatccat
      601 tttagttgtg atgttttatc ctaaacgtta cttggaaatc caacttgaaa ctaaaaacga
      661 tacattaaaa ttaaagaatt cggcaatcga aggttttgtt agaagtttgg tgagtgatca
      721 tagattgatc aagaacccaa ctgttcatgt aaatttacga aaaaataaat gtttcgttca
      781 tgtagaaggt aaaattcttc cttcagacaa catcgctgac agatgccaaa taattcaaaa
      841 tgaaataact aatggattga agcagttttt tggtattgag cgtcaagtaa aacttgaagt
      901 tgcagtaaaa aattaccaac caaaacctca aaacaaaaag actgttagtc gtgtgaagta
      961 aggaagtaaa aaatggaatg gcttaaacaa tatcgatatc caattatcgc tggtctcata
     1021 ggcgtatttc tggcttgttt gattgtctcc tttggcttct tcaaaacaat atttgtattg
     1081 attttaggag cactgggagt tgcagctgga ttatatatcg aaaaaaacta tatagataaa
     1141 taaaaaaata aaaattacta atttaattaa aggagtttca tatgtcaaac gaaaaaaaca
     1201 caaacactaa cgtagaaaag aaagatgcta ctgttgtagc tcacgaaatc aaaggggaac
     1261 ttacttacga agataaagtt atccaaaaaa tcattggtct ttcactagaa aacgtttcag
     1321 gtcttttggg aatcgatggt ggtttcttct caaatcttaa agaaaaaatc gttaacagcg
     1381 atgacgtaac aagtggtgtt aacgtagaag ttggtaaaac acaagttgca gttgacttaa
     1441 acgttattgt tgagtaccaa aaaaatgttc cagctttata ttcagaaatc agagaaatcg
     1501 tatcttcaga agttgctaaa atgactgact tggaaattgt tgaaatcaac gtaaacgttg
     1561 tcgacatcaa aactaaagaa cagcatgaag cagactcagt aagccttcaa gatcgcgtat
     1621 ctgacgttgc tgaatcaaca ggagaattca cttcagaaca attcgaaaaa gctaaatctg
     1681 gtcttggatc tggtttctca actgttcaag aaaaagttag cgaaggtgta gaagctgtta
     1741 aaggtgcagc aaatggtgta gtatctcacg aaaacactcg tgtaaactaa gataaaataa
     1801 atataacagg agaaattatc atgtcagtag aagaaaaatt aaatcaagct aaaggttcta
     1861 ttaaagaagg tgttgggaaa gccatcggtg atgaaaaaat ggaaaaagaa ggagcagctg
     1921 aaaaagttgt ttctaaagta aaagaagttg ccgaagacgc taaagacgct gtagaaggtg
     1981 ctgtagaagg tgttaaaaac atgttgagtg gcgacgataa ataaggttaa aagttacttt
     2041 atctttttgg taacattagt caagatgatt ctcagaaaac aaaaagctag agattcccaa
     2101 ttgcggaacc ctagcttttt aattttgcct ctttctctta ttatatttca gcaggttgtt
     2161 ggccatgagt acgaatccca tgtcaattct cacttgacgc ttccctctca gatgacatct
     2221 cttataaccc aaacaaacct ttatctgccc aaagacagat ttcatatcaa tcttacgttt
     2281 agcgaaaatt tgtctaccct tggaagataa aagtgcctga tattctttag tttttaaaca
     2341 ctggtaacgt tcattcatat acagtccctt ttgaggggct gattcaggtt cataatcgca
     2401 gtcaacattg atttcaaggc tgtttgcttt ctatctcccc tttttcatga tatattttcg
     2461 tacaggtgct tcaatagttt ctatagtaaa atgaaccaaa aatagtacac gttgcggtat
     2521 aatgttcttg tggcatattc attagatttt cgtaaaaagt tctctcctat ttgtgagcga
     2581 acaggtatag tcaattgatt gtcagtttga agaccaagag tcgtaaggca aaggatatgg
     2641 cagaatccat ccaagggtgg ctggcacaat ttctagtgaa cctctttaaa tctattacgt
     2701 ttgactgtgg aaaagagttt tcaaaatgga aagatatttc caatcatcac gatagtgaga
     2761 gcttttttgc gaatctagga tgtccaagac agcggtgtct caacgaacat tcaaatagac
     2821 ttttaaggtg tcatgacttg ccaaagcaga cagatttcaa cgaagtcagt caagaatttt
     2881 aggctgggta aaaactcaat ttcaggagaa aatgaaataa atattcccac aataaaatgc
     2941 atagtatcaa agtttttcca acacctgata ttatgcattt tttaatttta aagacttttt
     3001 cccagcctca agaaatcaca tcccacctaa atcctttgga taccaaatac ctcatcaggt
     3061 attttctgag ttggtaagac tgtctagctt aatttgacaa atggagggcg ttaaatccag
     3121 tttttacagg aagtctattt aaatattttc acactgacct tacaaaatat gaaacaaatt
     3181 atataaagtc attcccatga caaagaataa catcccttta aaacagtatc ttacccaatt
     3241 ttcaggtaag acttttgata caaccgtccc caatacccct ccgcatatag aagcaagaaa
     3301 aataactgga acaggtgcta aatgatactg atttaaacct gtaaccacaa caattgtagc
     3361 caaatgagac agctgggaaa agaaaataat tgcaagagaa tacatcgttg cttcttttat
     3421 cgaaatagaa aaaaacacca tcaataaaga tacattgagc ggaccaccac caatccctaa
     3481 aaaactagaa attaagccca atagaagacc acaaatcata tagaatccta tcttatcaaa
     3541 ttgataagtt tttttaaaat ctgttaaaac aaatgataca agtagcatca caaatagtaa
     3601 aatcatttga acaatggata ctagccgtac tgataattga gataacaaaa cttgaaaaat
     3661 aagatgacct agaaatcctc ctaaaacaga agaaaaggat accgtaaaaa tcaatctcca
     3721 ttttatctct ttactttgtg aaaatctttt gattgttgaa ataatcgcca ttataaaaac
     3781 agagaaacta gaataaaaag caatatcact gaccgaatgg tatccaaaac tatccataag
     3841 tggcttaatt ataattccac cacccatgcc tgatatagaa cccaatccac tagctattat
     3901 aatgattaga aaataaataa tctcaaccac tttttaagtc catcctattc tttcaaacat
     3961 ctaaaaccta gatggctact agtggaagta gaaatacatc catttctagc agctactcgg
     4021 tatcgattac aataagaaca atgacataaa aaggaacctc ctctgatagc atactcctca
     4081 tcttgtatcc catattttgg caactcatag tcatcttcat taaaactagc taataaggta
     4141 tatctcggat tgcgacacca ttcccaaaca ttcccaatca tttgatatag accaaaatca
     4201 ttaggtaaaa attcatagac aggagccgtt cctataaatc catctaaggc agtattttca
     4261 taaggaaatc ttccttgcca agtattggca tgataatatc caccttctaa aagagtatct
     4321 ccccaaggat attcagattg tcttcctcct ctagcagcat attcccactg tgcttcagtc
     4381 ggtaaagaca ttccgctcca attacagaaa gccaatgcat cttctaaagc aacatgaact
     4441 actggatggt cttctaaacc cactagatta ctattctcac cgtagggatg tttccagcaa
     4501 gcgttcggaa cttgtaacca ccacggagcc ccagcaggat gaggatatcc ctccctttct
     4561 gcctctggaa cgaacaatat aaaaacaaaa gaccactctt gtcgctcagc tagtgtttta
     4621 tagcctgttt ctttcacaaa ttgagcaaat tcttgattcg taactggagt atccgcaatg
     4681 gaaaaatcct ttacactaac agcgacttga ggaccttcaa aatcatctaa aaagccctct
     4741 tcagaatttg ttcccatcat aaatgtccca cccttgattt ttttcatttt catgattgac
     4801 tatcccccgt tttcgttaga gttggcgtta ttttagaaag ttcaacagga actaactctt
     4861 catccacaac aaaaccttct tctctatatc taagaaagtc tactaatttt ttcttcatct
     4921 gacgaacaat aggttgatat ttttcacttg gatacaaatc attcatttca tgcggatctt
     4981 ttttcatatc aaataactga taatgattta aaacaggaaa ccagataaat ttccactggt
     5041 ctgtcaaaat atattgacta gaatcttttc ctaaagcatg ttcaccatga aattctgttc
     5101 gccacccctc gtactgtcca aataataaat tcttaacact ccgtccatct agttcatctg
     5161 tagtagttcc tcctgccaaa tccacgagtg aaggaaaaat atcttgaatt ttcactaatt
     5221 gcttgattgt tcccctatta ccagctatca atccagccgg atcgtaaata aacgaaggaa
     5281 tgtggatact tccctgataa ggatatccct ttctaaacag ataatgttca ccaagctgat
     5341 ctccatgatc cgaaacaaac cagataatcg tatctttatc atgacgaaat tcttttaggg
     5401 cagtcaaaaa gcgactaatt tgatggtcta tatgagtaat caatccaaaa taagcagcaa
     5461 ccattcttct ttgatcatct tcctttaatt tccctcttaa agcataaata gacggaattt
     5521 gcttttctaa tacttcccaa ttcccgatat gcaaatcgag aaattgaggc aagcgttcca
     5581 tatacatatc aaaatagtat tttgggggat ttaatggagc atgtggtttt tcaaaagaca
     5641 ttttgagaaa aaaaggaacc gttggatctc ttctttgtaa aaatgaaatg gactcactca
     5701 caacccagtt tgttggatgt aacttctcat ctttatccca aggtctagct tcccaagaat
     5761 tacaatccat tccgtcatca atcaaatcaa catcataacc aactttaccc tttaaaaagg
     5821 ctagatagtc actagcataa tcaaattgac ttccataagc cttatcatac tttctatcaa
     5881 catgtagata cccatcgtga agtaagacat gatcaaaccc aagtctctgt ctggaaggaa
     5941 aaacatgcat cttaccaata cactctgttt gataacccat atctttaaag acttttggaa
     6001 gagtattagt aaaattccaa ggcacctcat cttgataacc aactcgtcca cttttatctt
     6061 ggtctaagcc agtcaataaa gctgccctag caggaacgca agaaggaact ggagaatagg
     6121 cattttcaaa attataacct acactagcca tcatatctaa tgttggagtg ctaactagct
     6181 tatccttact attcaaggat aaggcgtctg ctctcatttg atctacaaca atcaaaataa
     6241 tatttggctg ttttgtctga accataaaat ctcctttcta atatggcaaa agaggcacaa
     6301 gaagatatct acctttactg cacccctttc tatatcaatc tctctatata aaacaataac
     6361 attcttgtta tgttttatag aaaaatgaac taaaatatga ctaaatcgat taggaaattc
     6421 aaatcatttt ctagtactgt tttagaagtt acagtgtact attccaactt caataaacta
     6481 taaacctttg tctaataaca attttagtgg agataagaaa tcctacacct aactcatctt
     6541 acacgtaatc tatttctatt ttatcacaaa aaacgcaagt aagaccatta actcaattca
     6601 gttttatctg ccattttcac aaatgggaaa taagtcaaga cactaataat caaacaaaca
     6661 actgataaga tgatggcacg ccaatcaaat gctgtagaga agaaaccata taaaattgga
     6721 ggcattaccc aagtaacgtt ttgtgtaaca ggtgaaacaa gaccccagct tgttgcccag
     6781 taagctaccg ttgccatgaa aaccgggcta agtacaaatg gtataaatag caaaggattc
     6841 aagacaactg gtaaaccata attgaccggc tcaccaatat taaacagaac tggtgctaga
     6901 ccaagtttag caacttttcg ataatgactg tttcttgaaa aaattaaaat agcaagtact
     6961 aatcctaatc ctccaaacca gacaaacgcc ccaaaagacc cacttgtcca tatataagga
     7021 atcggttcac ctttttggaa agcatccaga ttcgctaaca tagcaactcc aaacagccct
     7081 tccatgatgg gagccaatac atttcctcca tggagaccaa aaaaccagaa taacttattc
     7141 aaaaagatca tcagaataac tgcaaagaaa ctttgagaca aacctagtaa tggcgtttgt
     7201 aacaccttgt aaacccaatc aatcaataag tcattgctaa gtaaatggaa aacataagtc
     7261 aagatggcta ctatatacat cgccataaat cctggaatga tagaagtgaa cggcttagca
     7321 atcgcagggg gaactgaatc tggtaacttg attacccagt tctttttcat tactttacag
     7381 aaaataatag aggctaaaaa tccaatcatc atggctgtaa agtagcctct ggcattaata
     7441 tggtttcctg gaatcacatt cccaatagtt accatcagat ttttaccatc aaatgctaga
     7501 ttatcaattc cttgtaagat ttgatctaat ttcacatctc ctacatttgc caaagggaaa
     7561 ctctttgtaa ctgtacttcc aatcgaaatg acaaacgaag caagtgatac caaaccagca
     7621 gaaactgtat caaccttgta aatcttagcg atattcactc ccaagcaata gatgaacaac
     7681 aaggaaacaa ttggtatact tcccttgaat accaaattat tgatgtcaac aagccactga
     7741 aaggttttcg taatactttc taggtgaaat tgttgtggta aatccactag aaaagcattt
     7801 aataacaaag caatggaacc tgtcataata acaggcatag tccccacaaa tgaatcacgt
     7861 aaagcaacta aaaacttctg attcccaact ttcattgcaa ttggagaaag tttttcttgc
     7921 attttatcca acattgtatt cataccaaac tcctaatttt tttcaaatcg ttcgtatact
     7981 tctaccactt ctttcgccaa gtcaacaaaa gtcagactcg tcattaaatg atcttgcgcg
     8041 tgtaccatca agaggctaat tgatgttttt tccccctgtg cctctcttgt caacatttct
     8101 gtttgagcct tatgcgcctg taataaggca gcattcgcat cagctaatct tcgattggct
     8161 ttagagaaat cccctttttt tgctgcctga atagcctcca tagcattact tttggcttcc
     8221 ccaccataca taattagccc cattacagat tctaaattac tttcatccat aacattctcc
     8281 tcaatcttag tctaataaac tttcagctaa atctaaaact ttagaaccat tcatcattcc
     8341 gtaatctgtc atcggaataa ccgccacagg aatctgtcta tcttttagtt tttcttgaaa
     8401 gtcccctagt aaatagcgaa cttgaggacc taaaagcaac acatttactt cttttgttgc
     8461 tacaatttct tctgcttcag gagctggaac tgcaaaaatt tctgcatcca accccttatc
     8521 ttctgctgcc ttttgcatct ttgtcactag cagacttgta ctcatacctg ctgcacatgc
     8581 taacataatt gttactttag ccatagctta ctccttttat tttattgtca atgttactgt
     8641 ttttcgatca actttagact cataatctaa atgtttggga cgactagtat aatgcaaatt
     8701 ataaactcct ggaggcattt gtgaaatctt ttctttttca gttttattgc gaattaataa
     8761 atctaccgaa gtattccctc caaagttatt aaacataggt tcattttcaa tagaataatc
     8821 taactcatat ccactattag ttgtaattcc ttttaataaa tcaggaacat ctcctctgtt
     8881 tattactata tccttagcgc catttatttt gggagattga ctataatact cttcagcttg
     8941 atgttgttgt aaatcatttc tagagtaaga aacataatca actacaaatt cagtccctga
     9001 taaattattg tccactaccc caggccaact tcctcccatc gctaaattta actgaacata
     9061 ctgaggtcta ttaaaaatct ttttcgctat attatctgat ccataatata cttttctaac
     9121 aatatgattg tcaaccatcc atacaatata atctttatac caatcaattg aaaaagtatg
     9181 atacgaatca ttaaagtttc cactcgataa tttaaaggct gtaccacgtc ctgcaaattt
     9241 tccatcatca ttatccgact gtccataatg aagcgtttga taaactgtct tattcccact
     9301 tccatttgaa tttcgttcac caactaattc cattatatct atctcacctg ttgacggcca
     9361 tcctcgtccc tgaacaggat taatcttccc atcaagtgta aaatccgatc caagagtcca
     9421 gaaagcagga aaaactcctt gacctttcgg taattttgca cgcatctcta atttaccata
     9481 aagaaattct actttcccat gtgttctaac acttcctgaa ttatatacaa cctttctgtg
     9541 attgtttctt gggttaaaat actgatcttc cttagagcga ttcgtagctc taagaactaa
     9601 atttcccgaa cgtagaaaaa cattctcatc acttcttaca taatgttgct gttcccaacc
     9661 acgaattgat cctaattcat atccccaata ttttttattt aattgttcgc catcaaaatc
     9721 atctctccaa attttcttat atgaatttcc tttagacagt tgatacatct ctacattatc
     9781 aataaaaata ttagattttt ttgtagtatc gtcttctgac catttcacta attgaatcaa
     9841 aactttatcg tgtttaccgg aattgaaaga aaacatgtat tttttccatt cggttgtatt
     9901 aactgtttga tcaacagctt ctccaatgtt attttgaaca atctctcctt gcttattatt
     9961 atcaaaccat cttgcggtaa aatatccctc tgctccacta atatctactt tggcaaaagc
    10021 agatactaaa taatcttcat taggttctat atcaataact tgtccaatat atccatctgc
    10081 tctattatca ttaattgcag tagaaggaat catacctgag taatgtccgt tactataact
    10141 ctcatttgaa ttaattattc ccctatttct agagttccaa aacagctctc cttgctcaaa
    10201 atttgaattt tttattaaat tttcattagc aaaaactttc gcatgaataa atattaataa
    10261 aaataatata aataaactta aaattaattt cttattcttc attttatcac ctatttactg
    10321 acctagccaa gcgagatact gtatgtctca ctcctctaat tgccttgctc aatgcataaa
    10381 tattatcgac tgttgccagt cccccatatc ctgcgtcacc tatatgttga atatcaactc
    10441 cacaaatttt atttctaagt gcaatttcct tgatagtatc tgtatcagat gtttcttggc
    10501 tagtaccaat agcactcaat acaagaccac ccttactatg aacgagatca acgacttcac
    10561 gcaactcttg gtcatgaaag gctggaacgg ttccaactgc tggaacaagt atcacatccg
    10621 cacctgcttc caacaattgc tctgcgacag aaagctctgc cacaggctca ttcactcctg
    10681 ccccgtgcat tttaccagct ataatcaaac ctgagaaatt ctctttagca gattgaactg
    10741 ctttgataat ctcttgattg ctaactcctg ttccaggatt tccagtcaaa cagacaaagt
    10801 caaaacctaa ctcctctatt cgattcaatg tttcaacact agcaacacga cctgcaacaa
    10861 tttcctgtgt ttcctctagc atctttgcag atgggtcaat cggttccaaa tttacaccaa
    10921 ttggacaagc aacaagctgg tgtaagcgat gaataacatc atcacctgaa ctatccaaag
    10981 cataaatttt aggctcaaaa acatcaacac aattcaataa aatcatatca gctccaaaag
    11041 ctctagcaat ttcagaatta gttatatccc caacaaatgt ctcacgagta actacatttt
    11101 cagatagaac aactctacct tcacttgcta aaatactttg ttttaattct tcagcattca
    11161 tctgtaatat ctcagatgga tttgcactaa ttaaacgttt cattctcaat cctccaataa
    11221 cttaaaccgt ttttcaatag ctattacaaa tggtaaataa agtaagacat ccaaaacaat
    11281 caatacaatt tgtaataatg aaccagaaat acttcctgta gcaagtaaac cacttataac
    11341 aggtggcata gtccaacctg gatctgtata agttagcgga accaaacctg atgccattgc
    11401 tccccacgct actagtaagt taaacattgg agctaagata aatggaacta gtaacaaaat
    11461 gttcaaaaca ataggaacgc caaacattgc tggttcattt atattaaata atccaggtat
    11521 aacagttata ggtgccaaag tttttagttg tttactagct ttcttcttat gtgctaaata
    11581 tcctaacgca agaactaaac ctatggttgc accaccgcca cctatgaata caaaattatc
    11641 cataaatacg ctagtaaaaa tatttggaag agtttctcca gtttgataag ctactttatt
    11701 tgcatctaga ttagctaacc ataacggttt cataactgca ttaacaacat ttcctccgtg
    11761 taatcctaca aaccaaaaac tactattaag gaaaattaag ataagaagac caataacatt
    11821 atttcctaaa agtccaagtg gacctcccaa agctacttga gcaatttcat gaagattagg
    11881 taaacttaat ttatctaaag ttgcataaac aatcaaccaa ccaacaatag tcactgcacc
    11941 aggaataatg gcactaaagc ttttagatac tgctggtgga acaccatccg gcatttttat
    12001 ctgtatatta tgatttataa accattggta gatatagcca ttaatcaatc ctaaaatcat
    12061 agcaacaaat aaaccttttg atgccatgaa agcggtaggc attcctgctc cagcctctcc
    12121 tctaatgaaa ggcgtaactg taataaaaga tgataatgac acaataccag caggaatacc
    12181 atcaactttg tattgtctag ccataaagta agcgatacca aaactagcta caagaccaag
    12241 taatccaaaa ctactatcaa cacccttcca taaatagtca gcaacaccaa tatcacccag
    12301 atatttttcc catcctggaa taggaaaact tgcaataacc attagtaatg aacctatcaa
    12361 caataaaggt atagttagag taataccgtc tcgaatagaa accaacgctt tattattacc
    12421 caatctagcc gctactggaa gtaacttttc ttgtaataat ttttccataa ccttttcctc
    12481 ttaaatatat tttattatca aaagttatca attatcttta ttttttgacg tcaagttgtt
    12541 atttgattat cttttgttat ttatatttta caactataag aaagccttgt caaggatttg
    12601 tgtaaacatt tgattatttt ttattatcaa tatataataa aaagagacca gtaagtaatg
    12661 aaaagcttaa aaaaattaac atctacattt atccatagca aaaaatcata ggattttaag
    12721 aatctgacaa ctaggaagaa aactaatatg accttatcta agaaacaatt acaactaaga
    12781 gctaaaatac tggaaacagt ttacacatta ggtcccattt cacgaattga aatcgctact
    12841 aaaacaggaa taacacctgc aacaactagc agtatcacaa atgatctgat taaagaaaat
    12901 attctcttag aacttggtga agacgaacac gatacaagcg tagggagaaa aaaaatcctg
    12961 ctagacattc aagctaaacg attttactac attggttgtg aactatctga aaaacatttc
    13021 acttttgctt taggagataa tctaggaaat atcttaaagg aagagaaaga aattgttact
    13081 aaacagttaa tccaagaaaa gggaaatcaa ctcattaacc agacactaaa gcaattctta
    13141 aataactgct ctgattatga aatagaagca attggaatcg cgctacctgg tcgctattta
    13201 gataattata aaataacaac aaacaatcct ttatggcaac atatcgactt agaaatgatt
    13261 caatcccact ttgataagcc tttgtttttc tctaacaatg ttaactgtat ggctataggt
    13321 aaacgcctat ttagtcgcca acagaatgac cctaattttg cttattttca ttttgctaga
    13381 ggtatgcact gttcttatat ctacgacgga aacatttatg ggaaaggaaa tctaatgatt
    13441 ggagaaatag ggcatacagt tgtttcatct gagggagaag aatgtagctg cgggcgcaag
    13501 ggatgcttac aaacttttgc tggagaatct tggttaatca aaaaatcaaa aattctatat
    13561 catcaatctc cctattctct acttcctagt ttagtcaaaa atgccgatga tattgatatc
    13621 caagttattt taactgctta tcaattaggt gacactggaa taatcacact tatccatcaa
    13681 gccttactct atcttagtca aaccatttta aatatcagta tgatgattga ctctcaaaaa
    13741 atctacctac atagtccttt actaacaaat caacacatca tccaaaaact atatagtgaa
    13801 atgaactaca aacccaaact gctctataat cgcctacctg aagtcattat tgaaccttac
    13861 aatgatttta cagccgcaca ctcagctatt gcactttgtt tgtatcatac aattctacat
    13921 tcttaatttt ctattacatt taataaatag gctaaaaaga gggagtatat cataaaaagc
    13981 gaataaacct gttttctgaa aatcagaatt ctgttttgtt cgctttcttt atatttggaa
    14041 ttatactcct atctcccctt tttcataatg tatagtaaaa tgaaataata acaggacgaa
    14101 tcgatcggga cagtcaaatc gatttctaac aatgttttag aagtagaggt gtactattct
    14161 agtttcaatc tactatattt ttgtacaggt gcttcaacca tttgaacgat ttcaaatcct
    14221 tctttttggt aaagattctg agctctttga tttgcctcga agacatttag agaaatacta
    14281 tctatatctt cattttcaaa ggccaaacta acaaatttcc ttaaagcctg gctacctaag
    14341 tcttgctcct gtttctgggg gttgataaaa aatctcccga tatgaagatt gctgtcttct
    14401 agcctgattt tctggataag tcccacaaac tcttgttcat caaagattga aaagactcct
    14461 tccaaggctt gaagggtcag tagaaaagga atccttggtc ccatccattg ttcttgaaag
    14521 gatttgccta gggagttgga ccactggcat acaaattgag cgttttctat actcaccttt
    14581 tcttcaaaac gaattgtcat cttttcctca ccatcttatc tatgtttctc cattatacta
    14641 tttctcccat tttttacgaa tagataagta tgattgattt ttattttttt ctcgtcggga
    14701 gcattctcgc ttcctttctt ggtttggtca ttgaccgttt tccagagcaa tccattatca
    14761 gttcagccag tcactgcgat tcctgtcaga ctcgcttgcg tcccttagat ttgattccga
    14821 ttctctcaca ggtcttcaat cgctttcgct gtcgctactg caaagttcgc tatcctgtct
    14881 ggtatgccct ctttgaatta gtcttaggac tcctctttct gctttactct tgggaattgc
    14941 tttccttggg gcaagtcgtc ctaatcaccg ctggtttgac cttgggtatc tacgactttc
    15001 accatcagga atatccctta ctggtctgga tgactttcca cctaatccta atagcttcct
    15061 ctggctggaa tctggtcatg gtctccttcc ttgctcttgg aattttggct cattttatcg
    15121 atatccgcat gggcgcaggg gatttcctct ttttagcttc ttgtgctctc gtctttagcg
    15181 taacggagtt actgatcttg attcagtttg cttctgcgac gggtatcctg gcctttctcc
    15241 tgcaaaagaa aaaggagaga cttcctttcg tgcctttcct cttacttgct gcttgtggga
    15301 ttatttttgg taagctactg cttgtctgat aaaatccaat ttctgccata tgtccttcat
    15361 gaaattattt cacagttaaa ttataaatta tttcttttgt acaaagggat gatgttatca
    15421 aatcgatctg ttcttctatc ttcttgatac tgatcaaaaa atttcatttc gactgaaaat
    15481 atttcgctta taaactgtaa acgaatactt tgtttagaca ttatagtcgc tagactgact
    15541 agatgattac tcaaaacgac gtccagaata ctctttactt tgcttggttt tttaacaaaa
    15601 atttgatcat ccaaaggttc aatcattttg taaccttttt gcgcaatttg acgataaaag
    15661 taagaatgtt gctttggagt caataatcct aacttaaaag ctcgatactc taaagcctgt
    15721 atcgaaacat tcaaatccga cttcaataaa atataactat caggattgct gacacgcttg
    15781 ccaaccctct cttcaaattt gactaaaaac tcttcttttg gcaataaaaa acatgatgca
    15841 aaataatttg cttcttgctc caaacgattg ccatcttcat tcatatcttt atatttatgt
    15901 aaaagaatat gtcctagctc atgagctaag tcaaaatttc gacgtacaga tgatttattc
    15961 gttcccaaca caatataagg tcttcccaat tttgaccatg cgctataagc atcagcttgg
    16021 ccattaatta atcgttccac gatatagata cctgaacgtt ctaatttata aagcaaatca
    16081 tgattatctt ttgaaatacc taatttttcc ctggcataaa gagccaattc ctcaatggat
    16141 tctcccttat gataagattc actcactaca ttacttaggt catgaattat aatattaggt
    16201 ataattacaa aactttcaaa ataatcaatc aaactatcta ccttatgtaa atacatagtt
    16261 tgaatatcta ttgttttccg tgttgctagg tctgcatttc taaaggcaat tacagaagaa
    16321 tcaaatcgaa tgctctcttc ttcctgttca aaataagtta aatcaacatg aaattggttg
    16381 gccaaatgca ttttggttga taatttaggt ttcgtttcgt tggactcaaa ctgccaaatg
    16441 gcttgttccg ttaaattaat tctctgagct aattctgctc tacttaaacc atttaacagc
    16501 cgtaattctt tcaatacccg accattaaac atttatatac tccttactac ttttgacctt
    16561 cttgtttttc tattcttgga ataatttcaa aatcttctgt ttccgataat tctgaaaaat
    16621 taggaatatc ttgatattta gcttcttcga aatggtacga acttgattga atatactcag
    16681 acaaatcttg aatcaagtgt agctgaccag ttcgtgcatc aggcataaca acatctacag
    16741 atataatatt gttttctgag tccgcctcat aagttaaaat cataaatttt tcgatattcg
    16801 aatttttagt agcttgttca atttcttgaa tcatttcatc agaaactaac tccatctgaa
    16861 ttggaaagga atgactatct tcatcatttt tgtaggaaga atgttgatta agataaagtg
    16921 tattcatctg agcgtattca aataagtagc cactcttatt tttttgtacc aaaggaaatt
    16981 ggttcgtaag tcgcttctta ccctttataa ttaacaatac tttcccatat ttttctgtat
    17041 ttgtttcaaa ttctaaatat ccccaagtct gtcctgctaa ttgtaattta tactcaaaca
    17101 aatctgctga tgcaaatgca gtatcaatat gattaggtcg cgtccatgca taaccattcg
    17161 acactatcat tgtctctctt ttttctagac gttcatctac ataatctttt tgccctttca
    17221 tcaaagtatc tacaattttt tgtgcctcaa gcgaatcaaa gagatcctga ttcaacataa
    17281 ttcttcctcc tccaaatact ttttaatgaa ttatatcatt ttcttaaaga aattactaca
    17341 ataattatct ttttcttaaa gttctgtgtc agagtaattt agaaaattat atcttctata
    17401 gtaaaatcaa ttaaaaactg aacaaattta ttgggaaatt caaatcgctt tctgaaaata
    17461 ttttaggaac cgtagtgtaa tattccagat tcaattcact ataaaactga cctttctcct
    17521 gcaaaagaaa aaggaaagac ttcctttcgt gcctttcctc ttacttgcta cttgtttgat
    17581 tatttttggt aagctactgc ttgtctgata aaatcctgaa tcggctctcc ttggtggaga
    17641 gcttttacta tttttgaacc gacgataaca ccatctgaca ccgcattgaa gcgttccaga
    17701 tcggcttgac tagatacacc aaaacctgtc aagactggga tgtcggccac ttgatgaagt
    17761 tgcgccaagt gcttgtccaa atctgcacgg taattgcctg atttccctgt caccccattg
    17821 atggcaacgg catagacgaa tccctccgcg ccttcaatca actctttctg gcgctcaatt
    17881 cctgtggtca agcttactaa aggaatcaag gcgatatctg tatctgccaa aaatggttct
    17941 acaaagttgg catgttcatg aggcaagtct gggataatca agcccttcac agctgtatca
    18001 gccagatctt tgacaaagtt ctccacaccg tactgaaaga gggggttgaa gtaggtcatg
    18061 atgaccagtg gaatctctgt ttcaatggtt ttcaaggttt caactaaagc ctgggtagag
    18121 gtcccgtggg ctaaactgcg caagccagct tcttcgataa caggtccatc tgcaacaggg
    18181 tctgaaaagg gaatacccac ttcaattgca gagacaccca aatcttctag aaagtggatt
    18241 gtttctccta gtccatccaa acctttctcg tggtctccag ccatgatata gggaacaaaa
    18301 attccttttc cagctgcttt aatagcattt aatttttttg ttagtgtctt aggcatgagc
    18361 ttctcccttc tttgctgcat ctgcttccaa gcggtctttg acttgaacca catccttgtc
    18421 cccacgacct gataggcaga caatcataga cttttctggt ccaagttctt tggccaattt
    18481 caccgcaaag gcgatagcat ggctagattc caaagctggg ataatccctt ccacacgaga
    18541 caagagttgg aatccttcca aagcttcttc gtctgtcaca gggacatagc tggcacgttt
    18601 aatatcgtgg tagtgagaat gctctggacc gataccagga tagtccaaac ctgctgagat
    18661 agagaaggct tcaagaattt gaccatgggc atcttggagc acatccatga gggaaccgtg
    18721 aaggacacct ggacaaccct tggtcaaggt agctgcgtgg tgctccgtat ccacaccaag
    18781 tccagccgct tcagctccat acatggctac tgactcatct tctacaaagg gatggaagag
    18841 accgatggca ttcgacccac caccaacaca ggctactagg gcatctggca gattttgtcc
    18901 tgtcaagtca cggtactgtt gtttagcctc tcgaccaatg acactttgga agtcacgaac
    18961 aatttctgga aatggatgag gccccaaggc agaaccaaga atatagtggg tatcatcgat
    19021 attagccacc catgaacgaa gggctgcatt aaccgcatcc ttgagcacgc gcgaaccatc
    19081 tgtcacggcc tcgaccttag ctcccaaaag ctccattcgg aagacattga gggcttggcg
    19141 tttgacatct tcctcaccca tgtagatggt acattccatg ttaaagaggg ccgcagcagt
    19201 tgcagttgcc acaccgtgct gaccagcacc cgtttctgcg ataattttct ttttacccat
    19261 gcgtttggca agccaaactt gtcctaaggc attgttaatc ttgtgggctc ctgtatggtt
    19321 aaggtcttcc cgtttgagat aaatcttggc tccgccgata tgctgggtca agttttttgc
    19381 gtaataaaga ggagtttcac gtcctacgta ctggcgcaaa agctggttta attcctcttg
    19441 gaaacttggg tctgcctgac tttcacggta ggccttctcc aactccaaaa ctgctgtcat
    19501 caatgtttct gggacaaaac gtccgccgaa ttttccgtaa aatccatctt tatttggttc
    19561 ctgatatgcc atgctttacc ctctctataa atcttctaat cttttcatga tctttttgtc
    19621 catctgtctc cactccgctc gatacatcta ctgcataggg agtaaaatat tgaattgctt
    19681 ttactacatt atcttcatta aggccacctg cgataaagaa gggctgtgct agtccagtcg
    19741 tatccagttg accccaatca aagggctggc cacttcctgc cacaggggca tcaaagagta
    19801 gataatctgc ctgagaatta gggacatgcc catttccatc tacctgcaca gcctgaatac
    19861 tggcacaagg caaattctca aataaatcat ctgccacctg accgtgaact tgaaccaagt
    19921 ccaagccaac tttgtcaatc gcttccagca gttctacccg acttggtgaa acaaatactc
    19981 caaccttttt cacatctgca ggaataagct ttgccaactc agctgcctct tctaaagtca
    20041 cctgtctttt actaggtgca aagacaaaac cgatatagtc ggctcctgct gaaacggctg
    20101 tttccaccgc ttctttggtc gatagtccac aaattttaac ctttgtcaat ctgcaactcc
    20161 ttgattctct gggccacatt ttctgcctgc ataagagctg tccctaccaa aattccgtta
    20221 aagtatgggg ctagtcgttc cgcatcctgc cctgtgaaaa tggcagattc agaaatgtaa
    20281 tagcgacctt cctcaaagta aggggctaaa tctacactgg tctgcaagtc gacctcaaag
    20341 gtagtcaagt tgcggttgtt gaccccgata atctcagcac caagtctgtg ggctacctct
    20401 agttcagcta gattgtgagt ctccactaag acttccagac caagctctgt cgcgtagtca
    20461 tacagttcct tgaggcgttc ttcggacaag gctgccacaa taagcaagat aactgtcgca
    20521 cctgcattgc gagcgcggat gatttgcttt tcatctatga taaagtcttt gttgagcgtc
    20581 ggaatctcta cctgactgga aatttcccgt agataatcca aatgcccttt aaagaaaacc
    20641 tcatctgtca acaccgaaat catcactgct ccgttttctt cataagtctg ggcctgttgc
    20701 acaatatcca catcgagatt gatatctccc aaactagggc tagctttctt gacctcagcg
    20761 attacctgca agcagtcctg atgattcttc aaaaattctg ccaagcgata ggtctggcgc
    20821 agaggctgga tttgctccag cttcatctgc tccacctcac gcgccttctg ctctaagatt
    20881 cgtgctaaaa attcctgact catttttggt actcctgtaa cagtctgagt ttttcaaggg
    20941 ccttgcctct agcaatcact tgacgggcca aggcaactcc ttccttgatg ctatcaatct
    21001 taccattagc atagaaacca agaccagcat tcaagactgt cgtttccaag aatggacttg
    21061 cttcgttttt cagaacgcta agcaaaattt ctgcattttc ctgagcattc cctccacgaa
    21121 tatcttccat agcatagcct tccattccca aatcctctgg agtaaagctt gacaagctga
    21181 tttcgccatt ttcaagaagt gcaatcttgg ttgttccgtt caagccagct tcatccaacc
    21241 cttctggtcc agcaaccacg atggcacgtt tgcgacccat atttttcaaa acctgagctg
    21301 tactttctag gagttctgga cgactaattc caagaagctg tgtttctaaa gccattggat
    21361 gaatcagtgg accagtcaag ttcataatcg ttggaattcc caattccaaa cgagctggca
    21421 tgatgtattt catagctggg tgcatatttt tagcgaagag aaagacgatg ccagttttat
    21481 caaagacctt acctagttca gctggtttga ggtcaagatt gattcccaag gcttcgagga
    21541 catctgcgga accagattta gaagaaatcg agcggttacc atgcttggcc atgtgaatac
    21601 cgccaccagc caagacaaag gctgcagttg tggaaatatt aaaactgaaa gacttgtccc
    21661 cacctgtacc acaattgtcc atggcatcat gaatctcagt tggaatatgc tgggcatgtc
    21721 ctctcatgac ttgggcaatg gctgtgcgtt cttcaggtgt ttcccccttc atcttaagag
    21781 ctaagaggag agaagcaatc tgcgcttcag ttacacgccc agttatgata cgctcaatga
    21841 catccgtcat ttccacacct gataaatttt caaattttgc tagtttttca ataatctctt
    21901 tcatcctagt ttcctcactt tacaacctcc tcgataaaat tccgaataga agacaagccg
    21961 tctggcgttc caatgctctc tggatggtac tggaagccat aaatcggtag gtttttatgt
    22021 tgaatcccca tgatggtttg gtcatcagtc gaacgagctg tcacttcaaa gtcttctggc
    22081 atttcctcaa tcaaaatact gtgataacgc atgaccgcac gtccatcctc aataccttga
    22141 tacaaaacag atggcgcttc aaagttgata ttgctctgtt tcccatgcat gacttttgga
    22201 gccaaaccta gcttaccacc aaagacttct gcaatggctt ggtggcccaa acaaatccct
    22261 agaatcggct tcttgcctgc aaaatcacga atcatgtctt ccatctttcc agcatcaact
    22321 ggccaaccag gaccaggaga aaagaccaga ccatctgctt tttcagcttc ttcatacagc
    22381 ttggaatcat catttctcag aacctgaact tctgcaaaat tcccaatgta ttgggccaag
    22441 ttataggtaa aagaatcata gttgtcaatc aataaaatca tggtcttagt tctccaattc
    22501 tagtcataga ttttgctttg ttaatggttt cttggtattc gttttgggcg atagagtcgt
    22561 agacaatccc tgccccagcc tgcacatagg ctctttgatt tttgagaatc atggttcgga
    22621 tggcgatggc caaatccata tcacccgtcg cagacaagta gccgattgcc ccagcgtata
    22681 ctccccgttt ttccgtttcc agttcataga tacgtctcat cgctcgaatc tttggcgctc
    22741 cagaaacggt tccagcagga agcgttgctt tcaaggcatc catggcagtg agttctgcaa
    22801 gcaaacgtcc cttgaccaca ctggtcaaat gcatgacgta gcggaagagc tccacctcca
    22861 tatacttagt aacttggaca ctggccgttt cagagatgcg gccaatatcg ttacgcccca
    22921 agtctaccaa cattcgatgt tctgctgttt ccttctcatc agagaggagg tcagtcgcca
    22981 aggccttgtc ttcttcatcc gtagcccctc ttggtcgcgt ccctgcaatc ggattggttg
    23041 tcacgatgcc atttttgaca gaaaccaaac tttctggact agctccgatg atttgataat
    23101 ccccaaaatc atagaaataa aggtaattag aaggattagt tacgcggaga tttctgtaga
    23161 agtcaaatgg atttccagta acttctgctg agaaacgctg gctgagtaca cattggaaca
    23221 tatcaccatt acgaatcaag tcacgagctg tttccaccat ttcctcaaac ttctgaggag
    23281 cgatatgcgg tttgaagtct aacggagata gatccaagtc ttcaaactca tttggagcag
    23341 gaatgcgtaa ttcctcaagc acttggttca aggctttttc caattcttct tgactacgct
    23401 cactatagag agcatcctcg atgacatgta tcttctcctt cttgtggtca aagaccatat
    23461 agctctcata gacaaagaaa tgcatgtctg gcgtcccaat tgtatcctca gggatttgac
    23521 caatttcttc ataaagcgaa atcatatcgt aacccacaaa accaatggct ccaccaccaa
    23581 aagggagctc tgagtggtgc tgactcttat gaatcacttc ataaaggaaa tccaagggat
    23641 cccgatcaat cacttgacca ttttgataga gaactccatt ttcaaactta atctcaaaaa
    23701 ctggattata ggctaggata gaaaaacgag ccgtttcctt gtctctcgga atactctcta
    23761 aaataacctt atgttgcccc tttaagcgca tataagccaa gattggtgat aagacatctc
    23821 catgaatgat tcgttccatt gtaatttccc tttcagttct aattctagtt cgtggcgact
    23881 gtatgaaaaa tccccacgca aaataacttg cgtgaggacg aaattcgcgg tgccacctca
    23941 attataggat ttctcctatc tctcattcct gtctcagata cctcctgtaa caggctgtgc
    24001 gataaagggc actcccttga gaatgatgtt ttcttctctc gtttcagatg aacccaactt
    24061 tacagctttc tctgcttgtt ttcagcaacc acaagctctc tgtgagagaa aagactgtaa
    24121 tttttccatc tattattttt tagcttctag taatctgcaa tcgcagctag gtccttgcct
    24181 ccacgaccag agacattgat gaagagatgt tcatctcggt acacctttat actcttcgaa
    24241 aatctcttca aaccgcgtca acgtcgcctt atcgtaggta acgacggata gaaaaaagcc
    24301 cacacacaga atatacttcc gtgtgagggc gttggtaacg cggtgccacc tcaattataa
    24361 agggactatc cctttacatc tctgccttgt ttaacaacaa gctgcactgt aaggtgtgcg
    24421 caccgaattt tcattgtttc aaattcattt tcaaaatcag cccactttca ctacttccaa
    24481 ccacctattc acaatcacca caggctccct gaagatcaaa aatagttact tttctgattt
    24541 gttgaactta ttttaatact ttgttttttc tttgtcaaga cttttttacg atttttttga
    24601 tatcattcga atgtgaccat atcttcctta gatcgaacat gaacatgtcc cacttgttag
    24661 aaattggatc caactcaata gaaactgaat ggaggctaaa cagaacttat tttagaacac
    24721 tccatctttt ccactaggat tttcaagaat taaacaatac tagaaactct gtctcctaac
    24781 aaatttagga gaaacttcaa cagatgtgac actttcccct ttaataattg ctaaaacacc
    24841 ttctatcatt tctttagcca atttaacata attgggagca attgtagaca aagctggagt
    24901 ataatactga gaaataggaa tattatcaaa tccaatgata gaaatatcat ctggaataag
    24961 aattcctttc tcatagcacg cacgaatcaa gccctgaacc ttttcatctc ctgaaacaaa
    25021 aataatgtcc ggataatttt gggtagtcaa gtgctgcatt gcataagaat aaactgaatc
    25081 aattgtagat aagccataaa tgacttttaa atccataaag taatttttat cattcagaaa
    25141 agaacgcaca cctctttcac gatccttatt aacatgagat tctcctccca taagcaacca
    25201 catattttta aatttttctt cagttacagc tttcatcata tcataagtag cttgaaaatt
    25261 attattagat acatagacta ctccagacgt ttgagattca ccgaaaacaa gaaaaggcat
    25321 atggttcttc tttaaatact gaattctgat atcatctaca ctttcataaa aaacaataac
    25381 accatctact aggctacctg tgcttgatat aattgaatta ctaattgtat cctcctctcc
    25441 aaagtactca actatagcat taacaccaaa ttctttacac gtccgtaaca ctttatctaa
    25501 cagcgtatga aaccaaatta aaggaaaaga gtcgattttt tttacagaaa tcaatatatt
    25561 tatagcttct tttttagtta aattttttgc atacgcattt ggaatatacg acaattcctc
    25621 tataactttt tgaatcgctt gataagtttc ttctttaaca tttactccac cattaataac
    25681 tcgtgaaact gtttttggag aaaaacctga taaacgtgca atatcataaa tagttacctt
    25741 tttcccattt atatttttca tttcagtcct ccattacgaa cattctaata ttac
//
LOCUS       DAVKEV010000031        25721 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVKEV010000031 DAVKEV010000000
VERSION     DAVKEV010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25721
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.031"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(83..568)
                     /locus_tag="VWZ68_001398"
                     /pseudo
     CDS             complement(83..568)
                     /locus_tag="VWZ68_001398"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(601..939)
                     /locus_tag="VWZ68_001399"
     CDS             complement(601..939)
                     /locus_tag="VWZ68_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9372416.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADFISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEYYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKKLIK"
     gene            complement(952..1725)
                     /locus_tag="VWZ68_001400"
     CDS             complement(952..1725)
                     /locus_tag="VWZ68_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9372417.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAS
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            complement(2171..2926)
                     /locus_tag="VWZ68_001401"
                     /pseudo
     CDS             complement(2171..2926)
                     /locus_tag="VWZ68_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(3064..4686)
                     /gene="groL"
                     /locus_tag="VWZ68_001402"
     CDS             complement(3064..4686)
                     /gene="groL"
                     /locus_tag="VWZ68_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEU9372418.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(4702..4986)
                     /gene="groES"
                     /locus_tag="VWZ68_001403"
     CDS             complement(4702..4986)
                     /gene="groES"
                     /locus_tag="VWZ68_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEU9372419.1"
                     /translation="MLKPLGDRVVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(5256..5651)
                     /locus_tag="VWZ68_001404"
     CDS             complement(5256..5651)
                     /locus_tag="VWZ68_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU9372420.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(5729..6490)
                     /locus_tag="VWZ68_001405"
     CDS             complement(5729..6490)
                     /locus_tag="VWZ68_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU9372421.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(6523..7149)
                     /locus_tag="VWZ68_001406"
     CDS             complement(6523..7149)
                     /locus_tag="VWZ68_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEU9372422.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLDVERKGKVARVFLKDNGE
                     TVAWNIFEVSSLFEIAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(7165..7482)
                     /locus_tag="VWZ68_001407"
     CDS             complement(7165..7482)
                     /locus_tag="VWZ68_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEU9372423.1"
                     /translation="MIQPASLEELASLVEKDGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRVDRDQYIDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            complement(7479..7778)
                     /locus_tag="VWZ68_001408"
     CDS             complement(7479..7778)
                     /locus_tag="VWZ68_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEU9372424.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDHKLMKTQEELTA
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(8028..8216)
                     /locus_tag="VWZ68_001409"
     CDS             complement(8028..8216)
                     /locus_tag="VWZ68_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HEU9372425.1"
                     /translation="MKASTWVYDKGEWYYVSSSGAMLANDWVKDNGKWYYLASSGKML
                     RNTYTPDGYYVGNSGAWQ"
     gene            complement(8467..9141)
                     /locus_tag="VWZ68_001410"
     CDS             complement(8467..9141)
                     /locus_tag="VWZ68_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372426.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     ELVYVK"
     gene            complement(9147..9593)
                     /locus_tag="VWZ68_001411"
     CDS             complement(9147..9593)
                     /locus_tag="VWZ68_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9372427.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(9707..10210)
                     /locus_tag="VWZ68_001412"
     CDS             complement(9707..10210)
                     /locus_tag="VWZ68_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU9372428.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(10207..10569)
                     /locus_tag="VWZ68_001413"
     CDS             complement(10207..10569)
                     /locus_tag="VWZ68_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HEU9372429.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFLQAPYYVPERIAITGKICGVHIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(10635..12494)
                     /locus_tag="VWZ68_001414"
                     /pseudo
     CDS             complement(10635..12494)
                     /locus_tag="VWZ68_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(12533..12982)
                     /locus_tag="VWZ68_001415"
     CDS             complement(12533..12982)
                     /locus_tag="VWZ68_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9372430.1"
                     /translation="MGKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIDQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            complement(13106..13822)
                     /locus_tag="VWZ68_001416"
     CDS             complement(13106..13822)
                     /locus_tag="VWZ68_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9372431.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(14703..16118)
                     /gene="ply"
                     /locus_tag="VWZ68_001417"
     CDS             complement(14703..16118)
                     /gene="ply"
                     /locus_tag="VWZ68_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU9372432.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(16129..16461)
                     /locus_tag="VWZ68_001418"
     CDS             complement(16129..16461)
                     /locus_tag="VWZ68_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372433.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(16532..17140)
                     /locus_tag="VWZ68_001419"
     CDS             complement(16532..17140)
                     /locus_tag="VWZ68_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372434.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(17153..17611)
                     /locus_tag="VWZ68_001420"
     CDS             complement(17153..17611)
                     /locus_tag="VWZ68_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEU9372435.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            17736..18135
                     /locus_tag="VWZ68_001421"
                     /pseudo
     CDS             17736..18135
                     /locus_tag="VWZ68_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(18900..19160)
                     /locus_tag="VWZ68_001422"
     CDS             complement(18900..19160)
                     /locus_tag="VWZ68_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372436.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFFDG"
     gene            complement(19219..19770)
                     /locus_tag="VWZ68_001423"
     CDS             complement(19219..19770)
                     /locus_tag="VWZ68_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372437.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHVKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(19760..19957)
                     /locus_tag="VWZ68_001424"
     CDS             complement(19760..19957)
                     /locus_tag="VWZ68_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372438.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(19961..20755)
                     /locus_tag="VWZ68_001425"
     CDS             complement(19961..20755)
                     /locus_tag="VWZ68_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372439.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(21163..21588)
                     /locus_tag="VWZ68_001426"
     CDS             complement(21163..21588)
                     /locus_tag="VWZ68_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372440.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDNNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(21717..22100)
                     /locus_tag="VWZ68_001427"
     CDS             complement(21717..22100)
                     /locus_tag="VWZ68_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372441.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQLASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKKEMVLG"
     gene            complement(22122..22328)
                     /locus_tag="VWZ68_001428"
     CDS             complement(22122..22328)
                     /locus_tag="VWZ68_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372442.1"
                     /translation="MDLSNKASNLRKKLGADGEAPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(22315..22488)
                     /locus_tag="VWZ68_001429"
     CDS             complement(22315..22488)
                     /locus_tag="VWZ68_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9372443.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLYLSLNQSMIAK
                     MEKGERNITNGFK"
     gene            complement(22847..23803)
                     /gene="lytA"
                     /locus_tag="VWZ68_001430"
     CDS             complement(22847..23803)
                     /gene="lytA"
                     /locus_tag="VWZ68_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU9372444.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADRPEFTVEPDGLITVK"
     gene            complement(24179..25549)
                     /locus_tag="VWZ68_001431"
     CDS             complement(24179..25549)
                     /locus_tag="VWZ68_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU9372445.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSTFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
BASE COUNT         7821 a         5591 c         4346 g         7963 t
ORIGIN      
        1 aaacattttt ttgtatttcc acatagcatc aatcatttag tacaatattt taaaaacaat
       61 atcttaacag agaaaatgat atttaatcta tcagctcatt taatcgtttt tgaaaatata
      121 aagcaatact tttagattca ataaactcaa aatattttat gacattgtcc atttgtttaa
      181 ttccagattc tttagattct gtcaggtata ttttatatcc ttctacaaat ttgaatgtag
      241 atttttcaaa aacttttgtg tcatctttta ataatttttg taatttcatt tcaaagtagt
      301 ctgcatatat tagatgtgaa ttttcaaggc aacagaacca aaaatttaaa caagctgaca
      361 caactaaatt tctattcttg ccgatttttt cgtaataatg tgtacgctct agtatttctt
      421 ttccgaccat gtaaatataa tctatttcaa aaagatgata taaattacca atcagcgtta
      481 tctcatagga ctcccatcgt tccttctgga ataaatagtc atatactaaa tttagatcat
      541 ctctactaac tacatgatta caatctagct gatttcataa tccctgaacc ataattgtat
      601 ttattttatg agttttttcc cactcttctc aaaaagtttt tgttgcttat tttttattac
      661 ctccaatcct ttaatattca aactataaaa atttggagat aaattaacca aaaaatcatc
      721 acgctccgat cttttataat attctaagtg attacaaaaa ttctctatcg aaacattgat
      781 atttgataat aattcaaaaa atgttgaaag agaaatttca ttttctcccc tttcaaatct
      841 agaaagttga gattttgata taaaatcagc tgcagcatac tctaaagaat atccgtttaa
      901 ttttctaaaa tatcgaaaag cttctccgta atttttcaca ctttcattcc cttaactttc
      961 ttttcgagcg ataaacatac catattcttt aggaatgatc aacataccat tattaaactc
     1021 actttccaat cttttacgta ttatttcctc ttctagtgaa cctatttctg aaattccttt
     1081 aaacgattgg atgtatttaa ctaggtcatc tatactagtt acctgtaact catcatcata
     1141 gagtaatgta tcgacagagt taaaatacct actcaggtac cttttaccat tttgtaaagt
     1201 aaacgttcta ttttctaaat cttgattaac ctcatcttta aataaacttg ccaaataatt
     1261 tacaactcca ttttcaccaa atgtagcaca gtaaaaaatg cctccggttt ttaagaccct
     1321 attcacctca gagagagctt taggaatatc attcacatga tgtagaagca tattagcaat
     1381 aacaatatca aaagtttcat tctcaaaaga aatcttttga atatccatta tctcataatt
     1441 gacattgttt ctatttccaa tcactgactt cgttgatttt accatatctt tagaaaaatc
     1501 tgtaacaatc aactgcttca ttttatctat agaatcacta ttacttttcc acaattctcc
     1561 tgtaccacat cccaattcta gaacctttac ttcatcagtg atttggtagt tagaaaatat
     1621 ccaattatta aatcccaatt tattttttga atacttctta tgcaattcta ctcgaatatc
     1681 aagattatca tgacttttat attgttcaat tactttatca atcattttaa atgacctcca
     1741 ctctataatt tggcattata tcacaagaat aaagatagtg ttaaataagt tatataaatg
     1801 caaaaaagga atattccgtt atagcagagt tgtaacacat ttctataaag aaatttattc
     1861 ctacgactca gtttggcatg cttaacttcc taactcaaaa acaaagcatc gattaattta
     1921 tccgttcttc ttttgaaaca gatttgaact gataattgct cgttttaatt taaaaagctc
     1981 ttttgagcaa aacttcattt ttttaagagt ccaacaattt ctgtctatcg cttttctact
     2041 agcaaaaaac ctaccttgag gcaagttttc atttatatat ctaatttcgt aacagtatag
     2101 taaaatgaaa taaggacagt caaatcgatt tctaacaatg ttttagaagt aaaggtgtac
     2161 tattctagtt tcaatctact ataaatttga tatgagaata gtctttctca acatccttat
     2221 ccaacaagca tgctgtggcg tccttcttaa cttaaaccag gtcaatattc tgggcttggg
     2281 ctgcatagac gcagccacaa taacattgac gatagatatc atactcctca cacatctcta
     2341 ctgaacgttt gtagccttga tttttcttga aatcgttggg aagatagtgg ggcgtgtaaa
     2401 ttttttgcac atcgattccg atgctattga tagtttgaga attcttatga ggactgatgg
     2461 tcaaggctga accaaagtag tcaaagccca agtccatagc cacttgcgct gttttatcca
     2521 gtcggtagtc aaaacaaacc ttgcaacggt cgccaccttc gggctcctcc tctagccccc
     2581 taactagttt tcggtattaa ttgggttcgt agggagcttc taggtactga accgtatttc
     2641 ctgtccgctc attaaaatca ctaacaaatt tcttggtgac atagacccgc ttatggtatt
     2701 ctgccttggg atggatatta gaattggcaa aatagatggt cacatctgca tacttggtca
     2761 aatattctag tgtataggta ctacaagggg cacagcaaac atgcacgaga atggttggcc
     2821 gctactcatt tttttcccat gcttgtacca ttttctgcat gacacggtca taattaatct
     2881 tctgattggg ggtcatcttg cacagaattt cttctacatc gatcatgttc ttctcctttt
     2941 tctagtctta ttttatcata taagttagga gagctcaaat caatttagaa gtgaatatta
     3001 taaaaagaag ggttagtcat tccctccttt tgtgtttttt ataagttgtt ttctatagaa
     3061 agcttacatc atcccgccca tcatacttgg atccattgct ggagctgggg ctactggttc
     3121 tggtttattg gctacgactg cttctgttgt caaaatcaag ctggctacag atgctgcatt
     3181 ttgtagggct gaacgactca ctttaactgg atcaatgata ccttgatcaa tcatgttaac
     3241 ccactcgcca gttgctgcgt tgaatcctat accaagctca gcatttttca aacgatcgat
     3301 aacaatagat ccttcaaatc ctgcattgtg agcaatttga cgaacaggtt cttccaaagc
     3361 acggagaaca atattacgtc ctgttgcttc atctcctgtc aattccaagg tagcaacagc
     3421 tggaatcaca ttggcaagag ctgttccacc acctgcaaca ataccttctt caacagctgc
     3481 acgagtagcg ttgagggcat cttcaatgcg gagtttcatt tctttcaact cagtttcagt
     3541 tgcggctccg accttaataa ccgctacacc acctgacaat ttggccaagc gttcttgcaa
     3601 tttttcacgg tcaaattcag aagttgtagt ttcgatttga gacttgataa ccgcaacacg
     3661 gtgagaaatc gcttcaggat ttcctgcacc ttctacaata accgtgctat ctttgtccac
     3721 ggtcactctc gctgcttgac caagagcttc aattgtcgca tctttcaact caagaccaag
     3781 gtcttctgtg ataactgttc cgcctgttaa gatggcgata tcttcaagca tggctttgcg
     3841 acggtcacca aaaccaggtg ccttgactgc tactacgttg aaggttccac gaatcttgtt
     3901 caaaacaaga gttggaagag cctcgccatc cacatcatcc gcaataatca agagtggacg
     3961 attgctttgg agaatgcttt ccaaaagtgg caagatttct tggatattgg aaattttctt
     4021 gtctgtaatc aaaatgtacg gattttcaag gtcagccacc attttttcgc tatctgtcac
     4081 catgtactgt gaaaggtaac cacggtcaaa ctgcattcct tctacgactt caagctctgt
     4141 ttccatacca cgtgactctt cgatggtgat gacaccgtct ttgccaactt tttccattgc
     4201 ttcagagatg tactcaccaa ctttttcaga acgagaagat acggctgcaa cttgagcgat
     4261 agcttcttta ttggcaacag ggatggcgtt gtttttcaaa gcttcaactg ctgcggcaac
     4321 tgctgtttca atcccacgac gaataccgat tggatttgca cctgctgtga cgtttttgat
     4381 tccttcacgg acgattgctt gggtcaaaac agttgcagtt gtagttccat cacctgcgat
     4441 atcattggtt tttgaagcta cttctgatac caatttggca cccatatttt caaaatggtc
     4501 ttctaattca atttctttgg caatagtcac accgtcattg gtaatcaatg gtgagccaaa
     4561 tgatttttca agaacgacat tgcgaccttt tggtcccaaa gttactttaa cagtatctgc
     4621 aaggatatcg acaccacgga ccatggctga acgggcatct gatgaaaatt taatttcttt
     4681 tgacatactt actttctcct tctattcttc aatgattgcc aagatgttag cttcgcctac
     4741 gatgatgtac ttttcatcgc catctttgac atcaagacct gcgtgggctt caactaagac
     4801 acggtctcca gttttaacac ttggagcaac caagtcaccg ttcaaggtac gaacaccttg
     4861 tccagtagcc acaacttggg ctgttttggt tttttcttgg gctgaacctg cgagaacaaa
     4921 gcctccaaca gtttgttctt tttcttctac ttttaagacc acacggtccc ctaatggttt
     4981 caacatctga tttcctccat aatgagatag atattattag cactctttat acctgagtgc
     5041 taattcatag ttctattgta tcacttagtc agaaataatc aagaaaaaag tctgactttc
     5101 tcaagataaa aagcctgaga ccaactcaga ctttttaatg tttatactca atgaaaatca
     5161 aagatcaaac taggaagcta gccgcaggct gctcaaagca ttgctttgat gttgtggata
     5221 aagctaacgt ggtttgaaga gattttcgaa gagtattaaa atggcaattc ttcctcttcc
     5281 aagactaaat ctgccaaatc ttggcctgca ttattttcac gcatggcacg ttgagcacga
     5341 ctttccaaga gttggaatcc tgttacaagt acttcggtca cgtagttcat ttggccattt
     5401 ttctcaaagc gacgggtacg caattctcca tcaacggaaa tgagactacc tttggttgcg
     5461 tagcttgcca aagtttctgc tagtctgccc cataggacca tattgacaaa atcagcttca
     5521 cgttcaccgt tttggtcttt gtaacgacgg ttgacagcga tagttgctcg cgctaccgac
     5581 ttgtcattgt tggttttgtg caattctggt gtagacgtta aacgcccaat catgataact
     5641 ttattataca tattttcttc ctcctactta tctattcgta ggaaatcaaa aaaagttaca
     5701 gaaatttgta acttttcgag gaaatttctt attttttatg aatcatgaaa cctgtcgcct
     5761 gttgattggc cataatggtc atatctgtaa tctgaacacg gcgaggctga ctggtcacat
     5821 agactactgt gtctgcaata tcctgagctt gcaaggcttc tattccttgg taaacggacg
     5881 cagctcgctc tttatcacca tgaaaacgaa cagttgagaa atctgtttcg acaatcccag
     5941 gctgaatggt tgtcaccttg atatccgttg cgatggtatc aattcgcagt ccatccgaaa
     6001 aggtcttaac cgcagccttg gtagctgagt aaacagcggc accagcatag gcgtagattc
     6061 ctgcggttga ccccatattg ataatatgac cttgattgac ttttatcatt gctggcaaga
     6121 aacagcgagt aaccgccatc agacctttaa cattggtatc caacatggtc aacatatcca
     6181 actcctcata gtcttgatag ggagccaagt caagagccag tccggcgttg ttgaccaaga
     6241 tatcaatcct ccctatcgtt tctagaatat cagagcaaac agtcttcacc atgaccatat
     6301 ccgtcacatc tagtggaaaa gtccagacgg tttgatttgg aaagcttact gcaaactccg
     6361 acttgaggat ttctaatctg tctatccgtc gtcctgttag aacgacatcc tcaccctgct
     6421 ccagataagc acgcgcaatc gcttcaccga ttcctgaggt tgctcctgta atcactacat
     6481 tttttgccat cttatttcct tctatcagat gctgacaagt tcctaggcag tccagtgttt
     6541 cgctgggtcg aacggtgttc cgacaacttg gtcttctgat aattcaagca ccccacgttt
     6601 ttgtggagca tttggcagat gcaattcacg aggactgcac atcataccaa aactcttttc
     6661 accacgaagt tcacctggga aaatgagatt cccttttggc atcatagctc caggaagcgc
     6721 gacaatggtt ttcaacccca cacgcgcatt gggagctcct gcaacgattt gtacagtctt
     6781 atcacttgcg actgcaactt ggcagatgtt gaggtggtca ctatctggat gggctaccat
     6841 ctcaacaatt tcaccgacaa caaacttagg ttccttatca ttaacaattt cttctgtaaa
     6901 accttccgcc tgcaactctt ggttcaaacg agcgacttgc tcatctgtca aaaagacttg
     6961 accgcgctct gcaatttcaa ataaacttga aacttcgaaa atattccaag ccactgtttc
     7021 cccattatct ttgagaaaaa cacgggctac cttgcctttg cgctccacat ccagtttggc
     7081 atctccgcta tttttcacga tgaccataag gacatcaccg acatgttctt tattatatgt
     7141 aaaaatcatt gtttcctttt tctcctattt cagtcctgct aaaaagtcat tgatttgttg
     7201 cttgctttta cggtcgcgat tgacaaaacg accgatttcc ttgtcctttt ctagaacaac
     7261 aaggctaggg attccatata catcccagag tttggccaaa tctatatact ggtctctatc
     7321 cactcgaata aaggtaaact ctggattagt ctcctcaatt tctggtaagg caggatagat
     7381 ataacggcaa tcgccacacc agtccgccac aaaaaggaag accttcttac cgtctttttc
     7441 tactaaagat gccaattctt ctaaacttgc tggttgtatc ataagacttc ctcctcatag
     7501 actaggtctt cattttcata gacaaaagta taatgacggc catcctcaaa aatgacgcca
     7561 ccaagcaagc tctctagact gctttcatag acttgaacat agagggtcgc aatttccccc
     7621 atgtctgaaa aatggtctcg tacaatcgct gtcaactctt cctgagtctt catgagctta
     7681 tggtcatctg caactttttt cgtagcaagg gcaaggctcc caataccaag cagagccaga
     7741 cctgccatcc acattttttt agctttcata ccattcattt taacacaaaa aaggctttag
     7801 gacaaatgag gaaacagcaa aaaagcaagt aaaaagcctc ttcctttaag gaaaaggact
     7861 tcttatactc aatgaaaatc aaagaccaaa ctaggaagct agccgcaggc tgctcaaagc
     7921 actgctttga ggttgtagat agaactgacg aagtcagctc aaaacactgt tttgaggttg
     7981 tggatgaagc tgacgtggtt tgaagagatt ttcgaagagt attattctta ttgccaggcg
     8041 cctgagttac caacgtagta accatcaggt gtgtaggtat tgcgaagcat cttacctgat
     8101 gaagctagat aataccactt gccattatct ttgacccaat cattcgctag catggctcca
     8161 gaagaactta cataatacca ttctcccttg tcataaaccc aagtgcttgc tttcatggct
     8221 cctgagcaat taaaggttca aaaaactgtc caatatcatt cattttttta aagcatttta
     8281 cactacatca tccacgctgt aggacataga tacatcaaac gtaagagcca aaatatcgaa
     8341 aaatatacaa cttttaaagg caacatttca ttttttaaag tctaacaacc atagaactga
     8401 aatcagagca aggcatcaac ttcctactct tagtacgtct attttgatgg ttgaagtgaa
     8461 gattttttat ttaacgtaga caagctccaa cttcccaaaa gccacatctc cacggataat
     8521 caaggttttg ctggttgggg ctacaggagc gtcagcctta gctgcaccaa aggaggtttc
     8581 tactttcaaa tctacacgcc agtgttgtgg aacatagacg gttgcattcc cgaaggccac
     8641 ttcaatattt aaagttgcaa aatcacctag catctctgca ttatcatagt agattttagc
     8701 atccccaaaa gcgacttcca cttggtcatc tacgagatct tgatcttgct tatagaaggt
     8761 cccgctacca aaagcgactt ccttatccgt gacgactgtt tttttcccat tgtaccacca
     8821 ttttttttca ttccagaact tacttgaatg cgtcagataa ccaacaccaa gtaccaccaa
     8881 gatgctagcc caaataagag aatgattggt aactggtaac aagtcataag cgtaatttgc
     8941 aatgatgagc gccagtaaac ctgtaaaaac tgccgaagtg agatgacgtc taaggatgga
     9001 ctcaatggac ttataagcaa aaaaaacaat acctagtaaa ggccatattt taccatccaa
     9061 agaaggaatt ccaaaattcc cttgcagcaa gatccaagct gctaaaacca ataaaacaat
     9121 accaaatgct ttctttttca tgttttttac ctcatgtttc ttagattttc ttttaggagg
     9181 gattggtaat gccgtgagac atgaacctcc ttgtgcgtct gataaaagga aatggtgccc
     9241 gttcctgaaa aggacttgtc cactgagtaa atctgacgga tgtttgcgat cgttgacttg
     9301 gaaactcgat taaaatagcg aggcaagata gactccaact catagagctt gaggcgaacc
     9361 tcataagctt ccttctggtt atgagcgtag atcttgctcc cttctgtttc aaagaagaga
     9421 atttctgaca ggtctagata atattcacct gtccccttgt aaaaagtcaa cctcggagcc
     9481 tttgactctt gcaagagccg ttgcaagtct gcaatttcat ctgtcaaagt gggggtcttg
     9541 atgacaattt cagtctcctc taaattgccg tcaatctcaa ttcgtaactt catcacatct
     9601 cctttctgac tctactatat caaagctaag ttaggaatac aagggcaaaa aagcaagtgg
     9661 tcaatttgaa gcagtaagtg gttgtaggac tagcttaact tacatgtcag aataggaaga
     9721 aaaggaatcc ccacaccaga ccacaagcat agccaaccaa gacatccttg ggataatgaa
     9781 caccccctaa aaccctcacc aaccccagca aagctgaaaa gatcaagcat actaagccaa
     9841 taggtagact agcatgcaga caggccatgg agatgatagt tgcagaaaag acatggcgac
     9901 tgggcatcga ccgtcccgaa ctatccttat caagaagggg acagatatcc caagtttcat
     9961 aaggtctcgg gtgattgatt ttcttacgaa acagggacaa ggccacaaaa cctgatgcag
    10021 gaataagcac ataaacccca acttgctgac caagtcctag ttgcaggtaa gtggtgacta
    10081 gcaagatcag atagaccagg ggcatggcga ctgtcatcaa acgattgaaa ctgcgtaata
    10141 ggaataaaag aattggacga ctagttagtc tggagctgat atttcgatac cattcttgat
    10201 aatttttcat ttatgcttct catacttttc tagaacttgt tgagatgttt tccccttggc
    10261 aagccaatcc actagcttgt ccaaacgacg tatttcctgc atcagaggat catcaatttc
    10321 ctcaatatgg acaccgcaaa tcttccctgt aattgcaatt cgttcaggga cataatatgg
    10381 tgcttgtaga aaaaaatctc cgtaagtaac atccctatcc agacaagcaa gaacgtcact
    10441 cacttcatac cctgtcaacc aactggtcac ttggtgaact gactctgcct ttccaccctt
    10501 tcgctcaact tttgcaatca aggctaagta gacagcagca aatttcatat tgtataattt
    10561 ctgactcata cttctctctt tctatgtgta ctagtataaa taagaaaaag aaggccgtca
    10621 agcctttttt tgatttattc ttctgcttca tcttctgtaa attgactatt gtacaagtca
    10681 gcgtagaagc caccttgcgc catcagttcc tcatagttgc cttgctcgat gatatttcca
    10741 tctttcatga ccaagatcaa gtctgcattt cggatgattg acaagcggtg ggcaatgaca
    10801 aaggatgtgc gtccttccat caaacggtcc atggcttttt ggatcaattc ctctgtccgt
    10861 gtgtcaacag aagaagtcgc ctcatccaaa atcaaaagcg atgcatcctt aagaagggca
    10921 caagcaatag tcaatagttg tttttgtcct acagacaagg tcacggtgtc atccaagatg
    10981 gtatcatagc catctggcaa ggtcataata aagtggtgaa ttcccacagc cttactagct
    11041 tccatcattc gttcatcact aatccctatt tgattataga tgagattgtc tcgaatagtt
    11101 ccttcaaaga gccaggtatc ctgcaagacc attgaaaagg catcatgcac ttctgaacgc
    11161 gtcatagcct tggtatccac accatcaatg cgaatacttc tcttatcaat ctcatagaat
    11221 ttcatcaaaa gattgacaat ggttgtctta ccagccccag tcggcccaac aatggcaacc
    11281 ctttgaccag catgagctgt cacagagaag tcatagtctt gaacattgac accgtccacc
    11341 agaatttctc ctgctgacac gtcgtagaaa cgtggaatca gattgaccag agttgattta
    11401 ccagaacctg ttgacccaat aaaggccact gtttgaccag tttctgcttt aaagctaaca
    11461 tgttcaataa ctgcctccga atttgccgca tagcggaagg tcacatcctt aaactcgacc
    11521 tgacctttga agttttcatc agtcagctgc acttgaacag ggttttggat agaagaatgc
    11581 aaatctaaaa cttgattaat ccgcttagca gagaccatag ttcggggaag aacgatgaag
    11641 agtgctccca tgagaaggaa gcccatgaca acctacatgg cataagacat gaaaataatc
    11701 atgtcactaa agagaggcag acgcgctatc ggagcagcgt cgttaatcac ataggcccca
    11761 atccagtaaa tcgctacact caaaccactt gaaatcccca tcatgatagg attcaaaata
    11821 gccataagac ggttgacaaa caaattcaaa cgggtcaatt catcatttac tgctgcaaat
    11881 ttttcatttt gataatcctc tgcattgtag gcacgaacga cacgaatacc tgttaaactc
    11941 tcacgagtga tactgttcag tttatctgtc aacccctgaa tcaaggactg ttttggaaag
    12001 gctagcgtca tcaaaacggt cgtcatcagg acgttgacaa tcactaccac aagtacggcc
    12061 cagagccagt attctgaatg acctaaaatc ttcccaatag cccagatagc cataattgga
    12121 ccacgcgtta ccacttgcaa gcccatagta atcaacattt gaacttgagt aatgtcattg
    12181 gtagtacgcg tcaagaggct aggaattgaa aatttcttaa tctctgtctg cgagtaatcc
    12241 aaaactcggt taaaaatatc acttctcagc ctactagtat aagaagccgc cactcgggat
    12301 gcaaaaaatc caactgcaac tacggacaag aaggcaagaa aggacattcc catcatcatg
    12361 cttgccggct gccacaactc atctaaatta gtttcttgac tacctagcaa atccgtaatt
    12421 ttcgagatat aggtcggcac ttccaactct agatagaccg aaaagcaagt aaagagaatg
    12481 gctagtaaaa tcatccccca ttcttttcta ctaattcttt tggctaattt ctttattctc
    12541 tcctcctatt cccttgatat tttgcctgta gttgaccgag aaccttctca aaaatcagta
    12601 attcatcttc atcaatatct tccatcaact gcttgtctat gcgttcaaaa aaagccttaa
    12661 cctgttgcat ctgagaacgt gctttgtccg tcagacgaac aaacttagcc cgcttatcaa
    12721 caggactcgc ctccaattcc accaaaccat tttgcactat acgcttaacc agattactag
    12781 caacagactt ggtaatattg agttcctgat cgatatcttt aatcaagacc aagtcttggt
    12841 ttttctcgcg attatccaaa aaatgcacaa cctgaccttg cggcccaccc ataaattcaa
    12901 tgccgcaacg tttggcttcc ttttgcacca tcaggtgaat ttgatgacca aaacgcttaa
    12961 agactaacat cggtttaccc ataatctccc ccttctaaat aaaaatagtt ctctggagaa
    13021 taattaaatt tctatgagaa ctattttctt gattaaaaaa atcccaagtg attttctcac
    13081 ttaggatcat gttctatagg ttaaattaaa acccatctac gttcgtataa atcttttgga
    13141 cgtcttcgtc gtcttcaaga acgctgtaaa gtttttcaaa ggtttcaagg tcttcgcctg
    13201 acaattccac ttctgactga ggaatcattt ccaattcagt cacttggaat tcttcaatac
    13261 cagactcacg gagggcaacg atagccttgt gaaggtcagt tggcgctgtg taaactgtga
    13321 ttgtaccttc ttgtgcttct acgtcatcca catccacatc cgcttcgagc aattgctcaa
    13381 agactgcgtc cgcatcttca cctccaaata caataacacc tttgttgtca aagaggtaag
    13441 aaacagaacc tgaagcgccc atgtttccgc cgtttttacc aaaggctgca cggacattgg
    13501 ctgctgtacg gttaacgtta gaagtcaaag tatccacaat tagcatagag ccatttggcc
    13561 caaaaccttc gtaacgtcct tctgtaaagg tttcgtctgt gtttcctttg gctttatcaa
    13621 tcgctttatc gataatgtgt tttggcactt gggcttgttt agcacggtcg ataacgaatt
    13681 tcaaagctga gtttgattct ggatctggat cacctttttt agctgctaca tagatttcta
    13741 caccaaattt tgcatatact ttagagttgg ctccatcttt agccgttttc ttggctacga
    13801 tattggccca tttacgtccc attaggaatc tccttttttc acattttaat ctttcttatt
    13861 ataacacaag tttttttgat tttcactaga ggaaatggat tttattagca aatcaagcta
    13921 ggatagcact ttacctgcta agatggtctt gcctttctat ctttatcaac agacactcat
    13981 ccacattcaa aaaacaaact agaccattat ctgcaaatag aaagtttcag ccaagtttga
    14041 caaagtcagc tcaaattact gtttgaagtt tgtagatata agcgacaaaa acaatcatac
    14101 tgcacctttt gttgacagtc tactccagac atatcatagt tcaagtaaat actttgaaat
    14161 tcaacagttc ttataggcgc tattgtattc taagaaatca atagaagagt ttctaagcaa
    14221 acctctaata ctcaataaaa atcaaagagc aaactagaaa gctagccgca ggttgctcaa
    14281 aacactgttt tgaggttgcg gatagggctg acatggtttg aagagatttt ctaagagtat
    14341 aatttacgtg ttcctaagat ggagaagtta gactagtaca ctggcacttc taaaccattg
    14401 ctagcaattg atttgttcat atttaatttc attttttcca taaatgggta ttagatataa
    14461 acagcaaaat atttccgata cgtgtcattc ttgaatttcc aatcatctaa aacaagtaaa
    14521 ggataatcaa tcccctgtat atcaaggaat tggctaccct ttttactttt ttacacatcc
    14581 tgtttgatag actcatttta acatcacgag catactccaa tggaaatcgc taggcaagag
    14641 ataaactttc agatatccgc agagagatca tcgcctcttt ttgtcgcaag cattctcctc
    14701 tcctagtcat tttctacctt atcctctacc tgaggataga gagttgttcc ccaaatagaa
    14761 atcgtccgct tacgcactag tggcaaatcg gttttttcat aaaccgtacg ccaccattcc
    14821 caggcaagcc cggtacactc tctaattttg acagagagat tacgaacatt cccttttaaa
    14881 ggaatactag tggtaaagtg agccgtcaaa tcctgcccat ttctgtccca agccttagga
    14941 gtcaagactt ccttaccttg atgatcatag gataattcat cccaagtaat ataatattgg
    15001 gcaacatagg caccactatg atccagcagt aaatctccgt ttctgtaagc tgtaacctta
    15061 gtctcaacat agtctgtact gttttgaaag gtcgcaacta cattgtcacg taaaaaagaa
    15121 gttgtatagg aaatcggcaa gcctggatga tctgctgtaa agcgactgcc ttcttgaatc
    15181 aagtcctcta ccatatccac cttgcctgtt acaactcggg cacccgaact tgggtcgccc
    15241 cctaaaataa ccgccttcac ttctgtattg tccaaaatct gcttccactc tgtctgagga
    15301 gctaccttga ctccttttat caaagcttca aaagcagcct ctacttcatc actcttactc
    15361 gtggtttcca acttgagata gacttggcgc ccataagcaa cactcgaaat atagaccaaa
    15421 ggacgctctg cagaaattcc tctctgtttt aaatcctcta ccgttacagt atcttgaaac
    15481 acatctcctg gatttttaac agcgtctacg ctgactgtat aataaatctg cttaaaatta
    15541 acaatctgaa tctgcttttc acctgaatgg acagagttaa aatcaatatc aagagaattc
    15601 cctgtctttt caaagtcaga accaaacttg accttgagtt gttccatgct gtgagccgtt
    15661 attttttcat actgcattct agctgggaca ttattgacct gaccataatc ttgatgccac
    15721 ttagccaaca aatcgtttac cgctccgcga acacttgaat tgctggggtc ttccacttgg
    15781 agaaagctat cgctacttgc caaaccaggc aaatcaatac tataagtcat cggagcacga
    15841 tcaaccgcaa gaagagtggg attattctct aacaaggtct catccactac gagaagtgct
    15901 ccaggataga ggcgactgtc gttggtagct gttacagaaa tatcacttgt atttgtcgac
    15961 aagctccgct tctttctttc gataacaaca aactcatcgg gtagctgatt accctctttg
    16021 atgaaacgat tttcaatact ttctccctga tgggtcaaga gtttcttttt atcgtaattc
    16081 atagctagta taaagtcatt tactgcttta tttgccatct tctacctcct aataagttcc
    16141 tggattgagt tgcataaact cagacttgtt cagcgaaatc agccgtggtt ggactaagtg
    16201 atccaaaatt tcctcgtaca attcttctga gacattgcgt cgccgtctgg ctagataaga
    16261 agtcggaata accgtattat ccaacataaa taccttatct aagtcaatca aggttggtct
    16321 tgtaaaagga ttacgagcta gatccggctc ttctatcata aagttcttga ccaaacgtct
    16381 ggtcaagaga gctggtttga aggtctgatt tttaaccaac tctttgtttt tagtcatgct
    16441 gttgtcaata cagatataca tatgattctt cacagccaaa tcgctactaa tagtcggaaa
    16501 aggcaaataa agagctacaa catctcctct cttaatcaag caagagcacc cccttttctc
    16561 ctaatgtaac atagacagga ttgaccaagt cttctgattg actcagaatt tccaaagttt
    16621 gagtttggcg cgctgtcaat ttagtagcat cttgtctctt caatacaaaa tgcttgtcgc
    16681 caataacctt gacaatataa tccttctcca aagctgactg gtaaatccac atcagatgtt
    16741 gtctgtcctg agaactcaag agagaaggat tttcaagcct cccgatagtc tgataaaaat
    16801 caaaaacagg agctaactcc tgccaatctg attggctagt tgtcaaggct agaaaaaggg
    16861 ctttgcgagc tgatacttct tggttagcct tgagagttac tttcccctcc aagtttttta
    16921 gaaatcggga aactccagaa agcaaatttt tctctaactg cgagaaataa aaacctttcg
    16981 ttcccagaca taagtctttc atgtcgcttt ctctagcaaa taagagctca aacatttgat
    17041 agtaaaagaa aaatatctgg cactgggtcg cgctcatctt ttccttatcg gcttcttttt
    17101 ttaaccagag caagggcgac aggtaactgg attgagacat ttcctctacc tcctactctt
    17161 ttttaactgg agcatctgca ctagctgcca cttcttttga ctggatactt tcccactggt
    17221 taatctcctc tgagataaga ccttcgcatg tcttgacaaa tagggcaaaa gccttggtct
    17281 ttcctgcata tttctccgtt tggcattgat agaggaattt ttctttctcc aggagttgcg
    17341 cagttttttg gtaagaaatc caattttcct ttgcattata caaattgata atcccctcac
    17401 acagcaagcc gagactggat aaggcaaccg aaatcaaacg gtagcgatca cctggcatag
    17461 gaatagcaca aaagacagct atgaggaaac ctgccacgat ttctgttatt tttaatacct
    17521 tatagcgcct acgatgttga acgcttttct ttaaaaaatg agctatctgt acgtctaatc
    17581 gctctgtcag gtacatttct tctggcgtca tattcgtaac tcctttcatt tactttgata
    17641 accatagtat aacatatttg aatatcaaag tatagtaaaa actggactat aacttattag
    17701 acttcctgcg aaacaaaata tggtatagta gttctatgaa tgatgaagca agtaaacaac
    17761 taactgatgc acgatttaag cgtcttgttg gtgttcagcg taccactttt gaagagatgt
    17821 tagctgtatt aaaaacagct tatcaaaaaa gtcggacaag ctggtaaaat cttggctgac
    17881 agtaattatc aagggctcat gaagatatat cctcaagcac aaactccacg taaatccagc
    17941 aaactcaagc cactaacagt tgaagataaa gtctataacc atgcgctatc taaggagaga
    18001 agcaaggttg agaacatctt tgccaaagta aaaacgttta aaatgttttc aacaacctgt
    18061 cgaaatcatc gtaaacgctt cggattacga atgaatttga gtgctggtat tatcaatcat
    18121 gaactaggat tctagttttg caggaagtct attatatata tgcacagaca tatgaaatct
    18181 ttttgataca gccttctttt tacatagaga gacagcagtt atgatatatt tatccattca
    18241 caacatcttc tgtaccaata ctacaataat tggtacattt tgattacaca atcgtttcaa
    18301 aaaatatgat ggaagactga gtattttata gtaattccct tcctatcaac tagatcaacc
    18361 agttgagtgt tgaatgttga aacaccctag cctcagcaaa ggactatgat cagcatttcc
    18421 tagccaatag gacgctccaa atcacctatt ctaagtccat cactagcttg gtcagtaaga
    18481 tacagactgc aaggcaagac tgacgtggtt gatgagattt tggaagagta ttacaatcat
    18541 agattcacca gtagacttga ccgcagattt aactatagta gattgaaact agaatagtac
    18601 acttctgctt ctaaaacatt gttagaaatc gatttgactg tcctgatcaa tttgtcctgt
    18661 tctcgtttca ttttactata ctaaaaaacc acctgaaaca aatcaagtga ctagaggata
    18721 aaaacaaaga ctgggcaaaa agttttgaaa agcaaaaaac gcataatatc aggtcttgaa
    18781 aaaccttgat actatacgtt tgattgtggg aagattgact tcattttctc ctgaaattga
    18841 agttttttct agtttccagg tatagacgaa ttcaatatag ccatctcgct acaattattt
    18901 taaccatcga aaaaattttt cagaatttca aaaatttcat tttgatccaa tgaaatgtca
    18961 ttattttgaa gaatagttga cttcacaggc tctaattcta tcacaaagcg gtgcatgtct
    19021 gcttttaccg cactacttga tgttatagcc gataactttt catctcctag caaggaagct
    19081 gtcaaacggg taaggtcatt caaatgcttt ttaatggact tacttaaacc ttgagcacct
    19141 gtggcagagc gctccctcat atccagccaa gctttagcct taaaaataat taatactcaa
    19201 tgaaaatcaa agagcaaact aggaagctag ttgcaggctg ctcaaaacac tgttttgagg
    19261 ttgtagatgg aagctgacgt ggtttgaaga gattttcgaa gagtatagac cacaattact
    19321 caataccgaa tacccctgaa tggtttcttt tacatgcacc aatatattat aataatcttc
    19381 atccaataat aaggctgata aactagcatc ttggtcaaaa tataagggaa tttctcgacc
    19441 gtccttcttt aatggatatt ctggtaagat actaaatagt tcaatcatag aaggaaactc
    19501 agaattagtt gttgtaaatc gaaaaagctg cgctttctca tctttctgac ttccttgata
    19561 ctctcccaat tctaaaaaat gattcaaggt agtataaaat tccttatttt ttacttcatc
    19621 aatgatgacc atatcataat cttttgttgt gcgactttta aatccttgcg aatccaatac
    19681 gatagaggta gcagttcccc caatcagaac ataatagttc tgaaaatccg caaacatttc
    19741 ttgaaaaata actttcgtat tagctggcat catcttctcc cagatactgt aatatcatat
    19801 tttctagtgc ttcactctct tcctctatac gtgggtcatc atcatctttt aaggtcaaat
    19861 aaagagaaat cggatctaca aattgtttat catgattatt tttaaaatca ttccaaaact
    19921 cagatacaaa aggacgatat ttccatatct ctagcatctt tcattttaaa acatgctgag
    19981 aaagtggcaa ggataactga ttgaattttc tctgccatat gacatagcta atattttcat
    20041 ccgtttcagc taaaaaagtt gaatgcgaca aagcataagc accaccatat agaaggttag
    20101 aaacagattt tatctgcttt atatcgccat ctggcaataa aatccgtttt ttgatgggat
    20161 taaataaaca tgacacggat tttaagaata attctttctt tgacaccgta tatgtgtaaa
    20221 gcttattttg cttgtttaac caatataaag ctttaaaagt cctcaaacac ctataaattg
    20281 ttgagtttgg aagtccagtg acttgtgaaa gcaaatcaac atctactact ttttgacctt
    20341 ttgtcaataa aaaggcaatc cacgttaatt gttcgctagg tgttaattcc ttagggactt
    20401 cagtatcatt cgcattgagt actagtccca atggagggaa gaagaggttt cccttaaagt
    20461 ctacaaacgg aactctagct tgaagtaatt gctttttttc actgtctgat aacttcgaaa
    20521 acaccaaaac aacatccata ttggcttttt cacccatagt gcgagcctga gtaacaaatg
    20581 aactcaaact cccccttctc ttttctttaa tcaataaaaa tgattcctta tgaaaagtca
    20641 tttgagtata ctcaaacctt tttacaaaac tgattggtaa agtcaaagtc agttcctcaa
    20701 tactgacatc aacataaaag gattgaaaaa ttgacattat ctttttgaca ttcatgtttt
    20761 ttccttattc tatcattttt attatatttt atcattcggt ataataaaat ataagttttt
    20821 tgataaaata accaaaaact actcgctatc ccctctcaca ttaccctaca tatcgtttga
    20881 catgcgactg atagttcagg aaaacttcaa ggagaacttt tctctcatcc actatgcagg
    20941 acttactatt tcacttctac tcctataggc tcaatttgac acttttcttt ttcgaattgc
    21001 tcatatgcct cctgaatagt gagttcgatt tatccaaatt tatttttgtc tattttgatg
    21061 aatacttcca cgaagatagt ctgaaaatga atttgcacca attttccttc tctttttaag
    21121 catattattc cagatatgat tgccctcttg ttcagtaata aattacgctt taaacgcttc
    21181 aatcagtata tctcctgttg tcatatgttc taaagaaaat tcttctacat atgatttaac
    21241 atctcttagg ttattacttc ctaatatccc attatgcttt ttcgctaagg aaatagaagc
    21301 cgcttctccc ttaccaataa tcttgttatt atcatgattt cttgttaaat ctctatataa
    21361 tgcgtattct tcagttccaa tgtctatgct cacaatctca gctgaaccct tagctaccaa
    21421 ctgatctatc ctagatttta aatggggaat tgtaggtata ttgatttcat catacacctc
    21481 ttgtggaata acaattttac ccgaatagag cttttctaaa agatgttcag tgccaaccca
    21541 taaaaatact gaaatacaat ctgcatcaat aaatacacga ctagtcaaac gacaactccc
    21601 ccctcttcat ctagcccata tacaatatca tatctgaaag catctagtaa cagttcctca
    21661 tacttccctt gcgaaattct gttattttct aaaagttgtt cagttgaatt aatatattat
    21721 cctaatacca tttccttttt actttctgac aaaggacgat ataaacttgt atcatagcct
    21781 aatcttgaag ctgtctctat aacactaata tccatatttt taatttcttc tgcatcaagg
    21841 tatccatcat tcctcaatct atataacata gctttatgac tgataccata aaactgaccc
    21901 aattttataa tatcttctac ttcaagatga gttctattgg cattttctct gatttcctca
    21961 accatcctat acagtgaaga tgggaaaatt aaaaaataag aagcaagctg atccgctttt
    22021 ctttcagttt catctccttc accaatcaag ataagactga ctgaactctt cttcacctca
    22081 tcataataaa gatgatacag ttcatgtgct aaagaaaatc tttaccttcc taatgacatg
    22141 tctgaattga ctgcaatgag actgaactga gttcctttat aacagactcc gctaatattc
    22201 tttccgagtc cataaaatac cagcgtcaaa ttttctatct tttgtaccaa tttaaaaata
    22261 tctatcggcg cttcaccatc agctcccaac ttttttctaa gatttgaagc tttattactt
    22321 aaatccattc gtgatattcc tttcaccttt ttccattttg gcaatcatgc tttgattcaa
    22381 agacaaatat aaagacaaat attcagcaat cttatcttga gtaagatttg aagatattct
    22441 aagttctttt attctttttc caacatcaca tacatttatc acatacattt atcatattca
    22501 tacacctctc ataaaaagaa tagcacactt ttgtcataat tttttaaata aaaaaattat
    22561 gacaaaacaa ggaagcaatt tattgatgct gcttaaaaat ctaaaattga tgagttccta
    22621 tcaaaaatcg tatcttcaac ctcaaaacag tacttaaagc tatccgactc ggtttacatt
    22681 gtcaaattta gattttattt gagcataact ttctagtttg ctttctgatt tttgtttaat
    22741 atagtagcaa acattgaagg aaatatctcc acaagaaaac gcatactatt aagctttttc
    22801 aagacctaat aatatgcgct gttctgattt gaaagacatt ccattattat tttactgtaa
    22861 tcaagccatc tggctctact gtgaattctg gcctgtctgc cagtgttccg tctggtttga
    22921 ggtagtacca gcctgttccg tccgctgact ggataaaggc atttgatacc atggcgcctt
    22981 ctttagcgtc taagtagtac caagtgtcct tgtacttgac ccagcctgtc ttcatggcac
    23041 cttcttcgtt gaaatagtac cacttatcag cgattttctt ccagcctgta gccatttcgc
    23101 ctgagttgtc gaaccagtac cagttgccgt ctgtgtgctt cctccagcgg tctgcaagca
    23161 tatagcctga actgtcaaag tagtaccaag tgccattgat tttctcaaac ttgtcttttg
    23221 gataagagcc gtctgaatgt acgtaccagt agccagtgtc attcttctgc cagcctgttt
    23281 caatcgtcaa gccgttctca atatcatgct taaactgctc acggctaatg ccccatttag
    23341 caagatatgg ataagggtca acgtggtctg agtggttgtt tggttggtta ttcgtgcaat
    23401 actcgtgcgt tttaattcca gctaaactcc ctgtatcaag cgttttcggc aaacctgctt
    23461 catctgctag attgcgtaag agttcgatat aaaggcggta gtccgtcatg aactcttctt
    23521 tggttgaatg gctttcaatc agttcaaccg ctgcataggt ctcagcattc caaccgcccc
    23581 caacgtccca ggcaccatta tcaacaggtc ctacctgcat gatgcaaccg ttcccaacaa
    23641 tgtgcgagaa aaaacctaat tctgggtctt tccgccagtg ataatccgct tcattctgta
    23701 cggttgaatg cggattccca gttgagtgtg cgtgtacttg cctatatggt tgcacgccga
    23761 cttgaggcaa atctgttctt aatttactca cattaatttc catattctac tccttatcaa
    23821 ttaaaacaac tcatttttta caatccagaa ccagaaactc ctttatttct accttacaaa
    23881 gaagacaatc ttagtcacga ttaggcttgt agatagaact tcaaaacgca ctattttgac
    23941 actgtaaata ggactgacaa ggtctgcatt ctatctacaa taacacccca gactaaaaag
    24001 cttttcaaaa gtatattttt acagtctcta tatgtccttt tcataaatac tatactttat
    24061 tatatcatat aaaagaagtc aaaagtctgt taaactattt tcaacaccaa actaaagacg
    24121 agaacacaag ttttttcgat tttcactaga ggaaatggat tttattcagt aaatccaact
    24181 aggattgcac tttggttgcc aagattgcct tgccttcttt tatcaaggga tgacggaata
    24241 atgagaagta cagttgaact gtcatggcaa cccagataag aggttcacaa aggataacac
    24301 ccttatatcc tgcccaagga ataatcaaaa ccacaaaaac gatttttccg attagttcaa
    24361 taaagctaga aactagagga aggatctttt gccccaagcc ctgcaagcaa ttgcgataaa
    24421 tcaacaagag gctcaaaatg ggataaaagg ttgaactgat ttgcagatag agacttccat
    24481 tttctatcaa gtaaccatct gtcgaactag ccaagaagga aaccaaagct ggactggcaa
    24541 aaaagaggaa aatacaaaca aaaactgccc aggatatact taaacgactg ccgattcgaa
    24601 gaccttgaac aatacggtca ggtcgcttag ctcctagatt ctgagaagca aaggtcgtca
    24661 ttgatgcaga aatagcggtc ataggaagaa gggcaaaggt cataatgcgt cgagctgccg
    24721 tctgggcact aataatcact gcaccaaatg tattaacaga aaactgtaaa atcacactgc
    24781 cgatagatac aattgaactc atcaagccca tagccaaacc ttgctccaag agatccgcgt
    24841 acaagctttt gtcccatttg aaatgtttaa actgtggcaa gagttctggc acacttttac
    24901 gaatataata aaagcagaga accgctgata aaccttgcga aataatggta gcaagtcctg
    24961 cggattgaac tcccagatgc aattgcgtaa taaaatagag atccagaacc acattaacca
    25021 aggcagagaa aatcagaaat cccagggctg ctagactgtc accaatagac cgcaacaagc
    25081 ctgcaaaaag attataagca aagctgacac ctacacaggt cacaatcata gaaatatatt
    25141 gataagattg aggaagaatt tctgcaggag tatctaagta ttgcaagaga ggatacaagc
    25201 caagaaagcc cagcaacata actagaatgc tcaaaagagc acctaaaatc caggtggctg
    25261 ctactgcttc cttgatttta gtgaaattcc gagccccata ataacgagca atgacaatcc
    25321 ccatgccatt gccaacacca agtgtaaagc ctacaatcag gtcaaaaatc gctgtcgtcg
    25381 ctcctactgc agccaaggat tcttgaccaa gaaatcgtcc aacaatcaag acatcagcag
    25441 tgttatagag ctgttgaaaa atatttgata gcaagattgg aaaggtgaag cttaagagcg
    25501 agggaagaat cggaccatgt atcaggtcca ctgttcgttt tttattcata aagctattat
    25561 atcagctttc cagaggagcg acaagaaaca gcaaacttat atatagcgga atgaaataag
    25621 gacagtcaaa tcgattttta acaatgtttt agaagtagat gtgtactatt ctagtttcga
    25681 tctattatag ttggttgagt ttggaatagt acgctgtagc t
//
LOCUS       DAVKEV010000032        25021 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVKEV010000032 DAVKEV010000000
VERSION     DAVKEV010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25021
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.032"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            83..880
                     /locus_tag="VWZ68_001432"
     CDS             83..880
                     /locus_tag="VWZ68_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEU9372446.1"
                     /translation="MISSEFISKIEFACNKKESLYSQSKFKYAIRSIFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGSLIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1028..1150
                     /locus_tag="VWZ68_001433"
     CDS             1028..1150
                     /locus_tag="VWZ68_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEU9372447.1"
                     /translation="MTRDFKFETLQLHAGQVVTPATESRAVPIYQTTSFVFDDT"
     gene            1172..2287
                     /locus_tag="VWZ68_001434"
     CDS             1172..2287
                     /locus_tag="VWZ68_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEU9372448.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDIDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFATPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGSSCHNLSYIRDVGAATFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETLSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKGVGSIFTFHVKGDEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPNQIRLSIGLENVEDLIEDLRLALEKI"
     gene            2383..3657
                     /locus_tag="VWZ68_001435"
     CDS             2383..3657
                     /locus_tag="VWZ68_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEU9372449.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VWZ68_001436"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VWZ68_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEU9372450.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTKTEDASGEVVAETPVLSLLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="VWZ68_001437"
     CDS             4786..5088
                     /locus_tag="VWZ68_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU9372451.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="VWZ68_001438"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="VWZ68_001438"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU9372452.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /locus_tag="VWZ68_001439"
     CDS             5962..7302
                     /locus_tag="VWZ68_001439"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEU9372453.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="VWZ68_001440"
     CDS             7280..7492
                     /locus_tag="VWZ68_001440"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEU9372454.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="VWZ68_001441"
     CDS             7489..8364
                     /locus_tag="VWZ68_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEU9372455.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="VWZ68_001442"
     CDS             8357..9172
                     /locus_tag="VWZ68_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEU9372456.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDVKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="VWZ68_001443"
     CDS             9165..9596
                     /locus_tag="VWZ68_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU9372457.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="VWZ68_001444"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="VWZ68_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEU9372458.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGVPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLHLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVHFSKGKFSRGGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="VWZ68_001445"
     CDS             11272..12000
                     /locus_tag="VWZ68_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEU9372459.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="VWZ68_001446"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="VWZ68_001446"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEU9372460.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPESVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14196..14276)
                     /locus_tag="VWZ68_001447"
                     /pseudo
     CDS             complement(14196..14276)
                     /locus_tag="VWZ68_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14450..14925
                     /locus_tag="VWZ68_001448"
                     /pseudo
     CDS             14450..14925
                     /locus_tag="VWZ68_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            14963..15265
                     /locus_tag="VWZ68_001449"
     CDS             14963..15265
                     /locus_tag="VWZ68_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9372461.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSVPVFDNIRLPAKQNMV"
     gene            15273..16074
                     /locus_tag="VWZ68_001450"
                     /pseudo
     CDS             15273..16074
                     /locus_tag="VWZ68_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            16123..16587
                     /locus_tag="VWZ68_001451"
     CDS             16123..16587
                     /locus_tag="VWZ68_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEU9372462.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEETCSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSKDAVTLDELQSRTIALRSLKHDRGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            16744..17169
                     /gene="lacA"
                     /locus_tag="VWZ68_001452"
     CDS             16744..17169
                     /gene="lacA"
                     /locus_tag="VWZ68_001452"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEU9372463.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            17200..17715
                     /gene="lacB"
                     /locus_tag="VWZ68_001453"
     CDS             17200..17715
                     /gene="lacB"
                     /locus_tag="VWZ68_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEU9372464.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            17726..18655
                     /locus_tag="VWZ68_001454"
     CDS             17726..18655
                     /locus_tag="VWZ68_001454"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEU9372465.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            18657..19637
                     /gene="lacD"
                     /locus_tag="VWZ68_001455"
     CDS             18657..19637
                     /gene="lacD"
                     /locus_tag="VWZ68_001455"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEU9372466.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGETAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            19871..20707
                     /locus_tag="VWZ68_001456"
     CDS             19871..20707
                     /locus_tag="VWZ68_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU9372467.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYCQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            20743..21060
                     /locus_tag="VWZ68_001457"
     CDS             20743..21060
                     /locus_tag="VWZ68_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9372468.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            21062..22756
                     /locus_tag="VWZ68_001458"
     CDS             21062..22756
                     /locus_tag="VWZ68_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU9372469.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            22965..24371
                     /gene="lacG"
                     /locus_tag="VWZ68_001459"
     CDS             22965..24371
                     /gene="lacG"
                     /locus_tag="VWZ68_001459"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU9372470.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTDYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            24461..24673
                     /locus_tag="VWZ68_001460"
     CDS             24461..24673
                     /locus_tag="VWZ68_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEU9372471.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
BASE COUNT         7711 a         4423 c         5576 g         7311 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatgatttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 attcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggat ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat aatatggagg
     1021 tcaccttatg actcgtgatt ttaaatttga aactctacaa ctacatgctg gtcaagttgt
     1081 gactccagct actgagtctc gtgcagtgcc gatttatcaa acaacatctt ttgtttttga
     1141 tgacacgtag gaaggtgctg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatattga taatttggag gaagtagaag cagctatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaaca ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggacggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatattc gtgatgtggg tgcagcaacc tttattatag ctgttcgagt
     1801 tcaattgctt cgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa actctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttatcat gccttggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtgacgagg aagaagcacg caaggtcatt gataatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caaccactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaacc aaattcgtct
     2221 gtcaatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttgg ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaca gaagtctaga aagaggaatg taatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gaaagccagt atgctgaact tttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaggcagga actggccttg
     2521 gctgagcaaa aggctatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattac agagtcagat ccaaaacttt gatacagaaa aagaattggc caagaaagag
     2641 gttgaacaga caagccatga ggctctcttg gctaaggaca aggaagtaca gctcttagaa
     2701 aatcagttgg ctaccttgcg tttggagcat gaaaatcaac tacaaaagac cctttctgac
     2761 ctagaaaaag aacgggatca ggttaaaaac caactacttt tgcaggaaaa ggaaaatgaa
     2821 ttatctttgg cttctgttaa gcaaaactac gaagcccagc tcaaggcagc tagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcggac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgacc
     3541 acatctgaaa accaactccg tttagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat taacttaaaa aaggaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggtcgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaatcactc tgggctattc cacgaagact
     3901 gaggatgcta gtggggaagt ggtcgcagaa acccctgttt tgtctctctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta ctcagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgcccgatt cacttttcgt gtaaaatgca gtaaagggac gtacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgat aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctgat gggaacttag gcccaggatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaata ccaatcggtc
     4921 atggccaatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggaacctcaa gatgtcttta
     5521 tcgttgaggg tattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgca ttattcgtcg tatcaagcgt gatatggagg
     5641 agcgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat gaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaagtat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtctatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctgccccaa
     6361 ttttctaaga gaattggtgt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatccgac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgagacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattagctca tttgcaaaat
     6781 caggaaaaac ggatggtaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccgttgta
     7201 gattcggttg agagtttgaa gaaaaaagac caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttacca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttagagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgctttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagatcaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctctg
     7981 gaagaacttc agactattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gcaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ttgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattagaag aaattgccca gcagcttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtgatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgacaccg aattaaaact
     8521 caagggggag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttgggac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gtcagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcac cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgtta agattcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggca ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agattcttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaaa
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattaccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgagacttt tgcagacaag atttttagct gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgtac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgtctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gcacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ccatgaatga catggaaagt gtcgaagagt
    10381 atgaccctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctca
    10501 tgcaggttga gaatcgtttg cacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgccaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cattttagta
    10801 agggaaaatt cagtcgtggg ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagcatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattctt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatgtgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tcttaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgca atggtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcgtcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatatttgt tcacgcaggt
    11701 attgatttga ctttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacaggg gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccac gggaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggat
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatgggg aaacttatat tttccacttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagag cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 ggtattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aagtacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggtttcc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga tctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaatcgt ctttgacttc tttgataaac ttaagtcttc gacacgtggt
    13501 tatgcaagtt ttgactacga attgtcagaa tatcgcccat ctaagctagt gaaaatggat
    13561 atccttctca acggagacaa ggtggatgcc ctcagcttta tcgttcataa ggactttgct
    13621 tatgaacgtg ggaaactcat cgttgataag ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaggttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaatctcaa aaccatgttt tgagctgact
    14101 tcgtcagttt catctacaac ctcaaaacca tgttttgagc tgacttcgtc agtttcatct
    14161 acaacctcaa aaccatgttt tgagctgact tcgtcagttt catctacaac ctcaaaactg
    14221 tgttttgagt aacctgcggc tagcttccta gtttgctctt tgattttcat tgagtattag
    14281 aacagaaaaa tgcttggagt atttgtttgt gtgtttattt ttatataaca aactataaac
    14341 acaacaaaaa tataaaaaaa gagacaaaaa agaacagaaa gtaattaaca acgatttcat
    14401 atagtgttat acttatagca taaagttaat ggaaagaagg gaaaacctta tggtattaga
    14461 ttatttcttt gacaaaaacc ttgtgttttg cttagaagcg gataatcaag aataactctt
    14521 tgatcaggta gcaagcttgt tggaggaacg agaaattgta actccaactt atcgtgaagc
    14581 tttgatcacg cgtgaaaagt catttccaac tggtttagat atggaatttc taggaaagga
    14641 cttgcaaatg taatgattcc tcacacagat attgttcata atctagctga gaaagtggtg
    14701 gttgttcgat tagagaaacc ggtgactttc cataatatga ttgcgccagg taaggaagta
    14761 gaagtatcct tgctcttctt tatcatcaat aattcaagtt caagtcaaac gaacattctt
    14821 gctcagttga tggacttttt cacaggaaat ggacatcttg aagacctatc aaaaatttcc
    14881 gaaccagaaa aactttatgc ttatatagat gaagcaatcg cttaatcttg tctattaaaa
    14941 aataaaatcg gaggaagtct atatgattaa aattcttgct gcctgcggtg caggtgttaa
    15001 ctcaagtcac caaattaaaa gtgctctaga agaagaactt tcaaaccgtg gttacgatgt
    15061 tcactgtgat gcagttatgg tgaaagatgt aaacgaagac cttatgaaag gttacgatat
    15121 ctttacacca atcgctgcaa cagaccttgg ttttgaacca ggtatcccag ttatcgaagc
    15181 tgggccaatc ttattccgta tcccagcaat gagcgttcca gtatttgaca atattagact
    15241 tcctgcgaaa caaaatatgg tatagtagtt ctatgaatga tgaagcaagt aaacaactaa
    15301 ctgatgcacg atttaagcgt cttgttggtg ttcagcgtac cacttttgaa gagatgttag
    15361 ctgtattaaa aacagcttat caacttaaac acgcaaaagg tggacgaaaa cctaaattaa
    15421 gcctagaaga ccttcttatg gccactcttc aatagtgcga gaatatcgaa cttatgaaca
    15481 aattgcggct gattttggta ttcacgaaag caactttatc cgtcggagcc aatgggttga
    15541 agtaactctt gttcaaagtg gtgttacggt ttcaagaact cctctcagct ctgaggacac
    15601 ggtaatgatt gatgcgacgg aagtacaaat caatcgccct aaaaaagaat tagcgaatga
    15661 ttctggtaaa aagaaatgcc acgctatgaa ggctcaagcg attgtcacaa gtcaagggag
    15721 attgtttctt tggatatcac tgtgaactat tgtcatgata tgaagttgtt caaaatgagt
    15781 cgcagaaata tcggacaagc tggtaaaatc ttggctgaca gtggttatca agggctcatg
    15841 aagatatatc ctcaagtaca aactccacgt aaatccagca aactcaagcc gctaacagtt
    15901 gaagataaaa cctataacca tgcgctatct aaggagagaa gcaaggttga gaacatcttt
    15961 gccaaagtaa aaacgtttaa aatgatttca acaacctatc gaaatcatcg taaacgcttc
    16021 ggattacgaa tgaatttgat tgctggcatt atcaatcatg aactaggatt ctagttttgc
    16081 aggaagtcta ataaagaaac tagcaaggtc aggccttact ttattggtgg acatccagga
    16141 tttaattgtc ctctacttga tgatgaagtc tatgaagatt attatctaga gtttgagaaa
    16201 gaagagactt gctctgttcc acgtcctttc ccagaaacag gtatgttgga tttccaagat
    16261 agaagtccat ggctagaggg acaaaaagaa atagatctta gttatgatct tttcagcaaa
    16321 gatgcagtga ctttggatga attgcaatct cgaacaattg cccttcgttc tcttaaacat
    16381 gataggggat tgaaagtgca ttttgcagaa tttccaaacc tcatcatctg gtcaactttg
    16441 aacaagggac ctttcattac ctttgaacca tggtctggct tgtcaacatt ccttgaagaa
    16501 ggagatcatt tagaagataa gaagaatgtt tgtctcttag aagccaatca ggttgaagaa
    16561 ttagggtttg agatagaagt tttataaaaa agtaaaaaat aaataacaaa aacaaacaca
    16621 aactgttgac ttcttcaaac aatagtagta tattatgttt gtgaggacta attgactgtt
    16681 ttttaaagac agccaataca ctgctggaat ccagcataga aaaaataaaa aggagtatac
    16741 aatatgtcta ttgttatcgg tgcagatgct gcaggtttga gattgaaaga agttgtgaaa
    16801 gacttcttag aaaaagaaaa cttccacctt gtggatgtta cagctgaagg tcaagacttt
    16861 gttgatgtga ctctcgctgt tgctgcagaa gtaaacaaag aagaacaaaa ccttggtatc
    16921 gtgattgatg cttatggagc tggtccattt atggttgcaa ctaagatcaa aggaatggtt
    16981 gctgcagaag tttctgatga acgttcagct tatatgactc gtggccacaa caactcacgt
    17041 atgatcacta tgggtgcaca acttgttggt gatgaattgg ctaaaaacat cgctaaagga
    17101 tttgttaatg gtaaatacga cggtggtcgt caccaaatcc gggttgacat gttgaacaaa
    17161 atgggctaat tagattatag taagaaaggt aagttaaaaa tgagaattgc aattggatgt
    17221 gaccacatcg taacagatga aaaaatggcg gtttcagaat ttttgaaatc aaaaggatat
    17281 gaagtcattg actttggtac atatgaccat acacgtactc actacccaat ctttggtaaa
    17341 aaagtagggg aagctgtaac tagcggtcaa gctgatcttg gagtatgtat ctgtggtact
    17401 ggtgttggta tcaacaacgc tgtaaataaa gttccaggtg ttcgttctgc cttggttcgt
    17461 gatatgacaa cagcccttta tgctaaagaa caattgaacg ctaacgttat tggttttggt
    17521 ggtaaaatta ctggtgaatt gcttatgtgt gatatcatcg aagctttcat ccatgctgaa
    17581 tacaaaccaa ctgaagaaaa caaaaaattg attgcgaaaa ttgaacatgt tgaaagtcac
    17641 aatgctcaac aaacagacgc aaacttcttc actgaattcc ttgaaaaatg ggatcgcgga
    17701 gaataccacg actaagaggt aacctatgat tttaacagtt acaatgaacc catccattga
    17761 tatttcctat cccttggatg agttgaagat tgatactgtc aatcgtgtgg tggatgtaac
    17821 caaaacggct ggtggtaagg gactcaatgt tacccgagta ctttcagaat ttggcgattc
    17881 tgttcttgct actggtttag tgggtggcaa acttggtgag tttttggttg aacatatcga
    17941 taatcaagta aagaaagatt tcttctcaat tcagggagaa actcgtaact gtatcgctat
    18001 tctccacgga gacaaccaaa cagaagttct tgaaaaaggt cctgaagtat tggaacagga
    18061 aggtcaagac tttttggaac atttcaaaaa actcttggag tcagttgaag tagtggccat
    18121 ctcaggtagt ctgccagctg gccttccagt tgattactat gcgagcttgg tagaacttgc
    18181 taatcaagct ggcaagcctg tagtcttgga ctgctcaggt gcagcacttc aggctgttct
    18241 tgaatcaccc cataaaccaa cagtcatcaa accaaataat gaagaattgt ctcagcttct
    18301 tggaagagaa gtttctgagg atttggatga attaaaagaa gtacttcaag aacctttgtt
    18361 tgcagggatt gaatggatta tcgtttcact tggtgccaac ggtacttttg ccaaacatgg
    18421 tgacactttc tacaaggtag atattcctag aattcaggtg gtaaatcctg ttggatctgg
    18481 agactctact gtggcaggaa tttcttcagg acttcttcac aaagaatcgg atgcagaatt
    18541 actcatcaag gcaaatgtcc ttggtatgct caatgctcaa gaaaaaatga ctggtcatgt
    18601 caacatggcc aactatcaag ttctatatga tcaattaata gtaaaagagg tataaaatgg
    18661 ctttaacaga acaaaaacgt gtacgcttag aaaaactttc tgatgaaaat ggtatcatct
    18721 cagctcttgc atttgaccaa cgtggtgctt tgaaacgcct catggctcaa caccaaacag
    18781 aagaaccaac tgtggcccaa atggaagaac ttaaagtctt ggtagcagat gaattgacta
    18841 aatacgcttc atctatgctt cttgaccctg agtatggact tccagcaact aaagctcttg
    18901 atgaaaaagc tggtcttctc cttgcttatg aaaaaacagg ttatgacaca acaagcacaa
    18961 aacgcttgcc agactgcttg gatgtctggt ctgcaaaacg tattaaagaa gaaggtgcag
    19021 atgcagttaa attcttgctt tactatgatg tagatagctc agacgaactc aatcaagaaa
    19081 aacaagccta catcgaacgc atcggttctg agtgtgtggc tgaagatatc ccattcttcc
    19141 ttgaaattct tgcttacgat gaaaaaattg cggatgcagg ttctgtagaa tacgcgaaag
    19201 taaaaccaca caaagttatc ggcgctatga aagtcttttc agacccacgc tttaacattg
    19261 atgtcttgaa agttgaagtt cctgttaaca ttaaatatgt tgaaggcttc gctgaaggtg
    19321 aagtagttta tacacgtgaa gaagcagcag ccttcttcaa agcgcaagat gaagcaacga
    19381 acttgccata catctacttg agtgctggtg tatcagctaa actcttccaa gatactcttg
    19441 tatttgctca tgaatcaggt gcaaacttta acggagttct ttgtggccgt gcaacatggg
    19501 ctggatcagt tgaagcatac atcaaagatg gtgaaacagc agctcgcgaa tggcttcgca
    19561 caactggatt tgaaaacatt gatgagctca acaaagttct tcaaacaaca gcaacttcat
    19621 ggaaagaacg tgtgtaagaa agtcctccta gtttaggaac atgaatctaa aaaaatttaa
    19681 aaaaagttgt atgtaaaggt ttacaaaata acttacttgt gctatactta aatcacaagt
    19741 taatacaagg tgagtgttac taagtaatat taggcatgat cacaggtgaa ttagaaatca
    19801 gctgattttc tagttcattt gtggtcattt tttgtactca tataccttta agatataaaa
    19861 ggaggttgac atgtatcgaa ttctaaatcc aatgaatcac aatgtctcgc ttgtcagaaa
    19921 tgataaggga gaagaggtga ttgtaattgg taaggggatt gcattcggaa agaagaaggg
    19981 ggatttgatt gctgaaaatc atgttgagaa aatctttcgg atgaagaccg aagagtccag
    20041 agaaaacttt atggctcttc tcaaagatgt tccgcttgat tttatcacag tgacctatga
    20101 aatcattgat aagctatcaa agaaatatca ttatccgatt caagagtatc tctatgtaac
    20161 cttgacagat catatttact gttcttatca agctctaact caaggaaggt acaaggatag
    20221 taatctgcca gatatttctg ctaagtatcc tgtcgctttt caaatcgcaa atgaagcttt
    20281 tgaaatttac tgtcagaagc tagcagatca ttttcctgag gacgaaatta ttcggattgc
    20341 ttatcatttc attaatgctg aaggtgaaaa tgaagtggaa cttgtggagt cgattgataa
    20401 gaggaaagaa attctcagga atgttgaaga agttttaacg gactatgcaa ttcaacgaac
    20461 taaaaagaat aaccatttct atgatcgctt tatgatccat ttgaattatt tcttggatta
    20521 tttagacaga tctagagatg ataaccaatc acttctggat atggaagatc atattaaaca
    20581 atcctatcca aaagccttcg agattggttc caagatctat gatgtgatta cgcaacatac
    20641 gggtcttgat ttgtataaaa gtgaacgagt ttatctagtt ctacatatcc aacgtttatt
    20701 gtcataaaaa tttatttaaa actatataag gagaattcta tcatgaatag agaagaagta
    20761 acattgttag gttttgaaat cgtagcctat gctggcgatg ctcgttcaaa actattggaa
    20821 gccttgaagg ctgctgaagc tggtgatttt gaaaaagcgg acgctctggt agaggaagct
    20881 ggtagctgta ttgcagaggc tcaccacgcg caaacaagtc tattgactaa ggaagcttct
    20941 ggtgaggact tagcgtatag tgtgaccatg atgcatggtc aagatcactt gatgacaact
    21001 atcttgttaa aagacctaat gcaccattta attgaacttt acaagagagg agttaaataa
    21061 aatggataag ttaataattt ttattgagaa aggaaagcct ttctttgaga aattatcgag
    21121 aaatatatac ttaagagcga taaaagatgg ttttatttcc agtatgccag cagtattatt
    21181 ctcaagtatt tttatactaa tagctgctgt gcccaatatt tttgggttta aatggtctga
    21241 tgaacagtta gcttttattt tgaaacctta caactactca atggggattt tagctctctt
    21301 agtagctggg acaactgcaa aatcgttaac agattcagtt aatacacgta gtatggagaa
    21361 aaccaaccaa atcaactaca tgtcaacttt tttagcagct gttgttggat tgttaatact
    21421 ggcagctgat ccaattgaag gtggatttgc taatggtctt ttaggtacta gaggattact
    21481 tactgcattt ttggcagctt ttattacagt aaatatctat aaagtatgta ttaaaaataa
    21541 tgtaaccatt agacttcctg aagaggttcc accaaatatt gcacaagttt ttaaagatgt
    21601 tattccgttt gccttatctg ttctttcaat atatggattg gatttaattg ttagaaatat
    21661 ttttggtaca aatgtagcag aatctgttgg taaaatatta gcccctctat tttcagctac
    21721 tgatggttat atcggtttag ctattgtatt tggtgcttat gctttctttt ggtttgttgg
    21781 aattcatggg ccatctgttg tagaaccttt aattgtagct atcagttatg caaatataga
    21841 agctaatgtt cagcttgtgc aagctggtat gcacgcagat aaaattttaa atccagttac
    21901 tcaaactttt gttgtaacaa tgggtggtac tggtgcaaca ctagtagttc catttatgtt
    21961 tatgtggtta tgtaaatcaa aaagaaatag aattgtcgga cgtgcgtctg tagttcctac
    22021 tttctttggc gtaaatgaac caatcctatt tggtgctcca attgttttaa atcctatctt
    22081 ctttattccg tttgttactg ctcctattat caatgtttgg attatgaaat tttttgtaga
    22141 tgttctacaa atgaatagtt tcagtattat tttaccttgg acaacacctg ctccaattgg
    22201 tattgttatg ggaacggcgc tggctccatt gtcattcgtc ttggctataa ctttaatcat
    22261 tatcgacact ttaatctatt atccatttgt taaagtttat gaccatcaaa ttttagaaga
    22321 agaacggaaa ggaaactctt catctgaatt gaaagaaaaa gttgctgcaa acttcaacac
    22381 tgcaaaagcg gatgctattc ttgaaaaagc gggtgtagaa gcagcacaaa atacaatcac
    22441 taaagaaaca aatgtcctcg ttctctgtgc aggtggagga acaagtggtc tccttgcaaa
    22501 tgctttgaat aaggcagcag cagaatacaa tgtccctgtg aaagcagcag caggcggcta
    22561 tggtgctcac cgtgaaatgt taccagagtt tgatcttgtt atccttgccc ctcaagttgc
    22621 ttcaaacttt gaagatatga aagcagaaac agataagctc ggtattaaac tagcgaaaac
    22681 agaaggcgct caatacatca aattaactcg tgatggaaaa ggtgctcttg cattcgtaca
    22741 agcgcaattc gattaaggct agagactctg aaatagtctc ctatcgttac ggaaatcgct
    22801 atggcgaatt tcctattatt aattcgtcgg taaaaagata tcgtttttac ctcctcatgt
    22861 cacaattcgg tgacttggta caagaagtga gatggagaag gatggctcat tgactcctct
    22921 cctctcactt ttactttatt taaatcaaga aataggtgaa aaaaatgaca aaaacacttc
    22981 caaaagactt tatttttggt ggcgcaacag ctgcctatca agcagaaggt gctacacata
    23041 ctgatggtaa aggaccagta gcgtgggata aatatcttga agataactac tggtacactg
    23101 cagaaccagc cagtgatttt tacaatcgat atccagttga cctcaagcta gcagaagagt
    23161 atggtgtcaa tggtattcga atttctattg cttggtcacg tattttcccg actgattacg
    23221 gccaagtaaa tgctaaaggt gttgagtttt atcataattt atttgcagag tgtcacaaac
    23281 gtcatgttga gccttttgta actcttcatc actttgacac gccagaagct ctccactcaa
    23341 atggagactt cttaaaccgt gaaaatatcg aacattttgt agactacgct gccttctgtt
    23401 ttgaagaatt tccagaagta aactattgga caacctttaa tgaaattgga ccaatcggtg
    23461 atggtcaata tttggttggg aaattccctc caggtatcca gtacgacctt gccaaagtct
    23521 ttcaatcaca ccacaatatg atggtgtctc atgcacgcgc ggtaaaattg tacaaagaga
    23581 aaggctataa aggggaaatt ggtgttgttc acgccctgcc aactaaatat cctctagatc
    23641 ctgaaaatcc agcagatgtt cgtgcagctg agttggaaga tatcatccac aataaattca
    23701 tcttagacgc aacttatcta ggtcgctatt cagctgaaac catggaaggt gtcaaccata
    23761 tcttatcagt caatggtggt agcttggatc ttcgtgaaga agattttaca gcattagaag
    23821 ctgcaaaaga cttgaatgat ttcctaggaa tcaactacta tatgagtgac tggatggaag
    23881 cctttgatgg agaaactgaa attatccata atggtaaagg tgaaaaagga agctctaagt
    23941 atcaaatcaa aggtgttggt cgtcgtgtag ctcctgacta tgtaccacgc acggattggg
    24001 attggattat ctaccctcaa ggtttgtatg accaaatcat gcgtgtgaag aaagattatc
    24061 ctaactacaa gaagatttac atcactgaaa atggtctcgg ctataaagat gagttcgttg
    24121 ataacactgt ttacgatgat ggtcgtattg attacgtgaa acaacacttg gagatcttgt
    24181 ctgatgcgat tgcagatgga gctaatgtaa aaggttactt catttggtca ttaatggatg
    24241 tcttctcatg gtcaaacggt tatgagaaac gttatggtct cttctacgta gattttgaaa
    24301 ctcaagaacg ttatcctaag aaatcagctc actggtacaa gaaagtagcg gaaactcaga
    24361 ttatagacta gtagaattag tcattagata tagaatttta gtgagtcaaa aagatgttca
    24421 aagattttat ccaatctatt tatgaaaaaa agtttatatt ataaatttcg aaaaatgctc
    24481 tcaaataccg tgtttgacga gtgaagaatt gaaaagtctt ggaaaatggt atgtctcgac
    24541 tggtaaagaa tggatttgtc attcagatga tgagctggaa gaatttaaaa atctattttt
    24601 aaattttatc aatcctgaag aatgggatac tatctccttt gattcagatt ttatgccgtt
    24661 tcaacaatcg taaccaattt ctcaaaaaag ttaaatctta tatttagtac tctgtaaaac
    24721 tcttatctaa tcacgttgct tatactcaat gaaaatcaaa gagcaacttt aaactaggaa
    24781 gcgagtcgca gatttctcaa tgcatagctt tgaggaattg ggcaaaaagt ctttgatata
    24841 gaaaaaagca tagtatcagg tgttgaaaca cctgatacta tgctttttat tgtgggaaga
    24901 tttacttttt ttcttctgaa attgagttgt tacccaggct ctttcagttt attaaggctt
    24961 gatgacttta atgtgtttag atagcttaaa aaggattgaa tcacttagtt tagaatctga
    25021 a
//
LOCUS       DAVKEV010000033        23633 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVKEV010000033 DAVKEV010000000
VERSION     DAVKEV010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23633
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.033"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(84..233)
                     /locus_tag="VWZ68_001461"
                     /pseudo
     CDS             complement(84..233)
                     /locus_tag="VWZ68_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895229.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(387..2018)
                     /gene="rlmD"
                     /locus_tag="VWZ68_001462"
     CDS             complement(387..2018)
                     /gene="rlmD"
                     /locus_tag="VWZ68_001462"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU9372472.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKIFMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2092..3066)
                     /locus_tag="VWZ68_001463"
     CDS             complement(2092..3066)
                     /locus_tag="VWZ68_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEU9372473.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3140..3754)
                     /gene="pmp23"
                     /locus_tag="VWZ68_001464"
     CDS             complement(3140..3754)
                     /gene="pmp23"
                     /locus_tag="VWZ68_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEU9372474.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(3754..4728)
                     /locus_tag="VWZ68_001465"
     CDS             complement(3754..4728)
                     /locus_tag="VWZ68_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEU9372475.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(4736..5992)
                     /locus_tag="VWZ68_001466"
     CDS             complement(4736..5992)
                     /locus_tag="VWZ68_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEU9372476.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6054..6485)
                     /locus_tag="VWZ68_001467"
     CDS             complement(6054..6485)
                     /locus_tag="VWZ68_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9372477.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSLEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGEGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(6487..7089)
                     /locus_tag="VWZ68_001468"
     CDS             complement(6487..7089)
                     /locus_tag="VWZ68_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEU9372478.1"
                     /translation="MIDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7073..7912)
                     /gene="prmC"
                     /locus_tag="VWZ68_001469"
     CDS             complement(7073..7912)
                     /gene="prmC"
                     /locus_tag="VWZ68_001469"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEU9372479.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASNQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     RQD"
     gene            complement(7912..8991)
                     /gene="prfA"
                     /locus_tag="VWZ68_001470"
     CDS             complement(7912..8991)
                     /gene="prfA"
                     /locus_tag="VWZ68_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEU9372480.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLKELNK"
     gene            complement(9001..9480)
                     /locus_tag="VWZ68_001471"
     CDS             complement(9001..9480)
                     /locus_tag="VWZ68_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9372481.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDVIIGFVMIAYDKKIVISSGNYLLFCFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(9470..10069)
                     /locus_tag="VWZ68_001472"
     CDS             complement(9470..10069)
                     /locus_tag="VWZ68_001472"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEU9372482.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPIMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            10193..10375
                     /locus_tag="VWZ68_001473"
     CDS             10193..10375
                     /locus_tag="VWZ68_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEU9372483.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10512..11885
                     /gene="mnmE"
                     /locus_tag="VWZ68_001474"
     CDS             10512..11885
                     /gene="mnmE"
                     /locus_tag="VWZ68_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEU9372484.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEANLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(11932..12867)
                     /gene="dapA"
                     /locus_tag="VWZ68_001475"
     CDS             complement(11932..12867)
                     /gene="dapA"
                     /locus_tag="VWZ68_001475"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEU9372485.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(12923..13999)
                     /locus_tag="VWZ68_001476"
     CDS             complement(12923..13999)
                     /locus_tag="VWZ68_001476"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEU9372486.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14341..14413)
                     /locus_tag="VWZ68_001477"
     tRNA            complement(14341..14413)
                     /locus_tag="VWZ68_001477"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14378..14380),aa:Thr,seq:ggt)
     gene            complement(14513..15022)
                     /locus_tag="VWZ68_001478"
     CDS             complement(14513..15022)
                     /locus_tag="VWZ68_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEU9372487.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIQKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15020..15116)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15145..15576
                     /locus_tag="VWZ68_001479"
     CDS             15145..15576
                     /locus_tag="VWZ68_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEU9372488.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            15658..16035
                     /gene="mscL"
                     /locus_tag="VWZ68_001480"
     CDS             15658..16035
                     /gene="mscL"
                     /locus_tag="VWZ68_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEU9372489.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16077..17171)
                     /gene="hemH"
                     /locus_tag="VWZ68_001481"
     CDS             complement(16077..17171)
                     /gene="hemH"
                     /locus_tag="VWZ68_001481"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEU9372490.1"
                     /translation="MKKAILMMTFGSPEEISFEGVAEFFTNIRRGVRPQDHEIQTLYD
                     NYIRIGGTPLQRITREEVNLVKERLGEEYGIYFANKFSRPFIPDVIKQMETDGVEECI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEVLLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            complement(17249..18124)
                     /gene="srtG2"
                     /locus_tag="VWZ68_001482"
     CDS             complement(17249..18124)
                     /gene="srtG2"
                     /locus_tag="VWZ68_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG2"
                     /protein_id="HEU9372491.1"
                     /translation="MTVQKRARFKNVFLVFFCVFVALFSWQRVVEASDYDHYNPIEKD
                     ASSTGFETLQHLNKDVCGWISLDGTKVDYPLLQSQDNVKYLDRNAFGDYTIMGSIFLD
                     YRFNPNFTDFNTIIYGHSMASGAMFGEIKKFADKEFFDQHRYGSIYYNGRERGLEIFG
                     ILEVDAYDTEIYRTLSSKDEEHQAYYQYLLSKAKYKRDVSLTSTDKIVLLSTCFLNIT
                     NGRHILLAKITDAPVKVAQDESGEAVGTRYFDHGIPSHWIYILAFLLLIIVLLLLVLI
                     ILIIRRDKKTKEQKK"
     gene            complement(18202..19200)
                     /gene="srtG1"
                     /locus_tag="VWZ68_001483"
     CDS             complement(18202..19200)
                     /gene="srtG1"
                     /locus_tag="VWZ68_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000851047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG1"
                     /protein_id="HEU9372492.1"
                     /translation="MKTKREKPKKSLSRRLVLAVDGVINHLLLIFAALIFLFGFYALW
                     DSNQVYSLASSSEYEAYRPVTTQQDELASFSGFSKLQELNPEVLGWINVYGTNIDYPL
                     VQAKDNEKYLNKDSKGEFAATGAIFLDARNNPKFEDFNTIIYGHHVENGVMFGDVAKF
                     ADQEFFDQHRYGSIYYNGVEKGLEIFEMLEVDAYDFNIYDPGIQGEDRQQAYLDHLLS
                     VAMHKRDISLSPSDRIILLSTCFLDVTNGRHIVVAKITDTVPKNTFHTKKSKPFPYSV
                     FDDSSLGRFLSSIPLWIWYLILFVLFLLLIFLLLVLYLILRRRRESKKNARSRPFY"
     gene            complement(19218..20414)
                     /gene="pitB"
                     /locus_tag="VWZ68_001484"
     CDS             complement(19218..20414)
                     /gene="pitB"
                     /locus_tag="VWZ68_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus major pilin PitB"
                     /protein_id="HEU9372493.1"
                     /translation="MKKTFFKKLFTASIAAITALSVFRGVPTFADDNSAITKANGENN
                     AVVKINKTLNIAEGITTPTATFTFKFTEKTGQSSNGAPYQTGVAIPDRNVEYNKNDHP
                     TADKIQKATEDIFSGVAYGHAGEYVYDVAEAKTGWQAITKNGKTIDAMRYDKRTYEMH
                     VIVKNKVNGGVYISSVYFKENNKSNAPKVEPSEQGVYNLFDNTYTKDASKEPNPDDPS
                     QVDPNAKALTITKKVDGASGDKTRDFQFHIKIQLPSTNKTAETPVTNIIVKHGSKSEV
                     LAVVTPADTVEYNFTLKDGETFTVEQLPAGSKYTVTETGVAGYTDSSIYTTNGAEQTS
                     QGQKNVDFTLTDILIGEKKNDNKVTNKIDDVTPTGLLIDNLPFILMIGLGLAGFVVLS
                     KKRREA"
     gene            complement(20459..21010)
                     /gene="sipA"
                     /locus_tag="VWZ68_001485"
     CDS             complement(20459..21010)
                     /gene="sipA"
                     /locus_tag="VWZ68_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system signal peptidase SipA"
                     /protein_id="HEU9372494.1"
                     /translation="MLLKKKHKKPVTQVNRDKSPPSVWGDILYLVSKLLMVGFVLAIL
                     YFFVFGLLRYNDDGMKPALKDGDLVVYYRLDKRYSIGDLLVYSYKGKERVARVIATEG
                     STIDINENGLIINGSPQQEQDIYKETLLYKEGATFPMKVPAGQLFVLGDNRTTAVDSR
                     AFGTIPIQDTQGKVVTVIRRRGF"
     gene            complement(21010..22770)
                     /locus_tag="VWZ68_001486"
     CDS             complement(21010..22770)
                     /locus_tag="VWZ68_001486"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372495.1"
                     /translation="MIDTPYWFTSGLERGMLNISSLIAPKIDGFYSIKFRYIGSNDSI
                     TSLKGYISGYNSGIPNEIFSANNENDLQQKFKEITDKILPLGVHHVTISDVLSKYVQL
                     LPGDASHLRVVKIKDGNEQELNDNQVTIETKKNEQGLVEVTAKFNPSYTLEDDAKYVL
                     KFTVTSSQEAFDAIAGDKTLTSDDAEEADATKLYSNKGAKVAYSYGIGTSRTKIKDYS
                     EKPTFKPSDPLTVPVEIEWKGVDGKSNPSANRPPSVELNLNQKKDGSIKDSYRKVTSP
                     VQTNSFTENTSFAKVAKGYDYELKAPDAPGYTVEVQKTGTKEKPSFKVIYRQLPSLTV
                     KKILEGEQSPNKSFTINVTLSDKDGKPINGKFGNTTVTNGKAQISLKNSQETALSYLP
                     RDTHYKVEEVENSRTGYHVTYEKQEGTLSEDVQTIVTNHRLPTLSVIKKVTGAFANLL
                     QSFKITINVKDAQNKPLNGSYSAIVNNQKTTLQFTNGKATVDLKKDKTIKILDLPLNA
                     RYSIEEEASSSRGYQVSYDKKEGTLDANKSATVTNNKNSVPETGIDFLSSTLVLGVVL
                     PLGGIFFIILLGHLVVNRRK"
     gene            complement(23092..23595)
                     /locus_tag="VWZ68_001487"
     CDS             complement(23092..23595)
                     /locus_tag="VWZ68_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HEU9372496.1"
                     /translation="MNVQYDFKKIQYFTSSLVIFLAILFLCAPINSLRADSITEPQTT
                     LHKTITPISGQKDQYELSLDITSKLGTETQSEPLDVVLVADLSGSMEERDVWSYSSRR
                     YISRIEALKHTLKGVNGRQGLIDTILSNSQNRLSIVGFAGKIDNQYNDRYYNEYYLSY
                     QYGTWPN"
BASE COUNT         6786 a         4975 c         4428 g         7444 t
ORIGIN      
        1 tgagttttaa actttggtag aagtcttgaa ctccttatat ttacataact atttgcctct
       61 ataactgtta tgacacgaaa ccaacaagca agttcaagca cctccatatc tttattcaaa
      121 tgaggactaa gatattcaca aactttatca taaacctctt tatctttttt cataaaaggg
      181 gcatacaact tagcaaattt atcctaaaat tttttgttgc ctttatcaat catttcaacg
      241 ctcctttaaa tataaaaatg atcctatcaa tctttatatt gagcctattt tctaattgat
      301 accttgcaag aaaggaataa tagctgttcc tataccaagt aggaatgtaa taaatgcaga
      361 aagtcatata ctgtcattct tttctattaa atcattttga agtgtctcaa agcatccatg
      421 atggcttctt ctttttcagg tgtacactgt ggaataattt gtttatcctt tttagacttg
      481 ttgtaatgtt ctcgtaattc tattccacat ttctttttta tctgtgcaat atataatgtc
      541 gaaactttta attcaaattt attccaaaca tattctttga tttgagcata tgttgctttg
      601 ctctccgcac ttgtcaaatc catctcatcc agctcaattt caacacttat gtgcttatcg
      661 acatcaagtt tggacaaaag tgctaccgtc tcgacgtgat gcgtttgagg aaatagatcc
      721 accggctgga ctttcttcaa ttcatatccc aattcttggt agagtttgat atcacgcgcc
      781 atggttgcga cattgcagga gatataggcg atgcgatcgg ctcctgtttg ggcgcttgct
      841 ttgataaagc tttctgtcaa gcccttgcgt ggaggatcaa ccaagataac ggttggttga
      901 atcccatctt taagccaatt cttcatagca ttttcagctg tgtcacagac atagtgggcg
      961 tttgaaatat tgttcagctg agcatttttt ttactattct caaccgcttc tggaatcagt
     1021 tcaacaccgt agacttcttt gacatgcttg gcgactgata aaccaatggt tccaatacca
     1081 gaataagcat caataaccac gtcatctttt tttaactctg caaagtcaat ggctgtttga
     1141 tagagtttct ccgccatttc agtattgact tggtaaaagg ctgggccagc gatttggaag
     1201 tcatttccca acatctggtc cgtaatatag tcttgaccat aaagagtgcg ccactcctta
     1261 ccaaaaatcg cattggtatt ctggtcgttg atattttgca tgacagacac aatctctggg
     1321 aactgcttga taacttgttc aatcaattgg tcaacacgaa aaacttttgg acgagttgtc
     1381 accaaaacga ccatgatttg tcctgaatag tgaccacgac gcaccacaag attccgaatc
     1441 aatccagact gttccttttc gtcataaggt tttaaatcaa aacgacggag caggtctcga
     1501 agagctacta cgacttggtc aatgacagga tcctggataa agaaatcttc aaggggcatg
     1561 aggttatgcg aattcttacg gaaaaatcct gtttccaaga caccattcac tcgacgaacg
     1621 ggcacctgcg ccttattgcg atacttgact ggatgttcca taccaagcgt ttcagcaact
     1681 tctacatctg caattccagc aatcttgtag agactgtcct tgacttgctt ggttttaaac
     1741 ttgagctgtt ctggataaga aaggtgtcct aaatccgcga ttcctgaacg caggtaagcc
     1801 aaatctagat cttgattacg gtgtggtgac tggacaaggt atttttcaac ttttccaaag
     1861 ccaatctttt tattgacctt gaggacacgc atgaaaattt tttcactcgg taaagcattc
     1921 tctacaaaaa agaccaaacc atctaccttg gcaactcctg ccccttcatg ggtcaaatca
     1981 acaatttcaa cttctacaat atcatttttc tttaacattc ttttctcttt ctattggccg
     2041 acaaaaaaga cggcaacgtt acggttacca tccattatac catgaaattt cttaagaacc
     2101 aaaactcttg aagaagttga caagggcttg ccagagggag cttaagaagt taccaccgtc
     2161 ctctagcgcc ttatccgcat caaagttaag gttgatattt ttaaaactgt cgccagcttg
     2221 tgatacgatg ctttgtttaa ggtcatttag ggttttagtg aaatctgcat tgctgaggat
     2281 atcactcttt gagagattca aggcaaaatt gatgatgata ttgatctggt ttcctgttat
     2341 gacctgatca agtttgtaat tttttaaggt atcttcaaca atcttgcgga tatcttcttc
     2401 tgtcagattt cccttgcttt ctttagcttt ggcgagtcct gacttgatat cagctagggc
     2461 aacgtttaat ttattagcat catagcctga tttgtccttg ttttcagcat tgatatctga
     2521 caaagccttt agctcttctt gagccaaatc tttattggct tgcggcacct tggctccatt
     2581 agcttctagc gaatagtaga tcccagccaa agcactctca cctgtaactg gaatgggtgc
     2641 tgctacagtg attttggcgt gttccacacc caaagttacg gctgcatttc ggtacatatc
     2701 ctgagttacc ttagtgatgt tttcaggtgt ttcaatcttg acctcaagtg gcgatttgtc
     2761 acctagcttt tgaatcttgg ctgatgaata caactgtaag ctagagtcat tggccacatt
     2821 catgatttta gaataaacat caggtgtcat ggtcttgagt tctttggtat ctgttgaggc
     2881 attgtagccc agttttttaa gagtttgatt tttttggtct tcagataggg aagaacctag
     2941 gacatattca ggttggacat aggtttcatc gataactttt tgaacatctg ttgctgcatg
     3001 gacgctattc atagctgtta ctgcccacaa gatcgcagcg ctagtcagaa agagtttctt
     3061 tctcataggg aatttcctcc tttacttctt tagagtaata tatctatctt aaagaaaact
     3121 tataacaaaa acacctggtc tagccagatg ttgaaaagag agtgaaacat ttgatgatgt
     3181 aaaggttaag tcgtacctgt ctagaataat aatagtttcc tccatttaca tagagttcag
     3241 caccgtgaaa aatggaaatg gggtgaatat aactataagt ctttccagtc gtattaccaa
     3301 gcaagggggc aacagtctca cgagagtact gtttggctag agccaaggta ttttccttgc
     3361 cattttgggc gataaaatcg atataggcag gtccaaaatt ataggcttga acagctgtcc
     3421 agatatctac acccttcttc tgcgccagat agagattgcc tgtcagagtt tgaatgcctt
     3481 gccgaatgct agaggcatta tcattgatgg tgttggtgga accacttgca gactcactag
     3541 actgcataac atcgccttct tttccttttg tttcagtata aatcatagca agcacaagct
     3601 cttcgtttgc tggggtgtct ttttcactca atatttctcg caccatgggt tgataggtca
     3661 tgacttgttt gacatcttga tgaacgcggt aagctttata gccagcaaaa aggaagactg
     3721 ctagtacaag cactcttcga attcgtttaa acattattta ctttggatat cctcgatatt
     3781 tttgattaag atagagtagg ttccattttc gttttggata aactcaacag actcggcgtc
     3841 ttgatagacg ttattgggaa cgatgagctc aattccattt gataaggaga gtttttggtt
     3901 ttcaaatttc tttaattggc gactggcatc aatttcatca aattgaacag gttctggtac
     3961 ggcttctttg acttggtcaa taaagctcaa acgagccgtc agattgttgt caaaaaggtc
     4021 attagccaat ttctcaggtg acaattcatt gctttcttct aggttgttga aaatagctga
     4081 tttgaccttg gattgaaatt gaaaatcatc tgtgttaaaa gattcagcaa ttctctgggc
     4141 tgttttttcc agttccttga tagatttttt aggagaaatc ttaggagcga cagcaagaag
     4201 attatctgaa aaatagttca aaaaagtccc gttgtacttg attcgttttt caatcaggtg
     4261 atacttgcga ctctgaagat tgaccaccaa ggcctcgtca gcacccgttc caaatccagg
     4321 caggttattc tgagtcagct tgattggatt atcaacttct cctccgaggt gggtcaaggt
     4381 ctcccgcagg gcaattcgca agaaagcgaa atgttctaca ccttctttag aaaattgaac
     4441 aaaaatcaag tcattggtct tgagattttc agaaatgcta aactcctctt tccagagatt
     4501 agccagcgtt actgatgtct ccaacaaatc gtctgtaata tgattgaaga agggattttc
     4561 ttcttcgaaa atcccagtct tggcttcatc tgaatacaca tgttcaattt ttttacgtag
     4621 gtattcttcg atttttggag taatattgag aaacttatct gctaagaaca gctcggtatc
     4681 atccggactg aactggtgaa taatggcttt cttaatataa atgtccataa aagttttatt
     4741 cctcgtataa tgggaaggca tctgtcaatt ctttgactgc acttctcact tcttctaata
     4801 cagcctcatt ttctgaattc ttaagggttt taatgatgag ttcagccact ttgcgacttt
     4861 cttcttcacc aaatccacgt gcagtaatgg ctgctgctcc gatacgaatc ccacttgtct
     4921 tgaatggtga caagctttcg taagggattg agtttttatt taaggtaata ttgacttcat
     4981 ccaacaagtt ttgagcaact ttgccgtttt ctacaacttt agtcacatca acaaggaaga
     5041 gatggttttc agttccacct gaaataatac ggaaatcagg gtcttgcaag aagacatctg
     5101 ccatagcctt gctgttctta attacattgg cagcatattc cttgaaggct ggatccaaaa
     5161 cttctttgaa ggaaactgcc ttagccgcca caacatgctc taaaggaccg ccctgaatac
     5221 ctgggaaaat agctgaattg atttttttag caagttcttc gtcattggtc aaaatcaaac
     5281 caccacgagg accacgaagg gttttgtggg tcgttgttgt tgtgatatga gcgtatggaa
     5341 ctgggcttgg atgaaggcca gccgcaacca aaccagcgat atgggccatg tccaccatga
     5401 gcttcgcacc gacagcatct gcgatttcac ggaattttga aaaatcgata atttgagaat
     5461 atgctgaagc accagctaca atcagttttg gttttacttc ttgggcttgt ttcaagatag
     5521 catcaaagtc taagagttcc gtttcaggat caacactata agaaacaaag ttgtaggttt
     5581 gaccagagaa gctaacagga gccccatgag tcaaatgacc acctgatgcc aaatccattc
     5641 ccataaccgt atcacctggc tcaatcaagg acatgtaagc cgcacagtta gcttggcttc
     5701 ctgaatgtgg ttggacattg gcaaatttag caccgaaaat ttcttttgcg cgttcaatag
     5761 caagagtctc tacaacgtct actacatcag ttccaccata ataacggcgt cctgggtaac
     5821 cctcggcata tttatttgtc aagatagacc cttgagctgc cataacagcc ttggaaacta
     5881 cgttttccga agcaattaac tcgatattat tttgttggcg ttcttcttct ttggcaatag
     5941 cattccagag atcagcatca tatgctttaa aatcatcttt gtcaaaaatc ataggtcttc
     6001 tcctttattg tgtgactagt ccattagttt gattttacaa taagaaaatc aaactaaaag
     6061 atgcgaataa accgtttctg cattttatca caagtatagc caactttttc ataaaatgca
     6121 tgagcaccca gacgatgatt ggcagaattt aagcggataa acccataacc acatcttttg
     6181 gcttcttgtt ccaacccttg tagtaaactt ttaccgatac cttcaccttg cgcttgaggt
     6241 gaaactgcta aagctaagat attaaatcct gctttggaat agagtgattc gtaaacttca
     6301 gcgtggacat atccaagtaa gacatgatta gctgcatcct catagccaag taggaaatga
     6361 tgggaatcct gagacagtct agctagttgg ctagccgttt cctctagact aaaagtataa
     6421 cccaaagcct cttggttgat gtcacatatc gctttcacat ctgtttcttg caaatctctt
     6481 agcatttcaa gcctcctcaa aagaaatctc tggcaaccga gcaagaatat cttctcgttt
     6541 aattgcgcct tggcgtaaga ttttcacctt gtctccagac aaatccacaa tagttgaatc
     6601 ctgtccagtt agaaaagcat cgtcttccag acccagaacc tcttggtcaa aatccttcag
     6661 aatttgttca aaggttacac cacttgcctg acctgagata ttggcagacg gcccaatcaa
     6721 gggacctgtc tctcgaatta aatccagtgt gatagggtga ctgggcatcc gaaatccaat
     6781 agttgcaagg tcagaattta cccaataggg aactcggtca ttggcttcga gaataatggt
     6841 caagggacct ggcaaaaagg tctctacaag tttttgtaga taagttggct gattcttaga
     6901 aaagtgcaag atatcctcga aagaggcgat attgagattg agtgccttat ctctaggacg
     6961 acgtttgagt tggtaaacat ggtcaactgc tttttcatct aaggccttgg caaaaagacc
     7021 ataaacagtc tctgtaggta gaacgacagc tccaccattt tccaactctt gtctaatcct
     7081 gtctatcatc aaccacgacc atcctatttt gaccaaattg gtccttgagt gttcgaactc
     7141 ttttttcagg aagatgtttc ctaaaaagtt cgggaacact ttgaccttgc ttgtatccaa
     7201 tttcaaggta aatcttacca ccatctttga gatagtcttt tgcatcttcc gcaattctac
     7261 agtaaatagc taggccatcc tcgtctgcaa agagagctag atgaggctcc gaatgcaaaa
     7321 cattcaagcc tacctctgac tcatcttcac gagagatata gggtggattg gatacaatta
     7381 tatcatattt ttcagaaatt tctgcaaaac aatcagattt tttaaaaaat atattaagat
     7441 tttgattgct agcattctct gatgcaagct ctaaggcctc ttgagaaaca tctgctgctg
     7501 tcactgacca atctggtcta ttttttgcta gagcgagagc aatagctcca ctacctgttc
     7561 caatatccag aactgaaaga ttcgtctcaa gattttcagt tagaataagc tccactaact
     7621 cctctgtttc tggacgagga atcaaaaccc gttcatccac ctttaaatgc attccataaa
     7681 aatctgcctg tccaatgatg tactgagctg gcttgtgagc tgctagttgc tggtaaatat
     7741 cttctacaaa ttgtttttct tcctctgttg tcacctcctg ctggagggca aaaataaagt
     7801 ctgtaaaaga tagatttttc agactacgat agacaaaaga gaggctttcc gcttcctctc
     7861 cttgtcttat caactcttct tcaaaatttg aaaataattg agctaatttc attatttgtt
     7921 taattctttt agtttttgtg tttggtcata aagcaccaag gcatccacaa cttcgtccaa
     7981 tttaccagac aaaatcgtat ctagtttttg gagggtcaag ccgatacggt ggtctgtgac
     8041 acggttttgt gggaagttat aagttcggat ccgttctgaa cggtcaccag taccgattgt
     8101 cgacttacgc tcagcgtctt gttcatcctg agcaatctga gcaaagtggt cagcgacgcg
     8161 tgcacggata atcttcatag ccttctcgcg gttcttctgc tgggtacgtt cttcctgcat
     8221 ctcaaccttg atattggttg gcaagtgaac gatacgaacg gcagtcgcaa ccttattgac
     8281 gttctgtcca ccagcaccag aggcgtgata gatgtcgaca cgaaggtctt ttggatcaat
     8341 gtcgtattca acctcttcaa cttctggcat aacaagaact gtcgctgtcg aagtatgaac
     8401 acggccttgg ctttctgtca caggaacacg ttgcacacgg tgggcacctg attcatactt
     8461 aagcttagag tatacagact gacctgaaac catagcaacc acttctttaa aaccaccgac
     8521 accattcata gaggcttcca tgacttcaaa gcgccaacct tgggcttccg catacttttg
     8581 gtacatagtt agcaaatctc cagcgaaaag tgccgcttcg tctccaccag ctgctccacg
     8641 gatttcaagg atgatattct tgtcatcgtt tggatccttt ggaaggagca aaattttcag
     8701 tttttcttca tattcttctt tttcagcctt ggcatctttg agttcttgct tggccatttc
     8761 ttccaagtcc gcatctccgc ctgattcctt aatcatctct tcggcatcga cgatattttg
     8821 aaggacttgt ttatactcac ggtaggctat tacggtgtca cgattggaag cttcttcttt
     8881 tgaaagctcc ataaaacgct tggtgtctga aacgacatca gggtcactca gcaattctcc
     8941 tagttcttca taacggtctt ctacagcttg tagttgatca tagatgttca ttttttctcc
     9001 ttatttctca attgttaaat catagattgc tactacttca ttctcggata tttccccagt
     9061 ttctttaaat ccataactga gataacaaaa tcttgcctgt tcattttctg gttcataaga
     9121 caaccaaagt ttattgctta aacctgctgg cgctgttcga acatagtcta gtactttatc
     9181 cataattggt ttaaaatatc cttgattttg aaaattctta tcaatcataa aacaaaatag
     9241 taaataattt ccactactaa ttacgatctt tttatcataa gctatcatca caaaacctat
     9301 aattacatca ttatcataaa ctgccaatgg agctacaaaa tctccatttt tagtgtagac
     9361 gtatgcttca gctaaactaa ttgcgttggt tgcaatgaat tgtttttgat attccttgac
     9421 atccaaattt aaaacatcaa aataattttc cattgtaaca tctcttagtt caattgtcat
     9481 agttttgctc cttgttagag gttatcattg gcgcaaaata atgtttacgg caaaccgaga
     9541 tataggtttc attaccacca atctggatct gttctccatc gtaaacgggc agtccatcct
     9601 gtgttcgcaa caccatggtc gcctttttct tgcaatactg acagatggtc ttgatttcgt
     9661 caatcttgtc tgctaaaagc aagagatatt tggaaccttc gaacaattca ttgcgaaagt
     9721 catttttcaa accaaaagcc atgatgggta tgtctaactc gtccacaaca cgagctaggt
     9781 cgtaaacatg gtggcgttta agaaactggg cttcatcgac caaaacacag taaggttttt
     9841 ctggtaggtc tcggatatag ccaaagatat ccgttgtttc ctcaatcgca agggcagggc
     9901 gtttcatgcc aattcgactc gacacatagc caacaccgtc acgcgtatcc agagccgagg
     9961 tcataatgac aacacctttt ccttgctcct catagttata ggccaccttg agaatctcga
    10021 ttgtctttcc agagttcatg gtcccataac gataatacaa ctgtgccatg tttcttgctt
    10081 cacgtccatt tctaaatttt tgctacattc tagtatatca taattttctt aagctttaaa
    10141 cggcaaaatg tggtaaaata gaagaaatca aaaactagtg gaggaagcta ttatgccatt
    10201 tgtacgcatc gatttatttg aaggacgcac gctcgagcaa aagaaagctc ttgctaagga
    10261 agtaacggaa gcggttgttc gcaacactgg agcacctcaa tctgctgtcc atgtcatcat
    10321 caacgacatg ccagaaggaa cttacttccc acaaggggaa atgcgtacca aataagctag
    10381 cttaagcaga attgcttagg ctttttcaat ctccaagtag cattcattga agaaatatcc
    10441 taaatttgtt acaatttgaa aagaaacttg gagaatttcc aagaaaatag ctattaatta
    10501 aaggaaacat tatgattaca cgtgaatttg ataccatcgc tgctatctct actccactag
    10561 gtgaaggggc tattggtatt gtccgcctga gcggaacaga cagttttgct attgcgcaaa
    10621 agatttttaa aggaaaagac ttgaacaagg ttgccagcca cactctcaac tacggtcaca
    10681 ttattgatcc tctgactggt aaagtcatgg acgaggttat ggttggggct atgaagtctc
    10741 caaagacctt cactcgtgag gatattatcg agattaacac ccacggtggt attgcggtga
    10801 ccaatgagat tctccagcta gctatccgtg aaggagctcg gttggcagaa cctggtgaat
    10861 ttaccaaacg tgccttttta aacggtcgcg tagatttgac acaggccgag gcggtgatgg
    10921 atatcatccg cgccaagaca gacaaggcca tgaacatcgc ggtcaaacaa cttgatggtt
    10981 ccctttctga tcttatcaat aatatccgtc aagaaatcct taacacactt gcccaagttg
    11041 aggtcaatat cgactatcct gagtatgacg atgttgagga agccactact gctgttgtcc
    11101 gagagaagac aatggagttt gagcaattac taaccaagct ccttaggaca gcacgtcgtg
    11161 gtaaaatcct tcgtgaagga atttcaacgg ctatcattgg acgtcccaac gttgggaaat
    11221 caagccttct caacaacctc ttgcgtgagg acaaggctat cgtaaccgat atcgctggga
    11281 caacacgaga tgtcatcgaa gagtacgtca acatcaatgg tgtacctctc aaattgattg
    11341 atacagctgg tattcgtgaa acggatgata tagtggaaca aatcggtgtt gagcgttcga
    11401 aaaaagccct caaggaagcc aacttggttc tactagtgct aaatgccagt gaaccactga
    11461 ctgcgcaaga cagacaactt cttgaaatta gccaagatac caatcgcatt attctactta
    11521 ataaaaccga cctgccagaa acgattgaaa cttcgaaact acctgaagac gttatccgta
    11581 tttcagtcct taaaaaccaa aacatcgaca agattgaaga gcgaatcaac aacctcttct
    11641 ttgaaaatgc tggcttgatt gagcaagatg ctacttactt gtcaaacgcc cgtcacattt
    11701 ccctgattga aaaagcagtt gaaagcctac aagccgttaa tcaaggtctt gagctgggga
    11761 tgccagttga tttgcttcaa gttgacttga ctcgtacttg ggaaatcctc ggagaaatca
    11821 ctggggatgc tgctccagat gaactcatca cccaactctt tagccaattc tgtttaggaa
    11881 aataagaaaa atccatgatc cttcattcgg tcatggattt tattgtcttt attagtaatc
    11941 tggtcttaag acccctgtta cagttgcctt agttgcttcg tagtcgccat ctacgacaac
    12001 cttgataatg cgtttggcat cttcttctgg tgctggaaca agaggtagac gagtgggtcc
    12061 agcttcaaat cccatatagt taagaattgc cttaactgga gcaggacttg gataagagaa
    12121 gagagcatta accttaggaa tgaatttacg ctgaattgct gcggctttct tcatatcgct
    12181 ttctgcaatg gcagtaaaca tctcgtgcat ttcatcccca tttgtatgag aggcaacaga
    12241 aataacccca tccgccccaa ggttcatggc atggaaagca tctccatcct cacctgtata
    12301 aatcaagaac tcttcaggct tgtgctcaat caagtaagcc atattagcca agctagtaca
    12361 ttctttgaca ccgataatat ttggatggtc agccaagcga agcatggttt ctggagtcaa
    12421 ttcgacaact acacgccctg gaatgttata gataataatt ggtaggtcag aagcatctgc
    12481 aatagtctta aagtgctgat acatcccttc ttgagaaggt ttgttgtagt aaggaacaat
    12541 agcaagccca gctgcgaaac caccaaattc cgctacttct ttgacaaact caatagagtc
    12601 acgcgtatca ttagtaccta cacccgcaat caaaggaacg cgtccattga caaccttttg
    12661 tacagccgca aacaactcca actcctcatc gtgggtcaaa gttggactct cagcagtcgt
    12721 tcctgcgaga agaattccat ccgtatgatg ggccaataaa tgctcaatca aggctggaat
    12781 agcatcaaag ttaatagaac catcctcatg aaagggggta ataaaggctg taatgatttt
    12841 acattctttt aaatcttgat aagacatgaa aacacctctc tatttcaaag aaggagttca
    12901 tctgaactcc taaacgatat gactatttta attcaaattt caattcggct gttggacgaa
    12961 ccaatccacg ttcatgaaga gtttcagcaa tctgaactga gttccaagca gcacctttga
    13021 gaaggttatc tgaaacaacc cacatgtgaa ttcctttttc tgcatccaag tctttacgga
    13081 tacgaccaac aaaggtatca cgcgaaccaa ctgcattgat agcttgagga tagatttgat
    13141 gagctacatc atcttcaaga acagcacctg ggaaggctgc gatagctgct tttacttctt
    13201 cgattggagc cacttctttt gtttcgatat aaacagactc agagtgagct gacaagactg
    13261 gaatacgcac acatgttgca gatactgcaa tgctatcatc ttccataatt ttcttagttt
    13321 ccttggtcat cttcatctct tcgtacgtgt aatcattatc agtgaaaaca tcaatttgtg
    13381 gaagagcgtt aaaggcgata ggataatgtt tcttgtcacc acctgaaggc aaaatttccg
    13441 catgcaaatc acatggtttc acaccatcat tcaagacttc acgaagttca cgttgtgtct
    13501 caagaattgc tcccatacca gcacctgaaa cggcttgata agttgaaaca atgatacggt
    13561 ccaagcccca tttttggcga accggctcaa gagccaccat catttggatt gttgaacaat
    13621 tagggcaggc aatgattccg ttgtgggcat caagtgcatg agcattgacc tctggaacaa
    13681 ccaaaggaac atctggattt tgacggaaat aagatgtatt atccactact accacgccag
    13741 cttttactgc gtatggtgca tacttagctg atgtagaact acctgctgaa aagagagcaa
    13801 tatcaactcc ttcaaaagct gtttcagtcg tttcttcaat tgtaatatct tgatctttaa
    13861 atttcaatga cttacctgct gaacgtgcag aagcaaggta acggatttta tcgattggaa
    13921 gtgttgattc ttccaacatt tttatcatct gagcaccgac agcacctgtc gcgccgacta
    13981 cagcaactgt atatcccata aataacctct ttcggaattt tctaaaaatt tctataatag
    14041 aagtattata ctactttttc catgaattgc aaagcttttt catcattttt tggaaaataa
    14101 aaatcccagt cgctagacta gggactaaga ggcatcttca tgtgatgagc aggttcacac
    14161 aactcatcaa ggtccgctcc tgcgttatga cctccttatg ctcaatagta gtccgaagac
    14221 tacctatcga ctcatcgcat attctatatt actagagata cttgattttg tcaataagaa
    14281 attttttcga tcgagtataa caaaaaactc tcgtattcaa gagtttccct atacatatca
    14341 tgctaattgc cgggatcgaa ccggcgacct catccttacc atggatgcgc tctgccaact
    14401 gagctaaatc agcttactta agaagtatac tatattcaga aaaacttgtc aagtttcctt
    14461 agaaattttc cataggaaaa agccaggtaa gaactaccta gcttatcttc ttctatttac
    14521 ttaaatcaat tcgacgacca attttaccaa taataatcgc cccaataatc aatgaagcaa
    14581 attcaccgat tcctgttgta aaccaagtaa ggaagaatgg taattctgct acaatattta
    14641 actctgcagc gatagtaaac atggaaattg aaaagaggat tgaaaagaag aaatgatctt
    14701 tttgaatcaa tccgttaaag aggtaatcct tgctatattt tgcaaaaagc caaacaccta
    14761 aactgaggaa tactaaggtt gaaccaccac caacaaagac atctagcagt ccgaagctaa
    14821 agaaattagc aatcatacaa ccgatggtaa ctccgatgat gtacttagga ttgtaaaaag
    14881 ccataaagtt catcatttct gaaatacgaa actgataagc accatagctg atggcattta
    14941 ggggcggtgt gacagtcaaa acgacgtaga tagcagcgac gattgcaata tctgcaacat
    15001 cacgaatagt taattttttc atcttttctc ctttggcggt tgcccgcgtg taatatgctt
    15061 ggtgaaagaa gctaagcacc aagggttgct ttattcaacc ctactagtat agcacaatag
    15121 cctgctttat gctatactta acacatgaaa attcctattc aaaaattttt taacaatgaa
    15181 atcttagcct atctcttttt tggccttgcg acaactctag tttcgattct ctcacgacta
    15241 gtcatttatc aactaagtca tcaggaactc ctggctactg ccctagcaaa tattatcggt
    15301 atcctatttg cctttatcac aaatgatacg attgtattta agcaaaaaaa gaaaaataga
    15361 cttatccgtt tagtgaaatt ttctcttgct cgcctttcta cttttctgtt agacttgttt
    15421 ttaacttttc tctttgtaac ccaatttcct cacattatag ggcaattcgt aactgaaaac
    15481 attgataaga taaatgctat tgaaacaata attgcacaaa tattcattat tatcatcaat
    15541 tatatattga gcaaggccta tatttttaga aaataatgct ccatttatga gccttttaat
    15601 tgccttctat aatgatttag gatacaatga aacacgaaac attgaaagga aaacagtatg
    15661 ttaaaaaatc taaaatcgtt cttgcttcga ggaaatgtta ttgaccttgc tgtcggtgtt
    15721 gtaattgcct ctgcttttgg tgctatcgtt acttcacttg taaacgacat tatcactcct
    15781 cttattttaa atcccgcttt gaaagctgct aaagttgaac gtatcgctca actttcttgg
    15841 catggagtcg gctatggtaa cttcttaagt gctattatca attttatctt tgtgggtacc
    15901 gccctcttct ttattatcaa gggcattgaa aaagcacaga aactgactgg cataaagaaa
    15961 gaaaaaactg ccgaaaaaaa accaaccgaa ttggaagtcc ttcaagaaat aaaagctctc
    16021 cttgagaaaa aataatcgat taaaaggatc tagcgcaaag ctaaatcctt ttttctttac
    16081 tctttgggta acttgcctgc tttttcaagc atttttttga tcagataagg catcttaaca
    16141 ttctcccgcc cttttttctc aatcagtttt ttcacaaatt ctggcatttg taaatcttca
    16201 gattcagcta aaatgttttt cgtctcgtct gaaggaacta actcatcaaa ggtctcttct
    16261 tctgggagaa attccttaaa ctcttgattt tcattgactc taactgtatt gaccaaagca
    16321 tcaatcaaac gagaatctgt atttggcatt ggtggacgat ggtagtttac cccaaattcc
    16381 tggcataagt cataacattc tacatcattg tcaaacaaga cctcaatatg ctcactgatg
    16441 aaactaatag gtacaaaaat ataatggtct ggatgttctg tctgttctct gagatactcc
    16501 aaaacatctg gtttaatcca tggaatacca atatcactct cactctgcca agtgttggta
    16561 tattgttctg aactcaagcc cagtttttca gcgactagct tgctattttc gaaaatttgg
    16621 tctatataag gatcaccaaa gtccaaggca aaaatgggca cactatgggc tgaaaagatg
    16681 actttaaagc tgtcttgctt tacttcttct tttaaaatct tagcaatttc atctgcccaa
    16741 tagtttaaga gcacttcttc ctgataccag tccttaatga ccaaaaattg aatttgtttg
    16801 ctttctaaaa atttttcata gcccatgaca gagtagaaag aataatgggg ctccaaaatc
    16861 aagcagatac attcttcaac accatcagtt tccatctgct tgatcacgtc tggaataaag
    16921 ggacgagaaa atttgttggc aaagtagata ccgtactcct cccctaaacg ttctttgact
    16981 aaattgacct cctcacgtgt aatccgctgc aaaggcgtcc caccgatacg aatatagttg
    17041 tcatagagag tctggatttc gtggtcttgg ggtctaactc cacgacgaat gtttgtaaag
    17101 aattctgcta ctccttcaaa actaatctcc tctggagatc caaaggtcat cattaatatg
    17161 gcttttttca tgttatcatc cttatgatat tattttctct atccattcta tcatgaaaga
    17221 aaaaaatagt aaacgtttcc tacgtctact atttcttttg ctcttttgtt tttttatctc
    17281 gtcttataat taggatgata aggacaagaa gtaagaggac gataataagg agtagaaagg
    17341 ctagaatgta aatccaatga ctgggaattc cgtgatcgaa ataccgtgtt cctactgctt
    17401 ccccactttc atcctgtgct actttcaccg gtgcatccgt tattttagct aaaaggatat
    17461 gtcgtccatt agttatgtta aggaaacagg tgcttaataa aacaatcttg tccgttgagg
    17521 tcaaggaaac atctcgcttg tacttggctt tacttagcag atattgatag taagcctggt
    17581 gttcctcatc cttggaactc aaggttcgat aaatctccgt gtcataggca tccacttcta
    17641 aaatcccaaa aatttcaaga ccacgttctc gaccattgta gtagatagaa ccgtagcgat
    17701 gctggtcgaa gaattcctta tcagcaaatt tcttaatctc accgaacata gcccctgaag
    17761 ccatagagtg tccgtagatg atcgtattaa aatcagtaaa gttgggatta aagcgatagt
    17821 cgagaaaaat tgatcccatt atcgtataat cgccaaaggc attgcggtca aggtatttga
    17881 cattatcctg actttgtaga agcggatagt ctaccttggt cccatcaagg ctaatccaac
    17941 cgcaaacatc tttgttcaag tgctgtaggg tttcaaaacc tgtgctcgaa gcatcctttt
    18001 caataggatt atagtgatca tagtcacttg cttctactac tctctgccaa ctaaaaagag
    18061 ctacaaaaac acagaagaat accagaaata cgtttttaaa tcgcgctctt ttttgaaccg
    18121 tcatcagcac tcctttctat gcgagatttc ttaaaaggaa aggaggcggg acaaaaccgc
    18181 ctcttttcta ttcaccctta gtcagtaaaa gggtctgctt cttgcatttt ttttactctc
    18241 tcttctacga cgtaggatca agtagaggac aaggagtaag aaaatcaaga gcaagaacaa
    18301 tacaaacaag ataaggtacc aaatccatag tgggattgat gagaggaaac gtccaagaga
    18361 cgagtcatca aagacactgt atggaaatgg ttttgatttt tttgtatgga aagtattttt
    18421 agggacggtg tctgtaatct ttgcgactac gatatgacga ccattggtca catcgagaaa
    18481 acaggtactg agtaggatga tacgatcact cggtgagagt gagatatccc gcttgtgcat
    18541 ggcgactgag agcaggtggt ctagataggc ctgctggcgg tcctcaccct gtattcctgg
    18601 atcatagatg ttaaagtcat aggcatcaac ctccaacatc tcaaagatct cgagcccttt
    18661 ttccacacca ttgtagtata tactaccgta acgatgctgg tcaaaaaatt cctgatcagc
    18721 aaacttagcc acatcaccaa acatgacccc attttctacg tggtgcccgt agataatggt
    18781 attaaagtct tcgaacttag gattatttcg tgcatcgaga aagatagcgc ctgtcgctgc
    18841 aaactcacct ttggagtcct tgttgagata cttttcattg tccttggctt ggactaaggg
    18901 atagtcgata ttggtgccat agacattgat ccaaccgagg acttcgggat tgagttcttg
    18961 gagtttgctg aagcctgaaa aactggccag ctcatcctgt tgcgtcgtga caggtcgata
    19021 agcttcgtac tcacttgacg aagctaagga gtagacttgg ttggaatccc aaagggcgta
    19081 gaaaccaaag agaaagatca aagctgcaaa aatgagcagc aagtgattga tcaccccatc
    19141 cacagcaaga acgagacgcc tagacagact cttttttggt ttctcacgct tggttttcat
    19201 catctgcccc cagccgttta ggcttctcta cgttttttag acaagacaac aaatccagcc
    19261 aaaccaagac caatcatcaa aatgaatgga aggttatcaa tcaagagacc agtaggagta
    19321 acgtcgtcga ttttgttagt aactttgttg tcgtttttct tttcacctat gaggatatct
    19381 gttaatgtaa aatctacatt tttttgtcct tgagatgttt gttctgcacc atttgtagta
    19441 taaattgatg aatctgtata acctgctact ccagtttcag ttactgtata tttagaacct
    19501 gctggtagtt gttcaactgt aaatgtttca ccatctttaa gagtaaaatt gtactcaact
    19561 gtatctgctg gggtcactac tgccaacacc tctgacttag atccatgttt tactataata
    19621 ttcgtaacag gggtttctgc tgttttattt gtacttggaa gttgaatctt gatatggaat
    19681 tggaaatctc ttgttttatc ccctgaagct ccatcaactt ttttagtaat tgttaatgct
    19741 ttcgcattgg ggtctacttg actcggatca tcaggattag gctccttact tgcgtctttg
    19801 gtatatgtgt tatcaaataa attataaacg ccttgttcac ttggttctac tttaggggcg
    19861 ttagatttat tattttcctt aaagtatact gatgaaatat agacaccacc atttacttta
    19921 ttcttaacaa taacgtgcat ttcatatgta cgtttgtcgt atctcatggc atcaattgtt
    19981 ttaccatttt tggtaatcgc ctgccatcca gtttttgctt ccgctacatc ataaacgtat
    20041 tcaccagcat ggccataagc aactcccgaa aaaatgtctt ctgttgcttt ttgaatctta
    20101 tcagcagttg ggtgatcatt tttattgtat tctacatttc tatctggaat tgcaactccg
    20161 gtttgatatg gcgcaccgtt agaagattgt cctgtttttt ctgtaaactt aaatgtaaat
    20221 gtcgctgttg gtgttgttat tccctctgca atattcaacg ttttattaat cttcacaaca
    20281 gcattatttt caccatttgc tttggttatt gctgaattat catccgcaaa agtcgggaca
    20341 cctctgaata cggacaaagc ggttatagct gcaatgcttg cagtgaatag ctttttaaag
    20401 aatgtttttt tcatgattat ttcttttgtt tttttatttt cttttttcat tatgatcatc
    20461 aaaagcctcg tcttctaatg actgttacaa ctttgccttg agtatcctgt atagggatgg
    20521 ttccaaaagc acgactgtct acagccgttg ttcgattgtc cccgaggaca aaaagttgtc
    20581 ctgctgggac tttcatcggg aaggttgccc cttccttata gagcagcgtt tctttgtaga
    20641 tatcttgctc ttgttgagga gaaccgttga tgatgagacc attttcgttt atatcgattg
    20701 tacttccttc ggttgctatg acacgcgcca ctctttcctt acctttataa ctatagacta
    20761 gcaaatcacc aatcgaatag cgtttatcca acctataata gacgaccaag tcgccatctt
    20821 ttaaggcggg cttcatgcca tcgtcattgt atcttaataa tccaaagacg aaaaagtaaa
    20881 ggatggctag tacaaatcca accatcagaa gtttactgac taagtaaagg atatctcccc
    20941 agacactcgg cggagactta tcccgattga cttgtgttac tggtttctta tgtttctttt
    21001 taagcagcat cacttcctcc tattcaccac aaggtgacca agtaagatga taaagaagat
    21061 ccctcctaga ggaagaacga ctccaagcac gagagtgcta ctcaagaagt caattcccgt
    21121 ttcaggtacg ctgtttttat tattcgtgac tgtcgcagac ttatttgcat caagagttcc
    21181 ttctttttta tcataggaca cctgataccc acgagacgaa cttgcttctt cttcgatact
    21241 ataacgagca tttagaggaa ggtcgagaat cttgatggtt ttatctttct ttagatcaac
    21301 tgtcgcctta ccattggtga attgtagcgt tgttttttga ttatttacta ttgcactata
    21361 cgatccattc aatggtttat tttgcgcatc ctttacgtta atggtaatct taaaggattg
    21421 cagaagatta gcaaaagcac ctgtaacttt ttttatgact gaaagtgtcg gaagtctgtg
    21481 gttggtgacg attgtttgaa catcctctga caaagtcccc tcttgttttt cataggtgac
    21541 atgatatccc gttctagagt tctctacttc ttccacctta tagtgggtat cacgaggcag
    21601 ataactgagg gcagtttcct gactattttt gagagaaatc tgtgctttcc cgttagtcac
    21661 tgttgtattc ccaaacttgc cgttaatcgg cttgccatcc ttatctgaaa gggtaacatt
    21721 aattgtgaaa gatttattag gtgattgttc accttctagg attttcttta cggtgagact
    21781 tggaagctgt cggtaaataa ctttgaagga tggtttctct ttcgtacctg tcttttgaac
    21841 ttcgactgtg tatcccggag cgtctggtgc tttcagttcg tagtcatatc ccttagctac
    21901 ctttgcaaaa ctagtatttt cagtaaaact attcgtttga actggactag tgacctttcg
    21961 ataggaatcc tttatacttc catctttctt ttggtttaag tttaattcga cactaggtgg
    22021 acgatttgct gatggatttg attttccatc cacacctttc cactcaatct ctacaggaac
    22081 cgtcaatgga tctgacggct tgaaagtggg cttctcagaa tagtctttta ttttggtacg
    22141 tgaggtccca ataccatagg aataggcaac ttttgccccc ttgttggagt agagtttagt
    22201 agcatcggct tcttcggcat catcactagt aagtgtctta tcacccgcaa tcgcatcaaa
    22261 tgcctcttgg ctagaggtga cagtaaactt gagaacgtac ttggcgtcat cctctaaagt
    22321 gtaactcgga ttaaacttgg ctgttacttc cactaatccc tgttcgttct tcttagtttc
    22381 aatcgtaact tgattgtcat tcagttcttg ctcgttacca tccttgattt tgacgacacg
    22441 aaggtgtgaa gcatcaccag gtaacagctg cacgtacttg gacaagacat ctgatatagt
    22501 tacatggtgt acgcctagag gtagaatttt atctgtgatt tctttgaatt tttgttgcaa
    22561 gtcattttca ttattggcag aaaatatttc gttggggatt ccagaattat aaccactgat
    22621 atatccttta agagatgtga tactatcgtt tgaacctata tatctgaatt tgattgaata
    22681 aaagccatct atttttggag ctattaaact agatatattc agcattcctc tctctaaacc
    22741 agaggtaaac caatatggag tatcaatcat acgtcccaca tttggattag aataatagtt
    22801 atatattgtt ctcccactat tagactcgta atacatatta gcttcgccat ctgacagcag
    22861 aataactact ttttttgccc cagcccttgc actttgcaac aatctttgag cttcagttaa
    22921 cccagcattt atatttgtcc cagtgccaat gcccgcgtcc ataccataag aacgactaga
    22981 gtcagcaatt gttaacgaac taacaatatt ttttgagcta ttagaatccg tgctccaaga
    23041 tactaaagtt ttagcatcat catatgaaga gatatttgaa taccaaccag ctcaatttgg
    23101 ccaagttcca tattgataac tcagataata ttcattataa taacggtcat tatactgatt
    23161 atcaatcttt ccggcaaaac caactataga cagacggttt tgggaattag aaagaattgt
    23221 atcaatgagc ccctgacgac cattcacacc tttcagtgta tgttttagtg cttcaatcct
    23281 actaatgtat cgtctactag agtaagacca cacatctcgc tcttccatac tccctgaaag
    23341 atcggcaacc aagactacat ccaagggttc tgactgggtc tccgttccca gtttagatgt
    23401 gatatccagt gacaactcat actggtcttt ttgccctgat atcggagtaa tcgttttgtg
    23461 cagagttgtc tgaggttcag ttattgaatc tgcacgtaaa gaattaattg gtgcacacaa
    23521 aaaaagaata gcgagaaaga taactaaact actggtaaaa tattgaatct tcttaaaatc
    23581 atattgaacg ttcatgctat ctcccttgct agaatatgtt ttaatctgat act
//
LOCUS       DAVKEV010000034        23125 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVKEV010000034 DAVKEV010000000
VERSION     DAVKEV010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23125
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.034"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            169..1650
                     /locus_tag="VWZ68_001488"
     CDS             169..1650
                     /locus_tag="VWZ68_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9372497.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2012..3013
                     /locus_tag="VWZ68_001489"
     CDS             2012..3013
                     /locus_tag="VWZ68_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9372498.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3164..4081
                     /locus_tag="VWZ68_001490"
     CDS             3164..4081
                     /locus_tag="VWZ68_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9372499.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4092..4982
                     /locus_tag="VWZ68_001491"
     CDS             4092..4982
                     /locus_tag="VWZ68_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9372500.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            5011..6627
                     /locus_tag="VWZ68_001492"
     CDS             5011..6627
                     /locus_tag="VWZ68_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9372501.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6637..7956
                     /locus_tag="VWZ68_001493"
     CDS             6637..7956
                     /locus_tag="VWZ68_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU9372502.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8166..8238)
                     /locus_tag="VWZ68_001494"
     tRNA            complement(8166..8238)
                     /locus_tag="VWZ68_001494"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8203..8205),aa:Lys,seq:ctt)
     gene            complement(8503..9774)
                     /locus_tag="VWZ68_001495"
     CDS             complement(8503..9774)
                     /locus_tag="VWZ68_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEU9372503.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            10044..10244
                     /locus_tag="VWZ68_001496"
     CDS             10044..10244
                     /locus_tag="VWZ68_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372504.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            10448..10627
                     /locus_tag="VWZ68_001497"
     CDS             10448..10627
                     /locus_tag="VWZ68_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372505.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10764..10943
                     /locus_tag="VWZ68_001498"
     CDS             10764..10943
                     /locus_tag="VWZ68_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEU9372506.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            10980..11432
                     /locus_tag="VWZ68_001499"
     CDS             10980..11432
                     /locus_tag="VWZ68_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEU9372507.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11723..12193
                     /locus_tag="VWZ68_001500"
     CDS             11723..12193
                     /locus_tag="VWZ68_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEU9372508.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            12212..13300
                     /locus_tag="VWZ68_001501"
     CDS             12212..13300
                     /locus_tag="VWZ68_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEU9372509.1"
                     /translation="MKKIGTYLVYVLAFVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            13281..13439
                     /locus_tag="VWZ68_001502"
     CDS             13281..13439
                     /locus_tag="VWZ68_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
                     /protein_id="HEU9372510.1"
                     /translation="MELEISDFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     KSVRENLI"
     gene            13549..14583
                     /locus_tag="VWZ68_001503"
     CDS             13549..14583
                     /locus_tag="VWZ68_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU9372511.1"
                     /translation="MKKSDVLDLIKYHYEGRETEFRNQSIAIARNFNKHGDTQIAQYI
                     MGLMSQSDRFMPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFL
                     FVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQ
                     NYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKA
                     VTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPG
                     DLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGISK
                     SSVSRELSED"
     gene            14645..16828
                     /locus_tag="VWZ68_001504"
     CDS             14645..16828
                     /locus_tag="VWZ68_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HEU9372512.1"
                     /translation="MGPITIPKKTIITLEHLKYLHFSLEETKTYWEKNNIIDGILISI
                     YYNRIVAKSNRINGYFNVGGGNPFPNDTIVGAKFNDEKTKHIVTHYISRDALNKTITV
                     LSKIIEVFEEHFDRAITCEMFSDSSTFASINFSEYGISKSKFQQYLRDSCFIENFGVE
                     HTTVSDIQNSIVTFYDVHTDIFRLLNKLNIDISEANIMNQTTVLLDEKNIELLLSKAP
                     YLVSMIVEDFSKLSVDDFSLDNNDLKINLPSPMNEPVVGVIDTLFDKRVYFNEWVEYH
                     DFVSPDISKDSQDYKHGTAVTSLIVDGANLNPNLDDGCGNFRVRHFGVSLQSGFNSFT
                     IIKQIKEIVSQNADIKVWNLSLGSNDEIRENFISAEGALLDEIQFENDVIFIIAGTNA
                     SVINGKRKRIGAPADSLNSIIVNSVDFNNQSVSYSREGIVLSFFVKPDVSYYGGGNGD
                     FINVCEPLGLGRVAGTSFAAPFIARKMAYLIHIMGLSREEAKALLIDAAIPWNDKKTF
                     TDLSLIGNGIVPIKMDDILSTPDDEIKFIVSDISRAYDTYNYDFPVPISSESYPYVAK
                     ATMCYFPNCSRKQGVDYTNTEMQLTFGRLKSDGIKSINKDNQHAEDTPGYVRENAARN
                     IFRKWDNVKHIGESFTSRKRAKAILNPSNPQWGMSIKTIERLKSGDGQGVRFGVVVTL
                     KELNGVNRIEDFIQQAELRGWLVNRLQVEAQVDLFNSLNEEIEFE"
     gene            16879..17895
                     /locus_tag="VWZ68_001505"
     CDS             16879..17895
                     /locus_tag="VWZ68_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU9372513.1"
                     /translation="MNITYIVGNGLDLQYGLKTRYRDFYEFQNKVYISRTENEEKYSN
                     FIYESLFSDKVNDYENWSDFELSIGKLTKDNDLISSSIEIKEKFIDDFSEVVDDLREY
                     LRIQQEKNLEKGNAIDFISTLDDMRTSLPVINQPAIDKKYNENPHQDDIVNIVTLNYT
                     HVIDKLYNGSAKSFRNQLRANLYNFYIEPPIHAHGTVDVCTVLGVSDEIQISNSLEEQ
                     KESLIKSLVLKNYRENMDVKNSDIIKNSDIIILYGVSLGETDRYIWSQIAERSISGSV
                     PVIIYHYVPHFDPGNPIRAKRLYRNVEDKFIQNSGIDLELEKKLRDNLIVVIGKTIFD
                     LIER"
     gene            17910..18860
                     /locus_tag="VWZ68_001506"
     CDS             17910..18860
                     /locus_tag="VWZ68_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEU9372514.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTVLA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEMIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRESAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            18862..19605
                     /locus_tag="VWZ68_001507"
     CDS             18862..19605
                     /locus_tag="VWZ68_001507"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEU9372515.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            19616..21412
                     /gene="pepF"
                     /locus_tag="VWZ68_001508"
     CDS             19616..21412
                     /gene="pepF"
                     /locus_tag="VWZ68_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU9372516.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PIAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            21659..22213
                     /locus_tag="VWZ68_001509"
     CDS             21659..22213
                     /locus_tag="VWZ68_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEU9372517.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLSNQGL
                     HYLSKEKDTTGFSSQYGWVHAFAHGADLLTEVVCHPDFPKNRVHEVFDILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDELKEAIQSFQY"
     gene            22324..22992
                     /locus_tag="VWZ68_001510"
     CDS             22324..22992
                     /locus_tag="VWZ68_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEU9372518.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT         7340 a         3799 c         4892 g         7094 t
ORIGIN      
        1 gccctcaata gacggtaaaa taagaaaatt gtttatatat tgtctccgta gtgttattat
       61 acgaaataaa agattttagg aaaagtcgtt atatcatgct atacctattc tttgtggtat
      121 aattgcaaga ggtttaatcc gataatttat aaagagagaa agatattcat gagagattta
      181 ttatctaaaa aaagtcatag gcaattagaa ttattagaat tattatttga acataaacgt
      241 tggtttcatc gttctgaact agcagagtta ttaaattgta cagaacgtgc agtcaaagat
      301 gatctatccc atgttaaatc tgcttttcct gacttgattt ttcattcttc tactaatggt
      361 atacgcatta ttaataccga tgatagtgat attgaaatgg tttaccatca tttctttaaa
      421 cattcaactc atttttcgat tttagaattc atcttcttta atgaaggttg tcaagctgag
      481 agtatttgta aagaatttta tatcagttca tcttcgctct atcgtattat tagccaaatc
      541 aataaagtga ttaaaaggca atttcaattt gaagtcagtc tgacccctgt tcaaatcatt
      601 ggaaatgaga gagacattcg ttactttttt gcacaatatt tttcagaaaa atattatttc
      661 ctagaatggc catttgaaaa tttttcatca gagccactat ctcaattgtt agaattggtt
      721 tataaggaaa caagctttcc aatgaatttg tcaacgcata gaatgctaaa gttgctccta
      781 gttacgaacc tatatagaat aaagtttggt cattttatgg aagtagataa agattctttt
      841 aacgaccaaa gtttggattt tttaatgcag gcagaaggaa tagaaggtgt tgctcagagt
      901 tttgaatcag aatacaatat ctctttagat gaagaagttg tttgccaatt atttgtgtct
      961 tactttcaaa aaatgttttt catagatgaa agtctcttta tgaaatgcgt aaaaaaggat
     1021 agttatgttg aaaaatctta ccatctattg agtgatttta ttgatcagat ttcagtcaag
     1081 tatcagattg aaatggagaa taaggataat ctgatttggc atctgcataa taccgcacat
     1141 ctgtatcgtc aagagttgtt tactgagttt attttatttg atcaaaaagg gaatacaatc
     1201 aggaactttc aaaatatttt tccaaaattt gtttcagata taaaaaaaga gctttctcac
     1261 tatttagaga ctcttgaggt ttgttctagt tcaatgatgg taaatcatct atcttatacc
     1321 ttcatcactc ataccaaaca tttggtgatt aatttgctac aaaatcagcc taaactaaag
     1381 gttttagtta tgagtaattt tgatcagtat catgcaaaat tcgttgcaga gacactttct
     1441 tattactgta gcaataattt tgaactggaa gtttggactg aattagaatt atcaaaggaa
     1501 tctttagaag attcacctta tgatatcatt atttctaatt ttattattcc tcctattgaa
     1561 aataagagac tcatctattc aaataatata aacacggtct cactcatata cttgttaaat
     1621 gccatgatgt ttattcgatt agatgagtaa ccaaaaataa caaaaaaacg ctatttcgcg
     1681 tttgaactgt acctcaaaag ttagacagaa aaaatctaat ttttggggtg tttttgttaa
     1741 gaaaagacct tcaatcattt aagcaaaatg tacatctaga tttatagccc tctaaaactc
     1801 ttgctttttt tgtagaagat acgaaaaaag ccataaaacc aaggcttttc ctgttttatg
     1861 tagatgttta cacatgaaaa ttgaagtatt ttcaaaagct aattggagtg attttattca
     1921 tgatgggata aatgatctgg ccaaaaatga ttgagaaata gttgcttaaa aagcatttgc
     1981 atgatactat atattgaaag gaggtgataa tatggtagaa caaagaaaat caattaccat
     2041 gaaagatgtt gctttagaag caggagttag tgttggaact gtttcacgtg taattaataa
     2101 agaaaaaggc attaaagaag taactttgaa aaaagtggaa caagcgatta aaactttgaa
     2161 ttacattcca gattactatg ctagaggaat gaaaaaaaat cgaacagaaa cgattgcaat
     2221 cattgtacca agtatctggc atcccttctt ttcagaattt gctatgcatg tggaaaatga
     2281 agtctataag agaaataaca aattactctt atgttctata aatggtacaa atagagagca
     2341 agactatctg gagatgttgc gtcataataa agttgatgga gtggttgcca ttacctatag
     2401 tccaattgaa cattacttga cgtcaggaat tccctttgtt agtattgacc gcacatactc
     2461 agatattgcc attccttgtg tttcatcaga taatgatgca ggtggaagag aagcagctaa
     2521 acaattaatt agtaaaggat gtcagcattt agcctttgtg ggcggacata atacaaccat
     2581 taatgaaacc aaacgtcgta gaatttcatt tgaaaagtat gtccaagagc ataaaatacc
     2641 tcttagtatt tttgatttgg atgagacagt tactgactat tatggaaagc tagagagttt
     2701 cttggaagaa aattcttcta tagatggaat ttttacaatc aacgatttta cagctttgga
     2761 tgtgattgaa atactagaaa aaaatggcaa acgtattcct catgatgtcc aaattattgg
     2821 atacgatgga attaaaatgg ctggagatag agattatcta ctttcaacta ttgaacaacc
     2881 attggaagaa atggcaaaag aagcggttcg tattttgttt gatataattg atggaaagac
     2941 tgttaatttg cagacaatcc taccagtaaa atttgttgaa ggaaaaacaa caaaaaatga
     3001 aaataagtct tgacagaaag cgctatcaat gatagaatga attcagataa aaagatttat
     3061 ttttaaaaca aaaatgaaac gtttcaaaaa aagaaataaa aagacagcgc caagcgctat
     3121 cttttataga aaaaatgaaa cgtttcaaaa aaaggaggtt gctatgaata gcaaagcgaa
     3181 gcaagtttct ctttgggaaa gaatcaagaa acaaaaactc ttgttattga tgactgtccc
     3241 cggtttagtt ttaaccttta tctttaaata catccctatg tatggggttt taatcgcatt
     3301 taaagattac aatcctttaa aaggaatttt agggagtgat tggattggtt tttctgagtt
     3361 tacaaaattc atatcctctc ccaactttgg tatcttgtta gccaacacat taaaattaag
     3421 tatctatggt ttattgcttg gctttttacc accaatcatt cttgcgatta tgctcaatca
     3481 actcttgagt gaaaaagtca aaaaacgaat tcagctcatt ttatacgcac caaactttat
     3541 ctcagtcgtt gttattgtcg gtatgatttt cctcttcttt tcagtgggag gaccaatcaa
     3601 caattttctt tctatgtttg gaatgaaggc tgacttcttg acaaatccag acttctttag
     3661 acccttatac atctttagtg gtatctggca aggaatgggc tgggcttcaa cgctctacac
     3721 ggcaacattg gtaaatgtag atccagcctt agtagaagca gctcgactgg atggagccaa
     3781 tatcttccaa cgaatctggc acattgatat tccagctctt aagcctatta tggttatcca
     3841 atttgtttta gctgcaggtg gaattatgaa tgtcggatat gaaaaagcat tcttgatgca
     3901 gacatcgtta aatttgccaa cttctgaaat tatctcgaca tatgtctata aagttggtct
     3961 tgtatcagga gactattctt actcaacagc ggttggtttg tttaatgcag tgattaacgt
     4021 agtattgctt gttgcagtta accaaatcgt taaacgcatg aataatggtg aaggaattta
     4081 aggaggaaag tatgaaaaat tcgattatgg atacaaaatt tgatagacgt atcttactct
     4141 taaataaaat cattattgtc tttatcgttt tgatgacttt gcttccttta ctttatatcg
     4201 tcgtagcatc ctttatggat cctaaggttc tggttagtag agggattagc tttaatccag
     4261 ccgattggac tgtagaaggt taccagcgtg tattcagtga ccaatctatt ctaagaggtt
     4321 ttatcaattc tctactatac tcttttggat ttgcagcttt aacagtattg ctatctgtgt
     4381 ttacagctta tcctctttct aagaaagact tggttggacg tcgttggatt aactacttct
     4441 tgattgtgac tatgttcttt ggtggtggtt tagtcccaac ttacttgctc gtaaaagaat
     4501 tgggaatgct caatactcca tgggctatca ttgttccagg tgctgtcaat gtttggaata
     4561 ttattcttgc tagggcctat ttccaaggat tgcctgaaga attagttgaa gctgctgtca
     4621 ttgatggagc gaatgacttg cagattttct ttaaaatcat gcttcctctt gcaaaaccaa
     4681 ttatgtttgt tctcttcctc tatgcttttg taggacagtg gaactcatac tttgatgcaa
     4741 tgatttatat caaggatcca aacttggaac cattgcaact tgtacttcgt aaaattctca
     4801 ttcagagcca accaggtcaa gacatgattg gagcacaagc ggctatgaat gaaatgaaac
     4861 gtttagctga attgattaaa tacgcaacta ttgtcatttc cagcttgcca ttgattgtta
     4921 tgtatccatt cttccaaaaa tactttgata aaggaattat ggctggttca cttaaaggat
     4981 aaaaaaagaa aaaataaaag gagttttctc atgaaattca aaacattctc aaaatcagca
     5041 gttttgttga cagctagttt agcagtactt gcagcctgtg gctcaaaaaa tacagcttca
     5101 agtccagatt ataagttgga aggtgtaaca ttcccgcttc aagaaaagaa aacattgaag
     5161 tttatgacag ccagttcacc gttatctcct aaagacccaa atgaaaagtt aattttgcaa
     5221 cgtttggaga aggaaactgg cgttcatatt gactggacca actaccaatc cgactttgca
     5281 gaaaaacgta acttggatat ttctagtggt gatttaccag atgctatcca caacgacgga
     5341 gcttcagatg tggacttgat gaactgggct aaaaaaggtg ttattattcc agttgaagat
     5401 ttgattgata aatacatgcc aaatcttaag aaaattttgg atgagaaacc agagtacaag
     5461 gccttgatga cagcacctga tgggcacatt tactcattcc catggattga agagcttgga
     5521 gatggtaaag agtctattca cagcgtcaac gatatggctt ggattaacaa agattggctt
     5581 aagaaacttg gtcttgaaat gccaaaaact actgatgatt tgattaaagt cctagaagct
     5641 ttcaaaaacg gggatccaaa tggaaatgga gaggctgatg aaattccatt ttcatttatt
     5701 agtggtaacg gaaacgaaga ttttaaattc ctatttgctg catttggtat aggggataac
     5761 gatgatcatt tagtagtagg aaatgatggc aaagttgact tcacagcaga taacgataac
     5821 tataaagaag gtgtcaaatt tatccgtcaa ttgcaagaaa aaggcctgat tgataaagaa
     5881 gctttcgaac atgattggaa tagttacatt gctaaaggtc atgatcagaa atttggtgtt
     5941 tactttacat gggataagaa taatgttact ggaagtaacg aaagttatga tgttttacca
     6001 gtacttgctg gaccaagtgg tcaaaaacac gtagctcgta caaacggtat gggatttgca
     6061 cgtgacaaga tggttattac cagtgtaaac aaaaacctag aattgacagc taaatggatt
     6121 gatgcacaat acgctccact ccaatctgtg caaaataact ggggaactta cggagatgac
     6181 aaacaacaaa acatctttga attggatcaa gcgtcaaata gtctaaaaca cttaccacta
     6241 aacggaactg caccagcaga acttcgtcaa aagactgaag taggaggacc actagctatc
     6301 ctagattcat actatggtaa agtaacaacc atgcctgatg atgccaaatg gcgtttggat
     6361 cttatcaaag aatattatgt tccttacatg agcaatgaca ataactatcc aagagtcttt
     6421 atgacacagg aagatttgga caaaattgcc catatcgaag cagatatgaa tgactatatc
     6481 taccgtaaac gtgctgaatg gattgtaaat ggcaatattg atactgagtg ggatgattac
     6541 aagaaagaac ttgaaaaata cggactttct gattacctcg ctattaaaca aaaatactac
     6601 gaccaatacc aagcaaacaa aaactagagg ttgattatgg gagataagaa atacacagta
     6661 gaaaaagcca atcgttttat agcagaaaat aaacatctcg ttaatactca atataagcct
     6721 gaagaacatt tttcagctga gattggttgg atcaatgatc caaatggatt tgtctatttt
     6781 cgtggagaat accatctctt ttatcaattc tatccatatg atagtgtttg ggggcctatg
     6841 cactggggac atgctaaaag taaggacttg gtgacttggg agcacttgcc agtggcactt
     6901 gctcctgacc aagattatga ccgaaatggt tgtttctcag gctctgccat tgtcaaggat
     6961 gatcgcctct ggctcatgta cactggacat atcgaagaag aaaccggtgt ccgccaagtg
     7021 caaaatatgg cattttcaga tgacgggatt cactttgaaa agatttccca aaatccagtt
     7081 gcaactggat cagacttgcc agatgagttg attgctgctg atttccgtga tccaaaactc
     7141 tttgaaaaag atggacgcta ttactccgta gtagctgcca aacataagga taatgtgggc
     7201 tgtatcgttc tactagggtc cgataaccta gtagaatggc agttcgaatc catcttttta
     7261 aaaggggtag aacaccaagg ctttatgtgg gaatgcccag attacttcga gttagatggg
     7321 aaagattgcc ttattatgtc acccatgcgt tatcagcgtg agggagactc atatcataac
     7381 atcaactcat cgcttttgtt cacgggtaag gtagattggg gagaaaaatg ttttatccca
     7441 gaatcagttc aagaaattga tcatggccaa gacttctatg cgcctcaaac attgttggac
     7501 gatcaaaatc gtcgtatcct gattgcttgg atgcagacat gggggcgtac ccttccaacc
     7561 catgaccaag aacacaaatg ggcatgtgcc atgactttac ctagaatttt aagattggaa
     7621 gatggcaaac taagacaatt ccctgttaaa aaaggccaat atcaaatcca aatagataaa
     7681 gattgtcatt accacttagg aaatgatata gattatcttg aatttggtta tgatagtaat
     7741 gcgcagcaag tttacattga tcgtagccat cttattcaaa aaattctagg tgaagaagaa
     7801 caggacacta gtcgacggta tgtagatatt gaagctaaag aattggaagt tgttctagat
     7861 aaaaattcca tcgagatttt tgtcaatcaa ggtgaagcaa gcttgactgc aacttattac
     7921 ttaacggtgc cagctgagct atcacgaatt gattaaaaat taagttattt ctcctaaaga
     7981 aaaagttctc tttctaaaat agtggaaaga ggactttttg tgttttgggt atataagctt
     8041 agtttatggt atttgtaaaa ttggtgttgg attatgattt aagctagttt tctaaagaat
     8101 ttgaaaaaaa ttttatttaa gcaaaaaaaa cccttggttc caaggctttt cctgttgtat
     8161 ttatatgccc cctacaggga tcgaacctgt gacccacgga ttaagagtcc gctgctctgc
     8221 cagctgagct aaggaggcaa agaaaaaagc tgtattggtg ccgaaacttc acggtttgta
     8281 ttgaacccgc gcaattaagc aggtgggcaa ctcgctctaa ctgaagctgt ttccgtgtga
     8341 gacggcctac atgctgttag aagacttttg tttccctaat aatacaaaaa atagtcggtc
     8401 aacacttaag tgtgaagtcg tacaccacag cgtttctata cttatatgat accacttttt
     8461 caaaaaaaat caagaggaaa gtgcaatttt ttgaaaagga tttcagattt ttcgcaaacg
     8521 gtcgatagct tcctttcttt gagccaaagc ccgttcatat ttaccagtat cttctgcttg
     8581 gaaatagtga tgattacgaa ttttttctgg cagatagtct tgcttgaccc aatttccagg
     8641 atagttgtgt ggatagagat agtcttgggc attccccagt tccttgcttc cactgtagtg
     8701 cccatcacgt aggtgtcgcg gaataggcaa gtgccctgat gttttgaggt cagcaagtgc
     8761 cttatccata gctacatagg ctgagttgga ttttggagaa agggccaaat caatcacgac
     8821 attggcaatg agaatgcggg cttctgggaa cccaatcttc tgggcagcat ccagagcagt
     8881 cacggtatga atctgggcct caggattggc taagccgata tcttcatagg cgataacagt
     8941 caagcgacga gcgagactag gcagatcccc agcctcaatc aagcgggcag tatagtggag
     9001 actggcatcc acatctgagc cacgaataga cttttgcagg gcagatagaa catcatagtg
     9061 accgtctcca tccttgtcca tagtgatgta gcttctctga agactatttt ccatgatgtc
     9121 taaggtgatg tggcgaatgc cctcgtcatt ctcaggggta gagagaacag ctaagtccag
     9181 tgagttaaag gcagagcgaa ggtctccgtt tgtagaggtt gcgatgaaat ccagcgcatc
     9241 ctcatctagt tctattggaa aatcaaaacc acgttcaggg ttacttagag ctatctgcag
     9301 ggcctctttg acgtcttggt tagacagagg ttccaactcg aaaatttgaa ctcggctacg
     9361 aatggcagga gtgacagaga agaaaggatt ttcagtcgtt gctccaatca tgatgaccag
     9421 tccactttcc aagagaggca agaggaagtc ttgcttggtc ttatctagtc gatgaatttc
     9481 gtctagcaat aggacgagac caccagaaaa tttagcttct tccgagattt cttgcagtcg
     9541 ctttttacta tcaactgtcg cattgaaagt tcgaaaggca tacttggtcg ttccagcgat
     9601 ggcagaggca atactggttt tgccgattcc aggagggcca tatagaatca tggaggacag
     9661 gcggttggct tccaccatgc ggcggatgat ttttccaggt ccgaccagat gctcctgacc
     9721 gatgacctgg tcgatggttt tagggcgcat gcgaagcgcg agattgtctg gcatagcagt
     9781 cctttctagc gtggatttga gtagaatgac tcatctacta tatcttacta tgtccattct
     9841 agcctattag ttgtgatatt tcaatggttt tgtaataatc agggagtgag atagaatctt
     9901 ttttactatt taatttaatg aggagaggta tcagcatgag agatttgatt ttccttaaag
     9961 ctcaaaatag gatagttgag cctaaagaag tggaagtgct gacttgagaa ataatattgc
    10021 tgaatgtcat tgtatgaact ataatgaaaa gagaggtgat aagtaatgga aatgatggac
    10081 caagtcagga aattttgatt tttacaaaac aaattcgtca ttggattctt agtgatcaag
    10141 ttatttcagg gaaaagaaaa cttttcttcc gggaagatac tccaaaagag attttagatt
    10201 tgtacgaaaa cattaaatct aaacttgatt ttgcttacca ataagtttat tctaataatg
    10261 ggttgaaaaa atatgaaaaa tagaataatt gatgtttttg aagtagtaaa tcgcatcctt
    10321 gtaataactg ttgaaaatcc tgatttcgaa gacttgagag ttaatcatac tcaatgaaaa
    10381 tcaaagagca aactaggaaa ctagccgcag gctgtacttg agtacggtaa ggcgacgttg
    10441 acgtggtttg aatttgattt tcgaagagta tcagtttgta aaaattggag ataaaaaata
    10501 tagagtacgc agtgttccta tgattcattc aactccgcct caatctgtct tagatcgaga
    10561 tacttttaca attgactata cagatgatga attgctcgat aaagaagcag tttttactac
    10621 tcattagaaa aataggtctg aataaattgg cttcccttag aaccacatct aggggctttt
    10681 atgtataata gaataataag tatcactcct ttacaatacg tgtaacacgt gttataatgg
    10741 tgttgtcagg aggtaaaagc gctatgccta tgacacaaaa agagatggtt aaactcctta
    10801 cggcccatgg ttggataaag actagaggcg gtaaaggctc ccatattaaa atggagaagc
    10861 aaggggaaag acttatcaca atccctcatg gtgagctgaa taagtacact gaaagaggga
    10921 taagaaagca agctgggttg taaaattcag cccctgtttt ttgatatgga ggtagtgaaa
    10981 tgttagttac gtatccagct ttattttatt atgacgacac agacggaaca gaagcgactt
    11041 attttgtcca tttcccagat tttgaatact cagctacaca aggagagggg atttctgagg
    11101 ctttggctat ggggtcggag tggctaggga taactgttgc agatttgata gagagtgatg
    11161 gagagttacc tcagccatca gatatcaata gcttgtcttt aattgataat gatcctttta
    11221 aagatgatga agatttcgtg tcaacctatg accttgataa atcttttatt tctatggtat
    11281 ctgttgatgt atcagaatac ctaggaagtc aggaacccat aaaaaagact ttgaccatac
    11341 caaaatgggc agataagttg ggacgagaaa tgggacttaa cttttctcag actttgacag
    11401 acgctattgc agataagaaa gttcaagcct aagattaagc gtggtatcgt ggtaatagtc
    11461 aataaaaaag cacgtccact tgtgctagtt actcgcctat tgattttata gatttattag
    11521 ccctttcgcg ggctttttat attgattttt atgagaaatg aagaaatcag acttttaaga
    11581 aaatcactga taccaagggt ttaaatgagg taatatggta taattaggac ataaaataat
    11641 tttgtggtaa gatggtagta tctattttag catatttccg agcaatcggg gcgattaaag
    11701 agtcgcatag aaagaggaca aaatggcaac atacggattt ttagatgttt tagaggaaga
    11761 gttggacaag aactttccct ttgactttga gattagctgg gacaaacgca accatgcggt
    11821 agaagtgagt tttctattgg aagcgcaaaa tgctgcaggt gtggagatgg tggatgaaga
    11881 cggagaggtt ttatcagatg acattctttt tgaggaagcg gtccttttct acaatcctgc
    11941 caagtcaaca gtcaatgagg aagactattt gactgttatt ccttacctgc ctaaaaaagg
    12001 attttcccgt gaatttttag cttattttgc gcttttcctt aaagatactg ctgaggttgg
    12061 gctagatgtc ctcatggact ttttggaaga cccagaagca gaggaatttg tcatggaatg
    12121 gaaccaagaa gtctttgaag aaggaaaagt tggcttggaa gagggagaat tttatcctta
    12181 tccaagatac taggagttgg ttggaggtgt tatgaagaaa attgggactt atttggttta
    12241 tgtgctagct tttgtcttta ttatgctagc ttttgcttgt ggaacaatcg catttgcaga
    12301 gttggggtat tccgcagttt tagcctttac ttttggttat gccttcgctc ttctaagcat
    12361 gtatttaatc tttattcttc atgagctggg tcatgctttt tgtggctact tgacaggcta
    12421 tcggctggtg gcttttggat taggacattt tattttgacc aaaaagtcag gcaggtttca
    12481 tcttagtaga acagccattc tgaaaaatgt tggtgctcaa tacattggtt taaaagagga
    12541 tgaaagcgat caaagaatca tcctgatgct ttcaggaggc ttgatggttc atctcggctt
    12601 gatattattg gcgatagtgt ttggattttt gacaagaagc tggtattttg cagggacttg
    12661 gatttttctt aatttatctt tcttcctaaa taacattttg ccagtcgaca tcaccgatgg
    12721 agcaaaaatt tgggaattac tacaacaccc tgaaaatacc aaatacgcct acctggtatt
    12781 gagacattct gctcaaactt tgctggctcc tcaagaatat gatttgaaag actttgttca
    12841 agcagttcct gaggatgcac gagggagttt tgcggatggt gtattaggta tgcaaggtga
    12901 agtttccatt ttggaaggga aggaagaagt agctaaacag cagtttcaag cattacttga
    12961 gaggacaact actccgatga tgcagacagt tgcccaacta tccctgcttc atatcgcctt
    13021 gttggaagga gattttgagc aagcggagca atatgctagt attcgacagg tcaaatcgtt
    13081 tctgtctctc aaactgtcca atcttcaagt gatacaagct tggtatcaat ttaaggtaaa
    13141 gaaagatgta gatcgaactc gtaaggctct caagattgct agacagaaaa tggatagtag
    13201 tcgaatgttg agggacgaga aacgctatta tgaaaacttg ttagcagagc tggaaaagga
    13261 aatgttagaa ggaactgaag atggaactag aaatttctga tttcccaggc tgtaagattg
    13321 ctttgttttg tggggataag ctcttgacta tcttacgtga tgataaggca agtattccct
    13381 gggccaatat gtgggaactg ccaggtggtg gaaagagtgt cagggaaaat ctgatatagt
    13441 tttgtattaa aagaatatcc tttcaaggtt attctttttt aattttgtcc caaaataatt
    13501 gactttgtcc cgaaaatata gtattatttg tgtaaggagg aatgaatcat gaaaaaatca
    13561 gatgttcttg atttaataaa gtatcattat gagggcagag agacagaatt tagaaatcaa
    13621 tccatagcaa ttgctcggaa cttcaataaa catggtgata cacaaatagc acaatatatt
    13681 atggggttaa tgtctcaaag tgatagattc atgccacaaa tagaaaatcc tagtgagtat
    13741 ttgactcctg ctaaactaga tattggtcct ctcccattgc ctctttcaat tatgaatgat
    13801 ttaaaaggaa taataaacgc tgtcaatcat catattggaa taaataaatt tttatttgtg
    13861 ggatctccag gtactggaaa aactgaaagt gtaaagcagg tggctagact tattggcaag
    13921 gaattacttg tagtagattt cagtcactta gtagatagta agctagggca aacagtcaaa
    13981 aacttagcaa ctctttttaa tgaaatcaat aatcttcctt tcaagcaaaa ttatatcatc
    14041 ctatttgatg aaattgattc catagtgttg gatagggtta atcagaatga tttaagagaa
    14101 atgggacgag tgacttctgc ctttttaaag gagttggata ggctgtcacc agaaattgta
    14161 ttaattgcaa caacaaatct ttttgaaaat cttgataaag cagttacgag aagattcgat
    14221 gccataattg actttgaccg ttatactgat gaagataaag tagaagtagc tactattatt
    14281 ttaaatgagt tattaaagca atttaagaat gtagctagag atttaaaatt atttaaaaaa
    14341 attatcaata gtgccaatgt aataccgaat cctggtgatt tgagaaactc aataagaacg
    14401 tcattggcat ttagtgaccc atcagatccg catgattacc aaaaacgcct gctaagaagt
    14461 ttgcataatg gtagaaattt atctatttct aaattatcga agctaggttt tactgttaga
    14521 gaaattgaga ttttgacagg tatttctaag agtagtgtat cacgagagtt aagcgaggat
    14581 taaaatgaat acattattga cattacgagg taaaagtttt acacaaaaat caagaaataa
    14641 tggtatggga ccaataacta tacccaaaaa aacaataatt acattggaac atttgaagta
    14701 tcttcatttt tcattagaag agacgaaaac atattgggag aaaaataaca ttatcgatgg
    14761 tattttgatc agtatttact ataatcgaat tgttgccaaa agtaaccgta ttaatggcta
    14821 tttcaatgta ggaggaggga atccattccc taatgatact attgtgggag caaaattcaa
    14881 tgatgagaag acaaaacata ttgttactca ttatatttct agagatgctc ttaataaaac
    14941 aataaccgtt ttaagtaaga taattgaagt ttttgaggaa cattttgata gagcgataac
    15001 atgtgagatg ttttctgatt catcaacgtt tgcttctata aatttttcgg agtatggtat
    15061 ttcaaaaagc aaatttcaac agtatttgag agattcttgc tttattgaga attttggagt
    15121 tgagcacact actgtttctg atattcaaaa ttctatcgtg acattttatg atgtccatac
    15181 agacattttt agattactga ataaattaaa tattgatatt tcagaagcta atatcatgaa
    15241 tcagaccacg gtcttgcttg atgaaaaaaa tattgaattg ctactatcaa aagcgcccta
    15301 tcttgtctcc atgattgtgg aagatttttc taagttatct gtagatgatt tttctttaga
    15361 taataatgat ttaaaaataa atcttccatc tccaatgaac gaaccagttg ttggcgttat
    15421 tgatacctta tttgacaaaa gagtttactt taatgagtgg gtagaatatc atgattttgt
    15481 ctcacctgat attagcaaag atagccaaga ttacaagcat gggacagctg tgacttcttt
    15541 aatcgttgat ggagccaatt tgaaccctaa tctggatgat ggttgtggaa attttagagt
    15601 gaggcatttt ggtgtgtcac tacaaagtgg atttaattca tttacaatca taaaacagat
    15661 aaaagagatt gtttctcaga atgctgatat taaggtttgg aatctttctt tagggtccaa
    15721 tgatgaaata agagaaaatt ttatctctgc agagggagca ttattagacg aaattcaatt
    15781 tgagaatgat gtaattttta tcatagctgg gacaaatgct tcagtaataa atgggaaacg
    15841 caaaagaata ggtgctcctg ctgattcact taattctata atagtaaatt ctgttgattt
    15901 taataatcaa tcagtgtcat attcacgaga gggtattgtt ttatcattct ttgttaaacc
    15961 agatgtgtca tattatggag gaggaaatgg tgactttata aatgtttgtg aacctctagg
    16021 attaggtcgt gtagctggaa caagttttgc ggcacctttt attgcaagga aaatggccta
    16081 tctcattcat attatgggac ttagccgaga agaagcgaag gctttgctaa ttgatgcagc
    16141 aataccctgg aatgataaga aaacattcac tgatttatct ttgataggaa atggtattgt
    16201 tccaataaaa atggatgata ttttatctac acctgatgat gaaattaaat ttattgtgtc
    16261 agatatctct agggcttatg atacctataa ttatgatttt ccagtaccta tttctagtga
    16321 gagttatcca tatgtagcta aagcaacaat gtgttatttc cctaactgct caagaaaaca
    16381 aggggttgat tatacaaata ctgagatgca gcttactttt ggtaggttaa agtcagacgg
    16441 tatcaaatcg ataaataaag acaaccagca tgccgaagat accccaggat atgtgagaga
    16501 aaacgctgct agaaatatat ttaggaaatg ggataatgtc aagcatattg gagagtcgtt
    16561 tacttctcga aagagagcta aagcaatttt aaatccatct aatcctcagt gggggatgag
    16621 tattaaaaca atcgaacgtt tgaaaagcgg tgatggacaa ggagtacgtt ttggtgtagt
    16681 agttacatta aaagaattaa atggggttaa tcgtattgaa gattttattc agcaagctga
    16741 attacgcggt tggctagtta atagattgca agtagaagct caagtagacc tctttaatag
    16801 tttaaatgaa gaaattgaat ttgaatagtg gatattttat ccttatttta gatcttagga
    16861 acacaagagg gcaaagatat gaatattact tatatagttg gaaatggttt ggatttgcaa
    16921 tatggtttga aaacaagata tagggatttc tacgaattcc aaaataaggt ttatataagt
    16981 aggacagaga acgaggaaaa atattcaaat ttcatttatg agtctctatt ttctgataaa
    17041 gtaaatgatt atgaaaattg gtcagatttt gaattgtcaa ttggtaaatt gacaaaagat
    17101 aacgacctca tctcctcaag tatagaaata aaggagaaat ttatagatga ttttagtgaa
    17161 gtagttgatg atttaagaga atatctacgc atacaacaag aaaaaaatct tgagaaaggt
    17221 aatgcaattg actttataag cactctagat gatatgagga cctctctccc tgtaattaat
    17281 caacctgcta tcgataaaaa atacaatgag aatccacatc aggacgacat tgtaaatata
    17341 gtaacactta attatacaca tgtaatcgat aaattatata atgggtcagc aaaatcattc
    17401 aggaatcaat tacgagctaa tctttataat ttttatattg agccaccaat tcatgcacat
    17461 gggacggtgg atgtctgcac ggttttaggg gttagtgatg aaatacaaat ttcaaatagt
    17521 ttagaagaac aaaaggaatc cctaataaaa agtttagttt taaaaaacta tagagaaaat
    17581 atggatgtaa agaatagtga tattataaaa aattctgaca tcattattct ctatggggtt
    17641 tctttgggag aaactgatag gtatatctgg agtcagattg ctgaacgatc aatcagcggt
    17701 tctgttcctg tcataattta ccactatgta cctcattttg atccggggaa tcccattaga
    17761 gcaaaacgcc tatatagaaa tgtagaagat aaattcatac agaatagtgg tatagactta
    17821 gagttagaga aaaaattaag agacaacctt attgtcgtta ttggtaagac tatttttgat
    17881 ctaatagaga ggtaatttta aaaaacaaaa tggaaacatg gcaagagtta aaagttacag
    17941 tgaagcgtga gggagaggag ttggtttcca atctcttgat tgagctggga gcgcaaggtg
    18001 ttgcgattga agacagtatg gactatgtgg gaaatgttga ccgctttggc gagattttcc
    18061 cagaggtgga gcagcaagaa gaaatcgtag tgacagccta ctaccctgac acggtggatg
    18121 tgacagtggt tgaggcggac ttgcaggctc gcttagcaga attgacggat tttatggatt
    18181 tgggagagtt aaaaataggt acgactgtct tggctgagga agactgggca gataactgga
    18241 agaaatacta tgagccagct cgtatcactc atgatttgac catcgttccc tcttggacag
    18301 actatgaggc gactgcgggg gaaatgatta tcaagctgga tcctggcatg gcttttggta
    18361 ctggaaccca cccaactacc aagatgagcc tttttgcctt ggaacaggtt cttcgtggtg
    18421 gcgaaacggt gctagatgtg gggactggtt caggggttct ctctattgcc agctcgcttc
    18481 tgggggctaa agaaattttc gcctatgacc tagatgatgt agcagttcgt gttgctcagg
    18541 aaaatattga acttaaccct ggaatggaaa atatccacgt tgctgctgga gacttgctta
    18601 agggtgttga gattgaggca gatgtgattg tagctaatat cttggcggat attctcattc
    18661 atctgacaga cgatgcctat cgtttggtca aggatgaagg ctacctgatc atgagtggca
    18721 ttatcaagga caagtgggac atggtgcgcg agtcggctga gtcagctgga tttttccttg
    18781 aaacccacat ggttcaaggg gaatggaatg cctgtgtctt taagaaaacc aaggatattt
    18841 ctggtgtgat tggaggctag catgcagcag tattttgtaa aaggcagtgc tatctctcct
    18901 gtcactatcg aggacaagga aaccagtaag catatgtttc aggttatgcg cttgaaagaa
    18961 gaggatgagg ttaccttagt ctttgatgat ggcatcaagc gcttggcgcg cgtgctggat
    19021 atggaaaatc gtcagtttga gttggtccaa gaattaaatg acaatgtgga actaccagtt
    19081 caagtgacca tcgcatctgg atttcccaag ggagacaagc tggagttcat cgctcaaaaa
    19141 gtaaccgaac tgggtgctag ccaaatctgg gcctttcctg cagactggtc agttgccaag
    19201 tgggatggca agaaattggg taaaaaagtt gaaaaactag aaaaaattgc ccttggagca
    19261 gccgagcaaa gcaagcgtaa tattgtacca agtattaaac ttttcgagaa aaaagcagat
    19321 tttctaactc agctggacca gtttgactct atcatagtag cctatgaaga atcagctaaa
    19381 gaaggagaag ccgctgcgct tctgcaagca gtcactggtc ttgaaacagg agccaaactg
    19441 ctctttatct ttggtccaga aggcggtctc tcacctgcag aaatcgaaag ttttgaagct
    19501 aagggagccg ttttggtagg cctaggtcct cgtattttgc gagcagaaac agcaccgctt
    19561 tacgccttat cagcccttag tgttttagta gaattagaga aataagagga agaaaatgga
    19621 acaaaaacac cgttcagaat ttccagagaa ggaactttgg gatttaacag ctctatacca
    19681 agaccgtgag gatttcttgc gtgcaatcga gaaagctcgc gaagacatca accagtttag
    19741 ccgtgattac aagggcaatc ttcacacttt tgaggatttc gagaaggcct ttgcggaatt
    19801 ggaacagatc tacattcaga tgagccatat tggcaactat gcttttatgc ctcagacgac
    19861 ggactatagc aatgacgaat ttgcaaatat tgctcaagct gggatggaat ttgaaacaga
    19921 tgccagcgta gccttgacct tctttgacga tgccttggtg gtagcagacg aggaagtctt
    19981 ggaccgtttg ggtgaattgc ctcacttgac ggcagctatt cgtcaggcca aaatcaaaaa
    20041 agcccactat ctaggggctg atgtggagaa ggccttgacc aatctcggtg aagttttcta
    20101 tagtccgcag gacatttata ctaagatgcg agctggggat tttgaaatgg ctgactttga
    20161 agcccatggc aagacctata aaaacagctt tgtcacctat gagaatttct accaaaatca
    20221 cgaggatgct gaggttcgtg agaaatcctt ccgttccttc tcagagggac ttcgtaagca
    20281 ccaaaatacg gctgcagcag cctatctggc tcaggtcaag tctgaaaaac tcttggctga
    20341 tatgaaggga tacgactctg tctttgatta tcttctagct gaacaagaag tggaccgtgt
    20401 catgtttgac cgccagattg acctcatcat gaaggacttt gcaccaatcg ctcagagata
    20461 cctcaagcat gttgccaagg taaatggtct tgaaaagatg acctttgcag actggaaatt
    20521 ggacttggac agcgccctca atcctgaagt gactattgac gatgcctatg atttggtcat
    20581 gaagtcggta gaacctttgg ggcaagaata ttgtcaggaa gttgctcgtt accaagaaga
    20641 gcgctgggtg gactttgctg ctaacagtgg caaggattcc ggtggttatg cggcggaccc
    20701 atatcgcgta cacccttatg tactcatgag ctggacaggc cgtttgagcg atgtctatac
    20761 cttgattcat gaaatcgggc attctggtca attcatcttt tcagacaatc accaaagcta
    20821 tttcaacgcc cacatgtcga cctattatgt tgaagcaccg tcgaccttca atgaattgct
    20881 actcagtgat tacttagaga accagtctaa tgacccacgt caaaaacgct tcgctctggc
    20941 tcatcgcttg acagacacct acttccataa tttcatcacc cacctcttgg aagccgcctt
    21001 ccagcgtaag gtgtatacat tgattgaaga aggagaaacc ttcggagcaa gcaaactcaa
    21061 cagcattatg aaggaagttt tgacagattt ttggggcgat gccattgaaa tcgacgacga
    21121 tgcagctttg acttggatgc gccaagctca ctactatatg ggcttgtata gttacactta
    21181 ctctgctggt cttgtcatct cgacagctgg ttaccttcat cttaaaaact cagaaactgg
    21241 agctgaagac tggctcaatc tcctcaaatc aggtggtagc aagacaccac ttgagtcagc
    21301 catgattatc ggtgctgata tttcaacaga caaaccactc cgtgatacca tccaattctt
    21361 gtctgacaca gttgaccaga ttatcgccta cagtgctgag ttgggggagt aaggggaata
    21421 gaaaaatttt ctagaatgat gtttatgggc ttgttaagcg tcattctatt tgtcttagtt
    21481 gtagctattt tcaaaaatgt cgttgaaggt cgtgatgtta aatttgaact tactgtagaa
    21541 ctggtattga tagttattta cgtcatttta tatcagattg tatttaattg agaattcaat
    21601 attgagtcat ttaagactgc ctttttgaac agttgctaga aatgtagagg tattgaccat
    21661 gtatcaagat ttactaagaa aaatagcaga agaaaaacca aattataacc aggaagaaat
    21721 ccagtggttg tttgatcatt tgggaaatcc ttctccagaa attcgtgatg acctttcaaa
    21781 tcaaggcttg cactatcttt caaaagaaaa ggatacaaca ggtttctcaa gtcagtatgg
    21841 ttgggttcac gcttttgcac atggagccga tttactgaca gaggtggttt gtcatccaga
    21901 ctttcctaaa aacagagttc atgaagtatt tgatatactt ggccaactat ttaaaagaat
    21961 gtcgattcgc tttacagatg atgaggattg gcgtttagca agagtgatct atgaacctat
    22021 tttacaaggg aagttggagc aagaacaagt agcttcttgg ataaaaactg ttgattttcc
    22081 gatagaagaa agggaggatt tttacaaatt ttccaacttt agatcctgtc tggtggaagt
    22141 ctatgtccaa cttgaccaga gaaatagttt acaagatgag ttgaaagaag ctatccagtc
    22201 ttttcaatac tagagattag ctaatagttc tatgattttc aaaaaatttc caatcaattt
    22261 tcttgaaacc ctttcctact tttgatagac tagtatctag tttttgaaaa aaggagaaag
    22321 aaaatgaaaa aatttgttgc tgagttaatc ggtacgttca tgcttgtgtt cgttgggaca
    22381 ggagctgttg tttttggaaa tggtcttgat ggccttggtc accttggaat cgcctttgcc
    22441 tttggtttgg caatcgtggt ggcagcctac tcaatcggaa ctgtttcagg tgctcacttg
    22501 aacccggctg tttcgattgc tatgtttgta aacaaacgtt tgtcatcttc agaacttgta
    22561 aactacatcc ttggtcaggt tgttggagct ttcatcgctt ctggcgctgt cttcttcctc
    22621 ttggctaact caggtatgtc aactgctagt cttggtgaaa atgccttggc aaacggtgtc
    22681 actgtctttg gtggtttctt gtttgaagtc atcgcaactt tcttgtttgt attggttatc
    22741 atgactgtga cttcagaaag caagggcaat ggcgcgattg ctggtttggt aatcggtttg
    22801 tcattgatgg cgatgattct tgtcggattg aagattactg gactttcagt aaacccagct
    22861 cgtagcttgg caccagctgt cttggtaggc ggcgcagccc ttcaacaagt ttggattttc
    22921 atccttgcac caatcgctgg tggagttctt gcagcccttg ttgcaaaaaa tttccttgga
    22981 acagaagaat aattgaaact caaaaagcct tgctcctcat cttgaggaac agggcttttt
    23041 cgtatgatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc cgtaggtatg
    23101 gttactgact tcgtcagttc tatcc
//
LOCUS       DAVKEV010000035        22523 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVKEV010000035 DAVKEV010000000
VERSION     DAVKEV010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22523
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.035"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            100..753
                     /locus_tag="VWZ68_001511"
     CDS             100..753
                     /locus_tag="VWZ68_001511"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEU9372519.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            763..1227
                     /locus_tag="VWZ68_001512"
     CDS             763..1227
                     /locus_tag="VWZ68_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU9372520.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1240..2508
                     /locus_tag="VWZ68_001513"
     CDS             1240..2508
                     /locus_tag="VWZ68_001513"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEU9372521.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIASEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2522..2782
                     /locus_tag="VWZ68_001514"
     CDS             2522..2782
                     /locus_tag="VWZ68_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372522.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2793..4154
                     /gene="pdrM"
                     /locus_tag="VWZ68_001515"
     CDS             2793..4154
                     /gene="pdrM"
                     /locus_tag="VWZ68_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEU9372523.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4308..5276
                     /locus_tag="VWZ68_001516"
     CDS             4308..5276
                     /locus_tag="VWZ68_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEU9372524.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGSVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5292..6284
                     /locus_tag="VWZ68_001517"
     CDS             5292..6284
                     /locus_tag="VWZ68_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEU9372525.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEEISVEIVDPRTLVPLDKDIIINSVKKTGKVILVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCSGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKD"
     gene            6502..7545
                     /locus_tag="VWZ68_001518"
     CDS             6502..7545
                     /locus_tag="VWZ68_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEU9372526.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7609..9294
                     /gene="lpdA"
                     /locus_tag="VWZ68_001519"
     CDS             7609..9294
                     /gene="lpdA"
                     /locus_tag="VWZ68_001519"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEU9372527.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHSAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVAVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9358..10347
                     /locus_tag="VWZ68_001520"
     CDS             9358..10347
                     /locus_tag="VWZ68_001520"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEU9372528.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEAVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10420..11490)
                     /gene="xerS"
                     /locus_tag="VWZ68_001521"
     CDS             complement(10420..11490)
                     /gene="xerS"
                     /locus_tag="VWZ68_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEU9372529.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(11984..13534)
                     /locus_tag="VWZ68_001522"
     CDS             complement(11984..13534)
                     /locus_tag="VWZ68_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEU9372530.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(13550..14329)
                     /locus_tag="VWZ68_001523"
     CDS             complement(13550..14329)
                     /locus_tag="VWZ68_001523"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEU9372531.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKEN"
     gene            complement(14316..15167)
                     /gene="ylqF"
                     /locus_tag="VWZ68_001524"
     CDS             complement(14316..15167)
                     /gene="ylqF"
                     /locus_tag="VWZ68_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEU9372532.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWCQYFESQEIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(15413..20662)
                     /locus_tag="VWZ68_001525"
     CDS             complement(15413..20662)
                     /locus_tag="VWZ68_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU9372533.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVIGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVQPALPEAVVTDKGEPEVQPTLPEAVVTDKG
                     EPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVGTTGVDENGNLIEPPVNDIPEYTEP
                     ISTVSEVASEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVKEVGEDGERQIVT
                     SYEELHGKKISEPVETVTILKEMKPKILVKGTKENPKEKTVPVLTLTKVTEDAMNRSA
                     NLNYELDNKDNAEISSIIAEIKDGDTVVKKVDLSKEKLTDAVQNLDLFKDYKIATTMI
                     YDRGQGSETSKLDEKTLRLELKKVEIKNISSTNLVKVNDDGTEIPSDFMSEKPSDEDV
                     KKMYLKITSRDNKVTRLAVDKIELVTEKEKELYKITASAQDLIQHVDPSKTRNEYIHY
                     IEKPVPKVNNVYYNFNELVRDMQEHPNDEFKLGADLNATNVSAFGKSYVTKDFKGKLL
                     SDGDNHYTIHNLSRPLFGNVIGGTIKNINLGNVDINMPWANQVAAVANIIKGGTTIEN
                     VKVKGNIVGKDWVSGFIDKIDNQGTLRNVAFIGNVTSVGDGGQFLTGIVGENWKGLVE
                     RAYVNANLIGKKAKAAGIAYWTQNEGNNNTVRQEGAIKKSIAKGTIQVTEAIESGGVV
                     GSMKHHGSVEDSVSMMKVPNGEIFYGSSDIDYDDGYWTGDNVRRNYVVIGVSDGHSSY
                     QRSKDKNRIRPISEEEAKSKIEATGITADKYEINEPVVNRLNRLTRREDEYKSTQDYK
                     VDRDLAYRNIEKLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDI
                     DHVMIHYADKTKEIKAVHQKESKVAQVREYSIDGLDDIVYTPNMVDKNRDQLIKDIKD
                     RLATVELISPEVRALMDKRDTSRDPNANSDERKNGYIRDLYFEESFSETKANLDKLVK
                     SLIENADHQLNSDEAAMKALVKKVDENKAKIVMALTYLNRYYDIKYGDMTIKNLMMFK
                     PDFYGKSVDLLDFLIRIGSSERNIKGDRTLDAYRDMIGGTIGKSELHGFLDYNMRLFT
                     NDTDLNDWFIHAAKNVYIVEPKTTNPDFVNKRHRAFDGLNNGVHNRMILPLLTLKNAH
                     MFLISTYNTMAYSSFEKYGKYTEAEREAFKDKIKEVAHAQQTYLDFWSRLALPSVRDQ
                     LLKSQNRVPTPVWDNQNYHNVEGVNRMGYDKNNKPIAPIRELYGPTWRYHTTNWYMGA
                     MASIFQDPNNNDQVYFMGTNMISPFGISAFTHETTHVNDRMLYFGGHRHRQGTDVEAY
                     AQGMLQTPDKSGNGEYGALGLNMAYHRENDGDQWYNYDPDKLKTREDIDRYMRNYNDA
                     LMMLDHLEADAVIPKLHGNISRWFKKMDRQYRKNGELHQFDKVRELTEDEKKKIVINN
                     IDDLVNNNLMTKHGAPSDRTYNPEDFDSAYVNINIMTGIYGGNTSQGAPGAASFKHNT
                     FRMWGYFGYENGFISYASSKYQGEADKTNKKLLGDDFIIKKVSKDKFNNLEEWKKQYF
                     KDVKSKAEKGFTAIEIDGRQITNYAQLKTLFAEAVQKDIDGMSDPKIKDHFKNTVDLK
                     SKVFKALLKNTDGFFNKLFKEDI"
     gene            complement(20706..>22523)
                     /locus_tag="VWZ68_001526"
     CDS             complement(20706..>22523)
                     /locus_tag="VWZ68_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HEU9372534.1"
                     /translation="LGKSGFNNLLAKNNVITYNVLLAKNYGTESLFKALEGYRKVFLP
                     TISNNEWFKKQTKAYIVEEKSTIEEGREKQGKEGTKYSIGVYDRLTNPSWKYQSMVLP
                     LLTLPEEKTVFMIANISTIGFGAYDRYRSSEYPKGEKLNKFVEDNAKEAAKRFRDHYD
                     YWYKILDNDNKEKLYRSILVYDAFKFGTDKDKDKVTHQATFETDHPAIKYFFGPAGNN
                     VVHNGHGAYATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRSGLGPEF
                     YAKGLLQAPDHPYDPTITINSVLKYEDSENSTRLQVADPTQRFNSAEDLHNYMHNMFD
                     VIYMLEYLEGKAVANLETNQKYELLRKIENKFDLDQDGNNVYATNVVRRLTMDEVNKL
                     NSFDSLIENDIITSRGYKDQEYKRNGYYTIDLFSPIYSALSGEKGTPGDLMGRRIAFE
                     LLAAKGYKEGMVPYISNQYEKDAKAAGSKINSYGKEVGLVTDELVLEKVFNGQYKTWT
                     QFKKDMYKEREKQFSKLNRVNFINPNNPLSRQRNVSVTDIGVLERMIVEAVRDDAQDD
                     VAKFYPETNSRVLKLKKAIYKAYLDQTNDFRSSIFENKK"
BASE COUNT         6616 a         4383 c         4350 g         7174 t
ORIGIN      
        1 tatatagtcg atttattaaa tctttagata aactgtaaaa agtggtttcc atagccactt
       61 tttgctataa tagaggcagt aaaaatgaag gagtcggcta tggaacactc gtcttggcat
      121 gctttgatta aggcgcaatt acctgagggt tatttcggga aaatcaatca gtttatggag
      181 caggtctatt ctcaggggat tatttatcca cccaaggaaa aggtttttca ggctctcttg
      241 acaacactgc ttgaagaagt taaggtggta attctagggc aagaccccta tcacggacca
      301 ggtcaagcgc agggcttgag tttttctgta cctgactcta tcccagctcc accatccttg
      361 caaaatatct tgaaagaatt gtcagatgat atcggagtta agaaatctca tgatttgaca
      421 gcttgggctg agcaaggagt cttgcttctt aatgcttgtt tgactgttcc tgctggacag
      481 gccaatggtc atgctggtca aatctgggag ccttttactg atgctgtgat tcaggtggtc
      541 aatcatctag atagaccagt cgtttttgta ctctggggag cttatgcacg taagaagaag
      601 gcattagtta ccaatcctca tcacttgatt atcgaatcag cccatccaag tcctttgtcg
      661 gtttatagag gattttgggg ttccaagccc ttttccaagg ccaatgcatt cttaaaagag
      721 acaggacaag agccaatcga ttggcttaga taaggagaaa atatgcctca gttagcgacg
      781 atttgctaca ttgataatgg gaaagaactg ctcatgctcc atcgtaataa gaaacccaat
      841 gatgtccatg aagggaaatg gattggtgtg ggtggtaagc tagagagagg agagacgccc
      901 caggaatgcg cggcgcgtga aatccttgaa gaaacagggc tcaaagccaa gccagttcta
      961 aaaggtgtca tcacttttcc tgaatttaca ccagatttag actggtacac ctatgttttt
     1021 aaggtgacgg agtttgaggg cgacttgatt gactgcaatg aggggacgct agaatgggtt
     1081 ccctatgatg aggttttgag caagccgact tgggaaggtg accacacctt tgttgagtgg
     1141 cttttagagg ataaaccctt cttttcagcc aagtttgttt atgatgggga taaattgttg
     1201 gatacccaag ttgatttcta tgaataaagg agaaagcaga tgctactaat caaaaatggt
     1261 cgtgtaatgg atcccaagtc tggtttggat caagtttgtg atgtcttagt tcaagatggg
     1321 aaaattatca aaattgcgtc tgagatcacg gaagaaggag cagaaacgat tgatgctact
     1381 ggtcttgtgg ttgctcctgg cttggtcgat attcatgttc atttccgtga acctggtcaa
     1441 acacataaag aagacattca tactggtgcc ctagcagccg ctgcaggtgg ttttactact
     1501 gtcgtcatga tggctaatac cagtccaacc atttcagacg tggagacttt gcaagcagtt
     1561 ctccagtcag ctgccaaaga gaagattaat gtcaagacag ttgcgaccat tactaaaaac
     1621 tttaatggta aaaacttgac tgactttaag gcactcttag aagctggtgc ggttggtttc
     1681 tctgatgacg gtattccgct tgagagcagt aagattgtca aggaagccat ggaggaagcc
     1741 aaaaaactca atacctttat cagccttcat gaggaagatc caggtttgaa cggtgttctt
     1801 ggctttaatg aaaatattgc tagagaacat ttccatatct gcggtgctac tggggtggct
     1861 gagtacgcta tgatggcgcg tgatgtcatg attgcctatg caactaaagc ccatgttcac
     1921 atccagcatt tgtctaagga agaaagtgtt aaagtagtgg agtttgctca ggggttaggt
     1981 gcagaagtca cagcagaagt agcgccacag catttctcta agacagaagc acttctttta
     2041 acacaaggta gcaatgctaa gatgaatcca ccgcttcgtt tggaatcaga ccgtcgtgcc
     2101 gttatcgaag gtctcaaatc aggtgtcatc acagttattg cgactgacca cgcgcctcat
     2161 catgtagatg aaaaaaatgt tgaggatatt accaaagcgc catctggtat gactggctta
     2221 gaaacatccc tgtctctcag cttgacctat ttagtagaag ctggtgagtt gagcttgatg
     2281 gaattacttg aaaaaatgac atacaaccca gccaagcttt acaactttga agcaggttac
     2341 ttggctgaga atggtccagc agatatcact atttttgatg ccaaggctga ccgctttgtg
     2401 gactcccatt ttgcttccaa agcagctaat tcaccattca tcggtgaaac cttaaaaggg
     2461 caggttaaat ataccatctg taagggacaa atcgtctatc aagcttgata ggagttagaa
     2521 tatgaattat tttcgaaaac gtagggagag acaagcgaaa tctaatagtg gaatttactg
     2581 tcccgcagct aatcgttcca aaattcaata tgaaactaaa gaaaaagctg accatgcggt
     2641 tcaatatgat aacggaggtt tagttagaag ctattattgt cgtacatgtg cgtgttggca
     2701 tactacttca aaatctaata aacctccgct aagtttgaaa aactatggtc tgaaactctt
     2761 tggtttagat aaatcagaat agaaagagaa gtatgtataa gacaaagtgt ttacgagaga
     2821 agttagtatt atttttaaaa attttcttcc caatcctgat ctaccaattt gccaattatt
     2881 ctgcctcttt tgttgatact gcaatgacag gtcaatacaa cactatggac ttggctggtg
     2941 tatctatggc aaccagtatc tggaatcctt tctttacatt tctaacaggg attgtgtcag
     3001 ccttggtgcc tatcattggt caccatcttg gtcgaggcaa aaaggaagaa gttgcgtctg
     3061 atttttacca atttatttat ttggccttgg gcctatctgt ggtcttgctg gggatggtac
     3121 ttttcttggc accaataatc ttgaatcata ttgggttaga agcagcagta gcggcagtag
     3181 cggttcgcta tctttggttt ttatctatcg ggattatccc cttgttgctc tttagcgtca
     3241 ttcgttcctt gctggattcg ctgggcttga ccaaactgtc catgtacctc atgcttttgt
     3301 tactccctct caatagcgga tttaactatc tcttgattta cggtgccttt ggtgttccag
     3361 aactgggagg ggctggtgct ggtttaggaa catccttggc ctactgggtc ttgcttggga
     3421 tttctgttct ggttttattt aaacaggaga agctcaaagc cttacacctt gagaaacgaa
     3481 ttccacttaa tatggataac attaaggaag gagttcgttt aggtctgcct attgggggaa
     3541 ctgtcttcgc ggaagtggct atcttttcag tggttggctt gattatggct aagttttcgt
     3601 ccttgattat agctagtcac cagtcagcta tgaacttttc aagtcttatg tacgcctttc
     3661 ctatgagtat ctcatcggct atggctattg tcgtttccta tgaagtggga gccaagcgat
     3721 ttgatgatgc gaaaacctat attggtctag gaagatggac tgctctcatt tttgcggcct
     3781 tcaccctaac cttcctttac atttttaggg gaaatgtggc cagtctttat ggtaacgacc
     3841 caaaatttat cgatttgaca gcgcgttttt taacttatag tcttttcttc cagttagcag
     3901 atacctttgc ggcaccgctt cagggaattt tgcgggggta taaggataca gttattcctt
     3961 tttaccttgg tttgcttggt tattggggcg tagcaatccc tgtggctacg ctatttgatt
     4021 ccctaacaga ttttggagct tattcttact ggatcggctt gattattagt ttgattgtga
     4081 gtggggcgct ctaccgttgg cgtttaactg tgattatgaa gagatttgaa tctttagcaa
     4141 aatccaaacg ctaaaaagtt tgtgaaaaaa tattcttgac aagaaaatcc cttgttttca
     4201 cggggttttc ttttttattt tgtgaaattt cttttagaaa aactttgaca gtatttgcca
     4261 aaagcggtaa aatagtaagg taagaagaaa gttagaaagg caagaagatg tcaactttag
     4321 ataaaaatct tttgctagaa atgttccgta agatggaaga aatccgtcgc atggacttaa
     4381 aaattgcaca attagtaaag aaagggaaag tgccaggaat gacgcacttt tctgttggtg
     4441 aagaggcagc taacgtgggg gctatgttag ctctcaatcc agatgatctg attacctcaa
     4501 accaccgtgg acacgggcaa gctattgcta aagggattga cctcaacgga atgatggctg
     4561 aaatccttgg taaatacact ggaacctgta aagggaaagg tggatctatg catatcgctg
     4621 accttgatgc tgggaacctt ggtgccaatg gtatcgtagg tggtggtatg gggatcgctg
     4681 tcggtgcagc cctcagtcag caaatgcaaa ataccggtaa aatcgttgtc tgcttctttg
     4741 gagatggtgc gaccaatgaa ggtgttttcc acgaagcagt gaacatggct tctatctgga
     4801 acctgccagt cattttctat tgcattaaca acggttacgg tatctctgcg gatatcaaga
     4861 aaatgaccaa tatagaacat atccatcaac gtagcgccgc ttatggaatt cctggaatgt
     4921 tcatcgaaga tggtaacaat gtcatcgatg tctatgaagg atttcagaaa gctgtggacc
     4981 atgttcgcag tggcaatggt tcagtcttga ttgaaagtgt aacttatcgc tggctcggtc
     5041 actcatcatc tgaccctggt aaatatcgta cgcgtgaaga agtggaattg tggaaacaaa
     5101 aagatccaat cgaaaacctc cgcaattacc ttattgaaaa taacattgca agtgccgaag
     5161 aattggaaga aatccaagcg caagtaaagg aagcagtaga agcttctgtt aaatttgcag
     5221 aggaaagccc attcccaccg cttgaatcag cctttgaaga tatttacgca gactaaggag
     5281 aaagagataa aatggaaaca aaaacaatgt ccttccgtga caccattatc cttgctatgt
     5341 ctgaggaaat gcgtcgcgat gaaaatgtgt tcttgatggg agaagatgtc ggtgtcttcg
     5401 gaggagactt cggtacttct gttggaatgc ttgaagaatt tggtccagaa cgtgtccgtg
     5461 actgtccgat ttctgaagct gccatctctg gagcagcagc aggagcagcc atgacaggac
     5521 ttcgtccaat cgtcgatatg accttcatgg acttctctgt tattgccatg gacaatatcg
     5581 tcaaccaagc tgctaaaaca cgttacatgt ttggtggtaa aggtcaggtt ccaatgactg
     5641 ttcgttgtgc agctggtaac ggagttggct ctgccgccca gcactcacaa tctctagagt
     5701 cttggtttac tcacattcca ggacttaagg ttgtggcacc tggaacacct gcggacatga
     5761 aaggcctgct taagtcttct atccgtgata acaacccagt tattatactt gagtacaagt
     5821 cagaatttaa ccaaaaaggg gaagtgccag ttgatccaga ctacacaatt ccacttgggg
     5881 ttggtgaaat caaacgccaa ggaacggatg taacagttgt tacttatgga aaaatgcttc
     5941 gccgtgtggt tcaagctgct gaagaattag cagaagaaga aatttcagtt gaaattgttg
     6001 acccacgtac ccttgttccg cttgataagg atatcatcat aaactcagtg aagaagactg
     6061 gtaaggttat tctggtcaac gatgcccaca aaacaagtgg ctatatcggt gaaatttcag
     6121 ctattatttc agaatcagaa gcatttgact atctagatgc accaatacgc cgttgttcag
     6181 gagaagatgt gccgatgcct tatgcacaaa acctagaaaa tgcaatgatt ccaacagttg
     6241 aaagtatcaa agatgcaatc cgaaaaactt ataacaaaga ctagagttac ataatataag
     6301 ttatgtaact aaaataaagc tgacgagaaa ctttgtatct tttaggtgca gagctcttcg
     6361 tcattaatat cttatattcg agcacgggct aaaagctcgg aaaaaagata aatctccttg
     6421 gcttcatcga agccatcgtc gatttcctat ttttcagtcg cttttgacgc cctttgtatc
     6481 ataaatagaa ttggagaggt catggctgat gacaagctaa gagcgactcc tgcagctaga
     6541 aagttagcgg atgatttagg gataaacctc tacgacgttt ctggctcagg tgcaaacggt
     6601 cgtgtccaca aagaagacgt ggaaacttat aaagacacaa acgtggttcg catttcgcca
     6661 cttgcaaaac gaattgccct cgaacataac attgcttggc aggaaatcca aggaaccggt
     6721 catcgtggta aaatcatgaa gaaggatgtt ttggccctgc ttcctgaaaa tatcgaaaac
     6781 gatagcatca aatctcctgc tcagattgaa aaagtggaag aagtccctga taacgtaaca
     6841 ccatatggtg aaatcgagcg tattccaatg acaccaatgc gtaaggttat tgcccaacgc
     6901 atggttgaat cttacttgac tgcgccaacc ttcaccctca actatgaagt tgatatgact
     6961 gaaatgttgg ctcttcgtaa gaaggttctt gagccaatca tggaagcaac tgggaagaag
     7021 actactgtaa cagaccttct ttcgcttgca gttgttaaga ctcttatgaa acacccatac
     7081 atcaacgctt cattgacaga agatggcaag actattatca ctcacaacta tgtcaatctt
     7141 gccatggcag ttgggatgga taatggattg atgacacctg ttgtttacaa tgctgagaag
     7201 atgagtcttt cagaactggt ggtagccttt aaggatgtta ttggccgtac cttggatggt
     7261 aaattggctc caagtgagtt acaaaattca acattcacaa tcagtaattt gggaatgttt
     7321 ggtgttcagt cctttggtcc gattattaac caacccaact cagctatcct tggtgtcagt
     7381 tcgacaatcg agaagccagt tgtcgtcaat ggtgaaattg tgattcgccc aatcatgagt
     7441 ttaggattaa ccattgacca ccgtgtcgta gatggtatgg ctggtgctaa gtttatgaag
     7501 gacttgaaag agttgattga aacgccaatc tcaatgttaa tttaagagca agagtattca
     7561 tttttaagat atagataaag gaaggaagac atggccttag aaataattat gccaaaagcc
     7621 ggcgtggata tgacagaagg acaaatcgtc caatggaata aaaaagtcgg agaatttgta
     7681 aaagaaggag aaatcctttt ggaaatcatg actgataaag tcagcatgga attggaagcc
     7741 gaagaagatg ggtacttgat tgccattctc aaaggagatg gtgaaactgt ccctgtaacg
     7801 gaagttatcg gttaccttgg tgaagaaagg gaaaacatcc caacagctgg agcagcatcg
     7861 ccagaagcta gccctgtacc tgtagcaagt acctcaaacg atgatggtaa gagcgatgat
     7921 gcttttgata tcgttgtgat tggtggaggt cctgctggtt atgttgcagc cattaaagct
     7981 gcccaactcg gcggtaaggt tgcccttgtt gagaaatctg aacttggtgg aacctgctta
     8041 aaccgtggat gtattccaac caagacctac cttcatagcg ctgaaattat tgaaaatatc
     8101 ggtcatgctg caaatcgtgg tatcgtgatt gaaaatccta acttcactgt tgatatggaa
     8161 aaacttttag aaactaaatc taaagttgtt aatactcttg ttggtggtgt tgcaggactt
     8221 cttcgtagct acggagttgc tgttcataaa ggaattggta caatcactaa agacaagaac
     8281 gtcttggtaa atggttctga attgcttgaa accaagaaaa tcattcttgc tggtggttca
     8341 aaagtcagca agatcaacgt ccctggtatg gaatctccac ttgtcatgac tagtgatgac
     8401 attcttgaaa tgaacgaagt gccagaaagc cttgttatca tcggtggtgg agttgtcggt
     8461 atcgaactcg gtcaggcctt catgacattt ggttcaaaag tgactgttat cgaaatgatg
     8521 gaccgtatag ttccagctat ggatgtggaa gtttctaaga accttcgctt gatccttgag
     8581 cgtaaaggaa tgaccatctt gactggtact aaactgcaag aaatcattga ggaaaatggt
     8641 caacttcgta tcaaggttga aggaaaagac gatatcatcg caagcaaagc tcttctttca
     8701 attggtcgta tgccagacct tgaaggtatt ggagaggttg agtttgaatt ggatcgtggt
     8761 tgtatcaagg tcaacgaata catggaaact tcagttccag gcatttatgc accaggtgac
     8821 atcaacggta ctaagatgtt ggctcacgca gctttccgca tgggtgaagt ttccgctgaa
     8881 aatgccctta aaggaaatca tgcagttgcc aaattgaatt tgactcctgc agccatctac
     8941 actcttcctg aagtagcagc agtaggtttg acagaagaac aagcccgtga gaaatacgat
     9001 gttgccatcg gtaagtttaa ctttgctgct aacggtcgtg ctattgcatc tgacgcagct
     9061 caaggtttcg taaaagttat cgctgataag aaatacggag aaatccttgg tgtacacatt
     9121 attggtcctg cagccgcaga attaataaac gaagcatcaa gcatcatcga aatggaaatc
     9181 actgttgagg aaatgctgaa gaccatccac gggcacccaa cttactctga agtgatgtac
     9241 gaagcgtttg cagatgttct aggaatggcc atccattcac ctaagaaaaa ataaaacgaa
     9301 gatagattag actggaaggt tatttccagt ttctatcata taaagtaaag ggatatcatg
     9361 aaatacatta tcaatcattc aaatgacact gcttttaata ttgccttgga agaatacgcc
     9421 tttaaacacc ttttggatga ggatcaaatc ttcctacttt ggattaacaa gccatctatc
     9481 attgttggtc gtcaccagaa cactattgaa gaaatcaacc gtgattatgt tcgcgaaaat
     9541 ggtattgagg tagttcgccg tattagtggt ggtggagctg tttaccacga tttaaataac
     9601 ctcaactaca cgatcatctc caaagaagat gaaaataagg catttgactt caagagcttc
     9661 tcaactccgg ttatcaatac cttggctcaa ctcggggtta aagctgagtt cacaggtcgt
     9721 aatgaccttg agattgatgg taagaagttc tgtggcaatg cccaagccta tatcaacggc
     9781 cgtatcatgc accacggttg cttgctcttt gacgttgatt tgtcagtcct cgcaaatgcc
     9841 cttaaggttt caaaagataa atttgaatca aaaggtgtga aatccgtccg tgcccgtgta
     9901 accaatatta tcaatgaatt accaaaaaaa atcacagtcg aaaaattccg tgatttactc
     9961 ttggaataca tgaaaaaaga gtacccagag atgactgaat acgtcttttc agaagaagaa
    10021 ttggccgaaa tcaatcgcat caaggatact aagtttggaa cttgggactg gaactatggt
    10081 aaatcacctg aatttaacgt ccgtcgtgga accaaattca ctagtggtaa ggttgaagtc
    10141 tttgctaacg ttactgaatc aaaaatccaa gacatcaaga tttatggtga cttctttggt
    10201 attgaagacg ttgctgcagt agaagctgtc cttcgtgggg tgaaatacga acgcgaagat
    10261 gttcttaagg cgctaaaaac cattgatatc acacgctact tcgctggtat tagccgtgaa
    10321 gaaatcgctg aagcggtagt tggataaatc aaaaagaagt tggccaacta accaacttct
    10381 ttttttgata tttatttaca taatttaaaa tacgtaaaat cataaactat ccagagcatt
    10441 cttttgttca tcactaacaa tatgggtata gaggtcagtg acttgtgtgc tagcatgtcc
    10501 tagttggtga ctgactaaaa cttgtgattt agtcgcatca tagagcctag ttgctagtgt
    10561 atggcgcagt ttatggggtg ttacacgcac tttaaaatcc tctgagtatt tagcaaccat
    10621 tttctcaacg ctagaagcat cgatacgatt aggaacacct ctgtagagag ttaaaaaaag
    10681 ggctgtatct gttttttccg ttttatagcg ttgattccga atggccagat aattctctaa
    10741 ataaggttta gcaaaagcag cgacattgac tgagtcacgt ttgccacctt ttcgagtaac
    10801 atcaataacc atcattttta gattgagatc tcttagatct agattaacag cttcagataa
    10861 gcgaacacca gatgccaaga gaagggcaat aatggctaaa tctcgttctt tatttttgtt
    10921 gaatgatgag agagctcgat ttgaaagctg ttgtgggtgc tcttgatcga tataagttag
    10981 aaaaccttct gtttcatcac ctagaaagag tttttgcttg atattttcag ctctggcagc
    11041 aagggtttct ttctttttct tggttgaaac ttttttcatt acattacgat agaaataagg
    11101 ttccccctga tcgttttcaa cctcctcggt tagatacttg taaagactag aaagtgctga
    11161 taaggttcga ttgatagttg tctgtgaaac accttgtttt gttgtattag cattcagcaa
    11221 gggacgttca cgtagataaa ggataaagga ttccatgtct ttcttagaca tattttccaa
    11281 aactgataaa ggaatatcgg atattttatc agcgtttgaa ataccagact ccaaaaccca
    11341 gctgaaaaat cggtcatatt ccttaaggta ttcgtacagg gttgtaaaac tgtagggcac
    11401 agccagttta gattggtagt attccagaac ataccagggc atgagttgtt ttagtttgtc
    11461 gattcgttcc agtaaaatct cacgtttcat gtattttctc cataattaag tatactagta
    11521 gtatagcata gacttgtaca tttttcaaga aaattatagt ttttcagaaa gatgttatag
    11581 gagtttttca aagtgataaa aagacttaga cctacaaaca aaacagaata aggaaaataa
    11641 taaaaatctc acccactaaa cttctgttaa tactacatag ctagaaattg gtttgattgt
    11701 cctgattgtt ttatcctatt tctatttcat ttcactatat aattgctatt gttttctttt
    11761 tcatgatttt aatcttactg tacagatttg atacagtaaa ctcctttcta gctttatact
    11821 ttatcatttc taacttaatt atagtcttat ttttaataaa gttcaattat ttatatgtaa
    11881 aattcctcat cagtaaaaaa taaccgatct catttctgag aatcggtttt ctaaataaat
    11941 caagccgatc atttacataa cataaattat gtaaatgatc gtactacaac aacaaatctt
    12001 tgacttttcc aatttcactt tttggaataa ccaggtgaat catatcaccc agatacattc
    12061 tggttgagcc gttaactgtt tggctcttgc cattatggac ttgagttgtg atgaggacgt
    12121 tgtgtggtaa gttgagttca tgaacttgtt tcccagcaat tttatcagaa actggtattt
    12181 cgataagtgt aacttctcct tcgctagata cttcttctgg aagcattttt tccagcatgg
    12241 cttcatagac tggcgtacct ttgagcaaat ccatgataat ataagaaaca agagtgacaa
    12301 gaccaagtgg catgaggttg cgaatatctc ctaccatctc agttacgagg atcatagcag
    12361 ttaagggagc ttttgatatg gctccaaaat agccactcat tcctagaatg acaaatatag
    12421 ggaattgctc ttgactgaca agtccaagat tgacacagat aacaccaact aaggcaccaa
    12481 gcaaagaacc aagagctaaa atggggagga aaattcctcc tggcagtcca cttccatagc
    12541 taatcatact ccaaataaag cggattaaaa agtaagctaa taaaacttgg aaactaaaat
    12601 tttgttcagt taaagaaagg acaagctgat ttccgccacc aatgatttga ggtaagaaga
    12661 ttccgactgg tatgataagg ataaaagcca agatgggata ataagcccta tccaaatgga
    12721 ttttttgacc aatcaagtca taaactcttc caacgtttaa tacagctttc tcatagagaa
    12781 aacctgaaaa tccaaggaaa attcccatga cgagatatat ccaatactga tctagggtca
    12841 tgggaggaat gttatctggc atatccaata ctggtgtcaa accgaacatg agtagagaca
    12901 caaagtttgc tacgatgctg gctgctagag ttgagaccca gaaaaagcgc gaaaaatggt
    12961 gatagacttc ttctacaaca aagagaagtg ctgcaatagg agcattaaag gctgcggcta
    13021 aacctgctgc agctccactg gcaatcaagg aacgttcctc tactggactg gatttgagcc
    13081 acttggcaat tcctttacca ccaactgctc caagttgaat gctgggtccc tctcgaccca
    13141 gcatgagtcc actggcaata gcaagaatac ctagcacata ttttttccaa agaatgcccc
    13201 accagttgag ggacatgagg cctttcagtt cggcttcgac ttgaggaatt cctgagcctt
    13261 taatatcttt ttctgaccgt gttagtttgg cactgagcca acagatgagt atataaaaca
    13321 aaaccagtac aaaaagattg cgcactaagt acccttgatc ttgataaact ccttgtatca
    13381 ggtggaagcc cttttcaatt aagaaacgaa aggatccgac gataattcca acgatgaggc
    13441 cgacaatgat tcctcgacca acttgggata gtatagtgct ggatgcaaag gcgaattctt
    13501 tcttagaacg gactatttcc gactgttcct ccatggtatt tcctttcaat taattttctt
    13561 ttttacctaa aaccagtgat ttaacgggtt caaagctggt tcggtgaatt ggggtaactc
    13621 ctagttttgt gaggccttcc agatgtttag ctgtgccata tcctgcatta gtagcgaaat
    13681 catagccagg gaactgctga tcgtattcct tcatcaattc atcacgtgtt accttggcta
    13741 ctatagatgc tgctgcgata gagagggagt tggcatctcc tttgataatg gaggtttgtg
    13801 aaatgggcaa gtccagtttc atggcatcaa tcaaaaggtg ctctggttga gggctgagct
    13861 gggagattgc ttcttgcatg gctagtttgg ttgcttcata gatgttgact tggtcgatga
    13921 cctgattatc tatgatacca attccaatcg acaaggcttg gtcttgaacg gcttggaaaa
    13981 tctccagatg tttcttttta ggaattttct tgctgtcgtt gagaccttta atcttacaat
    14041 ttttaggtaa aatgacggcc gcagcgacta caggaccagc aagaggacca cgaccaacct
    14101 catcaatacc tacaattaag gtcaatcctt gcttataaag ttctttttca taagaaagca
    14161 tggattccaa gcgcaaattt tcatctaatt cagcttgaat ggctctttta cgcttgctga
    14221 tttccttttg aactcctgag cgattatcct tttcaagctc taaaaaaata gggctttcta
    14281 actccttgac tgtcacaagg agttctttga tttctttaat cgttgccatc gaggtcttcc
    14341 aatgtatcta aggtatagtt accgagtttg ccatcacgga cttccttcac gaagagactg
    14401 taaaaacggt catagtcatc acggaaaccg agggcgcggg tcatatccat aataatcaca
    14461 ggcgcttctt cttcaatttt catttgtttg aagcgttcag ccagcttttc tggataatgt
    14521 tctttgaaat aattgatacc aaaaatggta acctcatcca taggaagcaa ctgatccttg
    14581 atagctccag tcaatgccaa cttaagtgca acagtttcat cctcaaactt aggccagaga
    14641 atccccggtg tatccaagat ttccagatct ttattggttt taagccattg ttgacctttt
    14701 gtgacccctg gcttgtttcc aacaacagca atctttttac cagccaaacg gttcatcaga
    14761 gtggatttac cagcgtttgg aatcccgata atcatggtac gcaaggtttc aatctgaatc
    14821 ccacgttctt tctggcgagc aatcttatca gccatgagct tcttggccgc atctgttaca
    14881 acttttacag tcacttgctc tttggagttg atagctagcg tctggatttc ttgtgattca
    14941 aaatactgac accattcctt ggtcattgct ggatcagcca agtcggcctt gtttaaaatc
    15001 aagagttttg gtttatcacc aacaatcttg gtcaacatag gattttgact agatagaggc
    15061 aagcgtgcat ctactaaaat cgtcacaaaa tcaacaaatt ttaaattttc ctgcacctgt
    15121 cgacgcgctt tagacatgtg accaggaaac cattgaatag tagccattga gttttttcct
    15181 ttcgtagctc tgaagctgtt aatctagaac taagagatct caatctaaaa atgaatgatg
    15241 tccaaacagt tcttgtttta tgatataaaa atctacttta tattatatca tgccttcttt
    15301 attttgtccg atgatagcct tttaccctat cttttaccct atatagaaaa aagccatcaa
    15361 atgatgactt ttcagaggga gcaaaaaact gtcctcttta tattttaaac atttaaatgt
    15421 cttctttaaa cagtttatta aagaaaccgt ctgtgttttt aagaagggct ttgaatactt
    15481 tggatttcaa gtctactgta tttttgaaat gatctttaat tttcggatct gacataccat
    15541 caatatcttt ttgaacagct tcagcaaata aagttttcaa ctgagcataa tttgtaattt
    15601 gacgaccatc aatttcaata gcagtaaatc ctttttctgc ttttgactta acatctttga
    15661 agtattgttt cttccactct tcaagattat tgaatttatc cttagatact ttcttgataa
    15721 tgaaatcatc acccaataat tttttattgg ttttgtcagc ttcgccttga tatttgctag
    15781 atgcataact aatgaatcca ttttcataac caaaatagcc ccacatacgg aaagtattat
    15841 gcttgaatga tgcagctcca ggtgctcctt ggctagtatt accaccatag ataccggtca
    15901 ttatattaat atttacgtaa gcactatcaa aatcttctgg attatatgtt ctgtcactag
    15961 gagcgccatg ttttgtcatc aaattattgt tgactaaatc atcaatgttg ttgataacaa
    16021 ttttcttctt ctcatcttca gttaattcac gaactttatc aaattgatgt agctctccat
    16081 ttttgcgata ttgtctatcc attttcttga accatcgact aatattacca tgtaatttag
    16141 ggataacagc atcagcctca agatggtcta acatcataag agcatcatta taatttctca
    16201 tataacggtc gatatcttca cgagttttca atttatctgg atcataatta taccattggt
    16261 caccgtcatt ttcacgatga taagccatgt taagaccaag agcaccatat tcaccgttac
    16321 cagatttatc aggtgtctgc aacatacctt gcgcataggc ttcaacgtct gtaccttgac
    16381 ggtgtctatg cccaccgaag taaagcattc tatcgtttac gtgtgttgtt tcgtgagtaa
    16441 aggctgaaat accaaacgga ctaatcatat ttgttcccat gaaataaact tggtcattat
    16501 tattgggatc ttggaaaata gatgccatag ctcccatgta ccaatttgta gtatgataac
    16561 gccaagtagg tccatataat tcacgaatag gtgcaattgg tttattattc ttatcataac
    16621 ccatacgatt tacaccttcg acgttatgat agttttggtt atcccaaaca ggtgttggaa
    16681 ccctattttg actcttgagt aattggtcac gtacgcttgg caatgctaaa cgcgaccaga
    16741 agtcaagata agtttgttgt gcgtgagcaa cttctttaat tttatcttta aatgcttctc
    16801 gttcagcttc tgtatactta ccatattttt caaaagagct ataagccatt gtattgtaag
    16861 tcgaaatcaa gaacatatgt gcattcttaa gagttaatag aggtaggatc atacgattat
    16921 gaacaccatt attcaaacca tcaaatgcac gatgtcgttt attaacaaaa tctgggttcg
    16981 ttgttttagg ctccacaatg tatacgttct tagccgcatg gataaaccaa tcatttaaat
    17041 cagtatcgtt agtgaagaga cgcatgttgt aatctaagaa gccatgtaat tcagacttac
    17101 caatagttcc accaatcata tcacgataag catccaaagt tctgtcaccc ttgatatttc
    17161 gctcacttga tccaattcga atcaagaagt caagaaggtc aactgactta ccatagaaat
    17221 caggtttaaa catcatcaag tttttgatag tcatatcccc atactttata tcatagtaac
    17281 gattaaggta agtaagagcc atcacgattt tagctttatt ttcatccacc ttcttaacaa
    17341 gtgctttcat agctgcttcg tcactattta attgatggtc agcattttca atcaaagatt
    17401 tgaccaattt atcaagatta gctttcgttt cagaaaaact ttcttcgaaa taaaggtctc
    17461 ggatataacc attcttacgc tcatccgaat tagcattagg atctctagat gtatctcgtt
    17521 tatccatcaa agcacggact tcgggagaaa ttaattcaac agttgctaac ctatctttaa
    17581 tgtctttaat caattgatca cgatttttat caaccatgtt tggtgtataa acaatgtcat
    17641 ctaatccatc gatactatac tcacgaactt gcgctacttt agactctttt tgatgaacag
    17701 ctttgatttc tttagtctta tctgcatagt gaatcatcac atgatcaata tctgataaat
    17761 cggtcacgaa ttgaccatcc ttcatacccg taacagaaag gacttctttc ttagctaagt
    17821 ttgaatcttc tgcaagtttg ttaccttgat tgacaatcca ttctttgtta taaaatggtt
    17881 gcagtttctc aatattacga taagccagat ctcgatctac tttatagtct tgggttgact
    17941 tatattcatc ttctcttctg gttaaacgat ttaagcgatt gaccacaggt tcattgattt
    18001 cgtatttatc tgcggtaatt cctgtagctt caattttaga ttttgcctct tcctcagaaa
    18061 taggtctgat acgattttta tcttttgaac gctggtagct agaatgccca tcactaacac
    18121 ctattacaac ataatttcgt cttacattat ctcctgtcca gtagccatca tcataatcaa
    18181 tatcactaga accatagaaa atttcaccat taggtacctt catcatggaa actgaatctt
    18241 cgacagaacc gtggtgcttc atgcttccta caacaccacc actttcaatc gcctcagtta
    18301 cttgaattgt tcccttagca atagattttt tgattgctcc ttcctgacga acagtattgt
    18361 tatttccttc attttgtgtc caataagcaa tgcccgcagc cttggctttc ttgccaataa
    18421 gatttgcgtt aacatacgcg cgttcgacga gtcctttcca gttctcacca acgataccag
    18481 tcaagaattg tccaccatcg ccgacagaag ttacgttacc gataaaggcc acatttctga
    18541 gtgtaccttg gttatcaatc ttatcaataa atccagatac ccaatcttta cctactatat
    18601 tacctttaac cttaacattt tcaatggtag ttccaccttt aataatattc gctacagctg
    18661 caacttggtt cgcccatggc atatttatgt caacattacc aagattaata ttcttaatcg
    18721 ttccaccaat aacattgcca aataacggac gtgacaagtt atgaatggta tagtgattat
    18781 caccatcact caagagctta cctttgaaat ctttcgtaac atatgattta ccaaatgctg
    18841 atacatttgt ggcattaagg tcagcaccca atttaaactc gtcatttgga tgttcttgca
    18901 tatctctcac aagttcattg aaattgtaat atacattatt gacttttgga actggttttt
    18961 caatgtaatg aatgtattca tttctagtct tagatggatc gacatgttga attaaatctt
    19021 gagcgcttgc tgtaatttta taaagttctt tttctttttc agttactaac tcaatcttat
    19081 caactgctaa acgagttact ttattatcac gactagtgat ttttaagtac attttcttca
    19141 catcttcatc agaaggtttt tcgctcatga aatcactagg tatttcagta ccatcatcat
    19201 ttaccttcac taaattagta gatgaaatat ttttaatttc gacctttttc aactccaaac
    19261 gcaaagtttt ttcatccagt ttagacgttt cagaaccttg accacgatca taaatcattg
    19321 ttgttgcaat cttataatct ttaaacaaat ccaaattttg tacagcgtca gttaattttt
    19381 ctttagataa atcaaccttt ttaactactg tatcaccatc tttaatttca gctataatac
    19441 ttgatatttc agcattatct ttattatcaa gctcataatt taagttggca gaacgattca
    19501 tagcatcttc tgttactttg gtcaaggtca aaacgggaac tgttttttct tttggatttt
    19561 cttttgtacc ttttacaaga attttaggtt tcatttcttt caaaattgtt accgtttcaa
    19621 ctggttcact aatttttttg ccatgtaact cttcatagct agtaacaatt tgacgttcgc
    19681 catcctcacc aacttcttta acagaatcat cgcctataaa tttgctagga tcagattctt
    19741 ctatagtggt tttaggaata gtctctgtac gaatatcggt atgtaaagaa ggcaactctt
    19801 ctctttctga tgcaacttct gaaactgtag atattggttc agtatactct ggaatgtcgt
    19861 taacaggtgg ttcaatcaag tttccatttt catccactcc tgttgtacct actggttcag
    19921 tgtatgctag tttctcatga acttcaggct caacaaggtt tgcacctatt ggttgcgtat
    19981 agtcaggctt ctcatgaact tctggttcgc ctttgtcagt cacaacagct tctggtaatg
    20041 tcggttgtac ttccggttcg cctttgtcag tcacaacagc ttcgggtaag gctggttgaa
    20101 cctccggttc ccctttctct gttacaactt tgggttgctc aactggcgaa acagttgatg
    20161 ctggagaaac cgacgaaaca gttttatcat caagctccaa gtaaccaaca tatctgtaac
    20221 cagaaatttg caacacacca tcacgtccag actcatggat gttagcattc aaattaagtg
    20281 ctgaagcagt tgatagtgta actaaacctg tcgcccctac aatcaaaaat gtagctattt
    20341 ttttatttct attatctttt gtgataatca caataagact cccgatagct aacaaaccca
    20401 atgcagtcat aatagattga gaactgcctg tgtttggtag tgcgtctttt tcataatcca
    20461 aagcatatga ctctttggat tcatcaggtc taccttgttt gagttgatca cgttcagttt
    20521 gtgtcaaact actataatct aagtaatgat aagtcgatgc accaataact gacggtgcaa
    20581 ataaaagact ccccaagaat accgaaccaa caataccctt tattttccga atggaaaatt
    20641 tatctttttt taataatgac aattctaatc ctccacattc actttttatt tcctaatagt
    20701 aaacactatt ttttattctc aaaaattgaa cttctaaaat catttgtttg gtcaagataa
    20761 gctttatata ttgctttttt cagtttaaga actctactat ttgtttctgg gtaaaatttt
    20821 gctacgtcat cttgcgcatc atctctcact gcttcgacaa tcattctctc tagtacacct
    20881 atatccgtaa ccgatacatt tcgttgacga ctcaatggat tattaggatt aataaagtta
    20941 actctattta gtttactgaa ttgtttttct ctttccttat acatatcctt cttgaattgt
    21001 gtccaagttt tatattgacc attaaatact ttttcaagta ctaattcatc tgtaactaaa
    21061 cctacttctt taccataaga attaatctta cttcccgccg cttttgcatc tttttcatat
    21121 tgatttgaga tataaggtac catgccctct ttatatcctt ttgcagctaa taattcgaat
    21181 gctatacggc gtcccattaa atcaccagga gtccctttct ctccactaag agctgaataa
    21241 atcggtgaaa ataaatcaat tgtataataa ccatttctct tatattcttg gtctttgtac
    21301 cctctgctag taataatatc attttcaatt aaactatcaa aagaatttaa tttattaact
    21361 tcatccatcg ttaatctgcg aacaacattt gtcgcgtata cattattacc gtcttgatca
    21421 agatcaaatt tattttcaat ttttcttagt aactcatatt tttgatttgt ttctaaatta
    21481 gctacagctt ttccttctaa atattctaac atataaatta catcaaacat attatgcata
    21541 taattatgta ggtcttctgc actattaaat cgttgagttg gatcagctac ttgaagtctt
    21601 gttgaatttt ctgaatcctc atatttcaag acagagttaa ttgttattgt tggatcatat
    21661 ggatgatccg gagcttgtaa taatcctttt gcataaaact caggtcctaa tccgcttctt
    21721 cttccatatc ctccaagata aatctctcta tctgagttat gtgtcatttc atgagtatat
    21781 gttacagctc catctttatc caacatacga tatgccatat aatagaatgc atctccggta
    21841 gcatatgctc cgtgtccatt atgaacaaca ttatttcccg caggtccaaa gaagtatttt
    21901 atagctggat gatcagtttc aaaagtagct tgatgagtta ctttgtcttt atctttgtca
    21961 gtaccaaatt tgaaagcatc atatactaga atacttctat ataatttttc tttattatcg
    22021 ttatctaata tcttatacca ataatcataa tgatctctaa atcgtttagc cgcttctttg
    22081 gcgttatctt ctacaaattt gtttaacttt tctcccttag gatattctga acttctatat
    22141 ctgtcatagg ctccaaatcc aatagtagaa atattcgcta tcataaacac tgttttttct
    22201 tcaggtaaag ttaatagtgg taagaccata ctttgatatt tccaagatgg attagttaat
    22261 ctatcatata ccccaataga atatttagtt ccctcttttc cttgtttttc tcttccctct
    22321 tcaattgtag atttttcttc tacaatatat gcttttgttt gttttttaaa ccactcattg
    22381 ttagaaattg ttggtaagaa tacttttcta tatccttcta atgctttaaa taaactttca
    22441 gttccataat ttttcgctaa taatacatta taagtaatta cattattttt tgctaataaa
    22501 ttgttaaatc cagatttacc taa
//
LOCUS       DAVKEV010000036        22237 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVKEV010000036 DAVKEV010000000
VERSION     DAVKEV010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22237
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.036"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..928
                     /locus_tag="VWZ68_001527"
     CDS             <1..928
                     /locus_tag="VWZ68_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEU9372535.1"
                     /translation="TDYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKSTVPIGFSNK
                     LKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVVGDETVEGRKIAELFLSISTHSTAN
                     IKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDFFAERRSLNAEVVIKGVCLDPRIG
                     NFYNNPSFEFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNTNRKQFIVKQILERKPK
                     IVGIYKLGMKYNSDNYKESAILSIINELLIVGIKILVYEPNLNVSIDNVIFEKNFELF
                     TKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            1323..2186
                     /locus_tag="VWZ68_001528"
     CDS             1323..2186
                     /locus_tag="VWZ68_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU9372536.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TLPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFLYIPIFE
                     AELESMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFTQSLQVLENPQLTSLFE
                     LRLQQYKKLID"
     gene            2472..2669
                     /locus_tag="VWZ68_001529"
     CDS             2472..2669
                     /locus_tag="VWZ68_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEU9372537.1"
                     /translation="MLNLQFAETMELTEAELETGYGGEFGNNAVIPAGAWGGLGTSWS
                     ITNFWKKYFNHDSSTVNRRHY"
     gene            2737..3402
                     /locus_tag="VWZ68_001530"
     CDS             2737..3402
                     /locus_tag="VWZ68_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9372538.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            3474..4700
                     /locus_tag="VWZ68_001531"
     CDS             3474..4700
                     /locus_tag="VWZ68_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9372539.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLT
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(5050..5127)
                     /locus_tag="VWZ68_001532"
                     /pseudo
     CDS             complement(5050..5127)
                     /locus_tag="VWZ68_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            5198..5854
                     /locus_tag="VWZ68_001533"
     CDS             5198..5854
                     /locus_tag="VWZ68_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEU9372540.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTLVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            5844..6167
                     /locus_tag="VWZ68_001534"
     CDS             5844..6167
                     /locus_tag="VWZ68_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEU9372541.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMIPFILVKHKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            6270..7100
                     /locus_tag="VWZ68_001535"
     CDS             6270..7100
                     /locus_tag="VWZ68_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9372542.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYNVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            7254..8108
                     /locus_tag="VWZ68_001536"
     CDS             7254..8108
                     /locus_tag="VWZ68_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU9372543.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            8208..9581
                     /locus_tag="VWZ68_001537"
     CDS             8208..9581
                     /locus_tag="VWZ68_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEU9372544.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            9574..10635
                     /locus_tag="VWZ68_001538"
     CDS             9574..10635
                     /locus_tag="VWZ68_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEU9372545.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGSSTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            10637..11329
                     /locus_tag="VWZ68_001539"
     CDS             10637..11329
                     /locus_tag="VWZ68_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9372546.1"
                     /translation="MESLIQTYLPNVYKMGWSGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAIPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(11358..11927)
                     /locus_tag="VWZ68_001540"
     CDS             complement(11358..11927)
                     /locus_tag="VWZ68_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU9372547.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            12062..12676
                     /locus_tag="VWZ68_001541"
     CDS             12062..12676
                     /locus_tag="VWZ68_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU9372548.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            12678..14324
                     /locus_tag="VWZ68_001542"
     CDS             12678..14324
                     /locus_tag="VWZ68_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9372549.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            14336..15622
                     /locus_tag="VWZ68_001543"
     CDS             14336..15622
                     /locus_tag="VWZ68_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9372550.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            15674..16207
                     /locus_tag="VWZ68_001544"
     CDS             15674..16207
                     /locus_tag="VWZ68_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9372551.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            16285..16755
                     /gene="nrdI"
                     /locus_tag="VWZ68_001545"
     CDS             16285..16755
                     /gene="nrdI"
                     /locus_tag="VWZ68_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEU9372552.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(17048..18310)
                     /locus_tag="VWZ68_001546"
     CDS             complement(17048..18310)
                     /locus_tag="VWZ68_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEU9372553.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIIIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(18620..19078)
                     /locus_tag="VWZ68_001547"
     CDS             complement(18620..19078)
                     /locus_tag="VWZ68_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEU9372554.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(19075..19515)
                     /locus_tag="VWZ68_001548"
     CDS             complement(19075..19515)
                     /locus_tag="VWZ68_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9372555.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            19948..20814
                     /locus_tag="VWZ68_001549"
     CDS             19948..20814
                     /locus_tag="VWZ68_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9372556.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLNALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            21151..21708
                     /locus_tag="VWZ68_001550"
     CDS             21151..21708
                     /locus_tag="VWZ68_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
                     /protein_id="HEU9372557.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            21929..>22237
                     /locus_tag="VWZ68_001551"
     CDS             21929..>22237
                     /locus_tag="VWZ68_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HEU9372558.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     F"
BASE COUNT         6718 a         3881 c         4799 g         6839 t
ORIGIN      
        1 gacagattat gatgagaaaa ttggtagttt taatacatat gaaatcgaac aaacggtatc
       61 gaagattctg agggtaaaac ctaatggaaa gattatttta aagtcaacag ttccgatcgg
      121 cttttcaaac aaattaaaaa ggctgtttga tacaaaaaat atcatttttg tccctgaatt
      181 tttgagagaa ggttgttcta tatatgataa tttatatcca agtcgcatag ttgttggaga
      241 tgagacagtt gaaggaagaa aaattgcaga gttgttcctt tcgattagta ctcatagtac
      301 tgccaatatt aaaaatgtta tgttagtttc tcctactgaa gcagaagcaa ttaagctttt
      361 ttctaacaca ttcttagctc tccgtgttgc tttttttaat gaactagatt tttttgctga
      421 gaggagaagt ttaaatgctg aagttgtaat aaaaggtgtt tgtttagatc caagaattgg
      481 aaatttttat aataatcctt cttttgaatt tggaggatat tgtcttccca aagatactaa
      541 acaattaaaa aaagaattta tagaaataaa tgccccagtg atagaagcga ttgatatttc
      601 aaacacaaat agaaaacagt tcatagttaa acaaatattg gaacgaaagc caaagatagt
      661 aggaatatat aaattgggga tgaaatataa ttcagataat tacaaagagt cagctatttt
      721 aagtataatt aatgaactat tgattgtcgg tataaaaatt ttagtatatg aaccaaattt
      781 aaacgttagt atagataacg taatttttga aaagaatttt gaactattta caaaacaaag
      841 tgatctaatt gttgcaaata gatgggatag gggccttgaa gcttataaag ataaagttta
      901 cacaaggggg atctggataa gagattaact attgatatta aaaaggcaat aatttataaa
      961 atttgtacaa aaaaatgtta aattttcaca ttttcatagt atactgttta atagaaagta
     1021 ggttctttgt aaccgctcca ttataaaatc ctttcactct tccggtatgc tattaggaaa
     1081 aacataattg gaggatattt tgagctcaca cctcatcgtt ccagtggctg ttccccaagc
     1141 tcgtgtactg cccaaaaaag ttagacattc tatttagaac gaggattgag ttctgtattg
     1201 tacaaggctc ggtcctttta gagtcagctt aaggctggct ttttcaatca ccaaagtgtc
     1261 agaatgtttt gacaaatgaa cacaaataat gatataatat gcaaaagcta ggaggtggta
     1321 ggatgattga aaaaatggaa ctgggggaat tttacaagga attacgtttg gcgagaaagc
     1381 tcaagcagtc agatgtggct tgtgacgggc taacagcttc tcagttgtcc aagtttgagc
     1441 tagggcagtc catgttgtct gctgataagc tcatattagc catccaaggg atcaatgtga
     1501 cctttgatga gtttgggcac aagctcaaca actatcaaga atctccacat atgcagattg
     1561 gtagaaaggt tgtggatcgc tttgctcatc aagatatagc tggcttagag caactgttgg
     1621 aggaagtcga gcaagaacag atggcagaga cttatcgtcg tttgaatgct attgtaatca
     1681 aagatgccat ccactcacta gataaaagct acccactagc agaggaggat agcgagtttt
     1741 tgaccaccta tctctatgct atcgagtctt ggacctggtt tgaactctat ctcttttgca
     1801 atactctgcc cttcttgagc aatcaagatc tgatcttttt atcaacctcc ttactcgaaa
     1861 aatccaaaga atttaaagag ttagtacaca atcgattgta tatgaagcaa ggactcttaa
     1921 atatcttatc agaactcatg gagcgaaaac ttttcttata catcccaatc ttcgaagccg
     1981 agttggagag catgttgcgt ccgtacgatg tttttgaaaa agtatcgtgg caatttttaa
     2041 agaagatgag tgtctttctt caaacaaagg gaagcaatca aaaagagatt gaacgcttta
     2101 cccaatctct gcaggtatta gaaaatccac aattaacatc cctttttgaa ttgcgtttgc
     2161 agcaatacaa aaagcttatc gattagttag aaatggcaaa ataataataa tctcagcaac
     2221 gatcgtcaat aatgttaaaa cttgtttctt catattactt ccctcctcat tagtaataac
     2281 tttattatac cagggaaata atcaaatcta ccaaaatcgc aaatctgaaa tttctataag
     2341 aaaaaatatc aaatatgcga ttttctaaaa taagccaatt tccgtgttat actgtccttg
     2401 taaaacattt gaagcaaatc ctaggtcgca gaagtggttt acaaatgaag ataattgaag
     2461 gagtgtaaaa gatgttaaat ttacaatttg cagaaacaat ggaattgaca gaagctgagt
     2521 tggagacagg ttatggaggg gaatttggga ataatgctgt tatcccagcc ggtgcttggg
     2581 gaggtttagg aacgtcttgg tcaatcacta atttctggaa gaaatatttt aaccatgatt
     2641 cttccactgt taatcgtcgc cattattgat attcagagtc cttgcctttt tcttgggtag
     2701 ggactgtctt tatttcatag tataggagaa aatagaatga aaaagataat ctcacaccgc
     2761 tactttatta tagtttttct actagttatt gctgaccaga agttcagtgt tttagtttta
     2821 cgcagcgacc ttgttgctgg gctatctgac tttgcctatt atctgtcgga tatgatgttg
     2881 aattttcttg tggttttatt tgctcttatt gctatgattt ggtcggggaa atggcagaaa
     2941 atcaatagta gaaagtttaa aggatcctat cttttctatt ccttcctagc tctgcttgct
     3001 tttgttgctt ggaattttgt cacctttttt cttttcccac ctactcgaaa tgaaatttct
     3061 tatcaacatg ctgctcctac ttttacagga gctacggcat ttttgatgta ttttttttat
     3121 cctgtgattg caggtcccat ttttgaagac atgatttatc gtggattagt gatgactgct
     3181 ctggaaaaag gaaagaaatg ggggctagat gtacttggtt ccgctgtttt atttggggtc
     3241 tcgcacatta gtaatcacgg ttgggtcttg acagactttg tcttctatat gggtggaggt
     3301 cttatatttg cagtcttatt tagaatgaca aagtcaattt attggcctat tggactgcat
     3361 atagtctaca atggcattgg tcagcttttg atgttactgt aattttggtt gttagtagta
     3421 tcgcggtcta tccttgggga aagattccca tttgaactta agaaggagtt gtgatgaaag
     3481 tatttcttca aaatagagat tttaggcaat taactatcaa ccagtggatt tcaacgcttg
     3541 gggatacgat tttttatctg gcctttctga attatgtggc agatgcgtct tttgcacctt
     3601 tgacgatttt actcattacg atttcagaaa cccttcccca aattttacaa atctttctgg
     3661 gagttttggc agattttcaa catcatcgtg tcttgaaata cacagtcatt agttttgcaa
     3721 aatttttgct ttactctatc gtttctttat cactttcagg gcagtctttc tccttgttgc
     3781 tagtagcatt tatttgtctg cttaacctct tgtctgacac attgagttac ttttcaggag
     3841 ccatgctcac tccgattttc attagaatta ttgggcaaga ccatctggca gaagctattg
     3901 gctttaaaca gtcaactgtt agtttagtga aaacaatcag taatatccta ggaggagtct
     3961 tactaggcat tctatccatc cagtttattt ccttactgaa cgctcttacc tttttaatcg
     4021 catttttagg tatcctcttc ataaaaactg acctcttgaa agtagaaaaa acgattagct
     4081 atcaagaagg actctctgta aaatcctttt gccagcattt gctccaatca tcaaaattga
     4141 tatggaatat gaataaggtg ctcttggttt tgtttattat ctctactagt caagcagtga
     4201 taaatgttac ggttcctatt tccactctat ttttaaggaa ccagcccttt ttgaatttac
     4261 aaacaggtca atctcttgcc ttgctatcca cttttgaact gtcagccctg attgtcggaa
     4321 gccttgtaag tggctatctg caacatacca tttccataaa aacagctctc tatgcctcac
     4381 ttgtcatcca gttgcttctt ctagtaggat ttgccacagt tcgttttgac tggattctca
     4441 tctttagtac cttggatgcc tttttcgcag gtgttctctc tcctagattg caagaactcg
     4501 tttttaaaca aatacctgag gagtcaatgg gagcagttca atcctctatc ggtgccatta
     4561 cggttgtttt acctagctta tttacaatag ctttggtaac cattgctact agctttggaa
     4621 ctctggcagt tagctttgtt ttattgctat ttcttctagt tgcctttgtt atgcttctga
     4681 atattcgtga aagtatttag tggagaattt ctataatata tgtttgagac tggattgcca
     4741 gtctttttat gatggtcaaa atcaacagac tttttctctt ttctgaatgt gttatagtag
     4801 actgaatcta aaatagtacg aaacaattgc taaaacattt atagaaatta attttacttt
     4861 cccaatcgat ttgttctcat cttatttcaa tctgctatat aatagtccat gctgtggctg
     4921 gattcttttc agcctacttg tactcttcga aactctcttc aaaccacgtc agcttcactt
     4981 tgccgtagta cggttactga cttcgtcagt tctatccaca acctcaaaac agtgttttga
     5041 gctgacttcg tcagttctat ccacaacctc aaaacggtgt tttgagcaac ctgcggctag
     5101 tttcctagtt tgctctttga ttttcattga gtattattaa gacaatatga ggagaaagat
     5161 gaaagaaaaa ggattttagg agggggcgca ggcagccatg ccaacggctc ttggctatgt
     5221 cagtatcggc ctggcctgtg gaattatcgg tgcgccctat gtgacacttg ttgagatggg
     5281 cttgatgagt ctctttgttt atgctgggag tgcccagttt gccatgttgg cactgattgt
     5341 ggttcaagct cctgtggcag ctattgctat gacggttttt ctaatcaact tgcgtctctt
     5401 tttgttgagt ttacacgcat cgacttattt ccgtcatacc agtctttggt acaatatcgg
     5461 tatgtctagt atcttgacag atgagaccta tggcgttttg atgggtgaat tggcccatac
     5521 agacaaggta aatcctatgt ggatgcacgg gaacaatctc aacagctatg tggcttggtt
     5581 tgtggggaca gtagtcggaa cggctctggg tggcctgcta ccaaatccag aaatctttgg
     5641 cttggatttt gccctggttg ggatgtttat tggtattttt gcttcgcaat ttcagattat
     5701 gcaaagacgg attcctgtcc gcaatctgct cattatccta gcagttgttg cggtgtcctt
     5761 ctttttgctc ttgacagtgg tgtctcagtc actagctgtt ctgtttgcga cgctacttgg
     5821 ttgtagcatg ggggtggttt tagatggtca gtaagtatct tttattagca gttattttct
     5881 ctggtcttgt gacctggatt ccccgtatga ttcccttcat cttggtcaag cataagggcc
     5941 tgcctgcgat tgttgagcgt tttttgaagt ttttgcctgt ttccattatc tttgccttga
     6001 ttctttcaag cgtagtgaca ggtaaggttg ggagccttcc tcaaattaaa tggctagact
     6061 tcttagccgt ctttccaaca gcttgggtag cctttcgcta ccgcaatcta gtcggaacag
     6121 ttctctttgg agtggtcttg attgccatct tgcgtttggt cttttaaatt acccataaaa
     6181 aaacttatca cagagataga tatcatataa tggcgtaaat gctctttttc tgttaagatt
     6241 ataaggtatt ctattttgga ggaaatgaca tgaaaaaaat cgttaaatac tcatctcttg
     6301 cagcccttgc tcttgttgct gcaggtgtgc ttgcggcttg ctcaggtggt gctaagaaag
     6361 aaggacaagc agctagcaag aaagaaatca tcgttgcaac caatggatca ccaaagccat
     6421 ttatctatga agaaaatggc gaattgactg gttatgagat tgaagtcgtt cgcgctatct
     6481 ttaaagattc tgacaaatat aatgtcaagt ttgaaaagac agaatggtca ggtgtctttg
     6541 ctggtcttga tgctgaccgt tacaatatgg ctgtcaacaa tcttagctac actaaagaac
     6601 gtgcggagaa atacctctat gccgcaccaa ttgcccaaaa tcctaatgtc cttgtagtga
     6661 agaaagatga ctctagtatc aagtctctcg atgatatcgg tggaaaatcg acggaagtcg
     6721 ttcaagccac tacatcagct aagcagttag aagcatacaa cgctgaacac acggacaacc
     6781 caactatcct taactatact aaggcagatt tccaacaaat catggtacgt ttgagcgatg
     6841 gacaatttga ctacaagatt tttgataaaa tcggtgttga aacagtgatc aagaaccaag
     6901 gtttggacaa cttgaaagtt atcgaacttc caagcgacca acaaccgtac gtttacccac
     6961 ttcttgctca gggtcaagat gagttgaaat catttgtaga caaacgcatt aaagaactct
     7021 acaaagacgg aacgcttgaa aaattgtcta aacaattctt cggagacact tatctaccgg
     7081 cagaagctga tattaaataa tttcttgaaa tcatccattc tgagtaagat gggtggtttc
     7141 tcagttttta gggatatagt tttaaactat atatctgact atctaataac aatttgtgaa
     7201 atcaaacaaa ttgtgagata ctagtacggt attattttta aggagaaaga atcatgaaaa
     7261 tcaaaaaatg gcttggccta gcagcccttg ctacagtcgc aggtttggct cttgcagctt
     7321 gcggaaactc agaaaagaaa gcagacaatg caacaactat caaaatcgca actgttaacc
     7381 gtagcggttc tgaagaaaaa cgttgggaca aaatccaaga attggttaaa aaagacggaa
     7441 ttaccttgga atttacagag ttcacagact actcacaacc aaacaaagca actgctgatg
     7501 gcgaagtaga tttgaacgct ttccaacact ataacttctt gaacaactgg aacaaagaaa
     7561 acggaaaaga ccttgtagcg attgcagata cttacatctc tccaatccgc ctttactcag
     7621 gtttgaatgg aagtgccaac aagtacacta aagtagaaga catcccagca aacggagaaa
     7681 tcgctgtacc gaatgacgct acaaacgaaa gccgtgcgct ttacttgctt caatcagctg
     7741 gcttgattaa attggatgtt tctggaactg ctcttgcaac agttgccaac atcaaagaaa
     7801 atccaaagaa cttgaaaatc actgaattgg acgctagcca aacagctcgt tcattgtcat
     7861 cagttgacgc tgccgttgta aacaatacct tcgttacaga agcaaaattg gactacaaga
     7921 aagcactttt caaagaacaa gctgatgaaa actcaaaaca atggtacaac atcattgttg
     7981 cgaaaaaaga ttgggaaaca tcacctaagg ctgatgctat caagaaagta atcgcagctt
     8041 accacacaga tgacgtgaaa aaagttatcg aagaatcatc agatggtttg gatcaaccag
     8101 tttggtaata agaaacaggg aggtgggaga gaaaattcca cctcttgctt ttgtatagag
     8161 tatagattgt aaagaagact attcgttcat agaaaggtag agagaatatg gtttttccta
     8221 gcgaacaaga acagattgaa aaatttgaaa aggatcatgt agtccaacat tattttgagg
     8281 ttttgcgtac cttgatttct aagaaatcag tctttgccca gcaggttgga ctcaaggaag
     8341 tcgcaaatta tctgggtgag attttcaagc gtgttggagc tgaagtggag attgatgaga
     8401 gctatacagc gccctttgtc atggcacatt tcaagagttc gcgtccagat gccaagacct
     8461 tgattttcta taaccactat gacactgtgc cagcggatgg ggatcaggtc tggacagagg
     8521 atccttttac gctttcggtc cgcaatggct tcatgtatgg gcgtggggtt gatgacgaca
     8581 agggtcatat cacagctcgc ttgagtgctt tgagaaaata tatgcagcac catgatgatt
     8641 tacctgtcaa tatcagcttt atcatggagg gagcggagga atcggcttca acagacctag
     8701 ataagtattt ggaaaagcat gcagacaaac tccgtggggc ggatttgttg gtctgggaac
     8761 aagggaccaa aaatgccttg gaacagctgg aaatttctgg tggcaataag gggattgtga
     8821 cctttgatgc caaggtaaaa agcgctgatg tggatatcca ctcgagttat ggtggtgttg
     8881 tggaatcagc tccttggtat ctcctccaag ccttacagtc tcttcgtgct gcggatggcc
     8941 gtatcttggt tgaaggcttg tacgaagaag tacaagagcc caatgaacga gaaatggcct
     9001 tgctagaaac ttatggtcaa cgaaacccag aggaagttag tcggatttat ggattggagt
     9061 tgcctctctt acaggaggag cggatggcct ttctaaaacg tttctttttc gagccagcgc
     9121 ttaatatcga aggaatccag tctggttatc aaggtcaggg tgttaagact attttacctg
     9181 cagaagccag tgccaagcta gaggttcgtc tggttccggg cctagaaccg catgatgttc
     9241 tggaaaaaat tcggaaacag ctagacaaaa atggctttga taaggtagaa ttatactata
     9301 ccttgggaga gatgagctat cgaagcgata tgagcgcacc agccattctc aatgtgatcg
     9361 agttggccaa gaaattctat ccacagggcg tttcagtctt gccgacgaca gcggggacag
     9421 gacctatgca tacggtcttt gatgccctag aggtaccaat ggttgcattc ggtctaggaa
     9481 atgccaatag ccgagaccac ggtggagatg aaaatgtgcg aatcgctgat tattacaccc
     9541 atatcgaatt agtagaggag ctgattagaa gctatgagta gagatattat caagttagat
     9601 cagatcgatg tgacttttca ccaaaagaag agaaccatta cagcggttaa ggatgtgacc
     9661 attcacatcc aagaagggga tatctacgga atcgttggat attctggagc aggaaaatca
     9721 acccttgtac gggtgattaa tctcttgcaa aaaccatctg cagggaaaat taccattgac
     9781 gacgatgtga tttttgacgg caaggtgacc ttgacggcag agcagttgcg tcgtaaacgt
     9841 caagatatcg gaatgatttt ccagcatttt aacctgatga gccaaaagac agcagaggag
     9901 aatgtagcct ttgcccttaa acactctgaa ctcagcaagg aagaaaagaa ggctaaagta
     9961 gctaagttgt tggacttggt tggtttggca gatcgtgctg aaaactaccc ttcacaacta
    10021 tctggagggc aaaaacagcg tgtggcaatt gcgcgtgcct tggccaatga tccaaaaatc
    10081 ttgatttcag acgagtcaac ttctgccctt gatccgaaga caaccaagca gattttggcc
    10141 ttgttgcaag atttgaacca aaaattaggc ttgactgttg tcttgattac gcatgaaatg
    10201 cagattgtca aagacattgc caaccgtgtg gcggttatgc aggatgggca tttgattgaa
    10261 gagggtagtg tgcttgaaat cttctcagac cctaaacaac ctttgactca agactttatc
    10321 tcaacagcca caggtattga cgaagccatg gtcaaaatcg agaagcaaga aatcgtggaa
    10381 cacttgtctg aaaacagtct cttggtgcaa ctcaagtacg ctggatcttc aacagacgag
    10441 ccacttttga atgaattgta caagcattat caagtaatgg ctaatattct ctatgggaat
    10501 atcgaaatcc tcgatggtac tcctgttgga gaattggtgg tggtcttgtc aggtgaaaaa
    10561 gcagcgttgg caggtgccca agaagccatt cgtcaagcag gcgtacagtt aaaagtattg
    10621 aagggaggac agtaagatgg aatcattgat tcaaacctat ttgccaaatg tctataagat
    10681 gggttggtct ggtcaggcag gctggggaac agctatctac ctaaccctct atatgacagt
    10741 tctttccttc attatcggag gcttcttggg gctagtggca ggtctctttc tcgtcttgac
    10801 agcgccaggt ggtgtcttgg agaataaagt cgtattctgg attttagaca aaattacctc
    10861 aatttttcgt gcgattccct ttatcatcct cttggcaatc ttgtcaccac tttctcactt
    10921 gattgttaaa acaagtatcg ggccaaatgc agcccttgtc ccactttctt ttgcagtctt
    10981 tgccttcttt gcccgtcagg tgcaggttgt cttggctgaa ttggatggcg gtgtcattga
    11041 ggcggctcaa gcgagcggag cgactttctg ggacatcgtg ggtgtttacc tatcagaagg
    11101 tcttccagat ttgatccgtg tgacgactgt gaccttgatt tcccttgttg gggaaacagc
    11161 tatggccggt gcggttggag ctggtggtat cggtaacgta gccatcgctt atggatttaa
    11221 ccgctacaat cacgatgtga ccatcttggc aaccattatt atcattttga ttatctttgc
    11281 aatccaattc ttgggagatt tcttgactaa gaaattgagt cataaataaa aagagccgcg
    11341 tggctctttt taactgatca gattttctgt gcaaattttt tactcaaggc ttgtccaatc
    11401 aaggcaccca ctagggctcc gatgacaata cttgcgataa atagaaggac agttccaggg
    11461 tttggagcga ccatgatacg gtcgatatat tcttgggatt ttcctcttgc cagaagagta
    11521 gccatatagg ctttgggcgc aatccacata agcaagattg gtcctgttgt actaaaggcg
    11581 aaaataatga aagaaaggaa gttctttgtt ttgtccttgt attttcctaa atgagctact
    11641 tcatctgcta ggaggccaca gataattcca ggaaggaagg aaccagcacc gtgtttagtt
    11701 cccaagaaaa agagggcaat gacaaggccg atagtggtaa tggctccaaa gcgcggaact
    11761 tttgcgacta ggatcatata gacgctaccg ccgacaaggg cagtaaaggc aggcgcataa
    11821 aacatgtttc cagtttggtc aaagagattg cccaaaagga caccaatccc catgcagagg
    11881 aagtaaagaa ctgcaaaaag cagtgtagtt aagatagatt tcttcatgaa ttgtctcctg
    11941 ataatttttt cacaattctc attgtaccac ggtttggtgg gattgtaaat ggatactaga
    12001 agtttttgaa aacgcttgaa atatgatata atggtttcat agttattttt aggggaatat
    12061 catgggtaga tttttagact ttgtctttaa tcgtttcttt ttagggatga ttgcgacagc
    12121 cttcttttgg ctattaactt tagcaggagg gattatcctt ggtctagcgc cggctagtgc
    12181 caccttgatg agcttatatg cagaacatgg ttatagcttt cgggaataca gtttgaagga
    12241 ggcttggtct ctttacaagc aaaattttgt ctcaagcaac ctgattttct atagcttttt
    12301 aggtgtgggt ctagttttga cctatggttt gtatctcttg gtgcaattgc ctcatcagac
    12361 cattgttcat ttgattgcga cccttttgaa tgtcctagta gttgccctga tctttttggc
    12421 ttatacagta tctttaaaat tacaagttta ttttgccttg tcctatcgaa atagtctcaa
    12481 attatccttg attggcatct ttatgagtct agcagctgtg gccaagattc tccttgggac
    12541 tgtgctactt gtagcaattg gttattatat gcctgccctg ctattttttg taggaattgg
    12601 gatgtggcat ttctttatca gtgatatgtt ggaacctgtc tatgaaatca tccatgaaaa
    12661 attggcgaca aaatagaatg aagcagtttt ggctacatac gcttctaaga acctatagtt
    12721 cagtgatgat cattatcatt gcgagttttg caatcttact ctcttacgct gactgggatt
    12781 cacgtgaaaa ggaagcccag agagtagccc agcgtgtaac tgctagaaca gtgagtgaaa
    12841 ttgaatatta ccatagagag tcaacccaga tagctcaggc tttagttgaa aaccaagctc
    12901 gtattgaggg aatctataaa tactttagtc ttagcatgcc agactatttt tactggcaat
    12961 tagagcggaa agcttcgcct tatatatcag tctctctgta tgaaaatgtt gatgacctct
    13021 atgttcgaaa tgattttgta actggagtgg ccattgcttt tcaagattac aaggaagtct
    13081 atgtttctac taaagacaaa cgtagtggag aaaaaatcag ggctgaggat ttcaaaccag
    13141 caggaaatag ttttgccatt ccggtgtcag atccagtgtc agatcaagat ttaggagtga
    13201 tttacatctc cttggatcct gctgttttat accatgccat tgataatact agaggtcata
    13261 ctccgatggc agtaacagtg acctcacctt ttgatacgga gatttttcat attggtgaga
    13321 cagttgataa ggagagtgaa aattggctag ttggcttaac ttctcatgga tatcaggttc
    13381 aggtggcagt tcctaaaaac tttgttttac aaggaacagt gactagctct gctttgattg
    13441 tgggtttgag ccttctcttt attgtcattc tttatctgac tttgaggcag acttttgcta
    13501 attaccaaaa gcaggtagtg gatttagtag aatccattca agtcattgct caaggcgaag
    13561 aggggcgtcg gattgacatt tccgagaaag atcaggaatt actcctaatc gcggagacga
    13621 ccaatgatat gttggatcga ttggaaaaga atatccatga tatttaccag ttagagctta
    13681 gtcaaaaaga tgccaatatg cgagccttgc aggcgcaaat caatcctcat tttatgtata
    13741 atacgctgga gttcttgcgc atgtatgcag ttatgcagag tcaagatgag ttggcagata
    13801 tcatttatga attcagtagt ctcttgcgta acaatatttc cgacgaaaga gagaccctcc
    13861 tcaaacagga attagaattt tgccgtaaat acagctatct ctgcatggtt cgctatccca
    13921 agtccattgc ctatggtttc aagatagatc cagagttaga gaatatgaag attcccaagt
    13981 ttaccttgca accgctggta gaaaactatt tcgcgcatgg tgttgaccac aggcggacag
    14041 ataatgtgat tagcatcaag gctcttaaac aggatggttt tgtggaaatt ttggtggtcg
    14101 ataatggtag aggaatgtcg gctgaaaagt tggcaaatat ccgagaaaaa ttaagtcaga
    14161 gatattttga acaccaagcc agctacagtg atcaaaggca gtctatcggg attgtcaatg
    14221 tacacgagcg ttttgtgctc tattttggag accgctatgc cattactata gagtctgcag
    14281 agcaagccgg tgttcagtat cgtattacaa ttcaagatga gtagaaaggg agaaaatgta
    14341 taaagtatta ttagtagatg atgagtacat ggtgacagaa ggtctgaagc gtttgattcc
    14401 ctttgataag tgggatatgg aggttgtcgc aacagccagt catgccgatg aagctctaga
    14461 atatgttcag gaaaatcctg tcgatgtcat catttccgat gtcaatatgc cagacaaaac
    14521 agggcttgat atgattcggg agatgaaaga gatcttacca gatgctgcct atatcctgct
    14581 ctcaggttat caggagtttg attatgtaaa aagagcaatg aaccttagtg tggtggacta
    14641 tttggtcaag cctgttgata aggtagagct gggaaatctg ctggagaaga ttgcaggtca
    14701 gctcggcgag agagggaaga aaagtcagac tcttagtcaa gaattagacg aggctggatt
    14761 tgttagttat ttaggggata aggagaattg gtggataggt ctatccaagg aaaaacaagg
    14821 ttccttcacc attccctact atgtcttggg tcaagactgg cagattttca tttctggcca
    14881 acccttagat ggcttagtcg ttactccctt tgaagctccc tatcaagaac actttgaacg
    14941 ctggaagctg aatgctgaga aaaccctctt ttacggttct gtaaatctgc agcagtctga
    15001 gagtctcttt gcctattacg aaccgattta tagggttatc attcagggaa atctcaatca
    15061 aatcgtagaa gagttaaatc tcttggagaa ggtagttctt gaaaatacgc cgcgtgttcc
    15121 gattactaaa cagcttttta ttcagtttgt catggatgtt ttccatttat ttgaacatct
    15181 caaagctgat gacctgacag acatcgttaa aaccattcat gctattcaat ccttcgatga
    15241 attggttcct tatatcaagg aaactctgac cagctttttc ggtcaatacc gtatgaatga
    15301 aaatgtggtc agtgtgctgg aagtcattgg tcgtgattac caaaaagagc tttccctcaa
    15361 ggatatcagt aaggctctct ttatcaatcc tgtctatcta gggcagttga ttaagcgtga
    15421 aaccgattcg acttttgcag agttactaaa caaacaacgt attaaggctg cccagcagct
    15481 cttgctttca actagtgaca gcatcgaaga tatttgttat gctgttggtt acagtaacct
    15541 tggatatttc tataaagttt tccgaaaatt gtgcggaaaa tcgccaaaag cctaccgaaa
    15601 acaggtagaa actatactat aagatttgta ttcctttaca aaatgtgcta taatattatc
    15661 aggaggttct atcatgaaaa agaaaccaat ttatctatgg gtcttgctaa tcttgtctgc
    15721 ccttatttca gttccgtctc tgtttggaat tgtgagtccc ttgcctagta aagaagccct
    15781 tcgtgctgct cagaaacaag ttgcaggggt caatgctcag caattagaag accagcttaa
    15841 ttatacctat agagtagcag aagcatctca ttctattttt aatgttgctt tgattgtgct
    15901 atctactatt ttagtggtcg tagcgattgt cttccttgtt cgtaaaaatt tgcaatatgc
    15961 aaactatact tacgttggct atgttttgtt agctattatt ggttcgattt atggctatgt
    16021 tggtttacaa gatgctgtgc agttggttca agatgagagc atgcgtttga cagtgagtat
    16081 tggttcaaaa gctgttagca ttttctatat cgtcatcaat gttctcttcc tagcccttgt
    16141 cttctataag atgtggcgac aacagaaagc cttggcagaa gaagaggaaa cagaagagct
    16201 tgcctaagta ttgacaaaaa agaactatca agatacaatc ttggtagttg ttttttgatt
    16261 atagataaaa tcatggaggt acatatgaag acaatttctt tagtttatat tagtttgagt
    16321 ggcaacactg aaagttttgt gacgcgcttg aaagactatc tcttgtccca gtacaaaggg
    16381 attgaggttc aaaagattca tatcaaggat ttggtcaagg aaggcaaaaa tttctacgaa
    16441 atggaccatc cctatgttgc ttttttgccg acctatctcg aaggtgggaa tggcgtggat
    16501 aacggagatg ttgagatttt gacgacaccg gtgggagatt ttattgccta tggtaacaat
    16561 gctagtaagt gttttggtgt ggttgggtca ggaaatcgta actttaataa ccaatactgc
    16621 ctaacagcca agcaatacag tcaacgcttt ggctttcctg tattggctga ctttgaaatg
    16681 cgaggcatgc tggaagatat caaacatgtc gcagctatta tcgcagattt gtatgagttg
    16741 gaaaaggaga attaatactc aatgaaaatc aaagagcaaa ctaggaagct agtcgcaggt
    16801 tgctcaaagc acagctttga ggttgcagat agagctgacg tggtttgaag agattctcga
    16861 atagtataaa gttcttataa gaggtggttg aagttgttca actgtttttt gagtataaac
    16921 agtctttaag aacgtaaaaa agcataagtt caggtcttca aaaccttgtt cttatgcttt
    16981 ttatcataga aatatttgct gaattttctc ttgaaatgaa accttatctt catctcgcgc
    17041 ttgtccctta ccctgctttt ccgattgcga gtgcgtagat aaagaagatg gcgaagccaa
    17101 agaggaaaat caatcccgca atggcaaggt gtttgagcca agaaggaaga tttttgtttt
    17161 cacgtgttac caaggcgtaa ttcaaaagag caaagaaagg tgttgtcagg aaagagccaa
    17221 tcatggcaaa gcggagcatg gttgaaacct gaccagcgaa gaacttgata atgatgatac
    17281 cgatgatagc agtgatggtc atccagatgt tcaaagattt acgattatcc tctttttgac
    17341 tgattagcag tcggagagat tcctgattaa cgcgagaata gccatcgata acagttataa
    17401 ctgttccaaa gatacagagg aaggcaataa aggtaatcaa gtaacgggac cattcgccaa
    17461 gaacagaggc atacatgccc acgaattgag agatgtattt ggctgaagca gcttcaaccg
    17521 cctgccctgt aggatactga atcagtgctc ccagtgccac aaagaagacg gctaggatag
    17581 ctgttccaat ataaccagtg ttaaagtcaa acagagcgtc ttctgtgtta aagttgacgg
    17641 tctttctctt ttcagctgac caaagtgaat tgatggctga aatttcaata ggagccggca
    17701 tccatcctag gagggagacg atgaagggca gagctgccat ttgccaaggt gtcttctcga
    17761 caaaatcaga actgtattct ggatgcttga ccgccgcaat gataactgca agaacagtcg
    17821 caatggttaa ggcagacata atccatttga ccatgccgtc taaaagtttg tagcctccaa
    17881 agagtagcat agcccaaatg attgcaacga gaatgaggga ccactgagta atgctaagtc
    17941 caatcattgg gaaggcactg gcgatgatag ctgagcacag aatggcaaca ccagccgtgt
    18001 tgaccatagc cgaaaagaca ttgaggataa agaaaatcca gagatagagt tttccttttt
    18061 cggcataacc ttcaaccaaa gtctttccag tatcagctgt gtattcagca ccaaaacgga
    18121 aaaatggata tttaaagaca ttggctaaga tgaccaagag aagtagagac caaccgtaag
    18181 aaccgccagc ttgagttgag gatacaatgt gggaacctcc aacagcggca gttgccatta
    18241 ggattccagg tcccattgct tttagcttgc ttgcccaggt tgattgattt aaggaaatag
    18301 cttgcgacat gataaatact cctttttgaa ttttcagaat aatctgtata tgtaatctat
    18361 attctacaaa aaattttgga aaaatgcaag agtattttga aaaaagatag aaaatttaca
    18421 aagaaaatct gaaataactg ttatgatata gaggattgaa actagaatag tacacctctg
    18481 cttctaaaac attgttagaa atcgatttga ctgtcctgat cgatttatcc tgttcttatt
    18541 tcatttcact atagtaaggt gcagcaggat aaagaaaaac cgagaagttt ctttctcgga
    18601 tttgcttatt atgaggttcc tattttctat gctccaagag ttgattgatg tgatctactt
    18661 ttttagcctc tcttttatag agaatagccc agatgatgag atagacaatc gcaaactcga
    18721 taatgagctg gaggtagaaa atccagtgga aagggaacca accagcaaga gttgctagtg
    18781 ggacaaagcc agccagcata aggaagaaat gagtcagagt ggcacgaagc atgctccagt
    18841 cacggctaaa taagcggttg ccaaagttga agagcatacc gatggttgcc cagataagtg
    18901 tgcagtagag caagaccagg gcaccgtgaa cctgatgctg atccatcact tggccgatga
    18961 gagagtaggg atttagtggt gcgtaggtat ttggtgcata aatgagtgaa aagaggatag
    19021 agaggatgag gccgataaga acaccggtag ctgcatcgtg aaatacttgt tttttcatag
    19081 ttctaatttc tccttgatgg tttttagata acggcgtgaa gagtaggtga agctttcgtt
    19141 tttcaagaaa atttctacca gaccgtttgg cgtgagcttg aggtgagaga tggaatcgat
    19201 attgatgatt tctgattggg aaatttggat aaaattggtt ggcaagagtt taagaacctg
    19261 atagagtcgc aaatcaatgc tgtaggtctg actcgcggtt tctgctagaa ccttccgatt
    19321 ctcgatatag aagcgctgaa tcttgccaat ctcaactaga tagacctgat catcgatttt
    19381 tcctttgatt ttttctcttt ggtccagatt ttctgcgaac tcgatgactt tctggacttt
    19441 ttcggtttct tgaggtgctt ggacaatcag cttttcctcc tcgtaagtct cactaatctg
    19501 tagttctact ttcatagttt tctctccttt tcagttatac aaggttgtga tcacttcctg
    19561 tatatcctta ttaaacacta ttttatagcc catggcaagg aaccttgtct atgtggaggg
    19621 attgggctcc tatgtggtgg agcttttctg ttctttctga aatatggtat aatagcacta
    19681 atcaatttct aggaaaatag atacggaaag gggctgaaag aactagggga acagttggaa
    19741 ttagaaagtg ataggtatga aaagtggcgt tgaagctgaa taagtttata aagcgtttga
    19801 atgaagaaat ggaaagtaaa taagttgacg atgaattaca aaatagattt tatctacaat
    19861 ttgtatcttt caaatcattg atttgaattt tagatttaat catgttacaa ttaaaactga
    19921 aatcaaatag aagaggaaaa tgcaaacgtg ggcacactat tagcaacaag attaaaaaat
    19981 agacggaaag aattaaaaat gtctcagcga gaactagctg aaggtatctg taaacagggg
    20041 caaatcagtc gattagagag cggagagttt acccctggag cggatttcct gaatgccctt
    20101 gctaagaagt taaaagtcag tatggattat ttttttgatg agcaggttgt agagaaagtt
    20161 gaggagttat cagaatttaa gaaattagca cagacattta ttacaaatcg caattatgag
    20221 tctttgaaat atatatatga attggagaat gtaaaagctc accgcctatc tttagcagat
    20281 aaaatctaca tggaatggat aaaatctctg atagattttt atttttacgg acagaaagaa
    20341 gatgcgattg tacgattaga gggggtatta tcacagttaa gtgtatctga tttgaactat
    20401 ctccaagttt caaacaccct attcaatttt tattatgata ttggagattt aggtcgtttc
    20461 aataaaattc gtgaaaaact agagtatcaa gtaaatcacc tcaatttgag tacaatcgaa
    20521 gagttagaac tatctattaa gtttaactac aacgtttgtc gttatctatg gttacagaaa
    20581 aatattgaag aagctattac taaaattaca gctactataa aacaatgtaa ggcttacaga
    20641 acgaattatc ttttggctga tttgtactta ttgatgggaa atgtaagtga aaatttttct
    20701 tctaaaagtt cggtgaaaga atattttgag acggcatatt ttctatacaa acttgaggag
    20761 aacatgtcaa tgactctgaa agttgagcat tacattgcag atataacaga ataatgaata
    20821 cggtgttcaa gtgagcatcg tttttcaaac ctagttcaga tacaaaaaag tatcaaacaa
    20881 aaaaaaataa aaaaacatta taaaaacaat tgacaagcta attttgaagt gataaaataa
    20941 atgcaagaaa acaaaaggag aggtatatga gaagtttgtt taagaaaata gttgctgtat
    21001 tagttattgg cttaattctg ttaggaattg cgagaacacc tcaagttcat aagatggcta
    21061 gagggattga tcctggtcct gcgaatttta tttagaaatc aatttctact aattgagtac
    21121 taattgagta ttaatgggta aaaagattgt atggataaga aaaatttact tgtattggtt
    21181 actggttcgg taggtgccag taatgtagat acatacttat attatataaa aaaattctat
    21241 aatgttaaag tgatactttc tgaaaattct aaaaaattta taagtaagga attaattagt
    21301 tatttttgtg ataaagttta tgatgaaata tttgttgaag aggtagttcc gcacgttttt
    21361 ctgccatatg aatctgactt acttcttatt ttaccagcta cggcaaatgt gattggcaaa
    21421 attgctaatg gtattgctga tgatttagtt acagcaactg ttttaaactt taataaaaaa
    21481 ataatttttt gtcccaatat gaactctact atgtgggaca atcacatagt tcaaagaaat
    21541 gtatcaattc taaaggagtt gggacatata tttttatttg agtctaaaaa aacatatgag
    21601 gtaggattgc gtaaagcaat agattcaaca tgttcaatgt tacaaccaca gtcgttagta
    21661 aaagaactta tcaaattaga aaatattgtc cttgaagagg gacattaaaa actactgaga
    21721 atattaagga ggggaaaaaa tggaaaattc atcaatcgat gtagatatgc tgttggaaga
    21781 attgacacaa gaagcaatgg tcgttgttgc tgttgataag gactgttaat ttaaacttat
    21841 ggcaatatat gaaaggttac tggatgtttt aaattatgca ggcagtagcc ttttattata
    21901 tacaaatgga taaagtaagg ataatacaat gattaataaa aaaatacaac aagttgtttt
    21961 ggaatcatta cagaattttt tgaatgggaa cttcatttcg ccttgtgtag tctatgattt
    22021 tggcttgctg gaaactgtac ttgatgaatt taaaaatcaa attcctgtaa cattcaatta
    22081 ccaacttttt tatgccgtta aagcaaattc aaatgagaag atacttgaat tcttagtaga
    22141 taaaattgat ggagttgatg tggcgtcatt atctgaatta gatgtggcta aaaaattttt
    22201 cccaccaact caaatttctg ttaatggtcc cgcattt
//
LOCUS       DAVKEV010000037        21540 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVKEV010000037 DAVKEV010000000
VERSION     DAVKEV010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21540
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.037"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(505..2232)
                     /gene="ezrA"
                     /locus_tag="VWZ68_001552"
     CDS             complement(505..2232)
                     /gene="ezrA"
                     /locus_tag="VWZ68_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEU9372559.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPPQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2314..4260)
                     /gene="gyrB"
                     /locus_tag="VWZ68_001553"
     CDS             complement(2314..4260)
                     /gene="gyrB"
                     /locus_tag="VWZ68_001553"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEU9372560.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVYVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4275..4838)
                     /locus_tag="VWZ68_001554"
     CDS             complement(4275..4838)
                     /locus_tag="VWZ68_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU9372561.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4923..5477)
                     /locus_tag="VWZ68_001555"
     CDS             complement(4923..5477)
                     /locus_tag="VWZ68_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEU9372562.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(5488..6711)
                     /locus_tag="VWZ68_001556"
     CDS             complement(5488..6711)
                     /locus_tag="VWZ68_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU9372563.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6748..9198)
                     /locus_tag="VWZ68_001557"
     CDS             complement(6748..9198)
                     /locus_tag="VWZ68_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEU9372564.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVVLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9398..10327)
                     /locus_tag="VWZ68_001558"
     CDS             complement(9398..10327)
                     /locus_tag="VWZ68_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU9372565.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10467..10754
                     /locus_tag="VWZ68_001559"
     CDS             10467..10754
                     /locus_tag="VWZ68_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEU9372566.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10788..12122)
                     /gene="ciaH"
                     /locus_tag="VWZ68_001560"
     CDS             complement(10788..12122)
                     /gene="ciaH"
                     /locus_tag="VWZ68_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEU9372567.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12112..12786)
                     /gene="ciaR"
                     /locus_tag="VWZ68_001561"
     CDS             complement(12112..12786)
                     /gene="ciaR"
                     /locus_tag="VWZ68_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEU9372568.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12895..15441)
                     /locus_tag="VWZ68_001562"
     CDS             complement(12895..15441)
                     /locus_tag="VWZ68_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEU9372569.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15564..16004)
                     /locus_tag="VWZ68_001563"
     CDS             complement(15564..16004)
                     /locus_tag="VWZ68_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEU9372570.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQAHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15979..16848)
                     /locus_tag="VWZ68_001564"
     CDS             complement(15979..16848)
                     /locus_tag="VWZ68_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEU9372571.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPSVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16890..17618)
                     /locus_tag="VWZ68_001565"
     CDS             complement(16890..17618)
                     /locus_tag="VWZ68_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9372572.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17626..18105)
                     /locus_tag="VWZ68_001566"
     CDS             complement(17626..18105)
                     /locus_tag="VWZ68_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9372573.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVIALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGLPELDKTSYMNWKVK"
     gene            complement(18116..18814)
                     /locus_tag="VWZ68_001567"
     CDS             complement(18116..18814)
                     /locus_tag="VWZ68_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEU9372574.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     RFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFETGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18807..19073)
                     /locus_tag="VWZ68_001568"
     CDS             complement(18807..19073)
                     /locus_tag="VWZ68_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEU9372575.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(19139..20065)
                     /locus_tag="VWZ68_001569"
     CDS             complement(19139..20065)
                     /locus_tag="VWZ68_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEU9372576.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20140..20955)
                     /locus_tag="VWZ68_001570"
     CDS             complement(20140..20955)
                     /locus_tag="VWZ68_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372577.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20959..21279)
                     /locus_tag="VWZ68_001571"
     CDS             complement(20959..21279)
                     /locus_tag="VWZ68_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU9372578.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(21369..>21540)
                     /locus_tag="VWZ68_001572"
     CDS             complement(21369..>21540)
                     /locus_tag="VWZ68_001572"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372579.1"
                     /translation="DETDEVSSKHCFEVVDETDEVSSKHVFEVVDETDEVSNHTYGRA
                     TLTWFEEIFEEY"
BASE COUNT         6524 a         4721 c         3767 g         6528 t
ORIGIN      
        1 tctagtataa atagcgagaa atatctatcc tatcttctag aatgtcttcc aaacgagaaa
       61 actctcgtaa acaaaaatgt tttagaggcc tatttaccgt ggactaaagt tgtacaagaa
      121 aaatgcaaat aagaaatctc cagattagga actatccgtg agttctctag tctggagatt
      181 tttcaataga cttcgttatt ggacggttac caagttactc aaagtacaga tttgaagctg
      241 cagataagac tgacgaaatc actttaatac taaatgaaaa tcaaaaagca aactaagaag
      301 ctagcctcag gctgtacttg agtacggtaa ggcgacgctg acgtgatttg aagagatttt
      361 cgaagagtat aaaacactgt tttgaggtgg tggataaatc ggctgggtaa aaactcaatc
      421 tcaggagaaa atgaagtaaa tctccccaca actatagaaa aagatttgat tctgctcctc
      481 acacaataaa atctttttct tttattaaaa acgaatcgtt tcacgtgttt tctcatatga
      541 ggtaacaaag cgattggtta caccaggctc tgccacttcc aatgcttgag aaatcttatc
      601 aaatgaagcg tgataatcaa attctttttc aaaaatatct aaagcttcgt taaatgcttc
      661 ttgaatgcgt tcatcaaatg agcgatagcg gttagaatat tgcaagagtt gctctgtcaa
      721 agttgcatat tgtacaatat tataagtttc cgtttctaaa gcttccatat cattcgttgc
      781 aatttcaaga actcgggtaa cagattcaat gttaatcatt ttttgttcta actcaaccat
      841 taaatcctcg gtattattgc ttgccgtaaa gaataacttc aagaaagttt gtggaatacc
      901 tggcagattg cgtttttcca tgtatcgctt gatagtatgg agacgattga cataaacatt
      961 ggccttttga cgtgcattaa tatcatcttt ctcaatttgt gtcaggcgct cactaactga
     1021 aatttgctca tcttcaatat cttttagttg agtttgtaaa tcctcaagat tttcttcaag
     1081 aactgaataa gcttggggtg gttcttcttg atttgaagtt acctcaacaa tagctgcctc
     1141 aaaactctct aattctgtct gaatacgacg aacatggctt gcagctgtct caggaagtaa
     1201 ataggtcttg ttcaaacgtg caatatcttc tcccaataaa gtattattct ctttcatatg
     1261 ttgaagataa gttggaagag ttgcaagtag attttccact actttctgag cagcaatttc
     1321 tcgagtaaaa atatcataca aggcattgat ttcctcttgt gcctgtccat tctcatattc
     1381 ggcattatcc aattccaact gacgaatatt ctcttggttt ttcttgaatg cttcataaag
     1441 caagtggaaa cgcgcttcaa tatccgtttc aacaaaatga taattagcat caattagttt
     1501 acgataaccg gcttccaaat cctgtaattg atctggcaat tctgtagaaa gcgtcgtaac
     1561 caaggctgga acacgatcca caatatgact taaggccaaa atgtgatttt ctgtattatc
     1621 caaaatcact gcggcttcca cagggtcacc cgatgaattc aaggttacaa attgtgaaaa
     1681 ttcagattgg atattttcta attgtttttc aatttcatcc aaggcttgac catactgttc
     1741 tgaattttca gcaactctat gctgaagttc ctcaaataaa tccaaagcat gaagaacacg
     1801 accactattt ttagattctt gcttctctaa gtctgccaaa gcattgcgaa ttgccgcaat
     1861 atcttcttca atcaaagtaa tttgactctc aatttggtca atttgatgac tggccttgag
     1921 aaaacgaaat gaatggttat aaccttctgc ttcaaagaga ttattttcaa tatcggcaaa
     1981 agagttgaga gataaatcga cccatttttg attccattca cggaaagcca cttgactttg
     2041 tccaatcaag tgcatatttt ttacagcttc tacttcatca tttactggaa gattgtatag
     2101 ttcttctttt ctttcttcta gtgcctctaa tctcccctcg tttcgcttac gtagaaagat
     2161 tgccactaca taagccagaa ctaaaatgac tgcaattgca accattaaat aaattagttg
     2221 tccattagac atatcaaact ccttttttac ttgaaacaat cgtaacgatt atatcatatt
     2281 ttttagacca agggaactac ttctccctat tttttagaca tcaagtgtac tatagacagc
     2341 attttcttcg ataaactcac gacgaggctc tactcgatcc cccatcaaca tatcaaagat
     2401 tttatctgct tctgcagcat catctacaga aactctagcc atcaagcgat gttcgggatc
     2461 catggttgtt tcccacagct gatgatcgtc catttcacct agccccttat aacgctgaat
     2521 agtcggtttg gtacgacctt cactataacg ggctaaagct tcttggagtt tgatttcttg
     2581 atctgcaccc ggctggatat attctttaat ctcgcttcca accttgacac catagattgg
     2641 tggttgggca atataaacat aaccagcttc taggattggt ttcatataac gataaatcaa
     2701 ggttaaaaga agggtacgaa tatgggctcc atcgacatcg gcatcggtca tcaaaacgag
     2761 tttttggtaa cgggctttcg aaacatcaaa ttctgcgcca aatcctgttc ccatggctgt
     2821 gaaaagacta cgaatttctt cgttagctag aatcttatcc atacttgctt tttcaacgtt
     2881 caaaatctta ccgcgaattg gaaggatagc ctgaaactca cggttacgac cagatttggc
     2941 tgatccacca gctgagtctc cttcgacgat gaagagttct gtttcagcag ggttattaga
     3001 agaacagtct gctagtttcc ctggaaggtt ggaaatttcc aaaccagatt ttttacgtgt
     3061 gacttcacgc gcacgcttgg cagccacacg agccttggca gctaaaatcc ctttttccac
     3121 gatacgtttg gcaatctgtg gattttccat gaggaaatcg gagaaggctt cactgaagag
     3181 gcgattggta atcttgacca cttcgctatt tcccaatttg gtcttggttt gtccttcaaa
     3241 ctgtggattt gggtgtttaa ctgagataac tgcagttaat ccttcgcgaa catcttcccc
     3301 tgttaaatta tcttcattgt ctttcagtaa cttattctta cgagcataat cattgataac
     3361 acgagtcagt gccgtacgga aaccttgttc atgcgttcca ccttcatggg tatgaatatt
     3421 attggcgaaa ctcatgacat tttcatggta acctgttgtg tactgcatgg ctacttcaac
     3481 tgtaatatca tccatctcac cgtctgtata gattggtgta tcaaagatta catccttgtt
     3541 ctcgttgata tattcaacgt aactagcaat cccaccttca taatgataat gcttggtttg
     3601 ttccaaacct tggcgcttat cagtgatgga aatttgaaga ccgcgattta gaaaggccaa
     3661 ctcttgaatc cgtttattta atttatcaaa atcaaagatt gttgtttcag tgaaaatttc
     3721 tgggtccggt gtgaagtgaa ccgttgttcc agttctatct gtatccccaa ccacctcaag
     3781 gtctgcaaca acatgaccac gacggtattc ttggtaatga atcttaccgt ttttatggac
     3841 ataaacgtct aattgagtgg aaagggcatt aactactgac gaccccaccc cgtgaagacc
     3901 acctgaaacc ttgtatccac caccgccgaa ctttcctcca gcatgaagga ctgtaaagac
     3961 ggtctcaaca gcaggacggc ctgttttttc ctgaatatcg actgggatac cacgcccatc
     4021 atccacaaca gtaatcgaat catctggctc aataaaaact tgaatatggc tggcaaatcc
     4081 tgccaaggcc tcgtcaattg agttatcaac aatttcccag actagatggt gaagaccttc
     4141 ttttgaggtt gatccaatgt acatccctgg acgcatacga acagcctcta agccctctaa
     4201 aacttgaatt tgactggcat cataatcctg tgcctgcaga tttttgattt cttctgtcat
     4261 cttattcctt tttcttatat gtctaatact tgtcttaaat tcacgatact ggtaaacaag
     4321 tgggtatcaa gtcctgcagc ttgacctgct tcgatatcaa tcggccgatc accaatgaca
     4381 agaccagagc taatctgata cttttctctt aaataaagca tggattcggg atttggcttt
     4441 ctcttaaagc ctgagctaga agtcaccact tctgtaaaat aagctgctat agaggttttt
     4501 tctaaaattt ccaaaacctg atcatttcga tgagagacca aaaaatgacg gccaccttga
     4561 tttgaaatga cttccaatag gtcagaaact ccttcaaata aaatcgggtg ttcaagctct
     4621 ctggcttcat tttccttgta cttttctaaa aaattctcta aattgggagc gaatgtctca
     4681 atcgcaaaag gagtagaaac ctttaaagct tgatagacac tgtcatggtc ttgtgtgata
     4741 ccatacagtg ccaatgtttc aacaaatgca gctgttgaag tttcataatt atccagtaaa
     4801 gttccaccta aatcccagat gtaatcgtga tatttcatgc cctttattat agcatttttt
     4861 tatgaaaaaa gcgatgattt ccctgagttt tccacataaa aaacgagaga ataactcccg
     4921 ttttactgat ttttaccaaa gacatcttga tagagcattc ctgttcgtaa actctctgcg
     4981 tcccctccta gttgctccac caactcgtag gcaaaggcaa gggctgttga aggaccccga
     5041 ctggttgtca actgaccatc taccactact gtttccttga cgtagtgacc atcaaggatt
     5101 tgctcttgaa cgccgtcata acaagtgtat cgcttatttt tcaatatctc tgcttgattg
     5161 agggcaattg gtgccgcaca aatggctgct agtttcttcc cttcttgctc gaagctttgc
     5221 aattcttgaa tcaaggtctg attatcacgt aaatgtgcag aaccaggcat acctccagga
     5281 agaacaatca tatcatagtc tgataaatct ccatcaaaga catgatctgc tcttacttgg
     5341 attgcatgcg aacccgttac ttgctcttca aaaccaacca tatcacatgt gatattggct
     5401 cgacgcaaga catctacaac tgtcaaggct tcaatttctt caaagccctg agctaacata
     5461 actgctactt ttaccatgat tttctcctta tttaatttgt tttaatacaa cctttttccg
     5521 tttgaatggg acttttccgc tcttttcttc agctaaatta gtctggtaac tcatcgataa
     5581 aagcaaacca acaccaatca aattactgat aatagctgat cccccttgcg aaatgaaagg
     5641 caagggaatc cccgtcaaag gaagtagtcc agtcacagca ccgatattct caaagatgtg
     5701 gaagagcaac atcataatca aacctgtgga aatataagtg tagaactggt tatttgattt
     5761 aagagtaatc ttcaacatac ggtaaatcaa catgagatag agggcaataa ccaggacaga
     5821 gccaataaag ccaaaatctt ctgcaataac cgtaaaaatc atatctgact ctcgaactgg
     5881 gataagcaga ttcgaagcat taaatccctg accaaataag ccaccactcc caatggcaat
     5941 ctgcccttga gcctgctggt aagtcgttgt ttgggcaaac tcaaagggat tgagccaagc
     6001 caaaatccga ttaatttggt aggtcggcat tccaatctgg tgaagaaaag ctcgtccgtc
     6061 cttgctaata aagatagcta agaaaccagc aactcctgtt acagcagtca caaatactgg
     6121 gataataatt ttccaagaaa cccctgataa taaaacgatt cctgagaaaa tggctacaaa
     6181 aaccaaagcc gtccccaagt cactttgaag tgctaaaaga actaggactg gaatggtaaa
     6241 gagaatcatc cagaaaatta acaaaaagtc cagcggaacc gtgcgtctcc attccttatg
     6301 tttctttgta aattggacaa tgacacgagc caacatgagg atataggata tcttcataaa
     6361 ttctgacggt tggaataggg taattccatt tattgatacc cagtttttgg cacccgttga
     6421 tgcaactaag cttggattat aaaatacaat cggcaagatc ataagtccca agcctaaaat
     6481 atatagaaag ggggtcacct tccaaagaaa ttctgtatta aagagcatga ccacaaaacc
     6541 aatcacaagc cccaaggcaa tccaggcgac ctgctgccct aaaatgggca gaatattatt
     6601 gggataatca tgactaacgg ctatatagat agccaccaca ccgatgacca gtagaaaaaa
     6661 tactggcaag agcaaactgt aatcgactct tgagtcgaga gaacgtttca tatatactaa
     6721 ccttatactt tcatacaata ctatttatca aagttcatta aaaaatctat caatagcctc
     6781 gtcaacttcg gatcgagaga tggttttaac agtcgcttct tctgctagag atgctactat
     6841 ttgtttgccg tatcgttttc cgacgattct cctatccaaa ataagagtta aggaacgttg
     6901 gtattcacgt ctcatacttc ttcccaaagc ctgttttaaa cgaataatgg ccattggcaa
     6961 ttgataatca taaaaggcat ttttcccttc ttgattcagt tcttgattaa tctttttcgt
     7021 caagggttct tgaggatttt ggaaaggaag cctcggtaca acttgaatca caaaaggatg
     7081 gcttgaaaaa tcaactccct cccagaaact tgctgcacca agcaagattt gttgttcacc
     7141 tttttcaaag cgtttcttta gctgatgaac atccccattt ttatactggg ccaagtggct
     7201 aactgtaagt aaatccgata ctgctagaag catgtcttta gcggtaaaga gaaccaaaat
     7261 cggttgctgg aaagcttgaa tttccactag taaagcagct acctctctgg catagacttc
     7321 taaggaggtt tctgttacca gagggaaatc tttgaccata accacttctt gttcctgttt
     7381 tccccgagat tcaatcttga caaatttggc ttcaggatag cctaaaaggt ctgccaaaga
     7441 aaccctctga ctaatctcaa gagtagccga tactcccaag acttggcaac tctcaggaag
     7501 taaagaggac agaagagtac ggcctgattt tgtagaagaa atctgaattt tcttttgact
     7561 cgtttcagtt acttcaagcc agtaatcacc ttcagctgta aaatagcgaa ccagctcatc
     7621 aaagccttct acttctaatt ctgaaaaata ctgatggaga ttgtccagag aatctaagat
     7681 atttttccta gatttaccag actgaaattg ttctatcaag tagagacact caaagcgaat
     7741 actttctagt atccgttgtt gaaccctgtt ttcttctcct actaaagcct tatcaattaa
     7801 atcgataata gattgtatat cgtaggtctc ttgaagcaga ttttctagag ctaacaaaat
     7861 cttttggact tcatcaataa tcagtaaacg gtcactgaca aattcaggat tatcttcaag
     7921 tctggtcacg agataggcat gattagtcac taaaagcttg caagtctctg ccctttcttg
     7981 actacgtttc caaaaatctt ccgtcacaaa taagctctgg gatgataaat tcccatcatg
     8041 acgaaggtct gctagaaaat gttggtaacg gtagagttgc ccgatttcat ccaaatctcc
     8101 tgtctctgtc tcagtaagcc agaccaagac ttgcatttta aagcgtctaa ataagcgatt
     8161 ttcatcattt tcctgcaagg aatgataaaa ggcatccaac ttcagataat tttgtggtcc
     8221 ctttaagcta tgaatatctg tatggaacac ttccttgaga cgtttacctt cttcttccat
     8281 gatttgattt tgaagaatct ttgtcggaac actaagaaca atttgtcgct ctttggattg
     8341 agataaagcg ggtaagagat agccataggt tttcccaatc cctgtcggcg cttgaatcag
     8401 agagacaggt tcatctttca atagcaagac aacctcttta gcaaaacttt cttgttcctc
     8461 cctcacttca aggttcaaca gagaaatatt tttagaaaag tcttgagata gttttcgtag
     8521 ctccagagaa gctgccgttt tcttaaaata cagaccttga acttggacca agtctggaga
     8581 actcaggata gattggttgc gataagtttc ctcaataacc aggtaggact catataggag
     8641 agcgtcagcc atttccagca agcgttccaa gagaccttta ggaagctggg tcatcttttc
     8701 ccgtaaaaaa agaagtaatt ctgctgtagc ttgggcatct gaaagggctg tgtgtgcgtg
     8761 tttaagagga attcctaatt ctcgacacaa aatcggcaag ctatattttt ccagttcagg
     8821 gaaaaagacc tgggccaatt cgaccgtatc aacacgaggg tttcttagct catagccttc
     8881 aaaaaataaa ttttccgcca agagattagc atcaaactga acattatggg ctacaaaaat
     8941 cccatcctcc accaagtcaa atatttttct ggcaacttgc gaaaaatcag gtgcttgcgc
     9001 cagacgttgg tctgtcaatc ctgtcagttc tttgatatga gcatccaagg gttcatgtgg
     9061 attgacatcc gtcgtatagt gatcgacgat ttctccgtcc tcaatcacga caattcccac
     9121 ttggataatt ttagccttac tacctgtgct agttgcctct aaatccacca caacatagcg
     9181 attaccaatc gttttcatta taaaaaatta taccaaaaaa agggctattt ggcacctgca
     9241 aacataggat aattttcaaa ctcaagaaca ctacttttct taaaaatccc atcgaataga
     9301 gcattctagc ctgctgattt ttgtaaaata gtgaagaaat acgaaaaatt gagagaagaa
     9361 atgttttcat cttccttctc tcaacgaatc atgtatttta tttaaccatg tcaggatcgt
     9421 agtcataaaa tcctgtatca aggaaacggt ttttagggtg aagtttacga acttcttcat
     9481 ccagcaagaa ggcttgatca tggctaaagt tgccctcttg aatcaagtta cgcgcttgga
     9541 taaagagttt tgcaatctca acaaagttct gaccaggagt gtagagccct tctagtttcc
     9601 agcgagtaaa gccatgctcc accaattctg ttaatttgat catcaaatca aggtcattgt
     9661 tggcaaagat atgggtccca tgattatctt caaaaatgga atagtggctc tctggatcac
     9721 ttggctcagc caagaagagg tcacgtttat gcgtcttttc atcatcgata tgtgtaaagt
     9781 tatagtagtt ttgcaagagt ggacgtttag aatgatggat gacgctagca ccgtaaacca
     9841 aaacttcagc aggaatttcc aaaatctctg gcattttgaa aagttcagct gatggaattt
     9901 cacgcgccaa aacagcctca gatgcaccag ccttttgtcc ccagaagtta atctgacgac
     9961 tgctagttac catggttgaa gcatcgtaga tggtcttaaa tgaataacca tcgcggttaa
    10021 ctacgtaaaa gacgcctgca tccccaatcg taatatagtc tgtcttgatt tcttccaaga
    10081 agtctaagaa aggcttgata cggtccatca tatcttggtg catgagagca ttgaccgcaa
    10141 cgagcaattc cttaccagca tcatgaacca acttagcgat ttcacgtaat tggtcataac
    10201 taaaggtcgt tggcagacga aggccaaaat ctttctcacc gacatagata cggtctacgc
    10261 cagcttcgag tagttgttca acttgttcaa tactttcagc agttgctgta atgacaatct
    10321 tttccataag aaaaattata ccacatttct ccaaaatcag ccatgctttg aaaatgaaaa
    10381 gggactttat tctttttgta acctttctgt aataattctc tgccgaaaaa atgataaaat
    10441 aggtatgtac tgttaaggag agaatcatgc ccgtaagaaa attacaatcc tatgaggtag
    10501 actatcaaga agaattaaac cagcagcttc ctcattacca agcttataca cctgaagcgc
    10561 aatctgatgc caatctcaag gaaatcctat tttttattaa tatcgctgtt ttttgtatct
    10621 gtattgctat ctttagtttt atctttttag cattaaaatt atcaactgct cttgcctttg
    10681 ccgcagcaat cggattcagc ttacttgttt taaaagttca acggtctatt atcaaacgaa
    10741 aacgtagaag ataaatccaa aatatcgccc caattggagc gatattttta ttttttcttt
    10801 ttagatggtg tctgaatggc aatcttcact tcaaagattg ttcccttggg tttattatct
    10861 ttgacagtaa cagttccttt tagagcatct acaatttgct tggctaggga taatcctaaa
    10921 ccaaaaccac ctttttgccg ggttctagcc ttgtctactc gataaaaacg gtcaaaaatt
    10981 ttctttttat cttctgtcga aataccgatt ccattatcag aaacaagtaa ataaagattg
    11041 cgatcggtcg ccgagataag aaaatcaatt tcaccatcct cctcagtata cttgacggca
    11101 ttatcgaaaa gaatggtcat cagttgtttc agaagaagct gatctgtgac aattgttcga
    11161 tggatacgat tttcaaaacg gaagacacga ttattttccg aagcaatcat ctcatagttt
    11221 gtgaaagttg tattaaaaaa gctagttgga acttctgcaa gctccggctt aatcccatca
    11281 tctctccgag ctaagttcag caagcttgtc gttaaaaaac gcatatttcg gacttcttcc
    11341 aaactcgatg caatgctttc gctcacatcc ataatggtag cttctggctt acgaaaaagg
    11401 gtctctaagc gattttgcaa aactgcgagt ggagttcgta actcatgact ggcattttcc
    11461 acaaaagact gttgcttctg catactctca agcaagggcc taacactgac cctagctaga
    11521 tagagactgg caagtaaaga caaaatccag aaactagcca tcacgaccac aatcaattgc
    11581 tcatgctttt gactagcctg ctccaactga ctggtattaa tcaagacagc agcatacttg
    11641 atattggttg aaaccgaact aatattggtc tccatcaaaa tcacacgata gatttcttcc
    11701 tgcccatagc tattaaaaac ctgaatctgg tagatatgtc ctagttcttt cttttctaac
    11761 ttaatcttat ccaagcccaa aaatcgattt ccagaaagaa gttgagtaaa gtctttatca
    11821 aagagaatga cttccgtatt ggaactgaca ttaggtttta tttctacttt actagcgtcc
    11881 gccctagcat tttctaaatc tttaatctct tctgttgccc tatttatagc cagctgaata
    11941 actgcttgag gattttcact cagtccatga agcttatcgt ccaccgaagt ataaagactc
    12001 gaatgcatga cttgtaaaat aatcagagtc attgtagaaa aaatcagggt gaagacaccg
    12061 aagttgcgga taaaataact aaagtcatcc gcataccatg tttttttaag tttactgaac
    12121 atcttttaaa agatacccaa cactacgcaa ggtttgcaaa ttctctgcaa aagtggttcc
    12181 ctttaatttc ttacggactt ttgaaacata gacttcgaca accgaaatcg ttgtatcact
    12241 atcaaatccc catagacggt caaaaatctg cgtcttaggc aaaatcacat tttgattttg
    12301 aaggaaataa actagtaaat cgaactcttt ccccagcaat tcgacaggag tatcttcaac
    12361 tttaacggta ttggttgata aattaaccac gatattccca taagtcaagg tgttttcatt
    12421 aaacttccct gaacgtttga gaagggcctg aatccgcatt ttaagttctt ctaggtagaa
    12481 aggtttggtc agataatcat ccgctcccag ttcaaatcca tgtcccttgt catccaaact
    12541 ttccttggca gtcataatca gaactggtgt cgtaattccc ttttcacgca attcttttaa
    12601 gacttggaaa ccattttttt ctggcaacat caaatccagc aaaatcaagt catagacacc
    12661 actctcagct tcgtagagac cttcttctcc atcaaatacc tgcataacat ccgcaaaatc
    12721 gtctaaaaag tcaaatactg aatttgacag acctaggtca tcctcaacca ataagatttt
    12781 tatcatgaga aactcctcct tattaaaact attataccaa atttgcctta aaaaaaactc
    12841 aactctctgc attttacatg agatagctga gttttctttt tattttaggc ttatttatgc
    12901 atttccgtat tgaagaacaa ctgcttcgac tgcagctttt tcacggctaa tcaagtcaac
    12961 acgtgctgca atttccttga ttcccatacc gatgttacgg ctaagagcaa ggtcagaaag
    13021 ttgcggctca aagaactcct tgtattccgc caagcgttgc tgagtcttaa atacatgagc
    13081 aggaaggata acaaagctat caaagctcat atctcctcca agggctgcct taatccaagc
    13141 ccagttttca cgcgcccaag accaagctgt tttctgagtt gcttgatgag ctaggaattg
    13201 gtaataccaa gcagacaagt cctgtggttt gaccacaaat ttgtccttcc aagaagtaat
    13261 caagttttgg atattatccg catctgtact gtatgcaaga gctgctgcca actggcgttt
    13321 aaagacagca tctgttgcgt gagtataagt atcaagataa agtgctaaca agtctttagt
    13381 ctcatgatgt ttcatctcat taatcagaac ttgtgaacga atagctgctg ggagtcctgc
    13441 aagattctcc ttgtgtgttg cgaagatttg gctagcgact tgactagctt ctgcatcatt
    13501 tgagcgaatc atcatcgaaa cagccagctg acgaaccaat tcatcctcat ctgattctcc
    13561 gtctttagct tcaaaaccaa gacggtcata gttatgacga gccaatttag caaccagtcc
    13621 tttgaaggct gtttcagcat ccgttccttc atcaataaag cgctcaaggg ctgaaatcac
    13681 ttgagaaaca gctgaaacca ccagataaga ctcttcctta gcaagtttat caagaactgg
    13741 aagcaagtct gcataagaaa tgtgccctgc ctcagccaac aaacgacgtt cttgaacaat
    13801 ttgcagtttg cttgtgttat caagtgtctc tagctcagca agaacagctt ctaacaagtc
    13861 tccttgatag tcggtaatat agtgggcagt attttcagtg ttgagacgaa gagctccttc
    13921 attttcagca agaagagctg cgtagccagg gatttcgata ctttcagttt cgagtgtatc
    13981 aggcaagcct ttccagttgc tattgagggg caccacccag agacggttct tgtcttcgtt
    14041 ctcaccgatg aagaattgtt tttgtgaaat cttcaagaca tcattttcaa ctttaacagt
    14101 aagaactggg taaccaggct gttccaacca agaatccatg aaggctgcga catcacgtcc
    14161 tgacgcttga ccaagggcat cccaaaggtc actaccaatg gtgttgctgt attggtgttt
    14221 ttcaaagtag gcgtgcaaac ctttagcaaa atcagcatct cctagccaac ggcgaagcat
    14281 gtgcatgaga cggcttcctt tggcatagac gatagcgccg tcaaagagtg tattgatttc
    14341 atctggatgt ttaacttcga cgtggacaga ctgaacgcca tcagtagcgt cacgttcaag
    14401 agcaagaggt actccacctg tttggaaatc ttcaaagata ttccagcttg gttcgatggt
    14461 atccacacag acgtattcca tcatattagc aaaactttca ttgagccaaa ggtcatccca
    14521 ccatttcata gtcacgaggt tcccaaacca ttggtgagcc aattcatggg ccacaacaag
    14581 ggcaacttgt tgacggctag caaatgtaga gttctcatcg acaaccaagt aaacttcacg
    14641 gtaggtcaca agaccccagt tttccatagc accagctgag aagtcaggaa gggcgatgtg
    14701 gagagattga ggaattgggt acttaactcc atagtaatct tcgtaaaact cgatagagcg
    14761 aacagcgata tccagtgaga aatcaagatt tgaaagtgga tgtgctttgg ttgagtagac
    14821 acctaccagg gtaccatttt tagttttagc ggtcacccct tgcaaatcac cagcaacaaa
    14881 ggccaacaag taagaagaca tgcgaggtgt tgtctcaaac ttccagatac ctgtttcctt
    14941 acggttttca acatcgattt ctggcatgtt tgacaaggcc aattcacctt ctgcttggtc
    15001 aaagcgaaga gagagatcaa aagttgcttt ggcttcaggc tcatccacac atgggaaagc
    15061 ttcgcgcgca aaatggctct cgaactgagt agacaagacc tccttcttga ctccatcaac
    15121 tgtataataa gaagggtaaa tccctgtcat gttgtctgta attttaccag aaaaggcaag
    15181 aaccaattca acttgaccag cctcagccaa ttcgatatga agggcttcat tgtcatggtc
    15241 aactgtaaat ggacgagctt gacctgcaac ttctacagag gtgatttcca agtctttttg
    15301 gtggagggag atgcggtcac tctgtgcttg accagtgatg gtcactttcc cagaaaaagt
    15361 cttggtctca cgactcaaat ctaaaaataa atcataatgt tcaggaacaa attgcttaat
    15421 aaaatgttca actgcttgca tagttttctc ctattctaag tttaagagct gctgctcttc
    15481 ttcaaacaaa cttattatat catattttgc ttgagaaaaa aggattggac agcgatttcc
    15541 aaaactttct tccttctaat agtctacagt gggtagacct tgcgaaattc ttctaaaaca
    15601 accttgcttt caggtgtaaa agtcagccct acttcaccca aacagtctgt gaaaaagtcc
    15661 tcatgagcct ggcgccaata ggcaagtgat ttgtctccct caccttcctt aaaggcatgt
    15721 tgcgcagaga cttgattgaa gagttcaaca gaaacctttg taatttcgac aatgcagaca
    15781 gactgatttt gactatctaa aatgacatcg aaggtcccta cttggggaag tggttcgtct
    15841 tctagtacat agaggtcata ggctgatgct gttgctgtct tttctccttt aaacaccaaa
    15901 tccgctaaaa ggtctggttc aactccaaaa gcccaagcat cgatttcatc tccgatcaaa
    15961 ggattgattt gcttgtattt attccacatt tcttgcggta tcatgggtac tcctttgtaa
    16021 ttttttactt tcttctttta tgtgtttaag atgatctgga tggtcaatct ctaaatcaaa
    16081 aatctctgga atagaactgt agtggataat gcacttgata cccaactgat tcattttttg
    16141 tatgaaagaa gtattcagat agcctgctac agcaaaatta atcttgttct ttcttgcttt
    16201 atcctgcata tctcttagca tatctaacat tattggactt tccatatcat gccattgact
    16261 gtttctcata gtcgcaaaaa caaaggaagt caaatcattc attccaacta caatctttga
    16321 aatgcccgtt tccagtatac tagataagtc aaaatacgct gacggtaatt caatcatcgt
    16381 tccgactttc ccagtaaagc catactgacg caatactgta atagcttgtt ttaattggtc
    16441 ggcatcattg acagaaggaa agataagaga tagattgggg ttggtttgat aaacttctgt
    16501 aacgacatgt gcttcagcct gaaattcatc caaacacgcc agtaaacgtc tggttcctct
    16561 atagccaaac aagggatgcc cttcgtcaaa aaactctcta gtccccacta aacaattggc
    16621 ttctgtattc gttaattcag aaaaacgata ccaaacttct tcatctgagt acagggagca
    16681 gatagtctct agataatctt ttacaaattg ctgacaactt gctaatatga tgttttgatt
    16741 aagctctctc aacaaatatt ccccacgaat catgccgacg tggtgaaata gttgaggata
    16801 aattttttca agaatttttt cgccactaag ggcaagttga tttctcatag ccattcacct
    16861 cgtcttaaaa gatacaatat catatataat tatatcaaaa tttcctctag ttcaaaagct
    16921 tcataaggtt cagataactc atatcctaaa aattctgcta cttttttgga agcctcatta
    16981 tgagcatccc aaagtggaaa catatctcta tttaaactct ctagaatcat tgcagcacca
    17041 agctttttag caaatccatt tccttgttcg tttggtctag ttgcaacttc cacttcaact
    17101 gctttacggt aaactaaccc tgaggaaatc ccagcaatca gttcattatt tttaagaatc
    17161 acaaagccaa atccaccttt taaaacaaaa tcctgatagg actcaaaatc cccctgtaaa
    17221 tcctgtgacc attcttccgt agaaaagcag ttataaatat gattatcaat aggcacaata
    17281 ttgtaacctt cctctaaatg agtaactaga ttatttaaaa attcaacttg aaaatttgcc
    17341 ttatctttaa aagaatagcg agtaaaagaa tttagcccca cttttcgatg cagaaaatct
    17401 tgccaattag tattttctga aataataatc ttataatcta aaccatattt tctaacaaaa
    17461 tcttcccaaa atctggaatc caactcccct gctaggtata gaaaattccc aacatcataa
    17521 aagcttgttg tcctatcatt gtttcggtag acagttccaa tttgagattt aagaccatag
    17581 agaaccatat ttttcttcca tgttttaaat agttccatta tccctctact tcaccttcca
    17641 attcatgtaa gaagtcttgt ccagttctgg caatcctaat aattcagact taaccttcaa
    17701 gactaatggc gatgcatttt cttctgtaat ctcttgaata tccatccaaa tatatccaag
    17761 tgaatcattc gcaccatcag acacagcttc cgaaatcgta acttgaggtg cactctcatt
    17821 catttcaaca tcatacaagg ctatgacatg gtgaaccata aaatttttta actcttccct
    17881 gacgaaaaca tcgtagattc gaggattaga gtagcttcta acagtaaatc ccgtctcttc
    17941 cataacttct ctagtcagcg tttccgtcag tccttcacca agttgctgac tgcctccagg
    18001 tagatcatac cgatgttgat aagggcctct cgttttttca atgcaaagta actttccatt
    18061 ttcaaagcaa acacagtaga ccccaaagtg atttttgatt tccatccaac tcctcctact
    18121 tcaaagacca gccaccatct attgtcagaa tttgtccctg catggcagat gcctttccac
    18181 tggccaaaaa gagactgact tctgccactt cctctggttc aatccagcgc ttgattggtg
    18241 tttcactagc cacccagtca gctaagccac ctgtctcaaa atccgcagcg gtcatagctg
    18301 tcttgactgc tcctggagcg ataccaaaga cctgaatccc agcttcagca tagtctagag
    18361 ccaactgctt ggtgaagcca gccaaggcat gcttggatga agtataggcg tgaccacctc
    18421 cacctgctag gctagaagca atggaacaca tattgatgat gattcccttt ttattttcca
    18481 gcatttgtgt caaataatac cgagtcaact ctactggaat aatgtagttg atttcaaaaa
    18541 tctcttgaat gtcctgcgcc gtttgttcca acagtggttt gtaatcatcc aaaactccag
    18601 cagtattaca caaaacatcc acctgagggc accagtcaaa aataggttcc aagtccaagg
    18661 tcaaatctct ctgtaaaaag cgaaaatcac cctctaagag tggcttttca ccttggtcaa
    18721 ctccataaac ttgatagccc ttctctaaaa agaggcgagc ttgagccaat ccgatccctg
    18781 aactcactcc tgtaatgagt acacgtttag tcatgcactt ctacccaatc cgttgccaaa
    18841 acatcacaaa ctgtcgggct ccacatggaa aaaccttctc cttcgccaga aacgttgatt
    18901 aggaaataag gtgtcatttc aagtgcaagc ccattttgct cgatggtatc aaagagttgg
    18961 acatagtttt ccgcacctcc ccaaccagtt cgtacatatt ttctcttagc ctttaaccca
    19021 ggcaggatct cttcaaatgt catgtttttc tcctttaatt ctacattctt catttaatta
    19081 tagcaaaaaa ccgctttata cggctttttg aatgtgagtt attcaaacct gctactactt
    19141 acggcaaatt attccctgca gcaagataaa tttcatacca ttcttttctt gttaagctaa
    19201 agtttgccgc tcggctaact tctctcaagt gcttaggatt tgttgtacct acgactgcct
    19261 gcatttttgc tggataacgc aatatccaag aaatggcaat agttgaagag gttactccat
    19321 atttaatagc taaacgatca agtacttgat ttaaagcttg aaatttctca tttccaacaa
    19381 aattcccttt aaaatacccg aattgtaaga cagaccatgc ttgaatgacc acatcgtgta
    19441 attggcaata ttcaaaaatg ctgccatctc gcatagctgc ttgactatct tccatattaa
    19501 catgaaaagc tgattcaaat cctggagtaa aagccgcact caattgtagc tgattaacag
    19561 ctaacggctg cttgacatct tttttaagca actccatcat cataggattt tgattagaaa
    19621 ctccaaaatc tcgaacttta ccttgtttat aaaggagatt aaaggcttct gctacttggt
    19681 cagattccat caaagcatct ggtcgatgaa ggagcaagct atctagatga tcaatcttca
    19741 atctttgcaa aataccgtct actgatttta taatatagtc cttagaaaaa tcaaaatagg
    19801 taaattcttc aatgcgaatg ccacatttgg actgaatcca catcttttct cttaaatctg
    19861 gacgattttt taggacaaga cctaacagtt cttcacaacg accacgacca taaatatcag
    19921 ccaagtcgaa ggcattgatt ccaacagaaa gtgctgtttc tacaagctct tcaacttctt
    19981 ttacagattt atcttttatt ctcatcattc cgagaacaat ttctgataat tctttgtcat
    20041 cttgaccaag agttatgtat ctcatcaaat ttttctcctt taatttctaa cattcttccc
    20101 ttcattataa caaaaaaccg ctttgcaacg actttttgac tatacttcac tccattttat
    20161 cttcttaaac ccacggaaca agacaaagat tccaataaag aggacagcta aaggaataac
    20221 ttttgtaagg aaaacatttg aaattcccat ccactcataa taacggagca gagaacccac
    20281 cacaagatgg gcaataatca tactgacaaa tggacgaaag accgcttctt tccaattcca
    20341 aataccgata actagcgaaa tcgtaaagac agacaaacta tcccagggag ccggaatata
    20401 aaaggctcct tcttgtatga agcttgccat tcctacatat cctaaaacaa ctagaagaac
    20461 tatagtccca acaacaatgt aagtgccaat tttcatttta ggagaatctt ggactaaact
    20521 tcttcgtaaa attgtggcca caagtccaaa tccaatcaga aaaataagaa gttgccctaa
    20581 aaatgtgagc aaattgactg ttaagagagg acctttagaa aaatcactta gtagttgata
    20641 ataacgtaat accgccagga caagaattgg cgtcaaaagg gactctttga tagaactgcg
    20701 aggtgctccc ttgagaatct ctttcattat ttttttagga ttcttaccta gataatcctc
    20761 tgcactcatg ccatctcgtt ctgcttctga gaaatctagc atcatcaaat agatctgctc
    20821 tctgagatag tcttcatcat agagaaatcc agcaagatta aaactttccc acaactcctc
    20881 aaaatacttt tgattctcct cagaaaactc atgtagcaaa gcgcttgttt cttcgtaata
    20941 cttcattttc ttcatggttt aacccccatt cttaatccct tctacttttt gactcaaatc
    21001 gtcccattgt tgccaaaaga ctgagacacg ctcttctcct tctttcatta atgaaaaata
    21061 cttccgatct ggaccatctg gcgacgggcg catgtcgcct cttatccatt gatttttttc
    21121 taacttttgc aacaaaggat aaatagttcc tggaacgata gtatcaaatc cagcctctcg
    21181 caaagtctga accaactcat aaccataccg ctctttttga ccaatcatat ccaagacaca
    21241 accttcaaga acacctttta atagctgagt ttctttcatc acttctccct tctaatctat
    21301 tttgtaatac ctactagtga cttcacctat agtatatcac ttctacacta gtttgtaaag
    21361 cataatagtt aatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cctaccgtat
    21421 gtatggttac tgacttcgtc agtttcatct acaacctcaa aaacatgttt tgagctgact
    21481 tcgtcagttt catctacaac ctcaaaacag tgttttgagc tgacttcgtc agtttcatct
//
LOCUS       DAVKEV010000038        19507 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVKEV010000038 DAVKEV010000000
VERSION     DAVKEV010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19507
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.038"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..752)
                     /locus_tag="VWZ68_001573"
     CDS             complement(<1..752)
                     /locus_tag="VWZ68_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9372580.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNTPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQI
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHAQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            complement(749..2074)
                     /locus_tag="VWZ68_001574"
     CDS             complement(749..2074)
                     /locus_tag="VWZ68_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9372581.1"
                     /translation="MDFFLLVDLILYFLIISHSYRLICKDQINRKELFFFGAYTLLTE
                     IVLDFPFYLLYLDGLGIATFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYYGLFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRVYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKRKFE"
     gene            complement(2087..2227)
                     /gene="comC"
                     /locus_tag="VWZ68_001575"
     CDS             complement(2087..2227)
                     /gene="comC"
                     /locus_tag="VWZ68_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEU9372582.1"
                     /translation="MKNTVKLEQFVALKEKDLQNIQGGEMRKMNEKSFNIFNFFNFFR
                     RR"
     gene            complement(2392..2465)
                     /locus_tag="VWZ68_001576"
     tRNA            complement(2392..2465)
                     /locus_tag="VWZ68_001576"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2429..2431),aa:Arg,seq:tct)
     gene            complement(2509..2988)
                     /gene="rlmH"
                     /locus_tag="VWZ68_001577"
     CDS             complement(2509..2988)
                     /gene="rlmH"
                     /locus_tag="VWZ68_001577"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEU9372583.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            3171..4352
                     /locus_tag="VWZ68_001578"
     CDS             3171..4352
                     /locus_tag="VWZ68_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEU9372584.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            4410..5168
                     /locus_tag="VWZ68_001579"
     CDS             4410..5168
                     /locus_tag="VWZ68_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEU9372585.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNYFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIIYFSNQEEYSRIINSLK"
     gene            5381..6742
                     /gene="dnaA"
                     /locus_tag="VWZ68_001580"
     CDS             5381..6742
                     /gene="dnaA"
                     /locus_tag="VWZ68_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEU9372586.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            6901..8037
                     /gene="dnaN"
                     /locus_tag="VWZ68_001581"
     CDS             6901..8037
                     /gene="dnaN"
                     /locus_tag="VWZ68_001581"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEU9372587.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTIKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            8102..8296
                     /locus_tag="VWZ68_001582"
     CDS             8102..8296
                     /locus_tag="VWZ68_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEU9372588.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            8380..9495
                     /gene="ychF"
                     /locus_tag="VWZ68_001583"
     CDS             8380..9495
                     /gene="ychF"
                     /locus_tag="VWZ68_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEU9372589.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLIESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYESEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            9566..10135
                     /locus_tag="VWZ68_001584"
     CDS             9566..10135
                     /locus_tag="VWZ68_001584"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEU9372590.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     KADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            10136..13645
                     /gene="mfd"
                     /locus_tag="VWZ68_001585"
     CDS             10136..13645
                     /gene="mfd"
                     /locus_tag="VWZ68_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEU9372591.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDYDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKELMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            13703..13969
                     /locus_tag="VWZ68_001586"
     CDS             13703..13969
                     /locus_tag="VWZ68_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEU9372592.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            13962..14330
                     /locus_tag="VWZ68_001587"
     CDS             13962..14330
                     /locus_tag="VWZ68_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEU9372593.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGVVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            14450..15718
                     /locus_tag="VWZ68_001588"
     CDS             14450..15718
                     /locus_tag="VWZ68_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEU9372594.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKISFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            15715..16992
                     /gene="tilS"
                     /locus_tag="VWZ68_001589"
     CDS             15715..16992
                     /gene="tilS"
                     /locus_tag="VWZ68_001589"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEU9372595.1"
                     /translation="MREQDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNIDVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            16996..17538
                     /gene="hpt"
                     /locus_tag="VWZ68_001590"
     CDS             16996..17538
                     /gene="hpt"
                     /locus_tag="VWZ68_001590"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEU9372596.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            17554..>19507
                     /gene="ftsH"
                     /locus_tag="VWZ68_001591"
     CDS             17554..>19507
                     /gene="ftsH"
                     /locus_tag="VWZ68_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEU9372597.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQNPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
BASE COUNT         6738 a         3129 c         3649 g         5991 t
ORIGIN      
        1 cacttttgag attttttctc taaaatatct tttaattttc taatttttaa tcttgaaata
       61 ggacaacgat ggtcttcata gaaaacaatt tctaagtttt ttcgatcaat ttctctgata
      121 ttgcctatat ttaccaaaaa tgacttgtga ggagaataaa atcgctgagc atgtttgtcc
      181 ttttcctgaa tatctgtcat ggtaccataa aactcttttg caaaattctt accaataatg
      241 cgcaatttat gagagactcc tgtcgtttca atatacaaaa tatcatggta aggaattttt
      301 aaatcatttc ccttgtaatt gtagtcgaaa taatctacaa catcttcatt ttcaagtaac
      361 atactcttcg tgtagaagat attttgctca attcgcttct taaacatctc atcgttgata
      421 tccttatcaa caaaatctag ggctgatatc tggtatttat aggtcagagt cgcaaactct
      481 gatcgactgg tgataaagac gataatagcg taaggattgt aatgacgaat gagttgagca
      541 acttcaaatc cctttttctc aattccatga atatcgatat ctaggaaata aagttgattt
      601 acttcatcat tttcaatgta ttcttcaaat tcacggactt ttcccgttgt cttgtatgat
      661 attggagtat tcgattcttt cgaaatttca tccaatattc tctctagtct cacttgatgt
      721 tcaataacat cttctaaaat taaaactttc attcaaattt cctcttaaat ctaatgattt
      781 gtctaaatgt actgccttcc atctctgttt ctaaaataat gttgttgtac ttatctagta
      841 gttctttcac attatttaat ccgactccgc gatttcttcc cttagtggag aatcctaagg
      901 caaatagatc tcctgaagga gtcatcgtca ttttacatga attctgaatc acaataactg
      961 tttcagtttc catcttaata actgctactt ccatctgctt tttatagcta tcagccgatc
     1021 cttcgacagc attgttcaat aaaacgctca tgatacgcac taaatccaat agttcaattg
     1081 gaagcttggt aatcgtatct tttacttcca gtgtaaactc tacaccatta tttcgagcat
     1141 agacaattga ctgagcaacc aaacttcgta aagctgaatc ttctatgttg ttcaaatcaa
     1201 agtaagtgta cttatctgaa cgtagtttat gatttgcttt gaccaaaact tcattgtaaa
     1261 ctctgtcaat ttcctgtaaa ttaccactgt caattgccat ctgcatgctg acaagcattc
     1321 cagcataatc atgtcgaaaa ccacggattt cattatacag accgacaatt tcatctgtgt
     1381 aattctgtaa atgtttctgt tcaaatttct tctgcttcaa agcaatctct ttctccattt
     1441 gaactttatg agaattcatt gcaaagaagg tcaaaaggag agagataaag acaatagatg
     1501 acaaaatact tccaaaacta ttcaaatgtt taatcgtact taccatatct gaaacgaaag
     1561 atacaatatg tagcaatagt aaagcaaaaa atactttttt caagaaagga taaaggtagt
     1621 ccttgtcaaa ataggctagt tccaaatgga aataataaat gatttttaat gtaacaaaat
     1681 aggtcaacac cgtcacaacg aaaaagaata ggccataata ctgtaaaaca aaattgtctc
     1741 ctgttataga agagaaagtt acggacagaa agttatgagt gctctcatat aaaagagata
     1801 gtagtaaact tagaaatagt cctctatccc tctcatactg tttcatccat cgaaaatagg
     1861 aatataggcc caaaggaaat aaaaatgttg caatccctaa cccatctaaa tatagaagat
     1921 agaagggaaa atcaagtact atttctgtta gtaatgtata agcaccaaaa aagaataatt
     1981 cttttctatt tatttgatct ttacaaatta aacggtaact atgactaata attaaaaaat
     2041 ataatatcaa atctactaat aagaaaaaat ccattctgct actcctttat cttcttctaa
     2101 agaaattaaa gaaattaaag atattaaagg acttttcatt cattttcctc atctccccac
     2161 cttgaatatt ttgcaagtct ttttccttca aagctacaaa ctgttccaat ttaactgtgt
     2221 ttttcataat aaaatctcct aaaatgtttt ttcttgtaag ctaacttaca aaaaccatta
     2281 tacaaaatgg aatttcgttt tagataaaat tctctcaact gtcatttttt tctcccaaag
     2341 tgtacttttt taagaaaaaa gccgggaaaa ttcccagctt tgctattata ttgatcccag
     2401 caggattcga acctgcgacc gttcgcttag aaggcgaatg ctctatccag ctgagctatg
     2461 agacctaaca caattattct accaaaaatt caattaaaag tcaattttct atttatggta
     2521 ggggaatccc tgctgaatcg taaaagcgcg atagatttgt tcaacaagaa ctagtctcat
     2581 taactgatga ggcaaggtta ggcgaccaaa actgacagaa agattggctc tattttttac
     2641 agatgatgat aatcctaaac ttcccccaat aataaaagta agagtagaaa atccttttat
     2701 agaagtttct tctaactgct tactaaattc ttctgagaag aaagttttcc cttcaatggc
     2761 taacacaata acgaaatcac ggtcagcaat ttttgataaa attctctgac cttctatttc
     2821 taaaatcttt tgattttctg attcactggc cttatctggt gttttttcat ctgataactc
     2881 aatcatttca aacttagcaa atctagaaat tcgttttgaa tactctgcga taccatcttt
     2941 taaatacttt tctttcagtt tcccaactgt tacaacttta attttcatga ctctattcta
     3001 acatattctc tattttttca catcttattc acaaaataaa aaatagattt caattaagaa
     3061 aatcacagtt tcaaaagagt tatccacagt ttgtgtaaaa cttttgtgtt taagttataa
     3121 ttaagctagt cagtttatac tttcagtaat tcaaacatat ggaggcaaat atgaaacatc
     3181 taaaaacatt ttacaaaaaa tggtttcaat tattagtcgt tatcgtcatt agctttttta
     3241 gtggagcctt gggtagtttt tcaataactc aactaactca aaaaagtagt gtaaacaact
     3301 ctaacaacaa tagtactatt acacaaactg cctataagaa cgaaaattca acaacacagg
     3361 ctgttaacaa agtaaaagat gctgttgttt ctgttattac ttattcggca aacagacaaa
     3421 atagcgtatt tggcaatgat gatactgaca cagattctca gcgaatctct agtgaaggat
     3481 ctggagttat ttataaaaag aatgataaag aagcttacat cgtcaccaac aatcacgtta
     3541 taaatggcgc cagcaaagta gatattcgat tgtcagatgg gactaaagta cctggagaaa
     3601 ttgtcggagc tgacactttc tctgatattg ctgtcgtcaa aatctcttca gaaaaagtga
     3661 caacagtagc tgagtttggt gattctagta agttaactgt aggagaaact gctattgcca
     3721 tcggtagccc gttaggttct gaatatgcaa atactgtcac tcaaggtatc gtatccagtc
     3781 tcaatagaaa tgtatcctta agatcggaag atggacaagc tatttctaca aaagccatcc
     3841 aaactgatac tgctattaac ccaggtaact ctggcggccc actgatcaat attcaagggc
     3901 aggttatcgg aattacctca agtaaaattg ctacaaatgg aggaacatct gtagaaggtc
     3961 ttggtttcgc aattcctgca aatgatgcta tcaatattat tgaacagtta gaaaaaaacg
     4021 gaaaagtgac gcgtccagct ttgggaatcc agatggttaa tttatctaat gtgagtacaa
     4081 gcgacatcag aagactcaat attccaagta atgttacatc tggtgtagtt gttcgttcgg
     4141 tacaaagtaa tatgcctgcc aatggtcacc ttgaaaaata cgatgtaatt acaaaagtag
     4201 atgacaaaga gattgcttca tcaacagact tacaaagtgc tctttacaac cattctatcg
     4261 gagacaccat taagataacc tactatcgta acgggaaaga agaaactacc tctatcaaac
     4321 ttaacaagag ttcaggtgat ttagaatctt aattgacatc tatgtaaaga aagctttaca
     4381 taagagaaaa gatgtgttag tgtagaatca tggaaaaatt tgaaatgatt tctatcacag
     4441 atatacaaaa aaatccctat caaccccgaa aagaatttga tagagaaaag ctagatgaac
     4501 tagcacagtc tatcaaagaa aatggggtca ttcaaccgat tattgttcgt caatctcctg
     4561 ttattggtta tgaaatcctt gcaggagaga gacgctatcg ggcttcactt ttagctggtc
     4621 tacggtctat cccagctgtt gttaaacaga tttcagacca agagatgatg gtccagtcca
     4681 ttattgaaaa tttacagaga gaaaatttaa acccaataga agaagcacgc gcctatgaat
     4741 ctctcgtaga gaaaggattc acccatgctg aaattgcaga taagatgggc aagtctcgtc
     4801 catatatcag caactccatt cgtttacttt ccttgccaga acagattctc tcagaagtag
     4861 aaaatggcaa actatcacaa gcccatgcgc gttccctagt tgggttaaat aaggaacaac
     4921 aagactattt ctttcaacgg attatagaag aagatatttc tgtaaggaag ttagaagctc
     4981 ttctgacaga gaaaaaacaa aagaaacagc aaaaaactaa ttatttcata caaaatgaag
     5041 aaaaacagtt aagaaaacta ctcggattag atgtagaaat taaactatct aaaaaagaca
     5101 gtggaaaaat cattatttat ttttcaaatc aagaagaata tagtagaatt atcaacagcc
     5161 tgaaataagg ctgttctttt atttttttat ctcacaaggt tatccactat gtttttcgat
     5221 aaaaagctta ataaatcaat aatttcttct tttatcccca acctgtggat aaagtttagt
     5281 aacattgtgg attatttttc acagcttgtg gaaaattctt gctatctatg gtaaaatatc
     5341 tctagtatta aacttttaaa tagtaaagga ggaaaaagga ttgaaagaaa aacaattttg
     5401 gaatcgtata ttagaatttg cacaagaaag actgactcga tccatgtatg atttctatgc
     5461 tattcaagct gaactcatca aggtagagga aaatgttgcc actatatttc tacctcgctc
     5521 tgaaatggaa atggtctggg aaaaacaact aaaagatatt attgtagtag ctggttttga
     5581 aatttatgac gctgaaataa ctccccacta tattttcacc aaacctcaag atacgactag
     5641 ctcacaagtt gaagaagcta caaatttaac tctttatgac tatagtccaa agttagtatc
     5701 tattccttat tcagatacgg gattaaaaga aaagtatacc tttgataact ttattcaagg
     5761 ggatggaaat gtttgggctg tgtcagccgc tttagctgtc tctgaagatt tggctctgac
     5821 ctataaccct ctttttatct atggaggacc aggccttggt aagactcact tattaaacgc
     5881 tattggaaat gaaattctaa aaaatattcc taatgcgcgt gttaaatata tccctgccga
     5941 aagctttatt aatgactttc ttgatcacct aagacttggg gaaatggaaa agtttaaaaa
     6001 gacctatcgt agtcttgatc ttttgttaat cgatgatatc cagtcactca gcggaaaaaa
     6061 agtcgcaact caggaagaat ttttcaatac ctttaacgcc cttcatgaca agcaaaaaca
     6121 gattgtccta acgagtgatc gtagtccaaa acatctagaa gggctcgagg agaggcttgt
     6181 cacgcgtttt agttggggat tgacacaaac tatcacaccc cctgactttg aaacacgtat
     6241 tgccatttta caaagtaaaa cggaacattt aggctacaat ttccaaagtg atactctaga
     6301 atacctagct gggcaatttg attcaaatgt tcgagatctt gagggagcca tcaacgacat
     6361 cactttaatt gccagagtaa aaaaaatcaa ggatatcact attgatattg ctgcagaagc
     6421 cattagagcc cgcaaacaag atgttagcca aatgctcgtc atcccaattg ataaaatcca
     6481 aactgaagtt ggtaactttt atggtgttag tatcaaagaa atgaagggaa gtagacgcct
     6541 tcaaaatatt gttttggccc gtcaagtagc catgtattta tctagagaac taacagataa
     6601 tagtcttcca aaaattggga aggaatttgg gggaaaagat cataccacag tcattcatgc
     6661 ccatgccaaa ataaaatctt tgattgatca agacgataat ttacgtttag aaattgaatc
     6721 aatcaaaaag aaaatcaaat aatttgtgga taacttttag ttttttatct tttttatcca
     6781 cattttttaa acaagctaaa aaacttgata ggacttgttt aaaggctgtt ttccacagat
     6841 ttcacagact ctattattac tattatcttt ctaatactaa aaataaataa aggagaatcc
     6901 atgattcatt tttcaattaa taaaaattta tttctacaag cattaaatac tactaagaga
     6961 gctattagtt ctaaaaatgc cattcctatt ttatcaacaa taaaaattga cgtgaccaat
     7021 gaaggtatta ctttaattgg ttcaaatggt caaatttcaa ttgaaaattt tatttctcaa
     7081 aaaaatgaag atgctggttt gttaattact tctttaggtt cgatccttct tgaagcttct
     7141 ttctttatca atgtagtatc tagtttacct gatgtaactc ttgattttaa agaaattgaa
     7201 caaaatcaaa ttgttttaac cagtggcaaa tcagaaatta ccctaaaagg aaaagatagc
     7261 gaacaatatc cacgaatcca agaaatttca gcaagcactc ctttaatact tgaaacaaaa
     7321 ttactcaaga aaattattaa tgaaacagcc tttgctgcaa gtacacaaga gagtcgtccg
     7381 attttaacag gtgtccactt cgtattgagt caacacaaag agttaaaaac agttgcaaca
     7441 gactctcatc gcctaagcca gaaaaaattg actcttgaaa aaaatagtga tgattttgat
     7501 gtcgtaattc ctagccgttc tctacgcgaa ttttcagcgg tatttacaga tgatatcgaa
     7561 actgtagaga ttttctttgc caataaccaa atcctcttta gaagcgaaaa tattagcttc
     7621 tatactcgtc tcctagaagg aaactatcct gatacagatc gcttgattcc aacagacttt
     7681 aacactacta ttacttttaa tgtggtaaac ttacgccagt caatggagcg tgcccgtctt
     7741 ttatcaagtg cgactcaaaa tggtactgtg aaacttgaaa ttaaggatgg ggttgttagc
     7801 gcccatgttc actctccaga agttggtaaa gtaaacgaag aaatcgatac tgatcaggtt
     7861 actggtgaag atttgaccat tagtttcaac ccaacttact tgattgattc tcttaaagct
     7921 ttaaatagcg aaaaggtgac cattagcttt atctcagctg ttcgtccatt tactcttgtg
     7981 ccagcagata ctgacgaaga cttcatgcag ctcattacac cagttcgtac aaattaagtg
     8041 aaagaggttg agcctggctc gcctctttta tgatataatc gaaaaagaaa aggagagtag
     8101 tatgtatcaa gttggaaatt ttgttgagat gaaaaaatca cacgcttgta caatcaagtc
     8161 gactggtaaa aaggctaatc gttgggaaat tacacgtgta ggagcagata tcaaaataaa
     8221 atgcagtaat tgtgagcatg ttgtcatgat ggggcgatat gattttgagc gaaaaatgaa
     8281 taaaattatt gactgagaac ccttagttag agggttagca ctttatccct ttttgtgtta
     8341 taatattagg gattgaaatg aaaacggaga atgagaaata tggctttgac agcaggtatc
     8401 gttggtttgc caaacgttgg taaatcaaca ctatttaatg caattacaaa agcaggagca
     8461 gaggcagcaa actacccatt tgcgactatt gatccaaatg ttggaatggt ggaagttcca
     8521 gatgaacgcc tacaaaaact aactgaaatg ataactccta aaaagacagt tcccacaaca
     8581 tttgaattta cggatattgc agggattgta aaaggagctt caaaaggaga agggctaggg
     8641 aataaattct tggccaatat tcgtgaagta gatgcgattg ttcacgtagt tcgtgctttt
     8701 gatgatgaaa atgtgatgcg cgagcaagga cgtgaagacg cctttgtgga tccacttgca
     8761 gatattgaca ccattaacct agaattgatt cttgcagact tagaatcagt caataaacga
     8821 tatgcgcgtg tagaaaagat ggcacgtacg caaaaagata aagaatcagt agcagaattc
     8881 aatgttcttc aaaagattaa accagtccta gaagacggga aatcagctcg taccattgaa
     8941 tttacagatg aggaacaaaa ggttgtcaaa ggtcttttcc ttttgacgac taaaccagtt
     9001 ctttatgtag ctaatgtgga cgaggatgtg gtttcagaac ctgactctat cgactatgtc
     9061 aaacaaattc gtgaatttgc agcgacagaa aatgctgaag tagtcgttat ttctgcgcgt
     9121 gctgaggaag aaatttctga attggatgat gaagataaaa aagagtttct tgaagccatt
     9181 ggtttgatag aatcaggtgt agataagttg acgcgtgcag cttaccactt gcttggattg
     9241 ggaacttact tcacagctgg tgaaaaagaa gttcgcgctt ggactttcaa acgtggtatg
     9301 aaggctcctc aagcagctgg tattatccac tcagactttg aaaaaggctt tattcgtgca
     9361 gtaaccatgt catatgagga tctagtgaaa tacgaatctg aaaaggccgt aaaagaagct
     9421 ggacgcttgc gtgaagaagg aaaagaatat atcgttcaag atggcgatat catggaattc
     9481 cgctttaatg tctaaaaatt aataaatggt gtcaattagg ttggaaaaaa attccaaccc
     9541 ttttggcttt tgaaaggaaa aataaatgac caaattactt gtaggcttgg gaaatccagg
     9601 ggataaatat tttgaaacaa aacacaatgt tggttttatg ttgattgatc aactagcgaa
     9661 gaaacagaat gtcactttta cacacgataa gatatttaaa gctgacctag catccttttt
     9721 cctaaatgga gaaaaaattt atctggttaa accaacgacc tttatgaatg aaagtggaaa
     9781 agcagttcat gctttattaa cttactatgg tttggatatt gacgatttac ttatcattta
     9841 cgatgatctt gacatggaag ttgggaaaat tcgtttaaga gcaaaaggct cagcaggtgg
     9901 tcataatggt atcaagtcta ttattcaaca tataggaact caggtcttta accgtgttaa
     9961 gattggaatt ggaagaccta aaaatggtat gtcagttgtt catcatgttt tgagtaagtt
    10021 tgacagggat gattatatcg gtattttaca gtctgttgac aaagttgacg attctgtaaa
    10081 ctactattta caagagaaaa attttgagaa aacaatgcag aggtataacg gataaatggt
    10141 gaccttatta gatttattct cagaaaatga tcagattaaa aaatggcatc aaaatttaac
    10201 tgataagaaa agacaactaa tacttggttt atcaacatct actaaggctc ttgcaattgc
    10261 aagcagttta gaaaaagaag ataggattgt gttattgacg tcaacttatg gagaagcaga
    10321 aggacttgtt agtgatctta tatctatctt gggtgaggaa ctcgtctatc catttttggt
    10381 agatgatgct cctatggtgg agtttttgat gtcttcacag gaaaaaatta tttcacgggt
    10441 tgaagccttg cgttttttga ctgattcatc taagaaaggg attttagttt gtaatatcgc
    10501 agcaagtcga ttgattttac cgtctcccaa tgcattcaaa gatagtattg taaaaatctc
    10561 agttggtgaa gaatatgatc aacacgcgtt tatccatcag ttaaaggaaa atggctatcg
    10621 aaaagttact caagtacaaa ctcagggcga atttagtctt cgaggagata ttttagatat
    10681 ttttgaaata tcccagttag aaccttgtcg aattgagttt tttggtgatg aaattgatgg
    10741 tatcaggtca tttgaagtag aaacacaatt atcgaaagaa aataagacag aactcactat
    10801 ctttccagct agtgatatgc ttttgagaga aaaggattat caacgaggac agtcagcttt
    10861 agaaaaacaa atttcaaaaa ctttatcacc tattttgaaa tcatacctag aagaaattct
    10921 ttcaagtttt caccaaaaac aaagtcatgc agactctcgg aagtttttat ctttgtgcta
    10981 tgataagaca tggactgtct ttgattatat tgaaaaagat actccaatat tctttgatga
    11041 ttatcaaaaa ttgatgaatc agtatgaagt ctttgaaaga gacttagcgc agtactttac
    11101 agaagaatta cagaatagta aagcattttc tgatatgcag tatttttctg atattgaaca
    11161 aatctataaa aaacaaagtc cagtgacctt tttctctaat cttcaaaagg gtttaggaaa
    11221 tctcaaattt gacaaaattt atcaattcaa tcaatatcct atgcaggaat ttttcaatca
    11281 gttttctttt ctaaaagaag aaattgaacg atataaaaaa atggattaca ccattattct
    11341 gcagtctagc aattcaatgg gaagtaaaac attggaggat atgttagagg aatatcagat
    11401 taaattggat tctagagata agacaaatat ctgtaaagaa tctgtaaact taatagaggg
    11461 taatctcaga catggttttc attttgtaga tgaaaagatt ttattgataa ctgaacatga
    11521 gatttttcaa aagaaattaa agcgtcgttt tcgaagacaa catgtttcaa atgcagagag
    11581 attaaaagat tacaatgaac ttgaaaaagg ggactatgtt gtccatcata tccatgggat
    11641 tggtcaatat ctaggaattg aaaccattga aatcaaggga attcatcgcg attatgtcag
    11701 tgtccaatac caaaatggtg atcaaatttc tatccccgtg gaacagattc atctactgtc
    11761 caaatatatt tcaagtgatg gtaaagctcc aaaactcaat aaattaaatg acggtcattt
    11821 taaaaaggcc aagcaaaagg ttaagaacca ggtagaggat atagctgatg atttaatcaa
    11881 actctactct gaacgtagtc agttgaaggg ttttgctttc tcagctgatg attatgatca
    11941 agatgccttt gatgatgctt tcccttatgt tgaaacggat gatcaacttc gtagtattga
    12001 ggaaatcaaa agggatatgc aggcttctca gccaatggat cgacttttag ttggggatgt
    12061 tggttttgga aagactgaag ttgctatgcg tgcagccttt aaagcagtca atgatcacaa
    12121 acaggttgtc attctagttc cgacgacggt tttagcgcaa cagcactata cgaattttaa
    12181 ggaacgattc caaaattttg cagttaatgt tgatgtgttg agtcgcttta gaagtaaaaa
    12241 agagcagact gcaacacttg aaaaattgaa aaacggtcaa gtcgatattt tgattggaac
    12301 acatcgtgtt ttgtcaaaag atgttgtgtt tgctgatttg ggcttgatga ttattgatga
    12361 ggaacagcga tttggtgtca agcataagga aactttgaaa gaactgaaga aacaagtgga
    12421 tgtcctaacc ttgaccgcta cgccaatccc tcgtaccctc catatgtcta tgctgggaat
    12481 cagagatttg tctgttattg aaactccgcc gactaatcgc tatcctgttc agacctatgt
    12541 tttggaaaag aatgatagtg tcattcgtga tgctgtcttg cgtgaaatgg agcgtggagg
    12601 tcaagtttac tatctttaca acaaagttga cacaattgtt cagaaggttt cagaattaca
    12661 ggagttgatt ccggaggctt cgattggata tgttcatggt cgaatgagtg aagtccagtt
    12721 ggaaaatact ctattagact ttattgaggg acaatacgat atcttggtga cgactactat
    12781 tattgagaca ggggtggaca ttccaaatgc taatacttta tttattgaaa atgcggacca
    12841 tatgggcttg tcaaccttat atcagttaag aggaagagtc ggtcgtagta atcgtattgc
    12901 ttatgcttat ctcatgtatc gtccagaaaa atcaatcagt gaagtctctg aaaagagatt
    12961 agaagcgatt aaaggattta cagaattggg ctctggcttt aagattgcaa tgcgagatct
    13021 ttcgattcgt ggagcaggaa atcttttagg aaaatcccag tctggtttca ttgattctgt
    13081 tggttttgaa ttgtattcgc agttattaga ggaagctatt gctaaacgaa acggtaatgc
    13141 taacgctaac acaagaacca aagggaatgc tgagttgatt ttgcaaattg atgcctatct
    13201 tcctgatact tatatttctg atcaacgaca taagattgaa atttacaaga aaattcgtca
    13261 aattgacaac cgtgtcaatt atgaagagtt acaagaggag ttgatagacc gttttggaga
    13321 atacccagat gtagtagcct atcttttaga gattggtttg gtcaaatcat acttggacaa
    13381 ggtctttgtt caacgtgtgg aaagaaaaga taataaaatt acaattcaat ttgaaaaagt
    13441 cactcaacga ctgtttttag ctcaagatta ttttaaagct ttatccgtaa cgaacttaaa
    13501 agcaggcatc gctgagaata aggaattaat ggagcttgta tttgatgttc aaaataagaa
    13561 agattatgaa attttagaag gtctgctgat ttttggagaa agtttattag agataaaaga
    13621 gtctaaggaa gaaaattcca tttgatattt ttcttctata aaatagataa aaatggtaca
    13681 ataataaatt gaggtaataa ggatgagatt agataaatat ttaaaagtat cgcgaattat
    13741 caagcgtcgt acagtcgcaa aggaagtagc agataaaggt agaatcaagg ttaatggaat
    13801 cttggccaaa agttcaacgg acttgaaagt taatgaccaa gttgaaattc gctttggcaa
    13861 taagttgctg cttgtaaaag tactagagat gaaagatagt acaaaaaaag aagatgcagc
    13921 aggaatgtat gaaattatca gtgaaacacg ggtagaagaa aatgtctaaa aatattgtac
    13981 aattgaataa ttcttttatt caaaatgaat accaacgtcg tcgctacctg atgaaagaac
    14041 gacaaaaacg gaatcgtttt atgggagtgg tattgatttt gattatgcta ttatttatct
    14101 tgccaacttt taatttagcg cagagttatc agcaattact ccaaagacgt cagcaattag
    14161 cagacttgca aactcagtat caaactttga gtgatgaaaa ggataaggag acagcatttg
    14221 ctaccaagtt gaaagatgaa gattatgctg ctaaatatac acgagcgaag tactattatt
    14281 ctaagtcgag ggaaaaagtt tatacgattc ctgacttgct tcaaaggtga taaaatggaa
    14341 aatttattag acgtaataga gcaatttttg agtttgtcag atgaaaagct ggaagaattg
    14401 gctgataaaa atcaattatt gcgtttacaa gaagaaaagg aaaggaagaa tgcgtaaatt
    14461 cttaattatt ttgttgctac caagtttttt gaccatttca aaagtcgtta gcacagaaaa
    14521 agaagtcgtc tatacttcga aagaaattta ttacctttca caatctgact ttggtattta
    14581 ttttagagaa aaattaagtt ctcccatggt ttatggagag gttcctgttt atgcgaatga
    14641 agatttagta gtggaatctg ggaaattgac tcccaaaata agttttcaaa taaccgagtg
    14701 gcgcttaaat aaacaaggaa ttccagtatt taagctatca aatcatcaat ttatagctgc
    14761 ggacaaacga tttttatatg atcaatcaga ggtaactcca acaataaaaa aagtatggtt
    14821 agaatctgac tttaaactgt acaatagtcc ttatgattta aaagaagtga aatcatcctt
    14881 atcagcttat tcgcaagtat caatcgacaa gaccatgttt gtagaaggaa gagaatttct
    14941 acatattgat caggctggat gggtagctaa agaatcaact tctgaagaag ataatcggat
    15001 gagtaaagtt caagaaatgt tatctgaaaa atatcagaaa gattctttct ctatttatgt
    15061 taagcaactg actactggaa aagaagctgg tatcaatcaa gatgaaaaga tgtatgcagc
    15121 cagcgttttg aaactctcct atctctatta tacgcaagaa aaaataaatg agggtcttta
    15181 tcagttagat acgactgtaa aatacgtatc tgcagtcaat gattttccag gttcttataa
    15241 accagaggga agtggtagtc ttcctaaaaa agaagataat aaagaatatt ctttaaagga
    15301 tttaattacg aaagtatcaa aagaatctga taatgtagct cataatctat tgggatatta
    15361 catttcaaac caatctgatg ccacattcaa atccaaaatg tctgccatta tgggagatga
    15421 ttgggatcca aaagaaaaat tgatttcttc taagatggcc gggaagttta tggaagctat
    15481 ttataatcaa aatggatttg tgctagagtc tttgactaaa acagattttg atagtcagcg
    15541 aattgccaaa ggtgtttctg ttaaagtagc tcataaaatt ggagatgcgg atgaatttaa
    15601 gcatgatacg ggtgttgtct atgcagattc tccatttatt ctttctattt tcactaagaa
    15661 ttctgattat gatacgattt ctaagatagc caaggatgtt tatgaggttc taaaatgagg
    15721 gaacaagatt ttttaaatca ttttctcaag aagggatatt tcaaaaagca tgctaaggcg
    15781 gttctagctc tttctggtgg attagattct atgtttctat ttaaggtatt gtctacttat
    15841 caaaaagagt tagagattga attgattctg gctcatgtga atcataagca gagaattgaa
    15901 tcagattggg aagaaaagga attaaggaag ttggctgctg aagcagaact tcctatttat
    15961 atcagcaatt tttcaggaga attttcagaa gcgcgtgcac gaaattttcg ttatgatttt
    16021 tttcaagagg tcatgaaaaa gacaggtgcg acagctttag tcactgccca ccatgctgat
    16081 gatcaggtgg aaacgatttt gatgcgcttg attcgaggaa ctcgcttgcg ctatctatca
    16141 ggaattaagg agaagcaagt agtcggagag atagaaatca ttcgtccctt cttgcatttt
    16201 cagaaaaaag actttccatc aatttttcac tttgaagata catcaaatca ggagaatcat
    16261 tattttcgaa atcgtattcg aaactcttac ttaccagaat tggaaaaaga aaatcctcga
    16321 tttagggatg caatcttagg catcggcaat gaaattttag attatgattt ggcaatagct
    16381 gaattatcta acaatattga tgtggaaaat ttacagcagt tattttctta ctctgagtct
    16441 acacaaagag ttttacttca aacttatctg aatcgttttc cagatttgaa tcttacaaaa
    16501 gctcagtttg ctgaagttca gcagatttta aaatctaaaa gccagtatcg tcatccgatt
    16561 aaaaatggct atgaattgat aaaagagtac caacagtttc agatttgtaa aatcagtccg
    16621 caggctgatg aaaaggaaga tgaacttgtg ttacactatc aaaatcaggt agcttatcaa
    16681 ggatatttat tttcttttgg acttccatta gaaggtgaat taattcaaca aatacctgtt
    16741 tcacgtgaaa catccataca cattcgtcat cgaaaaacag gagatgtttt gattcaaaat
    16801 gggcatagaa aaaaactcag acgtttattt attgatttga aaatccctat ggaaaagaga
    16861 aactctgctc ttattattga gcaatttggt gaaattgtct caattttggg aattgcgacc
    16921 aataatttga gtaaaaaaac gaaaaatgat ataatgaaca ctgtacttta tatagaaaaa
    16981 atagataggt aaaaaatgtt agaaaacgat attaaaaaag tcctcgtttc acacgatgaa
    17041 attacagaag cagctaaaaa actaggtgct caattaacta aagactatgc aggaaaaaat
    17101 ccaatcttag ttgggatttt aaaaggatct attcctttta tggctgaatt ggtcaaacat
    17161 attgatacac atattgaaat ggacttcatg atggtttcta gctaccatgg tggaacagca
    17221 agtagtggtg ttatcaatat taaacaagat gtgactcaag atatcaaagg aagacatgtt
    17281 ctatttgtag aagatatcat tgatacaggt caaactttga agaatttgcg agatatgttt
    17341 aaagaaagag aagcagcttc tgttaaaatt gcaaccttgt tggataaacc agaaggacgt
    17401 gttgtagaaa ttgaggcaga ctatacctgc tttactatcc caaatgagtt tgtagtaggt
    17461 tatggtttag actacaaaga aaattatcgt aatcttcctt atattggagt attgaaagag
    17521 gaagtgtatt caaattagaa agaataatct ttaatgaaaa aacaaaataa tggtttaatt
    17581 aaaaatcctt ttctatggtt attatttatc tttttccttg tgacaggatt ccagtatttc
    17641 tattctggga ataactcagg aggaagtcag caaatcaact atactgagtt ggtacaagaa
    17701 attaccgatg gtaatgtaaa agaattaact taccaaccaa atggtagtgt tatcgaagtt
    17761 tctggtgtct ataaaaatcc taaaacaagt aaagaaggaa caggtattca gtttttcacg
    17821 ccatctgtta ctaaggtaga gaaatttacc agcactattc ttcctgcaga tactaccgta
    17881 tcagaattgc aaaaacttgc tactgaccat aaagcagaag taactgttaa gcatgaaagt
    17941 tcaagtggta tatggattaa tctactcgta tccattgtgc catttggaat tctattcttc
    18001 ttcctattct ctatgatggg aaatatggga ggaggcaatg gccgtaatcc aatgagtttt
    18061 ggacgtagta aggctaaagc agcaaataaa gaagatatta aagtaagatt ttcagatgtt
    18121 gctggagctg aggaagaaaa acaagaacta gttgaagttg ttgagttctt aaaagatcca
    18181 aaacgattca caaaacttgg agcccgtatt ccagcaggtg ttcttttgga gggacctccg
    18241 gggacaggta agactttgct tgctaaggca gtcgctggag aagcaggtgt tccattcttt
    18301 agtatctcag gttctgactt tgtagaaatg tttgtcggag ttggagctag tcgtgttcgc
    18361 tctctttttg aggatgccaa aaaagcagca ccagctatca tctttatcga tgaaattgat
    18421 gctgttggac gtcaacgtgg agttggtctc ggcggaggta atgacgaacg tgaacaaacc
    18481 ttgaaccaac ttttgattga gatggatggt tttgagggaa atgaagggat tatcgtcatc
    18541 gctgcgacaa accgttcaga tgtacttgat cctgcccttt tgcgtccagg acgttttgat
    18601 agaaaagtat tggttggccg tcctgatgtt aaaggtcgtg aagcaatctt gaaagttcac
    18661 gctaagaaca agcctttagc agaagatgtt gatttgaaat tagtggctca acaaactcca
    18721 ggctttgttg gtgctgattt agagaatgtc ttgaatgaag cagctttagt tgctgctcgt
    18781 cgcaataaat cgataattga tgcttcagat attgatgaag cagaagatag agttattgct
    18841 ggaccttcta agaaagataa gacagtttca caaaaagaac gagaattggt tgcttaccat
    18901 gaggcaggac ataccattgt tggtctagtc ttgtcgaatg ctcgcgttgt ccataaggtt
    18961 acaattgtac cacgcggccg tgcaggcgga tacatgattg cacttcctaa agaggatcaa
    19021 atgcttctat ctaaagaaga tatgaaagag caattggctg gcttaatggg tggacgtgta
    19081 gctgaagaaa ttatctttaa tgtccaaact acaggagctt caaacgactt tgaacaagcg
    19141 acacaaatgg cacgtgcaat ggttacagag tacggtatga gtgaaaaact tggcccagta
    19201 caatatgaag gaaaccatgc tatgtttggt gcacagaatc ctcaaaaatc aatttcagaa
    19261 caaacagctt atgaaattga tgaagaggtt cgttcattat taaatgaggc acgaaataaa
    19321 gctgctgaaa ttattcagtc aaatcgtgaa actcacaagt taattgcaga agcattattg
    19381 aaatacgaaa cattggatag tacacaaatt aaagctcttt acgaaacagg aaagatgcct
    19441 gaagcagtag aagaggaatc tcatgcacta tcctatgatg aagtaaagtc aaaaatgaat
    19501 gacgaaa
//
LOCUS       DAVKEV010000039        19046 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVKEV010000039 DAVKEV010000000
VERSION     DAVKEV010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19046
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.039"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     regulatory      25..123
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            207..998
                     /gene="thiD"
                     /locus_tag="VWZ68_001592"
     CDS             207..998
                     /gene="thiD"
                     /locus_tag="VWZ68_001592"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU9372598.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQAKDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(1207..1839)
                     /locus_tag="VWZ68_001593"
     CDS             complement(1207..1839)
                     /locus_tag="VWZ68_001593"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU9372599.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(1832..2635)
                     /locus_tag="VWZ68_001594"
     CDS             complement(1832..2635)
                     /locus_tag="VWZ68_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU9372600.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLNYRPTVIKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSKNQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEAYE"
     gene            complement(2635..3159)
                     /gene="thiW"
                     /locus_tag="VWZ68_001595"
     CDS             complement(2635..3159)
                     /gene="thiW"
                     /locus_tag="VWZ68_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEU9372601.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            complement(3164..3856)
                     /gene="tenA"
                     /locus_tag="VWZ68_001596"
     CDS             complement(3164..3856)
                     /gene="tenA"
                     /locus_tag="VWZ68_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEU9372602.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKEMEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(3867..4517)
                     /locus_tag="VWZ68_001597"
     CDS             complement(3867..4517)
                     /locus_tag="VWZ68_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEU9372603.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(4519..5904)
                     /locus_tag="VWZ68_001598"
     CDS             complement(4519..5904)
                     /locus_tag="VWZ68_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9372604.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(5905..6465)
                     /locus_tag="VWZ68_001599"
     CDS             complement(5905..6465)
                     /locus_tag="VWZ68_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9372605.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(6727..6815)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(7024..7653)
                     /locus_tag="VWZ68_001600"
     CDS             complement(7024..7653)
                     /locus_tag="VWZ68_001600"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU9372606.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGAITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(7655..8437)
                     /gene="thiM"
                     /locus_tag="VWZ68_001601"
     CDS             complement(7655..8437)
                     /gene="thiM"
                     /locus_tag="VWZ68_001601"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU9372607.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEIAEKRPNGHLPGTFKAEFINALYEITDEDVKEFKRVK"
     gene            8528..8614
                     /locus_tag="VWZ68_001602"
                     /pseudo
     CDS             8528..8614
                     /locus_tag="VWZ68_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(8764..9432)
                     /locus_tag="VWZ68_001603"
     CDS             complement(8764..9432)
                     /locus_tag="VWZ68_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEU9372608.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYNV"
     regulatory      complement(9647..9735)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(9989..11125)
                     /gene="lctO"
                     /locus_tag="VWZ68_001604"
     CDS             complement(9989..11125)
                     /gene="lctO"
                     /locus_tag="VWZ68_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEU9372609.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(11750..13240)
                     /gene="lysS"
                     /locus_tag="VWZ68_001605"
     CDS             complement(11750..13240)
                     /gene="lysS"
                     /locus_tag="VWZ68_001605"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEU9372610.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINKPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(13368..13514)
                     /locus_tag="VWZ68_001606"
     CDS             complement(13368..13514)
                     /locus_tag="VWZ68_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEU9372611.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            13547..14464
                     /locus_tag="VWZ68_001607"
     CDS             13547..14464
                     /locus_tag="VWZ68_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275026.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEU9372612.1"
                     /translation="MYIAVWGSLGSFLLGLIVSIIRHYRIPVLAQVATAYIELSRNTP
                     LLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSAMQDSGIQVLFQGNNLLRILQGL
                     GVTIGISILSVLLSMMFGTVMGIIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFG
                     LARNFNINISGETSVIIVFTLWGTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYY
                     HIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTTSFW
                     IYGTILILYFAVCYPISKLSTHLEKHWRN"
     gene            14465..15223
                     /locus_tag="VWZ68_001608"
                     /pseudo
     CDS             14465..15223
                     /locus_tag="VWZ68_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            15235..16095
                     /locus_tag="VWZ68_001609"
     CDS             15235..16095
                     /locus_tag="VWZ68_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9372613.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHPTYGDAAK
                     ADDLVVEGGH"
     gene            complement(16175..16822)
                     /locus_tag="VWZ68_001610"
     CDS             complement(16175..16822)
                     /locus_tag="VWZ68_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9372614.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKPGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(16819..17517)
                     /locus_tag="VWZ68_001611"
     CDS             complement(16819..17517)
                     /locus_tag="VWZ68_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372615.1"
                     /translation="MGKLSSYMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(17527..18279)
                     /locus_tag="VWZ68_001612"
     CDS             complement(17527..18279)
                     /locus_tag="VWZ68_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372616.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(18279..19043)
                     /locus_tag="VWZ68_001613"
     CDS             complement(18279..19043)
                     /locus_tag="VWZ68_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372617.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
BASE COUNT         6015 a         4057 c         3392 g         5582 t
ORIGIN      
        1 tatgctatac taaagaaaaa agaaaacaac cactaggggt gcgtaaagct gagattaacg
       61 actgttagat ccctctgact caatctaggt aatgctagct gatggaagtg gaaatgataa
      121 tggggactag cagtcttcta ttgcctttct aaaacagact agcttgttct taagaataca
      181 aacttcagtt ggttgggagg ttttagatga cttatttacc cgttgctttg accattgcag
      241 ggactgaccc tagtggtggt gctggcatta tggcagattt aaagtcattc caagcgaaag
      301 atgtctatgg aatggctgtt gtaaccagtc ttgtcgctca aaataccaga ggtgttcagc
      361 taatcgagca cgtttctcct caaatgttga aagcccaatt ggagagtgtc ttttctgata
      421 ttccacctca ggctgtaaaa actggaatgt tggctactac tgaaatcatg gaaatcatcc
      481 aaccctatct taaaaaactg gattgtccct atgtccttga tcctgttatg gttgctacaa
      541 gtggagatgc cttgattgac tcaaatgcta gagactatct caaaacaaac ttactacctc
      601 tagcaactat tattacgcca aatcttcctg aagcagaaga gattgttggt ttttcaatcc
      661 atgaccccga agacatgcag cgtgctggtc gcctgatttt aaaagaattt ggtcctcagt
      721 ctgtggttat caaaggcgga catctcaaag gtggtgctaa agatttcctc tttaccaaga
      781 atgaacaatt tgtctgggaa agcccacgaa ttcaaacctg tcacacccat ggtactggat
      841 gtacctttgc tgcagtgatt actgctgaac tagccaaggg caagagtctt taccaggcag
      901 ttgataaggc caaggccttt atcacaaaag ctattcaaga tgcccctcaa ctcggtcatg
      961 gttctggtcc agtcaaccat acaactttta aagattaaga aaaaaactct ctagttccca
     1021 ctttaaggga attagagagt ttttataccc ttcgaaaatc tcttcaaact acgtcagctt
     1081 ccatctgcaa cctcaaaaca ctgttttgag ctgacttcgt cagtcttatc taaaacctca
     1141 aggcagtact ttgagcaacc tgcgactagc tttctagttt actctttgat tttcattgag
     1201 tattaattag gaaagaatgt catgcaactt tgttaaaaag gcttgcgttt ttgcctcaat
     1261 atcttctgct tgcatcaaat cacgtacaac agctacacca gctatgccag tgcccataag
     1321 ctgatcaata ttctccgaag tcaagccgcc aatagcaact attggaatgg caaccgtttg
     1381 gcaaattgtt ttcaaggttg aaatcagggt gatgggtgca ttttccttgg tggttgtcgg
     1441 aaaaatggct cctgtcccca agtaatctgc acctgatttc tccgcttcca gagctctttt
     1501 aaccgtttta gcggtgacac cgaggatttt ttcaggaccc aagacttgtc gggcaaccga
     1561 aactgggagt tcgtcatctc caatatgcag accagcagca tcaaccgcaa gacaaacatc
     1621 caaccgatca tcgattatca agggtacctg ataggcatct gttatttcct tgacttgttt
     1681 tgccagttga taatattgat tggttgtgag atttttttct cgcaattgga ctatggtaac
     1741 ccctgaacgg caggccgtct caacttttgc aagaaagctt tccacggaat cttgatagcg
     1801 attggttacc agatatagtc taagtgcttc tctattcata agcctctcct ttgatggtat
     1861 ctagccaatt ttcatctctt cttaggagcg aaagctgatt gagtacttgg taacgaaatt
     1921 cttccaatcc cattccttga acaactattt tctcagcagc gatattgaga taagagactg
     1981 ctaagcaaga agcttcaaaa ccagtctttc cttggctgag aaaaacggct gttaaggctc
     2041 caaccaaatc tcctgtccct gttatccagt ctaattcagt acagccattc tccagtacag
     2101 cgacctgatt tttcgaaacg atgaggtcct tggggccagt aactaagaat gacataccag
     2161 gataggtctg acaccagtct ttcaagactt gaagcaaatc ctccgtttct tgatctttag
     2221 cactcgcatc gaccccaacg ccgtggtgct ttaagccaac aagacttcga atttctgaca
     2281 tgtttccttt aatgaccgta ggtctatagt ttaaaaggtc tttaactaag ctcttacgaa
     2341 tggatgaagt cgttacgcca accgcatcta ctaccatcgg gagagaagat tggtttgcat
     2401 acgaagctgc catgcggatt gctttttcct tctcagctga caaatgcccc aaattgatga
     2461 aaagagcctg actttgctta gtaaaatcaa gaacctcacg gggatcatct gccatgacag
     2521 gtttgcatcc cagagccaaa atcccatttg ccagcatctc acaagaaatc tcattggtca
     2581 tacagtgaat tagggaacta gagcctatag gaaagggatt tgtaaattcc tgcatcagtc
     2641 tatcctttca ctaaagaaat atccctgcac ttttttaaag aattcctgct tgattaaaaa
     2701 tcgaaaggca ataaaggaaa tcgctgtacc aatcaaggtt gctccgaaaa atcgaggcgt
     2761 gtagataaac cagctaagct tagcagctga tcctgtaaag agtaccataa caggatagga
     2821 aacaatggaa ccaataatac ctgttcccac aatttctccc aaggcagaaa aataaaattt
     2881 tcgaccgtac ttataaaaga gacctgccag aagggctcca aaagtcgctc ctgtgagagc
     2941 taaaggcgga atcccttgag tcgtcatacg gataaaggct gtgactgtag ccatggccaa
     3001 ggcataaaca ggtcccatca tgattcccgc tagaatattg actacactgg acatcggtgc
     3061 cattccctca attcgaaaga taggtgtaag gactacatca agggcaatca tcatagataa
     3121 aatggtcaat ttgtgaactt gtagttggtg ctttctcatg tttctattct tctccttttt
     3181 ctaaagactg taaatcgctc ttccatgtct ggtgttggta agccatctcc caaaacttgg
     3241 cttccatatg aacactgatg tggaaggcat ctagcatttt ttgcttatct gtctcatcac
     3301 tttctcgata gagctgattg accagtgctc cctcctctct gatctgttgc tctaactcat
     3361 ccgtaatata agtttcaatc cattgttgat agagaggatt tggtgatggt ttaagattaa
     3421 gtgatttgcc tatatcatgg tataaccaag gacaaggaag caagcttgca aaagctatgg
     3481 ctaagttcgg ttctgcaaat tgcctataaa tatgagaaat gtaatgataa caggttggag
     3541 caattggatg ttgctccatt tcctggtcgc tgatttccat ttccttgaaa aattgttggc
     3601 gaataaataa ctcaccctcc actaaaccct gagcattttg tttcaagagt cttttcatct
     3661 cttggtttga agtcttatca gccaaaagat gatagatttc tgagaaggcc ttcagatagt
     3721 aggcatcctg aatcaggtaa tagcggaaaa tggcaggttc taaattcccc tcttgtaatt
     3781 gtaaaataaa gggatgatga aaggaagcct gccaagcttt cttggataat tccatcgcaa
     3841 tatctgtaaa ttccataata actcctttat aaaaatagac tggtttgaag caataaaaag
     3901 aaaagcaggt agattaattt tgttttttta ggaatataaa aagtccgata gctattcttc
     3961 aactgtgcat gttcgtcata tccatgagca gacagagctc tcaggtaaag atggcgccac
     4021 ctaaagactg tcatcagaac cttactgtaa atcaagggcg accaaaaatg cagttcttga
     4081 ccacgtaata ggcaagcttc tttgagggac ttgatttctt gctgaatgag aggaaaggaa
     4141 ttgaatacca caatcaaggc ataggaccaa gagcgtgata gccccttttg agccaagtac
     4201 aagagaagct cttttagtga aatagaggaa acaaagacaa ggccgataca aactgtcaca
     4261 aaggccctcg ttccaagcat gactgcctgt gaagcatctc cgtgtaactg aactgcccag
     4321 tagttggcaa aagatggtaa aatggcaagt atgatcatcc aagctaacat tttaaatcga
     4381 cggtaataga gcataaagag aatacaaaat gcgactaccg aaagattcag agcaatcgaa
     4441 ggaatgaaag atgtttccaa ggataaaatc agcaagaaga gactgataat cggtgtctgg
     4501 gttgctactt tgaccatact atctcacctc cccttgggta ttgctactct gagatgtaag
     4561 tggtttggta atggtcactt ctttcacatg ccgaagaccc tgactagtca tctcaatcca
     4621 ataatcaacc acagaaatca aagggtctaa acgatgacta atgagcagaa aacttcttcc
     4681 ttgattcctc tcctccacaa tccacttgca aaaataatgg caggctctat catccaaacc
     4741 tgcaaaaggt tcatctagca agatcacgga agccttactg gtcaagatgg tcaagagctg
     4801 aagaattttt tgctgaccac cacttaattg atagggactc ttatcgactg cctgctccaa
     4861 atcaaaatat cgtaaagctt gaaaaatccg ctgatttctt tcagaatcag gtccatctaa
     4921 ttgaagctcc tctcgcagac tgactcggat aaactgcttc tcagcttcct gaacaacacc
     4981 agtcagatca cgatacaaac tctttttctt tttcaggact gtccccttcc atgcaatgcg
     5041 ccccttatac ttttgaaatt gaagaataga gcgaaagagg gttgatttcc cgacaccatt
     5101 gtcacccagg atacaggaaa tcccttgata gaatgtgaaa tcagcaattg aaaagagggg
     5161 gcgattacca agctcaccag tcacacggtt catatggaat agttccgggc tagaagcaac
     5221 ttcctttgaa gcaacctgtg tcatctcata ggaagggatt tgaaacactt cccttagttt
     5281 tccgtctctt agctcaacca tatggtcgat ataggcttta tagtcagata aatcatggtc
     5341 gcacaaaata actgtcttcc catcaagagc caactctttt agaatctcca atatctcgat
     5401 tctgctcttg cggtcaatag aagcgaaggg ctcatccaag agatagaccc taggattcat
     5461 ggcaaagagg acagccagcg ctgctttttg cttttcccca cctgataggt gatgaatggg
     5521 acggtgtaag attgcctcgc aacgacattg ctggacaacc tctgctattt tagaatcaat
     5581 ttcctgaagg tgatagccga tattctccaa ggtgaaaatc agctcctcaa acaagttctc
     5641 catggtaaat tgatgattgg gattttgaaa gagaatgcca accttctgga cacgtgcgat
     5701 gatagaaagc tgactgacct cgctcccatc tatcaggact tgaccactat agggaagaga
     5761 actgacttgg gcaatgactt gaaaaaggct ggattttcct gaaccactgc tcccaactaa
     5821 caaggtaaag gcttgcgcat gaaaagtaaa atcaaacggc tcagagaaga ttggggactg
     5881 aatcgctcgt agttccagac ccatctatgc ttttcctcca gttgcaaact gatgatagag
     5941 tttgacaatg gcacgaacca agatggtaca gaagaaataa acagaaataa aacgtaccac
     6001 aagtaaggaa aggacaaacg gaagggaaaa ggcgtagtaa cctaacttaa tgtattcata
     6061 gacaaagcta acaagcgtaa tcccaatact attagcagtt agagagagcc aactttcata
     6121 gcgattctta gttacgataa aaccaaattc acttcccaaa ccttgaacca agccagacaa
     6181 aagagctcct agaccaaatt ggctaccata aaggacttca gcaagcgcag ctagcacttc
     6241 tccaatcgtt gcacttccga ctctcggaac aaagatggca gcaatgggcg cagccataca
     6301 ccagagaccg aagaggattt cattggcaaa ggcctgcaaa ccaagaggtg ttaagagtag
     6361 actgagaata ttatacacat atcctgaacc aacgaaaacc ccaccaaaaa agatagacaa
     6421 gaaagcaagc aagataacat cttttaactg ccattttttc aacataaaaa actccttttt
     6481 taaaagaaaa gtggggcact caagaagacc gacctaaata ctttgtatag cagattgaat
     6541 ttagaacagt acacaggaat gctaaaatat ttctagaaat taatttgaat tttctaattg
     6601 atttgttcgc atcttatttc aatctactat atcatcttca tccagtttcg taaaagaaaa
     6661 aactctaatt acagatacga attagagttc agcttacaag attagacagt tcttttcgac
     6721 atacgaaaaa aacatttcac atttcccttc gccagtctta actgtatcag gttcaatggg
     6781 tatcatctca gcctaaagca ccccaaatgc ctttattatt taattatgtg attattataa
     6841 cacacatttt atactagttc aagaaattga actggaaata cagccttgca ctcacaaaga
     6901 cagcagatct ttcttttgca aaaaacaaat gacctgtttg atgaattagc cattcaagct
     6961 gaatctagac atagcttttt aaaaaaggaa aatcctactt acttagaatc caaggataga
     7021 tatctattgt tcactcattt cccgaacagt tttttctata ttttttgcat acgatattgc
     7081 cgaaatgatt gaaacgccgt caacattggt ctttataatg tctttaatat gtttcgtctg
     7141 tatcccacca attgcaacta aaggcatttg tggcaatagt tttctcatca attcaagacc
     7201 ttcataacct atagcaccac cagcatcatc ttttgactgg gtatcaaata caggcccaac
     7261 acctacataa tctacatatt caacttttga ttgttgaaat tcttcttcgt ttcttataga
     7321 aagaccaatt attttatctg gcatcaattt tctaatttca tcaacaccaa tatcatcttg
     7381 acctacatgt acgccatcgg cgtcaatttc cattgctaaa tctatatcgt cattaacgat
     7441 aaatggaaca ttgtattttt tacaaagttc tttaatttgg atagctagct caagtttttc
     7501 taagccttct aaagcaccct cacctttttc tcgaaattga aataaggtta tagcaccttt
     7561 taaggcttcc tcaacgactg tatatagatt ttttccttgg caagtagtcg ttccacaaat
     7621 aaaatatagt tttagtaatt ctttatgaaa catcttactt cactcttttg aattccttta
     7681 catcttcatc tgtaatctcg tataaggcat ttataaattc agctttaaat gttccaggaa
     7741 gatgtccatt gggacgtttt tctgctattt ctccagcgat attgtaaacc aacattgctg
     7801 tttctaatga tttcaattct tgaccttttt ctagtccgat aaagcttgct actacagctc
     7861 ctaataagca tcctgtccca atgactttcg gcatcatagc actaccatta tgaatcgtta
     7921 ccacttctcc attaacagca atggcatcca cttcacctgt tactactatt ggaatattga
     7981 acttctcatt tgctgctaga gcaatttcgt caatattatc tacgcccgca ctatctactc
     8041 ctttagatgc cacatctatt cctactaaag aggcaatctc gccagcattt cctctaatcg
     8101 ctgctagttt ataattgttg attagatcat ccgctacttt ttttctatat tctcctgctc
     8161 cacaggctac aggatctaaa actgctggga cattatattt ctccgcaatt ttcagagcag
     8221 cttggtataa tttccaattt tcatctgtca atgttcctat gtttattaat aaaccaccag
     8281 catactttaa caaatcctct aaatctgctg gaaactcact catggctggt gaggcgccca
     8341 gtgctactaa tccatttgct gtgaaatttt ttactacatc attggttata caaatgacca
     8401 atggtgcttt ttcttttaat aattttaaac ttgtcatatt gaaatccttc cttttcactt
     8461 tatacgatct actgatttcg atttatatct atctttcgtt aagaaatttt tttcatttac
     8521 attgaatgat ttatactcaa tgaaaatcaa agagcaaact aggaagctaa ccgcaggttg
     8581 ctcaaaacac tgctttgaac ctgtagataa gactgacgaa gtcagctcaa aacactgttt
     8641 tgaggttgtg gatagaactg acgaagtcag taaccatacc tacggcaagg tgaaactgac
     8701 gttgtttgaa gagattttcg aagagtctta cctcatcaaa tttgtaaata tcatgagcct
     8761 tctctagaca ttgtaaccaa tatcaaaaaa agctaattct aaagcgactg cttgattcca
     8821 gcgttgctga agttctgtca aatcttctcg atttttaccg acacgattga gttcgtcaac
     8881 cagaaattga acccactctg caaagaaagg acctctgtgg agattgatcc attccgaatg
     8941 aatatagact tcaggtagag ccaaatcttt agaaccccag tctaaataga gaccttctgc
     9001 aatgaccagc ataaccaaaa gatgggcata gtctgatgaa gccactgccg aatacattag
     9061 atcctgaaag gcttttgtta cagggtgcaa agtcacttct agatagtcat tctctgctac
     9121 ttttaactct ttaaaagcct tttggaaata accatcttca tctgcttcaa gaaagcctag
     9181 ttgcttggca aaacgaagct tggattcaag tttatctgcg tgagctacgc aggcacccag
     9241 catggataag aaggcatcaa agaagtgata atcttgaatc agatagtcct ttaagacctt
     9301 attctcaatt gtccccgcaa aaagttcctt aacaaaacga tgattgattg cagcctgcca
     9361 atccttctga ctgcttttta ataattctcc aacagtcaaa cctggctgaa atgcatagtc
     9421 ttgtgtttcc atatttactt ctcctctctt tacttgttag taattaataa aacaccaaga
     9481 aatatcaagc aaaatcgtaa ttccacttga tccttttaaa gcacatcgag agcatttgca
     9541 gagagctaac taaacaagcc tatccagttt atataaacaa aaaactccaa ttacaatcaa
     9601 gaattagagt tgacttacaa gattagaccg ttcatttcac catacgaaaa aactgttcac
     9661 atttcccttc gccagtctta actgtatcag gttcaatggg tattatctca gcctaaagca
     9721 ccccaaatgt ctctattatt taattactga accagtatag caaaaaatga aagccctagc
     9781 aagatatttg accgaaaaat atctttatat ataatatatt gaaactagaa tagtacacct
     9841 ctacttctaa aacattgtta gaaatcgatt taactgtcct gattaatttg tcctattctt
     9901 atttcatttt attatagttt tcgatagcga tttattcttc caatacacga agaaaaacct
     9961 ccacattcag tggaggcaat ctgttttatc aatacaattt taagtcacga gggtcaactg
    10021 ggaaggttgg gttgtatgga ttgtgacgga gcttaaagtg tttgacatct tcaatggtct
    10081 gagctccaga caattgcata actgtcttca attccgcatt caagtgttca aagacttgac
    10141 gcacaccgac actaccaccg agagccaagc cataaataac agggcgacca atagctacca
    10201 agtctgctcc tgaagccaag gctttaaaga cgtgttgacc acgacgaaca ccagagtcaa
    10261 agacaatcgg cacacgtcta tcaactgctt ctgccacttc ttgaagcgag tcaaaggcag
    10321 ctggtccacc gtcgatttga cgaccaccgt ggttggttac ccagatacca gaagctcctg
    10381 cagcaagtga acgttcaacg tcctcacggc attgtggtcc cttgacatac acaggaagac
    10441 cagagtattc agcgataaat tctacatcgc gtggagacaa gcgttgttta gctgatttgt
    10501 aaacaaagtc cattgattta ccagcacctt ctggcaggta ttcttcaaca atcggcatgc
    10561 caactgggaa gacaaaacca ttacgcttat ccacttcacg attcccccct acagtagcat
    10621 ctgccgtcaa gacaatcgct ttataacctt cagccttcac acggtccatg atgtggcggt
    10681 tgataccgtc atccttacta aagtaaaatt gaaaccaatg aggtgtccct tgaagggctt
    10741 cagaaatctc tggaaggtca acagtagagt aagaactggt tgtataaaga gaaccaaact
    10801 catgcacacc acgcgcagtc gccacttccc cctgttcatt cgctaattta tgggccgcaa
    10861 caggcgccat aatgattggt gaagatagtt tttcacctgc aaattcaatc tctgtacttg
    10921 gattttcaac atcgcaaagt gtatgaggaa cgatgagttt gtggttaaag gcgcggatat
    10981 tctctcttaa agtgaaagta tcttccgccc cactagcgat atagccaaat gctgctttag
    11041 gaataacttg ttgcgccatt ggctccaaat cataggtatt gatgaagtct acatgacctt
    11101 ctgcattgct tgttttgtat gacataaaat gccctccttg attaagtaag cgtttgcttt
    11161 ttactacaca actataataa ctcttttttc aatcattttc aagagttttg cttaaaaacc
    11221 atcttatttt ttcatacaat atactagccc tactttcctt aaactctaaa ctttagtcta
    11281 tattaagtga atcgttgaga ttttttgctg ccaggcattt gaactacttt tttatttgcg
    11341 gattctatct actaatacta taaaaaaaca agtgaataag acaccagaac atcctctaat
    11401 aggacctatg gacttatatc agtcccatat atactgttta agcaagatac tatcctagtt
    11461 gacgctaact tcctatccca cttattaatt ttttatttat agtgaatctg aacaaatcaa
    11521 ttgggaaatc caagtcaatt tctagtactt tttgaacagt ttcagcgtac tatcgtaaaa
    11581 tgaaataaaa catgcacaaa ttgattaggg aatttaaacc aatttctaac agtgtcttag
    11641 aaatcaaagt gtactatttc aacttcaata tactacactt cattttctcc ttaaattcag
    11701 tctctttttg aatcaaaaaa tcccctggta agagccagag ggtaagaatt tatttcattg
    11761 ttgggaagag caatacatca cggatagttg ttgtatcagt gaggagcatg cagagacggt
    11821 cgataccgat tcccaaacca cctgttggtg gcataccgta ttcaagagcc tcgatgtagt
    11881 catagtcgat gcctgtcgct tcatcatcac caagttcttt agctttagct tgggcttcaa
    11941 aacggctaag ttgatcgatt gggtcgttca actcagtaaa ggcattaccg tactccttag
    12001 tcatgataaa gagctcgaaa cggtcagtaa agcgttggtc ttcaggattt ttcttagcga
    12061 gtggagatac agctactgga tgtccataga caaaggttgg ttggattaaa gtttcttcga
    12121 caaactcttc aaagaaggca ttgatgatgt gaccaacctc agtgtagtgt ttctcaactg
    12181 gaactttctt ctcagcagcg atagctttag cttcttccaa agtcatgtct tgccagaaat
    12241 cgacaccagt aatttctctg atagcatcca ccatatgaac acgcttaaat ggtttgttaa
    12301 tcttgatttc agtaccttgg tagttgactg ggccatcacc tttgactgat ttagcagcgt
    12361 gttggataat gccttccgtc aagtccatga tgtcttggaa atctgcataa gcttggtaaa
    12421 cttcgataga agtaaactca gggttatgag tagcgtccat tccttcgtta cggaagatac
    12481 ggccaatttc atagacacgt tccataccac ccacgataag gcgttttaag tgaagctcag
    12541 tcgcgatacg aagcaccatg tcaatgtttt gggcattgtg gtgggtgata aatggacggg
    12601 cagcagcacc accggcttca ttatgaagaa caggtgtttc cacttcaagg aatccttttt
    12661 ggtcaaggta acgacggatt tcagagatga tttttgaacg agtgacaaag cgttcaaagc
    12721 tttcacgatt agaaatcaag tcaaggtaac gtttacggta aattgtttca acgtctgtca
    12781 aaccatggaa tttctcagga agaggacgaa gagccttaga caagtgtgtg atgtgggttg
    12841 ccttgataga gagttctccc atatccgtac gcatcacttc accttcgaca ccaaggaagt
    12901 caccaaggtc tgcttttttg aagatttcgt agttttcttc accgacagca tccttacgaa
    12961 catagatctg aatctggcct tcgcggtctt gaaggtgggc aaaaccaact tttcctttac
    13021 cacgtttggt taccaagcgt cctgcgatag tagctgtttc gtttttatcg tgtaattgtt
    13081 ctttatcgag gttggcatat ttatctttta attcttgtga atttgcagta cgttcaaaac
    13141 gttttccgaa aggatcgatt ccttgttcgc ggagcgcagc cattttttca cggcgaacga
    13201 tctgctggtc atttagttct tccatatgtt ctgtagacat gggatcctcc tagttttact
    13261 caaaattgaa tacgatgagt cattttttgc gataccccca ttttatcata aataagcaag
    13321 aaattcacgg ataatcttta aaaactaaaa agaacctgac gctaaaatca ctggaaagaa
    13381 gtgaaagtat cttccgcccc actagcgata tagccaaatg ctgctttagg aataacttgt
    13441 tgcgccattg gctccaaatc ataggtattg atgaaatcta catgaccttc tgcattgctt
    13501 gttttgtatg acataaaatg ccctccttga taagtaagcg tttactttgt atattgcagt
    13561 ttggggaagt ttgggatcct ttctgctcgg tttaatcgtt agtatcatcc gacattatcg
    13621 aatccctgtt ttggcgcaag tagcgacagc ctacattgaa ttgtcacgta atacgcccct
    13681 tttgattcaa ctcttctttc tctacttcgg tcttccccga atcgggattg tcctatcttc
    13741 agaagtctgt gcaacgcttg ggcttgtctt tttaggaggc tccgccatgc aggattcggg
    13801 aatccaagta ctctttcaag gaaataacct cctgagaatc ttacagggat tgggcgttac
    13861 gattgggata tccatcctgt ctgtcctctt atccatgatg ttcggaacag tcatgggaat
    13921 catcatgacc tcccattcta gaatcatacg atttttaaca cgattgtatc tggaatttat
    13981 ccgtatcatg ccccagctgg tgctactctt catcgtttac tttggcttgg ctcgaaactt
    14041 taatatcaat atctcaggtg agacttcagt tattatcgtt tttaccctct ggggaacagc
    14101 tgaaatggga gacttggtac gtggagctat cacttctctc cctaaacatc agtttgaaag
    14161 tggacaggca ctcggcttga ctaatgttca actttactac cacatcatca tcccacaagt
    14221 cttgagaaga ctgctaccgc aggctatcaa tcttgtcact cggatgatta aaaccacttc
    14281 attagttgtt ttgattgggg ttgtggaagt gaccaaagtt ggacaacaaa tcatcgatag
    14341 caatcgcctg accatcccaa ctacttcatt ttggatttat ggaaccattc taatcttata
    14401 tttcgcagtt tgctacccta tttccaaact atccactcac ttagaaaaac attggagaaa
    14461 ctaaatgtct gaaactatct tagaaatcaa ggaactaaaa aaatccttcg gagacaatcc
    14521 catcctccaa ggactttctc tagaaatcaa aaaaggggaa gttgttgtca tcctagggcc
    14581 atctggttgt gggaaaagta ccctccttcg ttgcctcaac ggcttagaaa gtattcaagg
    14641 tggagatatt cttctggatg gtcagtctat cgttgaaaat aaaaaagatt ttcacctagt
    14701 tcgccaaaag attggcatgg tcttttaaag ttatgaactc tttccccatc tggatgtctt
    14761 acaaaacctc atcctaggcc ctatcaaaac tcaaggatgg gacaagaaag aagtaacgga
    14821 agaagctttg caattactag atcgtgtcgg tttgctggat aaacaacata gctttgcccg
    14881 tcaattatct ggtggacaga agcaacgtgt tgcaattgtc cgtgccctcc taatgcatcc
    14941 agaaatcatc ctttttgacg aggtgactgc ttcgctggat ccagaaatgg tgcgtgaggt
    15001 gctggaactt atcaatgatt tggcccaaga aggccgtacc atgattttag taacccacga
    15061 aatgcagttt gcccaagcca ttgctgaccg gattatcttc ctcgaccaag ggaaaatcgc
    15121 tgaagaagga acagctcaag ccttctttac caatccgcaa accaaacgag cccaggaatt
    15181 tttaaacgtc tttgacttta gccaattcgg ctcatatcta taaaggagat tcttatgaaa
    15241 ctattcaaac cactcttaac tgttttagca cttgcctttg cccttatctt tatcactgct
    15301 tgtagctcag gtggaaacgc tggttcatcc tctggaaaaa caactgccaa agctcgcact
    15361 atcgatgaaa tcaaaaaaag cggtgaactg cgaatcgccg tgtttggaga taaaaaaccg
    15421 tttggctacg ttgacaatga tggttcttac caaggctacg atattgaact agggaaccaa
    15481 ctagctcaag accttggtgt caaggttaaa tacatttcag tcgatgctgc caaccgtgcg
    15541 gaatacttga tttcaaacaa ggtagatatt actcttgcta actttacagt aactgacgaa
    15601 cgtaagaaac aagttgattt tgcccttcca tatatgaaag tttctctggg tgtcgtatca
    15661 cctaagactg gtctcattac agacgtcaaa caacttgaag gtaaaacctt aattgtcaca
    15721 aaaggaacga ctgctgagac ttattttgaa aagaatcatc cagaaatcaa actccaaaaa
    15781 tacgaccaat acagtgactc ttaccaagct cttcttgacg gacgtggaga tgccttttca
    15841 actgacaata cggaagttct agcttgggcg cttgaaaata aaggatttga agtaggaatt
    15901 acttccctcg gtgatcccga taccattgcg gcagcagttc aaaaaggcaa ccaagaattg
    15961 ctagacttca tcaataaaga tattgaaaaa ttaggcaagg aaaacttctt ccacaaggcc
    16021 tatgaaaaaa cacttcaccc aacctacggt gacgctgcta aagcagatga cctggttgtt
    16081 gaaggtggcc attaactctt aaaagggact ggattttaag ctccaatccc tttttaagat
    16141 tttacctata acatcctgag tctatctaag atgttcaatc tgaacacagt gtacatactt
    16201 tatcttctat tgcatatact ttatcacata agatacgaat atcctcttca ctatgactag
    16261 caatcaaaat tgttgtccct ttttcactag agagctttct aaacaatgtt ctcatatttt
    16321 ctacacttga tttatccaag gcattcatag gttcatctag taaaagaata gagggattct
    16381 ccataattgc ttgagcaatc cctagctttt tcctcatacc tagcgaataa gttttaactt
    16441 tctggtcttt ttgctcatat agaccaacta ttttcagtgt atcattgatt tcctgattac
    16501 caactactcc tcgtatgctt gccaaatatt gtaaattctt aaagccacta taataattta
    16561 taaaaccagg ttcttcaatc aaagctccca aattagctgg aatttttctc tcaggaacaa
    16621 tattttcccc attgattaac acttctccat aagacggact atataaacca gctattaatt
    16681 taaacaatac acttttccct gagccattcg caccagtgat tcctatgatt tcccctggtt
    16741 tacaactaaa gttaaggttt tgaaaaacac atgtcttttt taatttcaac tcaatatttt
    16801 ttaatatgat tatttcattc attctataaa cctcctcttt tgacgagtga aatagaaaat
    16861 acttttaaaa agaaagacta aaaatagcaa ctgaagaaat aaatctcgtc ctatatctcc
    16921 attccctcga ttcaaaatat aaaatagata attagttcga ttccctacaa atagaccacc
    16981 aaacacaatc atgagtaaaa agaaactaac gcaagcaaag ttcatttgta cattcgctcc
    17041 tagtgcgtat aacataaagc aaagcaagga tagcacacaa gcattcaaag aatcaactat
    17101 aaacaaaact cctatatccc agtttggtaa ctgtaacata aattgaatca ctagaacttt
    17161 taccatgatt aaaatgagtc cataaagaaa acaggtccaa atctgatacc taatccagag
    17221 cttaatagaa gaaaatcgaa tcacttccat aaagaaatcg gatgctcttc tacgatatac
    17281 aactgctaga aaaaatgtat gaataataaa ccaatgaagc aaccatatgg ataagactaa
    17341 aaaagagttt tgactcagat taggcccttt taaaatttct ataacaagtc tatcatttcc
    17401 ttctaaccaa taccataatc ctaaacaaat caatatccaa aaaagaacat aaccccaaaa
    17461 gtacttggta tagattatct gattcaacct ccacatgtaa ctacttaact ttcccatttc
    17521 caacttttac actctcctcc agtttctatg aacagaaaat acagtcaatg gaattatgat
    17581 agatagtaat gtaagccaat aaatcaatgc atacggattg gaatttacca tatactgaaa
    17641 aattggcaat aatccaatta tcccattgtc caactgataa atccagaata aggattctac
    17701 aaataaaaaa gtaaacagaa atactaagct catgtttgat tttttaaacc aagaaaaact
    17761 gctaatagta agtaaggata aaaagaaata gtatgctata taagagaaaa aaaatcctat
    17821 aaagaaacta gcattgtttg caatacttat accataaaat tctcttaaaa aatcaacctc
    17881 ctttatctcc aaagagaagc taaaaccatt actaaatgca attagaaaaa tcaataaaaa
    17941 taaagtcgcc gtccaaatcc ccgtactaag agctgctaat ttgaaactaa aactggtaaa
    18001 gtgcttaatt gatttcagac gaatgcgaca ctccaaccta ttaaaatagt tattcatcaa
    18061 ataaaaaaag aacaatatat atgtgaacgg aaagcaatat actccagtcg tcatatcttg
    18121 aagtaaaact aagatccatt ctaatacatt tggatggatt gaatattggc gacagcgcaa
    18181 taaatatact gtactagata aaacacagga tagcagtaat ataaaataaa ccaatactgc
    18241 taagaaatct tttttataaa attgaacaaa ttgtttcatt atacgtagtc ctctgaatgt
    18301 agaaaaaatg taccataaac aaccaaacaa ctaacaaata aaataaaagc aagatgccca
    18361 ctaactaagg aaagactgat atctttctga tatcccaaag ctaatgttgt cacaggttct
    18421 aagtaagata gccctaaaat agcccaaaaa ataccaccaa ccatcatata ggcaactggg
    18481 atgaaaatag ctcctatttt tttcttcact agcaaagcac tagctagtcc aaaaatagag
    18541 aacacagcgc cccaaactcc ataccagaga gtcgtcacaa gactatagag caactgatta
    18601 gaatcaaata attcttttaa ggcaccacta taatctccaa tataaatttc ctgataagga
    18661 gtcactaaaa gattaattcc taataataat aaatagggga gaaaaaagac tagaaaagaa
    18721 gaaataattg cagtactacc cacaatagct agatacctct ttttagaaat tcggcacaat
    18781 tgtgctgtta gaaaatgact ctcagcatcc tctattatct gactagaata gggcagtgta
    18841 cagataagtg cagctactag gctaatcggt gaaaatcctc gaatagaaga agcggcaaaa
    18901 aaaatcgata aaccttcaat tttataaata ccattgaaag caaggaaatt tcctaaactc
    18961 atgcaaagaa gggtcaaaaa taaagacata taaaatcgag gtgattgaac gactcgtaca
    19021 agattacaaa tgaaaaattc catcct
//
LOCUS       DAVKEV010000040        18809 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVKEV010000040 DAVKEV010000000
VERSION     DAVKEV010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18809
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.040"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..99
                     /locus_tag="VWZ68_001614"
     CDS             <1..99
                     /locus_tag="VWZ68_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU9372618.1"
                     /translation="EKTWAHIKKHLKKVLPSCHTFYEALLSCSCFN"
     gene            255..593
                     /locus_tag="VWZ68_001615"
     CDS             255..593
                     /locus_tag="VWZ68_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEU9372619.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHYQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            783..2219
                     /locus_tag="VWZ68_001616"
     CDS             783..2219
                     /locus_tag="VWZ68_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU9372620.1"
                     /translation="MTTFKDRFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITSGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPATCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            2271..2509
                     /locus_tag="VWZ68_001617"
                     /pseudo
     CDS             2271..2509
                     /locus_tag="VWZ68_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
     gene            2639..2953
                     /locus_tag="VWZ68_001618"
     CDS             2639..2953
                     /locus_tag="VWZ68_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEU9372621.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            3071..5050
                     /locus_tag="VWZ68_001619"
     CDS             3071..5050
                     /locus_tag="VWZ68_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU9372622.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            5060..5374
                     /locus_tag="VWZ68_001620"
     CDS             5060..5374
                     /locus_tag="VWZ68_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEU9372623.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            5405..5911
                     /locus_tag="VWZ68_001621"
     CDS             5405..5911
                     /locus_tag="VWZ68_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372624.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            5991..7337
                     /gene="celB"
                     /locus_tag="VWZ68_001622"
     CDS             5991..7337
                     /gene="celB"
                     /locus_tag="VWZ68_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEU9372625.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVIIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDVFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            7717..7893
                     /locus_tag="VWZ68_001623"
     CDS             7717..7893
                     /locus_tag="VWZ68_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372626.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            8294..10507
                     /locus_tag="VWZ68_001624"
     CDS             8294..10507
                     /locus_tag="VWZ68_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEU9372627.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSKTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAIPLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNKNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQVAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GILDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPMYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLAFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTI
                     PVFAKSGAIIPLVGSEIDMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELTLQGDSSIVPSNRRHRIHFKGTNVSIIELPNKNDTARFECKDNKTISLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(10729..11205)
                     /locus_tag="VWZ68_001625"
     CDS             complement(10729..11205)
                     /locus_tag="VWZ68_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEU9372628.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            11428..14507
                     /locus_tag="VWZ68_001626"
                     /pseudo
     CDS             11428..14507
                     /locus_tag="VWZ68_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
     gene            14860..15245
                     /gene="tnpA"
                     /locus_tag="VWZ68_001627"
                     /pseudo
     CDS             14860..15245
                     /gene="tnpA"
                     /locus_tag="VWZ68_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(15624..16253)
                     /locus_tag="VWZ68_001628"
     CDS             complement(15624..16253)
                     /locus_tag="VWZ68_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU9372629.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(16263..17264)
                     /locus_tag="VWZ68_001629"
     CDS             complement(16263..17264)
                     /locus_tag="VWZ68_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU9372630.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(17295..17936)
                     /locus_tag="VWZ68_001630"
     CDS             complement(17295..17936)
                     /locus_tag="VWZ68_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEU9372631.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(17955..18770)
                     /locus_tag="VWZ68_001631"
     CDS             complement(17955..18770)
                     /locus_tag="VWZ68_001631"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEU9372632.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
BASE COUNT         6077 a         2947 c         3903 g         5882 t
ORIGIN      
        1 gagaaaacat gggctcatat caaaaagcac ctcaaaaagg tattaccaag ttgccatacc
       61 ttttatgagg ctcttttgtc ttgttcttgt ttcaattgac tataaatcgc tataagaaaa
      121 aatcatttta ttggtataaa gaagtgattg aaagtaatgg caaaacgtta gataattagt
      181 tcataaaaaa caagtttaga tcctcatcta aacttgtttt tttaaaattg aaggatgatt
      241 ttggaggata taagatgaca ttgactattc atgtatatta taaaggtgat ggagatagtg
      301 caataaagtt tgcaagagaa atgcttgata gtggccttgt tgaagaaatt agaaatcaaa
      361 aaggtaactt gaaatacgaa tattttttac caattgaaaa agagggaact attctcctta
      421 ttgatcagtg gataaatcaa gaaactttag ataaacatta tcaatcaaag acaatgcaga
      481 aaatcttaga tttaagaaaa aaatatcact tgcagatgca agttgaacgt tatatagaag
      541 atgattctgg gatgccagaa agcgataagt cgtttataga cacagggaat tagaattatt
      601 gtgagagttt ttgtagtttg aaagtattga aaatcgtaaa gatatcatta cgagaataca
      661 agaagatatt gttctatttc cattaaaaat tacttctttc cttaacaata aggaaaaaga
      721 atacgttttc attttttggt ttgaggttta taataagagt atcaaagtca ggaggaaaaa
      781 agatgactac ttttaaagat agatttttat ggggtggtgc tgttgctgct catcaacttg
      841 aaggcggatg gcaagaaggt ggcaaaggaa ttagtgttgc tgatgttatg actgctggtc
      901 gtcatggagt agctcgtgaa attacttcgg gagttttaga gggtaaatat tatccaaatc
      961 atgaggcgat agatttttat catcgttata aagaagacat agcacttttt gctgaaatgg
     1021 gattcaagtg cttccgtacc tctattgcat ggacacgtat ctttccaaaa ggtgatgagt
     1081 tagagccgaa tgaagaagga ttacagtttt atgataatct ttttgatgaa tgcttaaaga
     1141 atggtattga acctgtcatc actctatctc attttgaaat gccttatcac ttagtgaccg
     1201 aatatggtgg ttggaaaaat aggaaattga ttgatttctt tgctcgtttt gcagaagtcg
     1261 tatttaaacg ttacaaagat aaggttaaat attggatgac tttcaatgaa atcaataatc
     1321 aagcgaatta tcaggaagat tttgcaccat ttactaactc aggtattgta tatgaggaag
     1381 gtgataatag agaagcaatt atgtatcaag cagcacatta cgaactagtt gcttctgcac
     1441 gagctgtaaa aattggtcat gagattaatc cagattttca aataggttgt atgattgcga
     1501 tgtgtccaat ttatccagct acttgcaatc ctaaggatat cttaatggca atgaaagcta
     1561 tgcagaagcg ttattatttt gctgatgtgc atgttttagg taaatatcct gagcatattt
     1621 tcaagtattg ggaacgaaaa ggtatttcag ttgattttac tgaccaggat aaagaagatt
     1681 tacttggtgg gactgtagat tacattggtt tcagttacta tatgtccttt gctatagact
     1741 ctcatcgtga aaataatcct tattttgatt atcttgaaac agaagattta gtgaaaaata
     1801 attatgttaa ggcttctgaa tgggagtggc aaattgatcc agaaggttta cgttatgcgt
     1861 taaattggtt tacagaccac tatcacttac cactctttat tgttgaaaat ggttttggag
     1921 ctatagatca agttgcagca gatggtatgg tacatgatga ttatagaatt gaatatctag
     1981 gtgcccatat tcgtgaaatg aaaaaggctg tagttgaaga tggtgttgat ttaatgggtt
     2041 atactccatg gggatgtatt gatttggttt cagctggtac cggtgaaatg cggaaacgtt
     2101 atggttttat ttatgtagat aaagatgaca atgggaaggg aagttataat cgttccccga
     2161 aaaaatcttt tggctggtat aaggaagtta tttcatctaa cggtgaatca gtagaatagt
     2221 ataaacaaac tgagattatt ctcagtttgt ttagcatatt gggatgacat atgattggaa
     2281 gtattgcagc aattttaaca acatttgctt tttaccacaa gtttttcgta tagttaagac
     2341 aaaggacaca ggatctattg ctctaggtat gtatgttatg caagttattg atattgcatt
     2401 gtggcttgct catggtattc gtataggaga cttgcctttg attttagcaa atagtgtttc
     2461 atttctactc tcaggaataa ttttatttta taaattgaag tataaataat ttttttccat
     2521 atcatttagg aaaatgaggg aattgtcatt ggaaacgctt tattttataa taaaaataga
     2581 taacagataa gtcaacttag cacagctttg attggattta agaaaaggag aaaatattat
     2641 ggcaaaagct ttaattattt gtgcagcagg aatgtcttca tcacttatgg cacagaaaac
     2701 aacagagttt ctaaaaggaa aagggaaaga tattgtagtt gatgctatta gtgctactga
     2761 aggagggaaa gctatcgcag cagcagcttt tgatttgtat cttgtcagcc ctcaaacaaa
     2821 aatgtacttt aagcaatttg aagaggctgg ttctaaagca ggaaaaccag ttgtacaaat
     2881 acctcctcaa gcctatattc ctattccaat gggaattgaa aaaatggcta atttgattct
     2941 tgagaatatt tgatgaacac atgaaatgtc aataaatatt taagttaaga taaattgttt
     3001 tgagtttgat ataaattgat ttaagtgtat aatatgcttc aatatatgaa aacatacgtt
     3061 ttaggaggga atgaatgtgt taaacattaa agagaaagat atccttcaat ttttaataaa
     3121 aaataaggaa cgttttgtta caagcaaaga actggcagaa tatttatcct gttcagatag
     3181 aactgtccgt aatgtactga aattaattga gaagacaatg attattcaag gagtccggtt
     3241 gatttcaaaa caaggtcaag ggtatcaaat attttttgag aatcaaggcg cttaccagga
     3301 gtttagacaa acttatgaac tggaagaaga ctatacgaaa actgcggttt caaaaggtga
     3361 tgatcgttta gtatttatct taaataaatt attatttgag caagttccag ttctttttga
     3421 tgatttagct gatgaacttt acgttagccg ttcaacatta tctcatgatt tcagaaagat
     3481 acgagtgatg ttatcagagt ataatttgtc cattgagagt agggcgaata aaggagttta
     3541 tgtctcaggc gaggaacgtg ataaacgacg ttttatcata aattatttcc tagagaatca
     3601 attttttaaa acaatacatt gctatgtaaa atttaacttt tttgatcaaa ctgttccatt
     3661 agaagaattt gctagaattg ttttggatga atgccaagag gccaacctaa aactatctga
     3721 ttttgtacta cagaacttag tagttcacat agcattgtct gtgattcgtt taaaatccgg
     3781 atttgaaata aaaaatatag actgtcagat gactgatgat gcaatagaga gaaaggttgc
     3841 ccaaagaatt ctttctaaag taagagaagt aacaaatcag gaatttccag ttcaggaaat
     3901 agactacatt actttgcatt tgttagctaa gagtcaacaa tgtcaaaaaa atcagaagaa
     3961 tatttctgaa gaagttttaa aaaaatcttt atttaaaaca tttcagaatt taggattaga
     4021 tgatatgtat aacttttctt cagatttcca actaattgaa ggattgataa ctcatctaat
     4081 gacactacaa gtacgtttag aaagccggat taccttaaat aaccctttgg tagatgaaat
     4141 taaacagaat tatagtgata tattctttat gactagagaa attcttgcaa atatggacaa
     4201 gttcttggag tggacaatat cagatgatga agtagcatat gtaagtcttc actttttagc
     4261 tgctatggaa cgtagcaaag agagtactaa gtttaatatt cttgctattt gtgcaacagg
     4321 atttggtgca gcccaaatgt taagaaatcg tttggaaacg gagtttggga agcgagtaga
     4381 agttgttgat gtaataggct attatgaatt gaatcaagaa aaacttaaag gaatagattt
     4441 tatagtgtca gctgttgatt tatcaaatct atattttcaa atcccagttt ttaaagttag
     4501 tgtgtttctt aagagtgatg agatggaaat gattagaaaa gctatggatc agatgcaagt
     4561 ttctagttat gtacaatcat caaagattaa caaatttgaa aacaacggct ttagacagta
     4621 ttttagtaaa gaaaactttt taatatgtac tgaatcagac aaggtaaatt tacttgaaaa
     4681 gatggttgag agtttatctg ttggtgaatc aaatgagttt gaacaatctt tactttatgg
     4741 aattaaacag cgcgaagaat taagttcagt tgttttttct gaaaaaattg cagttccgca
     4801 tcctattcag ccctttggta cagagggaaa ggtttcggtt gcaatttgta aagattcgtt
     4861 actctgggat aatcaaagtt cacatgtcca gctagtattt cttctatctc catcaatata
     4921 tgggaacgaa ggtttggcaa ctgtgactaa aaagatagtc tctctgacag agaatgatga
     4981 attgcaaaat cagctaatat cttgcaataa ctttgaagat tttattaaca tatttgagaa
     5041 gataaaatag gaggttcata tgaatcaaga ggaactgcag gttgcagcat ttgaaattat
     5101 cctgcattcg ggaaatgcaa ggtcagaaat acatgaagca tttgcaaaaa tgagagaagg
     5161 tagttttgat gatgcagaaa gtaaattaaa tcaatcaaat gagataattc ttgaagcgca
     5221 tcatgcacaa accaaactct tgcaagaata cgcaagtgga gtggaaatta aaattgaaat
     5281 tatcatggta catgctcaag atcatttaat gaccactatg acattattag aagtagcaaa
     5341 ggaaatgtta gctctttata agaaagttaa ctaaatatgt gttgttatat aaggaggaaa
     5401 tgatatggat aaaaaagaac gacaaaagat tgaacaacaa cgtcgagaga tggctctaac
     5461 taatactttt tttaatcgat atcttcttct acgttattca atagcactct tcttttttgg
     5521 gaatatttat tggcttttga atcagtttat taatccctcg cctattatta ttttccccat
     5581 tatgctcata gtattttcta ttttagcaac tgttgaacaa tttaaactct atggaaatag
     5641 gaaagaaaag ttgggaataa cactaatgtt tgttagaata caaatgctta tttcaatagg
     5701 attacttgtt ttaacttgga caagttggtt taagaatctt tttccgattt ttgaaaataa
     5761 ccaagtagca cgtttatttg tttttgtagt tcttctatta ggtttagttc tgagtttgtt
     5821 agacattaga agaattaaaa aaatttataa acgaacagat aaggcttatc aacaatttgt
     5881 ccaattggaa aagaactcac ttagtttata atcctgatct agtataattt gtatttgaaa
     5941 ctagtcttta gaaagtaaaa attattatgt tttattaagg aggtctattt atggatcaac
     6001 aaaacgggtt gtttggtttt cttgaaaacc atgttatggg accaatgggc aaacttgctc
     6061 agtttaaagt agtgcgtgct atcacggctg caggtatggc tgctgtacca tttactattg
     6121 taggatcaat gtttttggta ttcagtattt tgccacaagc tttctcattt tggccaattg
     6181 tggcagatat tttctctgct tcatttgata aattcacatc actttacatg gttgcaaact
     6241 atgcgactat gggttctcta tctctttatt tcgttctatc acttgcatat gaattgacaa
     6301 aaatttatgc agaggaagaa gaactcaata tgaatcctct taatggtgcc ttgcttgcct
     6361 tgatggcttt tgtcatgaca gtaccgcaaa tcatttttga tggtggaatg atgaagactg
     6421 tgacaagtct aaaagaaggt gcagtaattg cagatggatg ggcaatggga aatggagtcg
     6481 cacgttttgg gacaacaggg atttttaccg caatcattat ggcaattgtg actgttatta
     6541 tttatcgtat gtgtgttaaa cataattggg ttattaaaat gcctgaagct gttccagaag
     6601 gagtttctcg tggatttacc gctttggttc cgggatttgt tgttgcattt gttgttatct
     6661 ttatcaacgg tcttcttgta gcaatgggaa cagatgtttt taaagtcatt gcaattccat
     6721 ttggttttgt atccaatctg actaattcgt ggattggttt aatgattatt tatttactga
     6781 ctcaactact ttggattgta ggtatccacg gtgcgaacat tgtttttgca tttgttagtc
     6841 caattgctct tgctaacatg gctgaaaatg ctgctggcgg gcacttcgct gttgcaggtg
     6901 aattttctaa tatgtttgta attgcaggtg gttctggtgc aactttagga ctatgtttat
     6961 atattgcttt tgcctctaaa tctgaacagc ttaaagcaat aggacgagca tctgtagttc
     7021 cagccttatt taatattaat gaaccattaa tttttggatt acctattatc tataatccag
     7081 ccttggctat accatttatt ttagcaccaa tggttactgc tactatttat tacgtagcga
     7141 attctctaaa ctttattaag ccaattatcg cacaggttcc atggccaact ccagtaggga
     7201 ttggagcttt cttagggaca gcagatcttc gagctgtatt agttgctcta gtatgtgcat
     7261 ttgcagcatt cctagtctat cttccattca tccgtgtata tgatcaaaaa ttggtgaaag
     7321 aagagcaagg tatctaataa gtaaaaaagt atactcgatg atagaatcca tatagtttaa
     7381 ataatgagcg ttaacattag cagtgaagag gtctttttaa gatattcttc tctgcttttt
     7441 catatttttt cgctatgtag ggtatgaagc aaaatagaaa gtagttcgaa tagttgataa
     7501 acagggaact gctgttattt taaaaaaaca ataaagtaaa gtatgttatc gtagaatacg
     7561 atacaatagt aaaaaagcaa aaagaatgcg ttttatattt gggtttgagg cttataaaat
     7621 aggataagca tgctgaaaac ttagatatga caaacaaaat aaaattttta aaagctacat
     7681 agaaacatgg tataatgtat ctaaaggagg tagcatatgt ccttagatat agataaagaa
     7741 aagatgacaa tcatgggaat agcttttgaa aaccgatccg tttttaagag tgtttggtat
     7801 gctttaagta caaatatgat tgaaggatgg cgacctacgg ttagtgatgt tgaaaaatta
     7861 cgagatgaag ctcttgctct ggggatgact taatgaagcg caactgttat gaatcttatg
     7921 actatgttga tccggataat ttatataccg atccgggttc ttcagttcta agaaataagc
     7981 aggaaggaaa aaagcacgtg agcttgaata ttgtatgatt gctagtaaga gtttgaaatt
     8041 atttatcaat cctatcttag ttaatagttt aaaagtagtt tgtttcacaa ctgcataagc
     8101 ttagaaaagt tgaaaagtga taactcttta ataaactctt ggtttgttaa aagatatttt
     8161 gtccactaca ttttttcaat tgactattat ttgtcataga tataacagat agaacattgc
     8221 attcagaata atgaaaaacg catcaaaaat ggtgcgttct gtttttatgc taccataaaa
     8281 ggagggaaac aaattgaaaa tttttaaggg agagttttat cgcatctctg tattaacaga
     8341 caagctagta aggttagaat actctaaaac tggcagtttt gaggatagaa ctacacaact
     8401 tatctataat agagattttg gccaagtttc gttagattat atcgagacat caaacgtact
     8461 agatattatg acggactatt ttcatctgca ctttaataaa ggagaattta acgccgaaaa
     8521 tttatttata gaattaaaag gaaattttgc cgtatatggt agtcgctggt attttggtga
     8581 atcgattgaa acgttaaaag gaacagctcg gactctggat aaggcagatg gagcaatccc
     8641 attagaagat ggaattatta gtcgaaatgg tatagcctta ttggatgatt ctcaaggatt
     8701 tatttgggat gaacagtctg gttatattga gagagaaaat caaattgacc tctatttctt
     8761 tgcctatggg catgattata gaggagcaat cagagacttt taccatttga ctggttcaac
     8821 acccttgtta ccaagatatg ctttagggaa ttggtggagt agatattggc cttatacgtc
     8881 ggatgaatac ttggatttaa tagacagatt tgaaacagag aaaattccat tatctatcgg
     8941 tgtgttagat atggattggc atataactga cattccagct cgttttggaa gtggctggac
     9001 aggatatagt tggaataaaa acttaatacc taatccagaa cagttattgc aacaacttca
     9061 tgatagaaag ttaaaactct ctttaaatgt ccatcctgct gatggtatac gggcttatga
     9121 agaagcttat cctcaagtcg ccaaacgatt agggttaaat gtagaactag aagaacctgc
     9181 catttttgat ttttttaatc cctcttttag ggaagcctac tttaaagatg ttcattatga
     9241 gctagaaaag cagggagtag atttttggtg gattgactgg caacaaggga ctcaaggcat
     9301 attggatcca ctatggcttt taaaccatta tcattatcag gatagttgta aaaatgcaga
     9361 aggtggtttg attttatcaa gatatgcagg tcctggtagc caccgctacc ctgttggttt
     9421 ttcaggggac actattatta gttggaattc cttaagattt caaccttatt ttacagcgac
     9481 agcatctaat atcggttata gttggtggag ccatgatatc ggtgggcaca tgctgggaga
     9541 ttatgacgaa gagctgcaaa ctagatggct acagtttggt gtttttagtc cgatcactcg
     9601 attacatagt tctagaagtc cttttaatag taaagaacct tggttttttt cagaaacaac
     9661 atctaagatt atgaagaaat accttcgttt gaggcatcag atgattccat atctatacac
     9721 tatgaatgta aagacacacg aggaaggtgc cccattaatc agcccaatgt attatttcta
     9781 cccagagaat gatgagagct ataatgttcc aaaccaatac ttttttggaa cagaactaat
     9841 ggtggctccc attgtagaaa agatggactt ggcattccaa tctgcaaaag tggatgtatg
     9901 gttccctgaa ggtgaatggt atgacttctt ttcagagaaa aaatatacag gtggtgtgaa
     9961 gttgagtgtt tatagagaca tttcgactat acctgtgttt gcaaaaagtg gtgcgatcat
    10021 tcccttggtt ggttctgaga tagatatggg tgttgattta cctgaagttg tagattggta
    10081 tgtattccca ggcaaacaac attcttttga aatgcttgaa gatcaaaatg gtcaaagata
    10141 taaaacaaga ttatcaatcg attgggaaat ggggatggta gagttaacat tacaaggaga
    10201 ttctagtatc gttccaagca atagaaggca tagaattcat tttaaaggaa cgaatgtgtc
    10261 tataattgaa ttaccaaata agaatgatac agctagattt gaatgtaaag ataataaaac
    10321 aatatcttta aatgatgaag tttttagact actaaagaca gcttctcttc catatgaatt
    10381 aaaagataga ttgttaaatc aattcatcaa tgcgaaaaac tctcatgact taatgaatat
    10441 cttgcatcat caggataagg aattgagagg gcgtttgttg gaaatgatat ttactagcca
    10501 aaactaattg atataattag aaagtcattt gtttagtgta tatgaagatt ctgtatggta
    10561 ttcgttatca ctggtcacat tgaaaatgtg aaataagcac ctacaacata gactttacaa
    10621 cacttcatgt ttcatatcat ggggtgtttt tctatttaag tcaaagccaa tcaaaaaatc
    10681 tcactattca tcaggttaaa ggaaacctaa tcatagtgag attgtgaatt atagtagagt
    10741 ttgtatcgcc tcttcaattt gttttgggtc tgtttttgaa gaaaagcgtt caaagacttg
    10801 cccatctcga ccgatgagaa acttagcgaa attccattcg actcgttttc ctagtgggcc
    10861 ggatttctgg tcttttaacc agacatagag agggtctgct tccttaccgt tgaccttaat
    10921 cttggcaaaa cgtgggaagg tggtttgaaa atgtaggcta cagaaggcgt tgatttcctc
    10981 tgcgctgccg ggtgcttgtc ccataaactg attgcaaggg aaatccaata tttcaaagcc
    11041 ctgatcttga tagcgttcat agagttcttg aagtccctgg tactggggcg ttaaaccaca
    11101 tccagtagca gtgttgacaa tcaagagaac tttgccacga tagctatcca agggagttgc
    11161 ttggttgttt tggttcaaaa cggaaaaatc ataaagtgaa gtcatgaggg cctcttttct
    11221 ttttctacat tgtaacagtt tttacttttt tcgtcgagtc ggatggaaga tattgttgaa
    11281 gaataagccc tcaatatgat agaaaccgtt tacaaataac tttaaaaatg gtataattta
    11341 attaaaccgg tttacttagt tgctataaat ctctaatttg agatttagtt cctattgatt
    11401 ttacaatatg tttattggag tgtatacatg caaacaaaaa caaagaagct cattgtgagt
    11461 ttgtcttcac ttgttttatc aggattttta ttaaaccatt atatgacagt tggagcggaa
    11521 gaaacgacta cgaataccat tcagcaaagc cagaaggaag ttcagtatca gcaaagggat
    11581 acaaaaaatt tagttgaaaa tggtgatttt ggtcagacgg aggacggaag cagtccgtgg
    11641 acaggaagca aagctcaggg gtggtcagct tgggtagacc agaagaatag ttctgcagat
    11701 gcctcaactc gagtcattga ggctaaggat ggggctatca ctatctcaag ccctgagaaa
    11761 ttaagggcag cggttcaccg tatggttcct attgaagcta agaaaaagta taaactgcgt
    11821 ttcaagatta aaacagatca taaagtcggg attgccaaag ttcgtatcat tgaggaaagt
    11881 ggtaaggaca agcgattgtg gaattctgca acgacgtcag gaacaaagga ctggcagacc
    11941 attgaagcag actatagccc gactttagat gttgataaaa tcaagctgga gttattctat
    12001 gaaacaggaa ctgggactgt ttcctttaag gatattgagc tggtagaggt agcagcccag
    12061 ctttctgagg attctcaaac agataaacag cttgaggaaa agattgattt accaattgga
    12121 aaaaaacatg ttttttctct tgcggactat acttataagg tagaaaatcc tgacgttgct
    12181 tcagtcaaaa atggaatttt agaacctctt aaggaaggga caaccaatgt cattgtcagt
    12241 aaagatggca aggaagtgaa aaagattcct ttgaagattc tagcctctgt taaggatgca
    12301 tacacagacc gtttggatga ctggaatggc atcattgctg ggaatcaata ctatgattct
    12361 aaaaatgaac agatggccaa attaaaccag gaattggaag gaaaggtagc tgatagccta
    12421 tctagtattt caagtcaggc ggaccgcacc tatttgtggg aaaaattttc aaattataaa
    12481 atgtctgcaa atctgactgc cacttatcgg aaattggagg agatggccaa gcaagtgacc
    12541 aatccttctt ctcgttatta tcaagatgaa actgtcgttc gaacagtcag ggattccatg
    12601 gaatggatgc ataaacatgt ctacaatagt gaaaagagca ttgttgggaa ctggtgggat
    12661 tatgaaatcg gtacacctcg tgccatcaac aataccttgt ctctgatgaa agaatacttc
    12721 tctgatgagg aaattaaaaa atatacagat gtgattgaaa aatttgtacc agatcccgaa
    12781 catttccgaa agacgactga taacccattt aaggctctag gtggaaactt agttgatatg
    12841 ggaagagtaa aagtaatagc tggtttactg cgtaaggatg atcaagaaat ttcttctacc
    12901 attcgctcga ttgagcaagt gttcaagttg gtagaccaag gtgaaggttt ttatcaagat
    12961 ggatcctata tcgaccatac caatgttgcc tatacgggtg cttatgggaa tgttttgatt
    13021 gatggcctgt ctcaactgtt gccagtcatt caaaagacca agaatccaat cgataaagat
    13081 aaaatgcaaa ccatgtacca ctggattgat aaatcgtttg ctcctttgct ggtgaatgga
    13141 gagctgatgg atatgagtcg tggacgctcg atcagtcgtg caaatagcga ggggcacgtg
    13201 gccgcagtag aagtactaag agggattcac cgaatagcgg atatgtctga aggagaaacc
    13261 aaacaacgtt tgcagagtct tgtgaagacc attgttcaat cggatagtta ttatgatgtc
    13321 tttaagaatt tgaagactta taaggatatc agtttgatgc aatccttgtt aagtgatgca
    13381 ggagtcgcaa gtgttccaag aacaagttac ctatctgcct ttaacaagat ggataaaaca
    13441 gccatgtaca atgcagagaa agggtttgga tttggcttgt cactcttttc cagtcgtacc
    13501 ttgaattacg aacacatgaa caaggaaaat aaacatggtt ggtatacgag tgatgggatg
    13561 ttctatcttt acaatggcga tttgagtcac tatagcgatg gctactggcc aacagttaat
    13621 ccatataaga tgcctggtac aacagagacg gatgctaaga gagcggatag cgatacaggt
    13681 aaagttctac cgtctgcttt cgttggaacg agcaaactag atgatgccaa tgcgacagca
    13741 accatggatt tcaccaactg gaatcaagta atccatataa agtctatgtc aatgataaag
    13801 aagcctccct tacagaacaa gaaaaggatt atcctgaaac ccaaagtgtc tttttagaat
    13861 cgtccgattc gaaaaagaat attggttact ttttctttaa gaagagttca atcagtatga
    13921 gtaaggcttt gcaaaaggga gcctggaagg atatcaatga aggacagtca gacaaggaag
    13981 ttgaaaatga atttcttacg attagtcagg ctcataagca aaatggagat tcttatggct
    14041 atatgctaat tcctaacgtg gatcgtgcca ccttcaatca aatgataaaa gagttagaaa
    14101 gtagcctcat cgaaaatagc gaaacccttc agtctgttta tgatgctaaa caaggagttt
    14161 ggggcattgt gaaatatgat gattctgtct ctactatttc caaccaattc caagttttga
    14221 aacgtggagt ctataccatt cgaaaagaag gggatgaata taagattgcc tactataatc
    14281 ctgaaaccca ggaatcagct ccagatcagg aagtctttaa aaagctagag caagcagctc
    14341 agccacaagt acagaattca aaagaaaagg aaaaatctga agaggaaaag aaccattcgg
    14401 atcaaaagaa tctccctcag acaggagaag gtcagtcaat cttggcaagt ctagggttct
    14461 tgctacttgg ggcattttat ctattccgta gaggaaagaa caactaattt gttcatcatc
    14521 tagatgaatt acatgaaact gtggaaaata gaaaaaatcc gaagaaggcc aaatatcttc
    14581 ggatttttct tttaaaaaag gataagttga tacttatcct tttttacttc attattatgt
    14641 gactatagcg ttttgaaact agaatagaac gttataactg ctaaaagatt tctataaatt
    14701 catttgattt tcctaatcaa tttgttcgta tcctatttca ctccactata taagtccgtc
    14761 tcgctccgtg aggtgcgcgt cgaaggttat accaaaaaaa ctccaaacgc gatacaataa
    14821 aggtattcaa tccaattgta aagcgaaagg agaaaaaata tggcacaaaa gactcatagt
    14881 ttatcataca caaagtggat gtgttctatc atattgtgtt cacccctaag tatagacgaa
    14941 aagtcatcta taatcaatat agaagtagtt taggcgaaat atttcatcgc ttgtgtagtt
    15001 ataaaggtgt tgaaatgatc gagggtcact taatgccaga ccatgtacac atgttagtca
    15061 gtattccgtc gaggctaagt gtttcaagtt ttatggggta tttaaaaggc aaaagtgcac
    15121 tcatgatgtt tgacaaacac gccaatctca agtacaagtt tgggaatcgg aatttctggg
    15181 cggaaggtta ttatgtaagt ccagtagggc ttaatgaagc cacaattaag aaatatagtc
    15241 aagattaaag aaattatcga gtggatgatt tcttcacgag tatgaaaatt tgagaactag
    15301 taaagtatga tatatagtaa aatgaaataa gaacaggaca aaatcgatca ggacagtcaa
    15361 atcgattttt aacaatgttt tagaagtaga ggtatactat tccagtttca atctactata
    15421 gcactagata aattgagtgt aaaagaatat gaggatccct ttagggatag tggtaagtaa
    15481 taccaaagtc tcttaaagag gcaagtgacg agtcaagagc aataaggctt gaacaacgtg
    15541 aaagccagcg tctttaggcg ctggctgatg atttgggctt atagctctga gataaaccac
    15601 ccgttagacg ggtagttatg attttatctg agtgtaatat actgttgggc aatctcgctg
    15661 atgcggtcaa agttgccttg ggaagcgagt ttattgagtt cgccaccaat tccaacggca
    15721 tctgcaccag cagcgaacca ttgagggatg ttgtttaggc cgactcctcc ggttaccatt
    15781 acggaaactt gtgggatcgg tgccttgact gcagagatat atgctggact gagagtacta
    15841 cctgggaaga gtttgatgat ttcactaccg gcttcaagtg cagtcgtgat ctctgtgagg
    15901 gtaatacagc ctggaatgta cggtgtgctg tagagattgc acattttcgc agtttcagca
    15961 tggaaagatg gagaaacaac gtaatttgct ccagctagaa tggcatctct agcagttacg
    16021 gcatcaagca cagtacctgc accgatacaa acactctgat cgtcctgata caagtctaca
    16081 agttccttga tgatttgtcc tgcatactga ttggtatagg cgatttcaat agctttgata
    16141 ccgcccttga tacaagcaat cgaggcttgt agtccttctt cctttgtatt tcctcgaatg
    16201 acagcgacaa ttttctgttt ttttagttca ataatcgtat ctgatttggt catgtaattc
    16261 tcctaacgaa tgatatcttg tgcatttgcc agtaaatttt caatactagt tgcggaagtg
    16321 gagagatggt ctcctggaag agtgcatttg agagttgcgc tcgcaactgc aaagtcaatg
    16381 gtagttttta gggaggaatg atggagtagt tggtaaaggg caccagatat aaaggcatcc
    16441 ccgctaccaa ttcgttgata gactgcagtt tttagttgga cagactcttc aaatcgttct
    16501 tccagagcat aggcttgata gacatttttg tcttgctcat cactagatcg gagggtatgg
    16561 aaaatggcct tgaaaccata ggcttctttt aaaagtcgca tgcgattttc cacctcttct
    16621 aggctagcac tgtctcttgg aaacatctct agattttggt catcaatcat gagaggatca
    16681 ataccgaagc aatagtcagt aaaacgtgca aacttagaaa attcatactt ggcttctagg
    16741 actgaaatca tctttgttct cagattgaga tccattgaaa cgacaattcc tcggcgcttg
    16801 gcttcttcca agagtaggag aaggatcgca cggacctctt gaccgatagc tatggtgatt
    16861 ccactaaaat gaaaatggct aatcccctga aagagagaat ccatatctag catgtttggc
    16921 cgaatctggc tgatactcgt atgcttacga tcgtagaaaa cttcactttg acgacaacca
    16981 aagccgttct ccaaatagta gaggccgatt cgatcgccaa gccgacagat tgaactggta
    17041 tcgatttggt gctgtttcaa gaatgtgaga aaacgatctc caatctcgtt ggcagggagt
    17101 gcggtaaaga ctttcgttga gatacccagg gcttgcaaat tacaagcgat gttaatttct
    17161 gatccgccaa aataagtcga actggcaaca tgatcgccga tactggtggc atctaatggt
    17221 gagattcgaa ttaatggttc gccaaacagt aatattttcg tcatccatta gttcctttct
    17281 ggtttagaat agctttactt ggctaatact tctttcaaat aagcagcgac ttcatcatct
    17341 tggcagtttt caaagaagta ttcttggaag tatttgccag agatggtgtc tttgaggaag
    17401 tcttggtcga ttgttttaag gatggtcatc aaatcattgt gggtgatttg tttcacctcg
    17461 tttaagatac gagcgttacg ttgttcaggg attacacgtt ctcttgggta gccaccgccc
    17521 atttcttcag caaataagcg ttcaaacatc aatttgaggg tcagttctgc cccccagcca
    17581 aatcctttgg cataagggat agacaaggcg ttaccaccat tgatttgaga ataaaggtaa
    17641 gcgtcagttg ggtccactgc tagaccacag acaacaccag ggaagctgtt taaagcaagc
    17701 atagccccta cacccgtacc acagccggta acaacaaagt caactgcctt tgtatttaaa
    17761 aggatggcag ccattagtcc gttctgcaca taagttaatt gactttctcc ttcttctcca
    17821 cgcataccat agttaaataa ttggtagtct tttttatctg tcgcttcttt tagactatcg
    17881 taaataatgt gattcttgct agcttgacta ttttcattga ttaatgcgat tttcataaga
    17941 tcttctttct atttttactc aggttgtttt ccgatgtagg ctaagatacc gccatctaca
    18001 tataggatgt ggccattgac aaaattgctg gcatcactag cgagaaagac agcagggccc
    18061 atcaaatctt caggatttcc ccaacgtgca gcaggtgttt ttgcaatgat gaactggtca
    18121 aatgggtggc gagaaccatc ttcttgcaac tcacgaagag gtgctgtttg aggagtggca
    18181 atataacccg gtccaattcc gttacattgg atattggctc caccgtattc agacgcaatg
    18241 ttgcgggtca acattttcaa gcccccttta gcagcagcat aagcgctaac tgtttcacgt
    18301 cccagttcgc tcatcatcga acaaatattg ataatctttc catgcccttt ctttatcata
    18361 gaaggaataa ctgcctttga aacgataaat ggtgcgttta agtcaatatc gatgacctta
    18421 cggaaatcag cggcgctcat ttcgcacatt ggaactcggc ggataatacc agcgttatta
    18481 acgaggatgt caatgacacc aacctcttgt tcgatttgct tgaccatggc ttggataccg
    18541 tcctcgtctg tcacgtcaca gacatatcca tgggcttcga tgccaacttc acgataagct
    18601 tcaatccctt tattgaccag atcttgattg atatcgttaa agacaatagt agcgccggct
    18661 tcagcgtagg atttggcaat agcaaatcca attccataag aagcgccggt gatgagagca
    18721 atttttcctt ttaaagaaaa ctgctcaatt gagaatgatg tatttgtcat ttgatacttc
    18781 ctttcaaatt tgttaagact tctctataa
//
LOCUS       DAVKEV010000041        18339 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVKEV010000041 DAVKEV010000000
VERSION     DAVKEV010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18339
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.041"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(85..1020)
                     /locus_tag="VWZ68_001632"
     CDS             complement(85..1020)
                     /locus_tag="VWZ68_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEU9372633.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1017..1877)
                     /locus_tag="VWZ68_001633"
     CDS             complement(1017..1877)
                     /locus_tag="VWZ68_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU9372634.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            1985..4147
                     /locus_tag="VWZ68_001634"
     CDS             1985..4147
                     /locus_tag="VWZ68_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU9372635.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYFYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4239..5498
                     /locus_tag="VWZ68_001635"
     CDS             4239..5498
                     /locus_tag="VWZ68_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9372636.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5512..6378
                     /locus_tag="VWZ68_001636"
     CDS             5512..6378
                     /locus_tag="VWZ68_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9372637.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTRWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6392..7225
                     /locus_tag="VWZ68_001637"
     CDS             6392..7225
                     /locus_tag="VWZ68_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9372638.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKLTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7226..7306
                     /locus_tag="VWZ68_001638"
                     /pseudo
     CDS             7226..7306
                     /locus_tag="VWZ68_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7583..9025
                     /gene="gtfA"
                     /locus_tag="VWZ68_001639"
     CDS             7583..9025
                     /gene="gtfA"
                     /locus_tag="VWZ68_001639"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEU9372639.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRSVVKALLNLFSFRNRSEAFDLEGTIEIETPTVHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9163..10356
                     /locus_tag="VWZ68_001640"
     CDS             9163..10356
                     /locus_tag="VWZ68_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU9372640.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11043..13022
                     /locus_tag="VWZ68_001641"
     CDS             11043..13022
                     /locus_tag="VWZ68_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9372641.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13089..14585
                     /locus_tag="VWZ68_001642"
     CDS             13089..14585
                     /locus_tag="VWZ68_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9372642.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14585..15511
                     /locus_tag="VWZ68_001643"
     CDS             14585..15511
                     /locus_tag="VWZ68_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9372643.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15520..16587
                     /locus_tag="VWZ68_001644"
     CDS             15520..16587
                     /locus_tag="VWZ68_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9372644.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16598..17524
                     /locus_tag="VWZ68_001645"
     CDS             16598..17524
                     /locus_tag="VWZ68_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9372645.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
     gene            complement(17599..18339)
                     /locus_tag="VWZ68_001646"
                     /pseudo
     CDS             complement(17599..18339)
                     /locus_tag="VWZ68_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5399 a         3252 c         3863 g         5825 t
ORIGIN      
        1 caataaaact tcagatccgt aaaacttaat tgaattacta atctgaagtt atttttatat
       61 cgtttatatt ataattgtgt tattttactt ccaactattg agagaaattt cgccactatt
      121 tagccagatt tcttttccgt tatcacattg aactaaaagt tttccatttt ctgagatgtc
      181 tttagcaagt cccttgtagt ctttttgctc tagtgtgaaa gtgacttctt ttcctagaat
      241 gaatgactgt tttttgtata ggtataatag ctcttctgct ggtgtttcga agaaagcacg
      301 ccagatttct atgatcaatt cattccttgt tataggagct gtagctttaa ataagctggc
      361 agctttttct tttaattcct gagggaagtc tttaatagtg aaattgatac ctactccaat
      421 aatgatatct gtgactaagc cagtttctac agaggtcatt gcttcagtaa ggattcctcc
      481 aattttatga ttgtttagat agatatcatt gacccatttt atgtcgacat ctattaaagt
      541 taggttctta atggctttgt agacagctcc agctacaagt agtgtgtagg atggtaattt
      601 gtcatagggg agatttggtt taagatggag tgtcatataa ataccacctt gtggtgagta
      661 gaaggaacgt tgaaaacggc ctcggcctgc tgtttgatag gaagctagat agagggtatt
      721 tgcttcatgg cctaaatcaa ttgcttcttt tgcatctagt tgtgttgatt ttgtttcggg
      781 tttaaagctg actttaattg gaagattttc ttctagaatc tctggaagaa taaggtcacc
      841 attcatcagt ttatatcctc tatttttgat actatcaatt tcaatgcctt cttgttctag
      901 tcgcttgatg gctttccaaa ttgctgttcg gcttagggat agtttttctg cgattttttc
      961 tccgctgata tagtcggttt ctttagatag gatttggtag acagcttggt aggatttcat
     1021 aatgttgcct ttcttactag ttggtattga gagtattctt ttcttgtatg acttggagtc
     1081 tgattaaagt attgtttata agctttcgaa aaatggagtg gatctgaaaa acctaccgag
     1141 tatgcaatta ccttgatgga ctcttgggta ttttcgagaa gttgtctagc tcggtgcatt
     1201 cgaacgtaga gtaggtattc tttgggtgat aaggtattaa attctttgaa tacgcttgat
     1261 aagtagcttc tgtgaacgga tagttctttt gctaaatctt gaattgtaag tgattgagga
     1321 tagtggctat caattaatcg tttgcattca agatagagtt ggtgggttga tgaaatattc
     1381 ttttttttct gattgggagc aatagttccc agatgaaaca tcagttcatg aagttgtccc
     1441 atgatatgga gttgagctaa ttcacttgat tttgtaatct gagcgaagcg gacaatgtct
     1501 gagatgagtt ttgcagtagt ctgggtatga caagtttcag attggatgag ataggattga
     1561 tcagaaattt gggaaagagc aaaataatca ggggctttcc ctccagtgat tcctaaccag
     1621 tagtaggccc aaggttcttt actatctgct tgataaaagg ttagttcctc tggttttaat
     1681 agaaagaaat ctccttcttt taaatcaaca attttaccct tgtaatgaaa ttttccttgt
     1741 cctttagtaa tgtaatgtag gacgtatgta tcacgaatgg ctggaccaaa agagtaatta
     1801 ggtgtgcatt cctcatatcc ataaaagctt agggcaaggt cgattgttcc agtctggtat
     1861 tctgaaaaaa ctaacatgtg ctacctccta cctaacattt taccatattc ttgagacatt
     1921 tttctatttt ggaaagcgat ttcaggtgat aaaatagagt caataaagtg atgaggtgaa
     1981 gtaaatggga gttaggatag agaataatct attttatgtt gagagtaaaa atctaagttt
     2041 gattattgaa aatcgaaatg gctacttact tttgaaacat ttaggaaaga ctattaagaa
     2101 ctataaaggt tccaatagtg tttatgaacg agaccatgcc ttttcaggaa atccaacagc
     2161 tactaatcga acctttagtt tagatactca acgtcaaatt tttggacaac atggcttagg
     2221 agattttagg aaaccaacca tacaggttca gcataatgta actgaagtaa cagactttcg
     2281 atttgtagaa gcaaagattt taaaaggtca gaatggtcca cagggcttac cttctccaca
     2341 tagcatggac gatacagaga ctcttgtctt aatgttagaa gattctaagg ctcaacttag
     2401 tctgactttg tattatacta cttttaataa tgatgcgact attgctagct acagtaaatt
     2461 agataataat agtaatcagg aagttgtcat ccataaagat ttttctttta tggctgattt
     2521 tccagctgca gattacgaaa tagtaactct gcagggtgct tatgctcgtg aaaagactgt
     2581 tagacgtcaa caggtagaac aaggaatctt ttcgattagt tcaaaccgag gtgcttctgg
     2641 tcatgctcaa acaccagctc ttctactatg cgaacaagga gtcacagagg atgctgggaa
     2701 tgtgtttgct attcaactaa tgtatagtgg caactttgaa gcttttgttc aaaaaaatca
     2761 attgaatgaa gttcgggtgg ctattggcat taatccagaa aacttttctt ggaagttagc
     2821 ccctgaggaa tactttgaaa caccggtagc tttagtgact cattcagatc agggattaac
     2881 tggtattagt catgaaagtc agaattttgt actgaagcac attatgctaa gtgaattttc
     2941 taaaaaagaa cgtccaattc taatcaataa ctgggaagct acttactttg actttcagag
     3001 agaaaaactg ttagagttag cagatgaagc taagaaagtt ggcattgaac tttttgtatt
     3061 agatgatggt tggtttggca atcgttttga tgataatcgt gctttaggtg attgggttgt
     3121 taatgaggaa aaactgggtg gaagtctaga aagtctgatt tcagctatcc atgaaagagg
     3181 tttgcagttt ggactttggt tagaacccga aatgatttct gtagatagtg atttgtatcg
     3241 tcaacatcct gactgggcta ttcaggttcc tggctatgag catacttatt ctcggaatca
     3301 attagtactt aatcttgcca atcctcaggt agtagaatac ttgaaaagtg tcttagatca
     3361 actcctatct tatcatgaga ttgattacat taaatgggat atgaaccgca atatcactaa
     3421 gctagggaat ggattaactt atctagagac acagatgcaa tctcatcagt acatgctggg
     3481 gctttatgaa ctcgtttctt atctgacaga gaagcacagc catattctct ttgagtcctg
     3541 ctctggtggt ggtggacgaa atgatcttgg tatgatacgc tatttcccac aagtctgggc
     3601 tagtgataat actgatgcca ttgcacgttt accaattcaa tacggttcat cctatttcta
     3661 tccaaccatt tctatggggg ctcatgtgtc agcagtaccg aatcatcaga tgggacgaat
     3721 gacaccatta gaaacacgtg gccatgtagc aatgatggga aatttgggct atgagcttga
     3781 tttgacaaat ttatcagatg aagagaaagc tacgattgct aatcaggtga acttgtataa
     3841 agaattacga ccagtagttc agttaggaca gcagtataga ctaattaatc ctgatactgc
     3901 atccaatgaa gcagctgtac aatttaatta cggaaatcaa acgattgtaa cctacgttcg
     3961 cgttttatct gttgtagaga ccatggaaac aactttaaaa ttaaaagatt tggatgaaga
     4021 gggactatat aaattacagg aaaatggcga agtttactca ggtgcagaac taatgtatgc
     4081 gggcttaact gttatcttat cccaaggaga ttttttgagt agacagtata tttttagaaa
     4141 actatgatat gtactgaccc caaaagttag atttattctg tctaactttt ggggtgcagt
     4201 tcaataaggg tgtataaatt tataaaggag gctttctaat ggaatggtat aaaaaaatcg
     4261 gacttcttgc aactacaggt ttagctttgt ttgggctcgg cgcttgctcc aactatggta
     4321 aatctgcgga tggcacagtg accatcgagt atttcaacca gaaaaaagaa atgaccaaaa
     4381 ccttggaaga aatcactcgt gattttgaga aggaaaaccc taagatcaag gtcaaagtcg
     4441 tcaatgtacc aaatgctggt gaagtattga agacacgcgt tctcgcagga gatgtgcctg
     4501 atgtggtcaa tatttaccca cagtccattg aactgcaaga atgggcaaaa gcaggtgttt
     4561 ttgaagattt gagcaacaaa gactacctga aacgcgtgaa aaatggctac gctgaaaaat
     4621 atgctgtaaa cgaaaaagtt tacaacgttc cttttacagc taatgcttat ggaatttact
     4681 acaacaaaga taaattcgaa gaactgggct tgaaggttcc tgaaacctgg gatgaatttg
     4741 aacagttagt caaagatatc gttgctaaag gacaaacacc atttggaatt gcaggtgcag
     4801 atgcttggac actcaatggt tacaatcaat tagcctttgc gacagcaaca ggtggaggaa
     4861 aagaagcaaa tcaatacctt cgttattctc aaccaaatgc cattaaattg tcggatccga
     4921 ttatgaaaga tgatatcaag gtcatggaca tccttcgcat caatggctct aagcaaaaga
     4981 actgggaagg tgctggctat accgatgtta tcggagcctt cgcacgtggg gatgtcctca
     5041 tgacaccaaa tgggtcttgg gcgatcacag cgattaatga acaaaaaccg aactttaaga
     5101 ttgggacctt catgattcca ggaaaagaaa aaggacaaag cttaaccgtt ggtgcgggag
     5161 acttggcatg gtctatctca gccaccacca aacatccaaa agaagccaat gcctttgtgg
     5221 aatatatgac ccgtccagaa gtcatgcaaa aatactacga tgtggacgga tctccaacag
     5281 cgatcgaagg ggtcaaacaa gcaggagaag attcaccgct tgctggtatg accgaatatg
     5341 cctttacgga tcgtcacttg gtctggttgc aacaatactg gaccagtgaa gcagacttcc
     5401 ataccttgac catgaactat gtcttgaccg gtgataaaca aggcatggtc aatgatttga
     5461 atgccttctt taacccgatg aaagcggatg tggattagga gtagagagac tatgaaaaaa
     5521 gtattacaaa aatattgggc atgggctttt gtggtcatcc ccctcttgtt acaagcaatt
     5581 ttcttctatg tgccgatgtt tcaaggagcc ttttacagtt ttaccaactg gacaggattg
     5641 acttacaact acaaatttgt cggcttaaac aactttaagc tcctcttcat ggatccaaaa
     5701 ttcatgaatg cgattggctt taccgcaatc attacgattg ccatggtggt tggtgagatt
     5761 gcactcggga tcttcattgc gcgtgtcttg aactctaaaa tcaaaggcca aaccttcttc
     5821 cgtgcttggt tcttcttccc agctgtttta tctggtttga cagtggcttt gatcttcaag
     5881 caagtcttca actacggtct tccagcgatt gggaatgccc ttcatattga atttctccaa
     5941 accagtcttt tagggactag gtggggagca atctttgcgg ctgtctttgt ccttctttgg
     6001 caaggggtgg ctatgcccat catcatcttc ctagctggtt tgcaatctat tccaactgag
     6061 attacagagg cagcaaggat tgatggtgcg actagcaagc aagttttctg gaacattgaa
     6121 ttgccttact tgctaccaag tgtctctata gtctttatcc tagccctaaa aggtgggctg
     6181 actgcctttg accaagtctt tgccatgacc ggtggtggtc caaacaatgc cacaacctca
     6241 cttgggctct tggtttataa ctatgccttt aaaaacaacc aattcggtta tgccaatgcc
     6301 attgccgtaa tcttgttctt cttaattgta gtgatttcga tcatccaatt gagagtatct
     6361 aagaaatttg aaatttaaga ggagaagcat gatgaaacaa gatgaaagaa aagccctgat
     6421 tggcaaatac attctattga ttctaggatc ggttctgatt ttagtgccgc tccttgctac
     6481 cctctttagt tccttcaaac tcactaagga tattgtagat aatttctttg gctttccaac
     6541 caacttcaca tgggacaact ttagccgtct cttagctgat gggattggag gctattattg
     6601 gaactctgtc gtcatcactg tcttgtcttt acttgcagta atgatcttta tccctatggc
     6661 agcctactcc atcgctcgca atatgagtaa aagaaaagcc tttaccatca tgtataccct
     6721 cttaatcctc ggaatcttcg tacctttcca agtcatcatg attccgatta cggttatgat
     6781 gagtaaactc ggtttggcta atacctttgg tttgatcttg ctctacttga cctatgcgat
     6841 tccacagacc ctctttctct atgttggcta tatcaaaatc tcgattccag aaagtctgga
     6901 tgaagcagca gagatcgatg gggctaatca atttacaacc tatttccgca tcatcttccc
     6961 aatgatgaaa ccgatgcatg cgacaaccat gatcatcaat gccctttggt tctggaatga
     7021 cttcatgttg ccactccttg tcttgaaccg ggattccaaa atgtggactc tgcctttgtt
     7081 ccaatacaac tacgcaggcc aatatttcaa cgactacgga ccaagctttg cctcttacgt
     7141 ggtcggcatt atcagtatca ccattgtcta tctcttcttc caacgccata tcatttcagg
     7201 aatgagcaac ggggcagtga agtaatactc aatgaaaatc aaagagcaaa ctaggaagct
     7261 agccgcaggt tgctcaaaac actgttttga ggttgtggat gaaactgacg aagtcagtaa
     7321 ccatacctac ggtaaggtga agctgacgtg gtttgaagag attttcgaat agtataagaa
     7381 gagctcatgg aatctatagt ctttgacaca gaggaagagt tcagcttgtt gataattcta
     7441 tgtagaaaac aagaaagtag tactttgttt atcacagtct atattagtac gagtttgatg
     7501 ataaatagag atttaaaatg aattttattt atgaagccag atcatatgag acttggcttc
     7561 aattagaaaa aggagagtaa tgatgccaat tcaaaataaa accatgttga ttacctattc
     7621 tgatagcctt ggaaataatc ttaaagactt atatgataat ttggaagagc attttggaga
     7681 tgctattgga ggagttcacc ttttaccatt tttcccatca acaggtgatc gtggatttgc
     7741 gccagttgac tacgacgaag tggactcagc ttttggtgat tgggaggatg ttaagcgttt
     7801 aggtgagaga tattatctta tgtttgattt tatgattaat catatttctc gtcaatccaa
     7861 gtattataag gactatcaag aaaaacatga agccagtgaa tttaaagatc tctttttaaa
     7921 ctgggataag ttttggccag aaaaccgtcc gacacagtct gatgtagatt taatttacaa
     7981 gcgtaaggat cgtgcaccaa agcaagagat tgtgtttgaa gatggttcag tggaacattt
     8041 gtggaatacc tttggtgagg agcagattga tcttgatgtg accaaagaag taactatgga
     8101 atttatccgt aagaccattc agcacttggc aagtaatggg tgtgatttga ttcgtctaga
     8161 tgcctttgct tatgcagtga agaaattgga tactaatgat ttctttgtgg aaccagatat
     8221 ttgggattta ttggacaaag ttcgagatat cgctgctgag tatgggacag agcttttacc
     8281 tgagattcat gaacactatt cgattcagtt taaaatagca gaccatgatt actatgttta
     8341 tgattttgct cttccaatgg tgacacttta tactctttac agttccagaa cagagcgttt
     8401 ggctaagtgg ttaaagatga gcccgatgaa gcaatttacg acgctagata cccatgatgg
     8461 gattggagta gtagatgtca aggatatcct gaccgatgag gagattgact atgcttcaaa
     8521 tgaactctat aaggttggag ccaatgtcaa acgtaagtac tctagtgccg agtataacaa
     8581 cttagatatc taccaaatca attcaaccta ctattcagcg cttggagatg atgatgtcaa
     8641 gtattttctc gctcgtctaa ttcaagcttt tgccccaggt attcctcagg tttactatgt
     8701 gggtctatta gcaggcaaga atgacttgaa attattagaa gaaactaaag aaggtcgaaa
     8761 tattaatcgt cattactata gcaacgagga aatagcaaaa gaagtgcaac gatctgttgt
     8821 gaaggccctt ctcaatctat tttctttccg taaccgttca gaagcctttg atctagaagg
     8881 gactattgag atagagacac caacagttca cagcattgta atcaaacgtc aaaataaaga
     8941 taagtccgta acagcagtag cagaaattga tttgcaaaat cagacttatc gggtaattga
     9001 gaatggagtt gaagtaacat tttgaagcct tgatatggtg gataaaatag ggtttttatt
     9061 ttggaaaacg tttcctttgt tttcaaattg ctaaaaaagt ggtacaatat aggatagctt
     9121 actattatct gaatcagctg atttggagag aaaggattca ttttgaaatc aataggcttt
     9181 attgaaaagc tgaaggggtt gtctagtaaa gagctgattt tattgggaat tatcctaagt
     9241 atctttttac ccttttatct ttttgtagtt gtactctgtt tatatattat cagtttgatt
     9301 tttacaggag acatgaaaag tattcttcag aaaatggggg agcatccgat gctgcttctt
     9361 tttcttagct atagtactgt tatatccatt cttgcacaaa attggatggg tcttgtggct
     9421 tcagtaggaa tgtttctatt tactattttc tttttgcact atcagtcgat tttatcccat
     9481 aaattctttc gattgatttt gcagttcgtc ttgtttggta gtgtcttgtc agctgctttt
     9541 gccagtttag aacatttcca aattgtgaag aaatttaact atgcttttct ttcacccaat
     9601 atgcaggtgt ggcatcagaa ccgggcagaa gtgactttct ttaatcctaa ttattatgga
     9661 attatttgtt gtttctgtat tatgattgct ttctatctgt ttacaacgac caagttgaat
     9721 tggttgaaag tattctgtgt gattgcaggc tttgttaatc tctttggttt gaactttact
     9781 caaaatcgaa ctgcctttcc tgctattatc gctggagcaa ttatctatct ctttacgact
     9841 attaaaaact ggaaggcctt ttggcttagt attggggtct tcgcgattgg tttgagtttc
     9901 ctcttttcta gtgatttggg agttcgaatg ggtactttag actcttctat ggaagaacgc
     9961 atttctatct gggatgctgg gatggccttg tttaagcaaa atcctttttg gggtgaaggg
    10021 ccattgacct atatgcactc ttatcctcgg atacatgctc cttatcatga acatgcccac
    10081 agtctttata ttgatacgat tctgagttac ggaattgtgg gtaccatttt attagttttg
    10141 tcttctgttg ctcctgttcg cttgatgatg gatatgagtc aggagtcggg gaaacgtccg
    10201 attatcggcc tttatctatc tttccttaca gtggttgctg tgcacggaat ttttgacttg
    10261 gctctcttct ggattcagtc aggctttatt ttcttgctag ttatgtgcag tattccattg
    10321 gagcatcgaa tgttggtatc ggacatgacg gattaagttt tataagtttg aaatcttcta
    10381 ccttgggtag gagatttttt tatacgatgg gcatgtcgtg catctgaggt gtaagtcctc
    10441 tgtagggatc cactaccggt gaatacaata gcgctcccca agcctgacta tcgtgaggta
    10501 gcggattaaa atggtctggg gatagatcgt tttaagtctg acgcaggaaa taagaattgt
    10561 cagagaaagc aatagtgaaa tcgtaggcta tgaatagaaa cgtgatagcg aggagcatat
    10621 agtggataag gtagcgagaa attttaaagt ataaaagata gtcttaatct atatatgtaa
    10681 atcacaaaag taattgaatt cggaataagg ttggtgtgaa aagacatagt aaactgaatc
    10741 ttgaatacta gaatgatact tctacaatat tgttataatt taatttgaat tccaaaatca
    10801 cattgttccg tccgtatttc attttactgt atgtcttcct aaactccaaa gtttctgcgt
    10861 caaatttcct attttcactg tagtctttga cacttcgaac gacaatttga atcatatatt
    10921 caaaaaaaaa tgaaaaattt gtgccaacaa gcctaaatat tctgaaaatt tgtttgattt
    10981 ttaatggata atgtgatata atggttgtca atctataatt cacataaaca gaggagtaga
    11041 aaatgaaaaa aaatcgtgta tttgctacag caggtcttgt tttattagca gcaggtgtac
    11101 ttgcagcatg cagttcttca aaatcatctg attcatcagc ccctaaagct tatggctatg
    11161 tttatacagc agacccagaa accttggact acctgatttc aagtaaaaat agtacaacag
    11221 tagtgacttc aaatgggatt gatggtttat tcactaacga taattacggt aatcttgctc
    11281 ctgcagttgc agaggattgg gaagtctcta aggatggttt gacctacact tataagattc
    11341 gtaaaggggt taaatggttt acctctgatg gagaagaata tgcagaggtg acggctaaag
    11401 atttcgtgaa cggtttaaaa cacgcagcag ataaaaaatc agaagctatg tatttagctg
    11461 aaaattcggt taaaggcttg gcagattatc tatcaggaac ttcaacagat ttttcaacag
    11521 ttggtgtcaa ggcggttgat gattatacgt tacaatacac tttgaaccag cctgaaccgt
    11581 tctggaactc taagttgacc tattctattt tctggcctct gaatgaagaa ttcgaaacat
    11641 caaaaggaag cgattttgct aaaccaacag atccgacatc cttgctttat aatggtccat
    11701 tcttgttgaa agggttgact gcaaaatctt ctgtagagtt tgtaaaaaat gagcaatatt
    11761 gggataaaga aaatgtccac ctagatacta tcaatctagc ttactatgat ggatcagatc
    11821 aggagtcgct agagcgtaac ttcactagtg gagcttatag ttatgcccgt ctttacccta
    11881 ccagctccaa ctattctaag gttgcagaag aatacaagga caatatctat tacacacaat
    11941 caggctctgg gattgctggt ctgggtgtga atattgatcg ccaaagttac aactatactt
    12001 ctaaaactac agattcagag aaagtagcta ctaagaaggc attgcttaac aaagatttcc
    12061 gtcaagcctt gaattttgct cttgatcgct cagcttactc agctcaaatc aatggtaaag
    12121 atggagcagc tttagcagtt cgtaatttat ttgtaaaacc agactttgtt tcagctggtg
    12181 agaagacctt tggtgattta gtcgctgctc aacttcctgc ttatggtgat gagtggaaag
    12241 gtgtgaattt agctgatggg caggatggtt tattcaatgc tgacaaggcc aaggcagagt
    12301 ttgcgaaagc taagaaagct ttagaagcag acggcgttca gtttcctatt catctggacg
    12361 ttccagtaga ccaagcatca aaaaactaca tatctcgtat tcagtccttt aaacaatctg
    12421 tagaaacagt tcttggtgtt gaaaatgtcg ttgttgatat tcaacaaatg acaagtgatg
    12481 aattccttaa tattacttac tatgctgcca atgcttcatc tgaggattgg gatgtatcag
    12541 gaggagtttc atgggggcca gactatcaag acccatctac ttacctggat attttaaaaa
    12601 caactagcag tgaaactaca aaaacatatt taggatttga taatccaaat agcccttcag
    12661 tagttcaagt tggtttgaaa gaatacgata aattagttga tgaagctgcc aaagagacaa
    12721 gcgacttgaa tgtccgttat gaaaaatatg cagcggctca agcatggttg acagatagtt
    12781 cactctttat tcctgctatg gcttcttctg gtgcagcacc agtgctttca cgaattgttc
    12841 catttactgg agcttctgcg caaacaggct ctaaggggtc agatgtttac ttcaaatatt
    12901 tgaaattaca agataaagtg gtgactaagg aagagtatga aaaagctcgt gaaaaatggt
    12961 tgaaagaaaa agctgaatca aatgagaaag ctcaaaaaga attggcaagt catgtgaagt
    13021 aaataatttc taatagaact ttctctccat gaggagaagg ttcttttggg atttttaaag
    13081 gaaataatat gaaaaaatat atttttatgc gtgttttgcg gtcattggtt tcgattttct
    13141 tagtaacgac tttgacctac acgattatct ataccttggt tcctcgaaaa ttgattttca
    13201 agcaggatcc taactataat aaaattgcga caacggctga taaacgtgat aactatgaaa
    13261 atactgtgtt tgagcgtatg ggctacattg agtattacga tactaaagag ttgcaagaaa
    13321 aggcaagtag catggattct tctgtaacag tagaagcaaa tgcgaccaat aaagctattt
    13381 atgaaaagta catcaatcaa ttaggtcatg gttggacttt gggagaattt actgaaagtg
    13441 gtcaattcta tgctactcgt gaaattccaa tttttgaacg tgtttttcac ttctatgcta
    13501 acttgattga cattgaccat acaaataaaa tccaagaccc tgaaaatcca gacttgaaac
    13561 gctaccttcg ttttgaaaat gatccagcta tcggatggtc attggtcggt tcaggaacta
    13621 aacataaata tctcttgtac tttaacagtc agttcccatt tgttcatcaa aactttgtga
    13681 acttgaattt aggtgactct tacccaacct atgctaatac accagttctt caggttatta
    13741 ctcaaggtca aggacaaacc aaaactgccc aagttcagtt cccaacaggt aagaaaacgt
    13801 cttctgtaaa tatttactca agaacctaca agtcacctag tcaggctgac tctcgtgaag
    13861 tagctagcta tgggaaagat gatccttata cagcgactga aagtaattac caatatccat
    13921 ctatgattgt cagctctgct attactggtt tgattggttt ggttcttgcc tatgctcttg
    13981 ccgtgccact tggttcagcc atggctcgtt tcaagaacac ttggattgat agcctctcaa
    14041 cagggacttt gaccttcttg cttgctcttc caacgattgc cttggtttac atcgttcgat
    14101 tgattggatc atctattgcc cttccagatt cattccctat cttgggagct ggagattggc
    14161 gttcttacgt tttaccagca gtcatccttg gtttattggg tgctcctgtt acagccattt
    14221 ggattcgtcg ttacatgatt gacttgcaat ctcaagactt tgttcgtttc gctcgtgcaa
    14281 aaggtttgtc tgaaaaagaa atttcaaaca aacacatctt taaaaatgcc atggttccgc
    14341 tggtttcagg aattcctggt gccattattg gggttatcgg tggtgcaacc cttactgaaa
    14401 cagtcttcgc cttcccaggt atgggtaaaa tgttgattga ctctgtaaaa gcatctaata
    14461 actctatggt cgttggtctt gtcttcatct ttacatgtat ttctatcttc tcacgtcttt
    14521 tgggagatat ttggatgact attattgacc cacgtattaa attgactgag aaaggaggca
    14581 aataatgtct acaatcgata aagaaaaatt tcagtttgta aaacgtgacg attttgcctc
    14641 tgaaactatt gatgcgccag catattctta ctggaaatca gtgtttaaac aatttatgaa
    14701 gaaaaaatca actgtagtca tgttgggaat cttggtagcc atcattttga taagtttcat
    14761 ctacccaatg ttttctaagt ttgatttcaa tgatgtcagc aaggtaaacg actttagtgt
    14821 tcgttatatc aagccaaatg cggagcattg gttcggtact gacagtaacg gtaaatcgct
    14881 ctttgacggt gtctggttcg gagctcgtaa ctccatcctc atttctgtga ttgcgacagt
    14941 gattaacttg gttatcggtg tttttgtcgg tggtatttgg ggtatttcaa aatcagttga
    15001 ccgtgtcatg atggaagttt acaacgtcat ctcaaacatc ccacctcttt tgattgttat
    15061 tgtcttgact tactcaatcg gagctggatt ctggaatctg atttttgcca tgagcgtaac
    15121 aacatggatt ggtattgcct tcatgattcg tgtgcaaatc ttgcgctatc gtgacttgga
    15181 atacaacttg gcgtcacgta ctttgggaac accaaccttg aagattgttg ccaaaaatat
    15241 catgcctcaa ttggtatctg ttattgtgac aaccatgact caaatgcttc caagctttat
    15301 ctcatacgaa gccttcttgt ctttcttcgg tcttggatta ccgattacag tgccaagttt
    15361 gggtcgtttg atttcggatt attcacaaaa cgtaacaacc aatgcttact tgttctggat
    15421 tccattgaca acccttgtct tggtatcctt gtcccttttc gtagttggtc aaaacttagc
    15481 ggatgctagt gatccacgta cacatagata ggagtagaaa tgacaaaaga aaaaaatgta
    15541 attttgactg ctcgcgatat tgtcgtggaa tttgacgttc gtgacaaagt attgacagcc
    15601 attcgcggcg tttcccttga actagtcgaa ggagaagtat tagccttggt aggtgagtca
    15661 ggatcaggta aatctgtttt gacaaagacc ttcacaggta tgctcgaaga aaatggtcgt
    15721 attgcccaag gtagtattga ctaccgtggt caggacttga cagctttatc ttctcacaag
    15781 gattgggaac aaattcgtgg tgctaagatt gcgactatct tccaggaccc aatgactagt
    15841 ttggacccca ttaaaacaat tggtagtcag attacagaag ttattgtaaa acaccaagga
    15901 aaaacagcta aagaagcgaa agaattggcc attgactaca tgaataaggt tggcattcca
    15961 gacgcagata gacgttttaa tgaataccca ttccaatatt ctggaggaat gcgtcaacgt
    16021 atcgttattg cgattgccct tgcctgccga cctgatgtct tgatctgtga tgagccaaca
    16081 actgccttgg atgtaactat tcaagctcag attattgatt tgctaaaatc tttacaaaac
    16141 gagtatcatt tcacaacaat ctttattacc cacgaccttg gtgtggtggc aagtattgcg
    16201 gataaggtag cggttatgta tgcaggagaa atcgttgagt atggaacggt tgaggaagtc
    16261 ttctatgacc ctcgccatcc atatacatgg agtctcttgt ctagcttgcc tcagcttgct
    16321 gatgataaag gggatcttta ctcaatccca ggaacacctc cgtcacttta tactgacctg
    16381 aaaggggatg cttttgcctt gcgttctgac tacgcaatgc agattgactt cgaacaaaaa
    16441 gctcctcaat tctcagtatc agagacacat tgggctaaaa cttggcttct tcatgaggat
    16501 gctccaaaag tagaaaaacc agctgtgatt gcaaatctcc atgataagat tcgtgaaaaa
    16561 atgggatttg cccatctggc tgactaggag gaaggaaatg tctgaaaaat tagtagaaat
    16621 caaagattta gaaatttcct tcggtgaagg aagtaagaag tttgtcgcgg ttaaaaatgc
    16681 taacttcttt atcaacaagg gagaaacttt ctcgcttgta ggtgagtccg gtagtgggaa
    16741 aacaactatt ggtcgtgcta tcatcggtct aaatgataca agtaatggag atatcatttt
    16801 tgatggtcaa aagattaatg gtaagaaatc gcgtgaacaa gctgcggaat tgattcgtcg
    16861 aatccagatg attttccaag accctgccgc aagtttgaat gaacgtgcga ctgttgatta
    16921 tattatttct gaaggtcttt acaatcaccg tttatttaag gatgaagaag aacgtaaaga
    16981 gaaagttcaa aatattatcc gtgaagtagg tcttcttgct gagcacttga ctcgttaccc
    17041 tcatgaattc tcaggcggtc aacgtcaacg tatcggtatt gcccgtgcct tggtcatgca
    17101 accagacttt gttattgcag atgagccaat ttcagccttg gacgtttctg tacgtgccca
    17161 agtcttgaac ttgctcaaaa aattccaaaa agagctcggc ctgacctatc tcttcatcgc
    17221 ccatgacttg tcggttgttc gctttatttc agatcgtatc gcagttattt acaagggtgt
    17281 tattgtagag gttgcagaaa cagaagaatt gtttaacaat ccaattcacc catatactca
    17341 agccttgctt tcagcggtac caatcccaga tccaatcttg gaacgtaaga aggtcttgaa
    17401 ggtttacgac ccaagtcaac acgactatga gactgataag ccgtctatgg tagaaatccg
    17461 tccaggtcac tatgtttggg cgaaccaaac cgaattggca cgttatcaaa aaggactaaa
    17521 ctagtaatgg ttttataatt tccatgtcaa tttttatgga aattaggctc tttgtcaact
    17581 gtagtgggtt gaagtcagct aagctcgaga aaggacaaat ttcgtccttt cttttttgat
    17641 gttcaaagcg ataaaaatcc gttttttgaa gttttcaaag tttcgaaaac caaaagcatt
    17701 gcgcttgata agtttgatga gattattggt cgcttccagt ttggcattag aatagtgtag
    17761 ttgaagggcg ttgataatct tttctttatc tttgaggaag gttttaaaga cagtctgaaa
    17821 aataggatga acctgcttaa gattgtcctc gataagttcg aaaaatttct ctggttcctt
    17881 attctggaag tgaaaaagca agagctgata gagctgatag tggtgtttca agtcttccga
    17941 ataactcaaa agcttgttta aaatctcttt attggttaag tgcatacgaa aagtaggacg
    18001 ataaaattgc ttatcactca gtttacggct atcctgttgt atgagcttcc agtagtgctt
    18061 gatagccttg tgttcatggg attttcgatg aaactgattc atgatttgga cacgcacacg
    18121 actcatagca cggctaagat gttgtacaat gtgaaagcga tcaagaacga ttttagcatt
    18181 cgggagtgaa acagtctagg agactgtttc agcctgagcc tagaaatttg aaagcgaagc
    18241 tgtttagcca agtcatagta agggctaaac atatccatag taatgatttt gacgcgacat
    18301 cggacggctc tatcatattt aagaaagtga tctcggatg
//
LOCUS       DAVKEV010000042        17594 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVKEV010000042 DAVKEV010000000
VERSION     DAVKEV010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17594
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.042"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(162..365)
                     /locus_tag="VWZ68_001647"
     CDS             complement(162..365)
                     /locus_tag="VWZ68_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9372646.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(358..1440)
                     /locus_tag="VWZ68_001648"
     CDS             complement(358..1440)
                     /locus_tag="VWZ68_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU9372647.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTIFETAEFENLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     IIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1566..2348)
                     /locus_tag="VWZ68_001649"
     CDS             complement(1566..2348)
                     /locus_tag="VWZ68_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEU9372648.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2348..3691)
                     /locus_tag="VWZ68_001650"
     CDS             complement(2348..3691)
                     /locus_tag="VWZ68_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEU9372649.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(3803..5119)
                     /locus_tag="VWZ68_001651"
     CDS             complement(3803..5119)
                     /locus_tag="VWZ68_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEU9372650.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5313..6539
                     /locus_tag="VWZ68_001652"
     CDS             5313..6539
                     /locus_tag="VWZ68_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEU9372651.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGILGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            6738..8312
                     /locus_tag="VWZ68_001653"
     CDS             6738..8312
                     /locus_tag="VWZ68_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9372652.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8576..9364
                     /gene="codY"
                     /locus_tag="VWZ68_001654"
     CDS             8576..9364
                     /gene="codY"
                     /locus_tag="VWZ68_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEU9372653.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9364..9939
                     /locus_tag="VWZ68_001655"
     CDS             9364..9939
                     /locus_tag="VWZ68_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU9372654.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFSPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10021..10106
                     /locus_tag="VWZ68_001656"
     tRNA            10021..10106
                     /locus_tag="VWZ68_001656"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10055..10057,aa:Leu,seq:aag)
     gene            10389..11519
                     /gene="ugpC"
                     /locus_tag="VWZ68_001657"
     CDS             10389..11519
                     /gene="ugpC"
                     /locus_tag="VWZ68_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEU9372655.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(11666..11812)
                     /locus_tag="VWZ68_001658"
     CDS             complement(11666..11812)
                     /locus_tag="VWZ68_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372656.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            12020..12778
                     /locus_tag="VWZ68_001659"
     CDS             12020..12778
                     /locus_tag="VWZ68_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU9372657.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            12865..13377
                     /locus_tag="VWZ68_001660"
     CDS             12865..13377
                     /locus_tag="VWZ68_001660"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEU9372658.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13559..14503
                     /locus_tag="VWZ68_001661"
     CDS             13559..14503
                     /locus_tag="VWZ68_001661"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEU9372659.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14512..15189
                     /locus_tag="VWZ68_001662"
     CDS             14512..15189
                     /locus_tag="VWZ68_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEU9372660.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLIKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            15287..16045
                     /locus_tag="VWZ68_001663"
     CDS             15287..16045
                     /locus_tag="VWZ68_001663"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEU9372661.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16083..17588
                     /gene="lytC"
                     /locus_tag="VWZ68_001664"
     CDS             16083..17588
                     /gene="lytC"
                     /locus_tag="VWZ68_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEU9372662.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMIQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
BASE COUNT         5281 a         3172 c         3922 g         5219 t
ORIGIN      
        1 ccctgtgcaa tacagaacta aatccttcgg ataaattaat tgtctaactt tttggggggc
       61 agttcattct acacccacta ttatgcgttt tattgtggga agattttcct cattttctag
      121 tgaaattgaa ctttttctaa catcttttga tagatgactt cttaatcaat tatcatttcc
      181 attgttgttt cttggggttt catcccttgt ctttgataaa agcggagagc accctcgtta
      241 tcattccaga cacttagggt tagattattg cagccaattt ctttagcata atagcagaaa
      301 aatgacaata aaatagcccc tagatatttt gaaaggaaag cataggggct atatagttta
      361 atcaaaataa agcaaatctt tgctggtgct tgtaaagagg tcgaagccat ccttggtaac
      421 aacaccgcag tcttcaatac gaacaccgac tttaccaggg atatagatac ctggttcaac
      481 agagaagcac atgccttctt cgatgaccat gtcgtttcct tccatgatag atgggaattc
      541 atggacatcc ataccgatac catgcccgag acggtggttg aagtactcac cataaccagc
      601 tttttcgatg atctcacggg cagcgcggtc cacttcatga gcagtcacac ctggcttgat
      661 aaagtcaaga gcagcttgtt gggcttcaag agtcaagttg taaatatctt tcttgaattg
      721 gtctggtttg ccgacagcga ctgtacgagt catatctgac gcatagccat tgaccagaac
      781 ccccaggtca aagaggagaa gagcatcatt ttcaacctta ttagctgctg gaatgccgtg
      841 tggattcgca gcattatcac cagtcaagac catggtatca aagctcattt cgtaaccttc
      901 acgtttcatg gcaaagtcaa tttgtgcgat gatatctgtc tcagtcttat caagagaaat
      961 attgtcaaaa ccaacatgaa cagccttgtc agcataaaga cctgcaacca tcattttttg
     1021 tacttcatca gctgatttga tgaggcgcat gcgttggata cgaggagtga ggttttcaaa
     1081 ctcagcagtt tcaaaaattg ttttcaaacc atggtatttg gtcaagatga gattgtcaaa
     1141 ctcaacagcg acacgtttga agtcaagttg tggaagagca tgtttgattt tttgccatgg
     1201 attttcagaa tcgacatagc ccactactgg gaaggaaacg gtgctacttg cacgttctac
     1261 ttcaagagct gggacaaaga ggagaggttc ctgatccgct aggacaaaga ggaacatttg
     1321 gcgttcatgg ggatcactgt aaaaaccagt gaggtaattg attgtgacgg ggtcagatac
     1381 gacagcgacg tctagttttt ctgattcaag atatgttagg atttgttgta atttagacat
     1441 atgctacctt ctttctaccc ctctattttg gcaaaaaatg agagaaaatg caagggagaa
     1501 gggtaaaaga aaagacaaaa aactccgaca agataacgga gttctttgat atcattttcc
     1561 tttgtttaag aaaagtcagc cttgcttttg acgtcactgt actcttcagc gatttcttgg
     1621 ctgaggatat cctcataggc agggagttgg atatcctgac catatttctt cttgagggca
     1681 gtagtaacta ggcgataagc cagattggca ttacgagaga ggataggccc gtggaagtag
     1741 gaaccaaaga cattcttata atgaacccct tcaccgacct tttcttcgtt gtttccattt
     1801 ccatagacaa cctgtcccag cggtttttgg tcatcagaga ggaaggtacg accttggtga
     1861 ttttcaaatc catagtaggt ttcatcgaaa tcttcattgt gaatcttgat gtcaccgata
     1921 aaacggttat tggtctggtt gagcgtgtag tgtcccatga cccctagccc ttcgatacgt
     1981 tttcctgaag cttcaacata atattgaccc aatagttgga aaccaccgca gatagccaga
     2041 actacaccgt cgttttggat gtagttgtca atgctctctt ttttagcagg taggtcgtct
     2101 gcaatgatac tttgttcaaa gtcttgacca ccaccgaaaa aggcgatgtc gtagtgattt
     2161 tcatcaaagt catcatggag agaaacgatg tcaacggtca catgggctcc cagtttttca
     2221 gccacatact tgagcatgag gatgtttcca ttgtccccgt aggtattcat gagatttccg
     2281 tagaggtggg caatgttgag ctgatagggg taattgccat cttttgagga aagtgaagta
     2341 taaaccatta gttcatctcc tttctaacaa tctgacgact agccagcagt tcacgaaatt
     2401 ccagcatggc agtataagtt gccagaatat aggcatgctt gcagtcttga ttctcaatgg
     2461 tcttgagaac ttgctccaga ttactcgttt cagtgatttt ctcagctgga tagccagtca
     2521 ctcggaggcg acgagcgatt tcagaatgac gaacaccgcc agcgttgatt tcaggaatgt
     2581 ccatgtcagt gatttgttca aagtctgcat cccagatcca gctagtgtca attccatctg
     2641 catagttggc attaaggagg acagataggc taaatggata aggtgctagt ttgatcattt
     2701 cgatagcttg ggttgcaccg actggatttt taatcaagac aagggtacat tccttgtcac
     2761 cgatatgaaa ggtttcttgg cgtccaaaga cagcacggct cttgtcaaat ccctgtttga
     2821 tgagttgcga atcggcacct aggaaacggg cgatggccac agcagctagg gcgttataga
     2881 tattatagag cccgccgatt tggataccgt attcttggcc gtctatgaca aagcgagagc
     2941 gattgttggt caactcaacc agttttgtca aacgatagtc gagatcagga cgtttacatc
     3001 cacaaccttc acagatatag gcacccaagt ttgcataggt attatgctca tatttgagga
     3061 tgccttggca gtcaggacag agaatccctt cggtattgta gtgagccagt tgggctggtc
     3121 ccttttccaa gtcaaaacca aaatactcta tagggtttgg aatagttggc ttgtagaaaa
     3181 gtggactgtc tccgttaagg agaacagtag cagttggaac tttccgaatg gcatccaata
     3241 tcatgttata ggtagtatag atttcaccga aacggtccat ctggtcacgg aagatattag
     3301 taatgacaaa aagactaggc tggatatagt cacagatacg agatagactg gcttcgtcaa
     3361 tttcgaggac ggcaatattt ttcccagttt tagaagattt ggctgttagg aaggttgttg
     3421 caatccctgt aatcatgttg gcaccgcttg ggttggttag aacttgacca taaacctctt
     3481 ttaaaatgcc gacagtgagg gcagttgtca gggtttttcc atttgttcca gtgacaacga
     3541 caatctcgta gttcttagct aggttttgta aaatatcttt atcaaattga agggcgactt
     3601 tccctgggag cgtacttcca cgtccaagac ggcttaaaac gaagtgggaa gaacgcccag
     3661 caagaaggcc caaagtagtt tttaagttca tgtttctatt atatcacaaa agtatatcac
     3721 aaaagaggga aaagacagat ttggtgtttc gtagaagtaa aaacagccca aagagggctg
     3781 tcagttaaga tgagatttca acttaaatcg caaacaagtc attcaagttc tcagccaagg
     3841 ttgggtgagt gaagatttgt tttgtgaagt aagtgtaagg aatcttgttg tccatagcaa
     3901 cagtaataat gttgatgatt tcttgagaac cttctgagaa gatgcttgca ccaagaattt
     3961 cttttgtttc agtattaaca acagctttga aagctccgcg aaggtctcca tttacgtgac
     4021 cacgaggcat ggctgcaaca gggatttctt tcactgcgta tggaagtttc aaatcagctg
     4081 cttggctttc agtcaaacca acttgtgaaa gtgcaggtgt gatgaacata gtatttggca
     4141 cattgagacg gtcctcaagt gtgtagctgc catctccagc aaggtagctg taaacaacac
     4201 ggaagtcatc aagtgaaatg taagtaaatt gaagaccacc gttgacatct ccaactgcaa
     4261 agacaccagg aacgtttgtt tgacagtgtt tatctacttt aatagcgcca cgttcagtta
     4321 gttcaatatc tgtattttca agttgaagtg gttctacatt tggtttgcgt ccagttgcgt
     4381 agagaagggc gtcgaaacgg taagtttcgt cttcagttac gacaagcact tggtcaccgt
     4441 cgtttttaat ttcagtagta tggatatttt gaagcaattc aataccgtct tcttccatgt
     4501 attgtttagc aagagctgcg atggaaggtt ctgcacgagg taggaatgta tccaaggcat
     4561 ctaggactgt aaccttgctt cctagtttat tgtaaaggcc agcaaattca agaccgatat
     4621 ttccgccacc aaggactcca agtttttcag gcaatttatc caagctttgg atacctgttg
     4681 agtcaaagac gtttttgctt gtagcaagtc cagggattgg caagacgttt gaaacagcac
     4741 cagtgttgat gacgatagtt tcagcagtca attcttgttt ttcatcacca gcttggattt
     4801 cgatgacttt atttgaaagg aagtgagctt cagcatcaaa gatatcgacg ccagtaccag
     4861 caacagtcgt atagttttta ccgttgaggc gaccagtgat cgtgtttttg gtagcaatga
     4921 cttcttcaaa agacaagtct ttctcagcag caaccagcaa agttttagtt gggatacaac
     4981 cgatgttgat acaagttcca ccgtacatag ctttgctacg ttcaacgagg gcaacttttt
     5041 tgccagctga agccaattta ccagctagtg ttttaccagc tttaccaaat ccgataacga
     5101 ttaaatcata agttaacatt tagaattcct cctattcgaa ttacattcta gcacaagaaa
     5161 aaaacttttg cacaattctg ctacgaaaaa gacagaaaaa tatgaaaacg cttttcaggc
     5221 aaaaaactag taattttttg acaagcttga taaactaaaa tcctatctat ttttatataa
     5281 gatagaataa atgttcgaaa ataggaggtt ttatgaaatc gaatcgttat attattgcct
     5341 ttgctggggt cattttacac ttaatgctgg gttcgactta tgcctggagt gtttatcgta
     5401 accctattat tgaaaaaacg ggatgggatc aggcttctgt tgccttcgcc tttagtctag
     5461 caatcttttg tttgggctta tcggctgcat ttatggggcg tttggtagaa aaatttggtc
     5521 cgagagtcat ggggagtcta tctgcttttc tatacgcagg tggaaatatc ttaacaggat
     5581 ttgcaataga ccgtcaggaa ctgtggttgt tgtatctagc ttatggcatt ttaggtgggc
     5641 ttggtttggg agcaggctat attacccctg tgtcaacgat tataaaatgg tttcctgata
     5701 aacgtggtct cgcaacaggt ttagcgatta tggggtttgg ttttgcttct ttattgacta
     5761 gtcccatagc gcaacatctc atcgcagggg tagggcttgt agaaactttt tatattttag
     5821 gtgcaagtta ctttattatc atgctcctag cttcacaatt cattaagcgt ccaaatgagc
     5881 aagagcttgc aattttatct gcttcaggga aagaaaaaac agactctctg acgcaaggga
     5941 tgactgcaaa tcaggctcta aaaagcaatc ggttttatat gctttggatt attttcttta
     6001 tcaacatagc ttgtggttta ggcttaattt cagcggcatc gccaatggca caggagatgg
     6061 ctggcttgtc tacaagtcat gcagcagtaa tggtgggtat tttggggatt ttcaatggat
     6121 ttggtcgctt gctctgggcg agtttgtctg actatatcgg tcgccctcta acctttagta
     6181 tattactgct tgtcaatctt ttcttttctc tctcactttg gctctttaca gattccgttt
     6241 tatttgtagt tgctatgtct attttgatga cttgctatgg agctggtttt tctttgattc
     6301 cagcttatct cagtgatatt tttggaacca aggaattggc cgctctgcat ggttatattt
     6361 taacagcttg ggcaatggct ggtttagcgg gacctatttt attagcagag acttataaaa
     6421 tggctcattc gtacacacaa accttgttcg tttttctcat tttatacagt atcgccttgg
     6481 ctttgtctta ttatctaggt cgttcaatca aaaaagaaag tcaaaaaccg cttacatgat
     6541 tttctgtaga aatggggcta tcttttgctc tggtcttgtg ttatactaga taggttgcaa
     6601 agaaaacagt acttttcttt tgtggaaaag aagcaacacg attttatatc tagttatatg
     6661 aaaatacgtc ataaaaagaa aagtataaac taagccctat agggtggctt cgcaccacct
     6721 ttagaaagaa gaataacgtg aaatttaatg aattaaactt gtctgctgat ttgctagcag
     6781 aaattgaaaa agctggtttt gtagaagcta gtcctatcca agaacaaact attcctttgg
     6841 cccttgaagg caaggatgtt atcggtcaag ctcagactgg tacaggaaaa actgcagcct
     6901 ttggcttgcc tacccttgaa aaaatccgta cagaagaagc gactatccaa gctttggtca
     6961 tcgctccaac tcgtgaacta gctgtccaaa gtcaagaaga actcttccgc tttggtcgta
     7021 gtaagggagt caaagtccgt tcagtatatg gcggatcaag cattgaaaaa caaattaagg
     7081 ctcttaaatc tggtgcccat atcgtggtgg gaactccagg tcgcctcttg gacttgatta
     7141 aacgcaaggc cttgaaatta caagacattg aaacccttat ccttgacgaa gcggatgaaa
     7201 tgcttaacat gggcttcctt gaagacatcg aagccattat ttcccgtgta cctgagaacc
     7261 gtcaaacttt gcttttctca gcaactatgc cagatgccat caaacgtatc ggtgttcagt
     7321 ttatgaaagc ccctgaacat gtcaagattg cggctaagga attgacaaca gaattggttg
     7381 accagtacta tatccgtgtt aaggaacaag aaaaatttga caccatgact cgtctcatgg
     7441 atgtggcaca accagaactc gctattgtat ttggtcgtac caaacgccgt gtggatgaat
     7501 tgactcgtgg tttgaaaatt cgtggcttcc gtgcagaagg aattcatggc gacctagacc
     7561 aaaacaaacg tcttcgtgtc cttcgtgact ttaaaaatgg caatcttgat gttttggttg
     7621 cgacagacgt tgcagcgcgt ggtttggata tttcaggtgt gacccatgtc tacaactacg
     7681 atattccaca agatcctgag agttatgttc accgtatcgg tcgtacaggt cgtgctggta
     7741 agtcaggtca atctattact tttgttgctc caaacgaaat gggttacctt caaatcattg
     7801 aaaacttgac taagaaacgc atgaaaggtc tcaaacctgc aagtgtagaa gaatccttcc
     7861 aatcaaaaaa acaggtagct ctcaagaaaa tcgaacgtga ttttgcagat gaaaccattc
     7921 gtgccaactt tgagaaattt ggtaaggatg ctcgcaaatt ggctgctgag tttactccag
     7981 aagaattggc aatgtatatc ttgagtctga cagtccaaga cccagatagc cttccagaag
     8041 tggagattgc acgtgaaaaa ccactaccgt ttaaaccatc aggtaatggt ttcggtggta
     8101 aagctaaggg aggtcgtgga ggccgtcgtg gggacgaccg tcgagagcgt gatcgccgtg
     8161 gcaatggtcg ccgtgatgag ttcaaaaaag gaagtcgtgg caacgatcgt tttgataagg
     8221 aaaaacgtta ccgtaaggat aataaaaaac cacgcaatac tttaagcgaa aagcaaacag
     8281 gctttgttat tcgtaacaag ggcgataaat aagaaaaagc ggttcaaaat gaatcgcttt
     8341 tttatataag gagaccgaat gtgaaaagac aaataaaatt attatattat cttttataat
     8401 gttatgatac acaaaaatag gcaacttgtc aatagaaaag gaacaattta attaaaaata
     8461 ttctggtttt taattaaatt gtaagtcaat gcaagtcaat aaggaatttt cagataatta
     8521 ttgaaaaaga gacgttttta tgttataatg atagcgatta aattcgaggt gaaaaatggc
     8581 acatttatta gaaaaaacta gaaaaattac atcaattttg aaacgctcag aggagcagtt
     8641 gcaggatgag cttccttaca acgctattac gcgtcagtta gcggatatta ttcattgcaa
     8701 tgcctgcatt atcaatagta agggacgtct gcttggctat tttatgcgtt ataaaacaaa
     8761 tacagatcgc gtagagcaat tcttccaaac taagattttc ccagatgact acgttcaagg
     8821 ggctaatatg atttacgaaa cagaagcaaa cttgcctgtt gagcatgata tgagtatttt
     8881 ccctgttgag agtagagatg attttccaga tggcttgacg actattgcac cgattcatgt
     8941 atcggggatt cgccttggtt ctttgattat ttggcgtaat gataaaaaat tcgaagatga
     9001 ggacttggtt cttgttgaga ttgccagtac cgttgttggg attcagcttc ttaacttcca
     9061 acgtgaagaa gatgagaaaa atattcgtcg tcgtactgct gtcaccatgg cggtcaatac
     9121 cctttcttac tccgaactcc gtgctgtttc agcaatttta ggggaattaa atggaaatga
     9181 agggaagttg actgcgtcag tgattgcaga tcgtatcgga atcactcgct ctgtgattgt
     9241 caatgctctt cgtaaacttg agtctgcggg gattattgaa agtcgctcac ttggaatgaa
     9301 gggaacctat cttaaggtct tgatttcaga tatttttgaa gaagtgaaga aaagagatta
     9361 ctaatgacaa aggctttaat ttcgattgat tatacagaag attttgttgc tgatagtggg
     9421 aaactaacag caggtgctcc agctcaggcg atttcggatg ccatcagcaa ggtaactcga
     9481 ttagcttttg aacgaggaga ttatatcttc tttactattg atgctcatga agaaaacgat
     9541 tgtttccatc cggaaagtaa gttattttct cctcataatc tgattgggac gagtggacgg
     9601 aatttatatg gagatttggg gatcttttat caagagcatg gttcagacag tcgtgtcttt
     9661 tggatggata aacgccatta ctcagctttt tcagggactg acctagatat tcgtttgaga
     9721 gagcgtagag tgtctaccgt tatcttaaca ggtgtcttga cggatatctg tgtcctacat
     9781 acagctatag atgcctataa tctaggatat gacatcgaga ttgttaaacc agctgttgct
     9841 tccatctggc ctgaaaatca tcaatttgcc ctaggtcatt tcaaaaatac actcggagct
     9901 aagttagtag atgaaaatct aaatgaactt tctgagtaac ctggttggtg aaaatgaaaa
     9961 aatttgaaaa aaagtgttga caagcatccc aaaagttgat atactagtaa agtaatcgat
    10021 gcggggatgg cggaattggc agacgcgcag gactaaggat cctgtgaccg ctttaggtcg
    10081 tgagggttca agtccctctc tccgcatagg aaaagagtta gctaaagcta gctcttttgt
    10141 atttctctaa aaaattagaa tccagtcaaa tgtagtggag aatcagcgaa aatatgggaa
    10201 aactgatcct tgtttctgct tttgtcatag aagaataata aagattatct tcttcaaatt
    10261 ctccgatatt ctctaaagtt ttgtgcaagt tgcacagaac ttttttattt ttttggtcat
    10321 cttgccatag aaatataaag cgttttcatc tataatataa ttatcaaaag acaaaaggag
    10381 ttcacctcat ggtagaattg aatcttaaaa atatttacaa aaaatatcca aacagcgaac
    10441 actattcagt tgaagatttc aacttgaaca tcaaagataa agaatttatc gttttcgtag
    10501 gaccttcagg atgtggtaaa tcaactacac tccgtatgat tgctggtctt gaagacatta
    10561 cagaaggtac tgcatctatc gatggcgtgg ttgtcaacga cgtagctcca aaagaccgtg
    10621 atatcgccat ggtattccaa aactacgctc tttacccaca catgactgtt tatgacaaca
    10681 tggctttcgg tttgaaattg cgtaaataca gcaaagaaga cattaacaaa cgtgttcaag
    10741 aagcagctga aatacttgga ttgaaagaat tcttggaacg taaaccagct gacctttcag
    10801 gtggtcaacg tcaacgtgtt gccatggggc gtgcgattgt ccgtgatgcg aaagtattct
    10861 tgatggacga acctttgtca aacttggatg ccaaacttcg tgtatcaatg cgtgctgaaa
    10921 tcgctaaaat tcaccgtcgt atcggagcta caactatcta tgtaactcac gaccaaacag
    10981 aagcgatgac acttgcagac cgtatcgtta ttatgtcagc tactaagaac cctgctggta
    11041 caggtactat cggacgtgta gaacaaatcg gtactcctca agaagtttac aaaaatccag
    11101 ttaacaaatt cgttgcagga ttcatcggaa gcccagctat gaacttcatc accgtgaaat
    11161 tggttggtag cgaaattgtt tctgacggtt tccgtttgaa agtgccagaa ggagcattga
    11221 aagttcttcg tgaaaaaggc tacgaaggaa aagaattgat ctttggtatc cgtccagaag
    11281 acgtgaatgc agaacctgct ttccttgaaa cattcccaga ctgtgttgta aaagcgacta
    11341 tctctgtatc agaactgctt ggttcagaat ctcaccttta ctgccaagtt ggtaaagacg
    11401 agtttgttgc aaaagttgat gctcgtgact acttgcaaac aggtgcaaca gttgagcttg
    11461 gatttgactt gaacaaagca cacttcttcg atgtagaaac tgaaaaaaca atctactaaa
    11521 ataaataaaa ttcaaagcac tacaagaaaa gatatctctt tatcaattgt agtggagaga
    11581 tatcagttaa tctagggaga gaaacaaaat gcttctctcc tttttgctag ggaagtcata
    11641 ttatgcatct atattgtgat gctctttaat actcttcgaa aatctcttca aaccacgtca
    11701 acgtcgcctt gccgtacgta tgattactga tttcgtcagt tttatctgca acctcaaaga
    11761 tgtactttga gcagcttacg gctagtttcc tagtttgctc tttgatttcc attgagtatt
    11821 atttgtgggt accatctaca agtgaagcta tatgcgtaaa ctacgtgagc aattgaattc
    11881 gaactagaga ggtaataata aatttatgct atagttatgg tgacttgtat gcttttgatt
    11941 ctagtttatc aaataataga ttagaattgt cagataatat cattttgtgt tataatgaag
    12001 aaaaaacaga ggtgttcaaa tgtcagaagc aggtcataag tttttagcaa aattggggaa
    12061 aaaacgctta cgtccaggtg gaaagcgtgc cacagattgg ttaattgcag aaggaggatt
    12121 ttcaaaagaa aagagaatac tagaggttgc gtgtaatagg ggaactacag caattgagtt
    12181 ggcacagcgt tttggttgca agataactgc tgttgatatg gatgctcaag ctttagaagt
    12241 ggctaaaaaa tctgctggaa cggcaggtgt tgctcattta atcagttttg aaagagcaaa
    12301 tgcaatgaaa cttccttatc aagatgctag ttttgatatt gttataaatg aagctatgct
    12361 gactatgcaa gccgatcaag ctaagaaaaa atgtgtaatg gaatatctaa gggtattaaa
    12421 acctggaggt cttctcttga cacatgatgt gcttcttaag gaagctaaag agtctatcag
    12481 acaggaatta tcacaagcaa ttcatgtaaa tgtaggtcct ttaactcaag atggttggga
    12541 acaggtgatg atagaatcag gttattgtga tgtgaaagca ttgactggtg aaatgacatt
    12601 aatgaaatta tcgggtatga tttatgacga aggtttgcta ggaactttga aaatttgtgt
    12661 aaatgcttgt aaaaaggaga atagaaagca gtttttaact atgtataaaa tgtttgctaa
    12721 gaataaacag aaattgggct ttattgcgat ggctagttat aaatcgtcaa aacgttagat
    12781 aattattgaa gttaactttt ccttttttct ttcttaaaaa atatgctata atagagagta
    12841 aaaaactttg aaagaaagaa aaagatgaat ttaaaagatt acattgcaac aattgaaaat
    12901 tatccaaagg aaggcattac cttccgtgat attagtcctt tgatggctga tggaaatgct
    12961 tatagctacg ctgttcgtga aatcgttcag tatgctactg acaagaaagt cgacatgatc
    13021 gtgggacctg aagctcgtgg atttatcgtg ggttgtccag ttgcctttga gttgggaatt
    13081 ggttttgcgc ctgttcgtaa gccaggtaaa ttgccacgcg aagttatttc tgctgactat
    13141 gaaaaagagt acggtgtcga taccttgact atgcacgcgg atgccattaa gccaggtcaa
    13201 cgtgttctta ttgtagatga ccttttggcg acaggtggaa ctgttaaggc aactatcgag
    13261 atgattgaaa aacttggtgg tgttatggca ggttgtgcct tccttgttga attggatgaa
    13321 ttgaacggcc gtgaaaaaat tggtgactac gactacaaag ttcttatgca ttattaatga
    13381 aaacagtccc tagggctgtt ttctctacac taggatataa aaatagacta taactagtta
    13441 gagaaaaact ataattgaaa actatatctt cttgcagtat aataaaagga ctaagtgttt
    13501 gagatttgtc ttcaaacata tgcaattatt cctgaaagag tacagttagg agagggttat
    13561 gccgattcga attgataaaa aattgccagc tgttgagatt ttacggacag agaatatctt
    13621 tgtcatggat gatcaacgtg ctgcccacca agatatccgt cctttgaaga ttttaatttt
    13681 aaatctcatg ccacagaaaa tggtcacaga gacccagttg ttgcgccact tggctaatac
    13741 acccctacaa ctggatattg attttctcta tatggagagc caccgttcta aaacaactcg
    13801 ttcagagcac atggagacct tctataaaac ttttcctgaa gtcaaggatg agtattttga
    13861 tgggatgatc atcacgggtg ctccagttga gcatttacca tttgaggaag tggactattg
    13921 ggaggaattt agacagatgc ttgagtggtc taagactcat gtctattcga cccttcatat
    13981 ctgttggggg gctcaggctg ggctttatct gcgctatggt gtagaaaaat accagatgga
    14041 cagtaagcta tcaggtattt atcctcagga caccctaaaa gagggtcacc ttctatttag
    14101 aggctttgat gatagctatg tatcccctca ttcacggcac acggagattt ctaaggaaga
    14161 ggtcttaaac aagaccaatc tcgagatttt atcagaagga cctcaggttg gggtttctat
    14221 tttggccagt cgtgatttac gagaaattta tagttttggt catttggagt atgaccgtga
    14281 taccttggca aaagagtatt ttcgagatcg tgatgcaggt ttcgacccac atattccaga
    14341 aaattacttt aaagatgatg atgttaatca ggtaccttgt ctttgttggt cttcatctgc
    14401 agccctcttt ttcagtaatt gggtaaacca tgcggtctat caggagacgc cttttgattg
    14461 gagaaagata gaagatgatg catctgcata tgggtattta taagaggaat tatgacatat
    14521 ttagacgctt ttaaatcagg taccttggtt ttaccgagtg ccctgctctt gcattttaag
    14581 gaactctttc cttctagcga cgattttctg gtttggcaat ttttctattt gcaaaatacg
    14641 acaggcttag aagaaatgtc gccaagccag attgctgaaa ggattggcaa ggaaatttcg
    14701 gatgtcaacc agtccatttc taatctgacg gaaaggggac tgctccagta tcgtactatc
    14761 gaattaaatg gcgaaattga attgctcttt gatgctagtt tggccttgga acgtttggat
    14821 gacctgtttg gagcagttcg ttcaagttca gaccagctaa cacctcaaaa ccagctcaag
    14881 gatttggtgg aaaccttcca gcaggagttg ggacgattgt tgacgccttt tgagattgag
    14941 gatttgatca agacactaaa ggaagatgga accagtgctg acttgattaa ggaggctctt
    15001 cgtgaagctg ttttgaatgg aaaaccaaac tggaagtaca ttcaggcgat tttgagaaac
    15061 tggcgccatg aaggaatcaa gagtgtggct caaattgagg ccaagagagc agaaagagaa
    15121 gcaagcaatc ctcagttgac acaggtatct gcagatttca gaaatgccat ggatctctgg
    15181 aaggattaat ccatgcaagt aggcttgaaa tccgagtaag atttgcaagc tgtgtataat
    15241 tgtgatagaa taaatagaaa ataaattgaa aaaagaggta tgtgaaatgt cacgtaaacc
    15301 atttatcgct ggtaactgga aaatgaacaa aaatccagaa gaagctaaag cattcgttga
    15361 agcagttgca tcaaaacttc cttcatcaga tcttgttgaa gcaggtatcg ctgctccagc
    15421 tcttgatttg acaactgttc ttgctgttgc aaaaggctca aaccttaaag ttgctgctca
    15481 aaactgctac tttgaaaatg caggtgcttt cactggtgaa actagcccac aagttttgaa
    15541 agaaatcggt actgactacg ttgttatcgg tcactcagaa cgccgtgact acttccatga
    15601 aactgatgaa gatatcaaca aaaaagcaaa agcaatcttt gcgaacggta tgcttccaat
    15661 catctgttgt ggtgaatcac ttgaaactta cgaagctggt aaagctgctg aattcgtagg
    15721 tgctcaagta tctgctgcat tggctggatt gactgctgaa caagttgctg cctcagttat
    15781 cgcttatgag ccaatctggg ctatcggtac tggtaaatca gcttcacaag atgatgcaca
    15841 aaaaatgtgt aaagttgttc gtgacgttgt agctgctgac tttggtcaag aagtcgcaga
    15901 caaagttcgt gttcaatacg gtggttctgt taaacctgaa aatgttgctt catacatggc
    15961 ttgcccagac gttgacggtg cccttgtagg tggtgcgtca cttgaagctg aaagcttctt
    16021 ggctttgctt gactttgtaa aataatcagt aagtagcaaa agctaggtgg aacagcattc
    16081 agatgtctgt tacatttttt ataggagagg aaagattgaa aataaaaatt ggattagcaa
    16141 gtatctgttt actaggcttg gcaactagtc atgtcgctgc aaatgaaact gaagtagcaa
    16201 aaacttcgca ggatacaacg acagcttcaa gtagttcaga gcaaaatcag tcttctaata
    16261 aaacgcaaac gagcgcagaa gtacagacta atgctgctgc ccactgggat ggggattatt
    16321 atgtaaagga tgatggttct aaagctcaaa gtgaatggat ttttgacaac tactataagg
    16381 cttggtttta tattaattca gatggtcgtt actcgcagaa tgaatggcat ggaaattact
    16441 acctgaaatc aggtggatat atggcccaaa acgagtggat ctatgacagt aattacaaga
    16501 gttggtttta tctcaagtca gatggggctt atgctcatca agaatggcaa ttgattggaa
    16561 ataagtggta ctacttcaag aagtggggtt acatggctaa aagccaatgg caaggaagtt
    16621 atttcttgaa tggtcaagga gctatgatac aaaatgaatg gctctatgat ccagcctatt
    16681 ctgcttattt ttatctaaaa tccgatggaa cttatgctaa ccaagagtgg caaaaagtgg
    16741 gcggcaaatg gtactatttc aagaagtggg gctatatggc tcggaatgag tggcaaggca
    16801 actactattt gactggaagt ggtgccatgg cgactgacga agtgattatg gatggtgctc
    16861 gctatatctt tgcggcctct ggtgagctca aagaaaagaa agatttgaat gtcggctggg
    16921 ttcacagaga tggtaaacgc tatttcttta ataatagaga agaacaagtg ggaaccgaac
    16981 atgctaagaa aatcattgat attagtgagc acaatggtcg tatcaatgat tggaaaaagg
    17041 ttattgatga gaacgaggtg gatggtgtca ttgttcgtct aggttatagc ggtaaagaag
    17101 acaaggaatt ggcgcataac attaaggagt taaaccgtct gggaattcct tatggtgtct
    17161 atctctatac ctatgctgaa aatgagaccg atgctgagaa tgacgctaaa cagaccattg
    17221 aacttataaa gaaatacaat atgaacctgt cttaccctat ctattatgat gttgagaact
    17281 gggaatatgt aaataagagc aagagagctc caagtgatac agacacttgg gttaaaatca
    17341 tcaacaagta catggacacg atgaagcagg cgggttatca aaatgtatat gtctatagct
    17401 atcgtagttt attacagacg cgtttaaaac acccagatat tttaaaacat gtaaactggg
    17461 tagcggccta tacgaatgct ttagaatggg aaaaccctta ttattcagga gaaaaaggtt
    17521 ggcaatatac ctcttctgaa tacatgaaag gaatccaagg gcgcgtagat gtcagcgttt
    17581 ggtattaagc gatg
//
LOCUS       DAVKEV010000043        17546 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVKEV010000043 DAVKEV010000000
VERSION     DAVKEV010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17546
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.043"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..738
                     /locus_tag="VWZ68_001665"
                     /pseudo
     CDS             1..738
                     /locus_tag="VWZ68_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(802..1884)
                     /locus_tag="VWZ68_001666"
     CDS             complement(802..1884)
                     /locus_tag="VWZ68_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9372663.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(1881..2858)
                     /locus_tag="VWZ68_001667"
     CDS             complement(1881..2858)
                     /locus_tag="VWZ68_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU9372664.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            3073..3450
                     /locus_tag="VWZ68_001668"
     CDS             3073..3450
                     /locus_tag="VWZ68_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU9372665.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            3685..5076
                     /locus_tag="VWZ68_001669"
     CDS             3685..5076
                     /locus_tag="VWZ68_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEU9372666.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            5190..6032
                     /locus_tag="VWZ68_001670"
     CDS             5190..6032
                     /locus_tag="VWZ68_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEU9372667.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERENLKTIAVQSGAPRVD
                     DVDF"
     gene            6305..7066
                     /locus_tag="VWZ68_001671"
     CDS             6305..7066
                     /locus_tag="VWZ68_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU9372668.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            7259..8176
                     /gene="glyQ"
                     /locus_tag="VWZ68_001672"
     CDS             7259..8176
                     /gene="glyQ"
                     /locus_tag="VWZ68_001672"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEU9372669.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            8388..10424
                     /locus_tag="VWZ68_001673"
     CDS             8388..10424
                     /locus_tag="VWZ68_001673"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEU9372670.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            10466..10723
                     /locus_tag="VWZ68_001674"
     CDS             10466..10723
                     /locus_tag="VWZ68_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEU9372671.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(10946..12190)
                     /locus_tag="VWZ68_001675"
     CDS             complement(10946..12190)
                     /locus_tag="VWZ68_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU9372672.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AFTGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(12209..12814)
                     /locus_tag="VWZ68_001676"
     CDS             complement(12209..12814)
                     /locus_tag="VWZ68_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU9372673.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFTDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            complement(12874..13797)
                     /locus_tag="VWZ68_001677"
     CDS             complement(12874..13797)
                     /locus_tag="VWZ68_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEU9372674.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            14091..15470
                     /locus_tag="VWZ68_001678"
     CDS             14091..15470
                     /locus_tag="VWZ68_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU9372675.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALAGGKIELFRNGAF
                     LVDKKQETSIPDVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            15622..16497
                     /gene="pdxS"
                     /locus_tag="VWZ68_001679"
     CDS             15622..16497
                     /gene="pdxS"
                     /locus_tag="VWZ68_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEU9372676.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            16498..17082
                     /gene="pdxT"
                     /locus_tag="VWZ68_001680"
     CDS             16498..17082
                     /gene="pdxT"
                     /locus_tag="VWZ68_001680"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEU9372677.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEDVEILATVDNQIVA
                     AQEKNMLVTSFHPELTDDAHLHQYFIEMCKEKRQ"
BASE COUNT         5336 a         3195 c         3849 g         5166 t
ORIGIN      
        1 ggcaggagaa tttgttacaa taccttattt caggcttata tcgttcctac acacgtgatg
       61 ccttctatca actgttgaag caccatggtt ggcgaaatat tatgccacgt ccagaacatc
      121 ctaggaaagc agacgctcaa accattgtcg cgtctaaaaa taaaatctca attcaagaag
      181 acaagaaagc gctttaaaac cagtagacct tttcataagg ttcgcttgat gtaccaagat
      241 gaggctggtt tcggtagaat cagtaaactg ggatcttgtt ggtctccaat aggagtaggt
      301 ctacatgtcc atagtcacta tatacgagaa tttcgctatt gttatggagc tgttgatgcc
      361 tatacaggcg aatcattttt cttaatagct ggtggatgta atactgagtg gatgaacgcc
      421 tttttagaag agctttcaca agcttatcca gatgattatt ttttactcgt tatggacaat
      481 gctgtatggc ataaatcaag taccttaaag attccgacta atattggctt tgcatttatt
      541 cctccataca caccagagat gaaccccatt gaacaattgt tgaaagagat tcgtaaacgt
      601 ggatttaaga ataaagcctt tcgaactttg gaagatgtca tgaatcaact ccaagatgtc
      661 atacaaggac tggagaagga ggtgataaag tccatcgtta atcggagatg gaatagaatg
      721 ctttttgaaa gcagatgagt ataaaattga attgcttata aaaaagctcc atacactgga
      781 tgtgtataga gcaatggggc tttatttgat atagagttct tggtttttta ggacaatttc
      841 tcggatactt gcaaactttt taagtttttt gatttcttct ggatgagtga cgagagtaat
      901 aacatatcct tccttgccca tacggccagt acggccagca cggtgtgtgt aggtttcgct
      961 atctctagga atatcaaagt ttacgacaca ttctaggcta tcgatatcaa ttccacgagc
     1021 caaaaggtca gttgcaagaa gcagggttag ttggttatct ttaaactttt ctaagatgat
     1081 ttttctaaat ttaacattaa catcactagc gagggaaaca gccaatatat cacgatactg
     1141 tagtttttcc tcggcattcc caaggtctga caggctattg aagaagacta gaccacggaa
     1201 atcctctaca tgagccagtt ttcgcagcat atccactcga tgacgttggt ctacctgcat
     1261 gtagaaatgc tggatattgt ccaatttttg atcagagaga tcaatagtgc gtgtattcgg
     1321 cacaatcttt tcttggtcaa acttggtcgt ggcactcatg tagaccagtt ggtggtcacg
     1381 aggtgcgtag tgagtgattt tttctacaaa gtgaatctga gaatcatcta gtaattggtc
     1441 aaattcatcc aggatgatgg tttccacatt catcatcttg atttttttaa gtttaatgag
     1501 ttcaaagata cggccaggag ttccaatcag aatttctggc ccctttttaa gacgttcaat
     1561 ttgtcgtttc tgacttgaac ctgaaaggaa gagttgagca gtcaatccga tagcttctgc
     1621 ccacgtttta catacatcaa aaatctgtcc agcaagttcc gtatttggtg ctagaatcaa
     1681 gagttgttgg gcttttttct tttgtagtct gagaagactt ggtaggagat acgctagggt
     1741 cttaccagtt ccggtttggc tcactcctag gaggttttct ccagcaagaa ggggctcaaa
     1801 tagttgagtt tgaatggggg tgaattcttg gaaaccgagt tggtcactca gttcttgcca
     1861 ttcagtcggt agtttggttt tcatttttct gcctcaaatc taatgccagc agtctggcgc
     1921 atggtatata gtagctcatg aacagagcct gcatcataca gccaagtttg gtagagattc
     1981 agatctggtt gctggatcat gtgtgcaaat gcagcgactt cctcagtcat cgtatgagga
     2041 gcctgttgga taggaagctg gacttgattt ccttggtggt cggtaaaaat agctgagcga
     2101 atatgctcaa tcgtgttgag agtcaaggtt ccatctgttg tataaatctc gcaaggaaga
     2161 ttggaagtga tgttttttcc agccttgatg tgaacttgat agtctgggta gaagaggata
     2221 ccatctccat ttaggtcaat gctattgtca agctgttgag catggtaagt cgcgtcatta
     2281 gctttttcaa aaagacgaac agcagcatag aggggataaa tccccaaatc catgagggct
     2341 ccaccagcaa aacggtctga aaagacattt ggtgtttgtc cagccaacaa gtcaggcatc
     2401 ttggaagagt atttggcata gttgaaatct gctcctaaca cttgcttatc tgctaaaaag
     2461 tttttgatag tagtaaaggc tttctcgtgg taattacgag ctgcttcaaa gataaaacag
     2521 ttattttttt cagctgtttg aatcaaatca aaccattctt gtggttgagt gacagctggc
     2581 ttttcgagaa taacatgttt accagcagac aaggcagctt ttgcctgagc aaaatgtaag
     2641 gagtttggac tggcgatata gactaaatca aaagaagatt tgaagaagac ttctaattga
     2701 tcgaatagtt ggatattctg atagcgagaa gcaaaggttg ctgcagtttc tagttttcta
     2761 gaatagattg cgaccagttg gtattctcca ctggtatggg ctgcttctat gaaatgatgg
     2821 ctgatagcgc cagttccgat gacacctaat tttagcataa atactccttt tccgatttta
     2881 aatccttctt tcattataac atagatagac gggactatcc aacagagagg agaaaatttc
     2941 aaataagcta ttagctttct tttccgaata aatagataga agcatagaat ctagcaaacc
     3001 tagatttaaa aatgtgctat aatagaagga ggaaaaggag gattctcaga catccaggta
     3061 tcagcccaac taatgatttg tcaatttatc cgcgatatgc tggacttgcc agcaaaaaat
     3121 gtgacgattt tggagggaag taacattcac gtcttgcctt ccatgcccta ctcagcgcaa
     3181 gatttctata ctagtataga cgtcttggcg gagttagata atggaatcca agttatcatc
     3241 gaaattcagg ttcatcatca gaattttttc atcaatcgcc tatgggctta tctgtgcagt
     3301 caggttaatc aaaacctaga aaaaattcgc caacgtgaag gtgataccca ccagagctac
     3361 aaacaaatcg caccagtata cgctatcgca attgtcgata gtaattactt ctcagatgac
     3421 ctagcttttc atagttttat agtaaaatga aatgagaaca ggacaaatcg atcaggacaa
     3481 tcaaatcgat ttctaacaat gttttagaag tataggtcta ctattctagc ttcaatctac
     3541 tagaaattcc atagatataa aactacataa tctctacaga tacggatgtt ggagttgatg
     3601 taagatgctt tggcttgcta gaggaattgt ggattgccaa attgtatcat tgaaattatt
     3661 gctcaaattt gttatgatat aaatatgaat aaaagtagac taggacgtgg cagacacggg
     3721 aaaacgagac atgtattatt ggctttgatt ggtattttag caatttctat ttgcctatta
     3781 ggcggattta ttgcttttaa gatctaccag caaaaaagtt ttgagcaaaa gattgaatcg
     3841 ctcaaaaaag agaaagatga tcaattgagt gagggaaatc agaaggagca ttttcgtcag
     3901 gggcaagccg aagtgattgc ctattatcct ctccaagggg agaaagtgat ttcctctgtt
     3961 agggagttga taaatcaaga tgttaaggac aagctagaaa gtaaggacaa tcttgttttc
     4021 tactatacag agcaagaaga gtcaggttta aagggagtcg ttaatcgtaa tgtgaccaaa
     4081 caaatctatg atttagttgc ttttaaggtt gaagagactg aaaagaccag tctaggaaag
     4141 gttcacttaa cagaagatgg ccaacctttt acacttgacc aactgttttc agatgctagt
     4201 aaggctaagg aacagctgat aaaagagttg acctccttca tagaggataa aaaaatagag
     4261 caagaccaga gtgagcagat tgtaaaaaac ttctctgacc aagacttgtc tgcatggaat
     4321 tttgattaca aggatagtca gattatcctt tatccaagtc ctgtggttga aaatttagaa
     4381 gagatagcct tgccagtatc tgctttcttt gatgttatcc aatcttcgta cttactcgaa
     4441 aaagatgcgg ccttgtacca atcttacttt gataagaaat atcaaaaagt tgtcgctcta
     4501 acctttgatg atggtccaaa tccagcaacg accccgcagg tattagagac cctagctaaa
     4561 tatgatatta aagcgacttt ctttgtgctt gggaaaaatg tttctgggaa tgaggacttg
     4621 gtgaagagga taaaatctga aggtcatgtt gttggaaacc atagttggag ccatccgatt
     4681 ctctcgcaac tctctcttga tgaagctaaa aagcagatta ctgatactga ggatgtgcta
     4741 actaaagtgc tgggttctag ttctaaactc atgcgtccac cttatggtgc tattacagat
     4801 gatattcgca atagcttgga tttgagcttt atcatgtggg atgtggatag tctggactgg
     4861 aagagtaaaa atgaagcatc tattttgaca gaaattcagc atcaagtagc taacggctct
     4921 atcgttttga tgcatgatat tcacagtccg acagtcaatg ccttgccaag ggtcattgag
     4981 tatttgaaaa atcaaggtta tacctttgtg accataccag agatgctcaa tactcgccta
     5041 aaagctcatg agctgtacta tagtcgtgat gaataagcaa gaaaaaatag gtctgttaga
     5101 tatttgacag acttattttt tacagaagat agtactactt aaaaaatgtt ttatgctata
     5161 attgatgaat aaaatagaag gagaagcata tgaataccta tcaattaaat aatggagtag
     5221 aaattccagt attgggattt ggaactttta aggctaagga tggagaagaa gcctatcgtg
     5281 cagtgttaga agccttgaag gctggttatc gtcatattga tacggcggcg atttatcaga
     5341 atgaagaaag tgttggtcaa gcaatcaaag atagcggagt tccacgtgaa gaaatgttcg
     5401 taactaccaa gctttggaat agtcagcaaa cctatgagca aactcgtcaa gctttggaaa
     5461 aatctataga aaaactgggc ttggattatt tggatttgta tttgattcat tggccgaacc
     5521 caaaaccgct cagagaaaat gacgcatgga aaactcgcaa tgcggaagtt tggagagcga
     5581 tggaagacct ctatcaagaa gggaaaatcc gtgctatcgg cgttagcaat tttcttcccc
     5641 atcatttgga tgccttgctt gaaactgcaa ctatcgttcc tgcggtcaat caagttcgct
     5701 tggcgccagg tgtgtatcaa gatcaagtcg tagcttactg tcgtgaaaag ggaattttat
     5761 tggaagcttg ggggcctttt ggtcagggag aactatttga tagcaagcaa gtgcaagaaa
     5821 tcgcagcaaa tcacggaaaa tcgattgctc agatagcctt ggcctggagc ttggcagaag
     5881 gatttttacc acttccaaaa tctgtcacaa cctctcgtat tcaagctaat cttgattgct
     5941 ttggaattga actgagtcat gaggagagag aaaacttaaa aacgattgct gttcaatcgg
     6001 gtgctccacg agttgatgat gtggatttct agaaaatcat aaaaagaatt gtacattatt
     6061 ctaatttttg atataatagt cagcaggaaa gaaagtctta tggcgttctt caagcgagct
     6121 tgggatagtg ggagccaagt agggcaaaat aatgagctgg cgctttctgt agtattttca
     6181 aaaacaatga agtaataaat tagggtggaa ccgcgtttct gacgccccta ggttaaatca
     6241 acctaggatt gtcggacgcg gttcttttgc ttattcagtc tattgtgtga aagaaaggag
     6301 agccgtggac aacctttatc ttgtaaaaga cgatagtcaa ctagctacat ttcgtgattt
     6361 tgtagtaaga aatactgaaa agttgaaaga ttatcaatct tttttaaaga atgaacttgc
     6421 agtctgtgat ttaccgcaag ccgttatttg gtcagatttt aatgctgcta cacagattat
     6481 tagggaaagc gctgttccag cctatacaaa taatagacga atggttatgg cgcctgattt
     6541 agctgtttgg aaagagttgt atttgtatca attgatggac tacgagtgtt ctcagcaaac
     6601 tcaagcaata gaaagtcact atcattcttt atctgaaaat ttcctcttac agattgtagg
     6661 acatgagtta gctcattggt cggagcattt tttagatgat tttgatggtt atgactctta
     6721 tatctggttc gaagagggga tggttgaata tattagtcgc aagtatttct tgacagaaga
     6781 ggaatttcaa gcggaaaaaa tttgtaatca atctctcgta gaactttttc agaagaagta
     6841 tggttggcat tcattgaatg attttggttc ttcgacttat gataagaact atgcaagtat
     6901 tttttatgaa tactggcgca gctttttgac agtagataag ttggtagaaa atttaggtag
     6961 tgtacaagcg gtcttagatt cttatcattt atgggcaaat acagaaaaaa cttttccctt
     7021 gttagattgg tttgttcagc agaaattaat tgaaaaagaa atataaaaac taaaggagta
     7081 aacaatgtct aagaaattga catttcactg cgtcagtggc agaaacctcc ttacagtcgg
     7141 actgccccac gctcagcact agagtgcctg agctagacgc agtactaact cgtcttgcct
     7201 cgtatgatcg acgaggcaga ctcatgtcgc aagtaattta tataaaaagg agtaaacaat
     7261 gtctaagaaa ttgactttcc aggaaatcat ccttactttg caacaatttt ggaatgacca
     7321 aggttgtatg cttatgcagg cttatgataa tgaaaaaggt gcgggaacaa tgagtcctta
     7381 cactttcctt cgtgctatcg gacctgagcc atggaatgca gcttatgtag agccatcacg
     7441 tcgtcctgct gacggtcgtt atggggaaaa ccctaaccgt ctctaccaac accaccaatt
     7501 ccaggtggtc atgaagcctt ctccatcaaa tatccaagaa ctttaccttg aatctttgga
     7561 aaaattggga atcaatcctt tggagcacga tattcgtttt gttgaggaca actgggaaaa
     7621 cccatcaact ggttcagctg gtcttggttg ggaagtttgg cttgacggaa tggaaatcac
     7681 tcagttcact tatttccaac aagtcggtgg attggcaact ggccctgtga ctgcggaagt
     7741 tacctatggt ttggagcgct tggcttctta cattcaagaa gtagactctg tctatgatat
     7801 cgagtgggct gatggtgtaa aatacggaga aatctttatc cagcctgagt atgagcactc
     7861 aaaatattca tttgaaattt cggaccaaga aatgttgctt gaaaactttg ataagtttga
     7921 aaaagaagct ggtcgtgcat tagaagaagg cttggtacac cctgcctatg actatgttct
     7981 caaatgttca cataccttta atctgcttga cgcgcgtggt gccgtatctg taacagagcg
     8041 tgcaggctat atcgctcgta tccgtaactt ggcccgtgtc gtagccaaaa cctttgtcgc
     8101 agaacgcaaa cgcctaggct acccactttt ggatgaagaa acaagagcta aactcctagc
     8161 agaagacgca gaataaagag agtgacaaat tacgaaaatg ggcgaacaga gtgagccctg
     8221 agccagttgc cgcagtgatg aaggtatcct tagtgaaact aaggatacta ggcaaaattg
     8281 gagacttttg gctccaattt tagcaatgaa acaacgaagt tggttgcttg cgtgccaatc
     8341 acataaggca aactggaaaa taaaaagata cttttcggag aaaaaacatg acaaaaaact
     8401 tattagtaga actcggtctt gaagaattac cagcctatgt tgtcacacca agtgaaaaac
     8461 aactaggcga aaaaatggca gccttcctca aggaaaaccg cctgtctttt gaagccattc
     8521 aaaccttctc aacaccacgt cgtttggctg ttcgtgtgac tggtttatca gacaaacagt
     8581 ctgatttgac agaagatttc aagggaccag caaagaaaat tgccttggat agtgatggaa
     8641 acttcaccaa agcagctcaa ggatttgtcc gtgggaaagg tttgactgtt gaagatatcg
     8701 aattccgtga aattaagggt gaagaatatg tctatgtcac taaggaagaa gttggccaat
     8761 cagttgaagc cattgttcct ggtgttgtag atgtcttgaa gtcattgact ttccctgtca
     8821 gcatgcactg ggctggaaat agctttgaat acatccgccc tgttcacact ttaactgttc
     8881 tcttggatga gcaagagttt gacttggatt tccttgatat caagggaagt cgtgtgagcc
     8941 gtggccatcg tttcttgggg aaagaaacca aaattcagtc agcattgagc tatgaagaag
     9001 accttcgtaa gcagtttgta atcgcagatc catgtgaacg tgagcaaatg attgttgacc
     9061 aaatcaagga aattgaggca aaacatggtg tacgtatcga aattgatgcg gatttgctga
     9121 atgaagtctt gaatttggtt gaatacccaa ctgccttcat gggaagtttt gatgctaaat
     9181 accttgaagt tccagaagaa gtcttggtga cttctatgaa ggaacaccag cgttactttg
     9241 ttgttcgtga tcaagatgga aaactcttgc caaacttcat ttctgttcgt aacggaaacg
     9301 cagagcgttt gaaaaatgtc atcaaaggaa atgaaaaagt cttagtagcc cgcttggaag
     9361 acggagaatt cttctggcgt gaagaccaaa aattggtgat ttcagatctt gttgaaaaat
     9421 taaacaatgt caccttccat gagaagattg gttcccttcg tgaacacatg attcgtacgg
     9481 gtcaaatcac tgtacttttg gcagaaaaag ctggtttgtc agtggatgaa acagttgacc
     9541 ttgctcgtgc agcagccatt tacaagtttg acttgttgac aggtatggtt ggtgaatttg
     9601 acgaactcca aggaattatg ggtgaaaaat acacccttct tgctggtgaa actccagcgg
     9661 tggcagctgc tattcgtgaa cactacatgc ctacatcagc tgaaggagaa cttccagaga
     9721 gcaaggtcgg cgcagttcta gccattgcag acaaattgga tacgattttg agtttcttct
     9781 cagtaggatt gattccatca ggttctaatg acccttatgc ccttcgtcgt gcaactcaag
     9841 gtgtggttcg tatcttggat gcctttggtt ggcacattgc tatggatgag ctgattgata
     9901 gcctttatgc attgaaattt gacagtttga cttatgaaaa taaagcagag gttatggact
     9961 ttatcaaggc tcgtgttgat aagatgatgg gctctactcc aaaagatatc aaggaagcag
    10021 ttcttgcagg ttcaaacttt gttgtggcag atatgttgga agcagcaagt gctctcgtag
    10081 aagtaagcaa ggaagaagat tttaaaccat ctgttgaatc actttctcgt gcctttaacc
    10141 tggctgagaa ggcagaaggg gttgctacag ttgattcagc actatttgag aatgaccaag
    10201 aaaaagcttt ggcagaagca gtagaaacac tcgttttatc aggacctgca agtcagcaat
    10261 tgaaacaact ctttgcgctt agcccagtca ttgatgcttt ctttgaaaat actatggtaa
    10321 tggctgaaga tcaggctgtc cgtcaaaatc gtttggcaat cttgtcacaa ctaaccaaga
    10381 aagcagctaa gtttgcttgt tttaaccaaa ttaacactaa ataaaatttg ataaacggac
    10441 tttatcttat tacaaaggag aagaaatgga tccgaaaaaa attgctcgta tcaatgagct
    10501 tgctaaaaag aaaaaaacag aaggcttaac accagaagaa aaagtggaac aagccaaact
    10561 acgtgaggag tacatcgaag gttatcgccg cgctgttcgt caccacattg aaggaatcaa
    10621 aattgtggac gaagaaggaa acgatgttac accagaaaaa ctacgccaag tacaacgtga
    10681 aaaaggatta catggccgta gtcttgatga tccaaattca taataatact cttcgaaaat
    10741 caaattcaaa ccacgtcagc ttcaccttgc cgtacttaag tacagcctgc ggctagcttc
    10801 ctagtttgct ctttgatttt cattgagtat atgtattctt tcttttaaca aagatagatg
    10861 aaacgataac aaagagacta gcagtttgtg tttgctagtc ttttttcgct aaaaaaggaa
    10921 ccataatggt tcctaaaaac tatcattagt aacttgcacc ggctgtagcg tctgcgtcac
    10981 caccgtggcc tccagcatcc cctgaatcag aagcgccaga agtagcatcg gcgtctccat
    11041 gacctccggc agcaggagca aatggtccgc taccacccac caaacgttga ccagtctctt
    11101 ttaggtacca gtcaagccat ggttggaagt taaagacgat ttcattgata ccagcgtatg
    11161 atccatcagg atagtacatt gcttggtagt tgtgagtgtt gataacacct gcaggagaac
    11221 ctggaacgat cgtacggacg tattcttggt ttccgttgcg aagtgttccg ataacccact
    11281 ctacgttctt catacgtgct ggtggaagag aaccatgaac agtcgacata cggctacctg
    11341 attgaggtgg tacacgttta gcgaacatag tgtctggatc ttggtgagcg ttgttgtagt
    11401 agaggaattg gttgttgtcg tcagcgtatg tcaattcaaa tggcatagct ttcaagaaca
    11461 tatcaatttg gttaactgtt aggataccgt ggtccaattt gacataggta tcaccagaaa
    11521 cagcaccagt gaatgctgca actttttcta cccattctgg atcgtcaggg tcaacttctg
    11581 tgatggttgt agcgattggt tttccacaat ccaagtcttc tgattcgatt ggttttggtt
    11641 ttttcaattt cgaaacgact cctacgtatt taacaaagtt atctaagcaa gtttcaagga
    11701 atttaacagt gccttcgttg gtgatatttc cgttgttatc aaaagcttcc ttagctttac
    11761 caagaaggaa ttcgttacct ggaagcgtgt aggcattaac acctggagca tcaaggattt
    11821 tacgaaggtg aacttgagca cgtgatgttc cttggtcata gtatgatgca cccacaatca
    11881 taacaggctt gttttcaaat ggatgaactt cgtatgaaag ccattcaagt acagatttga
    11941 gtgaagctga gatagtgtgg ttatgctcag gagtagcaat gataacacca tctgcacgag
    12001 taattttgtt atataaataa cgtaattgga aactttcatc ccatttttca tcttggttaa
    12061 acattggaac ttcgtcaatt tcaagaactt ctaattcaaa tttgagtttg aagtagcgac
    12121 ggataaattc caagagctta cggttatatg attgatcgta gtttgatcca acaagtccaa
    12181 caaatttcat tctttttggt ctcctatctt acaaattttc ccagtcaaag tcttcagcat
    12241 ctttgcgaag taattcttgt gcattacgta atttttctgt gatttttaca aagatacgga
    12301 agtcatcaaa gatggcatcc aatttcttga taacatcaag gtcaaccaag tcgccacttg
    12361 ggttaaatgc ttgaagagag tgtgagagca agaattcatc tggaagaaca tttgccttga
    12421 tttcaggagc attcaagatt tgacgaagtt gcaattgggc acgagatgaa ccaagcgtac
    12481 cgtaagaagc acctgtaatc atgattggtt tgttcaaaag tgggtaaata ccataagata
    12541 accaagcaag agcgctcatc aaaacagctg gaatagagtg atcatactca ggagtaccga
    12601 taataacgcc atctgcctct tcgattttag cagcaatttc caatatttca gcaggtactt
    12661 gcttgtcagc tggtttgttg aagacaggaa tggccttgat ttcaacaagt tcaatttcag
    12721 ctttgtcagt aaagtgtttt tgcatgtatt gaagcaattg acggtttgta gaacgttttg
    12781 aatttgttcc aacaatagca ataagtttta acatgagatt tcctttctct ttttacataa
    12841 tacaatttta aaattccatt gaaacagttg tctctataga gtaggaattc ctgaagaaca
    12901 gcttaggtgg ccttctttat cgatgaggat gacttcgatg ccctccaaac tttcgacttg
    12961 ccagaggata gaagcaggtc tttctccaaa gagtcgagtc gtccagattt cgccatcgac
    13021 tgatttatca gagatgattg ttagactcgc tagttccgtt tcaacaggat atcctgtttg
    13081 actgtcaaaa atgtgatggt aatcttgtcc atcgacggtc aggtgacgtt cataaatgcc
    13141 tgaagtcacg acagatttat tgacaacagg gatggtcatt aaatgatttc ccctaggatt
    13201 ggctgggtct tgaatcccga tttgccatgg gttatcccct cttgcctgat tttttccaat
    13261 ggtcaggata ttccctccca gattgatcaa ggcagaagtc accccctctt tcctaagaaa
    13321 ttgggcaacc ttatccgcac tgtatccttt ggctaaacaa cctagatcga tcttcattcc
    13381 tttctgtttt aaaaacacag tagaagtaga agaatctaac tcgataccat gaggattgat
    13441 tagaggcagc accgattcaa tttcttgagg ctgggcgacc ttggcatctg aaaaaccgat
    13501 acgccaggtt tgaattaagg gaccaatgct gatattgagg tggctagaga gcgctaggct
    13561 atgctctaac ccaagtgaaa tcagctcaaa caggtctgga tgaaccgtga cgggggctat
    13621 tcctgcttga taattgattt ccatcaactc agattcttga ctattggcgt tgaagcggta
    13681 ttcaagttct ttgagcaagt caaaggattt ttggagaaag atatcggctt gctcatccac
    13741 taatgaaata gtgatagtag tccccattag ccgttcagaa tgtgaacgaa gagtcaagct
    13801 accaactcct ttctcttata gaaaataagt tgtaatatca aataatcatc taaattgaag
    13861 cccttacatt tcattttcat gttattataa taccataaag ttagaatttt cacaaacaaa
    13921 atttggaaaa agtcaagaaa tatgctcata aaattcatca ggcttgaaaa caggataaat
    13981 ggggaattat ttttgataaa aaatgctgaa ataatagtac cccccttgta aacgctaacg
    14041 gtaaatggta tactagtaag gtaaatttag aatgaaggca ggaaattttt atgagtaaaa
    14101 tcgttgtagt cggtgctaac cacgctggta cagcatgtat caataccatg ttggataatt
    14161 ttggaaatga gaacgaaatt gttgtatttg accaaaactc taacatctct ttcctaggat
    14221 gtggaatggc tctttggatt ggtgaacaaa ttgacggtgc tgaaggcttg ttctattctg
    14281 ataaagaaaa attggaagct aaaggtgcta aagtttacat gaactcacct gttctttcaa
    14341 tcgactatga taacaaagta gttacagcgg aagttgaagg aaaagagcac aaagaatcat
    14401 acgaaaaatt gattttcgct acaggttcta caccaatctt gccaccaatc gaaggtgttg
    14461 aaattgttaa aggaaaccgc gaatttaaag caactcttga aaacgtacaa ttcgtgaaat
    14521 tgtaccaaaa tgctgaagaa gttatcaata aactttctga caagagccaa cacctcgacc
    14581 gtatcgccgt tgttggtggt ggttacatcg gtgttgaact tgctgaagcc tttgaacgtc
    14641 ttggaaaaga agttgtcctt gttgatatcg ttgatactgt cttgaacggt tactatgaca
    14701 aagacttcac acaaatgatg gcgaagaact tggaagatca caacatccgc ttggctctag
    14761 gtcaaactgt taaagcaatc gaaggtgacg gtaaagttga acgcttgatt actgacaaag
    14821 aaagctttga cgtggatatg gttatccttg cagttggttt ccgtccaaac acagcccttg
    14881 caggtggtaa gatcgaactc ttccgcaacg gtgccttcct tgtagacaag aaacaagaaa
    14941 catctatccc agacgtttac gctgttggtg actgtgcgac tgtttatgac aatgctcgta
    15001 aagatacaag ctatatcgct cttgcttcaa atgctgttcg cactggtatc gttggtgcct
    15061 acaatgcttg tggacatgaa ttggaaggaa tcggtgttca aggttcaaat ggtatctcaa
    15121 tctacggtct tcacatggtt tcaactggtt tgactcttga aaaagcgaaa gctgctggtt
    15181 acaacgcaac tgaaacaggc tttaacgatc ttcaaaaacc agaattcatg aaacatgaca
    15241 accatgaagt agcaattaag attgtctttg acaaagatag ccgtgaaatt cttggtgccc
    15301 aaatggtttc ccatgatatt gcaattagca tgggaatcca catgttctca cttgctatcc
    15361 aagagcatgt gacaattgat aaattggcat tgacagacct cttcttcttg ccacacttca
    15421 acaaaccata caactacatc acaatggctg cccttacggc tgaaaaataa aaatgaatga
    15481 gctatctggc cttaagttaa ggtcagatag tttttagcta atctgtcccc atacaattat
    15541 agttttttta tcttgtgctt cattctgttc tgacttaaaa tgaaaaggta gctaccaata
    15601 caaatgatga ggataaaaca aatgactgaa aatcgttatg aactaaataa aaacttggca
    15661 cagatgctca agggtggtgt tattatggat gtgcagaatc ctgaacaggc tcgtatcgca
    15721 gaagctgctg gtgcggcagc tgtgatggcc ttggaacgaa ttccggctga tattcgtgca
    15781 gctggaggag tttcccgcat gagcgaccca aagatgatta aggaaatcca agaagcggtt
    15841 agtattccag taatggctaa ggtcagaatc gggcattttg ttgaagctca gattttagag
    15901 gctattgaaa ttgattatat cgacgagagt gaagttctat ctccagctga tgaccgtttc
    15961 catgtggaca agaaagaatt ccaagttcct tttgtctgtg gtgctaagga tttgggtgaa
    16021 gccttgcgtc gtatcgctga aggtgcttcc atgattcgta ccaaaggaga accagggaca
    16081 ggggatatcg tccaagctgt tcgtcatatg cgtatgatga atcaggaaat tcgccgcatt
    16141 caaaacttac gtgaggacga gctttatgtt gctgccaagg atttgcaagt ccctgtagaa
    16201 ttggtccaat atgttcatga acatggaaaa ttgccagttg taaatttcgc tgctggaggt
    16261 gttgcaacgc cagcagatgc tgcgttaatg atgcaactag gggcagaggg ggtctttgtc
    16321 ggttcaggta ttttcaagtc aggagatcct gttaaacgag cgagtgccat tgttaaggct
    16381 gtgactaact tccgtaatcc tcaaatccta gctcaaatct ctgaagattt aggagaagcc
    16441 atggttggta ttaatgaaaa tgaaatccaa attctcatgg ctgaacgagg aaaatagatg
    16501 aaaatcggaa tattggcctt gcaaggggcc tttgcagaac atgcaaaagt gctagatcaa
    16561 ttaggtgtcg agagtgtaga actcagaaat ctagatgatt ttcagcaaga tcagagtgac
    16621 ttgtcgggtt tgattttgcc tggtggtgag tctacaacca tgggcaagct cttacgtgac
    16681 cagaacatgc tacttcccat ccgagaagcc attctatctg gcttaccagt gtttgggacc
    16741 tgtgcgggct taattttgct ggctaaggaa atcacttctc agaaagagag tcatctagga
    16801 actatggata tggtggtcga gcgtaatgct tatgggcgcc aattaggaag tttctacacg
    16861 gaagcagaat gtaagggagt tggcaagatt ccaatgacct ttatccgtgg tccaattatc
    16921 agcagtgttg gagaagatgt agaaattcta gcaacagttg ataatcaaat cgttgcagcc
    16981 caagaaaaaa atatgttggt aacttctttt catccagaat tgacagatga tgctcactta
    17041 caccagtact ttatcgaaat gtgtaaagaa aaaagacagt aaaaaagctc aaaaaatcac
    17101 ttcctgtgct atactgtaat tgaaattttt ttagtttttg cgttagaact gtttcctcag
    17161 tcctagcgcc ttttcttttt gataagtctg cttggtggag agtagtttgt aaacgattct
    17221 gagaatctta tgagcacaag caatgacggc tttcatcttg cttcctcttt gggaaattcg
    17281 attgtaaaac tctaagcagg cagagcctgc ttagagtttt acatatgcta ctatctttgt
    17341 tatagctaac ttaaattctc atttattaag tatacctaag ttttatgttt aaattttgta
    17401 tagaatagtt gtatcactta acaaagctat gtttacgctt tcaatcaagt ctcatttatg
    17461 atactattat ggtaatagaa aaaattctta gttcgctaaa gacctttatt cgagatccag
    17521 aggaaataga aattttatcc attaaa
//
LOCUS       DAVKEV010000044        17071 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVKEV010000044 DAVKEV010000000
VERSION     DAVKEV010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17071
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.044"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            366..1412
                     /gene="pheS"
                     /locus_tag="VWZ68_001681"
     CDS             366..1412
                     /gene="pheS"
                     /locus_tag="VWZ68_001681"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEU9372678.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1412..1921
                     /locus_tag="VWZ68_001682"
     CDS             1412..1921
                     /locus_tag="VWZ68_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9372679.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1998..4403
                     /locus_tag="VWZ68_001683"
     CDS             1998..4403
                     /locus_tag="VWZ68_001683"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEU9372680.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNESAADALSVSIGTDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(4471..5472)
                     /locus_tag="VWZ68_001684"
     CDS             complement(4471..5472)
                     /locus_tag="VWZ68_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU9372681.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTDSGIAPVTVIVKKSYDFYTKAETFHTTRFGTIVLHSRKQDIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5628..6117
                     /locus_tag="VWZ68_001685"
                     /pseudo
     CDS             5628..6117
                     /locus_tag="VWZ68_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6201..6467
                     /locus_tag="VWZ68_001686"
     CDS             6201..6467
                     /locus_tag="VWZ68_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9372682.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            6728..8977
                     /gene="metE"
                     /locus_tag="VWZ68_001687"
     CDS             6728..8977
                     /gene="metE"
                     /locus_tag="VWZ68_001687"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEU9372683.1"
                     /translation="MSTTIVGFPRLGEFRELKFTTEKYFRKEISEEELLSAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFTTERVGENAELRARIAG
                     LTDADYTRLPVFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            9041..9907
                     /gene="metF"
                     /locus_tag="VWZ68_001688"
     CDS             9041..9907
                     /gene="metF"
                     /locus_tag="VWZ68_001688"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEU9372684.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELVPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKERAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10592..12805
                     /gene="pnp"
                     /locus_tag="VWZ68_001689"
     CDS             10592..12805
                     /gene="pnp"
                     /locus_tag="VWZ68_001689"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEU9372685.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMTGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            12821..13438
                     /gene="cysE"
                     /locus_tag="VWZ68_001690"
     CDS             12821..13438
                     /gene="cysE"
                     /locus_tag="VWZ68_001690"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEU9372686.1"
                     /translation="MGWWHETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13450..14334
                     /locus_tag="VWZ68_001691"
     CDS             13450..14334
                     /locus_tag="VWZ68_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9372687.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14421..15764
                     /locus_tag="VWZ68_001692"
     CDS             14421..15764
                     /locus_tag="VWZ68_001692"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEU9372688.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15757..16143
                     /locus_tag="VWZ68_001693"
     CDS             15757..16143
                     /locus_tag="VWZ68_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEU9372689.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16147..17031
                     /locus_tag="VWZ68_001694"
     CDS             16147..17031
                     /locus_tag="VWZ68_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEU9372690.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
BASE COUNT         5066 a         3340 c         3899 g         4766 t
ORIGIN      
        1 tagaaattaa ttttactttc ccaatcgatt tgttctcatc ttatttcaat ccgctataaa
       61 gttagataag aataagctaa caagcagaag taagataggt cttgcaagaa tggtaaaaat
      121 ctgataaact aagtagtaat tgaataggaa tctgaaagac tagtagccca agggaagtat
      181 atcagggagg agagccgtga ctgcaagctc tctatatgaa agctgggtga attcacttgc
      241 gcatggattt agaaatgaag gtctgacttg tcagatgaaa acggatggta ccgcgtgtca
      301 acgctccgag tggagttttt ggcatgtggt tttcttttta tctacgagag actgatggag
      361 gaaatatgtc aactattgaa gaacaattaa aagcgcttcg cgaagaaacg ctggctagct
      421 tgaagcagat tactgctgga aatgaaaaag agatgcaaga tttgcgtgtc tctgtccttg
      481 gtaaaaaggg ttcgctcact gaaatcctca aagggatgaa agatgtttct gctgagatgc
      541 gtccaatcat cgggaaacac gtcaatgaag ctcgtgatgt cttgactgct gcttttgaag
      601 aaacagctaa gctcttggaa gaaaagaaag tcgcggctca actggctagc gagagtatcg
      661 atgtgacgct tccaggtcgt ccagttgcga ctggtcaccg tcacgttttg acacaaacca
      721 gtgaagaaat cgaagatatc ttcatcggta tgggttatca agtcgtggat ggttttgaag
      781 tggagcaaga ctactataac tttgaacgta tgaaccttcc aaaagaccac ccagctcgtg
      841 atatgcagga tactttctat atcactgaag aaatcttgct ccgtacccac acgtctccag
      901 ttcaggcgcg tgctatggat gcccatgatt tttctaaagg tcctttgaag atgatctcgc
      961 cagggcgtgt cttccgtcgc gatacggacg atgcgaccca cagtcaccaa ttccaccaaa
     1021 tcgaaggctt ggtagttggg aaaaatatct ctatggctga tcttcaagga acgcttcagt
     1081 tgattgtcca aaaaatgttt ggtgaagagc gtcaaattcg tttgcgtcca tcttacttcc
     1141 cattcacaga gccatctgtt gaggtggatg tttcttgctt caagtgtggt ggagaaggct
     1201 gtaatgtatg taagaaaaca ggttggatcg aaattatggg ggccggtatg gttcacccac
     1261 gtgtccttga aatgagtggt atcgatgcga ctgtatactc tggctttgcc tttggtcttg
     1321 gacaagagcg tgtagctatg ctccgttatg gaatcaacga tatccgtgga ttctaccaag
     1381 gagatgtccg cttctcagaa cagtttaaat aatgattaga aaagtagaaa tggcagatgt
     1441 tgaggtgttg gctaaaattg ccaaacaagc ctttcgtgaa acctttgcgt atgataatac
     1501 ggaagagcag ttacaggaat actttgaaga ggcttatagt ctgaaaactt tgtcaactga
     1561 gttgggaaat cctgactctg aaacctattt cattatgcat gaggaggaga tagctggttt
     1621 tctcaaagtc aactggggaa gtgctcaaac tgagagagaa ttagaggacg cttttgaaat
     1681 tcaacgcctc tatgtgctac aaaaattcca aggatttgga ctaggtaagc aactgtttga
     1741 attcgcactt gaacttgcta caaaaaatag tttttcttgg gcttggttag gtgtttggga
     1801 gcataataca aaagctcaag cgttttataa tcgatatggt tttgaaaaat ttagccaaca
     1861 tcattttatg gttggtcaaa aagtagatac ggattggtta ctgagaaaga aattaaggta
     1921 agaagaggat tcttctattg aaatgatagg aaaggaaaag aactagagtg acaactgtca
     1981 ttctggagaa ctaaattatg cttgtatctt ataaatggtt aaaagaattg gtggacattg
     2041 atgtgccatc acaagagttg gctgaaaaaa tgtcaactac aggaatcgag gtagagggtg
     2101 tcgaatcacc agctgctggt ctctcaaaaa ttgtcgtcgg tgaggtcttg tcttgcgaag
     2161 atgtgccaga gactcacctc catgtttgtc aggttaacgt tggcgaagaa gaagagcgtc
     2221 agatcgtttg tggtgcccca aatgtgcgtg ctgggatcaa ggtcatggtg gctcttccag
     2281 gagctcgtat cgctgataac tacaaaatca aaaaaggaaa aatccgtggt ttggagtcac
     2341 ttggaatgat ctgttcactt ggtgaattgg gaatttctga ctcagttgtg cctaaggaat
     2401 tcgcagatgg catccaaatc ttgccagaaa atgccgtgcc aggtgaggaa gtcttttctt
     2461 acctagactt ggatgatgaa atcatcgaac tttccatcac accaaaccgt gcagatgccc
     2521 tttctatgtg tggagtggct cacgaagtgg cagccatcta tgacaaggca gtcaacttta
     2581 aagaatttac tctaacagaa actaatgaat ctgcggcaga tgccctttct gtcagcattg
     2641 ggacagacaa ggcgccttac tatgcagctc gtatcttgga caatgtgact atcgcaccaa
     2701 gtccacaatg gttgcaaaac cttctcatga acgaaggcat ccgtcccatc aataacgttg
     2761 tagacgtgac aaactacatc ctgctctact ttggtcaacc tatgcatgct tttgacttgg
     2821 acacatttga agggactgac atccgtgtgc gtgaagcgcg tgctggtgaa aagttggtga
     2881 ccttggacgg tgaagaacga gacttggctg agacagacct cgtgattaca gttgctgaca
     2941 aaccagtagc ccttgccggt gttatgggtg gtcaggctac agaaatttct gaaaaatcta
     3001 gtcgtgttat ccttgaagct gctgttttta atggcaaatc tatccgtaag acaagtggtc
     3061 gcctgaacct tcgttctgag tcatcttctc gctttgaaaa aggaattaat gtggcaacag
     3121 ttaatgaagc ccttgatgcg gcagctagcc tgattgcgga acttgcaggt gcgacggtgc
     3181 gtaagggtat cgtttcagcg ggtgagcttg atacttcaga tgtagaagtt tcttcaactc
     3241 ttgctgatgt taaccgtgtc ctcggaactg agctgtctta tgctgatgtc gaagacgtct
     3301 tccgtcgtct tggctttggt ctttctggaa atgcagacag ctttacagtc agcgtaccac
     3361 gtcgtcgttg ggatatcaca atcgaagctg atctctttga agaaatcgct cgtatctatg
     3421 gatatgaccg tttgccaacc agccttccaa aagacgatgg tacagctggt gaattgactg
     3481 tgacacaaaa actccgccgt caagttcgta ccattgctga aggagcaggt ttgacagaaa
     3541 tcatcaccta tactctaaca actcctgaaa aagcagttga gtttacggct caaccaagta
     3601 accttacgga actcatgtgg ccaatgactg tggatcgttc agtcctccgt caaaatatga
     3661 tttcaggtat ccttgatacc gttgcctaca acgtggctcg taagaataaa aacttggccc
     3721 tttacgagat tggaaaagtc tttgaacaaa caggtaatcc aaaagaagaa cttccaaatg
     3781 aaatcaacag ttttgccttt gccttgacag gcttggttgc tgaaaaagat ttccaaacag
     3841 cagcagttcc agttgatttc ttctatgcta agggaatcct tgaagcgctc tttactcgct
     3901 tgggactaga agtgacctat acagcaacag ctgagattgc cagccttcac ccaggacgta
     3961 cagcagtcat ttcactcggt gaccaagttc ttggttttct tggccaagtg catccagtca
     4021 ctgccaaggc ttacgatatt ccagaaacgt atgtagctga gcttaacctt tcagccatcg
     4081 aaggggcgct ccaacctgct gttccatttg tggaaatcac gaaattccca gcagtcagcc
     4141 gtgacgttgc ccttctcctc aaggcagaag taactcacca agaagttgta gatgctatcc
     4201 aagctgccgg cgtgaaacgt ttgacagata tcaaactctt tgacgtcttc tcaggtgaga
     4261 aattgggact tggtatgaag tccatggctt atagcttgac cttccaaaat ccagaagata
     4321 gcttaacgga cgaagaagtc gcacgctata tggaaaaaat ccaagcatcg ctcgaagaaa
     4381 aagtgaatgc agaagtgcgt taaacgatag taggatataa attccccctc tagtttatga
     4441 acactagagg ggtgatttta tataaaataa ttaaaatgtg atttctgtaa aaatacatct
     4501 atgatcagag ttttgaaaac ttacaatgtc taaatcttta acatagtagt ggtttttagg
     4561 caataaaata tgatctatcg ttgcattaaa aagttttgga ctttggctat tccaagttcc
     4621 tctttcaaaa ggtggcagtg catttaatgc gtccctatga gagcttattt ttgcaagtgc
     4681 tccatgacgc atagttgcat taaaatcacc tgcaataata gcctttggat attttgaagc
     4741 caattgatta tgaatgatgt ttaagtcttg cttccagatt tccattaaac ctggcagagg
     4801 aggagcagta tgcaaagcaa tgatatctgg tatatcttgt tttctcgaat gtaatacaat
     4861 tgtcccgaac cgtgttgtat gaaaagtttc agcttttgta tagaaatcgt aacttttctt
     4921 gacaatcaca gtcacaggag ctattccact gtcagtaggt ggagaagtaa aaatatcata
     4981 gttggccata gaaagtccaa cttgatgaaa caatagtttg attctctggt tttcttgctc
     5041 acctctgata ttggtagcta gttcagggaa tatagccata tcggcgtcaa aatggctaaa
     5101 aattcgctca atatgttgtg cttctatttg attagcgacg ttccaagtta ctaattttaa
     5161 ggttttagtc ttatttgatg cggaagaaag ggttttatct gttccgaata atagtaatat
     5221 gagcgataat aagagcaaaa tgccagagta aaaccgtatt tgtttatttt tcttgtaaaa
     5281 agatagggaa aaaaatacga aacttaaaat ggcagccata gttgcagtag ctaaggggaa
     5341 ggcataaatc tgtgccaaga taggtctggt agatagccaa atattaagat tagaagatgg
     5401 aaaaaaagaa taagttatga tagggataac aaagagaatg accgaaaggg cagagagaaa
     5461 tgttttaatc attgtgtgag tacctcaatt tgcaatggtt gctcggagct aatgtgactt
     5521 tgtgacttta cttgattgat attctttttc ttgtcttcct tatagattaa gtacaaccca
     5581 agtaaaaaaa gtccaattta agattgaaat gattaaaagg cacagagatg caagacaatt
     5641 atactacaaa aggtaaacat ttgacaatcg atagccgtcg cttaatcgaa agatggaaaa
     5701 aagaaggaaa atcaaataga gaagttgcct ctctacttgg aaaagctcct caaactatcc
     5761 acactgaaat caagcgtggg acagtccgaa aatgtcttgg aaaagggcgc ttcaaagagg
     5821 tttattctgc cgactacgct caacagtctt atgaaaacaa tcgcaagcgc tcggtcaaga
     5881 aatcaagctt gaccaaggaa ctaaaggaaa agattctcca ctatacataa ccaaaaattt
     5941 ttgcctgaaa tgatggtgat ggctaaaggg gttaacgtgg gaatttcaac catttactat
     6001 tggattcatc atggaaagtt ggggttaagc aaacaggatt tgctttatcc tagaaaagga
     6061 aaatctgtta agaaacaagt tagtcccaat tttaaacccg ctgatcaatc tatcgaatca
     6121 taattcgctc atttttttaa aaatacatag acgtaaaaaa aagagggtta agtgatgaag
     6181 aatagtgcta ttgggagtaa ttggaaggat gtccatctga gctctttagc aaggaggaaa
     6241 tccttgaaag tgatatgcga gtggctatca tgagcgagtt gattgaggct aggtatgaac
     6301 aaggaatcag tcagaaaaag ctggaagaag tcagtggaat aagccagcct gtcatagcta
     6361 ggatggagac aggaaagact agtcctcagt tggatacagt cttaaaagtc ctagccagtt
     6421 taggaaagac actagcaatc gtcccacttg aacagggaaa aagttgacta gaatcagtta
     6481 tagtcttttc taataacaag ccatagtcac ttataagaat tactaataac gcgtttgagc
     6541 attctaacta aaatacagct ataaaacaag ctatacaaag gatttgagac gtttgcttca
     6601 agtctttttc ttttgtccga aacagatata tagtttcaaa ctatatcaaa ccctaatttt
     6661 ttacaattat acagacgctt tcttttctgt taagatagtt tcaacaacaa attttggagg
     6721 acacatcatg tcaactacaa tcgtcggttt ccctcgtttg ggcgaattcc gtgaattaaa
     6781 atttacaact gaaaaatact ttagaaaaga aatctcagag gaagaacttt tatcagcagc
     6841 aaaagacttg cgtgctaaac actggaacat tgtcaaagaa aaaggcatca ctgaaattcc
     6901 atcaaatgac ttttctcact atgataactt cctagatgcg gctttccttt tcaacgtggt
     6961 gcctgcatcc gttcaaaact tggacttgtc tgaccttgag cgctacttcg ctttgggacg
     7021 tggttaccag ggagaaaaag gggacgttcg cgcccttcca atgaagaaat ggttcaacac
     7081 taactaccac tacatcgttc ctaaatttga aaaagacact caagtaaaat tggctggtca
     7141 caagattttc gatgagttcc aagaagccaa agaacttgga ttgaacactc gtcctgttct
     7201 tgtaggtccc ttcactttcc ttcaattgtc agactttgaa gaaggcgtga aagcagacga
     7261 cttcgtagat agcttagtgg ctgcttacca agaagttttt gctaaattgg ctgaacttgg
     7321 tgcgactcgc atccaattgg atgaagcggc tcttgtaaaa gacttgacag ctgaagaaaa
     7381 agctctcttc ttgaaccttt acaacaaact cttggctgac aaaaaaggtc ttgaagtctt
     7441 gcttcaaact tatttcggtg atgttcgtga cgtatacgct gaccttgtaa acttaccagt
     7501 agatgctatc ggtcttgact ttgttgaagg taagaaaact cttgaactcg ttaaaggtgg
     7561 cttcccagct gacaagactc tctatgtagg tattgtcaat ggtaaaaaca tctggcgcaa
     7621 caactacgaa aagagcttgg ctgttcttga gcaaatccca gctgaaaaca tcgttttgac
     7681 aagctcttgc tcacttcttc atgtgccatt tacaactgct aatgaagaat ttgaaccagc
     7741 actcttgaac cactttgcct ttgcagttga aaaattggat gaaatccgtg acttggatgc
     7801 tatccgcaat ggtcaaggtt cagaagctct tgcagccaac aaagaactct ttacgactga
     7861 gcgtgttggt gaaaatgctg aacttcgtgc gcgtatcgct ggcttgacag acgcagacta
     7921 cactcgtttg ccagtctttg cagaacgtga agctatccaa gaagaagctt tcaaacttcc
     7981 agctcttcca acaacaacga ttggttcatt ccctcaaaca aaagaagttc gtgccaaacg
     8041 tttggcttac cgtaaaggtg aattgtctca aaaagagtac gatgctttcc ttgctgaaac
     8101 gattgacgaa tggatcaagt ggcaagaaga tattgacttt gatgtccttg ttcacggtga
     8161 atttgagcgt aatgacatgg ttgagtactt cggtcaaaac ttgtcaggat acctcttctc
     8221 taaaaatggt tgggtacagt catacggtat gcgtggggtg aaaccaccaa tcatctgggg
     8281 tgatgtcact cgtcttaacc ctatcactgt taaatggtct agctatgcac aaagccgtac
     8341 aaacaaacct gttaaaggta tgttgactgg acctgttacc atcctcaact ggtcattccc
     8401 acgtgaagac atctctatca aggattcaac tcttcaaatc gcccttgcta tcaaggatga
     8461 agtgcttgac cttgaagctg ctggtgtgaa aatcatccaa attgatgagg ctgctcttcg
     8521 tgaaaaattg ccactccgcc gtagcgactg gtacgaagac taccttgact gggctattcc
     8581 tgccttccgc ttggtacact caacagtagc gccagacaca caaatccaca ctcacatgtg
     8641 ttactcagaa tttacagata tcatcccagc tatcgataac atggatgcag acgttatttc
     8701 ctttgaagct agccgttcaa accttgaaat cttggacgaa ctcaaagcga aaaacttcca
     8761 aacagaagtg ggacctgggg tttacgatat ccactcacct cgtgtaccaa atgaaggcga
     8821 aatcgacaac acaatcgaag ccatccttgc taaagtgcca agcaagaaag tttggatcaa
     8881 ccctgactgt ggtttgaaaa cacgtggtat cccagaaaca aaagaaagct tgatccgcct
     8941 tgttgaagca gctaaagctg cgcgtgagaa attgtaagat tggatttctc tccatacagt
     9001 ggttgttcaa aaagaaatca actagaaaag gttattacat atgtcacgcc aaacaccgtc
     9061 actctcattt gaagtgttcc ctccaaaccc agccgtgggt aatgataaca ttatttcagc
     9121 cttgcaggat atgcaggagt tggttcccca ttttatcagt gtaactgcca gcaataataa
     9181 atttaatatc aaggaaacga cggttcgttt ggctgacttt atccaaaatg atttggcgat
     9241 tccgaccatt gcccacttgc cagctattta tctaactaag gacaaggttg ctgaaactat
     9301 tgctgacttg gacaaagttg gggtgcagaa aatcttggct cttcgtgggg atattattcc
     9361 agacgtggaa ccacaaaagg atttccgcta tgcaaccgac ttgattgagt ttatcaagga
     9421 acgagcccct cactttgata ttattggagc ttgctatcca gaagggcatc cagattcgcc
     9481 aaatcagatt tcagatattc aaaatcttaa gaagaaagtg gatgcaggct gttcgagcct
     9541 cgtaactcag ctcttctttg acaatgagcg cttctatgat tttcaggaca agtgtatctt
     9601 ggctgggatt gatgttccca ttcatgcagg aattatgcca attctgaatc gaaatcaggc
     9661 tctccgactc ttgaagactt gtgagaatat ccatcttcca cgcaaattta aagccatctt
     9721 agacaagtat gagcatgacc ctgagtcgct cagagcagca ggacttgcct atgcagtgga
     9781 ccaaatcgtg gacttggtaa ctcaggatgt tgccggtgtg catctctata cgatgaataa
     9841 tgctgataca gcaaaataca tccatcaagc aacccatgcc ttgtttaatc accagtctct
     9901 aggataataa aagcaaacca ttcttctcag gtgaggggaa tggttccttt ttaatggtaa
     9961 agacctcact ttttaagaaa aatatgataa aataaattct gtacgtactt gatacaaaga
    10021 tgaaggtatt aaataataca atgcatttaa actgtaagat ttaacgacac gagtgagtca
    10081 aatcgatgtt atttgacgag agagttagta aagcatttag ctaatcgccc gatagcgatt
    10141 agcgtgaaag ctttagatac tttagtatta aacctttcta atgatgtatc ttgaaaactg
    10201 aacttgccta caactctgtg gaaaaagata aatctcccta ggagtagtcg ctccgtcgtt
    10261 cgatttccta tcttcctttg agttgcttga cggcttggta tcttgatgac ttgaattttg
    10321 gtctcatttc ttaggaaaaa agataagctt cctagcactc gtcgagtgtg acgtcacctt
    10381 cctatttttc tacagaaatg ttcggcaagc cgaaccgtcc aaaatatctt gtgtaattga
    10441 acacggccga aaagctgtgt aaaaaagata aactgtcttg tcttcatcga agacttcgtc
    10501 agtttcctat ttttactttg cttttgacgt ccttggtatc ttgatctttg taggcaaggc
    10561 gtataatttc atcaatccaa aggggattaa aatggcaaaa caagtgtttc aaacgacttt
    10621 tgcgggtcgt gagttaattg tagaaactgg tcaggttgct aagcaagcaa atggctctgt
    10681 tgtcgtacgt tacggtgagt caactgtctt gactgctgcc gttatgtcta agaaaatggc
    10741 aactggggat ttcttcccac tccaagtcaa ctacgaagaa aaaatgtatg cggctgggaa
    10801 gtttcctggt ggctttatga aacgtgaagg acgtccttca acagatgcga ccttgacagc
    10861 gcgtttgatt gaccgtccga ttcgtcctat gtttgcggaa ggtttccgta atgaagtcca
    10921 agtcatcaat acagtgcttt cttatgatga aaatgcatct gcaccaatgg ctgctatgtt
    10981 tggttcatct ttggcactgt ctatttcaga tattccattt gacggaccaa ttgctggggt
    11041 acaagtggga tatgtagatg gccaaatcat catcaaccca agtcaagaac aagcagagca
    11101 atctcttctt gaattgacag tagctggaac caagcacgct atcaacatgg tagagtctgg
    11161 tgccaaagaa ttgtcagaag aaatcatgtt ggaagcgctt cttaaagggc acgaagctgt
    11221 caaagaattg attgccttcc aagaagaaat cgttgctgct gtcggtaaag aaaaagcaga
    11281 agtggaattg cttcacgtgg atgctgaatt gcaagctgaa atcattgcag cctacaacag
    11341 tgacctccaa aaggcagttc aagtagaaga gaaattggcc cgtgaagctg caactcaagc
    11401 agtgaaagac caagtgactg ccgtttacga agaaaaatat gcgaaccacg aagaatttga
    11461 ccgtattatg cgtgatgtgg ctgaaatctt ggaacaaatg gaacacgcag aagtgcgacg
    11521 tttaattaca gaagacaagg tgcgtcctga tggtcgtaag gtcgatgaaa tccgtccttt
    11581 ggatgcggtt gttgacttcc ttcctcgtgt acatggttca ggtctcttta ctcgtgggca
    11641 aactcaagct ctttcagtct tgaccttggc tccgatggga gaaactcaaa tcattgatgg
    11701 tttggatcca gagtacaaga aacgctttat gcaccactat aacttccctc aatattctgt
    11761 aggggaaaca ggtcgttacg gtgcgccagg tcgtcgtgaa atcggtcacg gtgcccttgg
    11821 tgagcgtgct cttgctcaag tcttgccaag cttggaagaa ttcccatacg ctatccgtct
    11881 agtagcagaa gttttggaat caaacggttc ttcatctcaa gcttctatct gtgcgggaac
    11941 tcttgccctt atgactggtg gtgtgccaat caaggcgcca gtagctggta ttgctatggg
    12001 acttatctca gatggaaata actacacagt attgacagat atccaaggtt tggaagatca
    12061 ctttggagat atggacttca aggttgcagg tactcgtgat gggattacag cccttcaaat
    12121 ggatatcaag attcaaggga ttactgcaga aatcttgacg gaggctcttg ctcaagccaa
    12181 gaaagcgcgt tttgaaatcc ttgatgtcat tgaagcaacc attccagaag ttcgtccaga
    12241 attggctcca actgctccga aaattgatac gatcaagatt gatgtggaca agattaagat
    12301 tgtcatcggt aagggtggag aaaccatcga caagattatc gctgaaacag gtgttaagat
    12361 tgatatagac gaagaaggaa atgtgtctat ctactctagt gaccaagatg ctattaaccg
    12421 tgccaaagaa attattgctg gtttggttcg tgaagccaaa gtggatgaag tttaccgtgc
    12481 taaagtcgtt cgtatcgaga aatttggtgc ctttgttaac ctctttgata agacagatgc
    12541 ccttgttcat atctctgaga tggcttggac tcgtaccaat cgtgtagagg atttggtaga
    12601 aatcggggat gaagttgatg ttaaggttat caagattgat gaaaaaggcc gtatcgatgc
    12661 ctctatgaag gctcttctac ctcgtccgcc aaaacctgag catgatgaaa aaggtgaaaa
    12721 gtctgagcgc cctcaccgcc cacgtcatca caaggatcac aaacctaaga aagaatttac
    12781 agaaacacca aaagattcag agtaagaaaa ggagaaatgt atggggtggt ggcacgaaac
    12841 cattgatatc gtaaaagaaa atgatccagc ggcccgcacc actttggagg ttttgctgac
    12901 ttatccaggt gtcaaggcct tggcggccca ccgtctctcg cattttctct ggaagtacga
    12961 cttcaaactc ttagctcgta tgcacagtca gttttggcgc ttttggactc agattgagat
    13021 tcatccagga gcccagattg attcaggtgt ctttattgac catggttctg gtctggtgat
    13081 tggagagaca gcgattgttg aaaaaggcgt tcttctctat cacggagtga ctctcggggg
    13141 aacagggaaa gactgtggca aacgccatcc gactgtacga aagggagccc tcatatcagc
    13201 ccatgcccaa gttatcgggc ctgtggaaat tggtgaaaat gccaaggtcg gtgctgcagc
    13261 agttgtcgta gcagatgtac ctagtgatgt gacggttgtc ggtattccgg ccaagattgt
    13321 ccgtcttcat ggtaagaaag atgagcctgt tattcacgaa gtcgaagaaa aacgggagta
    13381 ttatgtcaat aaactcgagc aggctaaaga tgccagtcac agatcgtctg gtttgtagag
    13441 gatacctata tgattcaagc aagaaacaag ttaagccaag aggagctatc tgaggcgaaa
    13501 aaagtaatta actgttgcca aaactatgac ggtacctatc gcgatcccta tctctctaac
    13561 atgcttaatt ttgacccaaa catgcccgcc tttttccttt attatgaaaa aggcaaactt
    13621 gttggtttat taactgtcta tgcagatgac caagatgtag aagtgacgat attggttcat
    13681 ccaggtcatc gccgtcaggg gattgcgcgt gcattgttta ctagttttga gagagaaaca
    13741 gcttctttcc ccattcggtc agtcactttt cagacagaac gtattttttt agagaatcat
    13801 cctgactttg ccagtaactg gggactaatc gaggatgaag agacagaaac ttggttaggt
    13861 aaggatagaa gaccttatcc gttagcaaat gtttcccatc ttgaagtttt gttagcagat
    13921 agttcgtatc aggatcaaat tagtcaatta aaatttcagg cattttcaga ggaacatgaa
    13981 tcgagagaag ttgtggatag atatgtcgct gaagctctga aggatccaga aagtcgctta
    14041 tatattttgt taaaagacgg tcaggttatt gggacttgca cggtagattt atcgactaat
    14101 acgaattact tctacggttt agcaatatcg gaacctgaac gtgggaaagg ctatggaagc
    14161 tacttagcaa aatccctcgt caaccaacta attgagcaaa atgacaagga atttcagatt
    14221 gcagtggaag atagcaatgt aggtgccaaa cgtttgtatg aaaaaattgg ctttgtcaaa
    14281 cagacacagg tggtttatct gaatgagaaa ggagcaaggg attccgaagt gtagagacat
    14341 tcggactgaa atttacttga gctcttagtt tagtgatgaa actaacagtt cttggatttt
    14401 agctttcctg attatgattt atgattaaaa tctatgacac catgtctcgt gatttgcgag
    14461 aatttgtccc gattgaggac ggcaagatca agatgtatgt ttgtgggcca accgtgtaca
    14521 actatattca cgtgggaaac gcccgttcga cggtagcttt tgatacgatt cgtcgctatt
    14581 ttgagtaccg tgggtataag gttgcctata tttccaattt tacagatgtg gatgataaga
    14641 ttatcaaccg tgccagggaa gaaggcatca cacctcagga ggttgcggat aagtacatcg
    14701 ctgcctttcg tgaggatgtg acggccttag gcgtgaaacc tgcgactcgc catccgcgtg
    14761 tagtggagtt tatggcagac atcatccgtt ttgtggaaga cttgatcgag aaaggctttg
    14821 cctatgagag tcaaggggat gtctatttcc gtgtagaaaa atcccacaac tatgctaaat
    14881 tggctaataa aaccttggaa gatttggagc taggtgcttc aggtcgtacc gatgaagaaa
    14941 cggctcgtaa ggaaaatcct gtagattttg ctctatggaa atcttccaaa ccaggtgaga
    15001 tttcttggga tagtccttgg ggacctggac gtccgggttg gcatattgag tgttcagtca
    15061 tgtcgacaga gattttaggt gataccattg atatccacgg tggtggagct gacctagagt
    15121 ttccacacca caccaatgaa attgcccaat ctgaagctaa aacaggcaag gcttttgcta
    15181 actactggat gcacaatggc tttgtcaata tcgacaatgt caaaatgtct aagtccttgg
    15241 gtaacttcat tacggtacac gatgccctta aaactcttga tgggcaagta cttcgtttct
    15301 tctttgcgac ccagcactac cgtaagccta tcaacttcac ggaaaaggca gttcgcgatg
    15361 ccgagaccaa tctcaagtat ctgaagaata cttacgaaca accatttaca ggaaacgtgg
    15421 atgcccaaga gttacaaaac tttaaagata agtttgtagc agctatggat gaagatttta
    15481 atgctgccaa cggtatcaca gttgtctttg aaatggccaa atggatcaac tcagggaact
    15541 atgatgcaag tgtcaagcaa gctcttgcag atatgttaga aatttttgga attgtctttg
    15601 ttgaggaagt tttggatgca gagattgaag acttgattca aaaacgccaa gaggcgcgtg
    15661 ccaatcgaga ctttgagaca gcagaccaaa tccgtgacca attggttact caaggaatta
    15721 agctccttga taccaaggat ggagtgaggt ggacacgtga ttgatgtcaa tctcattaac
    15781 gggattgcgc tagcctttga gggggatgcg gtgtattcta tgtatattcg ccgtcacctc
    15841 atcctcaaag gtatgaccaa acccaataaa ctccatcaag aagcaaccaa gtatgtgtca
    15901 gccaaggctc aggctcgcct gattgctctc atgttggagg agcaggtcct aacggaaaaa
    15961 gaagaagaaa tctacaaacg tggccgcaat accaatagcc acacaaaggc taaaaatgca
    16021 gatgtcgtga cttatcgtat gtccacggga tttgaagcgg ttatgggcta tctccatatg
    16081 actgagaatc tggaacgtct tgagagtttg gtttcatggt gcatccaaaa agtggagggc
    16141 tagaacatga gggaaaaaga actacaagac tggtttcctg aggctcggat ttcagaccaa
    16201 ccagtagaga aagagggcta tctcacgctc cctttagctt ctcagcagtg gattttgctg
    16261 gaggaagctg ggctcagcga gcgtgaaaag cagttggttg cccttttgac ccagcaggag
    16321 caggctcgtt cgctaaaccc ttggtattcc tatctggttg aaggcaaggg acaggcaccg
    16381 caagttttta aaaagattca gttggtttat tgccatcttt cttattttca gcaggaaaat
    16441 ctggcttctt ggctagatat gatgcggact ctttttccga attgtcagac agtgctacag
    16501 gtcggagctc aggattatgt tttcgtgctt caacaagaca aatacacttc tgtaagagat
    16561 attttaagtg atacgattga agcggttgag tatgactttg gacttcgtct ttctatcatg
    16621 ttgggtcagg tttggtctca gacaggacat caagccctat cagacttaat caaagctgag
    16681 cgggatttgt tcaagacatg gtggcgtcag ggtcaccaag gtgttcatac tttttctcag
    16741 ctctatcttt ggagtatggg agaaagactc gtggacttga agccaattaa agaatgtcta
    16801 caccagatga ttttggatca agatcagatt caggaaatca ttctctctct ttgggaaaat
    16861 agtgctgttc tcactaaaac agcccagcaa ctctatctgc accgcaattc tctccaatac
    16921 aagattgata aatgggaaga gttgacaggg cttcagttga aagagttgac cgacctgacc
    16981 ttgtgttatc aattgatttt aggttctttg tcaactatag ttggtttgta aagaagttaa
    17041 tatttggaga agaggattgc catcttctcc a
//
LOCUS       DAVKEV010000045        16729 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVKEV010000045 DAVKEV010000000
VERSION     DAVKEV010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16729
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.045"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            45..1682
                     /locus_tag="VWZ68_001695"
     CDS             45..1682
                     /locus_tag="VWZ68_001695"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU9372691.1"
                     /translation="MSIFIGGAWPYANGSLHIGHAAALLPGDILARYYRQKGEEVLYV
                     SGSDCNGTPISIRAKKENKSVKEIADFYHKEFKETFEKLGFTYDLYSRTDSPLHHEIV
                     QELFLQLYEKKFLYTKKIKQLYCTFDNQFLPDRFVEGKCPNCGTHSRGDQCDNCSAIL
                     DPIDLVDKRCSICSNEPEVRETEHFYYVFSEFQNLLETYLNDAEETVRWRKNAINLTK
                     RYLREGLPDRAVTRDLPNGIPVPIDGFRDKKIYVWFEAVAGYYTASVDWAQKLQNNIT
                     DFWNNRTKSYYVHGKDNIPFHTIIWPAILSGLEIEPLPEYIISSEYLTLENKKISTSN
                     NWAIWLNDIIKKYDADSIRYFLTINAPEMKDANFSWREFIYSHNSELLGSYGNFINRT
                     LKFIEKYFESEIPTKYLEGEILYNLKELYTTVGNLVESGHMKQALEEIFEYIRSANKF
                     YDDMKPWALRESDIEKCKEVLATCVIIILNLGQMLNPFIPFSGKKIEDMFKTKLNTWN
                     YISNLPNKLSDVSMLFDRIDLKKIDEEVLELQQTSSR"
     gene            1783..2550
                     /locus_tag="VWZ68_001696"
     CDS             1783..2550
                     /locus_tag="VWZ68_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HEU9372692.1"
                     /translation="MNNLTLLKEYNFRDLGNHLTQTGQKIKPKTLFRSSKLFGISKID
                     VDLLQSYGITKVIDFRSANEIKKAPDPDIKNIKNIVIPIFYNDDSELTEFPIEFFNKS
                     DAGFQHMIKTYDQMINQKQSKLGYKKFFKLLLSHPKDESLLFHCSMGKDRTGIASLFL
                     LYILGVDMNDIFHDYLLSNKYLINVRKENIEYVNNHSGNVILMHNLLSLSSAKEEYIN
                     RVLNVLDKEYGGILRYINTELGISSQEIEELKDRYLF"
     gene            3567..4559
                     /locus_tag="VWZ68_001697"
                     /pseudo
     CDS             3567..4559
                     /locus_tag="VWZ68_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            4561..5378
                     /locus_tag="VWZ68_001698"
                     /pseudo
     CDS             4561..5378
                     /locus_tag="VWZ68_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
     gene            5380..6165
                     /locus_tag="VWZ68_001699"
     CDS             5380..6165
                     /locus_tag="VWZ68_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9372693.1"
                     /translation="MKKYQRMHLIFIRQYLKQIMEYKADFLVGVVGVFLTQGLNMLFL
                     NILFQHIPLLDGWSFHQVAFIYGFSLIPKGIDHLFFDNLWALGQHLIRKGEFDKYLTR
                     PISPLFHILVETFQIDALGELLVGVLLLLMTITSLTWTWAKVFLFLISIPFATLIYTS
                     LKIVTASIAFWTKQSGAIIYIFYMFNDFAKYPIAIYHSFLRWLISFIIPFAFTAYYPA
                     SYFLKDKDGLFNIGGLILISLIFFTLSLKLWNKGLDAYESAGS"
     gene            complement(6544..7739)
                     /locus_tag="VWZ68_001700"
                     /pseudo
     CDS             complement(6544..7739)
                     /locus_tag="VWZ68_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713014.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            8241..8444
                     /locus_tag="VWZ68_001701"
     CDS             8241..8444
                     /locus_tag="VWZ68_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9372694.1"
                     /translation="MYIRLKNLREDKDLSQCQIAQYLHCSQSAYSRIESGKQDIPTSF
                     LKQLAKLYQVTTDYILEMDKFSC"
     gene            8575..8727
                     /locus_tag="VWZ68_001702"
     CDS             8575..8727
                     /locus_tag="VWZ68_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372695.1"
                     /translation="MTTNKDNDTSERSGCQRKRTAGEMPMNDLTSHTHGGNYTCYKEE
                     KVWNNQ"
     gene            8894..10687
                     /locus_tag="VWZ68_001703"
     CDS             8894..10687
                     /locus_tag="VWZ68_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU9372696.1"
                     /translation="MKKNNVEIIKADSLVRRRGDNVERHLKRVAAYCRVSSDSEDQKN
                     SYDSQVRHYKEYISQRSDWELADIYADEGISGTQVGKRQDFQRLINDCANGEIDYIVT
                     KAIARFARNTLDTLKYVRMLKDMQIGVYFEEENIDTLTMDGELLLTILSSVAQQEVEN
                     TSAHVKKGLKMKMQRGELVGFQGCLGYDYDVETKQISINKKEAKIVRYIFERYLEGIG
                     GKVIARELDELGYKSPRGLEHWNDTTVLGIIKNEKYKGDILMGKTFTVDPISKRRLSN
                     FGEEDKYYIKDNHEPIISKEDFEKAQEIRLRRAGNKKTAANVNGKRERYSKMYAFSSM
                     LECGFCGSILSRRSWHCRSDYRKVVWHCVTSIKKGKKFCKHSKGLEEIAIEGAFLEAY
                     RQVYHSNENLMTDLLETIESELNDNSLNKELKRITNKLRILLKKEENLVNLRLEGKVS
                     DSIYNEKYNEISSEKEFLAEEKVNIETTLKSEIDVKKRLTEFKHLLSSQKMLTEFDRA
                     VFESIVEKIIVGGVNSNGEIDPAMLTIIFKTGEIQNKDGKQFKSKRKNAKLETDKLCP
                     QNSDEDKKLYSQGTDNTRGVCSVAGSILASQ"
     gene            10792..11379
                     /locus_tag="VWZ68_001704"
     CDS             10792..11379
                     /locus_tag="VWZ68_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEU9372697.1"
                     /translation="MGGNPPIKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYINQEFKSYIDHM
                     LNKEAKIIGFSAGPLLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELDNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            11661..11909
                     /locus_tag="VWZ68_001705"
     CDS             11661..11909
                     /locus_tag="VWZ68_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
                     /protein_id="HEU9372698.1"
                     /translation="MCKPISIELCDDEVHSLHEWIDGRDAIDSILTYSENQQYTYGVE
                     AGKILRKIHTIPATEVCEDWEIFFNLKIDDKISNEMIW"
     gene            12085..12338
                     /locus_tag="VWZ68_001706"
                     /pseudo
     CDS             12085..12338
                     /locus_tag="VWZ68_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            12466..13695
                     /locus_tag="VWZ68_001707"
     CDS             12466..13695
                     /locus_tag="VWZ68_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU9372699.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGITIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLMMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            13715..16411
                     /gene="ppc"
                     /locus_tag="VWZ68_001708"
     CDS             13715..16411
                     /gene="ppc"
                     /locus_tag="VWZ68_001708"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEU9372700.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    16494..16711
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         5528 a         2527 c         3276 g         5398 t
ORIGIN      
        1 aataatgtta taataaaaat aaagaattta aggagaaata caatatgtca atttttattg
       61 gaggagcatg gccatatgca aacggttcgt tacatattgg tcacgcggca gcgcttttac
      121 cgggggatat tcttgcaaga tactatcgtc agaagggaga ggaagtttta tatgtttctg
      181 gaagtgattg taatggaacc cctatttcta tcagagctaa aaaagaaaat aagtctgtga
      241 aagaaattgc tgatttttat cataaggaat ttaaagaaac ttttgaaaaa ttaggtttta
      301 catatgactt gtactcgcga acagattctc cactacatca tgagatagta caagaattat
      361 ttttgcaatt atacgagaag aaatttttgt atacaaaaaa aattaaacaa ctctattgta
      421 catttgataa tcaattctta cctgataggt tcgttgaagg aaaatgcccg aattgtggaa
      481 cccattcaag aggagatcaa tgtgataatt gctcagcaat tttagatcct atagatttag
      541 ttgataaaag atgttctatt tgttccaatg aaccagaagt tcgtgagaca gaacactttt
      601 attatgtttt tagtgagttt caaaatttgt tagagactta cttaaatgat gctgaagaaa
      661 cagtgagatg gcgaaaaaat gcaataaatc taactaaaag gtatttacgg gaaggtttac
      721 ctgatcgagc tgttactcgt gatctaccaa atgggattcc agttcccatt gatggtttta
      781 gagataaaaa aatatatgtc tggtttgaag cggtagcagg ttactacaca gcaagtgttg
      841 attgggcgca aaaacttcaa aataatatta ctgatttttg gaacaatcgg acaaagtcat
      901 attatgttca tggaaaagat aacatcccat ttcatactat tatttggccg gcaatactct
      961 caggtttaga aatagagcct cttccagagt atattatttc tagtgaatat ttaacgttag
     1021 aaaacaaaaa aatatcaaca agtaataatt gggctatatg gcttaacgat atcataaaaa
     1081 aatatgatgc tgattcaatc cgatacttcc taacaataaa tgctcctgag atgaaagatg
     1141 caaatttttc ttggagagaa tttatttata gtcataactc agaattatta ggatcgtacg
     1201 gtaattttat caataggact ctaaagttta ttgaaaagta ttttgaatct gaaataccca
     1261 ctaaatatct cgaaggagaa attttatata atttgaaaga attatataca acagtaggta
     1321 atttagttga gagcgggcat atgaaacagg cattagaaga aatttttgaa tatattagat
     1381 cggctaataa attctatgat gatatgaaac cgtgggcatt gcgagagtcc gatattgaaa
     1441 aatgtaaaga agtcttagct acttgtgtaa tcattatact taatttagga caaatgttaa
     1501 atccattcat tcctttttct ggtaaaaaga ttgaggatat gtttaaaaca aagctaaata
     1561 cttggaatta tatttcaaac cttcctaaca agctatcaga tgtatcaatg ttgtttgata
     1621 ggattgattt gaaaaaaatt gacgaggaag ttttagaatt gcaacaaaca tccagtagat
     1681 aattcaaaaa tactcgaaag tagccttttt taatttaaat taacaaccgg agatgttgaa
     1741 taaaataaag atggtttttt gagcatatta tggagaaaag cattgaataa tctaacttta
     1801 ctaaaagaat ataattttag agatcttgga aaccacctca ctcaaacagg acaaaaaata
     1861 aaacctaaaa cattattccg ttcaagtaaa ctatttggaa tctctaaaat tgatgtcgat
     1921 ttgttacaga gctatggaat aacaaaagtc attgactttc gatcagcgaa tgaaataaaa
     1981 aaagctccag atccagatat aaaaaatata aaaaatatag taattccaat attctataat
     2041 gatgattcag agttgacaga attcccaata gaatttttta acaaatcaga tgcaggtttt
     2101 caacatatga taaaaactta tgatcaaatg atcaatcaaa aacagagtaa acttggttac
     2161 aagaaattct ttaaattatt actaagtcat ccaaaagatg aatctctttt gtttcattgt
     2221 tcaatgggga aggatcgaac aggaatagct agcttgttct tgctttatat attgggagta
     2281 gatatgaacg atatttttca tgattactta ctatctaaca agtatttaat aaatgtgaga
     2341 aaagaaaata ttgaatatgt aaataaccat agtgggaatg taatattgat gcataattta
     2401 ctttcactca gttcagcaaa agaagaatat attaatcgag tattgaatgt ccttgataaa
     2461 gaatatggag gaatacttag atatattaat acagaactag gaataagtag tcaagaaatt
     2521 gaggaattga aagatagata tcttttttag aatagtaagt actaaaaatg aatatataac
     2581 agtgcgaacg gcggttttgt ttttgtctaa ttctactaat ttaacataag caaaaacgga
     2641 ttgttttcta tgtaagtcct taactaaatt gatggaaagc acgttaaatt atgtgcaaaa
     2701 tgcgtacaaa atagtgttta tcaaatgtaa aatttcctac ttgtcatcaa agttcaacaa
     2761 atgtaggttg tttggttatt tgggtagatt tctggactta tcgttggttg tagagacata
     2821 atgttgcagt taaagcttag agaataatct ccgtattttt gttaggcaat ttaaaagtta
     2881 agacaaagtg agtttgtctc ttaattcaac tcaccacaaa cacatcacct ttttattata
     2941 acttccgacc aatttttttg aagagaaaaa tgaaaaaaca ccaactgtgc agggtagctg
     3001 acaaggcttc tagcttccat ttattgaaac caaatcaatc tgttatgaga taatagcagt
     3061 tgcagaagct gactactttg agaagttaaa tgaggtttat tatcaagaat acttcatgaa
     3121 tatagttata agggaggggg tagttgaaag aattgactca tctgttaaaa taaaaatgga
     3181 aataataaca tcataatagt gtgacttagt atttttcagc atcttggaag taggtaaatg
     3241 atattaaaat tatactgcat agtaaaggat agtaatgagg aatttaatat cttcctgtca
     3301 atatcttcag ttattaaagt atttttatat tgggataact tcgtttgctg aaatctatag
     3361 tttatccaat tataaattta tatgttcttc gtcataattc tttgtacttg agtaatttag
     3421 cttacttaca gataaaatac aagatggcat agttttagta gcttttttca tatggtttgt
     3481 aatgatggta aattttctta actttactgt agtatgctac aatttttgtt gatattataa
     3541 cttgagtgaa acgaaaggag tgatttataa aaatgataac agtagagcat cttcagaaaa
     3601 attttgtgaa aacaataaag gaacctggct taaagggagc ttttcgctct ttttttcatc
     3661 ccaagagaca agtctttgaa gctgttaaag atttatcatt tgaggtgccc aaaggacaaa
     3721 ttttaggctt tattggcgca aatggagcgg ggaaatcaac aactatcaag atgttgacgg
     3781 ggattttgaa accaacatca ggtttttgtc gtatcaatgg aaagattcct caagagaacc
     3841 gtcaaggcta tgttaaagat attggtgtag tttttgggca gcgaactcaa ctttggtggg
     3901 atttggcttt gtaggagact tactcggttt taaaggaaat ttatgatgtt cctgatgcgg
     3961 tctttcaaaa acgcatggat tttctaaatg aagttttaga tttgaaggaa tttattcaag
     4021 atcctgtcag aactctatct ctaggtcaac gtatgagggc ggatattgcg gcctccttat
     4081 tgcataatcc gaaagttctt ttcctagatg agcctactat tggtttagat gtttcggtca
     4141 aggataatat tcgacgtgcc attacacaga ttaatcaaga agaagagacg accatacttt
     4201 taacgaccca cgatttaggt gatattgaac agttatgtga tcgtattttt atgattgata
     4261 agggccgaga aatctttgat ggaactgtga atcaactgaa aaagactttc gggaagatga
     4321 agactctctc ttttgaacta catcctgggc aggattatat tgtctctcat tttgaaggac
     4381 tttctgatat ctatgtgacg agacaggaat tgtcacttga tattcagtac gacagctcgc
     4441 agtatcaaac ggctgacatt attcaacaaa ctttgtctga ttttacgatc cgtgatttaa
     4501 agatgacgga tgcgaatatt gaagatatta ttcgtcgctt ctatcgaaag gagctttagg
     4561 atgactaaat tatggaaacg ctataagcct tttgttagcg ctggaatcca agaattaatc
     4621 acgtatcgtg tcaatttttt tctttatcgc attggggatg tgatgggggc ctttgtagca
     4681 ttttacttgt ggaaagctgt gtttgattca tctcaccagt ctctcattca aggttttact
     4741 ttatctgata tgaccttata tatcatcatg agttttgtga cgaatctact gacaaaatca
     4801 gatagttctt ttatgattgg atgggaagta aaggatggct ctattattat gcgactgctt
     4861 cgtccagttc attttgcaat gtcttatctt ttcacagaaa ttgggtctag atggctagtt
     4921 tttgttagtg ttggtctacc atttgtaatt ctgattgcag gtctaaagct cttatcaggt
     4981 gagtccttct tacaaattgt tttaataacc acagtttacc ttcttagctt aatcttagct
     5041 tttttgatta attttttttc aatatttgct ttggtttttc agcttttgtg tttaaaaact
     5101 tatggggatc aaatcttttg aaaaattctt tagttgcctt tttatctgga agtttggttc
     5161 ctctgacatt ttttccaaaa attattgccg aactattatc ttttttgcca ttttcttctt
     5221 taatctatac cccggtgatg gttattatag aaaagtatag catgagtcaa atgattcagg
     5281 cgctctcgct acaattattc tggctgttta ttatgattgc cttatcccaa ctgatttgga
     5341 agtgcgtaca gaattatata actattcaag gaggttagaa tgaagaaata tcaacgcatg
     5401 cacctgattt ttatccgaca atatcttaaa cagattatgg agtataaggc tgatttttta
     5461 gttggtgttg tgggtgtctt tttgacacaa gggttaaata tgctgtttct aaatattttg
     5521 tttcaacata ttcccttact tgatggctgg agttttcatc aggttgcttt tatttatggt
     5581 ttttctctca ttcctaaggg aattgaccat ctcttttttg ataatctgtg ggctttagga
     5641 caacatttaa ttcgtaaagg agaatttgat aagtatttga ctagacccat tagccctttg
     5701 tttcatattt tagtagaaac gtttcaaatt gatgctcttg gagaattgtt agtaggcgtc
     5761 ttattgctgt taatgacaat aactagtctt acttggactt gggcaaaggt ttttctcttt
     5821 ttaatcagta ttccctttgc aaccttaatt tatacctctt taaaaattgt aacagctagt
     5881 attgcttttt ggactaaaca atctggggca ataatttata ttttttacat gtttaatgat
     5941 tttgcaaaat acccgattgc gatttaccat tcgtttttac gttggttgat tagttttatc
     6001 attccttttg cttttacagc ctattaccca gctagctatt tcttgaaaga caaggatgga
     6061 ttgttcaata ttggtggatt gatccttatc tcattaatat tttttacctt atcattaaaa
     6121 ttatggaaca aaggtttgga tgcatatgag agcgcagggt cttagaagaa gtaaaatcta
     6181 attaagaatt ttgatagaac ttcctattct ttggaaggaa gttttaatga tacattgaga
     6241 gctttgatta ggcttactgt agtttttcaa acaagaaatt tgaccattgt gcaaaaatga
     6301 tacaaaggta tgtaatattt cagtcataac cactcgttca tatcatgagt ggttttttag
     6361 ctcttttata cataccattt gttaagggac atacgatatt ctagctcaaa aggttttctg
     6421 aatgagtatc aaaggaatgt ttagaagata attgcgagct gttttttgaa atttgggcac
     6481 acttaaaaga cacttatctg gtattaaaaa ataaggtgtt acaatgatag gacatagatg
     6541 actttaatga ctttgggtta aagtgtagtc gtaaagtttg ttatgcgtta tgaggtaata
     6601 cattgtccgg atgaggcgat gtatagagac aatcgtatat ggcttggttg aagtcgtctg
     6661 cgattgtctt tttcgtttct cataaaagtc cgcgatatga caaggattgg tatgactagc
     6721 tgaagcaata ttgtggacgc acttatagag aatttttctc gcgtaaggat ttccacgctt
     6781 ggtgatatgt tcttgagcta ggaaattgcc agattcatag tgtctgaggt caatactgat
     6841 aaaggcattg atttggttgg cagaccgaaa gcgacgaatg tctccaattc gccaataatg
     6901 cttgtagctg ttgtttctgc gataccagga atagagagca gaatctcgta ttcaggtaat
     6961 ggttcagcca attcaatcat ttgtgctaag tcctgatcct tgcggtttgt cagtctcaac
     7021 agttcctgtg catgatactt aacctcttct gtcatgggag aggtttttga aatggcaaga
     7081 taggactgtt cggccagctc gctcaacttt tcagccaatc gtccaactct gttctcagaa
     7141 atccgtttag aagttgaatt acgatggctt cttttagctc aactactgat aatttcagcc
     7201 tccaatgctt ggttggaaag atggtcacga ggttccaata ttgttcccct gtaggagtag
     7261 agagaaggtt ctttatttct ggaaaggcaa tttgaagcac cttgtgcagg ctattcttag
     7321 tcctaacgat gtcttctgtc agattctgat agaatcgact gaggtcacgc aaattttgat
     7381 agacttcttc ttgaacataa gttggtttgc ggttaaggat gaattgtgac gaagctagct
     7441 tttcagcgtc aatctgattg gttttacgga ctcgcaaact gtctagttgc ttcttagttt
     7501 taaaggattt agccgtatat aagcatagct attgtcctcc agaaaggcct gaagacgaga
     7561 atagacccct gtgcctcgaa gataatctca ggtgtattta cctatttcaa atcctctaga
     7621 agacgactaa atccgatggc atcattgggc atggtatagc catgaacctt ttcaccattc
     7681 acaagaatag cgacttctga gcttgcctta ctcacatcca ttctgaaaac tgtccgcatc
     7741 atgtttaccc ctttgtcttg aatgactcct tgttttagtg attttatttc caatactcga
     7801 cgtctagtat cccacatact ttgataaaat tcttcctaaa acaggtttct tgccagtttg
     7861 tcaagcgacg tctagcacca tagagagctc tatgacttaa caagacacca ctattttaac
     7921 acaaagaaaa agtaatgagt actctctccc gttggagatt tcctcactac taatcttagt
     7981 atgtttgtca actgtagtga tagacgaata atcaagttct ggagaaggtc agattgggcg
     8041 attacttatt attttcctag cttgtacggt gcttttatcg ctatgaaaaa gtttattcca
     8101 aaatcttttt ttagtaactt atagcttact tactgttata ccaactattt ctaaaatctt
     8161 ataaattatt ttatgcatat tttgcataaa attccaaatt tgataatctt caaattacaa
     8221 tattagtaag aggattatta atgtatatca gattaaagaa tttaagagaa gacaaagatt
     8281 tgtcccagtg tcaaattgca cagtatcttc attgttcaca gtctgcttat tctagaatag
     8341 aaagtggcaa gcaagatatt cctacatcat ttttgaaaca attagctaaa ttatatcagg
     8401 taactacaga ttatatttta gagatggata agtttagttg ttaataaatc ctaagccctt
     8461 tgaaaactga ataaaccgag gtgggacttt cttatttgtc gagcacttta gcttgatacg
     8521 ccgtgatagg agcgataatt attagctata aaatagagtg gttctctatc tgccatgact
     8581 acaaataagg ataatgatac ttctgaacgt tcaggctgcc agcgaaaaag gacagcgggt
     8641 gaaatgccca tgaatgattt aaccagtcat acccacggag gaaattatac atgttacaag
     8701 gaggaaaaag tttggaacaa tcagtaataa agtatactat gcaactatca atgcttaact
     8761 ttttatactc aagaaatatg ttatctaaaa atgagtatga caagattaga aacaaactgc
     8821 gtattaagta cacaaaatag ctgacttttt gatttgaatg cggtaatata gaatcaaaag
     8881 gaggaatttc agtatgaaaa aaaataatgt tgaaataata aaagctgatt ctttagttcg
     8941 tcgaagaggc gacaatgtag aaagacactt aaagagggtt gctgcttatt gcagagttag
     9001 ttccgatagt gaggatcaga aaaacagtta tgattctcaa gtaagacact acaaagaata
     9061 tatttctcag cgttcagatt gggagctggc agatatttat gcagatgaag gtatttcagg
     9121 aacacaagta ggaaagagac aagattttca acgattaatc aatgattgtg caaatggaga
     9181 gatagattat attgtcacaa aagcaattgc tagatttgca aggaataccc tagatacttt
     9241 gaagtatgtc agaatgttaa aggatatgca aattggagta tattttgagg aagaaaacat
     9301 agatacccta acaatggatg gagaattgct tctaactatt ctaagctccg ttgcacagca
     9361 agaagtagag aatacttctg cccatgtgaa aaaaggatta aaaatgaaga tgcaacgtgg
     9421 tgaattggtt ggttttcaag ggtgcttagg gtatgattat gatgtagaaa ccaagcagat
     9481 ttcaattaat aaaaaagaag ccaaaattgt tcgttatatt tttgaaaggt atctagaagg
     9541 tattggagga aaagtaattg caagggaact tgatgaactt ggttacaaat cgccaagagg
     9601 tttagaacac tggaatgata caacagttct aggaataata aagaatgaaa aatataaagg
     9661 tgatattcta atgggaaaaa cttttacagt tgacccaata agcaagagac ggttgagtaa
     9721 ttttggagaa gaagataagt actatatcaa ggataatcat gaaccaataa tatctaaaga
     9781 agattttgaa aaagctcagg agattagatt gcgtcgagca ggaaataaga agacagctgc
     9841 gaatgtaaat gggaagcgtg aacgctattc aaaaatgtat gcttttagta gcatgttgga
     9901 atgtggtttt tgtggttcaa tattatctag aagaagttgg cactgccgtt cagattatcg
     9961 caaagttgtg tggcactgtg ttacatcgat aaagaaagga aagaaatttt gtaagcatag
    10021 taaaggatta gaagagatcg ccattgaggg ggctttcctg gaagcttaca gacaagtcta
    10081 tcattcaaat gaaaatttaa tgacagactt acttgaaacg atagaatctg aattgaatga
    10141 caatagcctt aacaaggaac taaaaaggat tacaaacaaa cttcgaatat tactaaaaaa
    10201 agaggagaat cttgtaaatc taaggctcga aggaaaagtt agcgattcca tatacaatga
    10261 aaagtacaat gaaatttcct cagaaaaaga gtttctagca gaagagaagg taaatattga
    10321 aacaacatta aaatcagaaa tcgatgtaaa gaaaagacta actgagttta agcacttgct
    10381 atcttcgcaa aaaatgctta cggagtttga tcgtgcagtt tttgaaagta ttgttgagaa
    10441 aattattgta ggtggagtta atagcaacgg agaaattgat cctgcaatgt taaccataat
    10501 attcaaaaca ggtgaaattc aaaacaagga tggtaaacaa tttaaaagta aacgtaaaaa
    10561 tgctaaacta gaaacagata aattgtgtcc tcaaaacagt gacgaggata aaaaattgta
    10621 ttctcaagga acagacaaca cacgtggagt gtgtagtgtt gctggttcga tcttagccag
    10681 tcaataaaat gatatgtttt aaaaaaatta taatttcgaa acgtgaataa acttgtttaa
    10741 actttatgta tctttagaaa gtgtgttaac ttgaaagaac aaattttttt gatgggtggg
    10801 aatcccccaa taaagaaata tagtattgtt gataaaattg tattatcaac caagattaaa
    10861 agaattatca tttttacagt ttttcgagaa aattgggaac cgtacatgaa aaagtacacg
    10921 gaagtttttc aaagtcaatt tcctaatcta aacattgatt acttgctcct ggacactgag
    10981 cagattgatc ttgatagcta tctagatgct gacataatta tcatcggtgg tggaaatacg
    11041 gaaaaatata ttgctactta tattaatcag gagttcaaaa gttatatcga tcatatgctt
    11101 aataaagagg caaaaattat aggattttct gcaggacccc tactattagg agaaaaagtc
    11161 tatgtctcac ctaatgataa ttcagatcat cagataaaga taaaaaatgg attaggactc
    11221 tttagtcagt ttttaattag tgtccattat gattcctgga atgataaagc aaataaggat
    11281 agagctgaag aactcgataa tgttcccata attccactaa atgatcattc ttgtcttgta
    11341 ttggataaac ttggaaacat catagagaaa attgactaac tttcataatg taaaaatgga
    11401 tctaggaaat aaaagtgtag acgaactgga taggttacta gtgaaaactg caaaaagtgt
    11461 tgtaaagtga atcggagtgt gcttgatgga ttttagtagt aagatagcca taaataaagg
    11521 ctggtcagat gataaaaaat attgtgtgac agatcaaaat cagtaaaaat atttcttgcg
    11581 tgtttctgat aagtcgaagt tagattataa aaaaatttga atttgatatg atggagaaag
    11641 tagcttctct tggagttccg atgtgtaaac caattagcat tgaactctgc gatgacgaag
    11701 tacattcttt acacgaatgg atagacggaa gagatgcaat agatagcatt ttaacttatt
    11761 cagaaaacca acaatacaca tatggtgtag aagcaggaaa gatacttaga aagattcata
    11821 caattcctgc tacagaagtt tgtgaagatt gggaaatctt ttttaatcta aaaattgatg
    11881 ataaaatctc caacgaaatg atatggtaag tccgaaacgc tcagtgtgta agcttgttgc
    11941 taaaagcgta aaaaccttgg aacgaaagga ataatagact tcctgcgaaa caaaaataca
    12001 atacaataaa actatggatg atgaagcaag taaacaatta agcgatagcc gtttcaagag
    12061 ccttgtaggt gttcagcgca cgagatgtta gctgtgttaa aaacagctta tcaacgcaac
    12121 gtaaacgcgc aaaaggtgga cgaaaaacca aattaagcct agacgatctc ctcatggtaa
    12181 ctattcaata catgcgagaa tagcgcactt atgaacaaat tgcggctgat tttggcattc
    12241 acgaaagcaa cttaatccgt cggagccaat gggttgaagt aactcttgtt caaaatggtt
    12301 ttacgatttc aaattctgcc ctaattatga aaaacagtaa aattcgaagg attgtaaggt
    12361 aagagttttt ttctttctga aaaaatggta taatagcaat caaaactaga aaataaaacg
    12421 gaatttggaa cagatttgtc tgtatcctag tagagtggtg atgctatgaa gattagtaag
    12481 aggcacttat taaattattc catcttgatt ccctacttgc ttttatctat tttgggcttg
    12541 attgtggtct attcgaccac cagtgctatt ttaattgaag aaggcaagag cgccttgcag
    12601 ttggttcgaa accaaggaat cttttggatt gttagtttga tactgattgc cttaatttat
    12661 aaattgagac tagatttttt gagaaatgag cgactaatca ttttagttat attaatagaa
    12721 atgcttttat tgttcttggc tcgttttatt ggtatttccg taaacggggc atacggttgg
    12781 atttcggttg caggaataac tattcagcca gctgagtact taaaaatcat tattatttgg
    12841 tatttagctc accgattctc caaacagcaa gaagaaatag ctacttatga ttttcaagtt
    12901 ttgactcaaa atcaatggct tccccgtgct tttaatgatt ggcgattcgt tctcctagtt
    12961 ctgattggaa gtttgggaat tttccctgat ttaggaaatg cgactatttt agtcttggtt
    13021 tccttgatga tgtatacagt tagtggaatc gcttatcgct ggttttcaac cattctggcg
    13081 ctcgtatctg ccgcttctgt ctttgtcttg accactatca gcctaatcgg tgttgagacc
    13141 ttttcaaaaa ttccagtatt tggctatgta gccaagcgct ttagtgcctt ttttaatcct
    13201 tttgccgatc gtgctgatgc aggtcaccag ttagctaatt cttattttgc catggtcaat
    13261 ggcggttggt ttggtctagg tcttggaaac tcgattgaaa aacgaggtta tttgccagaa
    13321 gctcatacag actttgtctt ttctatcgtg attgaagaat ttggctttgt tggtgccagt
    13381 cttattttag ctctcttgtt tttcatgatt ttgcggatta tcttggtcgg tatccgagcg
    13441 gagaatcctt tcaatgccat ggttgcactc ggtgtcggag ggatgatgtt ggttcaggta
    13501 tttgtcaata tcggagggat ttcgggcttg attccatcta caggagtgac tttccccttc
    13561 ttatcccagg gtggaaatag tcttctagtc ttatcagtgg cagtagcctt tgtcttaaat
    13621 attgatgcca gtgaaaaacg cgctaaattg taccgagaat tggaaaatca accaatgaac
    13681 cttctgttga agtaggataa agaaaggata gtttatgtct cttcaaaaat tagaaaatta
    13741 tagtaataaa agtgttgtgc aagaagaagt cttgattcta acagaattac tggaagatat
    13801 tactaaaaat atgcttgccc cagagacctt tgaaaaaata atacagttga aagaattatc
    13861 aacgcaggaa gattatcaag gtctaaaccg tctagtgact agcttatcaa atgatgaaat
    13921 ggtctatatt tcacgctatt tctctatctt gcctcttttg attaatattt cagaggatgt
    13981 ggatttagct tatgaaatca atcatcaaaa taatattgat caggactatt taggtaaatt
    14041 atctacaacg attaaattgg tagcagaaaa ggaaaatgcc gttgagatcc tagaacactt
    14101 gaatgttgtc cctgttttga cagcccatcc aacacaagtg caacgcaaaa gtatgttgga
    14161 tttaacaaat catattcata gtcttttgcg taaataccgt gatgttaagt tggggttgat
    14221 caataaagat aaatggtaca atgatttgcg tcgttacatc gaaattatca tgcagacaga
    14281 catgattcgt gagaaaaaat taaaagtgac taacgaaatc acgaatgcta tggaatatta
    14341 taacagctcc tttttgaaag ctgtacctca tttgacgacg gagtataagc gcttagcgca
    14401 agcgcatggt ctgaatttaa aacaggctaa accaatcacc atgggtatgt ggataggtgg
    14461 tgaccgtgat ggaaatccat ttgttacagc aaagaccttg aagcagtctg cactcactca
    14521 gtgtgaagtc atcatgaact actatgataa aaagatttac caactttatc gtgaattttc
    14581 tctttcaact agcattgtca acgtcagcaa gcaagtcaga gaaatggctc gtcaatccaa
    14641 ggataactcg atttaccgcg aaaaagagct ttaccgtcgt gccttgtttg atattcaatc
    14701 aaaaattcag gcaactaaaa cctatctgat tgaggatgaa gaagttggga ctcgttatga
    14761 aaccgccaat gatttctaca aggatttgat tgccattcga gattctctac tagaaaataa
    14821 gggcgagtcc ttgatttcag gtgattttgt ggaattattg caggcagtag agatatttgg
    14881 tttttactta gcatcaattg atatgcgaca agactctagc gtctatgaag cctgtgtggc
    14941 agaactcttg aaatcagcag gaattcattc tcgttatagc gagttgagcg aagaagaaaa
    15001 gtgtgacctt ctcttgaaag aattagaaga agatccccga attctttctg cgactcacgc
    15061 agaaaaatca gaattattag caaaagaact agctattttt aagacggctc gtgttttgaa
    15121 agataagttg ggagatgatg tcatccgtca gaccatcatt tcacatgcaa ccagcctttc
    15181 tgatatgcta gaattagcta ttctgttaaa agaagtagga ctggtggata cggaaagggc
    15241 gcgtgttcag attgttcccc tttttgaaac aattgaagac ttggatcatt cagaggaaac
    15301 aatgagaaaa tatctttctc ttagccttgc caaaaaatgg attgactcac gaaataacta
    15361 tcaagaaatc atgcttggct actctgacag taataaagat ggcggttact tgtcatcatg
    15421 ttggaccctc tacaaggctc aacaacaatt gactgctatt ggagatgaat ttggcgttaa
    15481 ggttaccttc ttccatggtc gtggtggtac tgtcggtcgt ggtggtgggc caacctatga
    15541 agccattaca tctcaaccgc tcaagtctat caaggatcgt atccgcttga cggagcaggg
    15601 tgaagtaatt gggaataaat acggtaacaa agacgccgct tactataacc ttgaaatgct
    15661 agtatcggca gctattaacc gtatgattac tcagaagaag agcgatacca ataccccaaa
    15721 tcgttatgaa gccattatgg atcaagtagt ggaccgtagt tacgatatct accgtgattt
    15781 ggtctttggt aatgagcatt tctatgatta tttcttcgag tcaagtccaa tcaaggctat
    15841 ttcaagtttt aatattggtt ctcgtccagc cgctcgtaag actattactg aaatcggtgg
    15901 attgcgtgct atcccttggg tattctcatg gtcacagagt cgtgttatgt tccctggatg
    15961 gtacggggtt ggttcaagct tcaaggaatt tatcaataaa aatccagaga atattgctat
    16021 cttacgagat atgtaccaaa attggccttt cttccaatcg cttctttcaa atgttgatat
    16081 ggttttgtca aaatcaaata tgaatattgc ttttgaatat gctaaacttt gtgaagacga
    16141 gcaagttaag gccatctatg agactatttt aaatgaatgg caagttacta agaacgttat
    16201 cttggctatt gaaggacatg acgaactctt agctgacaat ccatatctaa aagctagtct
    16261 ggattaccgt atgccttact ttaatattct caactatatt cagttagagt tgattaaacg
    16321 ccaacgtcgt ggagaattgt ccagtgatca agaacgattg attcatatca ccatcaacgg
    16381 aattgcgaca ggattgcgta attcaggttg ataattttca agagtgaatg ctaaaagtga
    16441 atatcaaaaa aattctaata gactattgac aagtagttta aaaatgatat aatttaacca
    16501 ttcagaaaag taatcataca aactttttag agagtctgtg gtagctgaaa acagataagt
    16561 ggcaatgatg aaaattgggc tgaatgctat ttagaatttg aaattataaa aattcggtaa
    16621 gcacacctta cagtgcatct cgttattgcg agactgagcg atagggaaat tccctataat
    16681 tgaggtggta ccgcgcatcg acgtcctcac acaagttttt tgtgtgagg
//
LOCUS       DAVKEV010000046        16272 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVKEV010000046 DAVKEV010000000
VERSION     DAVKEV010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16272
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.046"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(214..2319)
                     /locus_tag="VWZ68_001709"
     CDS             complement(214..2319)
                     /locus_tag="VWZ68_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU9372701.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSQLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     TKHLEADMEDGVLVIREKA"
     gene            complement(2928..3908)
                     /locus_tag="VWZ68_001710"
     CDS             complement(2928..3908)
                     /locus_tag="VWZ68_001710"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEU9372702.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(3910..6162)
                     /gene="pbpX"
                     /locus_tag="VWZ68_001711"
     CDS             complement(3910..6162)
                     /gene="pbpX"
                     /locus_tag="VWZ68_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEU9372703.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(6166..6483)
                     /gene="ftsL"
                     /locus_tag="VWZ68_001712"
     CDS             complement(6166..6483)
                     /gene="ftsL"
                     /locus_tag="VWZ68_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEU9372704.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(6495..7445)
                     /gene="rsmH"
                     /locus_tag="VWZ68_001713"
     CDS             complement(6495..7445)
                     /gene="rsmH"
                     /locus_tag="VWZ68_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEU9372705.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            7611..7805
                     /locus_tag="VWZ68_001714"
     CDS             7611..7805
                     /locus_tag="VWZ68_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9372706.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            7821..8363
                     /locus_tag="VWZ68_001715"
     CDS             7821..8363
                     /locus_tag="VWZ68_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEU9372707.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNIIPLLLAYKYPQEVALIYPPLILVIALIASGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            8374..8616
                     /locus_tag="VWZ68_001716"
     CDS             8374..8616
                     /locus_tag="VWZ68_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372708.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            8627..8962
                     /locus_tag="VWZ68_001717"
     CDS             8627..8962
                     /locus_tag="VWZ68_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372709.1"
                     /translation="MKSLARLLIIHVFISIFLFFALTSGAISHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(9072..10073)
                     /locus_tag="VWZ68_001718"
     CDS             complement(9072..10073)
                     /locus_tag="VWZ68_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9372710.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(10133..12034)
                     /locus_tag="VWZ68_001719"
     CDS             complement(10133..12034)
                     /locus_tag="VWZ68_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEU9372711.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHYSKDYEKVKRSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKSYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIRVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(12056..12349)
                     /locus_tag="VWZ68_001720"
     CDS             complement(12056..12349)
                     /locus_tag="VWZ68_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU9372712.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(12349..13167)
                     /locus_tag="VWZ68_001721"
     CDS             complement(12349..13167)
                     /locus_tag="VWZ68_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9372713.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            complement(13154..13933)
                     /locus_tag="VWZ68_001722"
     CDS             complement(13154..13933)
                     /locus_tag="VWZ68_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU9372714.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            complement(13948..14439)
                     /locus_tag="VWZ68_001723"
     CDS             complement(13948..14439)
                     /locus_tag="VWZ68_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU9372715.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(14450..15640)
                     /locus_tag="VWZ68_001724"
     CDS             complement(14450..15640)
                     /locus_tag="VWZ68_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEU9372716.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(15652..16086)
                     /locus_tag="VWZ68_001725"
     CDS             complement(15652..16086)
                     /locus_tag="VWZ68_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9372717.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
BASE COUNT         4744 a         3671 c         2868 g         4989 t
ORIGIN      
        1 tacaataaaa taggctccat aatatctata gtggatttac ccactacaaa tattatagaa
       61 ccgttttttt cagctggctc cttctttttt atcctcaaaa ttctatctta tactcaatga
      121 aaatcaaaga gcaaactagg aaactagccg caggctgtac ttgagtacgg caaggcgacg
      181 ttgacgtggt ttgaatttga ttttcgaaga gtcttaggct ttctcacgaa taaccaaaac
      241 gccatcttcc atatctgctt ccagatgttt agtatctaaa tgatccaagt ggaagtctgt
      301 caccttatca cgaatttctt gttcaaccac gcgacggaga ggacgaaccc ccatgacttc
      361 gtcgtaacct tcttctgtga tataatcttt agccgcttga ctgactacca agtcaatgtc
      421 tttcttagcc aaggtttggt taacttcagc caacatcaaa tctacaatct tagaaaggtc
      481 ttccttagtc aattgtgaga actcgatgac tgcattaaag cggttgagga attctggacg
      541 gaagaagggt ttcaaacggt ccatcaattc tggtttatcc gcatcttctg tcaagttggc
      601 ttcatagcca aatccagcat ttgaggtcgc aataatgaca gtgttcttga agtttactgt
      661 atttccttga ccatctgtca aacgaccatc atctagaact tggaggagaa gggtaataac
      721 ttgaggatca gccttttcaa tttcatccaa gagaatgata gagtatggat tgcgacgaac
      781 acgttctgtt aaggtattgc tattgtcatc ataacccaca tagcctgctg ttgtaccaat
      841 tagcttagaa acagctgtgc ggtcactgta ttcagacata tccaaacgga taatcgcatc
      901 ctgggttcca aacatatcga gtgccaattg cttagcaagc tccgtcttac caaccccagt
      961 agaccctaca aagaggaagc tgccgattgg gcgatttcct tcatcaaaac cagcacggtt
     1021 acgacggata gcgcgagcta cagcttctac ggccttatct tgaccaatca ccttgtcttg
     1081 caagcgatga gccatatctt tcaaacgttc gatatctgaa gctcccattt gcgatactgg
     1141 gatacctgtc attcgttcca cagattcagc cacatcgttg acacttgcag tcactttcat
     1201 atcttctgtg tggttttcga ttttcttttc caattctgca atgcgtgttt tatagtttag
     1261 agctgcttca aaatcttctg cttcaactgc tttttcttgc ttgtcttttt ccgtttcgat
     1321 ttctcgttca acagcatgca catctgttac tggatgttga gccgccaagt gagcagccgt
     1381 tacatcgaca aggtcaatag ccttatctgg caagctacgt tgaggaatgt attgaacaga
     1441 ataatccacc gctgctttca agacttcgtc tggcaagatg acattgtggt gttgttgata
     1501 gaggtcacga attccttgaa gaattttaaa agtattctct gccgaaggag cattgacctt
     1561 cacttcgttg aaacgacgag caagagcagc attcttcaag atggtgttac ggtattcgtc
     1621 ttgagttgtt gccccaatca ctgtcaattc tccacgagag agagctggct tgagaatatc
     1681 cgcaagtcct ttagaaccac tgtctccacc agtgctacca gcaccaagaa tttggtgaat
     1741 ttcatcaaag aagaggataa tattccctgc ttctttcact tcattgacta agttttggac
     1801 attttcttca aagctaccac ggtattgagt accagcctca agacctgaga tatcaataga
     1861 aataatttcc ttgttcttga tagcagcagg aacatctccg ttcacaatgg cttgcgctag
     1921 accttcgaca actgctgtct taccaacacc tgcatctccg accaaaacag gattgttctt
     1981 ggtgcggcgt gagaggattt cagatgtttc ttgaatttcc ttgtttcgtc cgataacagg
     2041 atccaacttg ccctcacgcg cttctgctgt taagtttcga cctagttttg caaggacacc
     2101 gtcttgtttc atacctgatg cctgttgtgg catttgcaca tcagtttctg catttcctgg
     2161 taattgacca gtcgcacgat agtgagcaaa ttcctcaggt gtgacttcgc gtccattaat
     2221 taagtaacgg cgattttcag aactgtatcc tcgcatacca cccatcaatt ggttaaataa
     2281 atcatccatg ttattaaaat tattaaagtt gttattcata ttctttacct ctttttgttt
     2341 acttagttat gattactgat attgactatc tttgaccatt gttttaaaaa atttagacta
     2401 gctagatcgc taccctacgt actatttctg gtttttcttt ttcaagcagg agtagactat
     2461 ctttacttct gaagatttct agatgaaaca tagacccacc tctttctatt ttactttaaa
     2521 taagtgttct agtaaggctt tcatttacct tacgttcata atatactaca ttggtcagaa
     2581 aaggtcaaga gttttgactt taactgacca atattttttt acactcttcg aaaacctctt
     2641 caaaccacat cagcttctcc ttatctacaa cctcaaaacc gtgttttgag ctgacttcgt
     2701 cagttctatc aaccatctca aaactgtata ttaaaacgaa ataagaacag gacaaatcaa
     2761 tcaggacagt caaatcgatt tctaacaata ttttagaagt agatgtgtac tattctagtt
     2821 tcaatctact atattttgag cagcctaaag ttagctttct agtttgttct ttgattttca
     2881 ttgtgtattt aaacacaaaa acaccctgaa acatcagggt gccattctta catcaaatat
     2941 aaaattgcta gggtcaggag acttgctaga agtcccactc cccaaaagaa gaagtcaacc
     3001 ttccactcgc tccaaggatt tcctttacca gacaatcccc caagctcaaa atggtgatgt
     3061 acaggcgtca tacggaaaat acgtttacca cctgtcagtt tgaaataact gacttgcatc
     3121 ataacagaag ttgtttcaaa aacatacaca attccgataa tcaagagagt ccattcttgg
     3181 tggagagcca tagagatagc tgccagcatc ccacctaggg ccaaacttcc cacatcaccc
     3241 ataaagacct tggcaggctt atggttaaag atgaagaaac cgagcaaacc accaatcatg
     3301 gcaagaatca ctagaagaat atccatctga ccttgcacat aggcaataac tccataggca
     3361 gacaaactaa tcacaacgga aatactagct aaaccgtcaa caccgtctgt caagtttact
     3421 gcgtttgaaa aaccgactag ccagaaaaga gcgaagaaaa tatagaaaaa tcccaaatga
     3481 actggataac caaagacaga caggatatcg ccaccgcgct catagaaaag atagaagata
     3541 actccaccta gaagctgaag agctaatttt tgcttaggat taagcccctc attgatttta
     3601 cgaaagacct tgagaaagtc atctaaaaat ccgaccaagc catacaagac caagatgaac
     3661 aaaatcattc ccacattatt gctgaattgg ctactaaata gggcgaaaaa gaaagcaacc
     3721 aaaacagaag taatcaagaa aaccaaacct cccattgtag gagtcccagc ttttgcctga
     3781 tgctgtttga catcttcatg catctgctgt cctgtaattt gcgcctttct ataaaattgg
     3841 ataaaggccg gaattcctac taaagttagt aaaaatgtca caattccagc actgatggaa
     3901 ataaacatat tagtctccta aagttaatgt aattttttta atgtccttga tagctgtgtt
     3961 agcacgaaca tcttgcttct gcacagtaga gcccgaacct tgaaattcaa gttctatatt
     4021 gagccactta gcaagggtct cagcagtctc ctttgtccaa ccatacatat ctggaacttc
     4081 ctctgcttta tcagataaga taaggacttg ctgattcggg gcaagattct tcccttcttc
     4141 agcagaactg tttttaatct tcgttcctgt tcccacaacg atgggttgta caagattgcg
     4201 acgcaattct tctgctaaat caccaggtga aatatccttg acactaggca taggataagg
     4261 actttgttga cttacttgct ccaaagcttt agctgttgtt tgaagattga gagagtcttt
     4321 catagctgaa gcccgctcca agataggatt ggcaaattct cccaactgaa tacctgaata
     4381 atgttcaggt tgttggaccg tcacatacaa gataaaatca ggattttcag ccggactcat
     4441 cgatacagcc gagaaaatat agtcggttac cccgactaga taaccaccat ttttctcgtc
     4501 agcaatctga gccgtaccag acttgagggc tacattttgc ccaggaacag ttacagttgg
     4561 cttgcctgtg ctgtggttat acatggttcc ataaaccgga tccgtcccta ccaaaaccat
     4621 gttagtccga gttagactag ctgcatcttt agaaacagga tttcccacaa tttctttttg
     4681 agatttccga gcagtttgat catttggatc ataaatggca ctaataaatt taggctccag
     4741 catgacaccg tcattagcaa tagctgtaaa ggcacgaatc atttgcgtct gggtcactga
     4801 aatcccttgt ccaaatgagc tttgcgcaat gttgacaata ttatccgcag gaagctgacc
     4861 agcatactca tccgtcaaac cgaaacgggt cggaactcca aatttaaaac gattaagata
     4921 atcaagccag gtagcatctc ccatcttttg ctcaaggagg gtcatcccaa cgttacttga
     4981 gtgtgcaaaa ccttgagaaa aagtcatcat tctgccacca gtcaatcctt cattaacgtc
     5041 ccaatctcga atcgtggcat ctgcaatttt taactcacta ctattaaaga cttctcctcc
     5101 tggaaaggta ttattatcaa tagcagcagc caacatcatc actttcatag tggaacctgg
     5161 ctcatagtta ctttggtaaa ggatatcacg ccaaacaaag tcctctgtaa tgccttcttt
     5221 tgtatctgca tcaaaggtcg gtcgttgcgt tgttgccaga atttcccctg ttttagcact
     5281 gaccaaagtc gctgtcatgt actttccttt taccttctct tgaaaagcat ccatctgggt
     5341 ttccataaag gactggaggg ggctggaaat ggttgtataa acatccttac cgtccatcgt
     5401 tcgttgggaa acttgttctg ttccgggtac aatattaccc agacgatcct tttcataggt
     5461 aataatgccg tctgtccctg caagaatact gttcaaggaa ctctccattc cagaggttcc
     5521 cagcaagctc ttgcttccat cttcattttc atggagctga gctaggccga taaaactaga
     5581 agcaaattgt ccgtttgggt aactacgatt gggactggtt gtaaaatcaa tccccttgac
     5641 ctctgcagct tccaattctt ttttgataga catcatattg gcataggtaa tcccatttcc
     5701 ctttgctcca aaggaaactt gcttgagatt aggttgcgag agttgctctc ttacatagga
     5761 ttcttccatg tccaaatact tatgaaagac ctctgcaacc ttgttaaatt gtgttttttc
     5821 tacgtaaaga atcttacccg ttgctgactt atagttctca tcaatgaccg catagacatt
     5881 ataggaggtt gcatcctcag caatcgggac tccatttcgg tcataaatag tcccacgttt
     5941 ggcaggaact gtacgggtgg tttgatgaac tttcttagct tccttcgcta aatctgttcc
     6001 aaagcgagtg cctgtcccaa taatgaccgc aaaattgact aaaaaaatgg caaaaacaaa
     6061 gacagataat aaactcagac tttttccaac tctgcgtctg ttttcagccg gcgatttccg
     6121 atttttggtc gcataacgga ttactctttt tgtccacttc atatcttact ccgctattct
     6181 aatattttca ttgtttaatt gcaaatcgtg tgaattggca atttctttca aacgttctgc
     6241 acgtaatagt tcattgacct cttgcttggc atcgtccaat tcggttttct tttcctctat
     6301 ctgcgcattg atttttgtca aatcattctg cacttgcaag agcttggtct gcataaaaat
     6361 aatactaatg gctacaataa gagtggttac agcaatggaa aagtaaaaag ctttttccac
     6421 acgcgaaaac cgtttaagtt gcatctgtag tatttgacct gttttttcca ttttttctgc
     6481 catctttttc cctcttactt gtgaattttt ctggccacgc gcaacttggc tgagtgcgag
     6541 cggttattgg cttctaactc ttccgcactt ggcaagattg gcttacggga caccaattcc
     6601 atcttgggct tgagatcatc tgggatgaaa ggcaagcctt ttggaacttc aactgttgaa
     6661 gcttccttga acaattgctt ggtcaagcgg tcttctaagg aatgaaaggt aatcactgaa
     6721 attctaccat ccagagccaa catatccata gcctgctgga tggactcatc tgccgccccc
     6781 agttcatcat tgacttcaat tcgaatagcc tggaaaatct gcttagcagg atgccccttc
     6841 ttcttgagtt ccttggcagg tttgaccaac ttgataatct ctgctaactc agtcgttgtc
     6901 tcaatcggct tcacttcacg cgcttgctca atcttacgcg caatctgttt agagaatttg
     6961 tcctctccat acttgaagaa aatacgaacc aagtcatgat agtcataatt gttcaccact
     7021 tcatacgctg tcagactagc atcctgattc atccgcatgt ccagtggcgc atccttttta
     7081 taagaaaaac cacgctcacg ctggtctaat tgaggactag acactcccaa gtcataacaa
     7141 attccatcaa tttcctgaac accagcttcg cgcaaacgtg cctgtaaatg acggaagttg
     7201 tccttgataa aggtcaccat tcccttctca atgtaaggtg ccaagcgttt ttgcgcattg
     7261 tcaatggcat tctgatcctg gtcaaaggca tagagatggc ctttttcact taatttactt
     7321 aataaatact cgctatggcc tgctccaccc aaagtcgcat caacgtagat accgtcaggt
     7381 tttacgtcaa gcatatcaat cgtttcgtgg agtaagaccg ttacatgatg aaattctttt
     7441 gtcatatctt atctatttta ccacaaatcc gaccagcttg cacttgtcag acaaatagga
     7501 caaggagact actatttctt caaaaaatat gtcaaaaata cttgacactt tatgtttaaa
     7561 agactataat atagtcaaat atatacgaca taaatcagaa aggagaccag atgaatcgtg
     7621 tgaaagaatt tcgcaaggaa ttgggtattt cccagctcga actcgccaag gatatcggtg
     7681 tctcgagaca gactatcaat atgattgaaa acgacaagta caatccaacc ttggaactct
     7741 gtctcaatct cgcccgcagc ctccaaactg acctcaacag tctcttttgg gaggaagatt
     7801 tttaaaaaag gagcaaactc atgaaaaaag aaaccttcac tgaaaaactg atcaaacgca
     7861 catacggtat ttctggtccc cttgacgaat acaaacggcg tgaggccgat agtattggga
     7921 accaagtctt tatcgtcctc ttttatctga tgattttcgg aaatattatt ccactccttc
     7981 tggcctataa ataccctcaa gaagtggctc taatctatcc tcctctgatt ttagtgattg
     8041 ccctcatcgc ttctggctat gtcacctacc aaatgaaaaa aacaggcatc acagtcattg
     8101 aaccagatat gctgaatgag aaagaaagca agcaactaca ctaccctggt ctgaaagcag
     8161 gtttgttctt tggtctatgg atgtttttta taactcctct tctcagtata ctcatagatg
     8221 aaggtcagga ctattttcat tctcttctca ctataagaaa tggtgtatca agtattctcg
     8281 gttctatttt cttcggagcg agcatacagt tcctcatctc ccgtcgcatt gcaaaaacta
     8341 agaaaaatca agatgaggat taggaggaaa ctcatgaaaa aagaaaagaa acagttacgt
     8401 tatcctggtc tgaaagcagg ttcgatttat ggaacagtga tattttttat aattccactc
     8461 attgataccc taacaagtga aaatccaaat tttatcagtt ctcttctaaa tacaaaacat
     8521 atttttaaaa ctatactggg agctttcttt ttcggagtga tgatacatat tgtcgactca
     8581 cttcgtattg caagagctaa aaaagaccag gattaggagg tgccttatga aatcactagc
     8641 tagactactg atcattcatg tttttatcag tattttcctt ttcttcgccc ttacttcagg
     8701 agctatttct catacagttt tactactcct actcctcttt cttcctgcgc tcaataaagg
     8761 acttgagaaa atacaatcaa aacggatacc tgtcctcaac gcagccctct tctttctcct
     8821 catatccttt ccacaacttt taaccaaccc tgtccaatgg aaattttcaa tattcctagt
     8881 cgtaaccatc atttcaagtt tggcctactt ctataacttt tatcaagtag ttaaagaagt
     8941 agatcaaaaa cagttgattt aggagcttgc tcccataatt tctcatttta taggcaaata
     9001 atcccaccta gcttgttcta ggtgggatta ttttatttct taacagagat tgcaagtcat
     9061 tttccttcat tttagaaagt cgactctttc caattcacac tacaatccaa gacttgttgc
     9121 ctttcttctt gattgcgacc ttcaatctgg tcaatcaaaa tctttgtagc ctgttgtcct
     9181 tcctcaaagg agggctgaac cagcgtcgaa acacttggag aagaaaagca agtccactcc
     9241 gtattgtcaa aaccaatcaa cccaacttgc ggcaagttat aattcaactc tttgataacg
     9301 gtaaagacta gaggtagggc ccaacagtta gggataaata ccagagtttt ttcatcggga
     9361 tcgatttctt tttgtaaaaa ttctttaatt tgttccaaat tcgtatgctt atcttcaatg
     9421 gttagactgg cgtgacgcat attagcatct gttaaagcat ccacaaaacc acttgcccgc
     9481 tcaatccgag tactcaaacg actcgtatcc gctgtaatca agagaaaatg ttcataacct
     9541 ttttcgatac aggactgggt catgtcataa acggcatcat agttattggt tttaacccag
     9601 ctagtccggt gttcatagag ctgactatca aaaaagacca ttttcttctt tttctcatcg
     9661 atgatacgag aatattttcg gaaattagag gtcggctgaa taataaagcc gtctactccc
     9721 aagagaagca tgctttcaat ataccggtcc tcactctctt ggctgtaatt actatttcct
     9781 atcattacct ggtagccatt ctggctggcg atatcctcaa ttcccttaac aatttggttt
     9841 gagaaactgt tggtaatatc accaatcaaa acaccgatta attttgttcg tttggagttt
     9901 aagctacgcg caacaatgct cggtttgtaa tttgtttcat gaataacttt ttcaatcttt
     9961 tcacgtgtct cttgggacat tttttcatat ttcccgttta ggtaaaatga cacggttgtt
    10021 ttcgaggtct gagccatttc cgcaatgtct tttatggtca gtttcttctc caatctaaaa
    10081 cacctcctac taatacttat tataacatat tcactattca aaatgcctat ttctagcact
    10141 gcaagcgaat cattctctca tttattttat catatactag acattttcca cgcatttttg
    10201 ttccgtcaac gaggcacaat ttttcaccta cacgaatatc ctcgcttaat aacagaatca
    10261 gcttgtctgt ttcgtcattt ttcacttcaa aagccagagc attttccact tcacgatcat
    10321 ctgtctggta gacagaatga cggatgattt caaaactctc atgcgcaatg atggtataat
    10381 ccagcatctg attctcaaag aattggcgct tggtgagttt gctacttctt tcaagctcat
    10441 tgtatttagg agaaatgatg gtatcttcca aatcaaaatc aacttcactc catagtctca
    10501 actgattgat tttcccatct tgataggtca catccttgtc aaggataaac tgagtcaacg
    10561 cctcatgctg accttgacac ctgatgtcat ctaccaagag ccagacatcc tctaccaaca
    10621 tgaggatttt tctcttgtga agataaggca aatcaggttc tgctgaccaa taagcccctt
    10681 caatataatg cactccctcc ctttctttat ggtgacaaaa cagggagtga ggatagtatt
    10741 catattccca ggatcccgtg attctttccg gagctttccc atctacaatg caggtcgaat
    10801 gactccaagc actctttaag agataacgtt catatatctc ccgataagaa taacgcccag
    10861 catctatgaa aataggttgg ccttgatact gtaagcaaaa actattctcg tcactatggc
    10921 tatgggcact tcctagcgga ccatttttga aaaatagata acgatgttca tccttaatgc
    10981 agacatgtcc agagtcttca aagatcatgg acttaggctg ccaagctctc ctttcaaatt
    11041 cctgcagtcg cttgaccttt tctcgcccca ggaacaagag gctaagcaaa tcgactttaa
    11101 catccagacc gttaagaagg tcttccttgt tcaaaaccac agcagacaga ctcaaaattt
    11161 ctgtcgtttc tgtagaatcg ctatcaccaa aagccaaagt tcgtccatct aagcctgtca
    11221 tcatttgaat ataggtcgcc atcttttcca gcaactctcg gtaactatct tgcaagtctg
    11281 gaagcaagag acacaaatcc agcaaggctt tataaacctc tacatgatag agaatcgact
    11341 gttcaaactg gcttccatct cctaaaatct gtgtctcaat ttgctgtttc aactcctctg
    11401 aagcaaaatg gtaagcttct tctagatcca tcttatctga aaagaaataa tagatagcaa
    11461 gcatcggaat tgtttgtaaa atcccccagt tactaagggt gtacttggcg cgatagtggc
    11521 ttttcataaa gtcaatctgc ttttctagac tgaccaaaat tttctctagt tctttctcct
    11581 ctagcaagtc aaatttcaag aggagcaaga gtagtttcaa ccaagtaaag gaacgaatac
    11641 ccgtatccaa ggttctagtc atcaaggatt gaggagaaaa ttctctcacc tgctcaatcc
    11701 aatcaaatag aaagaacttg cacttttgaa tatagctctt atctccttct accacatacc
    11761 ctatcataaa ctgcaagaga tattcttgtc gattgagcat ataagcccat tctggatcat
    11821 cttcaaatac ttgatcccat accatcggct ggatttgatg gatttttgaa caaggctcca
    11881 tatcccaagg actatcaaac ataaaacgat tgtccatcaa gcgttcaagg gaacgcttga
    11941 ctttctcata gtcttttgaa tagtgggaca agatataatc acgacattgg tttccatcga
    12001 ttctttcaaa aaattgtctt ctttcttctt tcattatcta ttaccagaaa aagaactact
    12061 taaaaagcag ttcttttgtc tttcccatta cactttcctt ttctacatag atgaccacac
    12121 cttttgcaat ctgcaaggag accaagtcat ctttgataga aatgattttt ccatgaattc
    12181 cagacaataa caacacttca tcaccagatg ttaaagaagc taaatactct tgtcgttgct
    12241 ccatctgttt gcgaagcaac ttttgctgac gaatagaatg aaagcttgac agtaaaaggg
    12301 gactcactgc caagacaatc actattccat aaaacaatgt tgtatccatt aagctataat
    12361 cttaagccag cttccgataa ttccgatgat aactgttaaa ataacgagtt tatatgttgt
    12421 ccatttcttt tctttgatca agtagtaaac taaaagtgta aatagggctg gtagaagagc
    12481 tggagcaacc ttatcaagca ttccctgaat acttacgata ctttgtttag cgtctgcttt
    12541 aacttcccct gcagcaaagg taatcggcac cataatctta acagatgtcg ctgccaaacc
    12601 agcaattacg gttacaccga taatattggc aatacgagaa atcgttgcca tctgctcgct
    12661 tagtttatca atcacagttg ttcctagttt gtatccatac agaccagttg acaatttaat
    12721 cgctgttaaa atcgtattca tcgcaaggaa gaacaagatt ggaccgacaa ccaagccttc
    12781 ttgagcaaac gaagctgcga tggttgagaa caatggagct aaacagaatt gagaaagaga
    12841 atccccaata cctgccaatg gtcccatcaa ggccatcttg atgctacgtg tttcttttgt
    12901 tggtcgacca ttttccaaca ttacaagatg caagctggta ataaaaggca ggaagtgtgg
    12961 gttggtatta tagaattcac agttttcttc caaggcttgg tagaaacctt cctgatcctc
    13021 tccatagtgt tttttcaaag caggatacat cacattggca tatcccaacc cttgatagtt
    13081 actatagtta aatccatttt gacaaaagaa tgcccgcaaa gacgttttaa gataatcacg
    13141 ttttgttaat ttgttagatc cagtcatcgt gtgcttcctc ctctaccaca tgatccgctg
    13201 tttttggctt gttataaaat tcaatcaaag caaagatagt acctacaatt gcaataccaa
    13261 ttgttgggat gtttagataa gctgcacaaa catatcccaa caagacaaag ggaatcaact
    13321 ctttcttagc catcactgac aagatcatcg caaaaccgat agctgggagc attttaccag
    13381 caactgtcaa acctgtaagt aataccggtg gaatgtagtc tacgagtttc aacaaggtat
    13441 ccattgaaag ggcacccaag caacccaagg taaatccaat aaaggcaaac aaccaaattg
    13501 ttgcatttag agtgaactta aatttcttca aattatggtt tttcaagtgc ttcatcgctg
    13561 tttcaggcgc accagcacgt acagtgtagg cgaaagtttg taagaattga atcgccacag
    13621 caatcggagt agagagggca agagccgctt ctggactgac tttaccagca ctagtgatag
    13681 ccatcaaggt accaaagata ccaggtccga ttgggtttgg tggaacagta cctccagcac
    13741 ctacaccgaa tcccatataa gccaattcac caatagctcc cattgcaaga gcagtaggca
    13801 gatcacctag aataattccg acaccaaatg acagaacaat acatctattg gtgtaaattc
    13861 ctaacagcat tccactaaaa cagaaagctg tccataatcc aattaaaatc gcttgaaata
    13921 cattaatcga cataacgatc tcctctttta aatatagtcc ataatgttga cttgaacagc
    13981 tccatcattt cctgttggag ttgttttcgt attaaatgtt acttgatgag tttggctcaa
    14041 ttccttgagg gctgccttgt cctcttcacc caggaagatg gagcgtgtca cttgctcttt
    14101 accaggggca ttgtgaatgt tcccaatatt gatttctttg atagggacac caccttctac
    14161 caaggttaaa gcgtccttta catcctttac aacgataaag atcgtttgag caggattagc
    14221 cttgtgaatg atatcaatca ccttttgcaa agggaagaaa cgcatggcaa ctgagtctgg
    14281 cacaactgtt ttcatcagag tttgttgcat cttgtccgtg cttacttcgt cattggcaac
    14341 aatgaccgta ttacaaccta ggtattttac ccaaagttgt ccttgtccat gaatcaaccg
    14401 ttcatcgata cgggtcataa taatatttgg cattgtcata tttctcctcc taccaatata
    14461 ggttccagtc tttgtagaaa cggataaggg cttctaggta atagtagtca ccccagatat
    14521 tgccttcatc cactccttta cctgaatgcc atgagtacac accgtggagg agacttgtcc
    14581 caccaggggt aaattgatca tttgcataat gttcgatcaa ggaacgaagc atggcatgca
    14641 tagcatgttt ataaatatct ttgtcagcat ccacctctgg gagatgtttt agcatttcat
    14701 gaatcccaca gacggcgata gctgttgctg aagaatctcg tgattgatca ctaccatcat
    14761 taaaaatcaa atcccaatag gacacatgat cttttggcag acgattcaag aaataattgg
    14821 tcacaccctt aaacaagtca aagcaggact cgtcttttaa gtgacgataa gtcaaaggaa
    14881 taccatagac tccccatgat tgaccacgtg cccagcatga atcatcacta tacccttgtc
    14941 tcgttacacc tttaaagggt tgacctgtct caggatcaaa atagaaggtg tggaaggacg
    15001 aagcgtcatc acggattaca ttattagctg aagcatagaa atgactttct gcaatatcgt
    15061 agtatttttg atcacctgtt tcttgataag caaagaataa gagttggata ttgagcaagc
    15121 agtcgataat caaacggtaa tgctctttct tgcccaagtc tccccaagct tgaataaaac
    15181 cacctttttc ttgatagcgt tcaatcaact tatctgcagc tttcaaggtt gcttctctag
    15241 cctctccatc tccatttatc ttatattcag ccatacaaga cggtgtgtac aagaagccga
    15301 gatcatggtg atccaattct actctcttat tgacacgatc caggaaagaa agaacatttt
    15361 tatgagcgat gtttttaaat gcatcctgtt gactgtattc ataagccaac cacagttctc
    15421 ctgtccagaa accattggtc cattccgtgt tatccatgat tggatagaca ttatcaaagg
    15481 tagctggcgt cgggaaatct tccttgaaat agtcaaggtt gagttctaac tgccgaataa
    15541 ccttatcgat tgcctggccg acttcttctt tcgtcagaag tggtacttct aagaagcgct
    15601 caggcgattt tattttttca atcgtaacct tttttatcat tcttttaccc tttaaatacc
    15661 cgattcgaaa tcttcttcct cttcctctgc atccgttgaa aacaattctt taccatttac
    15721 gactccgccc tgggccgcca ctactgattt attaacaacc tcatcaaagc tatgagccat
    15781 tctagcaaag actgcttcca ttaacatggc taagttcaaa cccgagagaa cattcattgt
    15841 tttggctgga ttttctccca ttatggtaga agaaaccttg aatggcgatc ctcccaagag
    15901 atcacttagg attaaaactt cttcttcatt tgaaattgca agtaagattt tttgcttgag
    15961 ttcatctgct gacattcctt ccacaaagtc aatcgcctcc acattttctt gattgcctgc
    16021 aatcaattgt aaagaactat aaatccctgt agcaaaatgt ccatgcccta caagtacaat
    16081 tttcatcttt tctcctttct tgtttaggtt taccggttta ctttatattc cccattgtaa
    16141 tcctttattt ttatcttgtc aatagttttt ttaaaaaaaa tattagcgct ttcattatct
    16201 ttttaaccat tttaataggc agaaatttca aaatcttccg tttttttagg aaaacaaacc
    16261 tttttataaa ta
//
LOCUS       DAVKEV010000047        15478 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVKEV010000047 DAVKEV010000000
VERSION     DAVKEV010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15478
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.047"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(526..1722)
                     /gene="tuf"
                     /locus_tag="VWZ68_001726"
     CDS             complement(526..1722)
                     /gene="tuf"
                     /locus_tag="VWZ68_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU9372718.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2633..3502)
                     /locus_tag="VWZ68_001727"
     CDS             complement(2633..3502)
                     /locus_tag="VWZ68_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU9372719.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3726..4334)
                     /locus_tag="VWZ68_001728"
     CDS             complement(3726..4334)
                     /locus_tag="VWZ68_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU9372720.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPEKPIPQPNPEHPSVPTPNPELPNQETPTPDKPTPEPGTPKTETPVNPDPEVPTYE
                     TGKREELPNTGTEANATLASAGIMTLLAGLGLGFFKKKEDEK"
     gene            complement(4292..5398)
                     /locus_tag="VWZ68_001729"
     CDS             complement(4292..5398)
                     /locus_tag="VWZ68_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEU9372721.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGRQEKLVESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5509..5763)
                     /locus_tag="VWZ68_001730"
     CDS             complement(5509..5763)
                     /locus_tag="VWZ68_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372722.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(6103..6549)
                     /locus_tag="VWZ68_001731"
     CDS             complement(6103..6549)
                     /locus_tag="VWZ68_001731"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9372723.1"
                     /translation="MDETGIDRYLYRPYAGAPRGEKVYEKISGRRFERISIVAGQVDG
                     EFIAPMIYKKSMTSDFFVEWFKTQLLPALKTPHVIVMGNAGFHPKNILDELCIQDKHF
                     FLPLPPYSPDLNPIEQAWAILKKKVTDLLREVPTIFECLECFFKTR"
     gene            complement(6622..6947)
                     /locus_tag="VWZ68_001732"
                     /pseudo
     CDS             complement(6622..6947)
                     /locus_tag="VWZ68_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331855.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7181..8899
                     /locus_tag="VWZ68_001733"
     CDS             7181..8899
                     /locus_tag="VWZ68_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU9372724.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            9010..9357
                     /locus_tag="VWZ68_001734"
     CDS             9010..9357
                     /locus_tag="VWZ68_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU9372725.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFVGL"
     gene            complement(9636..10472)
                     /locus_tag="VWZ68_001735"
     CDS             complement(9636..10472)
                     /locus_tag="VWZ68_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9372726.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10485..11114)
                     /locus_tag="VWZ68_001736"
     CDS             complement(10485..11114)
                     /locus_tag="VWZ68_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9372727.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11124..11765)
                     /locus_tag="VWZ68_001737"
     CDS             complement(11124..11765)
                     /locus_tag="VWZ68_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9372728.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(11911..13140)
                     /locus_tag="VWZ68_001738"
     CDS             complement(11911..13140)
                     /locus_tag="VWZ68_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEU9372729.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13130..14296)
                     /locus_tag="VWZ68_001739"
     CDS             complement(13130..14296)
                     /locus_tag="VWZ68_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU9372730.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFIAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14440..15453
                     /locus_tag="VWZ68_001740"
     CDS             14440..15453
                     /locus_tag="VWZ68_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEU9372731.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKITYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
BASE COUNT         4637 a         3274 c         2790 g         4777 t
ORIGIN      
        1 cgatttgact gtcctaatcg atttgtcctg ttcttgtttc attttactat agaacgattt
       61 gaaggcgttt atgatattta gctgtacgag agtcttttaa aagtgttttg atggtttgga
      121 tttcttcttt agttgatttc atattactat tgtataatgc tttttgattt gagtctagta
      181 ttatactctt cgaaaatctc ttcaaaccgc gtcagcttcg ccttgtcgta tagatgttac
      241 tgacttcgtc agttctatct acaacctaaa aacagtgttt tgagcagtct gcagctaact
      301 ttctataaca aaatgaaata agaacaagac aaatcaatca agacaatcaa atcgatttct
      361 aagaatgttt tagaagtaga tgtgtactat tctagtttca atatattata gtttgctctt
      421 tgattttcat ttagtattag ttcaatatct aaaaaaagaa ccttgccaag caagattctt
      481 ttagtgtctg acttaaataa ttgttcttct gggaactaaa tcgaattaag cttcgatttc
      541 tgtaaccata cctgaaccaa cagtacgtcc accctcacgg atagagaatg tagtaccttg
      601 ttctacggcg attgggtgaa tcaactcaac atcgattgtc acgttatcac caggcattac
      661 catttcagta cctgctggaa gttcgattga acctgtaacg tcagtagtac ggaagtagaa
      721 ttgtggacgg tagttgttga agaatggagt gtgacgtcca ccttcttctt tagtaaggat
      781 gtagacttca cctttgaatt tagtgtgtgg gttgattgaa cctggtttag cgataacttg
      841 tccacgttcg atttcatcac gttgaacacc acgaagaagg acacctacgt tatctccagc
      901 aagaccttcg tcaagttgtt tacggaacat ttcaacacca gtaacaactg ctttttgagt
      961 ttcttctttg ataccaacga tttcgatttc gtcgttgact ttaacgatac cacggtcgat
     1021 acgtcctgaa gcaactgtac cacgtccagt gattgagaat acgtcctcga ctggaagaag
     1081 caatggtttg tcagtgtcac gttctggttc tgggatatac tcatcaactg tgttcatcaa
     1141 ttccataacg atgtcttcgt atttagagtc accttcaaga gctttaagtg ctgaaccttg
     1201 gataactgga agatcgtcac ctgggaagtc gtattctgac aataggtcac ggatttccat
     1261 ttcaaccaat tcaagcaatt cttcgtcgtc aaccaagtca actttgttca tgaagacgat
     1321 aaggtgttta acaccaacct gacgtgaaag aaggatgtgc tcacgagttt gtggcattgg
     1381 tccgtcagtt gaagctacta caaggatagc tccgtccatt tgagcagcac cagtgatcat
     1441 gtttttaacg tagtccgcgt gtcctggagc gtcgatgtga gcgtagtgac gtttttcagt
     1501 ttcgtactca acgtgcgcag tgttgatagt gataccgcgt tcgcgttctt ctggagcagc
     1561 atcgatagac gcatagtctt taggttggtt aactgatgaa ggcaagcgac gtgccaaaac
     1621 agttgtgata gctgcagtta gggtagtttt accgtggtca acgtgtccga tagtaccaat
     1681 gttaacgtgt ggtttactac gatcgtattt ttcttttgcc atttgagtaa aagcctccaa
     1741 taaaatatat tttatagata gacagtaggc aatacagtct aactttcctt actattttat
     1801 caaatttcag ctaaattgca agtgttttac aacgtttttg tgaattattc ttggtaaaaa
     1861 tttaactaac taatagaaag tactaaatag acttatcctt caaggagttt tcagcattat
     1921 ccatccactc acttgctgaa aatgtaaaca gtctctggtt tatatagtaa aatgaaacaa
     1981 gaatagggca aatcgatcag gacagtcaaa tcgatttcta acaatgtttt agaagttaag
     2041 gtgtactatt ctagtttcaa tctactatac aacctcaaaa ctgtgttttg aacaacctgc
     2101 ggctagcttc ttagtttgcc ctttgatttt cattgagtat aaaattgcag ataaaacgat
     2161 aacaatcata ggactcagca gagtcaatgt aggtcgaaga atagcccccc taatcgctta
     2221 ttttatagca aaatgaaata gaaactgaac attttgttga ggaaggtaaa tcaattcctc
     2281 acaatgtttg agaaagaagg gaggactatt ccaacttcaa cccactataa agcagactta
     2341 caagataggg aacccatctc cgataatata tagtagaatg aaaactgcac aatttgattg
     2401 gagaattcaa accaatttct aacaatgttt tagaaacaag ggtctattat ttcaactgca
     2461 acctactata gcccattgaa gctggaatag cccactgaga cttctaaacc actgctggag
     2521 aggagtttgt ttagagtttc tttcatttcc ctaaaaaatc aaaaagagag aaccagtctg
     2581 atcctctctt acttatagat ggtgctcact caaatgttaa aggagctatt tcttagagat
     2641 aaaggaattt gaatacagct actgccgcaa ttgctgctgc gataggtgct actactggta
     2701 cccaagaata ccaccatttt gaatcgcctt tatgctcacc aagaactgat tttggaagga
     2761 aagcatgaag gagacgtggt cccaagtcac gggctgggtt caaggcaggt cctgtaggtc
     2821 ctccaagtga tgttaccaaa gccataacga ggaatccaag tgccaagtga gccacagaaa
     2881 gtcctgaagc agtgtgtgga gccacctgtg ctttaatagc caagtcagaa aaatcaactg
     2941 tttgtcctgc ttctattgcc ttttgtttca tgaattgaag cacttcagca ccaaagaagt
     3001 ttttagtcaa accaagagct gcaaagaaca aaacaaatga accaacaaac tcattaatca
     3061 aaccattgac agttgctgca tagcgacttt cttttgtacc atggtcaata cttgaaatag
     3121 ttgagaaagt tcccaagatg ttatttgggt tttcagtttt caagtagaat ggacggtatg
     3181 ttgccacaac taaggcttgg ccaaagatag cccccaagac ttgcgcgata atgtaaggta
     3241 ccacttgtgc ccaagggaaa agaccgctaa ctgcaagccc tagagtgaaa gcagggttga
     3301 tgtgattccc agatacgtta ccaaacatca aggctgggat cataaccccc ataccataac
     3361 caacagcgat gacgatccag ccactttggt gacctttcgt acctttaagt tcaacgttgg
     3421 caactgcacc attcccaaga atgatcaaaa tggcagttcc caaaaattca gtggcatact
     3481 tcagtgccca tgtgaaatcc atttgctaga ttctccttaa aattttttag atattcctta
     3541 ttttatcaat ttttacccta tttagcaact gatttctgga aatattttta aaaaaatagg
     3601 attcatagtt tcccagttca acagacttgt aagcgttttt attctttacg aaagacctcg
     3661 ttctcaaaac caggaaaaaa gcccacatct gtgagctttt cctggttcct agattctaaa
     3721 atctattatt tttcatcttc ttttttcttg aaaaatccta atcctagacc agctaacaag
     3781 gtcatgatac cagcactagc caaggtagca ttagcttctg tacctgtgtt tggcaattcc
     3841 tctctcttac ctgtctcata agtcggaact tctgggtctg gattcactgg agtttcagtt
     3901 tttggagtac ctggttctgg agttggttta tctggtgttg gagtctcttg atttggtagt
     3961 tctgggtttg gtgtcggaac acttggatgc tctggatttg gttgtgggat tggtttttct
     4021 ggtgttgata aacggtcata ccttaccgtt atttctttat cactagagtc tgacgtaact
     4081 tcttgtgatt caactgttgg aatatctgga tctttgtact tgtcaatctt accagatata
     4141 acctcgtccc agtttcctgt tgtccattca ccgtaggtta caactcccgt gaccttgttc
     4201 tcagtttttg tacggcttaa ggttacaggt tgaacaacat cttcttttac attttggttc
     4261 gtaactttat caacgtaatg aatgatacgc gttatagtct tcgtctcagt agaggttgct
     4321 gttttgggaa ccactgtttc ctcaacattc tcacggtagt aatagtcaac tgttgcaccg
     4381 tcttctggta cgcatttgca ggagttgcta ccaaggtgta tgttgttttc cttgtgataa
     4441 ctcggtcttc tttgtcctca gttgttgttt tcccttcaat agtttttgat tctgtggtat
     4501 actcagaacc tatcgctaaa tcagctttta taacagactc taccaacttc tcttgcctac
     4561 cttctttata gtaattggct gttactgtag cagtggttgg cgcttcgctt tctctataaa
     4621 ctaaggtcac tgttctacct tcgcttacaa tattcccagt taaacttgca gaatttgtat
     4681 ctgcttcttt aaaagtataa tattttccgt cagtagtagt catgctactg agttttttat
     4741 ctgtgacatt gtagctggta ccaatcagtt gttttttatt ggtaatgtag gttccgtcac
     4801 tttctttttc tccaattcca gtatcatttt tcaatgatag caaacgccct tgttcatcaa
     4861 catagcgaac tttcacattt tctgagatta gttctgccaa ttctgaggtt tttttctttt
     4921 tcttgatttc ttcggttatt ttccctttct cttcttcggg aatatttagt tttggaatga
     4981 ttttttcaac aacggttcgt gatggttcca cagtatcttg gatgactgaa aagtcagcta
     5041 gaattgggag attatactga acacggtgac tttgagtgtt tactcctact ctttcattat
     5101 tctctgaaaa tacttgtacg gtataagaaa caacatcttt tcctaataga acatccccag
     5161 tagagaaata gccgcctttt cctagtttgc tatctccaga gcccacttct ttcctaatct
     5221 tatcagatag ttttttacca gtcagtacat tcgttcgcac aatccctttg tctaccccta
     5281 caaagtggga gaactttttg aactcttcag aaccagatct agcccaacca ttattaaggg
     5341 catttgcttt tgtatttgta ttctctctca aaagtttggc gattagaatt atattcatcg
     5401 gcacttagag ttgctgctat atctgactct tgaataccaa cttccttact accatttcta
     5461 gcggcagtat atgtgtattt atctgtttct acttctagct gattatcctt aacatgatag
     5521 gtaattttct cctggtataa gagtcttcag tagtttatat gctctgtcat catctttagc
     5581 tttagaagca gctgagttta gccaagttgg ggtattagga gtatctttat cagcctgttt
     5641 caagacatta ttcaagtcat ttgctagcct attggttgtc ctcactgtga aagttttctt
     5701 ccagtctgaa ccacttttat tagacttaga tatgctcatg aaatcctggt caacattcaa
     5761 cacaatatcg ccttgttttt tagcatcttc cgttgcttct gcttcaaatt gatcatggag
     5821 tttttgttgc tctggtgtat agttttttta tttacacgat ttaatgtact attttttatt
     5881 ttagtattaa gaactccatt aatacgattt ttaaactctg cttcaaaaaa tcccttaatt
     5941 tgttggtgcg caagttcaac attcaaacct tttttataca agtcttcatt ctgaacgatt
     6001 tcggctacac ggtgaatggt ttgattgtat accgtcttct cttaaccagc agtatcctta
     6061 gttttaatga ctactcgata ggttccttta gaaccgttat agtcatctag ttttaaaaaa
     6121 gcattccaaa cattcaaaaa tagttggaac ttcccttaat aaatccgtca ctttcttttt
     6181 caagatagcc caagcttgct caataggatt caaatccggt gaataaggtg gtagaggtaa
     6241 gaaaaagtgt ttatcttgga tgcagagttc atccaaaatg ttcttgggat gaaaaccagc
     6301 attgcccatg acaataacat gaggtgtctt caaagcaggt aggagttgcg ttttgaacca
     6361 ctccacaaag aaatcgcttg tcatgctttt cttgtaaatc atgggagcta taaactctcc
     6421 gtctacttgt cctgcaacaa ttgaaattcg ctcaaaacga cgtccgctaa tcttttcata
     6481 gactttctcc cctctaggag cccctgcata aggacgatag agatagcggt cgattcctgt
     6541 ttcatcaata taaacaggtg ctaggtgctt taaactatta aaattcttaa gaaataaggc
     6601 tacttttctg ggtcttgttc cttaaagctc gtcatctttt tttaaagtga ccttaatctg
     6661 ctttaaagct gcccatactg aaggaacagc acaatcaaaa tgtgccgcaa tttcccgtaa
     6721 aaaagcatct ggatgagcct ctacaaaggc tttcaattcc tctaaaggaa tctttcggtt
     6781 tttgacgact cgctttttcc tctctatgtg ttcttgttca cgtctttctt ttcccacgtg
     6841 aagagagttc tgacgccaac accaaaaaac ttggctgcct cgacatggct gtgcccctct
     6901 ttgatgtaat ctaatgctcg ctgtttaaaa tcagtactat atgccatagc tttattataa
     6961 tatgcttgtt taaaactaag taactatatc aatgttttgt tatgagaaga cttacttttt
     7021 ttactgaaat tgaatttttc ctagcctaaa catcatataa ccccaaaatt caatctgacc
     7081 tggtttgaag agattttcga agcagataag gttttactaa aactaaaaaa aatgatataa
     7141 tcaaactgat taaatgtttt aaaaataaag gagaatttga atgtcttacc aagaaaatta
     7201 ccagaaatgg gttgattttg tggagcttcc tgactacctt cgtcaagatt tggaaaatat
     7261 ggacgaaaaa actaaggaag atgccttcta tacaaatctt gaatttggta ctgcaggtat
     7321 gcgtggcttg gttggtgctg gtacaaaccg tatcaacatc tacgttgttc gccaagctac
     7381 tgaaggattg gctcgtttga ttgagtcaaa aggtggaaac gagaaagaac gcggtgtagc
     7441 aattgcctac gatagccgtc acttctcacc tgagtttgcc tttgaatctg cggcagttct
     7501 tgctaaacac ggcatcaaat cttacgtatt tgaaagcctt cgtccaactc cagaactatc
     7561 atttgcagtt cgtcatctca actgtttcgc aggtatcatg gtcacagcca gccacaaccc
     7621 tgctccattt aacggttaca aggtttacgg tgaagacggt ggacaaatgc ctccacacga
     7681 tgcggacgct ttgactactt atatccgtgc aatcgaaaac ccatttgcag ttgaagttgc
     7741 tgatgtggaa actgaaaaag cttctggctt gattgaagtt atcggcgaag ctgttgacat
     7801 agaatacctt aaagaggtta aggacataaa catcaaccca gccttgattg aagaatttgg
     7861 taaagacatg aagattgtct acacaccact tcatggtact ggtgaaatgt tggctcgtcg
     7921 tgctcttgcc caagcaggat ttgactctgt tcaagttgtt gaagcgcaag caactgctga
     7981 cccagacttc tcaactgtaa catctccaaa cccagaaagc caagcagcct ttgcccttgc
     8041 tgaagaactt ggtcgtcaag ttggtgcaga tgttcttgtc gcaactgacc cagacgctga
     8101 ccgtgttggt gttgaagttc ttcaaaaaga tggcagctac ctcaaccttt caggtaacca
     8161 aatcggtgct atcatggcta aatacatctt ggaagctcac aaaaacgctg gaactcttcc
     8221 tgaaaatgcc gctctctgca aatctatcgt ttcaactgac ttggtaacga agattgctga
     8281 aagctacggc gcaactatgt tcaacgtctt gacaggtttc aaatttatcg ctgaaaaaat
     8341 ccaagaattc gaagaaaaac acaaccacac ttacatgatg ggatttgaag aaagcttcgg
     8401 ttacttgatt aaaccatttg tacgtgataa agatgccatc caagccgttc ttgtagttgc
     8461 tgaacttgct gcctactacc gttctcgtgg tttgacactt gctgacggta tcgaagaaat
     8521 ctataaagaa tatggctact acgcagaaaa aacaatctct gttactcttt caggtgtcga
     8581 tggtgctgaa caaatcaaag cgattatggc taaattccgc aacaatgctc caacagaatg
     8641 gaacgcaaca gctatcactg tcgtagaaga cttcaaggca caaactgcta ctgttgctga
     8701 cggtactgtt acaaacttga caactcctcc aagtgatgtg ttgaaataca cacttgctga
     8761 cggttcatgg attgccgttc gcccttcagg tacagaacca aaaatcaagt tctacattgc
     8821 agttgtaggg gaaaccaacg aagaatcaca agctaagatt actaacatcg aagcagaaat
     8881 caatgcattt gtaaaataaa gacctataaa agatgagacc aaccaacctc atcttttttc
     8941 gtatcaaatc taagcaattt tagaaacttt atggcatact agacttatca atgaaagcga
     9001 ggtaatctca tggaacaatt tttagataac atcaaagacc ttgaagtcac tacagttgtg
     9061 cgtgcgcaag aagctcttga taaaaaagaa actgcaacct tctttatcgg tcgcaaaact
     9121 tgcccttact gccgtaaatt tgcaggtaca ttgtcaggtg tcgtagctga aaccaaagct
     9181 cacatttact tcatcaatag tgaagaacca agccaactca atgatttgca agcattccgc
     9241 tcacgttatg gaatcccaac tgtaccaggt tttgttcata ttacagatgg acaaatcaac
     9301 gtccgttgcg actcttcaat gtcagcacaa gaaatcaaag atttcgtagg attgtaaaaa
     9361 atcagctaac aagtcttaaa atcacaaaaa cgcataatgt aaggtgcaaa aaccttgata
     9421 ttatgcgttt tattgttcct aaaacagtta catcagtatt tcattacaga acattttaat
     9481 tttggaagtc aaatcaattt ttaacaatgt tttagaaatc acagtgggct attccatatt
     9541 caattatcca gattcaatcg ctattatcgt tttcctagat tacaaaaaaa actacgtttt
     9601 gctaatcaaa acgtagtctc agccactatt ttatcttact gtccttcttt tacttctttg
     9661 gttgctacat cttctccaaa ccatttttgg ctgatttctt ggaacttgcc gtccttgtaa
     9721 agactagaaa aagcttcatt tatcttctta accaaggttg tatcttcctt acgggctcca
     9781 accgcaaaag cttctgtttc tagtccaact gtaaagacat tataatcgtt taaaacacct
     9841 tctgcttcta aataatagtt tgcatagaca cggtcaatca atagaccatc aattcgatcg
     9901 tttttcaaat caatcaaggc ttcattaaag gtttggtatt gattcgcttc cttattagcg
     9961 acaatattct tcaaaagttc tggatttgct tcaaagtccg cataaccaga tgaaccagct
    10021 tgagctccta atgtctttcc agtcatatcc tttgcagtcg tgataccaga tgatttcttc
    10081 gtaaccaata cctgctcatt cttcatatat gagttactga aagccacctt ttcacggcgt
    10141 tcgtctgtag cggaatagcc attccaaatc agatcaatcg ttccttttgt caattcagct
    10201 tctttcaaat cccaatcaat cggttgccaa tttaccgtga ttccgtattt ttcaaaaaca
    10261 gctgtagcta aatcaatatc aaatcctgca taagaaccat ctttctgagc aaatcccatt
    10321 ggaacaaaag tactatcaaa tccaatagta atagacttgt tagactggta ctttgaccaa
    10381 ttatctccac tagtttcgct agaatttttc ccacaagcta ctaagaacaa agcagtcatc
    10441 agactgacta atacaagcat ccattttttc atccattttt cctcctattt aggttctact
    10501 ttcaataata catctgcgat attttcagca aactgcaaat catgggtaac cacaatctgg
    10561 gtcatcccaa gttccctatt ttgcaagatt agcttctcca cttccaaacg taattctgga
    10621 tccagggcag aagttggttc atcgtagcca atgatttctg ggtcaatcat catagcacgc
    10681 gccaaagcca ctcgctgctt ttgcccacca gatagtgaga aaggataggc ctctgcgtgt
    10741 cctcctagtc ctaactgttc caagagtcca ctcgccttct tctcagcctc ttcctgcttc
    10801 attcccatgg tcttcacagg cgataaagtc aaattttcca gaactgatag atgaggaaat
    10861 agttgaaaat cttggaagac aaatcccagt aggttgcgct tctgcaattc atccagctct
    10921 aaaggttgtc cattataaaa gatttgccct gaatcaatgg tttcaagacc tgcaagcata
    10981 cgtaaaagag ttgtcttacc tccaccagaa ggtccaacga tagccaggat ttgcttttca
    11041 ggaatactta gactgaaatt agacaggatt tgtttgtctc caaagacttt attgatattt
    11101 cgtaattcta acatggcagc ctcctatcta taataactat acttcttctc aacttttttg
    11161 gaaataattg tcacaatccc aatcaaaatc aaataaatgg ctcctgccaa gaacatagga
    11221 accagactag catcgcggtt agcagctgtt cgactagcca agataaggtc tgaaattccg
    11281 agagcataga ccaaagaagt atccttgacc aaactcataa cttcattaaa gacactagga
    11341 agaacgatct tggtcacttg gggcaagata atatagcgca ctctgtcaaa agggctaaac
    11401 ttcaagacct tggcagcctc atactgtcct cttggaatag tgtcaattcc cccacggaaa
    11461 atttctgcaa agtaagccgc ataattcaaa acaaaggcaa taatagctgc aggaaggcgg
    11521 tctaaacgaa tcccaatact tgggagcaca taatagataa aaatcagttg caagagtaag
    11581 ggggttcctc gcataaccca gatgtaaatg ttaatcagat aatggagggg cttccaatgg
    11641 acttgcaagg caaaggcaat caaaacgccc aagggaatcg aaaatagcaa gaccagtgca
    11701 aagacctgta cagtcgtgct cgcaccattc agtaaactcg gtaatatctc aaataaataa
    11761 gacatactgc acctcctaaa agtaattgtt cctattatag catgaataaa caagattacc
    11821 aagtattttt gtaaaaagat tctaccatat acaaataaaa accgtagcta tcaaaagaga
    11881 taaactacag ttctatatgt ttaaacattc ttacaatctc tcaaacagtt cttgcatttg
    11941 cacatcatct ggaaccagtt ttaagtaagt gtgagcatgg acttttgctt cttcaaaatg
    12001 tcccaattca cgcaagagat agatatagtg ttccagaaat tctggattgt ccttcaaatc
    12061 tcctgtcaac tcttgataat gctcataagc agtatccaaa tcgtccattt cttgataaga
    12121 acgagcaatc atccacttgg tcaaaagatt ttctggctcc tcactctgca agtctagaat
    12181 atcctcataa cgctcctgct ccagataaat agtggctaaa cgaagcaaga tttcttctgt
    12241 atcctcagcg tcttcttttg cagtaaggag ataattttct gcaccactag catcatgcaa
    12301 ttcataagaa aattgtgaag cagctagcaa gaggcgagtt tcaaagggat ttttctctaa
    12361 tccttgctta gcgatacgca gggcttcttg aacttgatgt tccttatgta aagcctgact
    12421 gtacccatac tcatagcctt caaagtcagg agaaatggta tcaagctgct taaagtagag
    12481 ggtggctttt tgatattctt cttgatcaaa ataaagactg gccaactcaa aagctgttaa
    12541 gtcatcgtat tctaactcca gggctttttc taaaaactca gtagccgttt caaatttccc
    12601 taactgagca taggcaaagc caattcgttg ataggtggaa atgcccgttt gctcataaat
    12661 cgagcgatta tctaactggg cataggcttg aatagccgct tggtaatttt ccaactcact
    12721 atccaactct gccaaaccca atatcaagag agaatcctct gagtaggtca aggcctccaa
    12781 taatttctca cgtgccacat ctgtcaaacc ttccagctgg taaaggtctg ccttcagagc
    12841 caaagacgag acataccagt cactgtcagc ttggatttcc tcaagatagg taaaggcttc
    12901 ttctatttga ccatcctcgc tagcaattgc agctagatta agatgaacct ctggaaaatc
    12961 ctctacaatt ttcaggtaaa tttccttggc ctgaggatag aaaccaatcc cttcaagata
    13021 agttgccaac tcatacagaa gatcacttga atcattttct aaagctttgg cgaaataatg
    13081 ctcagcctta gttaaatctt gctcctccaa agcctgtaac atctgttgac tattgttcac
    13141 tcttgacttc ctcaccctct aattcatata gaccactgac taccttatac cattcgaaaa
    13201 tggctgaaat gacaacctta gcagaggcat aaaccggaat accaagtaaa actccccaga
    13261 taccaaacat agatcctgaa gttaacaaaa caaagagaac attaatagga tggatgttta
    13321 attgacttcc caaaatcaat ggagagacaa aacggccttc aatagtttgt tctacaataa
    13381 agacaatcac tactttcaaa agcatgactg gaccagcaat caaacccaat actagggcag
    13441 gaagcatggc tagaaagcta ccaagataag ggaccagatt taaaatacca gcagtaaccc
    13501 ccagcgtaac cgcatagcgt agaccaataa tcttgaagaa gatgataaac attactgcta
    13561 caataatagc cactgtcact tgccctcgaa catagttgga caactgttga ttcacatctg
    13621 atagaacttg tccaacaggt tccttcaatt ttcttggaat gaattgggtc aaatagttac
    13681 gcaagccttt cccatcacgc aagagataaa agagcatgaa aggaacgata atcaaggcaa
    13741 caatcacttg agaagctccg ctaataaagg cactcaccca gttgactgcc tgagatgaaa
    13801 ccttacttgc caaaactgta gcctggctag aaaaattggt caaaacttgc tctaattgag
    13861 gtctgaaatc atctggcagg tgctgggcta ccaatccatt aacaatccta tctatatctt
    13921 ctaagtaaac aggaacgttt cttgcaaagg tcaaaacctg acgttgcaga tttggaatgg
    13981 cgactgccaa gccccaaatg ataaagagag cgatgataac aaagacaata gtgatagcta
    14041 taacacgatt aaccttatgc ttctccatcc aatcaacaat aggattcaac aaataatata
    14101 acaaaccaga caaaatgact ggcaacatca caactgctat aaagtctaaa acaggtgaaa
    14161 atagaaaact aatcttactt aaaataaaaa gattcaatcc caataataag gttactaaaa
    14221 ataccgtaat tgccttgtta tctaaaaacc acttgaaaaa ccaagatagg ctaaaatgtt
    14281 tctctttttg ctccataaat acttcctttc tattgttctc tcattatacc atttttgaaa
    14341 caaaataact cttttttaaa gtgcttacat ctaattgaat gtctttaatt tgcttgtttt
    14401 tgtgatataa tagtcttatc tttacacaga ggtatagtaa tgaaagaaac tgtttatttt
    14461 ggaacttata cacgtcgtac ttctcaaggg atttacaagg cagactttga tacagaaact
    14521 ggtcagcttt caaatctaga actttttgca gctgagccaa gtccaaccta ccttgccttt
    14581 gaccagcacc aacatttata cactgttggt agccaagacg ataagggggg aattgcagcc
    14641 tatcaaactg acgggactgt gttaaatcat gttgttgaag aaggagctcc ccactgttat
    14701 gttgctgtcg atgaaaagcg tgatttggtt tacgcagcca actatcacaa gggacaagtc
    14761 cttgtttata aacgccagga agatggtagt cttctactta gtgatatgga tcaacacagt
    14821 ggccaaggtc cacatgaaaa tcaagcttcc ccccatgttc actatacaga tttaacacct
    14881 gaccactatc tagtgacctg cgacttggga actgaccaag tcatcaccta tgacctcgat
    14941 caagaaggaa aattatctaa gctctatacc tatcacagca agccaggagc aggctcacgc
    15001 catatcattt tccataacca ctataaaatc acttatctca tttgtgaact caatagtact
    15061 atcgaagttt taatctacga tggcgttggc gaatttgaac gtatgcaggt tatttcaact
    15121 ttaccagaag cttacgaagg ctttaatgga accgctgcta ttcatctctc taaagacggt
    15181 aaatacctct acgcttctaa ccgtggccat gattctatcg cagtatatac catccttgcg
    15241 gacggtagct tagagttatt agaaatcgtt ccaacgcatg gtcagactcc acgtgatttt
    15301 gatttgacac ccgaccaaaa atttctcatt gttgtccatc aagactctga caatgcaact
    15361 gtctttaaac gtaattgtga caatggtcgt ctagcagaac tctccaacga cttccatgtt
    15421 cccgaagcag tctgcatccg ttttgctcct taaaacacca taaaaaatga acttggta
//
LOCUS       DAVKEV010000048        12295 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVKEV010000048 DAVKEV010000000
VERSION     DAVKEV010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12295
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.048"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            408..3683
                     /gene="rexB"
                     /locus_tag="VWZ68_001741"
     CDS             408..3683
                     /gene="rexB"
                     /locus_tag="VWZ68_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEU9372732.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMNFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGAEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYIDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERKNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3680..7330
                     /gene="addA"
                     /locus_tag="VWZ68_001742"
     CDS             3680..7330
                     /gene="addA"
                     /locus_tag="VWZ68_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEU9372733.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGCQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFCFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKPHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     HVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7545..8723
                     /locus_tag="VWZ68_001743"
     CDS             7545..8723
                     /locus_tag="VWZ68_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372734.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSIC
                     VCGNVIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKNGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDYRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            8932..>12295
                     /locus_tag="VWZ68_001744"
     CDS             8932..>12295
                     /locus_tag="VWZ68_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU9372735.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIEIKIDFQEEI
                     QENPDLVEGIVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSKAVITDKG
                     ETEVQPESPDTVVSDKGEPAVQPELPEAVVTDKGETEVQPESPDTVVSDKGEPKQVAP
                     LPEYTGPQASAIVEPEQVAPLPEYTGVQAGSIVEPEKVEAPKEYTGKIEQPSAEDTKP
                     ENGASSTNGESERPKDKIKEEKQVDKKLELRNVSNVELYTVENNKYRHITAVDGALDS
                     SLKYFMKVKSENFKDIMLPVTKIESTTKNNKEVYKIVAHAENLIQHENNVISNDYTYY
                     LPKTQQSETGVYTSFKNLVDAMNSDPNGTFHLGATMDAREVELPDDQESYVKNEFYGK
                     LIGKNNGKYYAIYNLKKPLFKTLNTATIQNLSIKEANVSSKEDAATISKEAKYNTLID
                     NVHSDGIIAGERGIGGLVSKVDNSRISNSSFTGRITNTYDTTAGYEIGGLVGKLSGSL
                     ASIEKSIASIDIASNAKSGDQIVGGIAGVVEKSATIKYSYVEGNVNNVRHFGKVGGVA
                     GNLWDRDSQDVSKSGKLSYVLSDVNVTNGNAIAGYNFNGIKTIETYSNKNNKVVNVVQ
                     EDDEVVTKDSDVQRGTVLDADKVKEKKVELVSKHSTKVEDFDFTSRYNTNYNEVTGYQ
                     QSREQVYKNIEKLLPFYNRETIVKYGNLVEDNSDLFTKKLLSVVPMKNNEVITDINKN
                     KQEINKLLLHFEGNKSRVLNIAYKNDFSKVAEY"
BASE COUNT         4064 a         2351 c         2560 g         3320 t
ORIGIN      
        1 cacggtgtac tattatagtt tcaatttact atagttcaat cattctatca agaatattga
       61 atatataaag gcacgtaata ttaaaacttc ttctgatatc gaattagagt ccgatgttga
      121 tggcgataaa tcagacaatc tacccgtcga cattaagata ctgggacaac acattgaagt
      181 gtattccgta cctaagaaac aatcataaaa ctcaaagcct tgttaccgag gcttttttat
      241 tatgtgattt tcagtagcca gacttattct atctaataca agtaaagcta agtatttaag
      301 atttagcaga tgatgaagaa aagaaaggat ggcctaaata ttttaacaga tttacgaggc
      361 taatcatggt ataatatagg gtgatgaaaa attccaacga ggctgagatg aaattacttt
      421 atactgatat tcgaacttct ttgacagaaa ttctaacaag agaggcagaa gagctagttg
      481 cagctggcaa gcgggtcttc tacattgccc ccaactctct ttcttttgaa aaggaacgcg
      541 ccgtgctgga atgcttgtcc cagcaggctt ctttttcgat taccgtcacg cgctttgctc
      601 aaatggctcg ttatctggtc ttgaatgatt taccagctaa aactactctt gatgatatcg
      661 gtcttgggtt ggccttttac aaatgccttg ccgaactcga tcccaaggac ttgcgtgttt
      721 atggcgctat taagcaggat cctcaattga tccagcagtt aattgagctt taccatgaga
      781 tgaccaaatc tcagatgaat tttttggact tggagaattt aacagatgag gataagaggg
      841 cggatttact cttgattttt gagaaagtaa cagcctatct taatcaaggg cagttagccc
      901 agggaagtca gttgtcccat ttgattgagg ctattgagaa tgacaaggta agtagtgatt
      961 ttaatcaaat cgccttggtc attgacggct ttactcgttt ttctgctgag gaagagcggg
     1021 ttgtggactt acttcacggc aaaggtgctg agattgttat cggggcttat gctagtaaga
     1081 aagcctatac cagtcctttt agcgagggca atctctacca agccagcgta aaatttctcc
     1141 atcatctggc ttctaaatac caaacgcccg ctcaggactg ttctcaaact catgagaaga
     1201 tggatagttt tgacaaggcc tctcgtttgt tggagtcttc ttatgacttt tcagaactcg
     1261 ctttggatgt cgatgagaaa gaccgtgaaa atttacaaat ctggtcttgt ttgacgcaaa
     1321 aggaggagtt ggagctagta gcccgtagca ttcgtcagaa attacatgag aactcagacc
     1381 tgagctacaa gcattttcgt attctcttgg gggatgtagc ttcttaccag ttatctctca
     1441 aaaccatttt tgaccagtat cagattcctt tttatcttgg tagaagcgaa gccatggctc
     1501 atcatccctt gactcagttt gtcgagtcta ttttagcttt aaaacgttac cgttttcgtc
     1561 aggaggattt gattaatctt cttagaactg acttgtatat tgacctcagt cagtctgata
     1621 ttgatgcttt tgaacaatat atccgctatc ttggtattaa tggcttgcca gcctttcagc
     1681 aaaccttcac caaatcccac catggaaaat ttaatcttga gcgtttgaat gtcctccgcc
     1741 tgagaatttt agcacctctt gaaaccctct ttgccagccg aaaacaaaag gctgaaaacc
     1801 tcctacaaaa atggagtgtc tttctaaaag aaggagctgt gaccaagcag ttacaagatt
     1861 tgacaaccac tttggaagct gtagaacagg aaagacaagc cgaagtttgg aaggcttttt
     1921 gccatgtttt agaacaattt gcgactgttt ttgctggttc acaggttagt ctggaagact
     1981 tcctagcctt gctccattct ggaatgagtt tgtcccaata ccgtaccatt ccagcaacag
     2041 tggacactgt tctggtgcag agttacgatt tgattgcacc attgactgct gactttgtct
     2101 atgctattgg actaactcag gacaatttac caaaaatttc tcaaaacacc agtcttctga
     2161 cagatgaaga aaggaaaaac ctaaaccaaa cgaccgaaga aggcgttcaa ttactgattg
     2221 ccagcagtga aaatctcaag aaaaatcgct acactatgct ttccttggtc aattctgctc
     2281 gtaagcagtt gttcttgtcg gctccaagcc tttttaacga aagtgaaagt aaggaatctg
     2341 cctatcttca agagttgatc cattttggat ttaggcggag agagaagagg atgaatcaca
     2401 aaggactgtc taaggaggat atggggtcct atcacagtct tttgtctagt ctggttgcct
     2461 atcaccagca gggtgagatg agcgatactg agcaagattt gacttttgtc aaggttctgt
     2521 cgcgtgtcat aggtaaaaaa ctagatcagc aaggtctgga aaatccagct atcccaacca
     2581 gtccaagcag caagacctta gccaaggaca ccttgcaagc tctctatcct gccaaacagg
     2641 agttttacct gtctacgtcg ggtttgacag agttttatcg caatgaatac agttatttcc
     2701 tacgctacgt tttaggcttg caggaggaat tacgtttgca tcctgatgcc cgtagtcacg
     2761 ggaatttctt gcatcgtatc tttgaacgcg ccttacagtt gcctaatgaa gattcctttg
     2821 accaacgtct agaacaagct attcaagaaa ccagtcaaga acgcgaattt gaagctattt
     2881 atcaagaaag tttggaagcc cagtttacca aggaagtttt gcttgatgtt gcacggacga
     2941 ctggacatat tctccgacac aatccagcca tcgaaaccat caaagaagaa gcaaattttg
     3001 gtggaaaaga ccaagccttt attcaattag acaatggacg cagtgtcttt gtacgaggca
     3061 aggtggaccg gattgaccgt ttgaaagcta atggagcgat aggagtagta gactacaaat
     3121 ccagtctgac tcagttccag tttcctcatt tctttaatgg gctcaattct cagttaccaa
     3181 cctatcttgc tgccctaaaa agagaagggg agcagaactt tttcggcgcc atgtacttgg
     3241 aaatggctga acctgtccaa tctctgatgg cggtaaaaag tctggcagga gcagtggtag
     3301 aagccagcaa atctatgaaa taccaagggc tcttcttgga aaaagaaagc agttatttag
     3361 gcgaatttta taacaaaaac aaggctaatc aactgacaga tgaggaattt cagctcctac
     3421 tggactacaa tgcctatctt tacaagaaag ctgctgagaa gattttagca ggccggttcg
     3481 ccatcaatcc ttatactgaa aatggcagaa gcattgcccc atacgtccag caacatcagg
     3541 ctattacagg ctttgaagcc aattaccatc tgggccaagc ccgtttccta gaaaagttgg
     3601 acctagctga tggcaagcgt ctggtcggag aaaaactcaa gcaagcttgg tttgaaaaaa
     3661 taagagagga gttaaatcga tgaagcttat tcccttttta agtgaggagg agattcaaaa
     3721 actgcaagaa gcagaagcaa attcgagcaa ggaacagaag aaaactgccg aacaaatcga
     3781 agctatctac acttctggtc agaatatcct ggtctcagca tcggctggtt ctggaaagac
     3841 ctttgtcatg gtagagcgca ttctggacca attggcgcgt ggtgtcgaaa tttctcaact
     3901 ctttatctca acctttaccg tcaaggctgc aactgaactt aaagaacgtt tagagaaaaa
     3961 aatcagcaag aaaatccaag aaacagatga tgtcgatctc aaacaacact tgggttgcca
     4021 gttggcagac ctacccaacg ctgccatcgg aaccatggac tctttcacac aaaaattcct
     4081 tggcaaacat ggttatctgc ttgatattgc acctaatttc cgtattttac aaaaccaaag
     4141 cgagcaactt cttctcgaaa acgaagtctt tcatgaggtc tttgaagcgc attaccaagg
     4201 taaacagaaa gagagcttta gtcatttgct gaaaaacttt gctgggcgtg gcaaggacga
     4261 acggggtctg cgccagcaag tctataaaat ctatgacttc ctccaatcca ccagtaatcc
     4321 tcaaaagtgg ctgagtgaat ctttcctcaa aggctttgag aaagctgatt ttaccagtga
     4381 aaaagaaaaa ctgactgagc aaatcaaaca agccctctgg gatttggaaa gctttttccg
     4441 ttaccatctg gataacgatg ccaaggagtt tgcaaaggct gcctatttag aaaatgttca
     4501 gttaattctg gatgaaattg gctccctaaa tcaggagttc gatagtcagg cttatcaggc
     4561 agtacttgcg cgtgttgtcg ccatctctaa ggagaaaaac ggtcgtgctc tgactaatgc
     4621 cagccgtaag gctgatttga agcccctggc tgatgcctac aacgaagaga gaaagaccca
     4681 gtttactaaa ctaggacaat tatcagacca gatagcgatt ctcgactatc aagaacgtta
     4741 tcatggagac acttggaaac tagctaaaac cttccaatct ttcatgagcg attttgtaga
     4801 ggcttatcgt cagagaaaac gacaggaaaa tgcctttgaa ttcgctgata tcagccatta
     4861 caccattgag attttagaaa atttcccaca agttcgtgag tcttatcagg agcgcttcca
     4921 tgaagtcatg gtcgatgagt atcaggatac caaccatatt caagaacgga tgctggaatt
     4981 gttgtctaat ggccacaatc gctttatggt gggagatatc aagcaatcca tctatcgttt
     5041 ccgtcaggca gacccgcaga ttttcaatga gaaattccaa cgctatgcgc aaaatcctca
     5101 agaaggcaag ctcattctcc tcaaggaaaa tttccgtagt agttcagaag tgctgtcagc
     5161 aaccaatgat gtctttgaac gtctcatgga ccaagaggtc ggcgaaatca actatgataa
     5221 catgcaccag cttgtttttg ccaataccaa actgactccc aatccagaca acaaggctga
     5281 atttctcctc tacgacaagg acgatacagg tgaggaagaa gagagtcaaa cagaaacgaa
     5341 actaacaggc gaaatgcgct tagttatcaa ggagattctg aaacttcatc aagaaaaagg
     5401 tgttgccttt aaggaaattg cccttctgac ctccagccgc agtcgtaatg accagattct
     5461 cctcgccctg tctgagtacg ggattcctgt caaaactgac ggagagcaaa acaattatct
     5521 ccaatcccta gaagtgcaag tcatgctaga cactcttcgt gtcattcaca atcccctgca
     5581 agactacgcc ttggttgccc ttatgaagtc tccaatgttt tgttttgatg aggatgagct
     5641 agcacgtttg tcccttcaga aagcagagga taaagtccac gaaaatctct atgagaaact
     5701 ggtcaatgca caaaaaatgg caagtagtca aaaaggcttg attcacacag ctctagctga
     5761 aaaactaaag caattcatgg atatcctagc ttcttggcgc ttgtatgcca aaccccactc
     5821 tctctatgac ttgatttgga agatttacaa cgaccgtttt tattatgact atgttggggc
     5881 tttgccgaat ggtcctgcta ggcaggccaa tctctatgcc ctagcactgc gtgctgatca
     5941 atttgaaaag agcaatttca aaggtttgtc gcgttttatt cgtatgattg accaagtctt
     6001 agaagcccag cacgatttgg caagcgtggc cgtcgcaccg ccaaaagatg cagtagagct
     6061 catgaccatc cacaagagta aagggctgga gtttccttac gtctttatcc tcaatatgga
     6121 tcaagatttc aacaagcaag actctatgtc agaagtcatt ctcagtcgtc agaatggtct
     6181 tggtgtcaaa tatattgcca agatggagac aggggcagta gaagaccact atcctaaaac
     6241 catcaaactc tccattccta gtctgaccta taggcagaac gaagaggaat tacagctagc
     6301 aagctattct gagcagatgc gtttgctgta tgttgctatg acgcgggctg agaaaaagct
     6361 ctatcttgtc ggcaagggtt ctcgtgaaaa gctggaatcc aaggaatacc cagcagccaa
     6421 aaatgggaaa ctaaatagca atactagact gcaagcacgg aatttccaag attggctttg
     6481 ggctatcagt aaagtgttta ctaaggacaa gctcaacttt agttatcgtt ttattggcga
     6541 agatcagttg accagagaag ctatcggaga gttggaaacc aagagtcctc tccaagatag
     6601 ctcccaagca gacaatcgtc agtcagatac catcaaagaa gctctggaaa tgctgaagga
     6661 ggtggaagtt tataatactc ttcaccgcgc agctattgaa cttcctagtg ttcaaacccc
     6721 aagtcaaatc aagaaattct acgaaccagt tatggatatg gaaggtgtcg agattgctgg
     6781 tcaaggtcag tcagtaggca agaaaatcag cttcgatttg ccagattttt caaccaaaga
     6841 aaaggtaact ggagctgaga ttggtagtgc tactcacgaa ctcatgcaga gaattgacct
     6901 cagccagcaa ctaacccttg ctagcctaac agaaacactc aaacacgttc aaactagcca
     6961 agctgtcaga gacaagatca atcttgataa aattcttgct ttctttgaca cagtactcgg
     7021 tcaggaaatt cttgctaata ccgaccatct ctatcgcgag caacctttct ccatgctcaa
     7081 acgagaccaa aagagtcagg aagactttgt tgtccgtggt atccttgatg gctatctgct
     7141 ttacgaaaac aaaattgttc tgttcgacta caagacagac cgctatgatg aaccaagtca
     7201 actcgtagac cgctatcgtg gtcagttagc tctatacgaa gaggctttat cacgagccta
     7261 ttcgattgaa aatattgaaa aatacttgat tttactcggt aaagacgagg ttcaagttgt
     7321 aaaagtataa cttatactct ttgaaaatct cttcaaacca cgtcagcttc gccttgctgt
     7381 atatatggtt actgacttcg tcagttctat ccacaacctc aaaacagtgt tttgagctga
     7441 cttcgtcagt tctatctaca acctcaaaac agtgttttga gctgactgcg gctagctttc
     7501 tagtttgctc tttgattttt attgagtatt agaaaggaga cctcatgaca cttccagtta
     7561 gaaaatccct gcacgatgca gttttacagg cttcgaaagc ggatacttgg gaacaagcta
     7621 ccaaggaatg gaatgaagtt tccttgattt ttaacggtat cggccgtagc atttgtgtct
     7681 gtggaaatgt catcaaatac gcttatgaac tctttaacgg tgtcacaggc caacgcctct
     7741 ttccaattgg tagcgactgt gttcgtcatt ttcatcgatt gtcccttgac cagcaattgg
     7801 aagaggaaga aaaactgctc agaaaggttg aaaatctaac cagaaaagct cagaaaaagg
     7861 aaaaaatcaa ggtcaataaa agtgactttg acgagcgact tctaaaatgg ctctgggaaa
     7921 aaggtgtttt caaacccaat cgtggcaatc aatttgcgcc tgagagagac taccagcttt
     7981 tcctagaagt ctttcaggga ggaagttgga ccaaggcgga accaaagaaa aaggctcgga
     8041 tggaagaagt ccttgaaaag tgtatcaaac cctttttact tgggaaatcg gatgaccaac
     8101 tctaccttgt caagctaggc aaggagaaaa ttgactacga acaagaactc cgtatccagg
     8161 cagagaaaga acgcaagaag agggataaaa tcgccaagca atatgcagac aatctggttc
     8221 tagccatggg acccgcagag cgtgcttatc aagattactt tggctttaca gagaccctga
     8281 ctcaagaaga acgcaagtgg gaaaaaattc tttttggtaa aaatagagca gaacgggcta
     8341 ttaaggccaa acaataccaa aaagagctgg aaaaagacca acgaattgcc agtcaggatc
     8401 caattgaaag aaaacagaaa cagacttggc tcctcaattc ctattttcgt gagcttcctg
     8461 aagaaaaagc tcgattttct aggctcttat tagaatatcg aaaaaatggt gaagtaccct
     8521 tttcaactga atacctgtca gatcatctca tcgacttttt ctataaaatg aaagcctttg
     8581 aatttgaaat cgcaccagaa caagtccgag attttctaaa aaaaagcctg caggaagact
     8641 atcgctcatc agcacaagga agctggatag aaggaattct cctcaactgc ctcaaaccat
     8701 ttttagaacg attagtgata tgagtaacac ctaccgtgta aatttcatgg taggtgttat
     8761 tgtaccccca aataatataa aacaaagtat gaaagcgcat ctcaatttta agactttttt
     8821 gtaaattaag agtataatta aggtatactg ccttttctat agataataga taatacacta
     8881 atataataaa ggtctttgta acatatataa attttatttc aaggaggaat aatggaaaag
     8941 tattttggtg aaaaacaaga gcgtttttca tttagaaaat tatcagtagg acttgtatct
     9001 gcaacgattt caagtttatt ttttatgtct gtattagcta gttcatctgt ggatgctcaa
     9061 gaaactgcgg gagttcacta taaatatgtg gcagattcag agctatcatc agaagaaaag
     9121 aagcagcttg tctatgatat tccgacatac gtggagaatg atgatgaaac ttattatctt
     9181 gtttataagt taaattctca aaatcaactg gcggaattac caaatactgg aagcaagaat
     9241 gagaggcaag ccctagttgc tggtgctagc ttagctgctc tgggaatttt aatttttgct
     9301 gtttccaaga aaaaggttaa gaataaaacg gtattacatt tagtattggt tgcgggaata
     9361 ggaaatggtg tcttagtttc agtccatgct ttagaaaatc atcttttgct aaattacaat
     9421 acggactatg aattgacctc tggagaaaaa ttacctcttc ctaaagagat ttcaggttac
     9481 acttatattg gatatatcaa agagggaaaa acgacttctg attttgaagt aagtaatcaa
     9541 gaaaaatcag cagccactcc tacaaaacaa caaaaggtgg attataatgt tacaccaaat
     9601 tttgtagacc atccatcaac agtacaagct attcaggaac aaacacctgt ttcttcaact
     9661 aagccgacag aagttcaagt agttgaaaaa cctttctcta ctgaattaat caatccaaga
     9721 aaagaagaga aacaatcttc agattctcaa gaacaattag ccgaacataa gaatctagaa
     9781 acgaagaaag aggagaagat ttctccaaaa gaaaagactg gggtaaatac attaaatcca
     9841 caggatgaag ttttatcagg tcaattgaac aaacctgaac tcttatatcg tgaggaaact
     9901 atagagataa aaatagattt tcaagaagaa attcaagaaa atcctgattt agttgaagga
     9961 attgtaagag taaaacaaga aggtaaatta ggtaagaaag ttgaaatcgt cagaatattc
    10021 tctgtaaaca aggaagaagt ttcgcgagaa attgtttcaa cttcaacgac tgcgcctatt
    10081 ccaagaatag tcgaaaaagg tactaaaaaa actcaagtta taaaggaaca acctgagact
    10141 ggtgtagaac ataaggacgt acagtctgga gctattgttg aacccgcaat tcagcctgag
    10201 ttgcccgaag ctgtagtaag tgacaaaggc gtaccagaag ttcaaccagc gttgtccaaa
    10261 gcagttataa ccgacaaagg tgagactgag gttcaaccag agtcgccaga tactgtggta
    10321 agtgataaag gtgaaccagc agtccaacca gagctaccgg aagcggttgt gactgacaaa
    10381 ggtgagactg aggttcaacc agagtcgcca gatactgtgg taagtgataa aggtgaacct
    10441 aaacaggtag caccgcttcc agaatataca ggaccacaag ccagcgctat tgttgaacca
    10501 gagcaggtag caccactacc agaatacaca ggggtacaag ccggatcgat agtcgagcca
    10561 gagaaagtag aagcaccgaa agaatatact ggtaaaatcg aacagcctag tgcagaagat
    10621 actaaacctg aaaatggggc aagctctaca aatggggaat cggaacgtcc taaagataaa
    10681 attaaagaag aaaaacaagt cgacaagaaa ctagaactta gaaatgtttc aaacgtggaa
    10741 ttatatacgg tagaaaataa taaatatcga catattacgg ctgtagatgg tgctttagat
    10801 agttcattga agtatttcat gaaggtaaaa tcagaaaatt ttaaagatat aatgttgcct
    10861 gttactaaaa ttgaaagtac aacaaaaaac aataaagaag tatacaaaat tgtggctcat
    10921 gcagaaaatc taattcaaca cgaaaacaat gttatttcga atgactatac atattattta
    10981 ccaaaaactc agcaaagtga aactggcgtc tatacatcat ttaaaaattt agttgatgca
    11041 atgaatagtg accctaatgg aacattccat ttaggtgcaa ctatggatgc tcgtgaagtt
    11101 gaacttccgg atgatcaaga aagttatgta aaaaatgaat tttacggaaa attaataggt
    11161 aaaaataatg gtaagtatta tgctatttat aacttgaaaa aacctttatt taaaactcta
    11221 aacaccgcta ctattcagaa tctttcaata aaagaagcga atgtttcttc taaagaagat
    11281 gctgctacaa tatcgaaaga agcaaaatac aatactctta tagataatgt tcattctgat
    11341 ggtattatag ctggtgaacg tggaattggt ggattggttt caaaagtaga taactcgaga
    11401 atttctaata gtagttttac aggcagaata actaacacat atgatacaac tgcagggtat
    11461 gaaattggtg gtttagtagg taaactttct ggttcgcttg cttctataga gaaatcaata
    11521 gcatcgattg acatagcctc taatgcaaaa tcaggagatc aaattgttgg tggtatagcc
    11581 ggagttgttg agaaaagtgc gacaattaag tatagctatg ttgaaggaaa tgttaacaat
    11641 gtgcgacact ttggtaaagt tgggggagtt gcaggtaatc tttgggatag agattcacaa
    11701 gatgtaagta aatcaggtaa actatcatat gttttaagtg atgtcaatgt tacgaatggt
    11761 aatgctatag ctggctataa tttcaatgga ataaaaacga ttgaaacata tagcaataaa
    11821 aataataagg tagtaaacgt agtacaagaa gatgatgagg ttgtgactaa agattcagat
    11881 gtacaaagag gtacggtatt agatgctgat aaagtaaaag agaaaaaggt agaattggtt
    11941 tctaaacaca gcactaaagt agaagatttt gattttactt caagatacaa tactaattac
    12001 aatgaagtaa caggttacca acagtcgaga gaacaagtat ataaaaatat tgaaaaatta
    12061 cttcctttct ataacagaga aacaatagtt aagtatggta atttagtaga ggataacagt
    12121 gacttattta ctaaaaaact tctatcagtt gttcctatga agaacaatga agtaataact
    12181 gatattaata aaaataaaca agaaataaac aaattgttat tacattttga aggtaacaaa
    12241 tcacgagtat taaatattgc atataagaat gatttctcta aagttgctga gtatg
//
LOCUS       DAVKEV010000049        12045 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVKEV010000049 DAVKEV010000000
VERSION     DAVKEV010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12045
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.049"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(140..1342)
                     /gene="rpsA"
                     /locus_tag="VWZ68_001745"
     CDS             complement(140..1342)
                     /gene="rpsA"
                     /locus_tag="VWZ68_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEU9372736.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFVDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRVARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1504..1575)
                     /locus_tag="VWZ68_001746"
     tRNA            complement(1504..1575)
                     /locus_tag="VWZ68_001746"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1541..1543),aa:Gln,seq:ttg)
     gene            complement(1585..1665)
                     /locus_tag="VWZ68_001747"
     tRNA            complement(1585..1665)
                     /locus_tag="VWZ68_001747"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1629..1631),aa:Tyr,seq:gta)
     gene            complement(1715..1945)
                     /locus_tag="VWZ68_001748"
     CDS             complement(1715..1945)
                     /locus_tag="VWZ68_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEU9372737.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2113..2757)
                     /gene="pcp"
                     /locus_tag="VWZ68_001749"
     CDS             complement(2113..2757)
                     /gene="pcp"
                     /locus_tag="VWZ68_001749"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU9372738.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2772..3695)
                     /locus_tag="VWZ68_001750"
     CDS             complement(2772..3695)
                     /locus_tag="VWZ68_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEU9372739.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3692..4381)
                     /locus_tag="VWZ68_001751"
     CDS             complement(3692..4381)
                     /locus_tag="VWZ68_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEU9372740.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4446..5150)
                     /locus_tag="VWZ68_001752"
     CDS             complement(4446..5150)
                     /locus_tag="VWZ68_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9372741.1"
                     /translation="MVLSTLAILVACGKTDKEADAPTTFSYVYAVDPASLGYSITTRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPIVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKHIK"
     gene            complement(5206..6228)
                     /locus_tag="VWZ68_001753"
     CDS             complement(5206..6228)
                     /locus_tag="VWZ68_001753"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEU9372742.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6358..8829)
                     /gene="parC"
                     /locus_tag="VWZ68_001754"
     CDS             complement(6358..8829)
                     /gene="parC"
                     /locus_tag="VWZ68_001754"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEU9372743.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLRIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKNFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(9249..11192)
                     /gene="parE"
                     /locus_tag="VWZ68_001755"
     CDS             complement(9249..11192)
                     /gene="parE"
                     /locus_tag="VWZ68_001755"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEU9372744.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTALKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            11328..11969
                     /gene="plsY"
                     /locus_tag="VWZ68_001756"
     CDS             11328..11969
                     /gene="plsY"
                     /locus_tag="VWZ68_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEU9372745.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
BASE COUNT         3472 a         2734 c         2119 g         3720 t
ORIGIN      
        1 atcgctctga atatcaaaaa agaaaggacg aaatttgtcc tttctcgagc ttagcttttt
       61 ttcaacccac tacagttgac aaagagccag aaaaatcctt tgtttagtaa acaaaggatt
      121 ttgtgaattt tcaatttgat taaagttcga tatcaccaaa caaatcagcc attgaaaatc
      181 ctgtttgtgt ttctggaagt tcgaaatcac gcttttcttg acgtcttgga cgacgtggac
      241 gagcaacacg tttttcttct ttttgtcctt cttcttgggc tggacgttct tcaagagctt
      301 taatagaaag tgacacgcgt tctgcatctg cgttaacttc aagaacttta acttgaactt
      361 cttgaccaac tttaagagct tcttttggat tttcaatccg tttgtgtgaa atttgtgata
      421 cgtgaacaag tccatcgata cctggcaata cttcaacaaa tgcaccgaag tcagtcaaac
      481 gtttaactgt tccttctact acatcacctt tagccaattt ttgctcaacg ccatcccatg
      541 gtcctggtac tgttgcttta agtgaaagtg atacacgtcc ttcttcttcg ttaagatcaa
      601 ggattttcac ttcaatttct tcaccaacag ttacaactga ttttggtgat acattacgtt
      661 catgtgacaa ttcagtcaag tgaaccaatc cgtcaacacc accaagatcg acgaaagcgc
      721 cgaagcttgt gatacgagca actttaccag ttacaacatc accaacagcc aatttaccga
      781 atacttcagc gcgagctgct gcagtagctg cttcaacaac ttcacgacgt gaaaggatga
      841 agcggttttc tttagcgtta acttctttga ttttagtatc aaattcttga cctacaaaac
      901 gctcagcgtt acgtacgaaa cgagtatcca acattgaagc tgggataaat ccacgaacac
      961 cttcaaattc tactgaaagt ccacctttaa cggcacgcgt tcctttaaca gtaacaactt
     1021 cttcttcgcg accaacaagt ttgtcccatg ctttgcgagc ttcaaggcgt tttttagata
     1081 caaggtatgt aactgtatca gtatctttac caactacttg acgaagtaca agaacatcca
     1141 atacttctcc tactttaaca aagtcattga tatctgcatc acgatcgttt gtcaattcgc
     1201 gaagagtcaa gacaccttca acaccagttc cagagattgc aacgttagct tgagtcgcat
     1261 caactgtcaa tacttcagca ctaacaacat caccagtctc aacttgacta acgctattta
     1321 gcaaatcttc aaattcattc atctaaaaaa tcctccaaca atcaagtttt tcttaaactt
     1381 gacatactta taattttttt cctaagcacc cgcaaggaca tgttcatatc attcacgtct
     1441 ttcaattata aaaataaaat accctaagat attttgcttt ttatcttgat tattacctaa
     1501 gaactggggt agctggattc gaaccaacgc atgagggagt caaagtccct tgccttaccg
     1561 cttggctata ccccattaat gaaatggaga gagagggatt cgaacccccg aacccgaagg
     1621 agcggattta cagtccgccg cgtttagcct cttcgctatc tctcctacaa tcaacatgga
     1681 ctattatatc atgaaaattt caaaaaaaca agacttattt tgctaaatta taattttcaa
     1741 tcaaaatttc cacagctttt tccaattttt tataaaaact atcgacattc ccattcttta
     1801 taatggcaaa ttgtccgtct aattcggcaa tttctccgat aactttttta ccgatagtca
     1861 atgtataacc ttcaaaactg tctttaccaa cattaacttt ggcatccgct acttgaattt
     1921 cgattttttt atctttcttg ctcatttcat acctctcttc actttttcta ttttacaaga
     1981 aaatcctaaa actagcaaga aaaaactcta tatcaggctt ctctgatata gagttttatg
     2041 taaacaacct caatcgattt agcatagtta atagttagta aacaagcata attgactatc
     2101 ctttttaggt tatcagtgag tctcaccgcc tactaactgc aaatccttat ctttgtagtc
     2161 tacaatagct tcaatagcta cctctatgcc tcttacaata tcacatagac tcattcctgc
     2221 agtattcggc ttatttacta cttgttccat catatatgga atatgcatga aacctgctct
     2281 catattaggg aattttttat ccactaaata aagagcttgg tacatcaaat gattgcaaac
     2341 aaaggttcct gcactattgg atacaactgc cggaagtccc tgttttttga tagcttgtac
     2401 catcgctttg ataggtaaac tactaaaata ggccgatgct ccatcaatac gaatcggtgt
     2461 atcaattggt tgattgcctt cgttatcagg tatgcgagca tcatcttgat taatagccac
     2521 tcgttcaggt gttaagccgg tcctgccgcc tgcttgtcca atacaaagta cagcatctgg
     2581 ttgatatcgt aatatttctg cctctaaaac ttctgacgac ttataaaaaa ccgttggaat
     2641 ttctacccag cgaacttcag ccccattaat ctcagatggt aataatttta cagcctccaa
     2701 agctggatta atcttttcac ctccaaaagg attaaaacct gtaaccaata ttttcatttt
     2761 attttccttt actaaaatgc gagaaagtac attaagaata tgtgaataac aatcattact
     2821 agagcaacac ctgcttgagc ctttataacg ccattctgat ctttcatatc catcaatgct
     2881 gctggtagag cgttaaaatt agcagccatt ggggtcaata aggtcccaca ataacctgct
     2941 gtcatggcaa gagcaccagc cacaattgga ttagctccca gagcaaatac gaagggaact
     3001 ccaacacctg ctgtaataac ggtgaatgct gcaaaagcat ttcccataat cattgtgaat
     3061 agaaccattc caagaacata ggccaaaact cctataaagc gactatctga aggaacaata
     3121 ccgctaatca gatgagagat aacatcacca acacctgcta cagtaaaaat agcccccaaa
     3181 gcccctaata attgaggaac aatcccactt gttgaaactt gctgagtcat tcgattattt
     3241 tctgataaca gactcttagg gtgactattg gtaatcacaa gaacagaaat tgtagcaaac
     3301 aaggcggcaa ggctaatcga aatcttgcta aattctggaa tcatttgcgc taagaccaac
     3361 gcaagtattg ccatcagcat aactggaata aaaattttat ttttcaacct gttagattca
     3421 atattggctt tcatttcatc taaggatggc aaggttccga tacggacttg cttaaacaat
     3481 gttaacagcg ataataggat tacaataata ccaatactca tatttggcat ataggaacca
     3541 cctataaacg taatagacaa tagagtccaa aatgcagatg tcccaagtcg aactgggttt
     3601 gttttatctt tataactaca ataggctgta tggagaaatt gacaaccaat cacaatatag
     3661 gtcaactcta atagttgctt tgccaactct gtcatttttg ttctcctccc ctagtctttt
     3721 ttgatatcaa ttttttatca aataaataat tgtaaatccc cactacaata agtgttataa
     3781 cagcaacaat aatagatgta gaagcaatcc ctgcataatt gctttcatag cctaactgat
     3841 ctaatgttcc ccctatcaag aggactcccc cagcacctac aaacgtattt tgagcaaaga
     3901 aatttccaaa attttcattc gcagccgcac gcgcttttat tgtctcatct tcaacctctg
     3961 ttaactttct acctaattga gactctgcag ctgcttctcc cataggttga accaaaggtc
     4021 tgacaaactg agggtgtcct cctagacgaa ttgaaaagaa accagctaac tctcgaataa
     4081 agaaataaac tgtatagaag tttccaactg tcagaccttt aatctttcga atcaaatcga
     4141 ttgatcgttg cttgagtcca aaggtttctg acagccccac aagaggcaag gtaaccataa
     4201 aaatcgtgag cactcgctga ttgctaaatt cttttcccaa aatctccaaa aattcaacga
     4261 gagaaacacc tgaaactaaa gctgtaacca aaccagctaa gactactgtt gcaattgtat
     4321 caaattttaa aataaaaccc acaacaatga ttgctattcc tattaatcta atccactcca
     4381 tatcaaactc ctttatattc aaaatgacag tattttaaaa attttatcaa gatcaatacc
     4441 attccttatt taatgtgttt ttctagttct ttttggtatt tgctattgga ttccaatttt
     4501 tctttttgcc attttttaaa aacctcgtta tattcttttg ttgtaacaat atctttttgc
     4561 aatttcattc ctttaaagat atatggttcc cccttaatac caacttgtga gtatggtttt
     4621 gagaatggta ctacgttact tacaattgga gaaccaccag atgaagctgt tggcatcaat
     4681 aatgaactat ctgtcgacca agcttgagct ttggcatatt tttcatatct cttctctagg
     4741 tcagtggtct cagaaacagc atcttctaac aatttcttat atttatccaa accaggttta
     4801 gctacaacat ccttatcttt tcctttcgta ataccaaggt gtttcatggc agaaccagat
     4861 tttggatcca taatattcaa gtaagacgct ggatcttgat agcttggagc ccatcctgta
     4921 ctattcaaat catagtcttt ttgagaagga gcaacattgc cgtatttatc attttccatc
     4981 aaaccatcaa taacatttcc aataacgtct gtcgtcgatg ttcgagtcgt tatactgtag
     5041 cccaatgatg ctggatctac tgcatagaca taagaaaatg ttgtcggtgc atctgcttct
     5101 ttatcagttt ttccacaagc cactaaaata gctaacgtgc tcaggaccac tcctgctgtt
     5161 aagagccact ttttctattt cataaaaaat ctcctttggt ttattttaat ctacttttac
     5221 aatccaacct tctggcgctt caatatcgcc aaactgaata cccgtcaatt cattatataa
     5281 tttacgcgtc acaggaccta cttctgtttc actatagaat acatggaaat catcaccatg
     5341 ttgaatacct ccaattggag aaataaccgc tgctgtacca caggcacctg cctctacaaa
     5401 acggtcaaga ttatcaattg gaacatcacc ctcaatagga gttaatccca agcgatgttc
     5461 tgccaaataa agcaaggaat acttggtaat agatggcaag atagatggac tcaatggtgt
     5521 tacaaattca ttatcagctg taattccaaa gaaattagct gatccgactt cttcaatctt
     5581 tgtatgagtt gatgggtcca gatagataac atctgagaaa tggcgtgact tggccatttt
     5641 tcctggtaag agacttgcag catagtttcc accaacctta gccgcacctg taccatttgg
     5701 tgctgcacgg tcgtactcat cctgaatcaa gaagttggtt gggaccaaac cacctttaaa
     5761 gtaatttcca actggcatag caaagatggt gaaaatgtac tcttctgccg gttttacccc
     5821 gataatatct ccgacaccaa tcaaaagagg gcgaagatat aaggttccac ctattccgta
     5881 tggtggtacg tattcttcat tcgcacggac aactgcttta caagcttcta caaacatgtc
     5941 tgtcggaact tgtggcatca agagacggtc acatgtacgt tgcaggcgtt tagcattttc
     6001 atcaggacgg aacagttgaa cactgccatc cttagtacga taagctttca aaccttcaaa
     6061 tgcttgttgt ccatagtgaa gacttggaga agactctgaa atatgcaaag ttgcatcctc
     6121 tgtaagctct ccttgatccc attgtccatt tttgaaatga gcaagatagc gataaggtaa
     6181 tttcatatag gaaaaaccga ggttttccca atcaatcgtt actgtcatat tccactcctt
     6241 attctaaaaa cctatttctt atattctaca ctatttttct aaaatagcaa gtatattttg
     6301 taattttcag aaaattcctc caataaaaac catcttagaa ctgattcttc atttcactta
     6361 tttatcttca gtaactactt cctgaagata agcgtcaaaa acttcttcat ctgaaatcgt
     6421 gtcagaaatg aagcttccat tgctagtgcg ttctgacaag ttcaagtctt gcaatcggct
     6481 ttcatagatt gttcctttat tggattggac aagcagagtt tggtcgttca catccacttc
     6541 cgtactgaag aaatcgccaa caaatccttg ctctgcaact gctcctgcca agaagacacg
     6601 atgcggtttg tttttcaact cacgcaagac ttgtaatcct cgtttggcac ggctggttgc
     6661 tagaatttcc tcaatggaaa cacgtttcaa gcttccacgc tgggtcaaga ggtagaagga
     6721 cgaagtatta cagataaagc cagattggag gacatcatct tctttcaaat tcatagcctt
     6781 gacacctgct gccttagcac cgacaaccgg aacctcttcg atattgaaac gcagggcata
     6841 accattttga ctaaccaaga caacatcatc tagtttaatc ggagccactg ctacaatctg
     6901 atctgtatcg tctttgagct tagcatactt gacagactta gatctatagg tccgccatgg
     6961 agtgaattct tttcgctcta cccgtttgat ttgaccaagg cgagtcgctg caaagtaggt
     7021 tgtcgcatcg tcaaactgat ccagtacttc cacataaagg attgcttcat tcgtttcaaa
     7081 gtttgtgatg gtttggctca gatgctctcc gatgtccttc caacgaatat ctgccaactc
     7141 atggattggt ctgtagatga catttccaag acttgtgaac atcaagaggt gctgggttgt
     7201 cttggcagat tgaacaaaaa tcaaacggtc atcatcacgc ttgccaattt cttccaaggt
     7261 ggaagccgca aaggaacgtg gactggtacg cttgatgtaa cctgccttgg tcacgctgac
     7321 gtaggtatct tcctcagcga taagactagc tgtatcaatc tcaattgctt tcgcagtgtc
     7381 ttctaaagaa ctcaaacgag gagttgcaaa gttcttcttg acctcacgaa gttctttctt
     7441 catgagattg tacatagtcc tttcatcacc gataatagcc gccagcatag caatcttctc
     7501 acgaagctct gcttcttctt cctgcaagac aaccacatcg gtattggtca aacggtacag
     7561 ttgcaaagtt acgatagcct cagcctgttc ttccgtaaaa tcatagctaa ctttgaggtt
     7621 ttccttggcg tccgccttat tctcagaagc acggataaga gcaatgactt catccaaaat
     7681 cgaaatcaca cgaatcaaac cttcgacgat acggagacgt ttctcagcct tttctttgtc
     7741 aaagcgtgaa cgcgccaaaa tcacttctcg acggtgagcg atgtagctag acaggattgg
     7801 aacaatccca acctgacgag gtgtgaaatt gtcaatcgcc accatattaa agttgtagtt
     7861 gatttgtagg tcggtgtact taaataagta gttgagaaca agctcagtat tagcgtcttt
     7921 cttaagttca atagcgatac gaagaccatc acggtcagac tcatcacgaa cctcagcaat
     7981 cccagctacc ttgttattaa cacgaacatc atcgattttc ttgactagat tggccttatt
     8041 gatttcataa ggaatctcag taataacgat ttgttcctta ccacctttta gcttttcaat
     8101 ttcagtcttg gaacgaacaa ccacgcgccc tttcccagtc tcataggctt tcttgatttc
     8161 atcacgaccc tgaataatag cccctgtagg gaagtctggt ccaggtaaga attccatgag
     8221 tttatcaatc tttgcagttg ggtggtcaat catgtaaact gcagcatcta tgacctcagc
     8281 taaattatgg ggaggaatgt ctgtggcata accagccgaa atcccagtcg aaccattgac
     8341 caagaggttt ggaaaggctg ctggcaagac cgttggttct ttctccgtat cgtcaaagtt
     8401 ccatgcaaaa ggaactgtct ttttctcgat atcctgaaga aggtagcctg caatttcaga
     8461 caaacgtgcc tcagtataac gcatagccgc aggaggatct ccgtccatag aaccgttatt
     8521 accgtgcatt tcaactagaa tctcacgatt tttccagttc tgtgacatac gaaccatggc
     8581 atcatagata gaagaatccc cgtgtgggtg gaaattcccc atgatgttcc cgactgactt
     8641 ggccgactta cggtagctct tgtcaaaagt attgctatcc ttattcatag aataaagaat
     8701 acggcgttga accggcttca acccatcacg aatatctggc aaagcccggt cttgaataat
     8761 gtacttggag tagcgaccaa agcgctctcc catgatgtcc tccagggaca tgttttgaat
     8821 gttagacata agatacaaag cccataaaat accaagtgaa aatagaaaat tcttgaagta
     8881 agcaaactca caagagaatt tatctttttc acacagtatc tagggcgtgt tcaactcctt
     8941 tcaaagaatg tagagtaggt ttttatgcag taaaagatat tttacgggaa ttcgtcccgt
     9001 gttcagttac gataagtaac caaactatcc tgtttgtatt tttcaatatg aaaatctggt
     9061 tttccaaaat tagtcttagt ttgtgtctta accgctccct taagcgcctc tttaagataa
     9121 gcactcatag cagattcttc attaataatc ctgcaatttt ttcaaaccaa gattttcaaa
     9181 ctgctttttc acatagtcat tcacatccga ctctaatttc cagtttacta acatattatt
     9241 ttctttcatt aaaacactgt cgcttcttct agcgtaaact tgacattatc ttcaatccat
     9301 ttacggcgtg gttctacctt atctcccatg agaacattga cgcggcgttc ggcgcgcgct
     9361 aaatcttcaa ttgtgacacg gatgagggta cgtgtttctg ggttcatggt tgtttcccag
     9421 agctggtccg cattcatctc accaagtcct ttgtatcgtt ggagggtagc gcctttaccg
     9481 aactgtttac ggagttcttc tagttctccg tccgtccaag cgtaggccac ttcttctttc
     9541 ttgcctttac ctttggacat cttgtaaaga ggtgggaggg caatatagac atgacctgcc
     9601 tcgactagcg gacgcatgta acggtagaaa aatgtcaaga gcaaggtctg gatatgggca
     9661 ccgtcggtat ccgcatcggt catgataatg atcttatcat agttggcatc ttcaatagag
     9721 aagtctgctc caacacccgc accaatggta taaatcatgg tattgatctc ttcatttttg
     9781 aggatatccg ccatcttggc cttggctgta ttgataacct taccacgaag aggtagaata
     9841 gcctggaact tgcggtcacg accttgtttg gcagaaccac cggcagagtc cccctcaact
     9901 agatagagtt cattcttagc aggattctta gattgggctg gggtcaattt cccagacaac
     9961 aagcccttat ctttcttgtt tttcttccca tttcggctct catcacgcgc cttacgtgct
    10021 gcttcacgag catcacgggc cttgatagcc ttgcggatga ggttagaagc taattcccca
    10081 ttttccataa ggaaaaaggt caacttatca gccactattc catccacaac tgggcgagct
    10141 agggggcttc ctagtttatc cttggtctgt ccttcaaact gcaagtgttc ttcaggaact
    10201 aagatagaaa gaacggccgc tagtccctca cgatagtctg aaccttcaag gtttttatct
    10261 ttttccttga gaagacctgt tttacgtgca tagtcattca tgaccttggt aatggcagac
    10321 ttgagtcctg tctcgtgcgt tccaccgtcc ttggtgcgaa cgttattgac aaaggataga
    10381 atgttatctg agaatccgtc attgtactgg agggctactt ccacttgaaa accattgtct
    10441 tccccttcaa agtaaagaac tggcgtcaag atttccttat cttcgttgag ataagaaaca
    10501 aaatcttgta ctccattctc atagtggaac tcaatcgctt catctgttcg cttgtccgtt
    10561 aaagacaagg tcacattttt caagagaaag gctgattcat taaggcgctc tgaaatggta
    10621 ttgtacttga aatctgtcgt agaaaagata gtcgcgtcag gcataaaagt aactttggtg
    10681 cctgttttag acttgagtgc tgtaccgatt ttcttcaaag tcgtgacagg ttttccacca
    10741 ttttcaaaac gttgcttgta aactgcgcca tcacgggtaa tttcaacttc taaccagcta
    10801 gaaagggcgt taacaacgga agaacccact ccgtgaagtc cacctgatgt cttatagcca
    10861 ccttgaccga atttccctcc ggcatgaaga atggtaaaga taacctcaac agttggaatt
    10921 cccatagcgt gcatacctgt cggcatccca cgtccatggt cttgaaccgt tagactaccg
    10981 tctttattga tagttacatc aatacgatca ccaaacccag acaaggcttc atcgactgca
    11041 ttatcaacga tttcccaaac taggtgatga agaccagcgc catcggtcga tccaatatac
    11101 atccctggac gttttcggac cgcatccaac ccttctagca cctgaatagc atcatcatta
    11161 taattgttaa tattgatttc cttttttgac acaaggaacc tcctattcgt tcatctttac
    11221 tattctacag gttttccaag gattttgcaa aatttttctt tctccgatgt gacaatttca
    11281 gcagagattc tctgcttttc tttcccaatt catgatataa taggagtatg attacaatag
    11341 ttttattaat cctagcctat ctgctgggtt cgattccatc tggtctctgg attggacaag
    11401 tattctttca aatcaatcta cgcgagcatg gttctggtaa cactggaacg accaacacct
    11461 tccgcatttt aggtaagaaa gctggtatgg caacctttgt gattgacttt ttcaaaggaa
    11521 ccctagcaac gctgcttccg attatttttc atctacaagg cgtttctcct ctcatctttg
    11581 gacttttggc tgttatcggc cataccttcc ctatctttgc aggatttaaa ggtggtaagg
    11641 ctgtcgcaac cagtgctgga gtgattttcg gatttgcgcc tatcttctgt ctctaccttg
    11701 cgattatctt ctttggagct ctctatcttg gcagtatgat ttcactgtct agtgtcacag
    11761 catcgatcgc ggctgttatc ggggttctgc tctttccact ttttggtttt atcctgagta
    11821 actatgactc tctcttcatc gctattatct tagcacttgc tagtttgatt atcattcgtc
    11881 ataaggacaa tatagctcgt atcaaaaata aaactgaaaa tttggtccct tggggattga
    11941 acctaaccca tcaagatcct aaaaaataaa acgccagttc tgtactgccc ccaaacagtt
    12001 agacaaataa tttatccaaa ggatttagtt ctgtattgca caggg
//
LOCUS       DAVKEV010000050        11878 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVKEV010000050 DAVKEV010000000
VERSION     DAVKEV010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11878
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.050"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..674
                     /locus_tag="VWZ68_001757"
     CDS             <1..674
                     /locus_tag="VWZ68_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEU9372746.1"
                     /translation="KRIKRLRRISGGDTYTIIYLKLLLLSLKDEGKLYYDGVESDFIK
                     ELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTEIPNLIGSETAWAEKKRRYR
                     QNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYK
                     NLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYD
                     VGESL"
     gene            1358..1519
                     /locus_tag="VWZ68_001758"
     CDS             1358..1519
                     /locus_tag="VWZ68_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372747.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            1611..3290
                     /locus_tag="VWZ68_001759"
     CDS             1611..3290
                     /locus_tag="VWZ68_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU9372748.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            3558..4124
                     /locus_tag="VWZ68_001760"
     CDS             3558..4124
                     /locus_tag="VWZ68_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372749.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            4446..4634
                     /locus_tag="VWZ68_001761"
     CDS             4446..4634
                     /locus_tag="VWZ68_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU9372750.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            4696..5454
                     /locus_tag="VWZ68_001762"
     CDS             4696..5454
                     /locus_tag="VWZ68_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU9372751.1"
                     /translation="MVVYIRQSKLPSEVSINKYHAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            5512..6366
                     /locus_tag="VWZ68_001763"
     CDS             5512..6366
                     /locus_tag="VWZ68_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEU9372752.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            6478..7362
                     /locus_tag="VWZ68_001764"
     CDS             6478..7362
                     /locus_tag="VWZ68_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEU9372753.1"
                     /translation="MKKVMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            7501..7602
                     /locus_tag="VWZ68_001765"
     CDS             7501..7602
                     /locus_tag="VWZ68_001765"
                     /inference="COORDINATES: protein motif:HMM:NF014902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEU9372754.1"
                     /translation="MNTLGDKLMELSAIYHRPESEYAYLYKDKKLHI"
     gene            7666..9264
                     /locus_tag="VWZ68_001766"
     CDS             7666..9264
                     /locus_tag="VWZ68_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEU9372755.1"
                     /translation="MEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTE
                     GQNILYGDKGCVENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFAN
                     GNALLNPEGTLDWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSN
                     HKYNTTDYFEIDRYFGDKETFRELVDQAHHRGMKVMMDAVFNHIGSQSLQWKNVVKNG
                     EQSAYKDWFHIQQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATY
                     WIEEFNIDAWRLDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHA
                     VMNYPLSDSIKDYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWT
                     ANEDVQLVKSALAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNF
                     MKRLIKIRKYASVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEA
                     VALASNCQELENQLVISPDGFVIF"
     gene            9539..9994
                     /locus_tag="VWZ68_001767"
     CDS             9539..9994
                     /locus_tag="VWZ68_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372756.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            10439..10915
                     /locus_tag="VWZ68_001768"
     CDS             10439..10915
                     /locus_tag="VWZ68_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9372757.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            10915..11676
                     /locus_tag="VWZ68_001769"
     CDS             10915..11676
                     /locus_tag="VWZ68_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEU9372758.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSSVYDSGENTT
                     SAADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
BASE COUNT         4299 a         1638 c         2454 g         3487 t
ORIGIN      
        1 acaaaaggat aaaaaggtta aggagaatat ctggaggaga tacctatacg ataatctacc
       61 taaaacttct actactaagc ctaaaagatg agggcaaact ctattatgac ggagtagaaa
      121 gtgattttat aaaagagtta gcactaacca tagatgaaac agacgatgat gtaatggtaa
      181 cagtaaatta tttaatcaat caaggcttat tagaagttgt aacagaaaat gatgaatact
      241 acctaactga aataccaaac ttaatcggat cagaaacagc ctgggcagag aaaaaaagaa
      301 gatacagaca aaataaacag aggacattgt ccttaatgag tccaacccat gtccgacaag
      361 agatagagat agagaaagat atagagatag ataaagagag agagggagag atagataaaa
      421 agtccacccc cattttttat ggagaattca aaaatgtaag gttaagcaaa gaagaatata
      481 aaaatctaaa agaaaaatta aactcacaca cagatataat gataaataaa ctatccagat
      541 acatggaaag cagtggtaag acctatcaaa accactatgt gacaatctta aaatggtatg
      601 aagaagataa agacaaacta agacagaaag gtttaaataa aaaaatgaat tatgatgtag
      661 gagaatcttt atagataaaa agaggtggaa aggcactatt aaagacttta agtttaaaaa
      721 ggtatcaaag tatgccagag ataaaaaaat ataaatatga cactttaaag gcgattagaa
      781 aattaaagaa atgctagaag acttttagat gacagttacc aagagggtct aattttcact
      841 gctacttatg cagtaggaat tggacctttt tatataagca aattctattt caaaattggt
      901 taccaagaaa gacttctttt cactgttaag tataagaggg taatttatag aattttgtta
      961 catcaagata aatattttct gatggtcaaa ttttaaaaag attaataact ctcgataaat
     1021 tttgaacctt aacaattgaa tagaccaaga caagacgtta attatttttg gagcgtaata
     1081 acctatccgt caagatcttt cggctgaata attcggcaaa aaaagttctg ctaagcaaaa
     1141 agaaagtgag cgataagtaa gagtttgaat atagggaggg ataccctatc cgctatgaag
     1201 aaaatgagga taatgatact tctaaggttg aagccggctc atccggaata gaggcggagg
     1261 tgagattcct atgttgctaa tccaaagcac ttgtcaatgt caaaaaactt aattaaacaa
     1321 ataattatta gatataaaac tttagaggag gtatatattg gacaatgact ggaatggatt
     1381 ggctgattta atagcaaatc tgattgcaaa atatgctggt gctttagatt tagataatct
     1441 acccgatcca acgccagcaa aaaatcaaga gatgaaaaat agttttgaca tggcaaaaac
     1501 acaaattgag acggactaat aaaagtgtta taatatactt gaaatgatag tccaaactta
     1561 aattaaaaaa attatatatg atatagaaaa attatattga ggttaatact atgtcaaaag
     1621 aaaaaataaa agtatacctc tatacacgag tatctacgtc aatacagata gaggggtatt
     1681 cgttagaggc acaaaaatca cgaatgaaag cttttgctat ttacaacgat tatgaaattg
     1741 ttggagagta tgaagatgcc gggaagtctg gcaagtctat tgaaggtaga atacagttca
     1801 atcgaatgat ggaagatata aaatctggaa aagatggagt atcttttgtt cttgtgttta
     1861 agttatcaag atttgcaaga aatgccgctg atgttctttc tacacttcag ataatgcagg
     1921 attatggagt taatcttatc tgcgttgaag atggcattga ttcatctaaa gatgctggga
     1981 aactaatgat ttctgtttta tcagctgtgg ctgaaataga aagagaaaac atccgtattc
     2041 aaacaatgga aggttgcatt caaaaagcaa gggaaggaaa atggaatggt ggctttgctc
     2101 cgtatggata taaacttgaa gacggcaagc tgtttataaa tgaggaagag gcagttgcaa
     2161 taagaacgat tttcgaccag tatgtaaata ctacgatagg agccaatggg atatctaaat
     2221 acttagagaa tcatggaatt agaaaaatcc caagacagaa tggtaagaat cctttgtttg
     2281 atgcaggtct tataagaaag atattaaaga atcctgtata taatgggaaa atagcatttg
     2341 gaagaagaac tttagaaaaa gttcatggta caagaaatga atataagcag gttgaacaag
     2401 atgaatatct aatatctgaa gggatacatg aagctatagt ttccgatgaa gtttggcaag
     2461 ctgctcaggt taagctaaaa tctcaagcaa agaaatatga gcatgtgaat aaaggaaaag
     2521 atacacgcac acacttgctt tctggaattg taaaatgccc gatatgtgga gtgggaatgt
     2581 ttgggaacaa gtgtatcaag aaaaagaaag atggcacaaa gtataaagat ttttattact
     2641 atggttgtaa acataggcag atgataagag gtcataagtg tacattcagt aagcaaatta
     2701 gagaagaatt gttagatgat gctgttgcag aggtgattgt caagatagta agtaatccga
     2761 aatttgcttc tatgatgcaa gaaaaaatca acatgaaggt ggatacctct gaaatagaaa
     2821 aagaaataga taattaccaa aaggaattga gaaagagtca ttctacaaag tttaagctaa
     2881 ttgaggaaat agataattta gatgttgaag ataagcacta taagagaagg aaacaggatt
     2941 tagatgatag actatatcgt atgtatgaca aaatagatga attagaatca tcactaattg
     3001 atgcgaaagc aaagaaacag actattgaag ctgaaaaact tacaggagat aacatatata
     3061 aggttctgat ctattttgat aagctctata aagtcatgaa tgatgtagag cgtaggcagt
     3121 taatttcagc tttgatttct gaaattcaag tttatgaaga aaaacaatct aacggacaat
     3181 ggctaaaatc cattactttt aagctaccaa ttatagaaga aaatctcaac atagatttgg
     3241 acaatgatga acaagttgaa tgtgtaagtt tattagagaa acgtagttaa tcctcaaaag
     3301 gttccccaaa ctttttgagt cccactgacg catcacgctg aggcggtatc actgcttgta
     3361 cgagttgaag catcagcgaa gtaaaagtag atgttcagcc aatgcgacga ggtgagaccg
     3421 aaggtcgata aggtgtgttc tgggtatagg actcgtaaag taagtaggaa atatgatgag
     3481 atgatacaga gagcctgaat tggtcaggtg acgtgcttat ttacattagc ctgataatga
     3541 aaatggagag attatcgatg gttatattgg aattgtacca aaatgattat tctaaagatt
     3601 tagtagcatt tgattccata gaagatggga aagcctttgt ggctcaaatc ccgggataca
     3661 ctctggaaac agaagatggt tttgaagtgg agtattttaa tcctaaaaac ataccggatt
     3721 atatggaaat tatttttaac ggaaatattg ttcctttatc taaatttatg ttcgatcctg
     3781 aggaaaatgt aaacattatt tggaaagaga tttcaaattt atccctcaaa aatgatagag
     3841 tgatcgaagg atattcaaaa attgatgcat atgtcgttaa caaccatgaa gttaaagcct
     3901 atgtcgaaac aagagaaacg aactatcgta aagcaaaaga cttcttagaa agccgcggat
     3961 atgaaatcga cagaagcttt ttcggaagtg aagacggtga agcgattctt tacagaaaaa
     4021 aagggatcga agtttggcat ttcttgtgtc acttagaccc aatgtttgta gagattgaag
     4081 atgtagaagg atatgttaaa gaagaagttg gagagattca atagtcaacc aaagttcctt
     4141 gtgagtatat acctttgcta gtaaaagagt caaaacgtta taacgaaggg ggggaagaaa
     4201 acccttgagt gtaagtcttt ttcttgttta gagggaaagt attagagtag ccgctcataa
     4261 tttatactag atttgataac tgatttgaga cagattttat ttctataaat attgtgaaaa
     4321 ttttttaata ccaaagattt aaagttactg tgttaaaaat cctctccact tttaaactaa
     4381 tgtattataa aagccagttg acacaagtgt tacacctgtg atagaattaa cttgaggtga
     4441 tgaaaatggc aaccgataaa aatagaataa tgattagctt ggatgataaa aatctagaga
     4501 aacttgaaaa tttagtagaa gatgctagag atagaagggg aatgcgacta acaaagtccc
     4561 aggttattga attactccta aataccgttg attatttcga tgatattatg ggggctattt
     4621 actcaaaaaa ataagagcaa aattgctatt attttttaca aattggtgta acactagtga
     4681 tataggagtg atgaaatggt tgtttatatt agacaaagta aattaccaag tgaggtttca
     4741 attaataaat accatgctca agtaggtgcc tacttacaag gagaagaagc tgttttatat
     4801 caatcttttt ctgaaataaa agagttaaca agtgaagata tagttgtaga ttatataatg
     4861 gagactagag cattactaaa aatgatgggc ttaaacgttc cggttcatga ctatcctatt
     4921 gagcttaaag agttttatgg tcgaaagatt tatgctggta ttttaggaga gattgtgaat
     4981 atacctgata attggggaaa atttattaag cctaaagctg gttcaaaagt ctttactgga
     5041 agagttgtta atggaaccca tgatttaata ggtattggtc tacctttcga ctatcctata
     5101 tggattagtg aggttgtaga attcatagct gaatggcgtt gttttgtgtt agatggtcgc
     5161 gtattagatg ttcgacccta tacaggtgat tatcatgcac aatttgatgc aagtgtaatt
     5221 gatgaagcga tatcatgttg gaaagatgcg ccaatagctt atggactaga tatcggtgtt
     5281 actcgcgatg gcagaacact tgttgttgaa gtaaatgatg gttatgcatt gggaaattat
     5341 ggcctatctc ctttaaaatc aatcaatttt catagagcta ggtggaaaga aatggtaaaa
     5401 ccctattttg aaaaaaatga aatttttaaa atccaacagg atgttgtttt ctaaaataaa
     5461 tatggtatat aaccaatata aaaagcatca aaatgaacaa ggaggaatct gatgcttgga
     5521 gcaattattg gagatattgt cggttctgtt tacgaatgga acaatatcaa aacaaaggac
     5581 tttcctttat ttcggaagga ctgctttttt acagatgaca cggttatgac ctgtgctgtt
     5641 gcagaagcaa ttatgaatgg tggacaaaaa gacgatttca ttgacgcgat gaagaaatat
     5701 ggcagaatgt atccgaatgc tgattacggt gctcggttta atgcatggct aaacagcgat
     5761 aaccgtgagc cttataatag ctttgggaat ggatcagcta tgcgtatttc tccatgtgct
     5821 tggatcatgg actgtggttt ttatgcgaaa actggtatgt ggccatcatc tagaggactt
     5881 acgagtcttt ctgcagaggt aactcataat catccagaag gtgtcaaagg cgctatggct
     5941 acagctgatg ctatctttct atgtcgtttt tactttggtg gttattgtag agagtacgag
     6001 caatcaatta acgacaatcc tacagagtgt aaaagacgaa ttaaggatta tatagaaaaa
     6061 gaatacgatt acaatctatc tcaaacttta gatgaaatcc gtcctaacta tcgttttaac
     6121 gaaacatgtc aggaaactgt ccctcaagcc attatcgcct ttcttgaaag tagagacttc
     6181 gaagatgcga taagaaatgc catctcactt ggtggcgaca gtgatactct cgcagcaatc
     6241 acttgtaaca tagcagaggc agcttacggt attcctgatt ggatcaagga taaggcctat
     6301 tcttacttgg atgaaccctt aaaggatgta gttaggcgat gggaaaatag aataaaagcg
     6361 tattaatctc cagtacgtca gatttctctt ttctgtattt tcattgtata ataggattac
     6421 atttacttgc atacgacgaa atgtaaacat ttctgtttaa aattaaggat aaaatcaatg
     6481 aaaaaagtaa tggtaattat caaccctact tctggtggcg agaaggcttt ggattacaaa
     6541 gaaaagctgg agaataaagc aaaagaatac tttgaatatg ttgaaaccaa aattaccgaa
     6601 aaagcgctgg atgcaacaca ttttgctgaa gaagcttctc gtgagcagta tgatgcagtg
     6661 gttgtgtttg gtggagatgg aactgtcaat gaagtcattt caggtattga tgagagagac
     6721 tacattccta agttagggat tatcccaggc ggtacgggta acctcattac aaaacttttg
     6781 gaaatcaatc aagacatcga tggcgcaatt gacgaactgg attttgattt aaccaataag
     6841 attgatatcg gtaaagcaaa tgacaactat tttggttata tctttagtat cggttctctg
     6901 cctgaggcga ttcacaatgt tgaaatagag gacaaaacaa aattcggtat tttaacctat
     6961 gctgtaaata ccatgaagtc tgtcatgaca gatcaggtct ttaacattaa ggttgagaca
     7021 gaaaatggaa attatgttgg tgaagctagc catgttttgg tccttttgac aaattacttc
     7081 gctgataaga aaatctttga agaaaacaag gacggctatg ccaacatttt gattctgaaa
     7141 gatgcctcta tattctccaa attatccgtc attcctgatt tattaaaagg ggatgttgtc
     7201 gcaaatgata atatcgagta tatcaaagcg cgtaatatta aaatctcttc agatagtgaa
     7261 ttggagtcag atgttgacgg agataaatca gataacctac ctgtagaaat caaagtccta
     7321 gctcagcgag tagaagtatt ttcaaaaccg aaagaggatt agtatataga gaaagccttt
     7381 tttaaggctt tttgtatact ttaaaagata gttcctttaa caacggacat tccttgcaaa
     7441 tagtttacaa aaatagtata ctggatttat tgagtttgaa aacgtttgcg taaaatttga
     7501 atgaatactt taggagacaa attgatggaa ttgagtgcta tttaccatag gcctgagtcg
     7561 gagtatgcct atctttataa ggataagaaa ctccatattt gaattcgaac taagaaaggg
     7621 gacattgaaa gcatcaactt gcactatggg gaccctttta tctttatgga ggagttttat
     7681 caggatacaa aagaaatggt caagataact tctggtacct tatttgacca ttggcaggtt
     7741 gaagtgtcag ttgactttgc acgtatccag tatctctttg agctcagaga tacagaaggt
     7801 caaaatattt tgtatggcga taaagggtgt gtggaaaatt ctctagaaaa tcttcatgca
     7861 attgggaatg gatttaagtt gccttatctt catgagattg atgcctgcaa ggttcctgac
     7921 tgggtttcaa atacggtatg gtatcagata tttcctgaaa gatttgccaa tggcaatgct
     7981 ctattaaacc cagaagggac tttagactgg gattcatctg tcacacctaa gagcgatgat
     8041 ttctttggtg gtgatttaca ggggattatt gatcatatgg attacttgca agacttgggt
     8101 attactggac tatatctttg tcccatcttt gaatctacaa gcaatcacaa gtacaatacg
     8161 acagattact ttgaaattga ccgttatttt ggagacaagg agacctttcg ggaactggtg
     8221 gatcaagcgc atcatcgtgg catgaaagtc atgatggatg cggtatttaa tcatattggt
     8281 tcgcaatctc ttcaatggaa aaatgtcgtc aaaaatggcg aacagtctgc ttataaggat
     8341 tggttccata ttcaacaatt cccagtgaca actgaaaagc tagttaataa gagagactta
     8401 ccctatcatg tttttggttt cgaggactat atgcctaagc taaatacagc caatccagag
     8461 gtcaagaatt atcttttaaa ggttgcgact tattggattg aagagtttaa tatcgatgct
     8521 tggcgtttgg atgtggctaa tgagattgac catcagttct ggaaggattt tcgtaaggca
     8581 gttttagcta aaaatcctga tctttatatc ctaggagaag tctggcatac atctcagcct
     8641 tggctaaatg gagatgagtt ccatgccgtc atgaattatc ctttatctga tagtatcaag
     8701 gactatttct tacgaggaat taagaagaca gaccagttca tcgatgaaat caatggagag
     8761 tctatgtatt acaagcagca gatttcagag gtcatgttta atctcttgga ttcacatgat
     8821 acagagcgaa tcctgtggac ggccaatgaa gatgttcaac tggttaaatc agccttagcc
     8881 tttctctttt tacaaaaagg aacaccgtgc atttattacg gaaccgagct agccttgact
     8941 ggaggaccag atccagattg tcgtcgttgt atgccttggg aacgtgtatc aagtgacaat
     9001 gatatgctga actttatgaa gaggctgatt aagattcgga aatacgcgtc agtaatcatt
     9061 tcgcatggca agtatagcct tcaagaaatc aaatctgatc tagtagctct ggaatggaaa
     9121 tacgaaggac ggatcctcaa agcaatattc aaccaatcaa cagaagatta tcttttagag
     9181 aaagaagcag tagcactagc aagcaattgc caagaattgg agaatcagct tgtcatctct
     9241 ccagatggat ttgtgatttt ctaaaaacta gttgatgaag attatggtac atttcatatc
     9301 ttatatagta taataaggct agttactaaa cttgtaaagg agaacttaaa tgaattgtag
     9361 aggacatgaa acaagacaaa gaattgttag agattttgaa gtttagccta aagcacatat
     9421 taagctgtta gcaaatcaac aaaaacatag tgatgcagga gcaactattg aagatgaata
     9481 ttatgtattt atcgctgaga gtaaaattga tggcaagaag gaagttattc agtgttgcat
     9541 gggtgcggca agggattttt tagaactaat taatcacaaa gggctacctc tttttaatcc
     9601 gcttgtaggt gattctcatg taaataatag acaagaatat gacaatacag ggagtggaaa
     9661 tttacaacct gaaaagtgga atgaaactgc aaagcagctt tataatgcta taatgtggtt
     9721 gattatttta tggaatgcta agccggatac acctttattt aattttaaag acgaagtaat
     9781 taagtataaa acatatgagc cttttgaaag cagtataaaa agagtaaata ctactataaa
     9841 gaatggtagt aaagggaaaa ctctgactga gatgattaat ggctacagag cggataacga
     9901 tattagagat gaaatttgta actttaatat tctgaaaaat aaaattcgtg atatgaaaga
     9961 ccaacaagga aatacaatgg aatcttactt ttagttattg ttgaattttg ggtattctat
    10021 aaaatatcct aattgagatt taaatagtag actatacaat atagttaaaa tatcagtaaa
    10081 aacaacactt tattgaggta ttggatacgc tttgctaata gcctaataat cacatgtgga
    10141 gtgttgctac aacgaaaaag gtgataatcc ttaatttcaa gctattttat aagcattttg
    10201 tctttgtaga taaaggcaat tttgacaata aaaatcctaa aaggtgaatc gttatagatg
    10261 tatttgtaga tattgtttgc gcatcgaaaa aattaataca agaataaata tttatagctc
    10321 tttaggtgac ttttatagaa gtaaagttta ggatagaaaa acaagaaata acgcaccatt
    10381 tttggtgcgt tatgcttttt tatgctataa tggatttata aaaataaagg agtttgctat
    10441 gattggaaag aacataaaat ccttacgtaa aacacatgac ttaacacaac ccgaatttgc
    10501 acgaattata ggaatttctc gaaatagtct gagtcgttat gaaaatggaa cgagttcagt
    10561 ctctaccgaa ttaatagaca tcatttgtca gaagtttaat gtatcttatg tcgatatcgt
    10621 aggagaagat aaaatgctca atcctgttga agattatgaa ttgactttga aaattgaaat
    10681 tgtgaaagaa agaggtgcta atctattatc tcgactctat cgttatcaag atagtcaggg
    10741 aattagcatt gatgatgaat ctaatccttg gattttaatg agtgatgatc tatctgactt
    10801 gattcagaca aatatctatt tagtagaaaa ttttgatgaa atagagagat atagcggcta
    10861 tttggatgga attgaacgta tgttagagat atctgaaaag cggatggtag cttaatggaa
    10921 atccaagatt atactgatag tgaattcaaa catgctttag caaggaatct tcgttcactg
    10981 acaagaggaa aaaagtccag taaacaacct atagcgattt tgcttggagg tcaaagtggt
    11041 gccggtaaga ctacaattca tcgtattaaa cagaaagaat ttcaaggaaa tattgttatc
    11101 atagatggtg atagttttcg ttctcagcat ccacactatt tagaactgca gcaagaatat
    11161 ggcaaagaca gtgtagaata taccaaagat tttgcaggaa aaatggtaga gtctttagta
    11221 acaaaattga gtagtttgag atacaatctt ttgatcgagg gaactttacg aacagttgat
    11281 gttccaaaga aaacagcaca actcttgaaa aataagggat atgaagtaca attggcctta
    11341 attgcgacaa agcctgaatt gtcgtatcta agtactctta tccgttatga agaactgtac
    11401 attatcaatc caaatcaagc acgcgcaact ccaaaagaac atcatgattt cattgtaaat
    11461 catctagttg ataatacacg acaattggaa gaactggcta tctttgaaag aattcaaatt
    11521 tatcaacgag atagaagttc tgtatatgat tcaggagaaa atacaacttc agcagcagat
    11581 gttcttcaag agttactgtt tggggagtgg agtcaggtag agaaggagat gttgcaggtg
    11641 ggggaaaaga gacttaatga attacttgaa aaataaacaa ttgatatttt taggagagta
    11701 gaaatgagag ggtttaataa caagataaag tctgtttatc aagaactaac aaattccaaa
    11761 gagaaattcg gtagctttca caagacttta attcatttgc atacacctgt ttcttatgat
    11821 tacaagctat tttctaattg gactgcaacg aaatatagaa aaattactga agatgaac
//
LOCUS       DAVKEV010000051        11655 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVKEV010000051 DAVKEV010000000
VERSION     DAVKEV010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11655
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.051"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..154)
                     /locus_tag="VWZ68_001770"
     CDS             complement(<1..154)
                     /locus_tag="VWZ68_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9372759.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVY"
     gene            248..808
                     /locus_tag="VWZ68_001771"
     CDS             248..808
                     /locus_tag="VWZ68_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEU9372760.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            810..1709
                     /gene="htpX"
                     /locus_tag="VWZ68_001772"
     CDS             810..1709
                     /gene="htpX"
                     /locus_tag="VWZ68_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEU9372761.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(1858..3417)
                     /locus_tag="VWZ68_001773"
     CDS             complement(1858..3417)
                     /locus_tag="VWZ68_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9372762.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEICSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(3656..3973)
                     /locus_tag="VWZ68_001774"
     CDS             complement(3656..3973)
                     /locus_tag="VWZ68_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU9372763.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FGF"
     gene            4143..4685
                     /locus_tag="VWZ68_001775"
     CDS             4143..4685
                     /locus_tag="VWZ68_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEU9372764.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENEALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            4685..5314
                     /gene="nth"
                     /locus_tag="VWZ68_001776"
     CDS             4685..5314
                     /gene="nth"
                     /locus_tag="VWZ68_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEU9372765.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            5525..6046
                     /gene="pyrR"
                     /locus_tag="VWZ68_001777"
     CDS             5525..6046
                     /gene="pyrR"
                     /locus_tag="VWZ68_001777"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEU9372766.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            6065..6988
                     /locus_tag="VWZ68_001778"
     CDS             6065..6988
                     /locus_tag="VWZ68_001778"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEU9372767.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            7038..8117
                     /gene="carA"
                     /locus_tag="VWZ68_001779"
     CDS             7038..8117
                     /gene="carA"
                     /locus_tag="VWZ68_001779"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEU9372768.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            8430..11606
                     /gene="carB"
                     /locus_tag="VWZ68_001780"
     CDS             8430..11606
                     /gene="carB"
                     /locus_tag="VWZ68_001780"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEU9372769.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDTLIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIKSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         3344 a         2304 c         2558 g         3449 t
ORIGIN      
        1 gataaacttc ttccttgtcc gtaatcgccg tcaaattaat cttctcattc cactcgacca
       61 agagctcaaa ataacgttca aattgttctt tttgctggtc cgaaagtgga agattctgct
      121 cggcaagcaa gttgtaaaat gtttttggtt tcatagttat ttccttcttt agtatcatct
      181 tattttacca caatcataga aaatttgata tactggtact aatctaaaag cagaaaggac
      241 ttatattatg acttggatta ttcttggagt tatcgctctt attgttattt ttgtgattgt
      301 tagctataac ggtttggtta aaaatcgtat gcaaaccaag gaggcttgga gtcagattga
      361 tgttcagttg aaacgtcgaa atgacctctt gccgaacttg attgagactg taaaaggtta
      421 tgccaaatat gaaggttcta cccttgaaaa ggtggcagaa ctacgtaacc aagtggcggc
      481 agcgacttca ccagcagaag ctatgaaagc cagtgatgcc ctcactcgtc aggtttcagg
      541 tatttttgca gttgcagaaa gctatccaga tttgaaagct agtgctaact ttgttaaatt
      601 gcaagaggag ttgacaaaca cagaaaataa aatttcttac tctcgtcaac tctataacag
      661 tgttgtcagc aactacaatg taaaattaga aactttcccg agcaatatta tcgctggaat
      721 gtttggattt aaagcggcag atttccttca aacacctgaa gaggaaaagt cggttcctaa
      781 agttgatttt agcggtttag gtgactaaga tgttgtttga tcaaattgca agcaataaac
      841 gaaaaacctg gattttgttg ctggtatttt tcctactctt agctcttgtt ggttatgcgg
      901 ttggttatct ctttataaga tctggacttg gtggtttggt tatcgcactg attatcggct
      961 ttatctacgc tttgtctatg atttttcaat cgacagagat tgtcatgtcc atgaatggag
     1021 cgcgtgaggt ggatgagcaa acggcaccag acctctacca tgtagtggaa gatatggctc
     1081 tggtcgccca gattcctatg ccccgtgttt tcatcattga tgatccagcc ttaaatgcct
     1141 ttgcgacagg ttctaatcct caaaatgcgg ctgttgctgc gacttcaggt ctactagcta
     1201 tcatgaatcg tgaagaacta gaagctgtta tgggacatga agtcagtcat attcgtaatt
     1261 atgatatccg tatttcgact attgcagttg cccttgctag tgctatcacc atgctttcta
     1321 gtatggcagg tcgtatgatg tggtggggtg gagcaggtcg cagacgaagt gatgatgacc
     1381 gagatggaaa tggtcttgaa atcattatgc tagtggtttc cctactagct attgtactgg
     1441 cacctctcgc tgcaaccttg gttcagctcg ctatttctcg tcagagggaa tttctggcag
     1501 atgcatctag tgtcgagctg actcgcaatc cccagggaat gattaatgcc ctagataagt
     1561 tggacaatag caaacctatg agtcgccacg tcgatgatgc tagcagtgct ctttatatca
     1621 atgatcccaa gaaaggtggg gggttccaaa aactctttta tacccaccca cctatctcag
     1681 aacggattga acgtttaaaa cagatgtaaa atgaaggctg gaaaaaagtc tttaaaatct
     1741 gaaaaacgca taatatcagg tgtgaaaact tgatattatg cgttttacta tgggaagatt
     1801 tacttctttt tctcctaaaa ttgtgttttt gccccaccta tctgctatgt tgcaaattta
     1861 taaatcttct aaattaacta gcttcaaacc gtgttctgtc atgcgataga tgatcgagca
     1921 gatttctttt aagaaacgac ggtcatgcga aacagtgatg agaccgcctg gataggttgc
     1981 aaagagtttt ctgatttggg gttgagaagt gggagaaaag tttcgtgtgg gttcatccag
     2041 caggagaaag tttggtttgc gcaggactaa atccaaaagc aggagttttc cctgttgtcc
     2101 gccagataag gagcgaattt gatgctgcat ttctggataa ctgaaattga gactggctag
     2161 gtgagattgg attttctgaa gttcctcttt ttccccagtt ttgctgatat aagctattgg
     2221 tgataaatcc aattgcagtt ttttgtggta atcttgtggc ataaaaccaa gggaaatctc
     2281 tcttttatca ttcagaagtt gctttaattt ggctaacaga gttgatttcc caacaccatt
     2341 tggcccgata ataccgattt tttcttgccc acggacagtt agttgtagtt tttgaaccaa
     2401 aactcggtcg tcaatggaca aattttcttt ttccagttgg actaagactt tagaagctgg
     2461 taatggttgg atgtctgaaa agaaaagttg gatttgttcc tcttcaagtg gcttttgagt
     2521 catggactga gctgtctttt cgtagcgttt ttcttgtgag aggacagttt tcatcttttt
     2581 agccaatagg cgaccggcag tactatcttt ggtagctcga agcgcagttt ctacattttg
     2641 cttaactctc cgatgttttt ccatggtttt atcgtaggct ctttggttgt tagcagcttg
     2701 ctgactttgt ttggcaaaat tagcctttct ctgctcacta tagctatcat agtctaaatg
     2761 ctctactagc gtttccgctt ctttacggtg tttgaccagt cgcaagtgaa caatagtgtc
     2821 tgctgtttca gaaagaaagt cttcatcatg ggaaatgaaa ataacggttt gcctggtctt
     2881 ttgaatctgg ccttttagcc aatcaactgt ctcaaggtct aggtcatttg aaggttcatc
     2941 taaaaataga atctcaaagg gtttggctaa ctcatggata agctgaattt tcaaagcttc
     3001 tccccctgat agattgccaa tcttttggtc acttgcgaaa cgattgctat caaaatgcaa
     3061 ttcctccgcc aaacgataga ggatactgta gtctaaatca atagaatcta aaaagaagta
     3121 gtcgtgtaaa gttttctttt tcagctcctc gggaagtttt tgaggaatgt aggccagtga
     3181 ctgatagtca gattggatgt ttcccttgat agtgaaatca gacaaagctt cccccattaa
     3241 aattttaagt aaggttgatt tgccatttcc ttcttcacca ataatagcaa ccttttcccc
     3301 gtcttggatg gtcatgctta ggtcagatac aagatctcgt aaatctttgt tttgtgtgat
     3361 ggttagatga ttgattttta tcatatgatt tccctttcta gaatgttcat agtgcataac
     3421 aaaaagctct actttaccta gtagagccca aagtctatgt caaaaaaact ctattaacat
     3481 gccagaaaaa gagcataaaa gagcacacaa aaagagacaa aaacaagatc tactaaataa
     3541 aggttcttta tttgatagac ttagttgttc atgtctccct tacctccgag tattagtatc
     3601 tttatattat acctttaagg aaattttgtc aacagaaaac tggaaattct atgctctaaa
     3661 atccaaaaac aggtccatag agacttagta cgtgtttgac atgctcgtaa tggaatttat
     3721 catagtttcg ccaagcagtg cgtgcttgat cgtttagttt taggctaccc agtccaatca
     3781 gaagactggt gggttggtaa aatttctcaa gatcaattaa gatactgttg ttcaactttt
     3841 ccgttttttt gagctcttgc atagtagtgt ttagcagctc ttgtagtcga atatcatctg
     3901 ccgtaccctg tttacagttt tggtagcttt tatttaactt ggataggagt tgaatgagtt
     3961 tcttgtcttc catgtgagca tcctccttga tctgatgtac tctttcccta tagtatagca
     4021 ctaaaaaaca aaactgtcat agtaaatatg ttaaaattct gaattttaat tacaaagttt
     4081 ggtgtgctga tttgtagcct tttcatggta taatcaagag agtaaatctt tatggaggaa
     4141 gtatgaaatt aaatattcaa gaaattcgta agcagtctga aggtttgaac tttgaacaaa
     4201 cgttagattt agttgatgac ctgcgtgcac gtaatcaaga aattttagat gtaaaagata
     4261 tccttgcagt tgggaaagta caatatgaag accgtatgta tttcttagat tatcaactat
     4321 cttataccat tgttcttgct tcgagtcgca gtatggagcc agttgagtta gttgaatctt
     4381 atccagtcac ggaagttttc atggaaggcg caactaacca tctaaatcaa gaaattttag
     4441 atgatgactt ggtcttgccc atcgaaaatg aggcgcttga ccttgctgag agtgtatcag
     4501 acaatatctt gctaaacatt cctatcaagg tcttgacggc tgaagaagaa gctggtcaag
     4561 gatttgtctc aggaaatgac tggcaaatca tgacagagga agaataccaa gctcaacaag
     4621 cagtaaagaa agaagaaaac agtccttttg ctggcttaca aggactattt gacggagatg
     4681 aataatggtc ttgtcaaaaa aacgagcacg aaaggtgcta gaagaaatca ttgccctctt
     4741 cccagatgcc aagcctagtc ttgattttac caatcatttt gaactcctgg ttgcggtcat
     4801 gttatcagcc cagacgacag atgcagcggt aaataaggcc acaccaggtc tctttgttgc
     4861 ctttccaaca ccccaagcta tgtctgtagc gacagagagt gagattgctt cacatatttc
     4921 tcgcttggga ttgtatcgga ataaagctaa attccttaaa aaatgtgccc aacagttact
     4981 agacgatttt gatggtcaag tccctcagac acgtgaagaa ttggagagtt tggcaggtgt
     5041 tggtcgcaag acagccaatg ttgtcatgag tgtaggattt gggattccag cctttgcagt
     5101 tgatactcat gtggagcgta tttgcaaaca ccacgatatt gtcaaaaaat cagcgacgcc
     5161 acttgaggtg gaaaagcggg tcatggatat cttgccgcct gagcagtggt tagctgccca
     5221 tcaggccatg atttattttg gaagagccat ttgccatcca aaaaatccag agtgtgacca
     5281 gtacccacaa ttatatgatt ttagcaattt gtaagatgct acattgaaac tttttgcttg
     5341 attttaagca tgctttgtgc tatagtaaat gataactaaa tattccttta aacctgtccc
     5401 gtgaggcagg caaggagcgc gataaagtag aagggtgaag tctatactgt gtgcagtagg
     5461 gctcgcttgg ctataaattt caagtctcct tgtttaagga gacttttctt tttggaggtt
     5521 tgtcatgaaa acaaaagaag ttgtagacga attgaccgtc aaacgagcga ttacgcgtat
     5581 tacttatgag attatcgaac gcaacaaaga tttgaataag atcgtcttgg ctggtattaa
     5641 aactcgtggt gtctttattg cccaccgaat ccaagaacgt ttgaagcagt tagaaaatct
     5701 ttcagttcct gttgtggaat tggatactaa acctttccgt gatgatgtta aaagtggaga
     5761 agatacttct ttggtttctg tcgatgtgac agaccgcgaa gttatcttgg tggatgatgt
     5821 gctctataca ggtcgtacca tccgtgctgc tattgataat attgtcggtc atggtcgtcc
     5881 tgcgcgtgtg agtttagcag ttctagtcga tcgtggacat agagaattgc caatccgtcc
     5941 agattacgtt ggaaaaaata tcccaaccag tcgttctgaa gaaatcatcg tagagatgac
     6001 agaacttgat gaccaagaca gagttctgat tactgaagaa gcttagaaag ttaaaggagt
     6061 agccatgtca gaaaatcaac aagcattgaa ccatgtggtg tccatggaag acctcactgt
     6121 cgatcaagta atgaaattga tcaagcgagg aattgagttt aaaaatggag cccagcttcc
     6181 ctatgaagac catccgattg tttccaatct cttctttgag gattctacac ggacacataa
     6241 gtcctttgaa gtcgcagaga ttaaacttgg attggaacga cttgactttg atgtgaagac
     6301 tagttcggtt aataagggtg agacacttta tgacaccatt ttgactctgt ctgctttagg
     6361 agtggatgtc tgtgtgattc gccatccaga ggtcgactac tatagagaat tgattgctag
     6421 tccaacgatt acgacttcca tcatcaatgg tggagatggt tcgggccaac accctagcca
     6481 gagcttgctt gatttgatga ccatttatga ggaatttggc cactttgagg gtcttaaagt
     6541 tgctattgca ggtgacttgg accactcacg cgttgccaaa tccaatatgc agattttgaa
     6601 acgcttggga tctgaactct ttttcgctgg acctgaggaa tggagaagtc aagagtttgc
     6661 agactatgga cagtttgtaa ccattgatga aatcattgat caggttgatg tcatgatgtt
     6721 tctccgtgtg caacacgaac gccatgatag tggagctgta ttttcaaaag aagactacca
     6781 tgcccaacat ggcttgactc aagaacgtta cgatcgtttg aaagaaacag caatcctcat
     6841 gcacccagct ccaatcaatc gtgatgtaga aatagcagac cacttggttg aagcaccaaa
     6901 atcacggatt gtccaacaaa tgaccaatgg tgtctttgtt cgaatggcaa tcttagaatc
     6961 cgtactagcg agtagaaacg ccaactaaaa cacaagacgt taaaagacgc cagtgagcgt
     7021 ccacgagagg tgaaaatatg acaaaaagaa ttctagtatt agaagatggc acagtttttg
     7081 aaggcaaggc cttcggagca gatattgatg taacaggcga aatcgtcttt aatacaggga
     7141 tgaccggcta ccaagaatcc attacagacc agtcttataa tggacaaatc ttgaccttta
     7201 cttatccttt ggtaggaaat tatggtatta atcgtgatga ttatgaatcc attattccaa
     7261 cttgtaaggg agtcgttgtt tttgaagaag cgcgtagagc tagcaactgg cgcaaccaaa
     7321 tgaccttgga tgaatttttg aaagccaaga aaattccagg gatttcagga attgatacgc
     7381 gtgctcttac caagattatc cgtaagcatg gtactatgcg tgcaaccttg acccatgttg
     7441 gggacagtat ggaccatgtg acggaccagc tccaagcaac agttttaccg acagacaata
     7501 tcaaacaggt ttctactaaa acgtcttatc cagctccagg agttggtttg agcgtggtgc
     7561 tagtggactt tggtctcaag cactcaatcc tacgtgaact ttctaaacgc aactgtaacg
     7621 tgacagttgt tccttattcg acaacggctg aagaaattct ccatctcaat cctgacggag
     7681 ttatgttgtc aaatggtcca ggtaacccag aagacgttcc acaagcactc gacatgattc
     7741 gcggtgtaca aggaaaaatt ccaatctttg gtatttgtat gggacaccaa ctctttgcaa
     7801 tggcaaacgg ggctaagacc tataagatga agtttggcca ccgtggattc aaccatgcgg
     7861 tacgtgaaat cgcaacagga cgagtagact tcaccagcca gaaccatggt tatgcagtca
     7921 gccgcgagga tttgccagag cacttgatta ttacccacga agaaatcaat gacaagtcag
     7981 tggaaggtgt gcgccacaga taccaacctg ctttctctgt tcaataccac ccagatgcag
     8041 ctcctgggcc acacgacgct agctacctat ttgacgagtt tatcgagatg atggaagttt
     8101 ttaaacaatc aaactaagaa cgagtaaaag ctcgtcggag aatttatgta actgaacacg
     8161 gacggaaagc tcagaatgta gagaaaccaa cttggattgt caatccttcc ttgatttcct
     8221 aaaattcaat cgctttctat tcgtcctttg tatcttattt aatgtcgccc tgagaggcga
     8281 cgaatagaaa ggagaaggga gctccgtatt tgctgaactg aatacgggct acggacggtg
     8341 ctaaaaagat agttattcct agaactgaca gttcttcgtc ataactccta ttttagcttt
     8401 gtccgcttga cacccttaat atcttatata tgcctaaacg tactgatatt caaaaaatta
     8461 tggtgattgg ttctggtccg attattattg gtcaggctgc tgagtttgac tacgctggga
     8521 ctcaggcttg cttgtcgttg aaagaggaag gttatgaggt tgttttggtt aactcaaatc
     8581 ctgcaaccat catgacggac aaggaaattg ctgacaaggt ttacattgaa ccgattacac
     8641 ttgagtttgt gacacgtatt cttcgtaagg aaggtccaga tgccttgcta ccaacactcg
     8701 gtggtcagac aggtctcaac atggccatgg aattatctaa aaatggtatc ctagacgagc
     8761 ttggcgttga acttctgggt accaaattat ctgccattga ccaagcggag gaccgtgatc
     8821 tctttaaaca attgatggaa gagcttgaac aacccattcc agaatctgaa attgttaaca
     8881 cagtagaaga agcagttgcc tttgcagcga caattggcta cccagtcatc gttcgtccag
     8941 cctttaccct tggtggtact ggtggtggta tgtgtgccaa cgagaaagaa ttgcgtgaaa
     9001 tcactgaaaa tggtttgaaa ttgtcacctg ttacccaatg tttgattgag cgttcgattg
     9061 ccggtttcaa ggaaattgaa tacgaagtga tgcgtgactc agctgacaat gccttggttg
     9121 tttgtaacat ggaaaacttt gacccagttg ggattcacac aggggattcc attgtatttg
     9181 cccctgcgca aaccatgtca gactatgaaa accaaatgct tcgtgatgcg agcttgagca
     9241 ttattcgtgc cctcaagatt gaaggtggat gtaatgttca gctagctctt gatcctaaca
     9301 gcttcaagta ttatgttatc gaagtaaacc ctcgtgtatc acgttcgtca gcccttgctt
     9361 ctaaagcgac aggatatccg attgctaagt tggctgccaa gattgcagta ggtttgacct
     9421 tggatgaggt tataaaccca gttacaggtt caacctatgc catgtttgaa ccagcccttg
     9481 actacgtagt tgctaagatt ccacgtttcc catttgacaa gtttgaaaag ggtgaacgcc
     9541 gtctcggtac acaaatgaag gcgactggag aagtcatggc aatcggtcgt aacatcgagg
     9601 aatctcttct caaggcctgc cgctcccttg aaattggggt gcaccacaat gaaatacctg
     9661 aacttgcagc agtttctgat gataccttga ttgaaaaggt tgtcaaagcc caagatgacc
     9721 gtctcttcta cgtatcagaa gccattcgtc gtggctacac acctgaagaa attgcagagc
     9781 ttacaaaaat tgatatcttc tatcttgata aactcttgca tatctttgaa attgagcaag
     9841 aattgggtgc tcatccacaa gatctagaag ttttgaaaac agccaaactt aatggttttt
     9901 cagaccgtaa gattgctgaa ctctggggaa cgactgatga taaagttcgc caacttcgct
     9961 tggaaaacaa gattgttcca gtttataaga tggtagacac ttgtgcggca gagttcgatt
    10021 ccgaaacgcc atatttctat tcaacctatg gttgggaaaa tgaatctatc aaatctgata
    10081 aagaatctgt acttgtccta ggttcaggtc caatccgtat cggtcaaggg gttgagtttg
    10141 actacgcaac cgttcactct gttaaggcta tccaggcagc tggttatgaa gctatcatca
    10201 tgaactcaaa cccagagacc gtttcaacag acttctctgt atcagataag ctttactttg
    10261 agccattgac attcgaagat gttatgaacg tcattgactt ggaacaacca aagggagtta
    10321 tcgttcagtt cggtggtcaa acagccatca accttgcaga gccattggca aaagcaggtg
    10381 tgaccatcct tggtacacag gttgctgacc tagaccgtgc cgaagaccgt gacctcttcg
    10441 agcaagctct caaagaattg gatattccac agccaccagg acaaacggct accaatgaag
    10501 aagaagcagc tcttgcagct cgtaagattg gcttcccagt tcttgtccgc ccatcttatg
    10561 tacttggtgg acgtgccatg gaaatcgttg aaaacgaaga agaccttcgt tcttacatgc
    10621 gaactgctgt taaggctagt ccagaccatc cagttcttgt cgactcttat atcgttgggc
    10681 aagagtgcga agttgatgcc atttcagatg gtaaaaatgt actcattcct ggtatcatgg
    10741 agcatatcga acgtgctggt gtccactcag gtgactcaat ggctgtttac ccaccacaaa
    10801 ccttgtcgca aaaggttcag gagaccatcg cagactacac caaacgctta gcaatcggtc
    10861 ttcactgcct tggaatgatg aacatccagt ttgttatcaa ggatgaaaaa gtctacgtta
    10921 ttgaggtcaa tccacgtgcc agccgtaccg ttccattcct atctaaggta accaatattc
    10981 ctatggctca agtagcgacc aagctcattc ttggtcaaag tttatcagaa cttggctacc
    11041 aaaatggact ttaccctgaa agcacccgtg ttcatatcaa ggcacctgtc ttctccttta
    11101 ccaaactagc taaggtagac agcttgctcg gtcctgaaat gaagtcaaca ggtgaagtta
    11161 tgggttctga tgctactttg gaaaaagctc tctataaagc ctttgaagct tcttatctac
    11221 acttgccaac ttttggtaat gtcgtcttta ccatcgctga tgatgccaaa gaagaagcct
    11281 tgaacttggc tcgtcgtttc caaaacattg gttatggaat ccttgcgaca gaagggacag
    11341 cagccttctt tgctagtcat ggcttgcaag cccaacctgt tggtaagatt ggtgatgacg
    11401 ataaggatat cccaagtttt gtacgcaaag gaagaattca agctatcatt aacacagtag
    11461 gaacaaaacg aactgctgac gaagatggtg agcaaattcg tcgttcagcc attgaacacg
    11521 gggtgcccct cttcacagcg ctagatacag ctaatgccat gcttaaggta cttgaaagtc
    11581 gtagctttgt tacagaagcg atttaaatag aaaaataaga tatagcagac tgaatttaga
    11641 acagtacaca gggat
//
LOCUS       DAVKEV010000052        10912 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVKEV010000052 DAVKEV010000000
VERSION     DAVKEV010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10912
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.052"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            16..699
                     /locus_tag="VWZ68_001781"
     CDS             16..699
                     /locus_tag="VWZ68_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9372770.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            699..1433
                     /locus_tag="VWZ68_001782"
     CDS             699..1433
                     /locus_tag="VWZ68_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9372771.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESRKVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            1587..2444
                     /locus_tag="VWZ68_001783"
     CDS             1587..2444
                     /locus_tag="VWZ68_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEU9372772.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            2586..3458
                     /locus_tag="VWZ68_001784"
     CDS             2586..3458
                     /locus_tag="VWZ68_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEU9372773.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            3740..4423
                     /gene="rpiA"
                     /locus_tag="VWZ68_001785"
     CDS             3740..4423
                     /gene="rpiA"
                     /locus_tag="VWZ68_001785"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEU9372774.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            4437..5648
                     /locus_tag="VWZ68_001786"
     CDS             4437..5648
                     /locus_tag="VWZ68_001786"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEU9372775.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAEINPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            5650..6207
                     /locus_tag="VWZ68_001787"
                     /pseudo
     CDS             5650..6207
                     /locus_tag="VWZ68_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199123.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            6207..7016
                     /locus_tag="VWZ68_001788"
     CDS             6207..7016
                     /locus_tag="VWZ68_001788"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU9372776.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            7492..7887
                     /locus_tag="VWZ68_001789"
     CDS             7492..7887
                     /locus_tag="VWZ68_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEU9372777.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEIIEPAQADDIRKVVGELAKDISITKLYMTGHSLGCYLAQIAAVEAYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            7897..8472
                     /locus_tag="VWZ68_001790"
     CDS             7897..8472
                     /locus_tag="VWZ68_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU9372778.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            8497..9009
                     /locus_tag="VWZ68_001791"
     CDS             8497..9009
                     /locus_tag="VWZ68_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEU9372779.1"
                     /translation="MSAQITINHKKARYVRIGLEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            9667..10377
                     /gene="deoD"
                     /locus_tag="VWZ68_001792"
     CDS             9667..10377
                     /gene="deoD"
                     /locus_tag="VWZ68_001792"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU9372780.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(10400..10912)
                     /locus_tag="VWZ68_001793"
     CDS             complement(10400..10912)
                     /locus_tag="VWZ68_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEU9372781.1"
                     /translation="MIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSDHEWM
                     LTDIKNFLTKHKAWVIDGNYSWCCYQERMQEADQIIFLNFSPLTCLFRTFKRYLKYRG
                     KVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRELDQF
                     LDKKRKSYNS"
BASE COUNT         3282 a         1937 c         2527 g         3166 t
ORIGIN      
        1 gaaagcagtg tgactatgaa tttttctttt ttacctaagt atttacctta ttttaactat
       61 ggggctgttg tgacgattct tatttctatc tgtgttatct ttttgggaac tattttgggt
      121 gttgtcttgg cttttgggca acgttcaaag tttaaaccgc ttgtttggtt ggccaacttg
      181 tacgtttgga ttttccgtgg gacaccgatg atggttcaaa ttatgattgc ctttgctctt
      241 atgcatatca atgctccgac tattcagatt ggaattttag gtgttgattt ttcgcgtctg
      301 attccaggga ttttgattat ctctatgaat agtggtgctt atgtttcgga gactgttcgt
      361 gccggaatca atgcggttcc aaaaggtcag ctagaggcgg cttattcgct agggattcgt
      421 cctaaaaatg cgatgcgtta tgtgattttg ccacaagcag tcaaaaatat cttgccagca
      481 ttggggaacg aatttatcac cattatcaag gacagctccc tcttatcagc tattggggtc
      541 atggagttgt ggaatggggc tacaacagtt tctacaacaa cctatctacc tttaacacca
      601 cttttatttg cagcatttta ctacttgatt atgacctcta ttctgacagt agccttgaaa
      661 gcttttgaaa aacatatggg acaaggagat aagaaataat gacagaaacc ttgataaaaa
      721 ttgaaaattt acataaatct tttggaaaga atgaagtatt gaagggcatc aacctcgaga
      781 ttaaaagagg agaagttgtc gttatcatcg gtccttcagg gagtgggaaa tctaccttgc
      841 ttcgctctat gaatttgttg gaggaagcaa ccaaggggaa ggttatcttt gagggagtcg
      901 atattacgga caagaagaat gacctgtttg ccatgcgtga gaagatgggc atggttttcc
      961 aacaatttaa cctctttcct aatatgactg tgatggaaaa tattaccttg tcacctatca
     1021 agactaaagg tgaaagcagg aaagttgctg agaagagagc ccaagagctt ttggaaaaag
     1081 ttggtttgcc agataaggca gacgcttatc cacagagtct gtcgggtggg caacaacaac
     1141 ggattgccat cgcgcgtggg ttggctatgg aaccagatgt tttgctcttt gacgaaccaa
     1201 cttcagcctt ggatcctgaa atggtaggtg aggtattggc tgttatgcaa gaccttgcca
     1261 agtcagggat gactatggtt atcgtaacac atgagatggg atttgcccgt gaggtggcag
     1321 atcgtgttat ctttatggca gacggtgtgg ttgttgaaga tgggacacct gagcagattt
     1381 ttgaacaaac ccaagaacaa cggactaaag atttcttgag taaggtttta taatctattt
     1441 taaaatttca agacaagatt agtgaaaagt tcaaccagag ctttttctta tagtttgaaa
     1501 ctataggata acctaggaaa gaagtgttag agggcactag cagtttttgg tataatggaa
     1561 gatatttgaa agaaaagaga agtgatatga cacagattat tgatgggaaa gctttagcgg
     1621 ccaaattgca ggggcagttg gctgaaaaga ctgcaaaatt aaaggaagaa acagctctag
     1681 tgcctggttt ggtagtgatt ttggttgggg ataatccagc cagccaagtc tacgttcgca
     1741 acaaggagag gtcagctctt gcggctggtt cccgtagcga agtagtgcga gttccagaga
     1801 ccattactca agaggaattg ttagacctga ttgctaaata taatcaggat ccagcttggc
     1861 atgggatttt ggtccagttg ccattaccaa aacatatcga tgaagaggcg gttttattag
     1921 ccattgaccc agaaaaggat gtggatggtt tccatccctt aaacatggga cgtctttggt
     1981 ctggacatcc agtcatgatt ccctcgacac ctgcaggaat tatggaaatg tttcatgaat
     2041 atgggattga cttggaaggt aaaaatgcgg tcgtcatcgg tcgttcaaat atcgttggaa
     2101 aacctatggc tcagcttctt ttggctaaaa atgcgacagt aaccttgacc cactcacgaa
     2161 ctcataatct tgccaaggtg gctgctaaag cagatattct tgtagtcgca atcggccgcg
     2221 ccaagtttgt gactgctgac tttgtcaaac caggtgcggt tgtcattgac gttgggatga
     2281 accgagatga aaatgggaag ctctgtggag atgttgatta tgaggcagtt gcaccacttg
     2341 ctagctatat cacgccagtc cctggaggtg tcggtcctat gaccattacc atgctgatgg
     2401 agcaaactta tcaagcagca cttcggacat tggatagaaa ataagagaaa cattcgatta
     2461 atagagtgta ttttctatag ctatatctaa aatggcagaa atgaatatta aattttagat
     2521 ataagattac aaaaggaggt ctgcgtctcc tttttattgt ataataaaag tgagaggaaa
     2581 aaaggatgaa agtgattaat caaaccttat tagaaaaagt tattattgaa cgttctcgtt
     2641 caagtcataa aggagattat ggtcgtctgc tgctgcttgg tggtacttat ccttatggag
     2701 gtgccatcat catggctgct ttagcagctg taaaaagcgg tgcaggattg gtgaccgttg
     2761 gaacggacag ggaaaatatc ccggctctgc acagccattt acctgagcct atggcctttt
     2821 ctcttcaaga ccagcaattg ttaaaagagc aattggagaa ggcagaagtt gtcttgttgg
     2881 ggcctggttt acgagacgat gcttctggag aaaatctagt aaaacaggtc tttgttaatt
     2941 taagccaaaa tcagattttg attgtagacg gaggtgcctt gaccattctt gctaggacaa
     3001 gtttgtcatt tccctcaagc cagcttatcc taactcctca ccaaaaagaa tgggaaaaat
     3061 tatctggaat tacgattgaa aagcaaaagg aagatgcaac ggctagtgtt ctgacttcct
     3121 tccctcaagg aacaattttg gtggagaaag gcccagctac tcgtatttgg gaagttggcc
     3181 aatctgatta ttaccagtta caggttggtg gtccttatca ggcgactggg ggaatgggag
     3241 atactctggc tgggatgatc gcaggatttg taggccaatt ccgacaggcc agtctctacg
     3301 agcgtgtggc agtagcgacc catcttcatt cagccatagc ccaagaacta tctcaggaaa
     3361 attatgtggt cttaccgacg gaaatcagca ggtatcttcc caaaataatg aaaattattt
     3421 gtcaacaaga gagggtaagc aaagataaac ttgtttaaaa tagacagata aatctacttc
     3481 cttctcttaa tttatgattc ttgaaatgcg cctgctttaa ggctaaacta gacgtatcaa
     3541 agttaagagt ttgtttttgt aactggaaag agatgaacaa atcaaataca taaaagataa
     3601 actcattttt attcgtttgg taaaaataaa atgcatattt ttaaagaaag attgatgaaa
     3661 aatgtagatt tgatgttttt acttgaataa aaagcggttt catagtaaaa taagaactga
     3721 gaatgatgga ggtaaatcgg tggaaaatct gaagaaaatg gcaggtatca aggctgctga
     3781 gttcgtgagc gatggaatgg tcgttggact tggaacaggc tcgactgcct attattttgt
     3841 cgaagaaatc ggtcgtcgta tcaaggaaga aggattgcag attacagctg taacaacttc
     3901 tagtgtgacc actaaacagg cagaaggcct taatatcccg ctcaagtcta ttgaccaagt
     3961 agactttgtc gatgtgacgg ttgatggcgc ggatgaagtg gatagtcagt ttaatggaat
     4021 caaaggcggt ggtggtgccc ttctcatgga aaaggtggtc gcaacaccat caaaagaata
     4081 catttgggtg gtggatgaaa gcaagctggt cgaaaaacta ggtgctttta aattgccagt
     4141 agaagtggtt cagtatggtg cagagcaggt ctttcgtcat tttgaacgag ctggctacaa
     4201 accaagtttc cgtgaaaaag acggccaacg ttttgtgacg gatatgcaga attttatcat
     4261 tgacctcgcc ttggatgtca ttgaaaatcc aattgctttt ggacaagaat tggaccatgt
     4321 cgttggtgtt gtggagcatg gtttattcaa ccaaatggtg gataaggtaa tcgttgctgg
     4381 acgagatgga gttcagattt caacttcaaa aaaaggaaaa tagaaggggg cataagatgt
     4441 ctaaatttaa tcgtattcat ttggtggtac tggattctgt aggaatcggt gcagcaccag
     4501 atgctaataa ctttgtcaat gcaggggttc cagatggagc ttctgacaca ctgggacaca
     4561 tttcaaaaac agttggtttg aatgtcccaa acatggctaa aataggtctt ggaaatattc
     4621 ctcgtgaaac tcctcttaag actgtagcag ctgaaatcaa tccaactgga tatgcaacaa
     4681 aattagagga agtatctctt ggtaaggata ctatgactgg acactgggaa atcatgggac
     4741 tcaacattac tgagcctttc gatactttct ggaacggatt cccagaagaa atcctgacaa
     4801 aaatcgaaga attctcagga cgcaaggtta ttcgtgaagc caacaaacct tattcaggaa
     4861 cggctgttat cgatgatttt ggaccacgtc agatggaaac tggagagttg attatctata
     4921 cttcagctga ccctgttttg cagattgctg cccacgaaga cattattcct ttggatgaat
     4981 tgtaccgtat ctgtgaatac gctcgttcga ttacccttga gcgtcctgcc cttcttggtc
     5041 gcatcattgc tcgcccttat gtaggtgaac caggtaactt cactcgtacg gcaaaccgtc
     5101 gtgacttggc tgtatctcca ttttccccaa ctgttttgga taaattgaat gaggctggta
     5161 tcgatactta tgctgtgggt aaaatcaacg atatctttaa cggtgctggt atcaaccatg
     5221 acatgggtca caacaagtca aatagtcatg gaattgatac actattgaag actatgggac
     5281 ttgctgagtt tgaaaaagga ttctcattca caaacctagt tgactttgat gccctttacg
     5341 gccatcgtcg taatgctcac ggttaccgtg attgtttgca tgagtttgat gaacgcttac
     5401 ctgaaattat cgcagctatg agagagaatg accttctctt gattactgcg gaccatggaa
     5461 atgacccaac gtatgcaggg acggatcaca ctcgggaata tattccattg ttggcatata
     5521 gccctgcctt taaaggaaat ggtctcattc cagtaggaca ttttgcagat atttcagcga
     5581 ctgttgccga taactttggt gtggaaactg ctatgattgg ggaaagtttc ttagataaat
     5641 tggtataaga tgacgcgcta tgctttgctg gtgagaggta tcaatgttgg tagtaagaat
     5701 aaggtcgtta tggcggagct tcgtcaagaa ttgacaaact tgggactgga aaaggttgag
     5761 agctacatca acagtggcaa tattttcttt acttcgatag attccaaagc ccaattggtt
     5821 taaaagctag agactttctt tgcagtccat tatccattta ttcagagctt ttctttactg
     5881 agtctagagg actttgaggc ggaacttgaa aatctaccag cttggtggag cagagacttg
     5941 gcacgaaaag attttctctt ttacactgag ggtttggatg tggaccaagt catcgcgaca
     6001 gttgaaagtt tagagctgaa agatgaagtg ctttatttta gaaaacttgg gattttctgg
     6061 gggaaatttt ctgaagaatc ctattctaag actgcctatc ataagtactt gctgaaggtg
     6121 cctttctacc gccacattac tattcgtaat gctaaaacct ttgacaaaat tggtcaaatg
     6181 ctaaaaaata ataaaggaga cacataatga catttttaaa caaaatccat gaaactgcta
     6241 ctttcctgaa agaaaaggga attgcagccc ctgagttcgg tctaatcctt gggtcaggac
     6301 ttggagaatt ggcagaagaa atcgaaaatc cagttgtagt agactatgct gagattccaa
     6361 actggggccg ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt gaactggcag
     6421 gtcgcaaggt cttggctctt caagggcgtt tccatttcta tgaagggaat cctctggaag
     6481 tggtgacttt cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt attgtaacca
     6541 atgcagctgg cggtatcgga tttggtcctg gtaccttgat ggctatctca gaccatatca
     6601 acatgacggg gcaaaatcca ttgatgggtg aaaacttgga tgactttggc ccacgtttcc
     6661 cagatatgtc tagggcctac acaccagaat accgtgccac tgcccatgaa gtggctaaaa
     6721 aacttaatat caagcttgat gaaggtgtct atatcggagt tactggtccg acttatgaaa
     6781 caccagcaga aattcgttcc tataagacac tgggagcaga tgcagttggt atgtctacgg
     6841 ttcctgaagt tatcgtggcg gcccactctg gcttgaaagt tctgggaatt tcatgtatca
     6901 ctaactttgc ggccggtttc caagaagaac tcaatcacga agaagttgta gaagtgactg
     6961 aacgtgttaa aggtgatttc aaaggcttgc ttaaagcgat tcttgctgaa ttgtaagaaa
     7021 aaagatttaa aagggggagt gcctctgttt tttcaggatt gactgcctat ccggattaaa
     7081 gaagaaacag aggaatacta tgagcttctt cctgctctta taactgaaag aagcggaaga
     7141 ataggtgtgt ctgatctgat agccagcatt gtgaaagaca agattctagg atactagcat
     7201 tagcttccta gccaagtaga ctagtatgat aaggagagat gagaatgaat tgactttctg
     7261 aatttctcag tcttatcata tatagcacaa tgagatttcg cttgagtctg cttgtaaata
     7321 aacgaaaaga aagataagaa ataatgaaaa ttggtcaacg aattatgcgc tttggcataa
     7381 aaaattaagt atcggagttg tatctgttgt agtcggcttt gatttctagc tccagctgga
     7441 atttcagcca atgaagtaaa gcaagatgta acatctgaag tggtaatagg tgtgctagat
     7501 tctaaggagg aattgaaaga gtcagaaaat gatgctccaa aactagaaac tcctcttaga
     7561 gaggagccaa gactagctcc tcaaacgctt ccggaagcaa gtgaagttct tgaaaacaaa
     7621 agggaagagt caaaagtaga gataatagag ccagctcaag cggatgatat ccgcaaggtt
     7681 gttggggaat tagccaagga tataagtatt actaagttgt atatgacagg tcattctctt
     7741 ggatgttacc tagctcagat tgcagcggtt gaagcttacc aaaaatatcc tgatttttat
     7801 aaccatgtat tgaggaaagt gacaactttc agtgctccta aagtgattac ttccagaact
     7861 gtttgggatg ctaagaatgg tttctgagat gttggtttgg aaagtcgtaa attagctgtt
     7921 agtggaaaaa ttaagcatta tgtggttgat aatgacaatg ttgtgactcc cttgattcat
     7981 aataatcgtg atattgttac atttacaggt aattcacgct ttaaacaccg ttctcgtggc
     8041 tattttgaaa gtccaatgaa tgatattcct aactttaata ttggtaaaca agctaccttg
     8101 gataaacatg gttatcgtga tccgaaattg gataaagtgc gattctttaa gaaacaggct
     8161 ctacctcaat cttctagtca accaagcgct gaaccaatgg aaaatattgc cttaggaaaa
     8221 caggttactc aaagttcgac agctttcgga ggagatgcta gaagagctgt ggatggcaaa
     8281 gtcgatggta actatggtca caattctgtc actcatacaa acttccaatc taagccttgg
     8341 tggcaagtag atttggctaa agaagaaacc attcgccaaa tcaatattta caaccgaaca
     8401 gacactgccc aggatagatt ggcaaacttt gatgtcattc ttttagacag ttctggtaaa
     8461 gaaattgagt gaaaacgtat aatatctcct aaagatgtgt cagcacaaat tacgattaac
     8521 cataaaaaag cgcgctatgt tcggattggg ctagaaggct ataatgccct cagtcttgca
     8581 gaagttgaag ttttccgctt tatagctacg aatgctgaaa cggcgacaca agtttctaag
     8641 ccagttcaac caatcagtca gactcctgtg aaagataaaa cattgacaat tcaacacagt
     8701 ggagcttaca ttgcccgcta ctccataact tgggaagaag ttacagtaga taaagatgga
     8761 aaccaagttg ttcgtagtca ttcttgggaa ggaaacggtc gcaaccagac tgcaggtttt
     8821 gtcctcaacc tcccaatcaa agaaaatatg agaaatctgc gagttaagat tgagaaaaag
     8881 acgggcctac tatggaatag atggcaaaca atctatgaaa acagaccaat tttagctcaa
     8941 ccccaccgta aaattaccca ttggggtacg acattgaatt ccaaggtgag tgacgatgat
     9001 gtcttgtaat ctgatggtac aatgacagtt agtttgtcta gtttataaga aagtactacc
     9061 tgagcttgaa tagaactcag gtagctctct gtgaaagaac aaaattaata ctcaatgaaa
     9121 atcaaagagc aaactaagaa actagccgca ggttgctcaa agcactgctt tgaggttgta
     9181 gataagactg acgaagtcag tcacatatat aatccaaggc gacgttgacg tggtttgaag
     9241 agattttcga agagtataaa cagaaaggta gagcgcgtgt tctaatttga acacgagtag
     9301 aaaacttttc taaaaataaa aacgaaagga tgggtaaact gtattcgctg aactgaatac
     9361 gggcgactct cctctaaatc aaaattaaga aagaaaggaa ttgaccccac cctaaaagca
     9421 gtgggaaaaa gatagttggt ctagcgagca tcgctcactg cgcccaactc ctattttccc
     9481 ttcgcttttt gatgggtttg gtatctttct caatataaaa tataaaataa agaaaggtag
     9541 agcgtgtgtt ttgatttgaa cacgagcgga aaactcggaa aatagataat ctgactgaaa
     9601 aatcaggatt tctcgtcagg ttcctaattt tcagtcgttt tcttctcgct ctttgtatca
     9661 taaattatgt ctatccatat tgctgctcag cagggtgaaa ttgctgataa aattcttctt
     9721 cctggggatc ctcttcgtgc taagtttatt gcggagaatt tccttgatga tgctgtttgt
     9781 tttaacgaag tgcgtaacat gtttggttac actggtactt acaagggtca ctgtgtatct
     9841 gtcatgggaa ctgggatggg aatgccatct atttcgattt atgcgcgtga gttaatcgta
     9901 gactacggtg tgaagaaatt gattcgtgtg ggaactgcag gttctttgaa tgaagaggtt
     9961 catgttcgtg aattagtttt ggcgcaggcg gctgcaacca actcaaacat cgttcgtaat
    10021 gactggccac agtacgattt tccacaaatt gctagctttg atttgcttga taaagcctac
    10081 catatcgcca aaaaacttgg tatgactact cacgttggga acgttttgtc atctgatgtc
    10141 ttttactcaa attactttga aaagaatatc gagcttggta aatggggagt caaggctgtg
    10201 gaaatggaag cagcagctct ttactatctt gctgcccaat accatgttga tgcgctagct
    10261 atcatgacca tctctgatag cttggtcaat ccagacgaag acacaactgc agaagaacgt
    10321 caaaatacct tcactgatat gatgaaggtt ggtttggaaa ccttgattgc agaataatta
    10381 tagccaaaaa ggaagccctt tatgaattgt aggacttcct tttcttatcc agaaattgat
    10441 ctagctctct ctgatttcga agaatagtga ctttatgtga atattcttgg caaagttttt
    10501 ggtaattttc tttttgagtt ttgctacgcc catcccaaag aatccatctg ataaactccc
    10561 agtcaaagcg ttcagggcaa tctgccgcca tactttctct gacttttcca cggtatttaa
    10621 gataacgctt aaaggttcta aagagacagg tcaatggcga aaaattgaga aagatgattt
    10681 ggtcagcttc ttgcattcgt tcttggtagc agcaccaaga ataattacca tcgatgaccc
    10741 aagctttatg cttggtgaga aagtttttta tatcggttaa catccattcg tggtcactgt
    10801 cttgccaacc aggttgaaat tggagtgtgt ccatgtgcag ttttggaatg gagtagtagt
    10861 tagataactt ttctgctaga gttgacttac cagaaccaga atatccgata at
//
LOCUS       DAVKEV010000053        10754 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVKEV010000053 DAVKEV010000000
VERSION     DAVKEV010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10754
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.053"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(113..1537)
                     /locus_tag="VWZ68_001794"
     CDS             complement(113..1537)
                     /locus_tag="VWZ68_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU9372782.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVAEKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2082..4361)
                     /gene="pulA"
                     /locus_tag="VWZ68_001795"
     CDS             complement(2082..4361)
                     /gene="pulA"
                     /locus_tag="VWZ68_001795"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEU9372783.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPYGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4473..6431)
                     /gene="ligA"
                     /locus_tag="VWZ68_001796"
     CDS             complement(4473..6431)
                     /gene="ligA"
                     /locus_tag="VWZ68_001796"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEU9372784.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERGNLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6524..7702)
                     /locus_tag="VWZ68_001797"
     CDS             complement(6524..7702)
                     /locus_tag="VWZ68_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9372785.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGFIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSIHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7782..8645)
                     /locus_tag="VWZ68_001798"
     CDS             complement(7782..8645)
                     /locus_tag="VWZ68_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU9372786.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYFFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8648..10549)
                     /locus_tag="VWZ68_001799"
     CDS             complement(8648..10549)
                     /locus_tag="VWZ68_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9372787.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGDELDKLMSDYDHLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSKKTSGNVVLTVENTAI
                     GYDGEVLSQPINVDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYIEKRATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3230 a         2368 c         1909 g         3247 t
ORIGIN      
        1 ctattctagt ttcaatatac tataatacca aaaagttcgt attttttcta taattattat
       61 tattttatag caaaaaaata aaaccaggaa aacaatttcc tgattttaca cgttatttca
      121 catcaaaaac aatggatttg acatttgtca tcgcttcaat gctatattta attccttgca
      181 ctccagctcc agaacctttg acaccaagga atgggaaatt atctggacca cgctgggttt
      241 tattattaat gtggactgta cctacttcaa gtttttcagc aatttcaaag gcttttttga
      301 aatcatttgt aaagactgat gattgaaggc cgaattcaga ttcgttggca aaggcaatag
      361 cttcctctac actagccaca cgaatgattg gtaaaacagg accaaatggc tcttcccatg
      421 ccactttcat atcttttgta acttggtcaa aaagcactgg ccagaggaga ttgccctcac
      481 gtttgattgg tgtaagagcc tgagcctctt tttcttgtgc atcctcaatc aagccccaaa
      541 tgaagtcggc tgaagcattg tcaataacag gtgtaatatc agcattgtca aatggatcac
      601 caactgttaa tttagaaact tcttcctgaa gcaaagtagc taatttctct gctacacttt
      661 cgagaacaat gacacgttta atggccgtgc aacgttgtcc tgagtagcta aaggctcccg
      721 caacaatttg cttggcagca tgttccaaat ctgcatcttc tagtacaaga gctgcatctt
      781 tcccaccaag ttccaacatg ataggacgca taccagctaa acgaccaata cgttctccaa
      841 taggagttga acctgtaaag ttgatgaagt tgacttcttt gtgctcaatg atataatccc
      901 caatttctga accacgacct gtaatggtgt tgaaaacacc tgccggaatc cctgcttctt
      961 caaatgcttt agccaacaag agtccagaaa tggaaccttg tgttggtggc ttaaacatga
     1021 ccacattccc tgcaatcaag gcaggtgcaa ttttagaagc agataaatta actggataat
     1081 taaagggagc aatcgctagc acgataccaa ctggttcacg acggacaaca gccagtttgt
     1141 ttttacttgc tgcctcaaaa ccaccacctt ccattgcttg tccagtgata cggagacctt
     1201 cctcagcagc ataacgaatc aagtctgctg tacgcactac ttctccaatt gctgctttaa
     1261 tcccttttgc tacttctttg gcaaggatag taccaatttc ttccttatcg cgttctaaaa
     1321 tagctgctgt tttatgtaaa taagccgcac gttcaactgc tgataaagct cgccatgctg
     1381 gcagggctgc acgcgcagct tgcatagcct catcagcttc agtctgagtc atggctggaa
     1441 ctgtacccaa ttcttcttga ttgattggtg aataaatcgt aatttcttgt tcagatgatt
     1501 tccattttcc atttactaaa ttctgatatc ttgtcaaatt cttgtcctcc tgaaaatgat
     1561 taagatatat tttaccaaat tttcagaaaa tcacaaccct ttttgcaaaa tttttgagat
     1621 tattttcaca aacttgattt ttcaaagtat actcaataaa aataaaaaaa atccactacg
     1681 tcaaggcgag gctaatgtgg tttgaagaaa ttttcgaaga gcgtgaatga gtatcatcta
     1741 tagtaaaata aaaaaactga acaatttggt tggggacagc caaaccaatt tctcacaatg
     1801 tttcagaaac aagggtgtgc tactccaatt tcagcctact ataactgtca tagattgctg
     1861 aaacaaagtc taggtaaaag tcttcataat aaaaagacct cctatcaagt gttcaaaaac
     1921 tttgatagga ggtcttgttt tgtgaaaata tttatcaaat tttctataca agtgagctgt
     1981 tagccaggtt ctttctattc tttcaatttc aatgaatgga ttttttacta atactcataa
     2041 ctgggaattt gtctgtgtaa aaatagcgag atagatggta tttataaaac actcaagaca
     2101 gctagactaa tatcatttaa aacattatct tcttttgagc gactgttggt taccaacata
     2161 gctaaatttc ctgcattttc aaattgatag ggttctgatt tagcattcac aaccaccaag
     2221 aggtgttctt tgccgtgaac ttcatagata aggtagccgc tatgttcaat cgcagaatgc
     2281 acaaagacat gatggtaaat ttcatcatag ctagagtaag aaaaggcacc agtttttgtc
     2341 ttcaatcgga tgacttgacg gataaactca atactgtctt gacgctcatt aatcaagttc
     2401 cagttcactt ggttcacact gtcaggagca ttatagctat tcatcgcacg ctctctatca
     2461 tcatgggtca actcaccatt ttcaccagtc gcaaccagtt tggtacgacc aaattcttga
     2521 ccgatttcca taaaggccat cccctgcatg agcagattca tggctgtggc agtttcgacc
     2581 ttgcgcatga tttgctctga actttggtct ggatgaaggg ttgccaataa atcgtgaaga
     2641 ttgtaattgt catgggcttc tacatagtta agcacctgat ttggatgtgt atagcttcct
     2701 aattcacgac ttcctaggat tgctttagct agaattggct ctgtcgcagc accactgaca
     2761 aaacctgact tgatagcacc ataaacttct ccccctttga cagcatcgcg ctgattgtca
     2821 ttaaagaaac caatatttgg catctggtag gcattgtcct tcttggcctt atcataaggg
     2881 gcaagacctg ttcccatatc ccatccttct ccatagagga taatgttgga gtcgatttca
     2941 tccaagcttt gacgaatcat ctgcatggtc ttgacatcat gaatccccat caagtcaaaa
     3001 cggaagccgt caatattata ttcctgcacc cagtatagaa gagaatcaat catatacttg
     3061 cgaaacattt cgtgttcact ggctgtttca tttccaacac ccgttccatt ctggaaggta
     3121 ccatatggat tcatacgata atagtaatca gggactgttg tttggaatgg tgcatcaaca
     3181 actgagaagg tatggttata gactacatcc ataatgactc caatacccgc atcgtgataa
     3241 gcttgaacca tcaccttcaa atcacgaatg acctgagctg gatcatctgg attagttgaa
     3301 aaactagttt ctggcgcgtt atagttttgt ggatcataac cccagttgta ggttacattt
     3361 ccatcctcat cgtattcttt atgacggtct gcaattggtt gcaattgaac ataattgtag
     3421 cccagcttct tgatgtaatc aaaagcagtt gactggccgt attggttaac tgttccagcc
     3481 tgagcagcac ccaagaaagt tcctcgaaga tgttcatcta cacccgatgt aggtgattta
     3541 gtcaaatcac gaatatgcat ttcacagata actgccttac atggattttc caagcgccaa
     3601 gtagcctccg aaccgtgctt aacctcgaag ttttcaactt gcttttctac atggctcaga
     3661 atagctgaac gtttgccatc agggctggtc gcgattgtat aaggatcacg tgtcagtgtt
     3721 tggtgatgag ggaattggac ttgatactga taagccttac ctaccaaatc ttcctcaaca
     3781 tccaaactcc agacaccgat tgtattgtcc ttatgattat aagagtagct attgcctctt
     3841 ttcatctcaa aagtcttcca aacgggtgca tcattagcag ctgattcata aacgacaact
     3901 tgcacttctg tcgctgtagg tgaccagagg gaaaaatgag cctgattgtc ctctacacgg
     3961 caacccaatt ctccttggta accccaatga tggtcaaaac tagcactgtt aatggcctta
     4021 tcaaaggcaa aaggattttg atttttatag aaaggactgg caatagcagg attttcagag
     4081 taataaatcc tatcatcgcc ttccaaaatc cagacctctg ttaatagggg atagtgatta
     4141 aaacggatag aatattcttt actagtttga cctgtatgaa ccacaaaatt caagctttct
     4201 ataacatgtg aacttgggtg ttcaaagcta aataaagctc caaaataatc ttctttgtag
     4261 gttagcaaat caattcgttg atcctgactt tttacaaagg agcaagtgtc atattctcca
     4321 ttcttacgat ggtaatgaat gcgcataggg tagttataca ttttttattt ttccttttta
     4381 ctttgtttct atttcactaa taaatttttg tcaatctcgt ctcaattaac agacatagtc
     4441 atattctcta aactctgttt ttaaacgatc cattacaaac tttctagcca tgcctcatct
     4501 ctgacctgga taccaagttc ttgtgctttt tgcagtttac ttccagcgtc tgcacctacc
     4561 acgacgaggt cggtcttttt agaaacacta cctgtcactt tggcacccag actttcgagt
     4621 ttacttttag cttctgagcg cttgagtcgt tccaattttc ctgtcaatac cacggtcaaa
     4681 cctgacaagg ccgcatccgc tactaccgtc tgtcctttat agtccagatt gaccccagtt
     4741 tctttcaatt ctctgagcag aatttcagag ccttctgtcg caaaataagt ctgaagactt
     4801 ttggcaatca cgccacctag actttcaata ctagccactt cctctgaatc tgcctgatac
     4861 agattttcaa ttgaatggaa atattgaagt aaaagctgac tagccttgct tccgacatga
     4921 cgaattccca aaccaaataa gagcttctcg gcagaatttt cctttgatgc ttggatagcc
     4981 tgatacagtt tagcagcgga cttttcctta accccctcta aaaggaggaa atcctcttct
     5041 tgcaaacgat aaatatccgc cacatccttg actaaattag cagcaaaaag cttctcaaca
     5101 atagatggac caaggcctgt aatattcata gcatcacgag aagcaaagtg aatcaagcct
     5161 tccatgattt gagcagggca acgcggattg atacaacgta gggccacttc atcttcaaag
     5221 tgcaacaagt cagagttaca acttggacag tttgtaggga tatctagttt ttcttcagaa
     5281 acccgtttgg actctaccac acgtaaaacg gcagggatga tgtcaccagc cttatataca
     5341 atgaccgtat cgtcttttcg gatatctttt tcagcaatat aatctacatt gtgcagggtc
     5401 gcacggctaa cagtcgtacc ggcaagttgt actggtgtta gattagcagt tggagttaca
     5461 acaccggtac ggccaactgt ccagtcaact gataagagtt gagcttcttt ttcttcagca
     5521 gggaacttgt aggctactgc ccactttgga gccttaacgg taaaaccaag ttcttcttga
     5581 cttgctaggt cgttgacctt gattaccact ccatcaatat cgtaaggcag atttccccgt
     5641 tcctgtccta cttcttggat aaaattccag atttcatcta tgttttcagc caagattcgc
     5701 ttaggattga ccacaaaacc tagttgttct aggtacttca aacccttttc ttggctatca
     5761 cgagttgaag ggctggcttc ttgatagaga aacgttgcaa gattacgctt ggcaactact
     5821 gctgtatcca actgacgcag agttcctgct gccgcattac gaggattagc aaattcaggc
     5881 tctccatttt cttggcgcac ttggttaact tggtcaaagg aagcgcgtgg catgtaacat
     5941 tccccacgaa ctgtgatatc tagttcttct ggcaaagtca aagggatgtc cttaacacgc
     6001 ttgaggtttt ctgtgatatt ttcaccaatt gaaccatctc cacgtgttac cccagcaacc
     6061 aaaatcccct tttcataagt cagcgagata gataagccat cgattttcag ctcacaaata
     6121 taggtcggat gagccacttc cttacgaaca cgcgcatcaa aagcatctag ctcctcacgt
     6181 gaaaaagcat cctgcaaact ataaagagga tactgatgac tgtatttttc aaaaccatct
     6241 aaaaccttgc caccaacacg atgagtcgga ctgtctgcta gcacttgctc tggataagca
     6301 gtttctaact cgaccaactc acggtaaagg cggtcatact cactgtctga aaccgaggga
     6361 ttatcgctgg tatagtactc agtcgcatag cgattgagca aagcgactaa ctcattcatt
     6421 cttttattca taagaccatt ttaccataaa acaagccctc ctcacaaacg agaagggcgg
     6481 aaaaaacact tagtttgaaa ttatttttga aactcaagca accttatatc aatttttcaa
     6541 aatgagttcg aacataaata aacgatatac aagacaagat gataacacca cttccaatta
     6601 tcaggaaaga agagagatgt atacttggca agactgtcat aaatcctttt gcaataggca
     6661 taaatagaat agctaaggta aaaattgtac tcagtactct tccaagaaat tcgctctcaa
     6721 ccttggtttg tacttgagta aaaaagtgaa tattaaaaat cgtcataaac aattcacaaa
     6781 ctaaatttcc agaaaaggaa agaaaagttg gaagtggtaa tcccatcata aaaactccga
     6841 cacctgtcaa agccagtaaa atcaaaagat tataaatatt agctttaatt ttactagcta
     6901 gaagagcccc aatgatgaaa ccaatagccc ccatagttaa aatacttgca taggctcctt
     6961 ctgacccgta aagctgattc gaaaagggaa gtagaaattc aaaagctgca aaaaagaaat
     7021 taacgctgga agctaccagc aaaaggaaga aaatttcttg ctgatgccag atatagtgta
     7081 acccatcctt gatatctaca aaaatatctc tcccagtaaa agcctttttc tcttgaactt
     7141 ttgcttcctc ttttggaagg aaagccacta gaacaaaagc aatgaaaaaa gtcagcgagt
     7201 ctagcagtag cgtcatatgg agacttgcaa actgtaaaac aaggaaggaa agaacaggag
     7261 agctaacacc tacaacctgc aaaaccagct ctaagcgaga attatagatc acaatctcat
     7321 ctttctccac cacttcagtt atgatagctt tattggctgt gcgagaaaag gcaaaagcaa
     7381 tagcctgcac aatgttagca acaatcaaag cgccaatcat ccagctatca ttccttatga
     7441 aagaaatagc cagacaaaga atcccacaaa caagatctgc cgtcattaaa atcttacgac
     7501 gagaaaaacg gtctgaaata actccgccaa agggattgac gagaatagat gtgacgagct
     7561 cagaaatctg atacattcct aaaactgtct gtcctatagt ccccatagaa gccaaccaga
     7621 cactatttcc ataatcatag agcatatttc ccattttatt gatagcccca cggctaatca
     7681 actgcactgc atagcgattc atattaaagc tcctctcaaa ttttgaaact attgtatcaa
     7741 aaccgaaagg agctttttat tttttccctt atttgggaaa attaactttt gacaaatttt
     7801 tcgtagtgtt cctgataata ggctacttgc tctggaagac ctaacacatc aaaaatatgt
     7861 atggcctctt gcatctgctt acagccttct ttacactgtc ctttttgata taaggcaaaa
     7921 ccttttaaat aatggaaaac attacgctca taaagcttaa tacctttgtc aataatcttc
     7981 tctgtataag cctcaaaata gttggcatta taaaaagaag aatgctctaa acaatgctgg
     8041 taacaattga gggccaaaat caaaactaat ctcttatggc gactaatctc ttggtaaaat
     8101 tcctccctct ccataacttc tctaccaatc cgagtgacat agtctacatc gtagaaacta
     8161 tagaggttac cgaaaagaat caactcatac atggtccatt cttctgtttt gaagaaataa
     8221 tctgctacct tatccaaatc atcctgcttc atatcataac tcgcatctct ttgacaaatc
     8281 agaccttgta gcaaaatcca gttcagctca aaataaaggg gagtcgtcga actcttagac
     8341 ttttcaagtt gttctctttg aagcttttga aaacctgcaa tatcgtttga atagtaaagt
     8401 gggataatct gtgccatcat agacacatgt tcatgattat gaaaattcct tgccttatcc
     8461 atgaaatttt cgattgttac atgaatgtta tccaaaatct caaagaaacg ggagactgcc
     8521 aggtcagact ccccaagctc aaagcgagat aactgagagg tagagcagga ttcgcctgct
     8581 gcttccttta aagaataatt tccacttgtt cgaaattcac gaaatacttt tccaagatgt
     8641 tccatcttta cacctgatct gataattctt cccactcaag catagcttct tcctgacgat
     8701 ggctgatttt gtccagctca gcctgtaatt ccatgagttt gtcggcatcg tttgtttcca
     8761 acatttgttc agaaatggct tggctttgac tttctagctc ttcaatttca gcttctagac
     8821 tttcgatttg tcgcatgagt ttgcgaactt ctttttgact ttctttctgg gcctgatagt
     8881 cattgactgg acttgcttcc tttgcttgat tgctagttga agcttcctca gtctgactca
     8941 tttctgctgt tgctctcttc tcaatatagt agtcgtaatc tccaaggtag agagttgaac
     9001 cattctcaga caattccaaa acatgagttg ccacacgatt gataaagtaa cgatcatgac
     9061 tgacaaaaag caaggtacca tcaaagtcaa tcaaggcatt ttctagcact tccttactat
     9121 caatatccaa gtggttggtc ggctcatcca gaatcaaaaa gttattgttt tccatagaca
     9181 atttagctaa aagcaaacga gctttttcgc caccagatag catgccgact gattttttaa
     9241 catcatctcc tgagaaaagg aaggctccaa gacggttgcg gatttcaact tctggtgtca
     9301 gtttgaaatc attccagagt tcatccagca ccgtattact tggtgtcagc ttgctttggg
     9361 tttggtcata gtaaccaacc tcaacattag cgccaaagcg cttttctccc ttgataaaag
     9421 gaatctggtc cacaatagac ttgataaagg ttgacttgcc gataccattt ggaccaacga
     9481 tagcgacagc attcatctta cgaagatcta cgttaatcgg ttgtgacagg acttccccgt
     9541 cataaccaat agcagtattt tcaacagtca aaacaacatt gcccgacgtt tttttagact
     9601 ggaaggtcat gttggctgct ttcttgccag cttcaggctt gtccaaacgc tccatttttt
     9661 ctagttgttt acggcgagat tgagcacgtt tagtcgttga agcacgaact agattgcgat
     9721 tgacaaagtc ttccagagca gcgatttcct tctgttgctt ttcatagttt tttgcctcag
     9781 tagctagctt ttgctccttc aattcgacaa aacgagagta attccccaca tagcgatcca
     9841 aggaatgctt ggtcaaatct agcgtaattg tcgcaacctt gtccaagaaa taacggtcgt
     9901 ggctgacgat aatgagggca ccgctatagt ttaccaagta attctctagc caggcgatgg
     9961 tttcaatatc caagtggtta gttggctcgt ccaagaccaa gagattgggc ttttcaagga
    10021 gcattttagc tagagccaaa cgagtatttt gaccacctga aagttcagct attttcatct
    10081 gccacataga ctcgtcaaac ttgaatccat tcaaaatcgc tcgaatatca gcttcatagg
    10141 taaagccgcc tgcttggcga aaattctcag ataagtggtc gtaatctgac atcagtttat
    10201 ccaattcatc gccagacttt tcacccatct ccaactccat ctgacgaagt tgtttatctg
    10261 tccgacgtaa gtcatcaaag acatgaagca tctcatcata gatggtattt tcagactcaa
    10321 aacggctatc ttgagctagg taagacagag aaatatcttt tttcttattg atttctccac
    10381 tagttggctc ctcttctcca actaaaatct tcaaaagagt agacttacct gcaccatttt
    10441 tcccaacaag ggcaatccga tctcgttcat caacctgcag gttgatatta tcgaaaagaa
    10501 cctctcctgc aaaagaacgt tcaattttat tagcttgtaa aataatcata caagtagtat
    10561 agcatgtttc cctaagtcat tcaagataat cgtaagtctt ttagtacaac ttttataaca
    10621 taaaataaac taaattatgt atattttata ttagattcct tcactatctt gttggatttt
    10681 ctaaccagct aatcttgttt caaatagtta tcgcacaagc ctattattta attcttttca
    10741 ttatttacgt acgc
//
LOCUS       DAVKEV010000054        10730 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVKEV010000054 DAVKEV010000000
VERSION     DAVKEV010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10730
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.054"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(73..165)
                     /locus_tag="VWZ68_001800"
                     /pseudo
     CDS             complement(73..165)
                     /locus_tag="VWZ68_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(201..484)
                     /locus_tag="VWZ68_001801"
                     /pseudo
     CDS             complement(201..484)
                     /locus_tag="VWZ68_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(474..614)
                     /locus_tag="VWZ68_001802"
     CDS             complement(474..614)
                     /locus_tag="VWZ68_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEU9372788.1"
                     /translation="MVSCHSSLRSYIAEPILKQAGFTVQNLDGAYSLYKMVNPEGVEY
                     GN"
     gene            706..1470
                     /locus_tag="VWZ68_001803"
     CDS             706..1470
                     /locus_tag="VWZ68_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEU9372789.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            2035..3414
                     /locus_tag="VWZ68_001804"
     CDS             2035..3414
                     /locus_tag="VWZ68_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU9372790.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            3428..4093
                     /locus_tag="VWZ68_001805"
     CDS             3428..4093
                     /locus_tag="VWZ68_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEU9372791.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            4228..4302
                     /locus_tag="VWZ68_001806"
                     /pseudo
     CDS             4228..4302
                     /locus_tag="VWZ68_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            4448..4987
                     /locus_tag="VWZ68_001807"
     CDS             4448..4987
                     /locus_tag="VWZ68_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9372792.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            5054..5464
                     /locus_tag="VWZ68_001808"
     CDS             5054..5464
                     /locus_tag="VWZ68_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU9372793.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            5580..7697
                     /locus_tag="VWZ68_001809"
     CDS             5580..7697
                     /locus_tag="VWZ68_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEU9372794.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLGENVKTKGQYFYQVALD
                     GNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLDNIVATKKVTININGLISK
                     ETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVNHVIPYELFAGDGMLTRLLLKAS
                     DKAPWSDNGDAKNPALSPLGENVKTKGQYFYQLALDGNVAGKEKQALIDQFRANGTQT
                     YSATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHN
                     HATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASI
                     GFLGLALAGLLGGLGLKNKKEEN"
     gene            7864..8562
                     /locus_tag="VWZ68_001810"
     CDS             7864..8562
                     /locus_tag="VWZ68_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9372795.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEAYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQI"
     gene            8559..9611
                     /locus_tag="VWZ68_001811"
     CDS             8559..9611
                     /locus_tag="VWZ68_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU9372796.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            9806..10417
                     /gene="rpsD"
                     /locus_tag="VWZ68_001812"
     CDS             9806..10417
                     /gene="rpsD"
                     /locus_tag="VWZ68_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEU9372797.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            10602..>10730
                     /locus_tag="VWZ68_001813"
     CDS             10602..>10730
                     /locus_tag="VWZ68_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9372798.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKE"
BASE COUNT         3088 a         2089 c         2425 g         3128 t
ORIGIN      
        1 aaaacagtgt tttgagctga cttcgtcagt tccatccaca accttaaaac agtgttttga
       61 gctgacttcg tcagttccat ccacaacctt aaaacagtgt tttgagcagc ctgcggctaa
      121 cttcctagtt tgcactttaa ttttcattga gtattacttc atcttctcat gaaattgagt
      181 ttttgcccag ctcctcttga ttattctact tgaccgggcc aagcattcat accaccttct
      241 acgttggtaa cggtgaggcc ttgggagctg agaaattggc aggtagatgc agagcggact
      301 cctccgtgac aaatgacata gtattcatgg tcaggtttga gttctttgta gccttgctct
      361 aaggtattta tggaagattt ttgggtcctg cttggaattc atgtgcttca cggacatcga
      421 taagttccag attttcattt tgatattttc tataaaagtc agccatgctg atactagttt
      481 ccatattcta ctccttctgg gttaaccatt ttgtatagtg aataagcgcc gtcaaggttt
      541 tggacggtaa atcctgcttg cttgaggata ggctctgcga tatagctgcg caaactactg
      601 tggcaactga cgatgtaggc ttgtttttct cctcagttca tcagcttcct ccttgacact
      661 cggtcagatt ttgatacaat agtacaaaat tagaggaggt gggctatgat tcagaaacat
      721 gcgattccca ttttagagtt tgatgataat cctcaggcgg ttatcatgcc caatcacgag
      781 gggttggatt tgcagttgcc aaagaagtgt gtctatgctt ttttaggtga ggagattgac
      841 cgctatgcga gggaagtagg ggcgaactgt gttggcgaat tcgtttctgc taccaagacc
      901 tatccagtct atgtcatcaa ctacaagggt gaggaggtct gtctggctca ggctcctgtt
      961 ggctccgctc cagcagccca gtttatggat tggttgattg gctatggtgt ggagcagatt
     1021 atctctactg ggacctgtgg tgtcctagct gatatagagg aaaatgcctt tctagtccct
     1081 gttcgcgctc tgcgagatga aggagccagt taccactatg tggcaccttc tcgttatatg
     1141 gaaatgcagc cagaggctat tgctgccatt gagcgagttt tggatgatag agggattcct
     1201 tatgaagaag tcatgacctg gtccacagat ggtttttacc gagaaacggc tgaaaaggtg
     1261 gcttatcgta aggaagaagg ctgtgctgtt gtggagatgg agtgttctgc tcttgcggca
     1321 gtagctcaat tgcgtggagt tctctggggt gaattgttgt tcacagcaga ttctctagcg
     1381 gacttggacc agtacgacag tcgtgactgg ggctcggaag cttttaataa ggcactagaa
     1441 ctgagtttag caagtgttca ccacctttag ttgtactggc aaaggatttg ttttatcata
     1501 aaatgtctag ctcatacttt tcaaaaatat gtttaaacga ggtcaccttc ctcttgtcct
     1561 aggcatgttg aggttgggaa aaatctttaa aatcagaaaa acgtatcata tcaggtgatg
     1621 aaaattttga tactatgcgt tttatgttgg taagatttag agtgagatga aatgatactc
     1681 ttcgaaaatc tcttcaaacc aggtcagctt caccttgccg tatagatgtt actgacttcg
     1741 tcagttctat ccacaacctc aaaacagtgt tttgagcaac ctgtgactag ctttctaagc
     1801 gatgccttgg ttctcattgc ctataatcaa aaagagaaat tttctcctga aaagcatata
     1861 gagtagctgg cgttaaaagc tcctgtcttg cttttttgac ctatagtcac atctatcaag
     1921 tattgttctt gcctaagcta tcaataaaaa ggtggcattt tttaggcttg gtgttagtag
     1981 attttgcctt atcctatcta agtcatttcg aactttttat ggtacaatgg aaacatgtta
     2041 ttcaaattat ctaaggaaaa aatagagcta ggcttatctc gtttatcgcc agcccgtcgt
     2101 atttttttga gttttgcctt ggtcatttta ctaggctctc ttcttttgag cttgcccttt
     2161 gtccaagttg aaagctcacg agcgacttat tttgatcatc ttttcactgc tgtctctgca
     2221 gtctgtgtga caggtctctc aacccttcca gtagctcaca cctataatat ctggggccaa
     2281 ataatctgtt tgctcttgat tcagatcggt ggtctagggc tcatgacctt tattggggtt
     2341 ttctatatcc agagcaagca aaagcttagt cttcgtagcc gtgcaactat tcaggatagt
     2401 tttagttatg gagaaactcg atctttgaga aagtttgtct attctatttt tctcacgacc
     2461 tttttggttg agagcttggg agctattttg cttagttttc gccttattcc tcaacttggc
     2521 tggggacgtg gtctttttag ttccattttt ctagcgatct cagccttctg taatgccggt
     2581 tttgataatt tagggagcac cagtttattt gcttttcaga ccgatttact ggtcaatctg
     2641 gtgattgcag gcttgattat tacaggcggc cttggtttta tggtctggtt tgatttggct
     2701 ggtcatgtag gaagaaagaa aaaaggacgt ctgcactttc atacgaagct tgtactatta
     2761 ttgactatag gtttgttgtt atttggaaca gcaactactc tctttcttga gtggaacaat
     2821 gctggaacga ttggcaatct ccctgttgcc gataaggttt tagttagctt ttttcaaaca
     2881 gtgacgatgc gaacagctgg cttttctacg atagattata ctcaggctca tcctgtgact
     2941 cttttgattt atatcttaca gatgtttcta ggtggggcac ctggaggaac agctggggga
     3001 ctcaagatta cgacattttt tgtcctcttg gtctttgcac gaagtgagct tctaggcttg
     3061 cctcatgcca atgttgcgag acgaacgatc gcgccgcgaa cggttcaaaa atcctttagt
     3121 gtctttatta tctttttgat gagcttcttg ataggattga ttctgctagg gataacagcc
     3181 aaaggcaatc ctccctttat ccacctcgta tttgaaacca tttcagctct tagtacagtt
     3241 ggtgtaacgg caaatctgac tcctgacctt gggaaattgg ctctcagtgt tatcatgcca
     3301 cttatgttta tgggacgaat tggtcccttg accttgtttg ttagcttggc agattaccat
     3361 ccagaaaaga aagatatgat tcactatatg aaagcagata ttagtattgg ttaagaaagg
     3421 aaagagcatg tcagatcgta cgattggaat tttgggcttg ggaatttttg ggagcagtgt
     3481 cctagctgcc ctagccaagc aggatatgaa tattatcgct attgatgacc acgcagagcg
     3541 catcaatcag tttgagccag ttttggcgcg tggagtgatt ggtgacatca cagatgaaga
     3601 attattgaga tcagcaggga ttgatacctg cgataccgtt gtagtcgcga caggtgaaaa
     3661 tctggagtcg agtgtgcttg cggttatgca ctgtaagagt ttgggggtac cgactgttat
     3721 tgctaaggtc aaaagtcaga ccgctaagaa agtgctagaa aagattggag ctgactcggt
     3781 tatctcgcca gagtatgaaa tggggcagtc tctagcacag accattcttt tccataatag
     3841 tgttgatgtc tttcagttgg ataaaaatgt gtctatcgtg gagatgaaaa ttcctcagtc
     3901 ttgggcaggt caaagtctga gtaaattaga cctccgtggc aaatacaatc tgaatatttt
     3961 gggtttccga gagcaggaaa attccccatt ggatgttgaa tttggaccag atgacctctt
     4021 gaaagcagat acctatattt tggcagtcat caacaaccag tatttggata ccctagtagc
     4081 attgaattcg taaagaggga tgacccctct tttttgatgc ctaagatggc aaatagagac
     4141 agaagcccct tgtcttctag taaaagttct tcaaaggctg gactttatgg taaaatagaa
     4201 agaagtgaca agagagagta atactcaatg aaaatcaaag atcaaactag gaaactagct
     4261 acgggctgct caaaacactg ttttgaggtt gcagatagaa ctgacgaagt cagctcaaaa
     4321 cactgttttg aggttgcaga tagaactgac gaagtcagta acatctatac ggcaaggcga
     4381 cgttgacgcg gtttgaagag attttcgaag agtataagaa aaaatcagtc ccctaaagga
     4441 gtagattatg aagttattgt ctatcgcaat ttctagctat aatgcagcag cctatcttca
     4501 ttactgtgtg gagtcgctag tgattggtgg tgagcaagtt gggattttga ttatcaatga
     4561 cgggtctcag gatcagactc aggaaatcgc tgagtgttta gctagcaagt atcctaatat
     4621 cgttagagcc atctatcagg aaaataaatg ccatggcggt gcggtcaatc gtggcttggc
     4681 agaggcttct gggcgctatt ttaaagtagt tgacagtgat gactgggtgg atcctcgtgc
     4741 ctacttgaaa attcttgaaa ccttgcagga acttgagagc aaaggtcaag aggtggatgt
     4801 ctttgtgacc aattttgtct atgaaaagga agggcagtct cgtaagaaga gtatgagtta
     4861 cgattcagtc ttgcctgttc ggcagatttt tggctgggac caggtcggaa atttctccaa
     4921 aggccagtat accatgatgc actcgctgat ttatcggaca gatttgttgc gtgctagcca
     4981 gttctaactg cctgaacata ctttttatgt cgataatctc tttgtcttta cgccccttca
     5041 gcaggtcaag accatgtact atctgcctgt cgatttctat cgttatttga ttgggcgtga
     5101 ggaccagtct gtcaatgagc aagtgatgat taagtgcatt gaccagcaac tcaaggtcaa
     5161 tcgactcttg atagaccaac ttgatttgtc ccaagtgagt catcccaaaa tgcgagaata
     5221 tctgctgaat catattgaac tcacgacggt gatttccagt accctgctca accgatctgg
     5281 aacagcggag catctggcaa aaaaacgcca attgtggacc tatattcagc agaaaaatcc
     5341 agaagtcttt caggctattc gtaagaccat gttgagccgt ttgaccaaac attctgtctt
     5401 gccagatcgc aaactgtcca atgtcgtcta tcaaatcacc aaatctgttt atggatttaa
     5461 ttaatataag tgttttataa gagggattta agaaaaattt taactttttc ttagtccttt
     5521 ttaatttcag gagattatac tagagtcatc aaataaagaa agactctaag gagaatccta
     5581 tgaaattcaa tccaaatcaa agatatactc gttggtctat tcgccgtctc agtgtcggtg
     5641 ttgcctcagt tgttgtggct agtggcttct ttgtcctagt tggtcagcca agttctgtac
     5701 gtgccgatgt ggtcaatccg accccaggtc aagtcttacc tgaagagaca tcgggaacga
     5761 aagagggtga cttatcagaa aaaccaggag acaccgttct cactcaagcg aaacctgagg
     5821 gcgttactgg aaatacgaat tcacttccga cacctacaga aagaactgaa gtgagcgagg
     5881 aaacaaactc ttctagtctg gatacacttt ttgaaaaaga tgaagaagct caaaaaaatc
     5941 cagagctaac agatgtctta aaagaaactg tagatacagc tgatgtggat gggacacaag
     6001 caagtccagc agaaactact cctgaacaag taaaaggtgg agtgaaagaa aatacaaaag
     6061 acagcatcga tgttcctgct gcttatcttg aaaaagctga agggaaaggt cctttcactg
     6121 ccggtgtaaa ccaagtaatt ccttatgaac tattcgctgg tgatggtatg ttaactcgtc
     6181 tattactaaa agcttcggat aatgctcctt ggtctgacaa tggtactgct aaaaatcctg
     6241 ctttacctcc tcttgaagga ttaacaaaag ggaaatactt ctatgaagta gacttaaatg
     6301 gcaatactgt tggtaaacaa ggtcaagctt taattgatca acttcgcgct aatggtactc
     6361 aaacttataa agctactgtt aaagtttacg gaaataaaga cggtaaagct gacttgacta
     6421 atctagttgc tactaaaaat gtagacatca acatcaatgg attagttgct aaagaaacag
     6481 ttcaaaaagc cgttgcagac aacgttaaag acagtatcga tgttccagca gcctacctag
     6541 aaaaagccaa gggtgaaggt ccattcacag caggtgtcaa ccatgtgatt ccatacgaac
     6601 tcttcgcagg tgatggtatg ttgactcgtc tcttgctcaa ggcatctgac aaggcaccat
     6661 ggtcagataa cggcgacgct aaaaacccag ccctatctcc actaggtgaa aacgtgaaga
     6721 ccaaaggtca atacttctat caagtagcct tggacggaaa tgtagctggc aaagaaaaac
     6781 aagcgctcat tgaccagttc cgagcaaacg gtactcaaac ttacagcgct acagtcaatg
     6841 tctatggtaa caaagacggt aaaccagatt tggacaacat cgtagcaact aaaaaagtca
     6901 ctattaacat aaacggttta atttctaaag aaacagttca aaaagccgtt gcagacaacg
     6961 ttaaagacag tatcgatgtt ccagcagcct acctagaaaa agccaagggt gaaggtccat
     7021 tcacagcagg tgtcaaccat gtgattccat acgaactctt cgcaggtgat ggcatgttga
     7081 ctcgtctctt gctcaaggca tctgacaagg caccatggtc agataacggc gacgctaaaa
     7141 acccagctct atctccacta ggtgaaaacg tgaagaccaa aggtcaatac ttctatcaat
     7201 tagccttgga cggaaatgta gctggcaaag aaaaacaagc gctcattgac cagttccgag
     7261 caaatggtac tcaaacttac agcgctacag tcaatgtcta tggtaacaaa gacggtaaac
     7321 cagatttgga caacatcgta gcaactaaaa aagtcactat taagataaat gttaaagaaa
     7381 catcagacac agcaaatggt tcattatcac cttctaactc tggttctggc gtgactccga
     7441 tgaatcacaa tcatgctaca ggtactacag atagcatgcc tgctgacacc atgacaagtt
     7501 ctaccaacac gatggcaggt gaaaacatgg ctgcttctgc taacaagatg tctgatacga
     7561 tgatgtcaga ggataaagct atgctaccaa atactggtga gactcaaaca tcaatggcaa
     7621 gtattggttt ccttgggctt gcgcttgcag gtttactcgg tggtctaggt ttgaaaaaca
     7681 aaaaagaaga aaactaatca gctaaggaaa taaatgatgg atagtgggct gactaagatt
     7741 agtttaacaa ctcaatcagc aatcaggact ttctttcaat agcagattaa aatcatcgta
     7801 aaacaataaa aatagtgtta tacttaaagc agtatagcac tgtttttatc aaaggagaga
     7861 cagatgggaa agacaatttt actcgttgac gacgaggtag aaatcacaga tattcatcag
     7921 agatacttaa ttcaggcagg ttatcaggtc ttggtagccc atgatggact ggaagcgcta
     7981 gagctgttca agaaaaaacc gattgatttg attatcacag atgtcatgat gcctcggatg
     8041 gatggttatg atttaatcag tgaggttcaa tacttatcac cagagcagcc tttcctattt
     8101 attactgcta agaccagtga acaggacaag atttacggcc tgagcttggg agcagatgat
     8161 tttattgcta agccttttag cccacgtgag ctggttttgc gtgtccacaa tattttgcgc
     8221 cgccttcatc gtgggggcga aacagagctg atttcccttg gcaatctaaa aatgaatcat
     8281 agtagtcatg aagttcaaat aggagaagaa atgctggatt taactgttaa atcatttgaa
     8341 ttgctgtgga ttttagctag caatccagag cgagttttct ccaagacaga cctctatgaa
     8401 aagatctgga aagaagccta cgtggatgac accaatacct tgaatgtgca tatccatgct
     8461 cttcgacagg agctggcaaa atatagtagt gaccaaactc ccactattaa gacagtttgg
     8521 gggttgggat ataagataga gaaaccgaga ggacaaatat gaaactaaaa agttatattt
     8581 tggttggata tattatttca accctcttaa ccattttggt tgttttttgg gctgttcaaa
     8641 aaatgctgat tgcgaaaggc gagatttact ttttgcttgg gatgaccatc gttgccagcc
     8701 ttgtcggtgc tgggattagt ctctttctcc tattgccagt ctttacgtcg ttgggcaaac
     8761 tcaaggagca tgccaagcgg gtagcggcca aggattttcc ttcaaatttg gaggttcaag
     8821 gtcctgtaga atttcagcaa ttagggcaaa cttttaatga gatgtcccat gatttgcagg
     8881 taagctttga ttccttggaa gaaagcgaac gagaaaaggg cttgatgatt gcccagttgt
     8941 cgcatgatat taagacccct atcacttcga tccaagcgac ggtagaaggg attttggatg
     9001 ggattatcaa ggagtcggag caagctcatt atctagcaac cattggacgc cagacggaga
     9061 ggctcaataa actggttgag gagttgaatt ttttgaccct aaacacagct agaaatcagg
     9121 tggaaactac cagtaaagac agtatttttc tggacaagct cttaattgag tgcatgagtg
     9181 aatttcagtt tttgattgag caggagagaa gagatgtcca cttgcaggta atcccagagt
     9241 ctgcccggat tgagggagat tatgctaagc tttctcgtat cttggtgaat ctggtcgata
     9301 acgcttttaa atattctgct ccaggaacca agctggaagt ggtggctaag ctggagaagg
     9361 accagctttc aatcagtgtg accgatgaag ggcagggcat tgccccagag gatttggaaa
     9421 atattttcaa acgcctttat cgtgtcgaaa cttcgcgtaa catgaagaca ggtggtcatg
     9481 gattaggact tgcgattgcg cgtgaattgg cccatcaatt gggtggggaa atcacagtca
     9541 gcagccagta cggtctagga agtaccttta ccctcgttct caacctctct ggtagtgaaa
     9601 ataaagccta aaaccccttt acaaatccag ctattcatgg taaaatggat tttgtgtgaa
     9661 atatcagcag gaaagcatga agctcgtcaa caggtgtctt atgacaagta accttggctg
     9721 tttaggcgaa gggcatctgc acgaatcagg gctttctaag tgactatttc caccgaaata
     9781 ttatttatat caggaggaca ttcatatgtc acgttataca ggaccatctt ggaaacaagc
     9841 tcgtcgcctt ggcctttcac ttacaggtac aggtaaagaa ttggcacgtc gtaactacgt
     9901 accaggacaa cacggaccaa acaaccgttc taaattgtca gaatatggtt tgcaattggc
     9961 tgaaaaacaa aaacttcgtt tcacttacgg tgtaggtgaa aaacaattcc gtaacttgtt
    10021 cgtacaagct acaaaaatca aaggtggaat cctaggtttc aactttatgc ttcttttgga
    10081 acgtcgtttg gataatgttg tttaccgtct tggtctcgcg actactcgtc gtcaagctcg
    10141 tcaattcgta aaccacggtc acatccttgt tgacgggaaa cgcgttgata tcccatcata
    10201 ccgcgtaact ccaggtcaag tgatctcagt tcgtgaaaaa tcattgaaag ttccagcaat
    10261 ccttgaagca gtagaagcta ctcttggacg tccagcattc gtatcattcg acgctgaaaa
    10321 gttggaaggt tcattgactc gcttgccaga acgcgacgaa atcaacccag aaatcaacga
    10381 agcacttgtc gttgaattct acaacaagat gttgtaatat tttattgaat aagacaggct
    10441 ttgaggcctt gatattaagc actttgggac gttctccctt agtgcttttt tgatttctct
    10501 tagtatccag ctataatcgt tgagacataa ctagaccgat atagtccaaa gtgatatagt
    10561 aaaatgaacc aaaaatagta cacaatgtgg tataatcttt tatggcatat tcaatagatt
    10621 ttcgtaaaaa agttctctct tattgtgagc gaacaggtag tataacagaa gcatcacacg
    10681 ttttccaaat ctcacgtaat accatttatg gctggttaaa gctaaaagag
//
LOCUS       DAVKEV010000055        10463 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVKEV010000055 DAVKEV010000000
VERSION     DAVKEV010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10463
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.055"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(75..710)
                     /locus_tag="VWZ68_001814"
     CDS             complement(75..710)
                     /locus_tag="VWZ68_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEU9372799.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(712..1539)
                     /locus_tag="VWZ68_001815"
     CDS             complement(712..1539)
                     /locus_tag="VWZ68_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9372800.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKVRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDIIQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(1561..1896)
                     /locus_tag="VWZ68_001816"
     CDS             complement(1561..1896)
                     /locus_tag="VWZ68_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEU9372801.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(1897..2613)
                     /locus_tag="VWZ68_001817"
     CDS             complement(1897..2613)
                     /locus_tag="VWZ68_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEU9372802.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWFKQADLAIG
                     DFEETINKDHYLAGYPLFNAPAEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNGIKVALLAYSYGFNGIEQYISQEDYNRYLSD
                     LNEDKMKAEIERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHL
                     YVVEPSETIEKDGDKKLIVY"
     gene            complement(2756..2947)
                     /locus_tag="VWZ68_001818"
     CDS             complement(2756..2947)
                     /locus_tag="VWZ68_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372803.1"
                     /translation="MKEILICDIIKRKGLHKKVGRMKMQRRQNRNQGGLAFRFMKGLV
                     NFLGVIASGAIRDLWRYSC"
     gene            3136..3747
                     /locus_tag="VWZ68_001819"
     CDS             3136..3747
                     /locus_tag="VWZ68_001819"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU9372804.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEGIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            3792..4520
                     /gene="rlmB"
                     /locus_tag="VWZ68_001820"
     CDS             3792..4520
                     /gene="rlmB"
                     /locus_tag="VWZ68_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEU9372805.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKNLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENSLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(4559..5470)
                     /gene="trxB"
                     /locus_tag="VWZ68_001821"
     CDS             complement(4559..5470)
                     /gene="trxB"
                     /locus_tag="VWZ68_001821"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEU9372806.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVRKIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(5536..5760)
                     /locus_tag="VWZ68_001822"
     CDS             complement(5536..5760)
                     /locus_tag="VWZ68_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEU9372807.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(5838..6581)
                     /locus_tag="VWZ68_001823"
     CDS             complement(5838..6581)
                     /locus_tag="VWZ68_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9372808.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(6581..7381)
                     /locus_tag="VWZ68_001824"
     CDS             complement(6581..7381)
                     /locus_tag="VWZ68_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9372809.1"
                     /translation="MNVTTILASDWYQNLMQLIPNGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(7539..7895)
                     /locus_tag="VWZ68_001825"
     CDS             complement(7539..7895)
                     /locus_tag="VWZ68_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU9372810.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(7889..8419)
                     /locus_tag="VWZ68_001826"
     CDS             complement(7889..8419)
                     /locus_tag="VWZ68_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEU9372811.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRSNRRRSTC"
     gene            complement(8419..8913)
                     /locus_tag="VWZ68_001827"
     CDS             complement(8419..8913)
                     /locus_tag="VWZ68_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9372812.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            9048..9494
                     /locus_tag="VWZ68_001828"
     CDS             9048..9494
                     /locus_tag="VWZ68_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEU9372813.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            9491..10138
                     /locus_tag="VWZ68_001829"
     CDS             9491..10138
                     /locus_tag="VWZ68_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEU9372814.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILTASVLQYIAIVYYM"
BASE COUNT         3100 a         2405 c         1822 g         3136 t
ORIGIN      
        1 cgtcactttt tattttaaag gattttagaa ttttttacaa gatattatgc tcaaatttaa
       61 cattatttag ctatttagta aagatagtct ttcaaggatt ttgacaaagc ctgataacca
      121 gcaatactga ggtgcagtcc atcagttgta tattcttttt tgagttggcc tgcttggtct
      181 gtcaaacaat caaatactgg cacaaattcc acctgcatat aggcagatgc aagctcttga
      241 taggcttgat tccagttctg aattttttca ttcgagcgga tatagactgc ctgctggtac
      301 tcctctccct cattgacagg caaaatggaa agcaatttaa tctctgtcaa tggataatcg
      361 cgagcaacgg attgaatgat agcttcgaga ttattgagag cctcattcac aggaacatcc
      421 tttccgatat catttgtccc aatcagaaga aaaattttat ctactgctcc accatataga
      481 tgagcatcaa gattctctag taacagtcct gtctgatagc cacgaattcc tcgattgaca
      541 atcgtctttg aagtcccaaa tagctcctgt agaggataat actcgacaat ggaatcccca
      601 ataaaaagaa tgtttggttc tacaacagaa atgtgattta ggtgacgata cttagtttga
      661 attttttctt gttcctttag gagccaattt tctaataact gtactgccac ttcattctcc
      721 tttttctaac cagttttcca agacttgata aactcctcct tggctgttgg ctggtgctag
      781 agcagtcgcc acagctttgg ctttctcatc agcattttcc atcgcatagg caattccagc
      841 catttcaagc atttcaacat cattttcact atcaccaaaa gccatgattt cttgggattt
      901 caagtcccag cgcttgagta attcctccaa gccccatgct ttatgaatcc cagcttggat
      961 gatatcaatg caaccatagc cactggatac agctcggaca cggccatcaa agagagcatt
     1021 gatttcttcc aaaaccgaac tcaaacgttc ctcaccaaca accatgctca tcttgagcac
     1081 accaccaaag aggtcagatg ttaattcatc cacaaattgc atccgttggt agaatttttc
     1141 aatcatttct ggagtcataa aactttcaag atctgtaaaa atcgtacctt ccttgacaaa
     1201 atcacccttc atccccgtta caacaaactg gtcctgacac gctcgaacct tgaaatgagt
     1261 caaagccttg ttgacaatgg cgtcatccca tgtctgagcc tgaatcaatt cattgttttc
     1321 aaaaatacga gcgccattag caacaaccag aaccactcga tccaccaagg gactcagtag
     1381 ttgtctcatg cggtgaattt cattgcccgt cgcaatgaca aaacgaatgc ccctttgatc
     1441 caactgatct aaaatctttt ccaatcgtgg gagatcaagc tgacctctag catccagcaa
     1501 ggtcccatcc atatctgtcg caattacctt aatcatcatt tactttcctc tggattcaag
     1561 ctaataccac ttcaatccca catgttcatt catttcttta taggctgtat caattcgttc
     1621 cttagtcgct tcatctaact ggtcacgatg actgccatcc tctataaaat cttccaaaat
     1681 ataagtttgg taatgataca agggatatcc ttctggtgaa aaggttccct ttggtgttcg
     1741 attgacccaa gtaggatgag ctttagctgt tccgatagtt gtttttccat ccttcttctt
     1801 gatggtgaca tccatgagaa caccacgttc agtccactta gcattctctt catctcccat
     1861 agattcaatt cgttgattgg aaatgaagtt ccccatttaa tagacaatga gcttcttatc
     1921 tccatctttt tcaatcgttt cagatggttc aacaacgtaa agatgccctc caaagataat
     1981 atccgctccc caatcgatca tcttgtgata aagagctttt tgttcttcag ttggttccaa
     2041 tcgatactca acacccatct gaggcatgat aatggtgata tctgcttcct tctctgcccg
     2101 ttcaatttca gccttcatct tatcttcgtt taaatctgaa agataacgat tatagtcttc
     2161 ctgagaaata tactgctcaa ttccattgaa accataggaa taggctaaca atgcaacctt
     2221 gataccattc acttccttaa tgaccagcgg agcctgatca cgtggttcgt gcgtataaac
     2281 tccgattgga gtgattccag ctttctcaat aatatcggcc gttgaaataa ctccctcaat
     2341 ttgcgaatcc aaaatatgat tatgagctaa atccagcaca tgataacctg cctccttaat
     2401 agcatccata acttcagcag gagcattaaa gagaggataa cccgctaaat aatgatcctt
     2461 attaatggtt tcttcaaaat caccaatagc taaatctgct tgcttgaacc aaggagtcac
     2521 atactcaaaa ttttcatgaa agtcataggt accgtcttct tttttagctg aaaagaaaag
     2581 tccatcgtgg tagagcaaat ccccgtgggc cataattctg gcagtttttt cctcttccta
     2641 ctcctgagac ttttgcttag ttccctcttg agaaatagta tctcgttttt gactagtcaa
     2701 gagattcctt ggaagctttc aaacaataag accaagccca ttgataaacc aactgctagc
     2761 aagagtatcg ccacaaatcc cttattgctc cacttgcgat aactcctaaa aagtttacca
     2821 agcccttcat aaaacgaaaa gctaaaccac cctgatttcg attttgtctt ctttgcatct
     2881 tcattctccc tactttctta tgcaagcctt ttctttttat tatatcacag ataagtattt
     2941 ctttcacaat tgaattgaac ttcccatcta ttttctataa atcctaaatg ccataatgct
     3001 ttcaattctt gtcattttgt gatatcatgt agaggtaatg aaaggaaatg aactaatcca
     3061 cagtggctta ttccaagtat accacttggg ctttggcagt agttaactgc actaaacata
     3121 atataaggag agaaaatgtc tgcaatagaa cgtattacaa aagctgctca cttaattgat
     3181 atgaacgata ttatccgtga agggaatcct actctacgcg cgattgctga ggaagtcact
     3241 ttccccctat ctgaccagga aatcatccta ggcgaaaaga tgatgcaatt ccttaaacat
     3301 tcccaagatc ctgtcatggc tgaaaaaatg ggactccgcg gtggtgttgg actggctgct
     3361 ccccagttag atatctcaaa acgcattatc gctgttttgg tacctaatat tgttgaagaa
     3421 ggcgaaactc cacaggaagc ctacgatttg gaaggcatta tgtacaatcc aaaaatcgtc
     3481 tctcactctg ttcaagatgc tgctcttggc gaaggagaag gttgcctgtc tgttgaccgt
     3541 aacgtgcctg gctatgttgt tcgccatgcc cgcgttactg ttgactactt tgacaaagat
     3601 ggagaaaaac accgtatcaa actcaaaggc tacaactcca ttgttgttca gcatgaaatt
     3661 gaccacatta acggtatcat gttttacgat cgcatcaatg aaaaagaccc atttgcagtt
     3721 aaagatggtt tactgattct tgaataaaga aaatcccgtt gcaagacggg gttttgtgtt
     3781 ataatagagg catgaaaaca aatgatattg tctatggtgt ccacgccgtt accgaagccc
     3841 tccttgcaaa tacaggaaac aaactctacc tccaagaaga tctccgaggt aagaatgttg
     3901 agaaagtcaa ggaactagct acagaaaaga aggtgtccat ttcttggaca tcaaaaaaaa
     3961 atctctctga gatgactgaa ggtgctgttc atcaaggttt tgttctacga gtgtctgaat
     4021 ttgcctatag cgagctagat tacatccttg caaaaacacg ccaagaagaa aattcacttc
     4081 tattgattct agatggtcta accgatcccc ataatctggg ttctatcttg cgaacagccg
     4141 atgcgaccaa tgtttcaggt gtcatcattc ccaagcaccg tgctgtcgga gtaactcctg
     4201 tcgttgccaa aacagccaca ggtgctattg aacacgttcc aattgcccga gtaaccaacc
     4261 tcagtcaaac cttagataaa ctcaaggatg aaggtttctg gacctttgga acggatatga
     4321 acggtactcc ttgccacaag tggaatacaa aagggaaaat cgccctcatc attggaaatg
     4381 aaggaaaagg tatctctagc aacataaaaa aacaggtcga tgaaatgatt accattccga
     4441 tgaatggaca tgttcaaagc cttaatgcca gtgttgctgc ggccattctc atgtacgaag
     4501 ttttccgaaa tagactataa aaaagtttcc agtcatctga ttggaaactt ttttatgatt
     4561 aactatgttc tgtaatgaat ttataggctt cttgaccagc gatagctcca tctccaactg
     4621 ctgttgttac ttggcgaagg tctttcaagc gaacatctcc aactgcaaag ataccgtcga
     4681 ctgcagtctt catgtggcta tctgtcacaa tccagcctgc ctgatcttgg atattcaatt
     4741 ctttaacaaa atcgctaaga gggtccaaac caacatagat aaagacacca ccgaaggctt
     4801 gctctgtcac ttgacctgtt ttcacatttt caaaaacgac agattctact ctgttttcac
     4861 ccttgatttt ccttactaca gaatcccata taaagctgat tttctcattg gcaaaggcgc
     4921 gatcttgtaa aaccttttgg gcacgaagtt ggtcacgacg gtgaacaatg gtaacagtct
     4981 tagcaaaacg agtcaagaag agggcttctt caacagctga atctccacca ccaactacca
     5041 ataaatcttg gtcacggaag aaagcaccat cacacacagc acagtaagaa acaccacgac
     5101 tgttcagttc ttcttctcca ggcactccca aaggacggtg tttagaacca gttgctacga
     5161 taactgtacg tgtttcatat gtttggtcat cagtcatcac tttcttaaaa tcaccatggt
     5221 cttcgacatt ttcaacataa ccataaatgt gctcaacacc aagattttca agtggttcaa
     5281 acatcttttc agccaattca ggtccactaa tattagcgta tcctgggtaa ttttcgatat
     5341 cagatgtatt attcatctga ccacctggca gaccaccttc aatcaaagct acttttagat
     5401 tgcttcgagc agcatacaag gccgcagtca tccctgcagg tccagcaccg ataataatag
     5461 tatcgtacat atagattcct tctttcttgt tgtaactatc tttattctaa ctctttcttg
     5521 tcaatcacgc aaggattatg ccttgaaaac aagaattaaa ctcataaccg caaaggataa
     5581 tactgggaca accaagactc caatcataat catatcatag agatgggctt ggcgagcctt
     5641 ggctgtctta tcaactcccg acatggctct cagaccaatc caaatcccta aaaaaatcag
     5701 aacaaggatg gtggtcaaga tcaaactctc gaaatataaa gaaaatagtt gcagtagcat
     5761 gatttctctc atttctatct tttttaaaga gtaaactcag ctagtccaac taactgagtt
     5821 ttcctttatc tattatatca aatataagtc cgtttgtaac tagcgaagaa ttcttttgtc
     5881 cgctcttctt taggggtgtg gataatctca tccggagttc cagactcgat gattttcccc
     5941 ttatctaaga agagaatctt atccgcaact tgggctacaa aggacatgtc atgactgacc
     6001 aaaatcatgg tctgacctga cttagcagca tctgcaatag acttttctac ttcaccgacc
     6061 aattctgggt caagggctga agttggttcg tctaagagca aaacatctgg tttcatagca
     6121 agcgcacgcg ctagggcaac ccgttgcttc tgtccacctg ataaatggcg aggataatgg
     6181 ttttcacggt ccgaaagccc aaccttagcc aactcttcct tggcaatctt agtcgcttct
     6241 tggtcagata atttcttgac aacaaccaag ccttctttca cattatcaag tgctgttcgg
     6301 cgttcaaaca aattaaactg ttggaaaacc atagacaact tacggcgtag ggcaaggatt
     6361 tcttcttgag tgattttaga aaaatcaact gaaaaaccat caatctgaat agagccactg
     6421 tcaggtgttt caagataatt gagactgcga agaaaggttg attttccagc tcctgaagaa
     6481 ccaatcaagg ctacaacttc ccctttttga atatccaagt ccagatgatc caagacagtc
     6541 tgtcctgaaa aggatttgct taaattcgaa atcttaatca ttaacgaagg tctcctttca
     6601 catctgtttg cactgtatca ggtgcagaaa tagccatttt tctctcgatg aaacgaccga
     6661 gactttcaat tccgatattg actacccaat aaacaagggc aacggagatg aagcgttcaa
     6721 aatagcgata atcagctcca cctagaatct gagcttgggc aaagacttcc acaacacccg
     6781 cactaaaagc tagagatgtt cccttggtca aaccgatgag ggaattaatc aaggttggag
     6841 tagctaccac cgctgcatta ggaataatca ctcgtcgata aacttgcgct cgggtcatac
     6901 ccagactgcg tgccgcctca atctcaccag gattaactga gagaatggct gcacgaatgg
     6961 tttcactagc ataagctgcc tcattaaagg caaaggcgac aatcgcaaaa gctgcagctg
     7021 gaatcgcatt gatattgaga ccagttcccc attgctgatt gagggctttc aaagccaaag
     7081 ggattccgta gtaggtcaac atgagttgca ccaaaatcgg tgtccctttt aagaaactaa
     7141 caaagaaggc ctgcaaggga tataaaatct tgacacgatt gatcttcaca atggcaaaaa
     7201 gaagcgccaa aaccaagcca aaaagggcac caccaattgt caacataatt gttgttggaa
     7261 gttgttggac aattctaggg attccatcaa agaccgaacg taggctaaac agcttgccat
     7321 tcggaatcaa ttgcatcaag ttttggtacc aatctgatgc taaaatcgtt gtaacattca
     7381 taaaaacatc ctcttctgat aatgattcat tctaccatgc ttctgccgtc aatgaaatta
     7441 tttgctacgg tcagatacag actttgtcta cctactagtt tatcatactt tgaaacaggg
     7501 aagttatata ttttatctat caaagagata gataaaaact atttcagtcc cagttcttca
     7561 taagattttc gataaccgat ttgcttaacg gttccatttt ctactaaaat gggccgtttt
     7621 aacaacatac cgtcacttgc tagcaactca gccgcttctt ggtttgacaa acttcctacc
     7681 ttatctttta gccctaattc acggtatttg ataccactgg tgttgaaaaa ttgcttcaat
     7741 tcaaatcctg aggtttctag ccaattcaaa atgacttctt ggctaggtgt ttcttccacg
     7801 atatggacgg ctttatagtc cacacctaat tgatttaatt cttgttttgc ttttttacaa
     7861 gttgaacatt tggggtattc gataaattct aacatgtgct tctccttcta ttgcttctat
     7921 ctttaaaatc tactccttca tgctccaaga gccaagcttt cttttccact cctgcagcat
     7981 aacctgtcag acgcttgcct gctcccaaca cacgatgaca aggtactagg atagaccaag
     8041 gattgcgtcc cactgctcca ccaattgctt gagcagaagc cacttgcagg tcttgagcaa
     8101 tttgtccata ggtcactgtc tgaccataag gaatgccctg taaatagtcc caaactctct
     8161 tttcaaaatt cgttccgatt ggcgccaaga gcaagttgga taaatcctga ggcttgcctt
     8221 taaagtaatc atctaagcaa gcaataactg ggtctaaaat aggatgacta acaacttctt
     8281 ctatcgtttc atctcctagt cccctctcaa aatgcttctg ctcctgaacc caaattccat
     8341 acaaataatg gtcatcagct acaagtgata gaataccaat tggtgaggag tagagtattt
     8401 ttacatactt cttttgcatt atttctttaa tttttgatag gccaagcgtt cgccatctac
     8461 tggcacctta ccaacttgtt taaaaccaag tttttcaaaa atatgttgca taaccttgtt
     8521 ttcagcatgc gtatctgagc gaaaatcaag ataatcaaaa ccttcaatca agccctctaa
     8581 gaaggtttga gcaactcctt ttccctgcac atctgctgcc acagcaatac ggtgaaagac
     8641 tagatactct gactctccag cttgccagtt tccctcataa atagcttcat aggcctcctc
     8701 tggactcttg gtcacagcag cataggctag cagttctccc tcttccaagg ctacgtaggc
     8761 ttgccctgag atgatatcat cgataataac atctgcattt ggatagccat tttgccactg
     8821 gtcactacca gcatctgcta aacatttttt ggcatcctcc atcacctgca tgatggcatc
     8881 tacttcattt ggaaaagcta aacgaatttc catctttttt cctcatttct gactagtttc
     8941 tcccatcata gcataattta agtatttcta caagcagtta aaacttgact ttgtgttttt
     9001 gttattttat aatctagtta tcaaaactat ataaaaagga gttgaaaatg aaaactacct
     9061 tttcctaccc aaaatgggca gaaattccaa acattgacct ctatctggac caggttttgc
     9121 tctatgtcaa tcaggtctgc gcccctatct ctcctaataa agacaagggc ctaacagcat
     9181 ctatggtcaa caattatgtg aaaaatggtt acctgacaaa gcctgacaaa aaaaaatacc
     9241 aacgccaaca gattgcccgt ttgattgcta tcacaaccct caagtctgta ttttctattc
     9301 aagaaatagc ccagacactt aatactctac aaactcaagc aagttcagac caactctacg
     9361 atgcttttgt ggactacatg aaccaaggaa ttgacccagc taaccctatt atccaaacca
     9421 gctgccaaac cgttaaactc tatcatcaaa ctctagactt aatcgatcat actcaagagg
     9481 aggtaatcca atgaacacta gtcttaaact cagcaaacaa ctcagttttg gagaggagat
     9541 tgctaatagc gtgacccatg ctgtgggtgc agtcatcatg cttatcttgc tgcctatttc
     9601 atccatctat agttatgaag cacacggatt tttatcctct atcggcgttt ccattttcgt
     9661 catcagtctc tttctcatgt tcctatcatc caccatttat cactctatgg cctatggttc
     9721 gacccacaaa tatgttttgc gaatcattga ccattctatg atttacgttg ccattgccgg
     9781 ctcatacacg cccgttgtct tgaccttgat gaataactgg tttggctatc tgattattgt
     9841 catccaatgg ggaacgacca tctttggtat tctctataaa atctttgcta aaaaggtcaa
     9901 tgagaaattt agccttgctc tttacctgat tatgggctgg ttggttctgg ctatcattcc
     9961 tgccattatc agtcaaacga cacccgtttt ctggagtctc atggtaactg gcggactctg
    10021 ttatacagtt ggagctggat tttatgccaa gaaaaaacct tatttccaca tgatttggca
    10081 tctctttatc ctaactgcgt ccgtacttca atacatcgct attgtttatt acatgtaaaa
    10141 ctctcagtag gcagagcctg cttagagttt tacaaacgaa tttcccaaag aggaagcaat
    10201 atgaaagcag tcattgcttg tgttcataaa attctcagaa tcatttacaa actactctcc
    10261 accaagtaga cttatcaaaa agaaaaggcg ctaggactga agaaacagtt ctaacgccca
    10321 aattaaaaaa atttcaacta cagtatagca caggaaatga ttttttgcgc ttttttactg
    10381 ttttttcaaa taaaaaaaga caaagtttta tccttgtctt ttagttttag tattgctttg
    10441 gtttcaatgt caataagtgt gtt
//
LOCUS       DAVKEV010000056        10041 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVKEV010000056 DAVKEV010000000
VERSION     DAVKEV010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10041
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.056"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(71..307)
                     /locus_tag="VWZ68_001830"
     CDS             complement(71..307)
                     /locus_tag="VWZ68_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEU9372815.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(375..1295)
                     /locus_tag="VWZ68_001831"
     CDS             complement(375..1295)
                     /locus_tag="VWZ68_001831"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEU9372816.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            1493..1897
                     /locus_tag="VWZ68_001832"
     CDS             1493..1897
                     /locus_tag="VWZ68_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372817.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGRCFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            2113..2694
                     /locus_tag="VWZ68_001833"
     CDS             2113..2694
                     /locus_tag="VWZ68_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9372818.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETSGDLTIVIQKKQ
                     GAPSAKSKMEGVFGNCEILKKDKGYYILRSVKE"
     gene            2691..3968
                     /locus_tag="VWZ68_001834"
     CDS             2691..3968
                     /locus_tag="VWZ68_001834"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEU9372819.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILVPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            3986..4648
                     /gene="deoC"
                     /locus_tag="VWZ68_001835"
     CDS             3986..4648
                     /gene="deoC"
                     /locus_tag="VWZ68_001835"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEU9372820.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            4635..5024
                     /locus_tag="VWZ68_001836"
     CDS             4635..5024
                     /locus_tag="VWZ68_001836"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU9372821.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            5114..6166
                     /locus_tag="VWZ68_001837"
     CDS             5114..6166
                     /locus_tag="VWZ68_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEU9372822.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVKDAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            6310..7845
                     /locus_tag="VWZ68_001838"
     CDS             6310..7845
                     /locus_tag="VWZ68_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9372823.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            7838..8896
                     /locus_tag="VWZ68_001839"
     CDS             7838..8896
                     /locus_tag="VWZ68_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9372824.1"
                     /translation="MFKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            8899..9855
                     /locus_tag="VWZ68_001840"
     CDS             8899..9855
                     /locus_tag="VWZ68_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9372825.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            9940..>10041
                     /locus_tag="VWZ68_001841"
     CDS             9940..>10041
                     /locus_tag="VWZ68_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9372826.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFGINNSN"
BASE COUNT         2867 a         1768 c         2310 g         3096 t
ORIGIN      
        1 gataattgcg attttcattt tctacctttt cctatttgga gacaaaaaaa cagcctctat
       61 ggactgtttc ttatttagca agtttagctg aaagacgagc tttatcgcgg cttgctttgt
      121 ttttgtgaat caaaccttta gtttctgctt tatcgatagc tgagctagca gcacggaaaa
      181 gttcttcaga tgggtttgct tcgaaagctt ttatagcagt acgcatagct gatttttgag
      241 ctgagttctt ttcgttttgt ttaacgttca attcagcgcg tttgatagct gatttaatgt
      301 ttgccaatgt tcttacctcc atatttacta actataccat tatatatgaa aacttacgtt
      361 ttgacaaggg aaaattattt ttttaagtaa atttcatcga tttcatggtt cttgctttta
      421 tgaagaatca cttctgcacg atttctggtt ggttcaatat aattttgtag atttgtgaga
      481 ttgatactgg tccagacctg atgggcaaag gcttccactt ccccaatcgg catctgagta
      541 aaacgataat agtagctatc agggtcgttt tgggctagac tcagcatttt caagaaacgg
      601 tccagatacc aactttcaat atcatccact ccagcatcta catagatgga aaagtcaaag
      661 aagtcagtga tatagagacg atcgttttgt ggattttgaa agacattgat tccctcaaca
      721 attacaaaat cagcagcttt gacactttgt ttctcttcgg gtacgatgtc gtaaacttca
      781 tgagaataga caggaatatc tacatcttgt ccatttttga tgcggtccaa gaagttgaga
      841 agagcttcca tatcatagct ttcaggaaat cctttacgat ttaaaatccc ctgctcaatc
      901 aaggtttgat tgggatagag aaaaccatca gttgtaacca actcaaccgt agcatctgta
      961 aacgtacggg acagtaggat ttgaagtagg cgactggttg tggattttcc aacggcaaca
     1021 ctcccagaaa ccccaataat aaaaggttga gatttacttt cacgttggag gaaaattcct
     1081 tttgaaaagg ctaaatcttc cttagttcgc ttgtaaatct gaatcagatg agccaagggg
     1141 agatagatat ctgtaacgtc ttggagactg atttggtcat taaaactctt gatagattcc
     1201 aattcttctt ctgtcaaagg aggtgttgtc tttcgatgta aagattgcca agtctggcgg
     1261 ctgatttttt caaaatgtaa aaattcgttg gtcatttgtt ttcccctaga tattttgtct
     1321 atcataccat aaaaatctaa aaaaataaag cggtttcttg aatgtggtaa gtcaatggta
     1381 tatagtataa gtgatcaatt tattgatgaa ataggagata gattctactg atttataagt
     1441 ttataagctt ataaaggggg ctttttagtt cacaacttat aggaggtgta ctatgaaaat
     1501 cttaaaacgt tacatattgg aactctgttt tattttaagt tttgctttac cttttataaa
     1561 aggagccaat gcagataatg gtagatgctt tgtggaaacc tattacggtt ttactttttt
     1621 gatggaacat gctattgtaa cagctgtctt tatctattcg tttttaattg ctttcttact
     1681 aaaaaaacga tgggcgaaat ggattgctgc tggtagttat tgctttttag tcctatggat
     1741 tgcgacagag ggttatttct tccgcatgtc actagaagat ttgatacgac tttggacaag
     1801 tttggaaatc ctgacacaaa cgtatcagtt gggcttttat ctaaacattt tgttgggaat
     1861 tttgttgata ataaagtatt ttaaggttaa gcaatagaaa taataatctg cctgattata
     1921 gatgataaac tttttgtttt tatctggact gtgatattta tagttctaaa tggtttatta
     1981 tttataagtg ttgaaagaga ttgaagaaaa tggcttcgtg actcgctttc ttcggtcttt
     2041 ttcgttttat tatcaatttg taaacgattt acaatttgag tcaaattatg gtaaaatagt
     2101 gtcatgagta aaatgtatta tgcagaaaat cctgacgctg ctcacgacat tcatgagttg
     2161 agagtagagt tgttgggaca aaaaatgacc tttttaacgg atgcgggtgt ttttagcaag
     2221 aaaatagttg actttggaag tcaactattg ctcaagtgtc ttgaggtcaa ccaaggagaa
     2281 actgtccttg atgtaggctg tggttacgga cctttgggtt tgtccttagc taaggcttat
     2341 ggagttcagg ctactatggt tgatatcaac actcgtgcct tagatttagc tcggagaaat
     2401 gctgaaaaaa ataatgcaaa agcgacgatt ttccagtcca acatctatga acaagttgaa
     2461 ggacattttg atcatgtcat ttccaatcct cctatccgtg cgggcaagca agtcgttcat
     2521 gaaatcattg agaaaagtaa agatttcttg gaaactagtg gggatttgac aatcgtcatc
     2581 cagaaaaaac aaggggctcc aagtgctaag tccaagatgg agggtgtgtt tggtaattgt
     2641 gaaatcctta aaaaagacaa gggatactat atccttagaa gtgtgaaaga atgagagcag
     2701 ttgatttaat acaaaaaaaa cgagacggtc aagaactgac ttcaagtgaa attgaatggc
     2761 tggtagaagg ctatgtgtca ggaactgttc ctgattatca gatgtctgcc tttgctatgg
     2821 ctgtttattt taaaggaatg acgactcgag aaatctctga tttaacgatg aatatggtta
     2881 agactgggca agagtttgac ctgtcagcca ttgatggtgt gaaagttgac aagcattcta
     2941 ctggtggtgt cggcgataag gtaaccttga ttttagttcc tcttgttgct agcttcggtg
     3001 tgcctgtagc aaaaatgagt ggtcgtggtc ttggccatac aggcggaaca attgataaat
     3061 tggagtccat taagggctat caagtagaac gtagtcaaga ggattttatt cgtcaggttc
     3121 aggatattgg agtatctgtc attgggcaat cagaccagct ggtcaaagca gataagcttc
     3181 tctatgccct tcgtgatgtg accgcaactg tcgacacgat tcctttgatt gcgagttcgg
     3241 tgatgagcaa gaaaattgcg gcaggggcgg atgctatttt gctagacgtg actgtcggtg
     3301 agggtgcctt catgaagacg gttgatgagg cgcgtgagtt ggctcaaact atggtagatc
     3361 ttggtaaggt tgttggacgg aagacagtag cagtgattac ggatatgagc cagcctttgg
     3421 gacgagcgat tggaaatcgt ctggaaatcc ttgaagcatt ggagattttg caaggtcaag
     3481 gacgtcagga tattacccac tttatttgtg aattggctca aattatgctt ggtttggcaa
     3541 atgttaacaa aactgttgaa gaagttcgcc aacatcttga gaatggtcaa gcactggcta
     3601 agtttgagga aatggtgcaa gcccaaggtg gagacttgga agacctctat cgtcctgtaa
     3661 atgtagctca tgtggtggaa atccctgctc aggaaacggg tgtcatttca gctcttccag
     3721 ctatggactt tggtctttat gccatgaggc tgggtgctgg tcgtgcagtt aagtctgatg
     3781 ccttggacta tgaaacagga attgtttttg aaaagaagat tggagactcc gttcaaaagg
     3841 gtgaaattgt tgcaaaagta tacacaaatg aaaaaattcc acctcaacta gttacagatt
     3901 tccaaaaatg tgttaaaata agtgatgaag tgaaaaaaat ccgtgaaatt gtagaaatca
     3961 tctcctaaat ggagggaaaa ccgaaatgaa attaaataaa tatatagatc atacgctttt
     4021 aaaacaagat gcaaagaaaa aacaaattga tagtttgttg tctgaggcta gagagtatga
     4081 ctttgccagt gtttgcgtta atccgacctg ggttgaacat gctaaaaaag gacttgaagg
     4141 cacagatgtt aaggtttgca cagtagtagg tttccctttg ggagcaacaa cttcagccgt
     4201 gaaagcattt gagacaaaag aagctatcca aaatggtgca gatgagattg atatggtgat
     4261 caatgttgga gctctcaaat caggtaattt agccttggtt gagtcagata ttcgcgcagt
     4321 agtggaagca agtggtgata agttagtgaa agtcattatt gaagcttgcc ttctgacaga
     4381 ccaagaaaaa attgttgttt gccaattggc ccaaaaagct ggggctgact ttgttaaaac
     4441 atctactggt ttttcaactg gtggtgctac gatagcagat gttacattaa tgcgtgaaac
     4501 agttggatct gatatgggag tcaaggctgc tggtggagct cgttcttatg cagatgctct
     4561 tgcctttgtc gaagcaggtg cgacccgtat cggaacgtca gctggggtag ctattttaaa
     4621 aggagaattg gcagatggcg actactgagt tgattgaact ggcaattgaa accagcaaac
     4681 atgcatatgt cccctattct cactttccta tcggagcagt tttagtagcc aaagacggaa
     4741 gtgtttacac gggagtgaat atcgaaaatg ctagctatcc tttgaccaat tgcggtgaga
     4801 gaacagctat ttttaaggct atatctgaag gccaaagaga attttcagaa ttgattgtct
     4861 atggtcaaac tgaaaaaccg atctcgccat gtggtgcttg tcgccaagtg atggctgaat
     4921 tttttgaaca agatctaaaa gtgaccttag tcgcaaaaga taaatcgacg gtcgagatga
     4981 cggtcgggga attacttcca tactctttta cagacttaaa ctagtctgag tcgctctctg
     5041 agtggcacgg tccttgtggc caaccaatcc atacttgcaa catcgttgca catcttattt
     5101 aggaggttca gtaatgaaca agaaacaatg gctaggtctt ggcctagttg cagtggcagc
     5161 agttggactt gctgcatgtg gtaaccgctc ttctcgtaac gcagcttcat cttctgatgt
     5221 gaagacaaaa gcagcaatcg tcactgatac tggtggtgtt gatgacaaat cattcaacca
     5281 atcagcttgg gaaggtttgc aggcttgggg taaagaacac aatctttcaa aagataacgg
     5341 tttcacttac ttccaatcaa caagtgaagc tgactacgct aacaacttgc aacaagcggc
     5401 tggaagttac aacctaatct tcggtgttgg ttttgccctt cataatgcag ttaaagatgc
     5461 agcaaaagaa cacactgact tgaactatgt cttgattgat gatgtgatta aagaccaaaa
     5521 gaatgttgcg agcgtaactt tcgctgataa tgagtcaggt taccttgcag gtgtggctgc
     5581 agcaaaaaca actaagacaa aacaagttgg ttttgtaggt ggtatcgaat ctgaagttat
     5641 ctctcgtttt gaagcaggat tcaaggctgg tgttgcgtca gtagacccat ctatcaaagt
     5701 ccaagttgac tacgctggtt catttggtga tgcggctaaa ggtaaaacaa ttgcagccgc
     5761 acaatacgca gccggtgcag atattgttta ccaagtagct ggtggtacag gtgcaggtgt
     5821 ctttgcagag gcaaaatctc tcaacgaaag ccgtcctgaa aatgaaaaag tttgggttat
     5881 cggtgttgat cgtgaccaag aagcagaagg taaatacact tctaaagatg gcaaagaatc
     5941 aaactttgtt cttgtatcta ctttgaaaca agttggtaca actgtaaaag atatttctaa
     6001 caaggcagaa aaaggagaat tccctggcgg tcaagtgatc gtttactcat tgaaggataa
     6061 aggggttgac ttggcagtaa caaacctttc agaagaaggt aaaaaagctg tcgaagatgc
     6121 aaaagctaaa atccttgatg gaagcgtaaa agttcctgaa aaataatgga tggaagtcat
     6181 ttcttaggaa gcggccaagg gccgcttttt taagagttga gacaaagtca ttttgtctca
     6241 gtaaagcttg ctactagaca aactagcaag ttttattgaa ataaaataag actctgaaag
     6301 gaagagcaca tggcacacga aaatgtcatt gagatgcgtg atattaccaa ggtgtttggt
     6361 ggatttgttg ccaacgacaa aatcaacttg cacctacgaa aaggtgaaat tcatgcactt
     6421 ttaggagaaa atggggctgg taagtccacg ctaatgaaca tgttagcagg ccttcttgaa
     6481 ccaactagtg gtgaaatcgc ggtcaacggt caagttgtca atctcgactc cccatctaaa
     6541 gcagctagct tgggaatcgg gatggttcac cagcacttta tgttggttga agccttcaca
     6601 gtggctgaaa acatcatttt aggtagtgaa ttgactaaaa atggtgtgct agatatcgct
     6661 ggagctagca aagaaatcaa ggctctttct gaacgttatg gcttagctgt tgacccttct
     6721 gccaaggtag cagatatctc agttggagcc caacaacgtg tagaaatttt aaaaacactt
     6781 tatcgggggg ctgatatcct tatctttgac gaaccaacgg ctgttttgac tccatcagaa
     6841 attgatgagt tgatggctat tatgaaaaat cttgtcaaag aaggaaaatc aattatcttg
     6901 attacccaca aattggatga aattcgcgca gtttctgacc gtgttacagt tatccgtcgt
     6961 gggaaatcaa ttgaaaccgt tgaaattgca ggggctacca atgctgattt ggcggaaatg
     7021 atggtaggac gttctgtttc ctttaaaaca gagaagcaag cctctaaacc aaaagaagtg
     7081 gttttgtcta tcaaagattt ggtggtcaat gaaaaccgtg gtgttccagc tgttaaaaat
     7141 ctgtccttgg atgttcgtgc tggagagatt gttggtattg cggggattga tggaaatggt
     7201 cagtctgaac tgattcaagc cattacaggt cttcgtaagg ttgaatctgg tagcattgag
     7261 ctaaaagggg attcaattgt aggcttgcac ccacgtcaga ttacagaact aagtgttggg
     7321 cacgttccag aagaccgtca ccgtgatggc ttgattttgg aaatgatgat atctgaaaat
     7381 attgcccttc aaacctacta taaagaacca catagtaaaa atggaatttt gaattattca
     7441 aatattactt cttatgctaa aaagctgatg gaagagtttg atgttcgcgc tgccagtgaa
     7501 ttagttcctg cagctgcact ctcaggagga aatcaacaaa aagcaattat tgctcgtgaa
     7561 attgatcgag atcctgatct ccttatcgtt agccagccaa ctcgtgggtt ggatgtcggt
     7621 gccattgagt atatccacaa acgcttgatt gaagagcgtg ataatggcaa ggctgtcctt
     7681 gttgtcagct ttgaattgga tgagatttta aacgtctcag accgtattgc cgttatccac
     7741 gatggtaaga ttcaaggtat tgtatcacca gaaacaacca ataaacaaga acttggtgtc
     7801 ttgatggctg gtggaaactt gggaaaggag aagagtgatg tttaaaaaat tacaacaaat
     7861 ttcggttccc ttgatttctg tatttctagg aattttactc ggagccattg tcatgtggat
     7921 cttcggttat gatgctattt ggggctacga agaattgttc tatacagcct ttggcagtct
     7981 gcgtgggatt ggagaaatct tccgtgctat gggtcctctg gtcttgattg gtcttggttt
     8041 tgcggttgcc agtcgagctg gtttctttaa cgtcggactt cctggtcagg ctttggcagg
     8101 ttggattctc agtggttggt ttgccctgtc gcatccagat atgccccgtc ccttgatgat
     8161 tctagcaacc atcgtgattg ccttgattgc tggtgggatt gtcggagcga ttccaggtat
     8221 tcttagggcc tatctaggga cgtcagaggt tattgtaacc atcatgatga actacattgt
     8281 cttgtatgta gggaatgcct ttatccatgc tttccctaaa gacttcatgc aaagtacaga
     8341 ttcgaccatt cgtgttgggg ctaatgcaac ctatcagaca ccttggttgg ctgagttgac
     8401 tggtaactca cggatgaata ttggtatttt ctttgccatc attgccgttg cagttatttg
     8461 gttcatgctc aagaaaacaa ctcttggttt tgaaatccgt gcagttggtc ttaatccaca
     8521 tgcttcagaa tatgctggta tttctgccaa gcggactatt atcctatcta tgattatttc
     8581 aggtgccttg gcaggtcttg gtggagctgt tgaaggtttg ggaaccttcc agaacgtcta
     8641 tgttcaaggt tcgtcattag ctatcggatt taacggaatg gcggttagtt tgcttgcggc
     8701 caactcacca attggtatac tctttgcagc cttcctattt ggcgttctcc aagttggggc
     8761 tcctggtatg aatgctgcgc aggtaccatc tgagcttgtc agcattgtaa cagcgtctat
     8821 tatcttcttt gtcagtgttc attaccttat cgaacgcttt gttaaaccga aaaaacaagt
     8881 taaaggaggt aagtaaagat gtctattata accttgctcc ccctcttggt gtcttctatg
     8941 ctgatttact cagcacctct catctttaca agtatcggtg gtgttttctc tgaacgtggt
     9001 ggtgtggtaa acgttggcct tgaaggaatt atggttatgg gtgccttttc tggagttgtc
     9061 tttaaccttg aatttgcaga acaatttgga gcagcaactc catggctatc cttgcttgta
     9121 gcaggattgg ttggtagtgt tttctctatc atccacgcag cagcgacggt tcatttccgt
     9181 gcagaccatg ttgtcagcgg tacggtattg aacttgatgg cgcctgcctt ggctgttttc
     9241 ttagttaaag ttctttataa caaaggacaa accgacaacc taagtcaaac ttttggacgc
     9301 tttgatttcc cagtcttggc aaatatccca gtgattggtg atatcttctt caagtcaact
     9361 agtctacttg gttatctggc gattgccttc tcattccttg cttggtttat tctctttaag
     9421 actcaatttg gtcttcgtct ccgctctgtc ggtgaacatc ctcaagcagc ggataccttg
     9481 ggaatcaacg tctacaagat gagatattta gggattatta tttcaggttt tctaggtgga
     9541 attggcggag cgatttatgc gcaatcaatc tcagttaact tctcagtgac aactattgtt
     9601 ggacctggat ttatcgccct tgctgcgatg atctttggga aatggaatcc aatcggtgct
     9661 atgctttcta gtctcttctt tggactttca caaagtttgg ctgttatcgg ttctcaattg
     9721 ccgttcctac aaggagtgcc agcggtttat cttcaaattg caccttatgt tttgacaatt
     9781 cttgtcttag cagccttctt tggaaaagca gtcgcaccaa aagcagatgg tatcaactac
     9841 atcaaatcaa aataagcata caaaaaaacg tcagttcaat gactgaactg ccccccaaaa
     9901 gttagacaga aaaaatctaa cttttggggt gtttttatta tgaaactaac ttatgatgat
     9961 aaagttcaga tctatgaact tagaaaacaa ggatatagct tagagaagct ttcaaataaa
    10021 tttgggataa acaattctaa t
//
LOCUS       DAVKEV010000057         9790 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVKEV010000057 DAVKEV010000000
VERSION     DAVKEV010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9790
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.057"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            273..368
                     /locus_tag="VWZ68_001842"
                     /pseudo
     CDS             273..368
                     /locus_tag="VWZ68_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(621..1241)
                     /locus_tag="VWZ68_001843"
     CDS             complement(621..1241)
                     /locus_tag="VWZ68_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU9372827.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1241..1723)
                     /locus_tag="VWZ68_001844"
     CDS             complement(1241..1723)
                     /locus_tag="VWZ68_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEU9372828.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1723..2565)
                     /locus_tag="VWZ68_001845"
     CDS             complement(1723..2565)
                     /locus_tag="VWZ68_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEU9372829.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2660..3460)
                     /locus_tag="VWZ68_001846"
     CDS             complement(2660..3460)
                     /locus_tag="VWZ68_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEU9372830.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3604..4983
                     /gene="glmU"
                     /locus_tag="VWZ68_001847"
     CDS             3604..4983
                     /gene="glmU"
                     /locus_tag="VWZ68_001847"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEU9372831.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4993..5538
                     /locus_tag="VWZ68_001848"
     CDS             4993..5538
                     /locus_tag="VWZ68_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9372832.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5550..5864
                     /locus_tag="VWZ68_001849"
     CDS             5550..5864
                     /locus_tag="VWZ68_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEU9372833.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAAIFLLILLVLAMK
                     LL"
     gene            5881..6573
                     /locus_tag="VWZ68_001850"
     CDS             5881..6573
                     /locus_tag="VWZ68_001850"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEU9372834.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6650..7141
                     /gene="rocS"
                     /locus_tag="VWZ68_001851"
     CDS             6650..7141
                     /gene="rocS"
                     /locus_tag="VWZ68_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEU9372835.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7239..7829
                     /locus_tag="VWZ68_001852"
     CDS             7239..7829
                     /locus_tag="VWZ68_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEU9372836.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAD
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            7838..9601
                     /locus_tag="VWZ68_001853"
     CDS             7838..9601
                     /locus_tag="VWZ68_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEU9372837.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         3025 a         1702 c         2086 g         2977 t
ORIGIN      
        1 aacaccccaa aagttagatt ttttctgtct aacttttggg gtgtagttca tgtacacctg
       61 atatgatgcg ttttataatt ttaaagactt tttgaccagc ctcatttttt taacttgata
      121 ctcagtgaaa agcaaagatt aaactaggaa gctagctgta ggctgctcaa agaacagctt
      181 tgaggttgca gataaaactt gtgaggtcac caacatatat aatgtgaagc tgacgtggct
      241 tgaatagatt ttagaagggt atgagtctgg aagttttaat ggataatgca agattccata
      301 gaatgggtaa gctagagttc ttatgtgaag agtttgggca taaactttta ccttttcctc
      361 cctactcatc ttagtataga aaagtgaatc taaaatagta cataactgct tctaaaacat
      421 tcttataaat tgatttaaat tctcaaatca tattattcag ttcttatttc attttgctct
      481 acaatcctgt tgagaagaca cgtgttcata tcaaaaaggt attggcaagt tgcaatacct
      541 ttttacaagg ttcttttgtc ttatttttgt ttcaactgac tatatctcct atggttctag
      601 ttcagaaggc taggctataa ttatgattga taagaagtat cattccaagt attgagagtg
      661 aatgtttcaa aatcatgggt ttctataatg gtcaggctgg catttgctag accgccatct
      721 ttacgaagaa gtggttcttt atagcctagg agagtacgaa gactggcagt aagattggcg
      781 ccgtgtccga caattagaat acgctcagct ggactatctt ttaatgattt gataaattgg
      841 atggtccgtt gagttgtact atagagggat tcggctccga acattcgagt gtcaaattga
      901 gcaagatttg aacgaaaagc ctggatttgt tgcgggtaaa tagcttccaa ggttgcaatt
      961 ttcaaacctt ctaacttccc aagttgccat tcacggagat taggaacgat ttctaaagaa
     1021 cagggggtat agagttgact ttggataatc tcagcagatt tgaccgctcg aggtaaatca
     1081 cttgaataaa tctgatcaaa aggaatttcc ttgagatact ggccaagtcg ttttagggtt
     1141 tcaatggatt caggaagaag aggagaatca ccgctagcac cttgaaaacg accttcttgg
     1201 ttccagaggg tacgaccgtg gcggacaaag tagagtttca ttacttgatg tcctccaaaa
     1261 tatctacaaa gtctgccttt acaaagctag ccaagtcttg tggcgcgacg ataatgctgt
     1321 gtccgacttc gcctgcagag acaatcattc gatccaaatc tagagcaatt ttatcgataa
     1381 aaatgggata attgtgtttc tgacgaattc cgacaggatt attggctcca tgaatgtaac
     1441 cagttgtttt ttctaagtcc ttttgtggaa tcatgctcac ttttttattg ccagaaattt
     1501 tagctagttt cttttcagac aagtgctgag tgatagggac aattccgata atcggtccgg
     1561 tcttgtctcc caaaagcgcc aaggttttga aaatctgatc tcgttcataa ccttgaggaa
     1621 gctctccttc tagggcattg atttgaatcc cctgatgagg gatagctgct ttagatagga
     1681 tttgttccac caatgttttt ttgattttaa ctttttttgc cattatttat atttatcctc
     1741 caattgactc atccaaatac caagccagat tcccagcgca aagaagaagg cgatgatgac
     1801 ataaccgaca agtgaaagtc ctgtgtattg gatactttca gcgtttcctg catttggaat
     1861 taagatcaaa agggtacttg ataggacgat accgatgatg aaatgataga cgcgtgagtg
     1921 gtagttgttt aaggcataat ccatcaattt tgaaaaaacg atgagagttg cacctgcacc
     1981 aattccaatc ggaaagaagg ttcccaagag atcaaaagtt ttaaaaccag tcaacatagg
     2041 agcatagagt cccaaaatca aaagtaagtt cgatgggctg aggccaggaa ccaagacgcc
     2101 aagggccaat agtgcgcctg ctaggacgaa gttaagaaag ctggcgctta aggttccaac
     2161 gacaaaattt aaggcataga gtcctaatcc agaaatgata aaggttgtcc ataaccaagc
     2221 taaatcaatc ttgtctcggt cagattctcg agttgattct ttgaggaggc taggaactgt
     2281 accgataata gctcccgcaa agctccataa tacaaagacc tgataatttt caagcaggta
     2341 ttcaatcggg taggaaaata agccgattcc cagaagcata ccgatggcaa ctggaataaa
     2401 gtacaaaaca ttttctttaa ggtctttaaa gggatgggcc agaaagccaa tcattcgttc
     2461 atagattcct aagattgctg ctagaacccc tccggaaatt cccggtagga taaatccaag
     2521 agcaattaca atccctttaa taacgcgtgc taaccatgag agcatatatt tcctccaact
     2581 atttctattt caaaaaatcc ttactatatt gtatcacaat cagacacaaa aagaaaaagc
     2641 aaatgataaa caaatgcttt taaggtttta aaaaaagttt tcgaaaggtt tcttctttat
     2701 tttttaaggg agagataacg ttgatatcta aatcgtggtc aaagccggca atttttcctt
     2761 tagatgtgta ttggtgaata tcataatcta aatcagtttt aggactgctc tccaaaaatc
     2821 ctgagtctga gccgtaggac ggaatccaaa cagaggtaaa cttgcctgta tcaatactgt
     2881 gttcttccat gaagtagaca ccaacgtaga tgccgatgtt tttagcacct agtgatgcta
     2941 gttttgctcg aaagttttcg acaccttcgt tcatattaga catggttttg tcttccacgt
     3001 caagccaata gtaactaggg ctgtaaggag aggcagcatt gtagaaaact tcggcagcct
     3061 tttccatttc ttggacactt tttccagcta cataagcgta gacagcaact gggacattcc
     3121 gcttttgaag ttcagtgata tgactcttat aggccttgtc tattccattg ataaatgaag
     3181 catcattttc ttttgttgtt tgagcaccac tgtgaacacg aacaatagca cctgaaatat
     3241 tttgtgagag ggcatcgtag ttgatttcct caggacgctg ccagccagag aggtcaataa
     3301 tcggtttgtc taagtgtttc aaagcctgtg cttcaatctg tgctatattg gattttgttt
     3361 taaacgattg gctgtcatta agtgggcgat tgatgattaa aatgaacatc ataatcccaa
     3421 aaaaactaaa taaaataagt ggatgaattt gttttctcat atcttataag tctaccctaa
     3481 aaatcaaaaa aaatcaaaaa aatgggttaa ggaagagact ttagagcatt ttttcattca
     3541 agagtgcgga atgatttgaa atatggtata ataaaaggga atttctacag aaaagagaag
     3601 attatgtcaa attttgccat tattttagca gcgggtaaag ggactcgcat gaaatctgat
     3661 ttgccaaaag ttttgcacaa ggttgcgggt atttctatgt tggaacatgt tttccgtagt
     3721 gtgggagcta tccaacctga aaagacagta acagttgtag gacacaaggc agaattggtt
     3781 gaggaggtct tggctggaca gacagaattt gtgactcaat ctgaacagtt gggaactggt
     3841 catgcagtta tgatgacaga acctatctta gaaggtttgt caggacacac cttggtcatt
     3901 gcaggagata ctcctttaat cactggtgaa agcttgaaaa acttgattga tttccatatc
     3961 aatcataaaa atgtggccac tatcttgact gctgaaacgg ataatccttt tggctatgga
     4021 cgaattgttc gtaatgacaa tgctgaggtt cttcgtattg ttgagcagaa ggatgctaca
     4081 gattttgaaa agcaaatcaa ggaaatcaac actggaacat acgtctttga caacgagcgt
     4141 ttgtttgagg ctttgaaaaa tatcaatacc aataacgctc aaggcgaata ctatattaca
     4201 gacgtcattg gtattttccg tgaaactggt gaaaaagttg gcgcttatac tttgaaagat
     4261 tttgatgaaa gtcttggggt aaatgaccgt gtggcgcttg cgacagctga gtcagttatg
     4321 cgtcgtcgca tcaatcataa acacatggtc aacggtgtta gctttgtcaa tccagaagca
     4381 acttatatcg atattgatgt tgagattgct ccggaagttc aaatcgaagc caatgttacc
     4441 ttgaaagggc aaacgaaaat tggtgctgag actgttttga caaacggtac ttatgtagtg
     4501 gacagcacta tcggagcagg agcggtcatt accaattcta tgattgagga aagtagtgtt
     4561 gcagacggtg tgacagtcgg tccttatgct cacattcgtc caaattcaag tctgggtgcc
     4621 caagttcata ttggtaactt tgttgaggtg aaaggatctt caatcggtga gaataccaag
     4681 gctggtcatt tgacttatat cggaaactgt gaagtgggaa gcaacgttaa tttcggtgct
     4741 ggaactatta cagtcaacta tgacggcaaa aacaaataca agacagtcat tggagacaat
     4801 gtctttgttg gttcaaattc aaccattatt gcaccagtag aacttggtga caattccctc
     4861 gttggtgctg gttcaactat tactaaagac gtgccagcag atgctattgc tattggtcgc
     4921 ggtcgtcaga tcaataaaga cgaatatgca acacgtcttc ctcatcatcc taagaaccag
     4981 taggagccta tcatggagtt tgaagaaaaa acgcttagcc gaaaagaaat ctatcaagga
     5041 ccaatattta aactggtcca agatcaggtt gaattaccag aaggcaaggg aactgcccga
     5101 cgggatttga ttttccacaa tggggctgtc tgtgttttag cagtaacgga tgaacaaaaa
     5161 cttatcttgg tcaagcagta ccgcaaagct atcgaggctg tctcttacga aattccagcc
     5221 ggaaaattgg aagtaggaga aaacacagcc cctgtggcag ctgcccttcg tgaattagag
     5281 gaagaaacag cctatacagg gaaattagaa ctcttgtacg atttttattc agctattggc
     5341 ttttgtaatg agaagttaaa actatattta gcaagcgatt tgacaaaagt ggaaaatccg
     5401 cgtccgcagg atgaggatga aaccttggaa gtccttgaag tgagcttaga agaagcgaaa
     5461 gaattaatcc aatcaggtca tatctgtgat gccaagacaa ttatggctgt tcagtattgg
     5521 gagttgcaga aaaaatagag gaggtcagta tgggtaaatc tttattaacg gatgaaatga
     5581 ttgaaagagc taatagaggc gaaaaaattt caggtcctcc tttgctagat gataatgagg
     5641 aaactaagat tttaccaacc tcttcttccc gttttggtta tgccaatcct aaggatcatg
     5701 gttttagcca ggaaaccttg aagattcagg tcgaaccatc tattcataaa agccgtcgta
     5761 ttgaaaatac caagagaaat gtcttcaatt ctaagttgaa taaaatctta tttgcggcca
     5821 tctttctctt gattttgctt gttttagcaa tgaaactttt gtaatagaaa aggaattgaa
     5881 atgaaaatag gaattattgc tgctatgcca gaagaactgg cttatctggt ccagcattta
     5941 gataataccc aggagcaagt tgttttgggg aatacctatc atacaggaac cattgcttct
     6001 catgaagtcg ttcttgtaga aagtggaatt ggtaaggtca tgtctgctat gagtgtggcg
     6061 attttggctg atcatttcca ggtggatgcc cttattaata cgggttcagc tggggcagta
     6121 gcagaaggta tcgctgttgg ggatgtcgtg attgctgaca aattagccta tcatgacgtg
     6181 gatgtcacag cttttggcta tgcttatgga caaatggcgc aacaaccgct ttatttcgaa
     6241 tcagacaaaa cctttgttgc tcaaatccaa gagagtttat ctcaattgga ccaaaactgg
     6301 catcttggtt tgattgctac aggagatagt tttgttgcag gaaatgacaa gatagaagcg
     6361 attaagtccc atttcccaga agttttagcc gtggagatgg agggggcagc tattgctcaa
     6421 gcagcgcatg ccctcaatct cccagtctta gtcatcagag ctatgagtga caatgccaac
     6481 catgaagcaa acatcttttt tgatgagttt attatcgaag ctggacgtcg ctctgcccaa
     6541 gtcttgttga cctttttgaa ggctttagat taagcggaaa tttgacagtt tttctagctt
     6601 atgataagat ttaagtaaag aaaagctaga aaacgtttca gaggatatta tgagtattga
     6661 aatgaccgtc agtgagattg cagaggtctt aggattatct cgccaagcaa tcaataaccg
     6721 tgtcaaagaa ttaccagaag aagacacaga taaaaatgac aaaggggtaa cagttgttac
     6781 cagaagtggc ttgattaagc tagaagaaat ctataaaaaa acgatttttg aagatgagcc
     6841 tgtcagtgaa gatgtcaaac aacgtgaact gatggagatt ctagtggatg agaagaatgc
     6901 agaaattctt cgtctttatg aacaattaaa agccaaggat cgtcagttat cagaaaaaga
     6961 cgagcagatg cgtatcaaag accgtcagat tgctgagaaa gacaaacaat tagatcagca
     7021 acaacaattg acccttcaag ccatgaagga tcaagaaaat cttaagctag agctggacca
     7081 agcaaaagaa gaagtccaat ccactaagaa aggctttttt gctcgtttat ttggaggata
     7141 atcaaggagc tgtttaggtt aaatgctaac ctgatggctt cttttgtttg tgaatagtat
     7201 agttgattag aacagagaca gtagaggaga ggtacagaat ggaacgatta gaagattaca
     7261 ttgcttttga cttagaattt aatcagcacg aaggacaaac acacttgatt caagtatcgg
     7321 cagtgcgttt tagagatggt cgggaaatcg atgcctatga ttcctatgtt cataccagcg
     7381 tccctctaaa aagctttatc aatggtttga ccgggattac agctgagacc ttaaaagatg
     7441 ctcctccagt tgagaaagtc ttagaagaat tccaagagtt tgtgggttct ttgctgatga
     7501 taggctacaa tgctgctaaa agtgatttac ctattttagc agatcatggt ttagactata
     7561 gccaacagta caaggtggat ttgtatgatg aagcttttga acgtcggagt tcagatttac
     7621 atggtattgc caatctcaaa ttgcaaactg ttgcctcatt tcttggattt caaggtcagt
     7681 ctcataatag tttagaggat gctcggatga cggcgcgtgt ttacgaatcc ttcttagagt
     7741 cggatcaagc tagggaattg ttagagacag aaagtagctt atcaaacaat ccttttggtg
     7801 tcttggactt gtctcaatta tttgactagg agtgcctatg aaacctgaaa aacctaaaaa
     7861 attgggtctt aaacagattt acctcaatct tgataaaatc ctctttctat ttttcttgat
     7921 ttttatgata gtggagtatt tgtgggtacc attcaattca tggttggcta gcttcttatt
     7981 agatcagaca ggttatcttt ttatttccta taacaatgtc ttagccatcc ttactcattc
     8041 tccattgatt agtctagctt ttttagcctt gattgtaatt aaccttctgg ttgcttattt
     8101 tcaaatagga ctcctcttta ttggtgctcg tcatctcctc tataatgaaa agcgaaggct
     8161 aattgagtat atccgcaagg ttttccatga aagttttgga tttatgaaaa agctaacttg
     8221 cgctaaagcc ttgtttatct ttttctatat agctatgctt tttcctttta tacggaaaat
     8281 gctgaagatt tattatctta ataaaatcgt cattccagag tttatccaag cttatttaga
     8341 agataaatat tggatgtggt ggctgagcat cctacttcta tctcttatct ttctctatgt
     8401 ctctgtcaga ttgatgtttg cccttccgaa gattgtatat gatcagctga ctgttcgaga
     8461 agcagtgatg tttagcttgg agaaaaccaa gaagagagtt actttttatg cttggaattt
     8521 attttacatc ttgctcaaag cacatttatt attttatctt cctttgattc ctttattatt
     8581 ggctcaaact ttggtagatg atatcactca gagagagtct ctgattcttg gtattttgaa
     8641 ttttgtcgtg attaaaaatc tctattatat ggctctgact tattttttgg ttaaatttgt
     8701 ttcatttttg acaggaaagg agctggatat gcttcctagg agagaaaaag atcacatcgt
     8761 gcgatggggt gtcatgactt gtgccagtct tttctttgcc ttagaaggtt atatttatct
     8821 ggaggctccc atggttcatc tacctcaact tatttctcac cgaggggttt ccaatgcaaa
     8881 tgggattcaa aatacagtag agtccttgga aactacagca caactcaaac cagacttggt
     8941 ggagacggac gtgcaggaaa caaaagatgg gcagtttgtc atgatgcatg atgctaactt
     9001 gaaaaatcta gcaggtatca ataaaagtcc tcaagactta aacttggagg agcttaaagg
     9061 gattgatatt tttgaaaatg gctaccagac taaaatttca agctttgaag attatctcag
     9121 tcgagccaac gaacttggtc aaaaattact aattgaaatt aaaaccagta aaaaagatag
     9181 tccagacatg atgaaccgct ttttagcccg ttatgctgca aagctcaaga tttatggaca
     9241 tcaaatccag tctttagact accatgttgt cgaaaaagta agacagtatg atgccgaact
     9301 gccagtttat ttcatcatgc cctacaattc tgtctttcct aaaacaagag cgacaggata
     9361 tactatggag tactcaacct tggatgaata ttttgtaagc aaactatgga caacggatca
     9421 gaaactttat gtctggactg tcaatgattc agaagctatc agcaaatctc ttcacttagg
     9481 agtagatgga gtgattacag atgatttgga aaaagttcag cgggaaatag aagtagccca
     9541 agaagatcca gaatatacgg atttgctctt gaaaaaagca ttggaattct ttgaatttta
     9601 gtaataaaaa agaggaacgg ttgttcctcc catgataggt aagtattctt gtgaatgctt
     9661 gcttttttgt ggttgcaatc cgtttacgag aattgtttgt attgttcttg tttcaattta
     9721 ctttatagtg ctttgaagtt ggaatgctac actataactt ctaaaatata gtaaaatgaa
     9781 ccaaaaatag
//
LOCUS       DAVKEV010000058         9714 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVKEV010000058 DAVKEV010000000
VERSION     DAVKEV010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9714
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.058"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            364..951
                     /locus_tag="VWZ68_001854"
     CDS             364..951
                     /locus_tag="VWZ68_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372838.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            complement(1038..1241)
                     /locus_tag="VWZ68_001855"
     CDS             complement(1038..1241)
                     /locus_tag="VWZ68_001855"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372839.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(1538..2242)
                     /locus_tag="VWZ68_001856"
     CDS             complement(1538..2242)
                     /locus_tag="VWZ68_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU9372840.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAYLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(2312..4138)
                     /gene="glpO"
                     /locus_tag="VWZ68_001857"
     CDS             complement(2312..4138)
                     /gene="glpO"
                     /locus_tag="VWZ68_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEU9372841.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKSDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPAANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            complement(4180..5688)
                     /gene="glpK"
                     /locus_tag="VWZ68_001858"
     CDS             complement(4180..5688)
                     /gene="glpK"
                     /locus_tag="VWZ68_001858"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEU9372842.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(5847..7274)
                     /locus_tag="VWZ68_001859"
     CDS             complement(5847..7274)
                     /locus_tag="VWZ68_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9372843.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIHYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            7439..8311
                     /gene="hslO"
                     /locus_tag="VWZ68_001860"
     CDS             7439..8311
                     /gene="hslO"
                     /locus_tag="VWZ68_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEU9372844.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            8298..9278
                     /gene="dusB"
                     /locus_tag="VWZ68_001861"
     CDS             8298..9278
                     /gene="dusB"
                     /locus_tag="VWZ68_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEU9372845.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIETLLQLEKA"
     gene            complement(9508..>9714)
                     /locus_tag="VWZ68_001862"
     CDS             complement(9508..>9714)
                     /locus_tag="VWZ68_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HEU9372846.1"
                     /translation="YLNANGDMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVN
                     GSGALAVNTTVDGYGVNANGEWVN"
BASE COUNT         2772 a         2214 c         1930 g         2798 t
ORIGIN      
        1 aaatacgtct atttattttt tattgttttt tattgtagag cagacccaag cgaatgaaca
       61 taggttgtaa aaagcaaatg aaaaaactgc gaggataata gcttctgtgt ctaaataacc
      121 catttcgaga cctcttttca acaacaacaa gcctgtagtt tcgataacga tcaaacataa
      181 aaatatataa aaaattttcg cattaagcat attgttaccg ctttcttttt atttggtttt
      241 attgtataat aaaagttgaa aaaaatcaaa aatacaaagg agtttccgtt atgtctaaga
      301 tgtttaaatg catgtgtttg ctagttatgt ctgttttctg tatgtctagc atttccccgt
      361 cgcttgtttg tttttgctga tgatagctta tcggcaaact ctaaagttgt atctggtgag
      421 gctcagtttg agaatggctc atcagtgcgg ttcggagata cgcaagtaaa tattttaagc
      481 gatgaagttc ttgaggttgt caatccagat ggaagtgtag acactattga acgacgtgct
      541 gacggcgtct atatcaatgg ggcattttat atggcttatc aaaagaatga aatcgaccta
      601 aatatatctt ttagatcata cgatcctaat gtttggaatt acgtcaacac aatacatggg
      661 aataaacaag ctaacacatt cgctaacttc atgactggtg ctggaatcag ttatatgatt
      721 ggtaggatag gtgctttatt ggggggtcca tggggtgcaa taattggtgg agcatatttt
      781 ggtatacaag cttatcagtc ttacttggat tcacaaagcc catatccata ctacataaca
      841 agtacttata tccatgttgc tcaaagaaaa tggaagttta tcactgaata ctatagaaac
      901 tcaaactata ctgggtatgt aaaaaccgta acaacctacg tgaatttcta aaatataaac
      961 cctgcctaga tataaaggca gggtttatat tttagttaat tgctcaagta atttgtaagc
     1021 ataatacttg cgaaactcta tttgttcaag cggttcaaaa gctcttgttt tttaccctca
     1081 agctcagctc tcctttgctc gatttcttca cgtttttggg cgatttctgc ttgcgcctcg
     1141 ggagtttcca aagtgccttg tgacttgtga aattctacta gcatatcaac gatttttggg
     1201 tctaattcgt tgacataatc aggatttgac catttcggca cgttgcttgc aggtgcttgc
     1261 tttttgccgc cttttttggg cgttttggct tgttgttcag ctttctgact gtagttgacc
     1321 tcgtggaatt ttcgtgcttg atatgatgcg ttttattatg agaagattta cttcattttt
     1381 tgctgaaatt gggctcttgc ccaagctcta tcaacataat tgttttctaa tactcaatga
     1441 aaatcaaaga gcaaactagg aagctagccg caagctgtac ttgagtacgg taaggcgacg
     1501 ctgacgtggt ttgaatttga ttttcgaaga gtataaacta gaaaagtgag aatacaagca
     1561 ctgccaaggc tgctccgata acagggccta caacaggaat ccaagcgtaa gaccagtctc
     1621 cgtctccctt gtttggaatt ggcaagatgc tgtgcatgat acgaggtcca aggtcacgag
     1681 ctgggttcaa ggcataacct gttgtcccac ctagtgatag accgataccg acaatcaaag
     1741 ttcccactgc aaaggttccg atacctgcct gaaagtcgta aagacccaaa gcaaagattg
     1801 tcaacaccaa aacaaaagtt ccaaggattt cgctaatcaa gtttgataca gtatccttga
     1861 tggctggtcc agtactgaag gttgccagga tattgcctgc attttcttct gcctcatagt
     1921 gaggtttgaa ttgcaaccaa accaaaatct gacccagcat ggcccctgcg aactgggcta
     1981 agatataagg caaaacggaa gcccaaggca aaccaccttt taaggccaca ccgatggtca
     2041 cagctgggtt taaataagct ggactgagct tgccagatac aaagactgca accgcaactg
     2101 caatccccca acccatagta atcacaatcc aacctgagct attgctcttg gttttaggaa
     2161 gaaccacacc tgcaacaaca ccatttccta gaagaatcag gattaaagtc cctagaaatt
     2221 ctccaaataa ttcattcatc atctttctgt ctccattaaa aagaagggac gggcgacaag
     2281 gaatgctgcc ctccacctct tttatttttt cttaattttt taattctgct aaatcgttgt
     2341 tagcgagagc tgcttcgaca tcagcacggt aagttgcttt ttcttcttct gtccagtcat
     2401 agaatcgtcc catttcatcc aaaattggct caacgatact atccaagcta tcacgcataa
     2461 agagcatgtg attggtacga cgaagaagga agtcaactgg gctaagagtc aactcattgc
     2521 gcattgcata gtgaagggac aaagtatctg ccaagctgag tcctggcgct tgttccaagc
     2581 tgtgagcaag tgcaaagact ttcggtgcat ttgaaccgta aagatttgcc agatagtgag
     2641 cttccttgct atccaaacca cgtgatactc caagttgcgc aaaggcttcg atttctgaat
     2701 ccacatttgc tgggttcaat tctccacctg aaacagggta agttttagaa ttgatcaatt
     2761 taaagctacg gtcaaattct gctttgagga tgtcaaccac gcgctccata gctccttcag
     2821 ccatcttacg gtagtctgtg attttaccac cagcaagagt caagagacca ttgtcatcac
     2881 ggtccaagct agacccacga gaaactgcag atggatccaa atgtttctca gatgtgctac
     2941 tttcaagctt gctgacagca gactcaacat cttcacgtgt tttttctttg gagagataag
     3001 attcaacagt cgcaatcaag ttgtcaaagc tttcatcact gatggtaccg ttatttccac
     3061 cattatagtc agaggcactg ttccctgcaa tcaatggacg aagacctgcc cagctgcttt
     3121 cgatatcatc aatggtgatg ttggattctg ggaagcggtt gttgacaatg ccaagtagat
     3181 aatctacatc ttcttgagtt acttttggat gctccaaatc acctgtgtag tctgtatcag
     3241 ttgtaccaaa gtaagtcttg ttttcacgtg ggagaacaaa gaccatacga ccgtcaccca
     3301 aacctgtgtc gaagtaaact ggctgtgaaa ccttgatttt gcttgaatct actaccaagt
     3361 gaactccctt agttgggcgc atttgtgaga attgcgttcc cttattagac aaattacgta
     3421 ctttatcact ccaaggacct gttgtattaa taaccagacg ggccttgatt tcaaacactt
     3481 ggtctgtcaa gagatcacga gctacaacac ctgtaatctt gccactttcg tcaaagagga
     3541 agccttctgc cttcacgtgg ttggcaatga gggcaccgtc ttggttggca cgtttgatgt
     3601 tttcaatcac gagacgcgca tcgttgttac ggaagtcaag atacactcca cctcctacca
     3661 agccttcctt cttcaagttt ggctggcgtt ccaagacttg atccttgctc aaaaccttgt
     3721 tcgcagctgg tgtgttgcta acacctgcca agaggtcgta caagtccatg gctactttaa
     3781 gacggaagag gctaaaggtt gctccatctt catcgtaaac tggtaagagc attggatctg
     3841 attttggaat gtgtggagcg atttgttgaa ccactgcacg ttcagaaacc gtatctgaga
     3901 ccacttctac gtcaaattgt ttgaggtaac gaagtcctcc gtgaaccaat tttgttgaac
     3961 gactagatgt tccttctgca aagtcttgca tttcaatcaa accagtctca agaccgctag
     4021 ctgccgcctg caaggctaca ccagctcctg tgattcctcc accgataatc aagaggtcca
     4081 gggtacgttc ctgcattttt ttaattgaca attcacgtgt tttctttgaa aattccatat
     4141 ttacacactt tctaaataaa tcgctttatt ctgccagtat tagtcgtcta cttccgcaaa
     4201 gacttgagtt gctttcacag ccttcttcca gcccttgtag agttgttcct tgcgagattc
     4261 gttcatagat ggctcaaaga gttctcctgt ctcgttcaag agtttcaact cgtccaagtc
     4321 tttccagtac cctactgaca aacctgctag gaaggccgct cctagagctg ttgtttccag
     4381 gtttttagca cgtgcaatgt caatgcctaa aatatccgcc tggaactgca tgaggaagtt
     4441 gttcatggct gcaccaccat ccaccttcag tacttgaatg gcggtctgag tatccacttg
     4501 catggtgtcg atgatatcac gcacttgata agcaatagat tgcaaagtcg ccttgataaa
     4561 gtcttctttg cttgttccac gagtcaaacc aaagacggaa ccacgagcat tttggttcca
     4621 gtatggagcg cctagacctg taaaggctgg aacgacataa acttcatcgt tgttgtgaga
     4681 atcacgagcg tatttttcag attctggtga attttcaacc atgcgaagac cgtcacgaag
     4741 ccactgaata gcacttcctg cgatgaagat agaaccttcc aaggcataat aaaccttacc
     4801 gttgattccg taaccaatgg ttgtcaagag gttgttttca gacaactgca tctcttcccc
     4861 agtattcatg atgatgaaag agcctgttcc ataagtattc ttaaccatac ctggctcaaa
     4921 agccaactgt ccaaagaggg ctgcttgttg gtccccagcc atacctgaga ttggcacctc
     4981 tccaccgtag aaatggaatg gagctgtctt gccgtagatt tcggagttag aacgaacttc
     5041 tggaagtata gccttcggaa tgttaaggat ttccaaaatc tcatcatccc atttgagttc
     5101 tttaatgtta taaagcatgg tacgagctgc atttgagtag tcagtcacgt gagccgcacc
     5161 gtcagtcaat ttccaaacca accaagtatc gatagtacca aagagcaatt cccctttttc
     5221 tgctcgctct tgagcacctt ctacatgatc caaaatccaa cgaaccttgg tagcagagaa
     5281 gtaagcatca ataatcaaac cagtcttttc atggaatttt tccacataac cttggctttt
     5341 tagttgctca gccaaaggtg ctgtctggcg tgactgccaa acgatagcat tgtagatagg
     5401 aagtcctgtt ttcttatccc agacaaccgt tgtttcacgt tggttggtaa tcccgattgc
     5461 ctcgatttga tttggcttga caccactttc gatgaaagca cccgcaataa ctgactgaac
     5521 agagttccaa atttcattgg cattgtgctc aacccaacct gcctgaggga aaatctgggt
     5581 aaactctttt tgactcgagc taaccttttc cccttttttg ttgaaaatga tggcacgaga
     5641 acttgtagtt ccctggtcaa tggccatgat gtatttttct tgtgacatgt actgtcctcc
     5701 tgataaagat cttgaggtgt ttcctcttta cacttactag tatacaaaat aaagcgcttt
     5761 cttgtttatc aacttttttt aatttttaaa aaaatgtgag gagattgtgt gaatttcaca
     5821 aaaaagacct ggattaacca agccttttaa gtgaataata actggcgaat cgctaccaaa
     5881 tcctccatat ccaagtcatt ttttaaataa tagactggtg tctgttcctt cttatgaatc
     5941 gggttattgg taaccagcaa atcataatgc cgactagggt cataagcttc aatggtaata
     6001 aaacgattgt attccaaata ccgtttcaaa atggctgcca tccttgaaaa gacaagaaaa
     6061 ccagatgtca aatccagacc aatccgcata tgctggccac cgttttcagc catatattcg
     6121 attaactgga gccattccca gagaatcttc ttatctaaat ctgtcccctg ttgaaaagca
     6181 ggtagagcat gaaaaatctc ctctgctgtc tctttaaaat catgttccat cagtaaatat
     6241 ggatgacgat tctctaactg gtacttgtag cgatcctgta aaatatagcc cttatagaga
     6301 tagacttgag cacaaagctg actgagttca taggtgacat ggtcctctgt ataatccccc
     6361 aatagttcct ccttcttcat ttcttgaatc aattgcgtca gtaaatctgc caactgccct
     6421 ccaaaaccaa gaatatactc catagtatga agaggaagaa tgcgatgaga taggagaaaa
     6481 gagaagaata tcatcatctc accatcctca actcctagtg gaatatgttg cccagcaaaa
     6541 aaggacggaa cctttctcag caaacgaaga taaaagatat tgtcaaaata ccctcgcatt
     6601 ttctcttcta tgacttgaaa ctgacaagca ttgacccgaa gacgttgttg actgatgtga
     6661 gcccagagaa ccaagtccaa tttctgcccc gcagacaaac ttgcaccgca gatttcctct
     6721 aaattggcaa tctcctgttt tctctctggt ttctgcatgt gaccttccca ttcctgactc
     6781 gaccagacct ttcggaaaag acagaaatag aaatagtgaa tctgatgctc tggacctcgc
     6841 caacggccat tttggatgga taaatcaaat tctgacaaaa tctgatttaa accagccaag
     6901 tgacgaccaa gcgtagcctc gctaatcacc aattcttgag ccagctgatg ggctaaaaac
     6961 tgttggtggt agagaagata aaccaaaatc tggtatttaa cagcactctc caaaaacaag
     7021 ctccgaatat ctctcccctt ggtagctgca ccgatagaca gacgcagatt ttcatcttct
     7081 gagtgaatag ccagctctaa gccactatcc aaagccttgt cattgagcag ggtgacatat
     7141 ttggttaggg ttgcttttga aaatcctgtt tcttccatta cagccttgac ggtcgtctga
     7201 gactcttgta atagaaagga aagtattgaa aattgaccac actcggcttt ctccatcaaa
     7261 tctcctaaat acatttgtta tccctttcat tttctacctt aagcatagca taaatctgac
     7321 aaatgctaaa ataatctgtt tctcttttta ttttcatgct gatttcctgg tccattatcc
     7381 tgaaaatcag taaacacacg gctccccctt tgggcatttt tatgctaaaa tagtagctat
     7441 ggataaaatt attaaaacta tatcagaaag cggagccttt cgtgcttttg tccttgatag
     7501 cactgaaacc gtccgcactg ctcaagaaaa acatcaaacc caagctagct caactgtagc
     7561 gcttggtcga actcttatcg ctagccagat tctcgcagcc aatgaaaaag gaaataccaa
     7621 acttacagtt aaggtgttgg gatctagctc tctaggtgct attatcaccg tcgctgatac
     7681 caaggggaac gtcaaaggct atgttcaaaa tcctggtgtt gacatcaaaa agactgcgac
     7741 tggtgaagtc ctagtcggac cttttgttgg aaatggtcaa ttcctcgtta tcacagacta
     7801 cggtactgga aatccttaca actctataac tcccctcatc tctggagaaa tcggtgaaga
     7861 ccttgccttt taccttactg aaagccaaca aacgccttca gcggtcggcc tcaatgtcct
     7921 tttggacgag gaagacaagg tcaaggttgc aggtggtttc ctagttcaag tcttgccagg
     7981 agccaagaaa gaagagattg ctcgctttga aaaacgcatc caagaaatgc cagctatctc
     8041 tactcttctc gaaagcgacg accatatcga agccctcctc aaggctatct acggggacga
     8101 agcctacaag cgtctttctg aagaagaaat ccgtttccaa tgtgactgta gccatgaacg
     8161 ctttatgaac gctcttgcca gccttccaag ctcagactta caggaaatga aagaggaaga
     8221 ccacggggca gaaatcactt gtcaattctg ccaaactact tacaactttg atgaaaagga
     8281 cctggaggaa ctcattcgtg acaaatctta atacaccttt tatgattggc aatattgaga
     8341 ttcccaatcg taccgtttta gcgcctatgg ctggcgtgac caactcagcc tttcgtacta
     8401 tcgcaaagga gctcggagct ggactcgttg taatggaaat ggtctctgac aagggaatcc
     8461 aatacaacaa cgaaaaaacc ctgcacatgc ttcatatcga tgagggcgaa aaccctgtct
     8521 ctatccaact ttttggtagc gatgaagaca gcctagcacg cgcagcagaa ttcatccaag
     8581 aaaacaccaa gaccgatatc gtcgatatca acatgggctg ccctgtcaac aaaatcgtga
     8641 agaacgaagc tggtgctatg tggctcaagg atccagacaa gatttactcc atcatcaaca
     8701 aggtccagtc tgtccttgat atcccactta ctgtcaaaat gcgtaccggc tgggcggacc
     8761 catctcttgc agtagaaaat gctctcgctg ctgaagctgc aggtgtttct gccctcgcca
     8821 tgcatggccg tacccgtgaa caaatgtata ctggccacgc agaccttgag accctttaca
     8881 aggttgccca agctctaacc aagattccat tcatcgccaa cggtgatatc cgtactgtcc
     8941 aagaagccaa gcaacgcatc gaagaagttg gtgctgacgc agtcatgatt ggccgagctg
     9001 ccatgggaaa tccttacctc ttcaaccaaa tcaaccatta ctttgaaaca ggagaaatcc
     9061 tacctgattt gacctttgaa gacaagatga agatcgccta cgaacacttg aaacgattga
     9121 ttaacctcaa aggagaaaac gtcgcagttc gtgaattccg cggtctcgct cctcactatc
     9181 tccgtggaac atctggcgct gccaaactcc gtggagccat ttcgcaagcc agcaccctgg
     9241 cagagattga aaccctcttg caattggaga aggcttaata gtttaaaacc cgtaactctc
     9301 ttaaagagcc tcttgaatgc cgccattctt tcctcatcaa aaaaactccg tagtctctag
     9361 cgctataaat ccggctagag attacagagt tattttttaa tctaaacttc ctacaagggt
     9421 atattatcta ctgaaaggat atggtatttg tagggaatac tttaaagagt tcttacagga
     9481 agtcagtatt aactagttat attaggttta gtttacccat tcaccattgg cattgactcc
     9541 atagccatct acagttgtgt tgactgcaag ggcacctgag ccattgacat agtaccattt
     9601 atctgatact ttgaaccatt ggcttgcttt catagcacct gatgcttcaa gatagtacca
     9661 ggtatctcca tctttcaccc aacctgtcgc catatcacca ttagcgttta ggta
//
LOCUS       DAVKEV010000059         9672 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVKEV010000059 DAVKEV010000000
VERSION     DAVKEV010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9672
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.059"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            180..2108
                     /gene="glgB"
                     /locus_tag="VWZ68_001863"
     CDS             180..2108
                     /gene="glgB"
                     /locus_tag="VWZ68_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEU9372847.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEYGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRKDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATNITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            2098..3240
                     /locus_tag="VWZ68_001864"
     CDS             2098..3240
                     /locus_tag="VWZ68_001864"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEU9372848.1"
                     /translation="MKNEMLALILAGGQGTRLAKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGIDSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLELGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            3230..4369
                     /gene="glgD"
                     /locus_tag="VWZ68_001865"
     CDS             3230..4369
                     /gene="glgD"
                     /locus_tag="VWZ68_001865"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEU9372849.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            4366..5799
                     /gene="glgA"
                     /locus_tag="VWZ68_001866"
     CDS             4366..5799
                     /gene="glgA"
                     /locus_tag="VWZ68_001866"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEU9372850.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            5858..6229
                     /locus_tag="VWZ68_001867"
     CDS             5858..6229
                     /locus_tag="VWZ68_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEU9372851.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVPGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            6269..6502
                     /locus_tag="VWZ68_001868"
     CDS             6269..6502
                     /locus_tag="VWZ68_001868"
                     /inference="COORDINATES: protein motif:HMM:NF019887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEU9372852.1"
                     /translation="MISPQVKKETLEKWRKKLKLSKERTVAIGDGVNNLLMLKSAELG
                     IAFCSKEMLKKEIPHHVDKRDFLEVLPLIDCLE"
     gene            6511..7627
                     /locus_tag="VWZ68_001869"
                     /pseudo
     CDS             6511..7627
                     /locus_tag="VWZ68_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(7624..8070)
                     /locus_tag="VWZ68_001870"
     CDS             complement(7624..8070)
                     /locus_tag="VWZ68_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEU9372853.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            8234..9538
                     /gene="eno"
                     /locus_tag="VWZ68_001871"
     CDS             8234..9538
                     /gene="eno"
                     /locus_tag="VWZ68_001871"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEU9372854.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFLGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
BASE COUNT         2908 a         1725 c         2138 g         2901 t
ORIGIN      
        1 tagaaaaaga aaggtgtttt cgcaattttt tgaaaaaata ttgatttaca attgaacgag
       61 taagtgaact tgttgtagat tttcaaaata attaaagaag tatagtaatt tacttgaatc
      121 ttctctaaaa aggtagtata ataaaaacat agaaaacgct tacaggagaa agggagtata
      181 tggataatag agaagcatta aaaaccttta tgacgggtga aaatttttat ctccaacatt
      241 atctaggagc acatagggaa gaactaaatg gagagtatgg ctataccttc cgtgtttggg
      301 cacctaatgc tcaggctgtt cacttggttg gtgattttac caattggatt gaaaatcaga
      361 ttccaatggt aagaaaggac tttggggtct gggaagtctt taccaatatg gctcaagaag
      421 ggcatattta caaatatcat gtcacacgtc aaaatggtca tcaactgatg aagattgacc
      481 cttttgctgt caggtatgag gctcgtccag gaacaggggc aatcgtaaca gagcttcctg
      541 ataagaaatg gagggatgga ctttggctgg cacgaagaaa acgttggggc tttgctgaac
      601 gtcctgtcaa tatttacgag gttcatgctg gctcttggaa gagaaatcct gatggcagtc
      661 cttatagttt tgcccaattg aaagatgaac tcattcctta cctagttgag atgaactata
      721 ctcatattga gtttatgccc ttgatgtccc acccactagg tttgagttgg gggtaccagc
      781 ttatgggtta cttcgcttta gagcatgcct atggtagacc agaggagttt caagattttg
      841 tcgaggagtg tcatacccat aatattgggg ttattgtgga ctgggtacca ggtcacttta
      901 ccatcaatga tgatgcctta gcctattatg atgggacacc gacttttgaa taccaagacc
      961 ataataaggc tcataaccat ggttggggtg cccttaattt tgaccttgga aaaaatgaag
     1021 tccagtcctt cttaatttct tgcattaagc attggattga tgtctatcat ttggatggta
     1081 ttcgtgtgga tgctgttagc aacatgctct atttggacta tgatgatgct ccatggacac
     1141 ctaataaaga tggcggaaat ctcaactatg aaggttatta tttccttcag cgcttgaatg
     1201 aggttattaa gttagaatat ccagatgtga tgatgattgc agaagaaagt tcgtctgcga
     1261 ccaatattac gggaatgaaa gagattggtg gtctaggatt tgactacaaa tggaacatgg
     1321 gctggatgaa tgatatcctc cgtttctacg aagaagatcc gatctatcgt aagtatgact
     1381 ttaacctggt gactttcagc tttatgtatg ttttcaagga gaattatctc ttgccattct
     1441 cgcacgatga agtggttcat ggcaagaaga gtatgatgca taagatgtgg ggagatcgtt
     1501 acaatcaatt cgcaggcttg cgcaatctct atacgtacca aatttgtcac cctggtaaga
     1561 aattgctctt catgggtagc gaatacggtc aattcctaga atggaaatct gaagaacagt
     1621 tggaatggtc taacctagaa gacccaatga atgctaagat gaagtatttc acttctcagc
     1681 taaaccagtt ttacaaagat catcgctgtc tgtgggaaat tgataccagc tatgatggta
     1741 ttgaaatcat tgatgcggat aatcgagacc agagtgttct ttcctttatt cgtaagggta
     1801 aaaagggaga aatgttagtc tgtatcttta atatggtacc tgttgagcgg aaagatttta
     1861 caatcggact acccgttgca ggaatttacg aagaagtatg gaatactgag ttggaagagt
     1921 ggggaggcgt ttggaaagaa cataatcaaa ctgttcaaac gcaagaagga ctatggaaag
     1981 attatgagca gaccttaacc tttaccctac cggctatggg agcaagtgta tggaaaatca
     2041 aacgtcgctt gaaatctact aaaaccgtca caaataaaaa ccaaaaagga gtagaaaatg
     2101 aaaaatgaaa tgttagcttt gattcttgct ggtgggcaag gaactcgtct cgctaaactc
     2161 actcaaagca tcgcaaaacc agctgtgcaa tttggtgggc gctaccgtat cattgacttt
     2221 gccctatcaa actgtgccaa ctcagggatt cacaatgttg gggtcgttac acagtatcaa
     2281 ccacttgctc tcaacaacca tattgggaat ggttcaagct ggggactaga cggtattgat
     2341 tcaggtgtct ctattcttca accttattct gcaagtgaag gaaatcgttg gtttgagggg
     2401 actagtcacg ctatttacca aaatatcgac tatatcgaca gtgtcaatcc tgagtatgtc
     2461 ttgattttgt ctggggatca catctacaaa atggactatg atgatatgct ccagtctcat
     2521 aaggataata atgccagctt gacagtagca gttttagacg tccctcttaa agaagcaagc
     2581 cgttttggta tcatgaacac agatgctaac aatcgtattg ttgaatttga agaaaaacca
     2641 gctcaaccta aatctacaaa agcttctatg ggaatctaca tttttgattg gcaacgcctt
     2701 cgtaatatgt tagtcgctgc tgaaaagagc aaggttggca tgtcagactt tggtaaaaat
     2761 gtcattccaa attaccttga gttaggtgaa agtgtttatg cttacgaatt tagtggttat
     2821 tggaaagatg ttggtactat tgagtcactt tgggaagcga acatggagta tatttctcca
     2881 gaaaatgcct tggatagtcg taaccgtcaa tggaagattt actcaagaaa cttgatttca
     2941 ccaccaaact tcctcggggc aaatgctcat gtggaagact cattagttgt agacggatgt
     3001 ttcgttgatg gaactgttaa acattctatc ctttcaacag gcgcgcaagt tcgcgaagga
     3061 gcggaagtcc ttgattcagt tatcatgagt ggagctatca ttggtcaagg agctaagatt
     3121 aaacgtgcca ttattggtga aggtgcgatt atttctgacg gtgtcgaaat tgatggaaca
     3181 gatgaagtac aagttgtagg atataatgaa gtagtggggg tagcaacaga tgaagattga
     3241 taaatattct gccattttag gaaatacagt tggttttcac aatatgtcga cattgacgga
     3301 ccaccgtcca gtagcaagtt tgccatttgg tgggaaatat cgtttgattg atttcccact
     3361 ttcaagcctt gctaatgcag gtgttcgtag tgtctttggt attttccagc aggataatat
     3421 cagctcagta tttgaccata ttcgttcagg acgcgagtgg ggcttatcaa cccttcttag
     3481 ccattactat ctaggaattt acaatacccg tgtagaaagt agtacagttg gaaaagaata
     3541 ctaccaacag cttcttactt atttgaaacg ttctggctca aaccaaacgg ttgccctcaa
     3601 ctgcgatgtt cttattaaca ttgatttgaa ccaagttttc cacctacata gtacaacaaa
     3661 agagcctatc actgtagttt ataaaaaact agctaagaaa gatatttcag aagtaaatgc
     3721 aatcttggat gtagatgaaa cagaccatgt tctttctcat aaactctttg atagcaagtc
     3781 aacagctgaa acgttcaata tgtctacaga tatctttgtc gttgatacac cttggttgat
     3841 tgaacacttg gaagaagaag ctaaaaaaga acatccagag aaattgcgct atgttttacg
     3901 ggatttggct gtaaaagagg gagctttcgc ctacgagtac acgggctatc tagccaatat
     3961 tcactctgtt aaatcttatt atcaagcgaa tatcgatatg cttgaatcac aaaaattcta
     4021 ttctcttttc tcaccaaacc aaaagattta tacaaaggtc aaaaacgaag agccaactta
     4081 ctatgctaat acatctaagg taagcacttc tcagtttgcc tctggtagta ttattgaagg
     4141 tcaagtagct aattctgttc tatcacgtaa tattcatgtc cataaggata gcttggttaa
     4201 agatagcctg ctcttccctc gtgttgttat tggagaaggg gctcaggtcg aatatgctat
     4261 cttggacaaa ggggttgaag ttgagcctgg tgttgtgatt cgaggaactg cagaacatcc
     4321 agttgtggtt aagaaaggtg ctaaagtaac agaggatatt cattcatgaa aattttattt
     4381 gtagcagcag agggtgcacc cttttcaaaa acaggtggtt tgggagacgt cattggcgct
     4441 cttccaaaat cactggtaaa agctgggcac gaagttgcag tgattttacc ctactatgat
     4501 atggtagagg ctaaatttgg aaatcagatt gaagatgtgc ttcattttga ggtgagcgtt
     4561 ggttggcgca gacagtattg tggaattaag aaaacagtat taaatggtgt aaccttctac
     4621 tttattgaca atcaatatta tttcttccgt ggtcatgttt acggtgattt tgatgacgga
     4681 gaacgctttg cctttttcca actggctgcc attgaggcta tggaaaggat tgactttatt
     4741 cctgatcttc tccatgttca tgactaccat acagctatga ttcctttctt gttgaaggaa
     4801 aaataccgtt ggattcaagc ctatgaggac attgaaacag ttttaaccat tcataattta
     4861 gaattccaag gacaattttc agaaggaatg ttgggtgatt tgtttggagt tggctttgaa
     4921 cgttacgctg atggcaccct tcgatggaac aactgtctga actggatgaa ggcaggtatt
     4981 ctctatgcga accgtgtttc aaccgtttca cctagctatg ctcatgaaat tatgactagt
     5041 cagtttggat gtaatttgga tcagattctt aaaatggagt ctggtaaagt atctggtatc
     5101 gtgaatggga ttgatgctga tctttataat cctcagacgg atgctctttt agactatcat
     5161 ttcaatcagg aagatttgtc tgggaaagcc aaaaataagg caaaattgca agaaagagtt
     5221 ggcttgcctg ttagagcaga cgttccactg gtgggaattg tttctcgttt gacacgtcaa
     5281 aaaggttttg atgtggtggt cgaaagtctt caccatatct tgcaagaaga tgttcagatt
     5341 gttcttttgg gaactggcga tccagccttt gaaggagctt tctcatggtt tgctcagatt
     5401 tacccagaca agctatcaac aaatatcact tttgatgtca aacttgctca ggaaatctac
     5461 gctgcttgtg acctcttcct catgccaagt cgttttgaac cgtgtggctt gtctcaaatg
     5521 atggctatgc gttatggaac cttgccattg gtccatgaag ttggaggctt gcgagataca
     5581 gttcgcgctt tcaatccaat cgaaggaagc ggtactggct ttagctttga caatctatct
     5641 ccttattggt taaattggac tttccaaaca gcattggact tgtatagaaa ccatccagac
     5701 atttggagaa acctacaaaa acaagctatg gagagtgact tctcatggga tacagcctgc
     5761 aagtcatacc ttgacttgta ccatagttta gttaattaat agataaaatc gtatgatgac
     5821 ttcatacgat ttttaggctg tttagagagg agaactgatg tctcaagtaa aaggcttgtg
     5881 tgttttggat gtagatggaa ccttaatcct agaagaagtg attgatcttt tagggagaga
     5941 ggcaggtcat gaggcggaaa tttcgcagat tacaagtcga gcaatgcgag gagagttggt
     6001 ctttgaaagc agtttaagaa aaagagtgtc cttgttggaa ggtcttccta ttttggtctt
     6061 tgataacgtc ttcaactcaa ttcatctatc gctaaatgtc ccagagttca tctctattct
     6121 ccaaaagaat ggcatcctag ttggtctggt gcctggtgga tttacaccaa tagttggaga
     6181 gattagcaaa atcccttggt attgcctatt tcactgccaa ccagcttgaa gtcaaagaag
     6241 gtttttaaca ggaaaattag ttggacaaat tataagtccc caggtcaaaa aagaaactct
     6301 ggaaaaatgg agaaagaaac taaaactttc taaagaaaga acggtggcaa tcggtgatgg
     6361 ggtcaataat ctattaatgt tgaagtcggc ggagttagga atcgcctttt gttccaaaga
     6421 aatgctcaaa aaagaaatac cacatcatgt tgacaagagg gattttttag aagttcttcc
     6481 tttgattgac tgtttagaat gagggaaaat atgaagattg taattgcacc ggattcgttt
     6541 aaggaaagct tgacagctca acaggtagct gaagcaataa aaagaggctt ccaacaatcg
     6601 atagcagatg tagaatatct cctctgccct gttggtgatg ggggagaagg tactgtagat
     6661 gctatccgac attctcttga cctaaaagaa aaatggatcc aagtgacaga cccttttgga
     6721 caaaaagaag ccatgcgcta ttttcaaaaa ggggaactgg cactatttga agtagctgac
     6781 ttggttggtc ttggaaaaat tccgctagag aaacgaaatc cacttcaaat ccaaacttgt
     6841 ggtattggag agttgattct ccatctcatt tctaaaggga ttaaagatat ttatatcggt
     6901 gttggtagca cggccagtaa tgatggagga ctggggattg ctgctggttt aggttatcaa
     6961 ttttatgata gggatggaaa tgtcttgcct gcttccagtc aatccttatt aaacttagct
     7021 tctgtttcaa cagaaaattg ctataaaatt cctgaaggtg ttcaaattca tattctagca
     7081 gatgtcgtga gtcccttatg tggtcatcaa ggtgcgactt acacttttgg caatcaaaaa
     7141 ggtctacatc cgactatgtt tgcagtcgta gatcaggcga tccaagattt ttatgaaaaa
     7201 ttctcacctg caacattaga aattaaagga gcaggagcag gtggaggcct tgctggtggt
     7261 ttgtgtgcct ttgctcaggc aagtatcgtg tctggaattg ataccttgct tggacttaat
     7321 caactttgat aagaaagttt cagatgctga cttgcttgtt gttggagaag gaagacttga
     7381 cagtcaaagc tttgctggga aagcgcctat aggtgttgca aaaagaaccc ctgttggagt
     7441 tcctgttatt gctatttgcg gtagtcttgc tgaagattta cctcccctac catttgaaaa
     7501 tatccaagct gtcttttcta ttttggagaa aagtgaacct ttagaagata gtttgaaaaa
     7561 tgccagtctc tatctggagc gcacggctgc caatattggg cacttattaa atatgtgcaa
     7621 gatttagcta aaccatttct tccataagga tgttttggct ggttcttcct ttttaacttc
     7681 ccaaagtttt ggaaaagcaa gtcgaaggtc tttttcttct acttgaactg gtgcattgct
     7741 atgaataacc aggccaaaag gagaagtaat atgctcttca gatactatgg tggcttgact
     7801 atcagtttct tttgcttctt ttaagtagaa aacttgctta tcaaattcga tagttggtga
     7861 aatcttcaca aatagtggct ctgctttttc ctgaaggttt tctaaaataa ataaaaagcc
     7921 tttttctaac tgagggctat ttgctgtgtc aatatctaca tatccaagaa ctctttcctc
     7981 aaaagtacca agatagcgtc tttgctcatc cggatttatt tttaacccac catgagcttt
     8041 ttcaagtaat tgttttgata aatctgtcat gaaaacagta tatcataaaa gttagaataa
     8101 aacagacaaa agaaagcgat tactttataa atttaaggaa aagttgcaca aagataacgt
     8161 tttttcttga aaaaggaggg gttttaaggt attatagagg tgtaaaaaat ttaactcata
     8221 aggagagtaa aaaatgtcaa ttattactga tgtttacgct cgcgaagtcc tagactcacg
     8281 cggtaaccca acacttgaag tagaagttta cactgaatca ggtgctttcg gacgtggtat
     8341 ggttccatca ggagcttcta ctggtgaaca cgaagcagtt gaacttcgcg acggtgacaa
     8401 atctcgttac ggtggtcttg gtacacaaaa agctgttgac aacgtaaaca acatcattgc
     8461 tgaagctatc attggctacg atgtacgtga tcaacaagct attgaccgtg ctatgatcgc
     8521 acttgacggt actcctaaca aaggtaaatt gggtgcgaat gcaatcctcg gtgtgtctat
     8581 cgctgtagct cgtgctgctg ctgactacct tgaaatccca ctttacagct accttggtgg
     8641 attcaacact aaagttcttc caactccaat gatgaacatc atcaacggtg gttctcactc
     8701 tgacgctcca atcgctttcc aagagttcat gatcttgcca gttggtgcgc caacatttaa
     8761 agaagccctt cgttacggtg ctgaaatctt ccacgctctt aagaaaatcc ttaaatcacg
     8821 tggtttggaa actgccgtag gtgacgaagg tggattcgct cctcgtttcg aaggaactga
     8881 agatggtgtt gaaactatcc ttgctgcgat tgaagctgct ggatatgtac caggtaaaga
     8941 cgtatttctc ggatttgact gtgcttcatc agaattctac gataaagaac gtaaagttta
     9001 cgactacact aaatttgaag gcgaaggtgc tgctgttcgt acatctgcag aacaaatcga
     9061 ctaccttgaa gaattggtta acaaataccc aatcatcact attgaagatg gtatggatga
     9121 aaacgactgg gatggttgga aagctcttac tgaacgtctt ggtaagaaag tacaacttgt
     9181 tggtgacgac ttcttcgtaa caaacactga ctaccttgca cgtggtatcc aagaaggtgc
     9241 tgctaactca atccttatca aagttaacca aatcggtact cttactgaaa cttttgaagc
     9301 tatcgaaatg gctaaagaag ctggttacac tgctgttgta tcacaccgtt caggtgaaac
     9361 tgaagattca acaatcgctg atatcgcagt tgcaactaac gcaggacaaa tcaagactgg
     9421 ttcactttca cgtacagacc gtatcgctaa atacaaccaa ttgcttcgta tcgaagacca
     9481 acttggtgaa gtagctgaat atcgtggatt gaaatcattc tacaacctta aaaaataaaa
     9541 tagttcagtg aactatttta tcccgaacca tgaaattcaa aagttcggcc gttgatttaa
     9601 caacgtttct agcccctcgg attttatccg aagggctatt tttgtattta gagggcaaaa
     9661 aagggacaaa ac
//
LOCUS       DAVKEV010000060         9370 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVKEV010000060 DAVKEV010000000
VERSION     DAVKEV010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9370
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.060"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..175
                     /locus_tag="VWZ68_001872"
     CDS             <1..175
                     /locus_tag="VWZ68_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU9372855.1"
                     /translation="NRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDTSSSGVTL
                     ITGKNGTGKSTLL"
     gene            complement(541..1851)
                     /locus_tag="VWZ68_001873"
     CDS             complement(541..1851)
                     /locus_tag="VWZ68_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEU9372856.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALKLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2088..2960
                     /locus_tag="VWZ68_001874"
     CDS             2088..2960
                     /locus_tag="VWZ68_001874"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEU9372857.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            3091..3922
                     /locus_tag="VWZ68_001875"
                     /pseudo
     CDS             3091..3922
                     /locus_tag="VWZ68_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            4033..4959
                     /locus_tag="VWZ68_001876"
     CDS             4033..4959
                     /locus_tag="VWZ68_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU9372858.1"
                     /translation="MDLSQTMPSYAQVVSLYDDTSISVSNNETDKVLAGSLYTDTNEQ
                     GLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQFQTKIVRVINDE
                     DDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTEELQKNKKYTVLS
                     QQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIGVMKAVGYQ
                     NRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFELNLLSVLG
                     TLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            5136..6143
                     /gene="gap"
                     /locus_tag="VWZ68_001877"
     CDS             5136..6143
                     /gene="gap"
                     /locus_tag="VWZ68_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEU9372859.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(6210..7046)
                     /locus_tag="VWZ68_001878"
     CDS             complement(6210..7046)
                     /locus_tag="VWZ68_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU9372860.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWKEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            7172..9367
                     /locus_tag="VWZ68_001879"
     CDS             7172..9367
                     /locus_tag="VWZ68_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU9372861.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
BASE COUNT         2891 a         1649 c         2052 g         2778 t
ORIGIN      
        1 aaacagaacg gtttcttttg ctattagttc aaaaggagaa aaaatgaaag tagaaaatat
       61 ttcgtatagg gtggatcatc gtatattgtt tgataatatt tcttttgata cttcgagttc
      121 aggcgtgaca ttaattactg gtaaaaatgg tacaggaaag tcaactttac tatagtagat
      181 tgaaactaga atagtacaca tctacttcta aaatattgtt agaaatcgat ttgactatcc
      241 tgatctattt gtcctgttct tatttcattt cactacatct caaattgagt atgacgaagt
      301 gcgctcccat gtcctgggaa cgcactttct tcatattttt catattcttg aatccatcga
      361 taaagactat tgggatgaat ttttaaagtt gaactaatta tttttacagg atgaggttta
      421 cagcagagag tttgaaggct ttatcaaagg tttttcttgg cataatgact tttcctcgtt
      481 tccacttaat tttgtgtcta ctttattata ccaagtccac ccttaagtta gataatgaat
      541 ctaacttaag gaagctagaa ggatgagaat ccaggtggtc aagagtccca aacttaagct
      601 gatagggaca cccagaataa tttgcttttt gaaggcaaga ccgcgttcct ctatattggg
      661 aagtgagagt tgaatgagag aaccagctga tgaaaagggt gagatattag tagatagagc
      721 gccaataacg gtggctgttg tgagtaagtg aatatcaatc tgaggatttt gagcactgat
      781 gatagcaatg atgggaaaga gggctggagc tacaacggat agggtggaac taaagagtga
      841 catcactccg gctatcacac aaaagaacag aggtaaccag aaatgaggaa tggttgttgt
      901 catgaggtgc cctatcagtg tgactaaacc tgacttgacc gctagagaca ttagtaagct
      961 catgccgcag agcatgataa ttgtagccca gggaacctta gctaaaatgg cttcttgctt
     1021 ccctaatttg agctttaagg cgaggcagac catgagtatt gagacaaagc caatatcaaa
     1081 tgttttttga taagtagcta tccaggcgat gtttgggaaa atgagatgca acaagggaaa
     1141 aagccaaacc aaaaccatgc tgctgatcat gagcaaggtg gtttgtcttt gaaccttgct
     1201 gaggagtggt ggttggtcaa tagtcaagga tgagtttgtt cttcccttac tatagtgact
     1261 gtaacaggat aataaaagca agacgatgag tgggtagata atgctgacga taaagatatg
     1321 attgccaagt gaaaaagctt gctcttccca tcccatttgc ttaaacaggc cttgaaagac
     1381 aatgcctgag ctactggtta tcaaattagc ccctcctgaa gctccccaat tgacggcttg
     1441 agctccaatc aaagggtgtt tgtccgcttt ttgacagagg gtaatcgcta gaggacagca
     1501 aacggccata gtagtgaaaa atccagcacc taaagcagac aaaagggttg ccatcaggta
     1561 taaaatcatg tagagggcgt tagggtgggt gcgtgtgcgg tagagaatgt gttgagccaa
     1621 aacatcaaga gtaccgttag ttgttgcaac gttataaaag agagagacgc taaaaatggt
     1681 aaaaaagagt gaggttggcc aaaaatgaag aagttctttg gggcttaatc ccatgagagt
     1741 ggttgcgatg aggtaagaaa aagcaatagc cagcaggcca atattgattt tggtgcggta
     1801 accaattcca atggctagag caatggcgct aatcattatt aaatgaatca ttgaattgtc
     1861 ctttcagtta gaatatggaa ataggttggc aattttggcg ctcaaaagac cacctgtttc
     1921 ctattggtac ttgactatta tacacaaaaa aaatacaatt gtcttgacaa ttgtattgac
     1981 acttgttaga attaaaaatg aggtattcag gcttgtgatt tcctatggaa gttaatagta
     2041 attgcctcta gtgcttacaa gtgatattaa aaatagagga cttagtgatg tcaatcattt
     2101 caactgattt aacccctttt caaatagatg atacattgaa agcagccttg cgagaagatg
     2161 ttcattccga agattacagt accaatgcca tttttgatca tcatggccaa gctaaggtgt
     2221 cgctttttgc caaggaagct ggtgttttag cggggctaac cgtttttcaa agggttttta
     2281 ccctatttga tgccgaggtg accttccaga atcctcatca atttaaggat ggggatcgtt
     2341 tgactagtgg cgatttggtt ttagaaatca taggctcggt gagaagtctc ttaacatgtg
     2401 aacgcgttgc cttgaatttt ttacaacatt tatcagggat tgcttcgatg acagctgctt
     2461 atgtagaagc cttaggcgat gattgcatta aggtatttga tactcgaaaa actactccta
     2521 atttacgtct ttttgagaaa tatgccgtga gagttggcgg tggctataat catcgcttta
     2581 atttatcaga tgctatcatg ctaaaagaca atcacattgc ggcagtaggt agtgttcaaa
     2641 aggcaattgc tcaagcgcgt gcctatgccc cttttgtgaa aatggtcgag gtggaagtgg
     2701 aaagccttgc tgctgccgaa gaagctgcgg cggcgggtgc tgatattatc atgttggata
     2761 atatgtcatt ggaacagatt gaacaggcca ttaccctaat tgcaggacgt tctcggattg
     2821 aatgttctgg aaatattgat atgaccacta ttagccgttt tcgtggttta gcgattgatt
     2881 acgtctccag tggtagttta acccatagtg ctaagagtct tgatttttcc atgaaggggt
     2941 taacctacct tgatgtctaa gttgtaaaat aaactaactt tttaaaggat gtctttcctc
     3001 tagaacgagt tttatgtcag atagtttaaa cgcctcttca aatatagtaa aatgaaccaa
     3061 aaatagtaca caatgtggta taatcttttt atggcatatt caatagattt tcgtaaaaaa
     3121 gttctctctt attgtgagcg aacaggtagt ataacagaag catcacacgt tttccaaatc
     3181 tcacgtaata ccatttatgg ctggttaaag ctaaaagaga aaacaggaga gctaaaccac
     3241 caagtaaaag gaacaaaacc aagaaaggtt gatagagata gacttaaaaa ctatcttact
     3301 gacaatccag acgcttattt gactgaaata gcttctgaat ttggctgtca tccaactacc
     3361 atccactatg cactcaaagc tatgggctac actcgaaaaa aagaaccaca cctactatga
     3421 acaagaccca gaaaaagtag ccttatttct taagaatttt aatagtttaa agcacctatc
     3481 acctgtttag attgatgaaa caggatttga tacttatttt tatcgagaat atggtcgctc
     3541 tttaaaaggt cagttaagaa gaagatatca gaggatttct ttggttgcag gtctaacaaa
     3601 tgaatggtga gttaatcgct ccaatgactt acgaagagac gatgacgagc gacttttttg
     3661 aagcatggtt tcagaagttt ctcttaccaa cattaaccac accatcggtt attattatgg
     3721 ataatgcaag attccataga atgggtaagt tagaactctt gtgtgaagag tttgggcata
     3781 aacttttacc tcttcctccc tactcacctg agtacaatct attgagaaaa catgggctca
     3841 tatcaaaaag cacctcaaaa aggtattacc aagttgcaat accttttacg aggctttttt
     3901 atcctgctct tgtttcaatt gactatagtt cacggataca gttgggaaag aagctattaa
     3961 atatttggag agtccttttg ggatgaacat gtcaaatatt actatagatg ggcaagaaaa
     4021 gatgggcaag aaatggatct gagtcaaacg atgccttctt atgctcaagt agtgagtctt
     4081 tatgatgata caagtatctc tgttagtaat aatgagacgg acaaagtgtt ggctggctcc
     4141 ctctatactg atacaaatga acagggatta acgattccaa gcagtttact aaaaaattgg
     4201 aatgaacaga caggaaaaaa tttgacagct aatgatctta ttggcaaatc agtctcagcc
     4261 agcattgtag aaagtgctgc cgaaactagt aagattgctc aatttcaaac gaagattgta
     4321 cgtgtaatca atgatgaaga tgacatggag gacagcaaca gtttcatgct gtctcatcaa
     4381 atggaaacga ttttgaaaga ggctggattt acgaaagctg tatcttattt tatcttggaa
     4441 ctcaaagatc catcacagac aaaagtagta acagaagaat tacagaaaaa taagaagtat
     4501 actgtgcttt ctcaacagag agttcttgat attgtgatta cctttattcg tgttattcag
     4561 ggattattga ttgtgctttc atcacaagct attgtggtag cagcggttat gattggtatc
     4621 attatttaca tcaatatcat gcaacgttcc aaggaaatag gtgtcatgaa agcagttggt
     4681 tatcagaatc gtggtgtcaa aggaattttt atttacgagg ctatctggat tgtaggcatc
     4741 gccttgctgc tggcattttt ggttgcacaa ggggtgggaa gtttggcgaa tgcgattgta
     4801 agtcactttt acccatccat cactaaggtt tttgaattaa atcttttatc tgttttagga
     4861 actctagttt tcgctctatt acttggttat gtctcagcct acttcccggc gcgtaagatt
     4921 agtaaaatgg atcctgtaga atcgttacgc tatgaataat aagggattcc ttgatttaca
     4981 gtcttaaaaa gaaactcaca tagaaaaaca atggccatac ttgcaattca actcaaatag
     5041 ttgtataata ggtttgttga aaggtgattt gtagtgattc aagttactct tttcacaata
     5101 aaaatttcat gattttcata aggaggaaat cactaatggt agttaaagtt ggtattaacg
     5161 gtttcggacg tatcggtcgt cttgctttcc gtcgtatcca aaacgtagaa ggtgttgaag
     5221 ttacacgcat caacgacctt acagatccag ttatgcttgc acacttgttg aaatacgaca
     5281 caactcaagg tcgtttcgac ggtactgttg aagttaaaga aggtggattc gaagttaacg
     5341 gtaaattcgt taaagtttct gctgaacgtg atccagagca aatcgactgg gctactgacg
     5401 gtgtagaaat cgttcttgaa gctactggtt tctttgctaa gaaagaagca gctgaaaaac
     5461 accttaaagg tggagctaaa aaagttgtta tcactgctcc tggtggaaac gacgttaaaa
     5521 cagttgtatt caacactaac cacgacgttc ttgacggtac tgaaacagtt atctcaggtg
     5581 cttcatgtac tacaaactgc ttggctccaa tggctaaagc tcttcaagat aactttggtg
     5641 ttgttgaagg attgatgact actatccacg cttacactgg tgaccaaatg atccttgacg
     5701 gaccacaccg tggtggtgac cttcgccgtg ctcgcgctgg tgctgcaaac atcgttccta
     5761 actcaactgg tgctgctaaa gctatcggtc ttgtaatccc agaattgaac ggtaaacttg
     5821 acggatctgc acaacgcgtt ccaactccaa ctggatcagt tactgaattg gtagcagttc
     5881 ttgaaaagaa cgttactgtt gatgaagtga acgcagctat gaaagcagct tcaaacgaat
     5941 catacggtta cacagaagat ccaatcgtat cttcagatat cgtaggtatg tcttacggtt
     6001 cattgtttga cgcaactcaa actaaagttc ttgacgttga cggtaaacaa ttggttaaag
     6061 ttgtatcatg gtacgacaac gaaatgtcat acactgcaca acttgttcgt actcttgaat
     6121 acttcgcaaa aattgctaaa taattcttga gttgatagaa agcaaggctt tgtggtcttg
     6181 ctttttatat ggaaaaatgg atgacacgat catccattct tttttaattc tttttcaaat
     6241 gtatttgaaa gggtagtgaa agttagcttc tctaaagtaa gtgggtgggt aaaggaaagt
     6301 cggaaggcat gaagcataag ccggcttgtc tttgatttac tattatagag agggtctccc
     6361 aggataggaa gattatgatg cgaaaggtgc acacgaatct gatgggttcg ccctgtcttt
     6421 agcttgcaat gagccaagga agtcttgttt gagaattgct ttaatctgct tacatgcgtt
     6481 tcagcatatt gcccattttt tgcatcaact attctttttc tacgatcatg gcgatcacgt
     6541 ccaattttgt ctctgaaaac aagttctttt ctgttgatat ttccatcaac tagagcccaa
     6601 tattctctag aaatctcttt tttctccaat aagcgattga gaatgggcag gataaaagga
     6661 tttttggcaa agagaactaa gccactggtt tccatgtcca gacgatgaac gacatagcag
     6721 gtttggccaa cataggtact gacatggtta agaagggcaa tttcgtttgg ttgattacca
     6781 tgcgttttca tcccctctgg tttgtttaca ataatcaagt gttgatcttg ataaacttcc
     6841 tgcactaagt ctgggttgcc ccaagggatc gtcttttggg aataatcttc ctcgtcaaaa
     6901 gtcaactggc aaacatctcc aggatttacg atttccttcc agtggacttc ttcttgattt
     6961 atcaaaatat gtttcttgat tctcaaaaaa tgacggattt ttctagggat gaggagttgt
     7021 tcctcaagta attgctttac tgtcatttga ggtagagagg cgggtaatgt aaatgtgaat
     7081 tgcatacaga tattgtaaca aaaaaagccc tatttggata ggaaatagct aaattcttgt
     7141 cttcctatga tgaagatgat aaaataaacg catgaaatta gataaattat ttgagaaatt
     7201 tctttctctt tttaaaaaag aaacaagtga actagaggac tctgattcta ctatcttacg
     7261 tcgctctcgt agtgatcgaa aaaaattagc ccaagtaggt ccgattcgaa aattctggcg
     7321 tcgttatcat ctaacaaaga ttatccttat actaggtttg agtgcaggct tgctagttgg
     7381 aatctatttg tttgctgtag ccaagtcgac caatgtcaat gatttgcaaa atgccttgaa
     7441 aactcggact cttatttttg accgtgaaga aaaagaggct ggtgccttgt ctggtcaaaa
     7501 gggaacctat gttgagctga ctgacatcag taaaaacttg cagaatgctg ttattgcgac
     7561 agaagaccgt tctttctata aaaatgacgg gattaactat ggccgttttt tcttggctat
     7621 tgtcactgct ggacgttcag gtggtggctc taccattacc caacagctgg ctaaaaacgc
     7681 ctatttatcg caggatcaaa ctgttgagag aaaagcgaaa gaatttttcc ttgccttaga
     7741 attaagcaaa aaatatagta aggagcaaat tctaaccatg taccttaaca acgcttattt
     7801 tggaaatggt gtgtggggtg tagaagatgc gagtaagaaa tactttggag tttctgcatc
     7861 agaagtgagt ctggatcaag ctgcgactct ggcagggatg ctcaaggggc cggaactgta
     7921 taatcccttg aattccgtag aagattctac taatcggcgc gatactgtct tgcagaatat
     7981 ggttgcagca ggatatattg ataaaaacca agaaaccgaa gctgctgaag ttgatatgac
     8041 ttcgcaattg cacgataagt atgaaggaaa aatctcagat taccgttacc cctcttattt
     8101 tgatgcggtg gttaatgaag ctgtttccaa gtataatcta acagaggaag agattgtcaa
     8161 taatggctac cgcatttaca cagagctgga ccaaaactac caagcaaata tgcagattgt
     8221 ttatgaaaac acatcgctat ttccgagggc agaggatgga acgtttgctc aatcaggaag
     8281 tgtagctctc gaaccgaaaa cagggggagt tcgtggagtt gtcggtcaag ttgctgacaa
     8341 tgataaaact ggattccgga atttcaacta tgcaacccaa tcaaagcgta gtcctggttc
     8401 tacaattaag cctttagttg tttatacgcc agcagttgaa gcaggctggg ctttgaataa
     8461 gcagttggat aaccatacca tgcagtatga cagctataag gttgataact atgcagggat
     8521 caaaacgagt cgagaagttc ctatgtatca agccttggca gaatcgctta atctacctgc
     8581 tgttgccact gttaatgatt tgggtgtcga taaggctttt gaggcaggcg aaaaattcgg
     8641 actcaacatg gaaaaggtcg accgtgttct tggtgtcgcc ttgggaagcg gtgttgaaac
     8701 caaccctctt caaatggctc aagcatacgc tgcctttgca aatgaaggtt taatgcctga
     8761 agctcatttt attagtagaa ttgaaaatgc tagtggacaa gttattgcga gtcataaaaa
     8821 ttcacaaaaa cgggtgattg ataagtctgt agctgacaag atgaccagta tgatgttggg
     8881 gactttcacc aacggtaccg gtattagttc atcgcctgca gactatatta tggcagggaa
     8941 aactggaaca actgaagcag ttttcaatcc ggagtacaca agtgaccagt gggtaattgg
     9001 ttatactccg gatgtagtga ttagccactg gcttggcttt ccgaccactg atgaaaatca
     9061 ctatctagct ggctctactt caaacggtgc agctcatgtc tttagaaaca ttgccaatac
     9121 cattttacct tatacgccag gaagtacctt tacggttgaa aatgcttata agcaaaatgg
     9181 aattgcacca gccaatacaa aaagacaagt acaaaccaat gataatagcc agacagatga
     9241 taatttgtct gatattcgag ggcgtgcgca aagtctagta gatgaggcta gccgggctat
     9301 ctcagatgcg aagattaagg aaaaggctca aacaatatgg gattcgatag tcaatctatt
     9361 tcgctaagat
//
LOCUS       DAVKEV010000061         9021 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVKEV010000061 DAVKEV010000000
VERSION     DAVKEV010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9021
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.061"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(298..1146)
                     /gene="dprA"
                     /locus_tag="VWZ68_001880"
     CDS             complement(298..1146)
                     /gene="dprA"
                     /locus_tag="VWZ68_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEU9372862.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLLTSGQDV
                     LAEFEF"
     gene            complement(1242..1931)
                     /locus_tag="VWZ68_001881"
     CDS             complement(1242..1931)
                     /locus_tag="VWZ68_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEU9372863.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(1943..2821)
                     /locus_tag="VWZ68_001882"
     CDS             complement(1943..2821)
                     /locus_tag="VWZ68_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEU9372864.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2811..3680)
                     /gene="licA"
                     /locus_tag="VWZ68_001883"
     CDS             complement(2811..3680)
                     /gene="licA"
                     /locus_tag="VWZ68_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEU9372865.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            complement(3697..4719)
                     /locus_tag="VWZ68_001884"
     CDS             complement(3697..4719)
                     /locus_tag="VWZ68_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU9372866.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4724..5431)
                     /locus_tag="VWZ68_001885"
     CDS             complement(4724..5431)
                     /locus_tag="VWZ68_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEU9372867.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGNRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5767..7254
                     /gene="tacF"
                     /locus_tag="VWZ68_001886"
     CDS             5767..7254
                     /gene="tacF"
                     /locus_tag="VWZ68_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEU9372868.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7264..8067
                     /locus_tag="VWZ68_001887"
     CDS             7264..8067
                     /locus_tag="VWZ68_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU9372869.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8069..8878
                     /locus_tag="VWZ68_001888"
     CDS             8069..8878
                     /locus_tag="VWZ68_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU9372870.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEKENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
BASE COUNT         2837 a         1813 c         1525 g         2846 t
ORIGIN      
        1 aaagcgcaaa ctaggaagct agccacaggt tgctcaaagc actgctttga ggttgtagat
       61 aagactgacg aactcagctc aaaatactgt tttgaggttg cagatggaag ctgacgtagt
      121 ttgaagagat tttcgaagag tattatatga gaaaaatcct ctactctact aatccactta
      181 gaaaaaacgc atattagcaa gtgttaaaaa cttgctaata tgcgttttat tatggaaatg
      241 ttgggttcat tttctcttaa aattgatttt ttcttagaat tctagcttag gtcattttta
      301 aaattcaaat tccgcaagaa catcttgccc actggtgagc aattttgctc cttcttgaat
      361 caaatgatgg caaccgtctg atagtccatc taaaatgcta ccaggaatag caaagacatc
      421 gcgtccttct tccattgctc gctcacacgt aatgagacta cctgaacgca tcttagcctc
      481 tgctacaatc acaccacgac aaagtccagc aatgatgcga ttacgggcag gaaaatgaaa
      541 tttcagaggt tgttcgccag gtccatattc acttagaacc agatggtcat tgccgatgta
      601 gtcttgcaag cgtttattgg ctttaggata aaacacatcc agtcctgttc caatcactgc
      661 aatggttttt ccgccattct gaagagctgc catatgagct gctgtgtcaa tgcccttggc
      721 cagaccactg acaataacca gttcattttc caagccttga atgacttttt caactgactt
      781 agctccctgt ttgctacaag cacgactgcc cacgaccgct accttcggga atttcaggag
      841 gtcaagattt cccttgtaaa ataaaagtac aggcgcatca tatatttcac tcaaatccca
      901 aggataacag tcatctaaaa tagagaaaga tggaaatttt tgaaactctt tcgacaaatg
      961 cgcatcgtct atctgaaaat aacgttccat aaaaacggct ggattacggc aacctgatat
     1021 atctgcaata tcacccaaca aaagctcctg atcaacattt tcaccgtatt ctagcacttt
     1081 caaaatctgt tgattggtca aacctgattt ttttaactta tagatttcat agtttgtgat
     1141 tttcataaat aactccattt ctttttctac tcatctatct attcgtaaaa gttcgtaaaa
     1201 aatcaaaaaa catccgacta ttttgtcaga tgttggaatc tttaattttc gtttttaaga
     1261 atttcttcta atttacgata gtcttggaca ctatcgatct cataaatgct attgccttct
     1321 aattcttcaa catagacatc tagctctttg atattatcct taaccatatt gtcccaatag
     1381 agatcaacaa attcaccact tgcataagcc ttgtcgataa agctgacaat cttttctgca
     1441 gttggagcat cccagaagga tacaccacta aggatgcgac ctgccttgct atcaacaata
     1501 atgtcttgaa ccttgtagtc atctccatag accaagaacc attcgttggt acaatcttca
     1561 cgataaacac taaaataagt cgaacgtgtc aaatcattgc ggaacatatt tttaaagaga
     1621 taattgtcag catcaataac atagctgttg gccaattctt cttttacaag atagagagag
     1681 taaaagttat tgtagtcagc gtatttatca ttgaaaacga ggcgaacacc gtatttttct
     1741 tttaagtaat cgaattgttc tttaagataa ccaacaatga tgatgatgtc attgattcct
     1801 ttttctttga gaaactcaat ttggtattca atcaaaggtt tttgattaac ctgaaccaag
     1861 gctttagggg tattttcagt cataggacgc aagcgagttc ccaatcccgc tgctaagata
     1921 atggctttca cacgaatctc ctttattctt taataataat ataaactcca gcaatgacga
     1981 caagtgacgt cataatggtc agcatatcta gcggtgcacc caaaaaaaca actgcaaaca
     2041 agaccgtcca tactacatag ctcacgttca agcctgtagc cttggctggt tgcaagcgat
     2101 tgatagcgat ataataagcc aagtaggaaa tcatatcaaa ggctgcaaaa acaatcatga
     2161 gacctagcaa ttgtccattg gctactgcag taaatgactg atgagagaag agcacaatca
     2221 caagatagga caagaacgaa gtcacttgac ggattaagag ggcttcgatt tcactcagtt
     2281 cactttccat agcaaaggag ctaagaacac tctcacttcc ccatgcaata gcacaaacca
     2341 aagcacagag aatcccaatg tagaaggaat taacctgttc aaccttatag gtctgggcaa
     2401 taatccctcc aataatcaag acaatcccaa atacagtatt tttcgaaatc ttgtgcttca
     2461 aaaagaagaa agccaataga actgaaatcg cagggtaaat agccgataca gatgaagcta
     2521 aagaacttcc gatatactta actgcataaa gattggcctg cataccgata gggcctgcta
     2581 gcaaggctcc gatgataaca ctgacattgc gaatatttaa gaaaattgag aggcgaactt
     2641 tcccttcttt taccaagaga aaagctagta agataaagat gctcaaaaaa tcatgagctg
     2701 cagccaccac aaagggtgac aaatctgtaa aaatcgaaaa gatataagca ctaaccgtta
     2761 gacccaagcc ccagaaaata cctgagagaa ggccaaaagg aactccgttt ttacttttca
     2821 tctgaacctc cataagaagc caaaccttta acagctcttt ggtaacgatt cacaccatag
     2881 tcaccaaaat cttcaccttg ctcttcctta tagacagtcc atagactcca aatagtatct
     2941 tgtaaaattt tataaatagc aatcttttca tgagaaaccg gtgtttggtc actctcatag
     3001 tgagataaga aagtttcttc ctcttgggaa gtgaattcag actctaaaaa gagggcagcc
     3061 aaatcccaca ttggatcatt cattgatgaa tattcccagt caatcaaata aagtcgtcct
     3121 tgaggtgatt cgataaagtt ttcaggcacc aaatcgatat gacaagattt tctgtcaaca
     3181 cctaagtcag ccagtctttt ctctaaggag aagactgcat ttctaacaga ttcatagttg
     3241 gcataaggaa tttgttcttc aatcaaggat tcgtattttt tgatttcttc aaaaggagca
     3301 aattctcctc ttaattcctt agcagacgta tgaatagttt gtaatattgg agcaattttg
     3361 tcgaacttgg tcttgattga cgttgaatca agcgtaatcg cagattcgat atactcattt
     3421 actttgatac cagcttcaat atcaaaaaga taatttttta catctaagcc taaatccttt
     3481 agtagttcaa gattgtactt ttcatcttgt cgattgataa gcttttctgt ccctttacca
     3541 aagaatttaa caatgtattg cttatttgtt gttttggcca aatagttttg attggtcatt
     3601 ccacccagtt gttcaacact gaggacttcc tcttcttgac taagtaagga agaaattttt
     3661 tctttaatga ttttctccac aattaacctc cagtacttat acttcccact taaacactgt
     3721 tttaaaggct gtgtttaaat cggttgcaaa gacacgatga atatctttaa tttctcttac
     3781 aggttcttct agataaagga tatttttaag acgattggca aatttcttga cttccatcat
     3841 ttggatagca tttttaaaat caatgcgacc agaacgagat gacccaacca aaatcaagcc
     3901 cttttctaag gcatcgcgag tattgagatt gactttatat tcgctaactc ccatcatgag
     3961 aatcgttccc tgaggacgaa tgtagcgaat caagtcatta atagctggtc cagtaccatc
     4021 accaccacaa cattcaaaag catggtcaaa ggccaactct tcaggaatat tatccgtaat
     4081 atagcattct ttggcaaatg agaagagttc caacttttcc caatgacgac caataaccac
     4141 aatctctgat tctggcaaag tatagttgat aatattggca accacaaaag ctaaacttcc
     4201 atctccaata acggcgatcc gctcccgctt gctatgagca agagtcaata gacgattcat
     4261 agcgtgcatg cccacactga caaactctgt aatggctgca accgtatctt caatagcatc
     4321 ataagccacc acacgatctt tagggagaga aacaaactct ctcataaagc catcaaatcc
     4381 actagacaag aaatgggtcc ctgtcatgta gttttcatag aattcttcat cactctgcat
     4441 aggagactga ttgggaatca tgacaacttt ttgaccaacc tcgtaggttc cggtcgggtc
     4501 agaaatgacg gttccacatg actcgtgaat cattgccatt ggaagctttt tattcaaaat
     4561 cttgggatca cgttttccct gatagtaacg ctgatccgca tgacagacag ccatgtagtt
     4621 gggacggata aggatatgat tctcttggtc aatagcctct tcctgatatt tgacattgat
     4681 aaacttaggc ttagttagtt gataaatttg attaatcatt ttactagtct ttctcaatca
     4741 tactttttgc aatcttcaaa tctgttacgg ttgtaatctt cagatttgag tattcacctt
     4801 tggccaaggc cacatctttt cctttgatca caaagatttt acatgcatct gtcaagattt
     4861 ccttctcttc atcagaaaga gatccataaa ggtccatgaa gtccttgcaa cggaatgttt
     4921 gaggtgtttg tccttgataa aggtgagcac gatttggaat atctgtaata aattgaccat
     4981 tggtactttc aacgatagta tcaaccgctt ctaccactgt gtccactgcg tcatgatttt
     5041 gggcaagttg gatattgtcc tgaatcatgc gaagtgtaat aaatggacga acagaatcgt
     5101 gggtaacaac gatatcctct ggagtaagcg gacgataagc atcaatggct tcaatgattt
     5161 tcttaatact tgtattgcgg tcagcaccac cctttgtaat gatgatacgt tccttataaa
     5221 gaggaagata tttatctaca agatcttctg catgagaaac ccagtctcca tgaacaccaa
     5281 ctacaatttt ttcaatactt ggctccaaga caaatttttc aattgtatga atcaaaatag
     5341 gtcgattacc tagctctaaa aattgttttg gcaagttact gatccccatg cgtgtgccag
     5401 ttccaccggc aagaattcct gcataaatca tctattttct cctttgtctt actaaaaaaa
     5461 cttattctct ctattatacc acaatctagt cctatcataa aagaaatact ggtcctcccc
     5521 ttctagaata ggagaattat gcagttctat tattcaaaga aactagtcca tttctagtaa
     5581 tgactaggaa ttctgtagca attactaata aatggctgcg aaattttaga gtccttcaga
     5641 ataatatact ttccttaaag aaaacttaaa acttaagatt tgaaacttca aagtgattac
     5701 ttgacttact gcccttcatt tcttattagc taactttatg atataatgaa aaacgaggta
     5761 aattgaatga aaagtataaa attaaatgct ctatcttaca tgggaattcg tgtcttgaat
     5821 attatttttc ccatcctaac tggaacctat gtcgcgcgtg tcttggaccg aactgactat
     5881 ggttacttca actcagtcga cactattttg tcatttttct tgccctttgc aacttatggt
     5941 gtctataact acggtttaag ggctatcagt aatgtcaagg ataacaaaaa agatcttaac
     6001 agaacctttt ctagtctttt ttatttgtgc atcgcttgta cgattttgac cactgctgtc
     6061 tatatcctag cctatcctct cttctttatt gataatccaa tcgtcaaaaa ggtctacctt
     6121 gttatgggga ttcaactcat tgcccagatt ttttcaatcg aatgggtcaa tgaagctctg
     6181 gaaaattaca gttttctctt ttacaaaact gccttcatcc gtatcctgat gctggtctct
     6241 attttcttat ttgttaaaaa tgaacacgat attgttgtct atacacttgt gatgagttta
     6301 tcgacgctga ttaactacct gattagttat ttttggatta aaagagacat caaacttgtt
     6361 aagattcacc taagtgattt taaaccactc tttctccctc tgacagccat gttagtcttt
     6421 gccaatgcca atatgctctt cactttttta gatcgcctct tcctcgttaa aacagggatt
     6481 gatgtcaacg ttagttacta taccatagct cagcgaattg tgaccgttat agctggggtt
     6541 gtaacaggtg caattggagt gagtgtgcct cgtctcagtt actatctggg gaaaggagac
     6601 aaagaagcct atgtttctct ggttaataga ggtagtcgaa tctttaactt ctttatcatt
     6661 ccactgagtt ttggactcat ggttttagga ccaaatgcca tcctacttta cggtagtgaa
     6721 aaatatatcg gaggcggcat cttgacctct ctcttcgctt ttcgtacgat tatcctggcc
     6781 ttagatacca ttcttggttc ccaaattctc tttaccaatg gctatgaaaa acgtatcaca
     6841 gtctatacag tctttgctgg gctactcaat ttgggcttga atagtctcct ctttttcaac
     6901 catatcgtgg ttcctgaata ctacttactg acaactatgt tatcagagac ttctctactt
     6961 gttttctata ttattttcat ccatagaaaa caactcatcc acttgggaca tatctttagc
     7021 tatactgttc gatactctct cttttcactt tcctttgtag caatttattt cctgattaat
     7081 ttcgtgtatc ctgtggatat ggtcattaat ttgccatttt taattaatac tggtttgatt
     7141 gtcttgctat cagctatctc ttatattagt ctacttgtct tcacaaaaga tagcattttc
     7201 tatgaatttt taaaccatgt cctagcctta aaaaataaat tcaaaaaatc ataggagttt
     7261 aaaatgaaac aactaaccat tgaagatgcc aaacaaattg aattagaaat tttggattat
     7321 attgatactc tctgtaaaaa gcacaatatc aactatatta ttaactacgg tactctgatt
     7381 ggggcggttc gacatgaggg ctttatccct tgggacgacg atattgattt atccatgcct
     7441 agagaagact accaacgatt tattaacatt tttcaaaagg aaaaaagcaa gtataagctc
     7501 ctatccttag aaactgataa gaactacttt aacaacttta tcaagataac cgacagtacg
     7561 actaaaatta ttgatactcg aaatacaaaa acctatgagt ctggtatctt tatcgatatt
     7621 ttccctatag atcgctttga tgatcctaag gtcattgata cttgttataa actggaaagc
     7681 ttcaaactgc tgtctttcag taaacataaa aatattgtct ataaggatag ccttttaaaa
     7741 gattggatac gaacagcctt ttggttgctc cttcgaccgg tttctcctcg ttattttgca
     7801 aataaaatcg agaaagaaat tcaaaaatat agtcgtgaaa atgggcagta tatggctttt
     7861 attccttcaa aatttaagga aaaggaagtc ttcccaagtg gtacctttga taaaacaatc
     7921 gatttaccct ttgagaattt aagccttcct gcacctgaaa aatttgatac tattttgaca
     7981 caattttatg gagattatat gaccctacca ccagaagaaa aacgcttcta cagtcatgaa
     8041 tttcacgctt ataaattgga ggattaggat gcaatattta gaaaaaaaag aaattaaaga
     8101 aattcaacta gccctgctgg actatattga tgagacttgt aagaaacatg atattcctta
     8161 ttttctcagt tatggaacca tgcttggagc catccgccac aaaggtatga ttccttggga
     8221 tgatgatatt gatatttccc tttatcgtga ggattatgag cgtttactga agattattga
     8281 aaaagaaaat caccctcgct acaaggttct ttcctacgat acatcttctt ggtacttcca
     8341 taatttcgca tcgattttgg acacttctac tgttatagaa gaccatgtta agtacaagcg
     8401 tcatgatacc agccttttca tcgatgtctt cccaattgat cgatttacag acttgagcat
     8461 tgtcgacaag agctataagt atgtggccct tcgtcaacta gcttatatca aaaaatcacg
     8521 agcagttcac ggtgatagca aactaaaaga ttttcttaga ttatgtagct ggtacgctct
     8581 ccgatttgtc aatcctcgct acttttacaa gaaaattgat caactagtca aaaatgctgt
     8641 aaccaacact cctcaatatg aaggaggagt tgggatcggt aaggaaggga tgaaagaaat
     8701 cttcccagtt gataccttta aagaactgat tttaactgag tttgagggcc gtatgttgcc
     8761 tgttcccaaa aaatatgacc aatttttaac ccagatgtat ggcgattata tgacaccacc
     8821 atcaaaagaa atgcaagagt ggtatagtca tagcattaaa gcttatcgca aaaactgatt
     8881 gagggggatt atacaaacta ctaagataga ggttattcaa aaacataatt ttagtagaaa
     8941 atgaaatata tattcccaca ataaaacgca tcatatcaag gtttttgaaa aaccttgata
     9001 tgatgcgttt tataatttta a
//
LOCUS       DAVKEV010000062         8927 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVKEV010000062 DAVKEV010000000
VERSION     DAVKEV010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8927
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.062"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..564
                     /gene="rsmG"
                     /locus_tag="VWZ68_001889"
     CDS             <1..564
                     /gene="rsmG"
                     /locus_tag="VWZ68_001889"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEU9372871.1"
                     /translation="YLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPE
                     LDVTIIDSLNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVAR
                     MQVLSELTIPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPR
                     YITVVEKKKETPNKYPRKAGMPNKRPL"
     gene            818..2101
                     /locus_tag="VWZ68_001890"
     CDS             818..2101
                     /locus_tag="VWZ68_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEU9372872.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMLATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTSGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(2296..3867)
                     /gene="ffh"
                     /locus_tag="VWZ68_001891"
     CDS             complement(2296..3867)
                     /gene="ffh"
                     /locus_tag="VWZ68_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEU9372873.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGVGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(3879..4211)
                     /locus_tag="VWZ68_001892"
     CDS             complement(3879..4211)
                     /locus_tag="VWZ68_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEU9372874.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            complement(4301..4678)
                     /locus_tag="VWZ68_001893"
     CDS             complement(4301..4678)
                     /locus_tag="VWZ68_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEU9372875.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSRYQVDGQKIE
                     LAYQLQNQEGHPFASYQLEITWG"
     gene            4750..6054
                     /locus_tag="VWZ68_001894"
     CDS             4750..6054
                     /locus_tag="VWZ68_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU9372876.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            6067..6873
                     /gene="yidA"
                     /locus_tag="VWZ68_001895"
     CDS             6067..6873
                     /gene="yidA"
                     /locus_tag="VWZ68_001895"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEU9372877.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDEGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMADKEIVKCMFIDEPE
                     ILDATIEKIPAEFYERYSINKSAPFYLELLTKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(7084..8859)
                     /locus_tag="VWZ68_001896"
     CDS             complement(7084..8859)
                     /locus_tag="VWZ68_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4365 domain-containing protein"
                     /protein_id="HEU9372878.1"
                     /translation="MANNRKTETLGVSYLSTFIDKHELLQSYFESNDKTPVWDGEIHV
                     LKSPSEKKDEILGKVPVQIKTTRQKKDVLKSFSLDTRDLELYKPNGGVVLFVVWLNED
                     NGLRDIYYKSLPPLSIKNLLKKSKLKNKSTNRKKLSIEIFKLDEKKMYPMLVDFINNS
                     QKQYSFINVEGISVEDIPDDKTLKFYFYGQEKEEIFNYQEEHDLFIYYLDPITGIEIP
                     LENTIKIVETEEETDLIIKIGDYVFQDVKRHRFPDGSVQLHFGESFTMSFDIKKKQFK
                     FNYTRPDLLSKAIKCTQVFQELGKIGYFTLNGNKIELDERSIKDISSLDLEADIKGLL
                     KISNFMKKMGIQKDVDLSCFDKQSQRNLNILYSGLVLKKKVALNYNESKLLHLNIANI
                     HIITLYSFLSDKNGTMIDIFTETPWCREGETEDEDYLDISIFEVFEPNDWLKIDNCKI
                     DSVIASYQRLVDNKLKYEGADRTILKIVIAADMAEDKTKRELLLNWAQCLSDWNLKYS
                     KNCEMAIINDLQIKSRVRKLNSKETETLTNILVNSNDNYELCFGSSVLLKSKPQADLF
                     WNKLDNETKERYKDFPIYTLYMKLS"
BASE COUNT         2612 a         1957 c         1538 g         2820 t
ORIGIN      
        1 tatctcaaac atttttacga ttcgattgca cccattcttc aaggtttgat tcccaatgaa
       61 actatcaaac ttcttgatat cggggctggg gcaggatttc ctagtctacc aatgaaaatt
      121 ctctatccgg agttagatgt gaccattatt gattcactca ataagcgcat caacttccta
      181 caactcttgg ctcaagaact ggatttgaac ggagttcatt tctaccacgg acgtgccgaa
      241 gattttgccc aagacaagaa cttccgtgct caatatgatt ttgtaacagc tcgtgcggtt
      301 gcccgtatgc aggtcctatc tgaattgacc attccctacc ttaaggttgg tggaaaacta
      361 ttggcactca aggccagcaa tgcgcctgag gaattattag aagctaagaa tgccctcaat
      421 ctccttttta gtaaggtcga agacaatctc agctacgccc taccgaatag agatccgcgc
      481 tatatcacag tggtagaaaa gaaaaaagaa acaccaaata aatatccacg taaggctggt
      541 atgccaaata aacgcccact ttaaattttt tagtaaacaa atgtttacaa aatcagcctc
      601 gctcttttat ttctaggctc gggaaaaaat gatttacaaa atcatttttt tctgctatac
      661 tatcctaagc aaaggttttt aatgtcatcc cgtgaggtga cgaagacgca gaaatattta
      721 aaactcttta aaatctaaat tttaaagaag tcttactctg agggcctatt gctgtaaaat
      781 aatgggctct tttttgatgc ccaaaagtga ggtttatatg aaacaagaat caactgttga
      841 tttgttacta gacgttgacc aacgtccttc ggctggaaaa ggaattctcc ttagtttcca
      901 acacgttttc gccatgtttg gtgcgaccat cttggtacca ttgattttgg gaatgcctgt
      961 atctgttgcc ctttttgctt caggtgttgg aacactcatc tacatgcttg ctactggttt
     1021 taaagttcca gtttatctag gttcttcatt cgcctttatc acagctatgt cactggctat
     1081 gaaagaaatg gggggggatg tatctgctgc tcaaacaggg gttatcttga ctggtttggt
     1141 ctatgtcctt gttgctacca gcatccgatt tgtaggaaca aaatggattg ataaactctt
     1201 gccaccaatc attatcggtc ctatgatcat cgttatcggt cttggacttg caggttcagc
     1261 tgttaccaat gcaggtcttg tagcagacgg aaattggaaa aatgctctgg tagccgttgt
     1321 tactttccta attgctgcct ttatcaatac aaaaggaaaa ggcttcctac gaatcattcc
     1381 attcctcttt gccattatcg gtggttacct cttcgcacta actcttggtt tggttgactt
     1441 tacgcctgtc ctagaagcta actggtttga aattcctggt ttctacttgc catttagcac
     1501 aagtggtgcc tttaaagagt acaatcttta ctttggtcca gaagccatcg ctatcttgcc
     1561 aatcgctatc gtaacaattt ctgaacatat cggagaccat actgttttgg gtcaaatctg
     1621 tggccgtcaa ttcttaaaag aaccaggtct tcaccgtact cttattggtg acggtatcgc
     1681 aacttctgtt tctgccttcc ttggtggacc agccaataca acttacggag aaaatacagg
     1741 ggttatcggt atgactcgta tcgcttctgt ctcagttatc cgtaacgctg ccttcatcgc
     1801 gattgccctc agcttccttg gtaaattcac tgccttgatt tcaactattc caaacgctgt
     1861 acttggtggt atgtcaatcc ttctctatgg ggttatcgcc agcaatggtt tgaaagtctt
     1921 gattaaagaa cgtgttgatt tcgctcaaat gcgaaacctc atcatcgcaa gtgctatgtt
     1981 ggttcttgga cttggaggag ctatccttaa acttggtcca gttacacttt caggtactgc
     2041 cctttcagcc atgacaggaa tcatcttgaa cttgatcttg ccatacgaaa ataaagacta
     2101 agagtctaaa tacacctaat ccactcagac agctgagtgg atttttcgta tactataata
     2161 aaagtgtctt aacaaaatta ttaaaatcaa aaaacgtata atatcagata ttctaaaacc
     2221 ttgatactgt acgttttatc atagaaattt ttactttatt ttctcatcaa atgagatttg
     2281 catcaatctc ttgtcttact tgcgtttctt cttcgctttc ttcattttgt tagccatacg
     2341 tttcatggac tgtttcatgg caaattcacc aattttacct ttcaaaccga caccaaacat
     2401 ctggctcata tctggcattc ctgctcctcc gagagctgat aagtcaggca taccgccttg
     2461 tcccatcatt ccttcaaggg cagacatatc cattcctccc atatttggca tatttttagg
     2521 aaggttattt ggattaatcc ccatttgctt catcatttta ttcatatccc cagacataac
     2581 accctgcatg agctgtttag cctggttaaa gtccttgatg aatttattga cttcgacgaa
     2641 tgtatttcca gaaccagcag caatacgacg gcgacggctt ggatttaaca aatctgggtt
     2701 ttcacgctct tcaggtgtca tcgaagacac aatggcacgt ttacgagcaa tctggcgttc
     2761 atccaccttc atgttttgaa gggctggatt gttggccata cctggaatca tcttgagcaa
     2821 gtcttccatc ggccccatat tttgcacctg atctaattga tcgatgaaat cattaaaatc
     2881 aaaggtgttt tcgcgcatct tctcagccat ttcaagggct ttttgttcat cgtattcctg
     2941 agaagctttc tcaatcaaag tgagcatatc ccccatacca aggatacggc tagacatgcg
     3001 gtctgggtgg aaggtttcaa tgtccgtaat cttttcacct gtaccagtga acttgattgg
     3061 ttttccagta atgtgacgaa cagacagagc agcaccacca cgagtatcgc catcaatctt
     3121 ggtaaggatg accccagtca cttccaactg agcattaaac tcacgcgcaa cattggctgc
     3181 ttcctgacca atcatagcat caacgacaag caagatttca tttggttgag ccaatgcttt
     3241 cacatcacga agctcattca tgaggagctc atcaatctgc aaacgacccg cagtatcaat
     3301 caagacatag tcgttatgat tagtttgggc ttgctccaaa ccttgacgta caatctcaac
     3361 agctggtact tctgttccaa gtgcaaagac aggcacatca atctgttgtc ccaaggtctt
     3421 aagctggtca atggcagctg gacgataaat atccgccgca atcatcaaag gacgagcatt
     3481 ttcttctttc ttgagtttgt tggccaattt accagcaaag gttgttttac cagccccttg
     3541 taaaccaacc atcatgatga tggttggaat cttaggtgac ttgataattt ctgccgtatc
     3601 agaacctaaa acggctgtca gttcctcatc aacgatttta ataatctgtt gcgcaggatt
     3661 aagtgtatca atgacctcat gcccgactgc acgctcacga actttcttga taaagtcctt
     3721 tacaacaggc aaggcaacgt cggcctcgag caaggccaag cgaatttctt tggttgcctc
     3781 ttggacatca gattcagaga tttttccttt tttacgtaga tttttaaaga cgttctgcaa
     3841 acgttctgtt aaactttcaa atgccatttt tcttcctctt attctctatt atcaatgctt
     3901 gttaaaattt ctatctgctc ctgcagaaaa tcatccttgg gatagcgctc caagatttgg
     3961 tcaaaaatct gactacggac aatgtagtcc gagtacatgt gcaatttcat ctcataatct
     4021 tccagaatct tttctgttcg cttgatattg tcatagacag cctgacgact aacaccaaac
     4081 tcctcagcta tctcagcaag actgtaatca tcagcgtagt aaagctcgat ataattcatt
     4141 tgcttatctg tcaaaagcgc cgcataaaat tcaaagagcg cattcatacg attggttttt
     4201 tcgatttcca taacttttat tataccaaaa aatagcctaa tctaccacac tagggagcca
     4261 atccttgaag atagaaagta gatttgagaa aaacgagatc ctagccccaa gtaatttcca
     4321 attgatagct ggcaaaggga tgcccctctt gattttgtag ttgataagct agctcaatct
     4381 tttgcccatc tacttgataa cggctcgttt gaatgataaa ttcctgcatg cccatagggg
     4441 taggaatata ggccaaacta tcactatcct ttaaaaagcg cataatggtc ttgggattgg
     4501 aaaatcggct catcataagt tcttgaccat gaaatttaat cactactttt tccttttcct
     4561 cattatagaa aagcaggtag ctataatctc ctttttcatg cacttccaca tcataaagct
     4621 ggtcaatcac ttccaactgc tcatcaaact gaattgtatt tcgcatccga atcttcacat
     4681 caggccctct ttcttgtctc ttgtcctact attttaccaa aaagagcagg attttgctat
     4741 aatggtcata tgaacgaaaa agtattccgt gaccctgttc acaactacat ccatgtcaat
     4801 aatcaaatca tctatgactt gattaataca aaagaatttc agcgtttgcg ccggatcaaa
     4861 caactgggaa cttccagtta taccttccac ggtggagaac acagtcgctt ctctcactgt
     4921 ctaggagtct atgaaattgc acgacgcatc acagagattt tcgaagaaaa atatcctgag
     4981 gaatggaatc ctgccgagtc tctcttgacc atgaccgctg ctctcctaca cgaccttggg
     5041 catggtgcct actcccatac ttttgaaaat ctctttgata cagaccatga agccattact
     5101 caggagatta ttcaaaatcc tgagacagag attcaccaag tcctgctaca agtagcgccc
     5161 gattttccag agaaagttgc cagtgtcata gaccatacct atcctaacaa gcaggtcgtg
     5221 cagctcattt ctagtcagat tgacgcagat cgcatggact atctcttgcg cgactcctat
     5281 tttacaggag catcctatgg ggaatttgac ctgactcgaa tcctccgagt cattcgtcct
     5341 atcgaaaatg gtatcgcctt tcagcgcaat ggcatgcacg ccatcgaaga ctacgtcctc
     5401 agtcgctacc agatgtacat gcaggtttat ttccaccccg caacacgcgc catggaagtt
     5461 ctcctacaga atcttctcaa acgcgccaag gaactctatc ctgaggacaa ggatttcttt
     5521 gcccgaactt ctccacacct cctgcctttc ttcgaaaaaa atgtgacctt gactgactat
     5581 ctggctctgg atgatggtgt gatgaatacc tacttccaac tctggatgac cagtcctgac
     5641 aagattcttg cagatttatc gcatcgcttt gtcaaccgca aggtctttaa atccattacc
     5701 ttttcacaag aagaccaaga ccaactcgct agcatgagaa aattggttga ggacatcggc
     5761 tttgatcccg actactatac tgccattcat aagaactttg acctccctta tgatatttac
     5821 cgtcccgaat ctgaaaatcc aaggacacag attgagattt tacaaaaaaa tggagaactg
     5881 gcagaactct ctagcctgtc ccctatcgtc caatcccttg ctggaagtcg ccacggagat
     5941 aatcgctttt atttcccgaa agaaatgtta gaccaaaaca gcatcttcgc aagcatcacc
     6001 cagcaatttt tacacttgat tgagaacgat cattttaccc caaataaaaa ctaaaagagg
     6061 aaatttatga gtattaaact aatcgccgtc gatattgacg gaaccctagt caacagccaa
     6121 aaggaaatca ctcctgaagt cttttctgcc atccaagatg ccaaagaagc tggtgtcaaa
     6181 gtcgtgattg caactggccg ccctatcgca ggcgttgcca aacttctaga cgacttgcag
     6241 ttgagagacg agggggacta tgtggtaacc ttcaacggtg cccttgtcca agaaactgct
     6301 acaggacatg agattatcag cgaatccttg acttatgagg attatctaga tatggaattt
     6361 ctcagccgca agctcggtgt ccacatgcac gccattacca aggacggtat ctatactgcc
     6421 aatcgcaata tcggaaaata cactgtgcac gaatcaaccc tcgtcagcat gcctatcttc
     6481 taccgtacac ctgaagaaat ggctgacaag gaaattgtca aatgtatgtt catcgatgaa
     6541 ccagaaatcc tcgatgctac gattgaaaaa attccagcag aattttacga gcgctactcc
     6601 atcaacaaat ctgctccttt ctacctcgaa ctccttacaa agaatgtaga caagggttca
     6661 gccattactc acttggctga aaaactcgga ttgaccaaag atgaaaccat ggcaatcggt
     6721 gacgaagaaa atgaccgtgc catgctggaa gtcgttggaa accccgttgt catggaaaat
     6781 ggaaatccag aaatcaaaaa aatcgccaaa tacatcacta aaacaaatga cgaatccggc
     6841 gttgcccacg ccatccgaac atgggtactg taaaaggaaa gaatagacta aaaccgctca
     6901 gctgagcggt ttttgtatga atatatcaca atgagagtaa attaataaat ttaattgcag
     6961 ttgtacagtt acttaaatct tgagagtaca aaaaataggc attgctttct taatttgtgg
     7021 tactgaattg taataaatca ctctctattt ctatatgtta tctctttata atctctttta
     7081 attttacgat aatttcatat acaaagtata aataggaaag tccttatatc tttcttttgt
     7141 ctcattatcc agtttattcc aaaacaaatc agcttgtggt ttcgatttta atagcactga
     7201 tgaaccgaaa caaagttcat agttatcatt actatttact aaaatattag ttagtgtctc
     7261 tgtttctttg ctgtttaatt tacgaactct agattttatt tgaaggtcat ttattatagc
     7321 catctcacaa ttttttgagt attttaagtt ccagtcagaa agacattgcg cccaattaag
     7381 taacaactct cttttagtct tatcttctgc catgtctgca gcgataacta tttttaaaat
     7441 agtacggtca gcgccttcat atttcagctt attatctacc aatctttgat acgaggcaat
     7501 aactgaatca attttacaat tatcaatttt tagccaatcg tttggttcaa atacttcaaa
     7561 aattgaaatg tctaaataat cttcatcttc agtttctcct tcccggcacc aaggagtttc
     7621 agtaaaaatg tctatcatag ttccattttt atctgacaaa aaactatata aagttataat
     7681 gtggatgtta gcaatattta ggtgaagtaa tttcgattca ttataattta aagcaacttt
     7741 cttttttaag acaagacctg aataaagaat atttagattt ctttgagatt gtttatcaaa
     7801 gcaagataaa tcaacatctt tttgtatacc catttttttc ataaagttag aaatttttaa
     7861 caatcccttt atatcagcct ctaaatcaag tgaagaaata tcctttattg accgttcatc
     7921 taactctatt ttattaccat taagggtaaa atatccgatt tttcctagct cttgaaatac
     7981 ctgagtacac tttatagctt ttgacagcaa atccggccta gtatagttaa atttgaattg
     8041 tttcttcttt atgtcaaaag acattgtaaa gctttcacca aaatgaagct gtacactccc
     8101 atcaggaaaa cgatgtcttt ttacgtcttg aaaaacataa tcgcctattt ttataattaa
     8161 atccgtttct tcttcagttt ctacaatctt tattgtgttt tcaagaggta tttctatgcc
     8221 agttatagga tctaaataat aaataaagag atcatgttct tcctgatagt taaaaatttc
     8281 ttctttttcc tgaccataga agtagaactt tagagtttta tcatcaggaa tgtcctcaac
     8341 tgaaatacct tcgacattta tgaaactata ctgcttctga ctattgttta tgaaatccac
     8401 taacattgga tacatttttt tctcatccag tttaaaaatc tctatggaaa gtttcttcct
     8461 atttgtagat ttatttttta gtttactctt tttgagcaaa ttctttatag aaagaggagg
     8521 taatgactta tagtaaatat ctcttaaacc attatcctca ttcaaccaaa ctacaaataa
     8581 aactactcca ccatttggtt tatatagttc taaatctcta gtatctaatg agaaggattt
     8641 taacacatct tttttctgtc tagtagtttt aatctgaaca ggtactttac ctaatatttc
     8701 gtctttcttc tcactcggtg atttaagaac atgaatttct ccatcccata ctggagtttt
     8761 atcattactt tcaaaataag attgaagtaa ctcatgctta tctataaatg ttgaaagata
     8821 tgaaacacct aatgtctcag ttttcctatt attggccaaa tctgcacctc taaaataact
     8881 ctatatactt tatattatag cattaagaaa taaaaataca tagcatt
//
LOCUS       DAVKEV010000063         8718 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVKEV010000063 DAVKEV010000000
VERSION     DAVKEV010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8718
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.063"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..638)
                     /locus_tag="VWZ68_001897"
     CDS             complement(<1..638)
                     /locus_tag="VWZ68_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9372879.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSK"
     gene            complement(926..1888)
                     /gene="nrdF"
                     /locus_tag="VWZ68_001898"
     CDS             complement(926..1888)
                     /gene="nrdF"
                     /locus_tag="VWZ68_001898"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEU9372880.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(2076..4235)
                     /gene="nrdE"
                     /locus_tag="VWZ68_001899"
     CDS             complement(2076..4235)
                     /gene="nrdE"
                     /locus_tag="VWZ68_001899"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEU9372881.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWTELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(4316..4534)
                     /gene="nrdH"
                     /locus_tag="VWZ68_001900"
     CDS             complement(4316..4534)
                     /gene="nrdH"
                     /locus_tag="VWZ68_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEU9372882.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPEKLKQLA"
     gene            4885..5148
                     /locus_tag="VWZ68_001901"
     CDS             4885..5148
                     /locus_tag="VWZ68_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEU9372883.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            5154..6887
                     /gene="ptsP"
                     /locus_tag="VWZ68_001902"
     CDS             5154..6887
                     /gene="ptsP"
                     /locus_tag="VWZ68_001902"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEU9372884.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            7142..>8718
                     /locus_tag="VWZ68_001903"
     CDS             7142..>8718
                     /locus_tag="VWZ68_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU9372885.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWLPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEKRIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPS
                     NPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLG
                     AKKTDLPSSDREFYNKTYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKL
                     VDDILAFLAPIRHPERLG"
BASE COUNT         2693 a         1646 c         1820 g         2559 t
ORIGIN      
        1 aacttactat gatctgcgag taaatatttt ttattagaat tatttaaagc gatgcgttga
       61 gcctctccct cttcctcgct aaaagtagct agagctccgt tttgaatacc attacagcta
      121 acgaaagctt tagaaaattg gagattagag agattttgta gggtcaatgt gccaacaaaa
      181 gcacctgtaa tatcgcgata atttccacct atcaaaatca aatctgttaa ttttcgttcg
      241 cttaaaatca gaaaaacagg tagactgttg gttacgacgc ggatattgtc aataggcaac
      301 tcacgcgcaa aaaactctaa tgttgttcct ggtccaatga aaatagtttc tctttcttct
      361 actagactgc ctgcaaaatg ggctatttct tgtttttctg ccgtttggag ggcttgtttt
      421 tcaatatttg atcgctcatt agtcaaaagg gagttggttc gaagtttttc agctccacca
      481 tgcacacgaa tcagcaaatc tttatcagct aattcctgta aatagcgcct tgcagtcata
      541 tctgaaacgg ctatttcgtc cataatctgt ttaactgtta tggttccttt actatttact
      601 atctctaaaa ttttggttaa tttttcttgt ttgagcatat tatcacctcg tttcctacta
      661 ctatcttacc ataaacaaac tcatcattca aatacaaaaa caacaaaatg aaacaaaaac
      721 aaaaatatcg aagtttgttt tcaaaacttt cgatattttt gttgggttat tattttgttg
      781 tttctagttt actttttgat ggttaagagt ggtggagaat tatactcaat gaaaatcaaa
      841 gagcaaacta ggaagctagc cgcaggctgt acttgagtac ggcaaggcga agctgacgtg
      901 gtttgaattt gattttcgaa gagtattagt ccaaaccgta gttgtagtca tcatcttgca
      961 tggcttcaac ttcgccaaga aggtaaccat ttccgacttg agagaagaag tcatggttgg
     1021 aagttcctgt tgaaataccg ttcataacga ttgggttgac atcttcagct gaatctggga
     1081 aaagtggatc ttgtcccatg ttcatgagag ctttattggc attgtagcga aggaaggttt
     1141 taacctcttc agtccaacca acaccgtcat aaagactctc tgtgtagcct tcttcatttt
     1201 cataaagagt atagagtagg tcgtacatcc attctttgag tttttcttgc tcttcttcag
     1261 gtaattcatt gaaaccaagt tggaatttgt aaccaatgta ggttccgtga acagactcgt
     1321 cacgaataat caatttaatg atttctgcaa cgttggcaag tttgttgtta ccgagatagt
     1381 agaggggagt gaagaaacca gagtagaaga ggaaggtttc gaggaagacg ctggcaactt
     1441 tcttttcaag tgggctgccg tttaggtaga tttcgttgac aatctcagcc ttcttttgta
     1501 ggtaaggatt ggtattggtc cattcgaaaa tttcttcaat ctcagcctta gtattcaagg
     1561 tagaaaagat tgatgagtaa gatttagcgt ggacagattc cataaattgg atgttattga
     1621 aaacagcttc ctcatgtggt gtacggatgt ctgcgcgaag ggcttgaacc ccagtttcag
     1681 attgcatagt gtcaagaagg gttaaaccac caaaaacttt tccgaccaag tctttctctt
     1741 tgttagatag ctttctccag tcatccaagt cgtttgataa gggaatacgt gtatcgagcc
     1801 aaaattgctc cgtcagtttt tcccaagttg atttgtcgat gacatcttcg atggcattcc
     1861 agttaatggc tttgtagtaa gtttccattt aaaatctctt tctgtgttta gtattgcgaa
     1921 ctcacaatta tttctacttt accataattc tataggagta tcgcacaaaa agtcggaagc
     1981 ccgactttta aaatgttaca taaattatgt tatgacatag tagatttgat tttatcagtg
     2041 ctgcttaggg aaaaatagtg tttctatgct agaaactaaa tcacacagct ttcacattgg
     2101 ttggcgccga cttctccacc gtcatctgta aaggtacgga cgtagtagat agacttgatt
     2161 cccttgttaa aggcatagtt acgaaggatg gacaagtcac gtgtcgtttg tttattttcc
     2221 ctcttccatt cgtaaaggcc ttttggaatg tcactacgca tgaagagggt gagtgaaagt
     2281 ccttgatcca cgtgttcagt cgcagcagcg taaacatcga tgactttacg catatccata
     2341 tcgtaggcag aagtgtagta aggaatggtt tctgtagaca agccagcagc agggtagtag
     2401 attttaccaa ttttcttttc ctgacgttct tcaatacgtt gcgtaatcgg gtggatagaa
     2461 gcagaaacat cgttgatgta gctgatagaa ccatttggcg ctacagcaag gcgattttgg
     2521 tggtaaagac catcctcttg aaccttgtcg cgaagttcag tccaatcagc aacaccaggg
     2581 ataaaaacat ttttgaagag ttctttaaca cggtctgatg ttggaacaaa ttcaccagtt
     2641 acatacttgt caaagtaact tccgttagca tagtctgatt tttcaaagtt gtggaaggta
     2701 ataccacgtt cacgcgcaat attgtttgac tctaccaagg tccagtagtt cataagcata
     2761 aagtagatgc ttgtaaattc aacagactca ggtgaaccat attcaatgag ttgttgggca
     2821 aggtagctgt gcagtcccat ggcaccgaga ccaaaggtgt gggcttggct atttccatgg
     2881 tcaatcgttg gtacagctac gatatgtgaa ctatctgtaa cgaaagtaag ggcacgaacc
     2941 atagcacgga tagaacgacc aaaatcaggt gaagtcatca tgttaaccac gttggttgaa
     3001 cccaggttac atgaaacatc tgttcccatt tgaaggaatt cttgagcatc gttgatcaag
     3061 cttggttctt gaacttgaag aatctcagaa cacaagttac tcatgataat ctttccatcg
     3121 acaggatttg cacggttagc cgtatctatg ttgactacat aaggatagcc agactcttgt
     3181 tgcaatttag agatttcagt ttccaaatcc cgcgccttga tttttgtctt gcgaatattt
     3241 ggatttgcga ccaattcatc gtatttttca gtaatgtcga tgtaattgaa tggcacaccg
     3301 tattcttttt ctacagagta agggctgaag aggtacattt cttcattttt acgagccaat
     3361 tcgtagaatt tatcaggtac tacaacacca agtgatagag tcttgacacg tactttttca
     3421 tcagcgtttt ctttcttagt tgaaaggaaa gcgatgatat ctgggtgaaa gacgttgagg
     3481 tagacaacac cggcaccttg acgttgcccc aattggttgg agtaagagaa gctgtcttca
     3541 aaaagcttca taacaggaac gacacctgaa gcagctcctt catagccttt gataggtgca
     3601 ccagcttcac gaaggttgct gagggtaatt cccacaccac caccaatacg tgaaagttga
     3661 agagctgagt tgatagaacg tccgatagag ttcatatcat ccgtcacttg gattaggaaa
     3721 caagatacca actccccacg acgagcacgt ccagcattca agaaggaagg agtagcaggt
     3781 tggtagcgtt ggtggatgat ttcattggca atatcgattg caacagcttc attcccatca
     3841 gcgaaataaa gggcgttgaa gaagacacgg tcttccatat tttcaagata gtattcaccg
     3901 tcattagtct ttaaggcata ttgattgtaa aatttataag ctgccatgaa tgacttgaat
     3961 tggaagtttt ggtctttgat aaattgagcc aattcttcca agaactctgg acggtatttc
     4021 ttgataaagg ctgtttcgat gtagttgtgt tcaatgaggt aattgatttt gtctttgatt
     4081 gaatcaaaaa ccatagtgtt tggaactaca ttttctttaa agaaagcatc caaggcttcc
     4141 ttatctttat gaagcatgat ttgtccatta acaggacggt taatttcgtt attaagacgg
     4201 aagtaagtca cgtcttcaag atgttttaat cccataaaat ttcccttatc taattacaaa
     4261 agaaaggctt ctaagttagc cctaaaagca gtttcttctg gatgatgtac taagattatg
     4321 ctaattgttt cagtttttct ggttggaaac ctgaaaagac ttcagttggt gtttggataa
     4381 caggagctgc gctaaaaccg agctctttaa cttgatcgac gtactcaggt tgctcatcaa
     4441 gattgatttc acgataagag acattattac tgtccaagaa acgcttggtc attttacatt
     4501 ggacacaatt gtttttagaa taaacggtta ccattgtgta actcctcttc aaaatttaat
     4561 actatcttag tatatcagaa aataaaattt tgtcaatgat ttaaactaaa tatagtggtg
     4621 ttcttttgtt gtttttatat ataaacacaa tatatagtgt ttgtattgtg aaatagcaat
     4681 gattatccta taaattgttt ttgaagaaac tatatcctgt gttttgttat ctaggataga
     4741 agattttcag caagttatct gaaaggaaat tgaaggaaaa tccagaaaat gcttgaaaaa
     4801 aatcctagaa gatggtataa tactaaattg taagggttat cacatataac tcaaaaaaag
     4861 aaagaacaaa aggagagtca aactatggct tctaaagatt tccacgtagt ggcagaaaca
     4921 ggtattcacg cacgtccagc aacattgttg gtacaaactg ctagcaaatt tgcttcagat
     4981 atcactcttg agtacaaagg taaatcagtt aaccttaaat caattatggg tgttatgagt
     5041 cttggtgttg gtcaaggtgc tgacgtaact atctcagctg aaggtgcaga tgcagatgac
     5101 gctatcgctg caatctcaga aacaatggaa aaagaaggat tggcataagg gaaatgacag
     5161 aaatgcttaa aggaatcgca gcatctgacg gtgttgcagt tgcaaaagca tatctactcg
     5221 ttcagccgga tttgtcattt gagactatta cagtcgaaga tacaaacgca gaagaagctc
     5281 gccttgatgc cgctctacag gcatcacaag acgagctttc tgttattcgc gagaaagcag
     5341 taggtacgct cggtgaagaa gcagctcaag tttttgatgc tcacttaatg gttcttgctg
     5401 acccagaaat gatcagccaa atcaaggaaa ctatccgtgc gaagaaagtg aatgcagaag
     5461 caggtctgaa agaagttaca gatatgttta tcactatctt tgaaggcatg gaagacaacc
     5521 catacatgca agaacgcgca gcggatatcc gcgacgtgac aaaacgtgta ttggcaaacc
     5581 ttcttggtaa aaaattgcca aacccagctt ctatcaatga agaagtgatt gtgattgcgc
     5641 atgacttgac tccttcagat acagctcaat tggacaaaaa ctttgtaaaa gcttttgtaa
     5701 ccaacattgg tggacgtaca agccactcag ctatcatggc acgtacactt gaaattgctg
     5761 ctgtattagg tacaaacaac atcactgaaa tcgttaaaga cggtgacatc cttgctgtta
     5821 acgggatcac tggagaagtg attatcaacc cgacagatga acaagcggca gaatttaaag
     5881 cagctggtga agcctatgcg aaacaaaaag ctgaatgggc acttttgaaa gatgctcaaa
     5941 cagtgactgc tgacggtaaa cacttcgagt tggctgccaa tattggtact ccaaaagacg
     6001 ttgaaggtgt taacaacaac ggtgcagaag ctgttggact ttaccgtaca gagttcttgt
     6061 acatggattc tcaagacttc ccaactgaag atgagcagta tgaagcatac aaggctgttc
     6121 ttgaaggaat gaacggtaaa cctgttgtcg ttcgtacaat ggatatcggt ggagataagg
     6181 aacttcctta cttcgatatg cctcacgaaa tgaacccatt ccttggattc cgtgctcttc
     6241 gtatctctat ctctgagact ggagatgcta tgttccgcac acaaatccgt gctcttcttc
     6301 gtgcgtctgt tcacggtcaa ttgcgtatca tgttcccaat ggttgcgctc ttgaaagaat
     6361 tccgtgcagc gaaagcagtc tttgatgaag aaaaagcaaa ccttcttgct gaaggtgttg
     6421 cagttgcgga taacatccaa gttggtatca tgatcgagat tcctgcagcg gctatgcttg
     6481 cagaccaatt tgctaaagaa gttgacttct tctcaattgg tacaaacgac ttgatccaat
     6541 atacaatggc agcagaccgt atgaacgaac aagtttcata cctttaccaa ccatacaacc
     6601 catcaatcct acgcttgatt aacaatgtga tcaaagcagc tcacgctgaa ggtaaatggg
     6661 ctggtatgtg tggtgagatg gctggtgacc aacaagctgt tccacttctt gtcggaatgg
     6721 gcttggatga gttctctatg tcagcaacat ctgtacttcg tacacgcagc ttgatgaaga
     6781 aactcgacac agctaagatg gaagagtacg caaaccgtgc ccttacagaa tgctcaacaa
     6841 tggaagaagt tcttgaactt caaaaagaat acgttaattt tgattaatcg aaaagtccct
     6901 gcaactcagt tacagggact ttttttgata ttttaaaaag aattttcaag aaaatctttc
     6961 ttataaaaag tccaaccttg aaaaagtagt ggtcagaaca aaaaatactt aaatggttca
     7021 taaaattctt gacaagttgg agatttagga gtaaactatt aaccagttaa gtaatagaga
     7081 ggagtttctg caatttagaa atgaattgca actagaaata tcaaatagaa agagagtttc
     7141 gatgaaaatt aataagaaat accttgttgg ttctgcggca gctttgattt taagtgtttg
     7201 ttcttacgag ttgggactgt atcaagctag aacggttaag gaaaataatc gtgtttccta
     7261 tatagatgga aaacaagcga cgcaaaaaac ggagaatttg actcctgatg aggttagcaa
     7321 gcgtgaagga atcaatgctg agcaaatcgt catcaagata acagaccaag gctatgtcac
     7381 ttcacatggc gaccactatc attattacaa tggtaaggtt ccttatgatg cgattttcag
     7441 tgaagaatta ctcatgaaag atccaaacta taagctaaaa gatgaggata ttgttaatga
     7501 ggtcaagggt ggatatgtta tcaaggtaga tggaaaatac tatgtttacc ttaaggatgc
     7561 tgcccacgcg gataacgtcc gtacaaaaga ggaaatcaat cgacaaaaac aagaacatag
     7621 tcaacatcgt gaaggtggga ctccaagaaa cgatggtgct gttgccttgg cacgttcgca
     7681 aggacgctat actacagatg atggttatat ctttaatgct tctgatatca tagaggatac
     7741 tggtgatgct tatatcgttc ctcatggaga tcattaccat tacattccta agaatgagtt
     7801 atcagctagc gagttagctg ctgcagaagc cttcctatct ggtcggggaa atctgtcaaa
     7861 ttcaagaacc tatcgccgac aaaatagcga taacacttca agaacaaact ggctaccttc
     7921 tgtaagcaat ccaggaacta caaatactaa cacaagcaac aacagcaaca ctaacagtca
     7981 agcaagtcaa agtaatgaca ttgatagtct cttgaaacag ctctacaaac tgcctttgag
     8041 tcaacgccat gtagaatctg atggccttgt tttcgaccca gcgcaaatca caagtcgaac
     8101 cgccagaggt gtagctgtcc ctcatggtaa ccattaccac tttatccctt atgaacaaat
     8161 gtctgaattg gaaaaacgaa ttgctcgtat tattcccctt cgttatcgtt caaaccattg
     8221 ggtaccagat tcaagaccag aacaaccaag tccacaatcg actccggaac ctagtccaag
     8281 tctgcaacct gcaccaaatc ctcaaccagc tccaagcaat ccaattgatg agaaattggt
     8341 caaagaagct gttcgaaaag taggcgatgg ttatgtcttt gaggagaatg gagtttctcg
     8401 ttatatccca gccaaggatc tttcagcaga aacagcagca ggcattgata gcaaactggc
     8461 caagcaggaa agtttatcgc ataagctagg agctaagaaa actgacctcc catctagtga
     8521 tagagaattt tacaataaga cttatgactt actagcaaga attcaccaag atttacttga
     8581 taataaaggt cgacaagttg attttgaggc tttggataac ctgttggaac gactcaagga
     8641 tgtctcaagt gataaagtca agttagtgga tgatattctt gccttcttag ctccgattcg
     8701 tcatccagaa cgtttagg
//
LOCUS       DAVKEV010000064         8610 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVKEV010000064 DAVKEV010000000
VERSION     DAVKEV010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8610
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.064"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            72..1328
                     /locus_tag="VWZ68_001904"
     CDS             72..1328
                     /locus_tag="VWZ68_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU9372886.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKEPEKFFGL
                     IEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRN
                     FENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(1363..1785)
                     /gene="nusB"
                     /locus_tag="VWZ68_001905"
     CDS             complement(1363..1785)
                     /gene="nusB"
                     /locus_tag="VWZ68_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEU9372887.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREYT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(1778..2167)
                     /locus_tag="VWZ68_001906"
     CDS             complement(1778..2167)
                     /locus_tag="VWZ68_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU9372888.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            complement(2189..2749)
                     /gene="efp"
                     /locus_tag="VWZ68_001907"
     CDS             complement(2189..2749)
                     /gene="efp"
                     /locus_tag="VWZ68_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEU9372889.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            complement(2878..4320)
                     /gene="gatB"
                     /locus_tag="VWZ68_001908"
     CDS             complement(2878..4320)
                     /gene="gatB"
                     /locus_tag="VWZ68_001908"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEU9372890.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            complement(4320..5786)
                     /gene="gatA"
                     /locus_tag="VWZ68_001909"
     CDS             complement(4320..5786)
                     /gene="gatA"
                     /locus_tag="VWZ68_001909"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEU9372891.1"
                     /translation="MTFNDKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDTDNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSASVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILSAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            complement(5786..6088)
                     /gene="gatC"
                     /locus_tag="VWZ68_001910"
     CDS             complement(5786..6088)
                     /gene="gatC"
                     /locus_tag="VWZ68_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEU9372892.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            6301..7845
                     /locus_tag="VWZ68_001911"
     CDS             6301..7845
                     /locus_tag="VWZ68_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEU9372893.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            8100..8297
                     /locus_tag="VWZ68_001912"
     CDS             8100..8297
                     /locus_tag="VWZ68_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEU9372894.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            8408..8584
                     /locus_tag="VWZ68_001913"
     CDS             8408..8584
                     /locus_tag="VWZ68_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEU9372895.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
BASE COUNT         2459 a         1710 c         1904 g         2537 t
ORIGIN      
        1 ttttattgta gaaaaaaagt cccatatgac ctataatgaa aagcgacaaa accatcatta
       61 gaaagattca tatggaacaa ttacatttta tcacaaaact gctcgatatt aaagacccaa
      121 acatcaagat tctagatatc atcaatatgg atacccacaa agaaattatc gctaagctgg
      181 attatgaggc tccatcttgc cctgattgtg gaagtctaat gaagaaatat gactttcaaa
      241 aaccgtctaa gatcccttac ctcgaaacaa ctggtatgcc ttctagaatt ctccttagaa
      301 aacgccgttt caagtgctat cactgttcaa aaatgatggt tgctgagact cccctggtaa
      361 agaaaaatca ccaaatccct cgtatcatca accaaaaaat tgctcaaaag ttaattgaaa
      421 aaatttctat gactgatatt gcccatcagc tggccatttc aacttcaact gtcattcgca
      481 agctcaatga ctttcacttt gagcatgatt tttctcggct tccaaagatt atgtcttggg
      541 atgagtatgc cttcactaag ggaaagatga gtttcattgc gcaagatttt gataatctta
      601 atattatcac tgttcttgaa ggcagaacac aagctgtcat ccgaaatcac tttcttcgct
      661 acgatagagc cgttcgttgt caagtgaaaa tcattacgat ggatatgttt agtccttact
      721 atgacttggc taaacagctt tttccgtgtg ctaaaatcgt tctagatcgt ttccatatta
      781 tccaacatct cagccgtgcc atgagtcgtt ttcgtgttca aattatgaat cagtttgaac
      841 gaaaatctca tgaatacaag gctatcaagc gttactggaa actcatccaa caggatagtc
      901 gtaaattgag cgataaacgt ttttatcgcc ctacttttcg catgcactta acaaataaag
      961 aaattcttga caagatttta agctattcag aagacttgaa acaccactat cagatctatc
     1021 aactcttact ttttcacttt cagaataagg aaccggagaa atttttcgga ctcattgagg
     1081 acaatctgaa gcaggttcat cctatttttc agactgtctt taaaaccttc ctcaaagata
     1141 aagaaaagat tgtcaacgcc cttcaactac actattctaa tgccaaactg gaagcgacca
     1201 ataatctcat caaacttatc aagcgcaatg cctttggttt tcggaacttt gaaaacttca
     1261 aaaaacggat ttttatcgct ttgaacatca aaaaagaaag gacgaaattt gtcctttctc
     1321 gagcttagct tttcttcaac ccactacagt tgacaaagag ccttattgtt cttctgttac
     1381 aaactggctg agcagtccat tgataaaacg ggcagatttt tgatcggaga agtcctttgc
     1441 aagctcgata gcttcattaa cagcaaccag ctgaggagtg tcaaatgaag tgatttcaaa
     1501 gactcccaag cgaaggaggt ttctctccac gagcgttaag cgttcaatgg tccaacctgc
     1561 ttttaaatgc tgagtgattt gcttatctag ttcttccttt ttagcttgaa caccagaaac
     1621 gaggtctatc aaaaaggctg gaagttgtac atccgtatat tcacgatcat gagtataggc
     1681 gaaacgacaa gcagtttcga catccgtacc gaactcaagg ctcatgagag cttgaaaagc
     1741 gcatttacgg agttggcgtc tagattctaa tagtggacta gtcattgagg aagtcctcgt
     1801 caaatagatc tttcaattct ggttttggtg ttttatctgg gacgatacct gcaacgtgaa
     1861 tattgatagc agcgagttct acatcagcca tattacggac ggcatctttg acagctttct
     1921 ggatagcaac cgctacctta ggaactttta ctccgtactc aaggtagaga tagatatctg
     1981 ctgtgagttc ttcgtccacg tttttaagat aaatgccacg gccgagtgaa agttttgaaa
     2041 gggtatcaga cactgatctg tttgaaaaag agtgaacacc ctctaccttt gcagtagcga
     2101 tagcaatgat tttttcaagt acacgtgggg cgataacgat ttcgccaagt tgttcttcaa
     2161 ttcccataga atgacctctt tctagagatt aggcacgaga aacgtaagtt ccttctgcag
     2221 tgttgataac gagtttttgt cctgcttcga tgaagtctgg aacgtttacg acaagtccag
     2281 tttccatcgt tgctggttta ccagaacctg taacagtagc acctttgata gatggttgag
     2341 tttcagcaac tgtcaactca acagtagtag gaacggtgac accgatcact tcagttccgt
     2401 agaattggat tttcacatca gagttttcaa ggatgtaaag caattcgttt tcaacattga
     2461 ctacagggat ttcgtattgg tcgtaagttt ctgtattcat gaagtatgct gtgtcatcca
     2521 ttttgtacaa gtattgagct gggacagtct cgataatagc ttgttcaaat ttttcctctg
     2581 gacggtagct tgtgtcaaat gtagaaccag tacggacatc acgcaatttc atacgcatga
     2641 tcgtgtttcc tttacctggt ttgtggtgac tagcttccaa aacgcgaatc aatttgccgt
     2701 cagctgtttc aaaggtcata ccagctttta atttacttgc ttcaatcatg tttttacctc
     2761 tttaataaat attattactc ttcattttac cataaaatac tctggaaata aagccaaaat
     2821 agttattggg agttggtaga gaagaaaaaa ccaaccttag ggctggtttt gttctgtcta
     2881 gttttctttc aacttcgcca attcctgtgc aagtagttta agggcaactt gtgggttggc
     2941 ttggcctttg gttgccttca taaggaatcc tgtaaaggcc ttgtcggcgt tacgtttgcc
     3001 tgacttgaag tcggcaacag cagcttcgtt atcggcaaag acttggtgga tgattgggat
     3061 caagatagct ggatctgaaa tttgaaccat acctgctttt tccacgtatt cacgcgcgcc
     3121 accgccattt ttagctagat ggacaaagac tttcttggca atcttagatg aaatagtacc
     3181 gtcttcgatg atggtaatca tttcaaccaa gttttctggt gtcaattcga tttgttccag
     3241 tgttttacct tcagcattca agaactgagc gacttcccct tggagccagt tagagacttg
     3301 tttggcatca ccacctaggg caacagcttt ttcaaagaag tcagaagtga ctttattagc
     3361 agtcaactga ctagcatcgt agtctgataa accaaggtca gatacataac gcgcacgacg
     3421 ttcttttgga aactctggca actcagtccg catttcctca atccactcgt cagaaatttc
     3481 aaagaggggt aggtctggtt ctgggaagta gcggtagtca gcagcccctt ccttgacacg
     3541 catgaggatg gttgttttgt tagcttcatc gtaacggcgt gtttcttggc ggatttgacc
     3601 acctgagcga agaatttcag cctggcgttg gacttcgtat tcaagacctt tacgaacgtt
     3661 tgagaaggag ttgaggttct tcaattcagt cttggtaccg aatttttctt gaccataagg
     3721 acgaagggag atgttggcat ccacacgcat agaaccttct tccatcttaa cgtcagaaat
     3781 gccagcgtac tggataactt ccttgagggc tgtcagataa gcataggctt cttcaggaga
     3841 acgcatatct gcctcagata caatctcaat caagggaacc ccttggcggt tgaggtcaac
     3901 ataagagtag ccatctgtac catgggtgtt tttaccagcg tcttcctcta agtgggcacg
     3961 ttcgataccg attttcttgg tcgtaccgtc ttctagtttg acttcaatcc agccattata
     4021 tccgattggt tcatcaaatt gagaaatttg gtaggctttg gggttatcag gatagaagta
     4081 gttcttgcgg tcaaagtgca tctttttgtg gatgtccatg ttgagggcaa gagcagcctt
     4141 gataccggca tcaacaaccc ctttattgag aactggtaga actcctggga aagaccagtc
     4201 aattacgtta gtgttggcat tttggtcatt tccgaagtgg gcagaagtag gtgagaagat
     4261 ttttgaattg gtgttgagct ctacgtggac ttcaagtccg atgactgttt caaagttcat
     4321 tagttgtcac ctccaaaaat cacgggttgt tgtttgtggt agtctgttgt tgcttcaaaa
     4381 gcagcagcag cttggtaaat ggtttcctca gagtacttgg gaccaatcaa ttggagtccg
     4441 acaggtagac cttgagagaa tccagcagga atcgaaattc caggcagtcc tgccaagttt
     4501 acaggtatgg tcaagaggtc ggctaagtac atggcaactg ggtcatggtt gagagaatcc
     4561 aagtcatagg caacacttgg agcagttgga cccaaaatca aatcgtaatc cgcgaagact
     4621 ttttcgaaat cttgaatgat aagtgtacgg acctgtccag ccttcttgta gtaggcatcg
     4681 tagtaacctg atgaaagact gaaagtaccc agcatgatac gacgttttac ctcttcacca
     4741 aaaccttggc ttcggctgtt tacatagatt tcatcaaggt tggttgcatc ttctgcgcga
     4801 tagccgtaac ggataccgtc aaagcgttgc aagtttgatg aagcttctga tgaagcgatg
     4861 atgtagtata cggcaactcc gtatttagag tgaggaaggc tgacttcttc gacaatagca
     4921 ccaagttttt caaagtgttt agcggcactt agaatggttt ccttaacctc tgggttaatt
     4981 ccttcaccga ggtattcctt aggcaaagcg attttcatac ccttgatgtc ttggccgatt
     5041 tttgaagtaa agtcggcgat gcggacagaa gcagaagtag agtctttagc atcttcgctg
     5101 gcaatagcgt tgagcaagag ggcattttcc ttaacagtag gagcaaaagg tccaatctgg
     5161 tctaatgagc tgccaaaggc aatgagaccg aaacgtgaaa ctgttccgta ggttggtttg
     5221 agaccaacga ttccgttgaa ggcagcaggt tggcggatgg aaccaccagt atcagaacca
     5281 agtgacaagc gaacttgtcc tgaggctaca gctgcggcag aaccacttga tgacccacca
     5341 ggaaccttgc tgtggtccca agcgttttta gttgctccgt agtgtgaagt ttcacctgaa
     5401 ccacccatag caaattcgtc catgttggtc tttccaacga caatcatgcc cttggttttt
     5461 gcattggcaa cagctgtcgc atcaaagatt ggctcatagt tgtagagcat ttttgaggca
     5521 gcagttgtga gaataccgtc tgtagagatg ttatccttaa cagcaagtgg aattcctgaa
     5581 aggacattgt cagtatcaat tccagcttca tcaatggctt tagcttgaac aagagcttgc
     5641 tcctcagcga tggtgacaaa tgaattgagg gcttcctcac gagacttgat attttcaagt
     5701 gttgcttggg tcaattctgt tgcagaaatt tccttagaga caaggagatt gtgcaactct
     5761 tcaatagttt tatcgttaaa agtcattagg catctcctcc atcgtctagg atagctggca
     5821 ccttgatata gtagttgtct ttttcaggta cgtttttaaa caagcgatca cggtctgttc
     5881 cttcttcggc cacatcaggg cggagtacag tcttgcggtc agccatagtc gtagtaggtg
     5941 cgacaccagt tgtgtcaact tcgcccagca attcaaccat gtcaacaatc ttagacaagg
     6001 tggtcgcaaa ggcagcagtt tcttcttcag agaatcttaa ttttgaaaga ttggcaacgt
     6061 gtgttacctc ttcttgcgta attttcatct tgcatccttt cgtgaaatga tgatttttag
     6121 tctgttctat tttaccatat tttcctataa ataagggagg gggaagtgaa aagaaataga
     6181 aattgaaaaa aatgctaaaa tccgatataa tggagtgttg aaaggaatgg taaaatccaa
     6241 tgtaaaaatc attctcagct attgaaacaa gaaaaataga gaatcaaaga aagagaactt
     6301 atgaatattc aagaagaaat taagaaacgt cgtacctttg ccattatctc ccacccggac
     6361 gcggggaaaa caaccatcac tgagcagtta ctctactttg ggggtgagat tcgtgaggct
     6421 ggtacggtaa aagggaagaa aacagggact tttgctaaat ctgactggat ggatatcgag
     6481 aagcaacgtg ggatttctgt tacttcatct gttatgcaat ttgactacga cggcaagcgc
     6541 gtgaatatct tagacacgcc agggcacgag gacttctcag aagataccta tcgtaccttg
     6601 atggcggtgg atgctgcggt catggtcgtg gactctgcca aggggatcga ggctcaaacc
     6661 aagaaattgt ttgaggttgt gaaacatcgt ggcattccag tctttacctt tatgaacaag
     6721 ctggaccgtg acggtcgtga gcctttggat ctcttgcaag aattggaaga aatcttgggc
     6781 attgctagct accctatgaa ctggcctatc gggatgggga aagcctttga gggcttgtat
     6841 gacctctata accaacgttt agagctttat aaaggggatg agcgttttgc cagtctagaa
     6901 gacggggaca aactctttgg tagcaatcct ttctacgagc aagtcaagga tgacattgag
     6961 cttttaaatg aagctgggaa tgagttttca gaggaagcta ttctggctgg agaattgacg
     7021 cctgtctttt tcggttcagc cctgacaaac tttggtgtgc agaccttcct tgaaatcttc
     7081 ctcaagtttg ctccagaacc acatggtcac aagaaaacag acggtgaaat tgtggatcct
     7141 tatgacaagg atttctcagg ctttgtcttt aaaatccaag ccaacatgga tcctcgtcac
     7201 cgtgaccgta ttgcctttgt ccgtatcgta tcaggcgaat ttgagcgcgg catgagtgtc
     7261 aatctccctc gtactggtaa gggggctaaa ctatctaatg ttacccagtt tatggcggag
     7321 agtcgtgaga atgtgaccaa tgccgtggca ggtgatatta tcggggttta cgataccggt
     7381 acttatcagg ttggggatac cttgacggtt ggaaaaaaca agtttgaatt tgaaccactg
     7441 ccaaccttta ctcctgaaat tttcatgaaa gtttctgcta agaatgttat gaagcaaaaa
     7501 tccttccaca aggggattga gcaattggtg caagaaggag ccgttcagct ttataagaat
     7561 taccaaacag gtgagtacat gctgggagct gttggtcaac tccagtttga agtctttaaa
     7621 caccgtatgg aaggcgaata caatgcggaa gtggtcatga gcccaatggg taaaaagacc
     7681 gttcgttgga tcaagcctga ggacttggat gaacggatgt cgtcaagtcg caatatctta
     7741 gccaaagacc gttttgacca accagtcttt ctctttgaaa atgactttgc cctccgctgg
     7801 tttgcggaca agtatccaga cgtagagtta gaggagaaga tgtgactcag taccaacaat
     7861 tggaactaaa gttccaaatt gttggacgct agtcgctatt tggcgaacta gctaactgcc
     7921 tcactaacta cgtttggcaa atgaaatcga tttgtaaaac tccgtgtcgt aatgtaaaaa
     7981 ttgtaaaccg taatgggact tcatctaaaa tctccactgg tatggtttta cgaacgaata
     8041 ggcgaaaata atggttacgt agaaacatat gatgggaata aaaagaaatg agataaaaag
     8101 tgaaagaaga gaaaaaagcg attgtcttag gtgcagataa tgcttatatg gataaagttg
     8161 aaacaacaat aaaatctctt tgtgttcatc attataatct taagttttat gtttttaatg
     8221 atgaccttcc gcgagaatgg ttccaattga tggaaaaaag actagagact ttgaatagtg
     8281 agattgtgaa tgtttagatt gacagtaata ttctgaaagg ttatcgtctc ccctttgagg
     8341 gactttcata tgcggctttt ttaggtattt tattccaaag tatgtaagcg agtctcgtgt
     8401 actgtatttg gattcagata ttgttgtaag aaaatcgata gatgagctgt gggatttgga
     8461 cttgacggct atacccttag ctgcagttag agatgatttt tatacacata attttaattc
     8521 tggtgttctg ttaatcaacg atggcatgtg gagagcagaa aatgtcacgc aagacctgat
     8581 ttaagacaca aataaaaaat cttccaattc
//
LOCUS       DAVKEV010000065         8266 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVKEV010000065 DAVKEV010000000
VERSION     DAVKEV010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8266
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.065"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            146..793
                     /locus_tag="VWZ68_001914"
     CDS             146..793
                     /locus_tag="VWZ68_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEU9372896.1"
                     /translation="MVVGIAIASGYLNSHLDKFVDWGSWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWEASQE
                     GRPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
     gene            924..1337
                     /locus_tag="VWZ68_001915"
     CDS             924..1337
                     /locus_tag="VWZ68_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372897.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            1356..1541
                     /locus_tag="VWZ68_001916"
     CDS             1356..1541
                     /locus_tag="VWZ68_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372898.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRGLTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(1808..2251)
                     /locus_tag="VWZ68_001917"
     CDS             complement(1808..2251)
                     /locus_tag="VWZ68_001917"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEU9372899.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKRGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(2281..4503)
                     /locus_tag="VWZ68_001918"
     CDS             complement(2281..4503)
                     /locus_tag="VWZ68_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEU9372900.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYPSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            5519..6148
                     /locus_tag="VWZ68_001919"
     CDS             5519..6148
                     /locus_tag="VWZ68_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU9372901.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(6271..8163)
                     /gene="pepO"
                     /locus_tag="VWZ68_001920"
     CDS             complement(6271..8163)
                     /gene="pepO"
                     /locus_tag="VWZ68_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEU9372902.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         2242 a         1898 c         1588 g         2538 t
ORIGIN      
        1 ttattttcag ggttttattt ctatcatttt attttacttt catttggtgg gagaatattt
       61 gaaaaaaaga aaggtagttt aacctatgaa aaaatcacta aaaatttttg ctacatctaa
      121 atagtttgac ctcttcgggg ttgctttggt cgttgggatt gcgattgcat ctggttacct
      181 caactcacac ctcgataaat ttgtagactg gggatcatgg acagctcttg taccctttgg
      241 attgatttcc gtaaccaacg ttgggatttc catgttgtcc actcgtttca cggggaaatt
      301 aagcaaatgg ggaaattact ttggtattgt taataccatt ttgtccggtg ctattgatta
      361 tatccttgga aataaggcgg ccatcattac ctatcccgtc accttcctca tttatacctt
      421 tgctataaag aagtgggaag cttcgcaaga aggcagaccc aaccaaatga gccaaaaaca
      481 ggtaaaattg gcggccatca tcatttccat catcgccttc ctctttgcct ttgtgaccaa
      541 ctatatcgga tatgggggca agatgaatct ccttgcctac gtaacaacta ttgcctttgc
      601 actgtccctc attgccaatg ctttgaatgc attaaaacta acaactcagt ggggcttttg
      661 gttgatttac aatttcgttc agctgacaaa agctggtatt caaggaaact tcgccaatat
      721 cggtaaatac atcttttata tcctcaatgc aatcggagct ttatttgtct ggaatgatga
      781 agaagttaga taatagaagg aaactcaaat aaagaatact agccaactta agagaatctc
      841 ccttctgcta tttttatcat tttagttgta actcccattc ttttggagta gaatgaagtt
      901 agataaaaga gggaggtctt gtcatgaaaa aactctatag aatccatttt atagcaattg
      961 cagttattga tttgctacta tttgcatttt ttatcactag actcgagaca tcttttgagt
     1021 ggctcttgct ctctggttta attttcttcc ttgctcaagg actcctgcta tttctcttgg
     1081 tcgtccgact caaacatcaa ttcgctgaga tttatcctca aatcaataaa aagattcgct
     1141 tctactattt aggggttctc accattgatt ttctattttt tgttctctta gccttcatta
     1201 gttctcagcg tttttcatct cttatgccaa tcatcactgc ttgccattct actttttatt
     1261 atatgacagc tgactaccta agagaaaact atccagactt ttacgacaaa cacatctctt
     1321 tatgggagtg tctctaagga aaaggaggtt ttagcatgaa aaaaatcatc ttcatcaaaa
     1381 ccattcaact ccttgtcatt gatggaatca tgctggcatt tttgacattt aaaagggggc
     1441 ttacttggga ctggattttg atttatagcg gttggctcat tttctttcat cctgtgctat
     1501 tgacctatct ttcaaaccaa ctttgtgacc actttagtta actctattcc cagattagac
     1561 cgagattctg gcgttttgct ttacaaattc tcctatggga tagcctgatg attctctcct
     1621 tggtgtcttt aagtgatatt ccacttttcc ttcagggaac tctcctcatc ctaggacatc
     1681 tcatcccttc ctatcgcatc tgccaaagcc tgaaaagaga cttcccccaa gcatatcaag
     1741 aaccgatttc tttttggagt attttatgat agatgagaaa gaccaagccg actgggcttg
     1801 gtctttctta tctcttttta gtatctagga taatggtaac aggtccatta ttaaccagct
     1861 caacctgcat atctgctcca aagatgcctg tctgaacggg cacttcttgc gctaattttt
     1921 gattgaaagc atcatagaag tctgatgcca tatcaggttt agctgcccct gtaaaggctg
     1981 gacgattgcc tctcttagta tccgcaaaga gggtaaactg agaaatagag aggatttctc
     2041 cttcaatatc tttgacagac aggttcatct tgccttctgc gtctgaaaaa atccgcatat
     2101 tgaccagttt tctcacagca tagtccaaat cttcctcttg gtcctctggt ccaacaccaa
     2161 ccagcaataa aagtccctga ttgatttttc cctgaatctg gccttctata ctcacttggg
     2221 cttttttaac ccgttggata atgattttca taatagcctt tctagtaaga gctaggacaa
     2281 ctagccgttg gtccgtttga cagagtaaac ttctggcaca ctcttaattt tatcgacaac
     2341 cgtggtcagt gtagagaggt tggcaatacc gaaggacaca tggatattag caaacttcat
     2401 atccttggtt ggttgggcat tgaccgttga aatattcttg gttgtatttg aaagaacttg
     2461 cagtacatcg ttcaacagtc ctgtacggtt gagaccgtag atatcgatat gggccatata
     2521 ctccttattt gagctagggt actggtcttc ccattccaca tcaaggagac gttgctcgta
     2581 gttttcttgg gcacgcaggt tcatacagtc cacacggtga atagccacac cacgaccctt
     2641 ggtaatgtag ccaacaatat cgtcaccagg cacggggtta caacacttag caatccgcac
     2701 taggagacca gaagcacctt caataaccac tcccccctca tgcttgacct tgagggtttc
     2761 tttattttca accttgacct cgccaccttt gacaagctcc tctgcctcag ctttggcctt
     2821 ggcacgctct tcctcacggc gttccttttc agtcagacgg ttaaagacgg taatcgcacc
     2881 gatttcccca aaaccaatgg ccgcaaagag ggagtcttct gtcttgtaac tggtcttttg
     2941 cagaacttga tccatgtggc gcttgtccat aaatttattt gccacatagc cattttcttg
     3001 gaactgagcc atcagcatct cacgaccctt gttgacagac aattccttat cttggttttt
     3061 aaagaactgg cgaatcttat tgcgcgcctt gctagtcttg accatattga gccagtcacg
     3121 gctaggtcca aaggagttcg ggttggcgat aatttcaacc tgatcccctg tctttaactt
     3181 ggttgtcagt ggaaccatgc ggccattgac cttggcacca gttgcttttt caccgacctt
     3241 ggtatggatt tcgtaggcaa aatcaatcgg tcctgaatct ttgggaaggg aacggacagc
     3301 tccatctggg gtaaaaacgt aaatctcctc agccaaatag ttttccttaa cagagtccac
     3361 aaattcctta gcatcatcag cctggtcttg gagctccatc atctccttga tccagttcat
     3421 tccaatagct gattccttgc tgttaacttg cccctttata cctttcttat aagcccagtg
     3481 agccgcaacc ccgtactcag ccacctcgtg catttccttg gttcgaatct ggaattcaat
     3541 cggccctttt ggtccataaa cagtcgtatg gatagactga taaccattgg ccttgcggtt
     3601 ggcgatatag tctttgaagc gacctggcat cggtttccaa aattcatgca cgtaaccaag
     3661 catggcataa acatcacttt gggtatctaa aatacaacga atagcaatca gatcatagat
     3721 ttcctcaaac cgttttctct tgtcctgcat tttgcggaaa attgagtaaa tatgcttggg
     3781 acgaccataa atcttccctt tcaagtgacg ttctgtcgta tactcctcta attttgtgac
     3841 tacctcatcc accaaggcct cacgctccct gcgcttttcc ttcatcatat gggtaatctt
     3901 gtaaaactcc gttggattga gataacggaa agacaagtct tctaattccc atttgacact
     3961 ggaaatcccc aaacgatggg caagcggggc atagatttcc atggtttctt tggaaatacg
     4021 ctcctgcttg tcttttcgaa gatgtttcag ggtccgcata ttgtgcaagc ggtcagacag
     4081 tttgaccaaa ataacgcgga tgtcctcaga catggccatg agcatcttgc gatgattttc
     4141 cgctaattgc tcctcgatcg atttgtactc gaccttgcca agcttggtaa ctccgtcaac
     4201 aatcacccgc acatcaggac caaactctct ttccaaatcg tccaaggtcg catctgtatc
     4261 ttccaccaca tcatgcaaga atccacaagc tactgttaca gcatccagct ttagcttagc
     4321 taaaatacct gccacttgga tagggtgaat gatataaggc tcgcctgatt tgcgatattg
     4381 accactgtgg cattcaacag catagaccaa ggccttatgg acaaaatgaa catcctcttc
     4441 cgttaaatat tctttggtta aagcgacaac ttcttcgcct gttaaattca cttctttcgg
     4501 catctctact ctccaattct tcctaccatt ttatcacttt tttaagaata tgaaaactag
     4561 attggaacag aataagaaaa aaataattca aaattgcttg ataattctga attattggcc
     4621 cataatatac tacgaagtta gattttaaac ttaggtgata gaaggagaga tagaagaacg
     4681 gaaaccatat tgtaacccaa agactttctg atttccccaa ttccattgaa gatacgaaag
     4741 ataaacggtg gaactcgtat cacatacact ggtaccttga ctggattttg gaattaatac
     4801 tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gttgctcaaa gcactgcttt
     4861 gaggttgtag ataagactga caaagtcagt cacatatata cggcaaggcg acgttgacgc
     4921 ggtttgaaga gattgttgac gcggtttgaa gagatttttg aagagtataa aaatcctcaa
     4981 gatactttct tctatccttt agtttataag gagaatacct atgaaaaaaa ctgctatttc
     5041 tatctttgct ctcctaatgt taggagtttg ctgcctgttc ctattcagcc agcaaagcta
     5101 taaaaaactc gttcaatact atgctaacga ccagaacctg cccagtagga taacttatag
     5161 tgaatatagc gacaaatgat aagccaacta cggtagcact ctaaacatca cgtctatcaa
     5221 acaagctaat gacggagttt atgcaaccta tgaagggcaa ttgacacctt tccaatattg
     5281 ataaattgat aaccagcctg tcttcatcta gtcatgctgg tttttaagtt cattttaaat
     5341 ccttacctat tctccctaac tgtgctatac ttaatttata ctcaatgaaa atcaaagagc
     5401 aaactagaaa gctagccgca ggctgttcaa agcactgctt tgaggttgca gataaagttg
     5461 acgcggtttg aagagatttt cgaagagtat tagtacattc tttgagattg gagctagtat
     5521 gaaaatccat aaaaccgtga atcctgttgc ctatgaaaat acctattatc tagaaggcga
     5581 aaagcacctc atcgtcgtcg atcctggtag tcattgggaa gccattcgtc agacaatcga
     5641 gaagatcaac aaaccgatct gtgctattct cttgacccac gcccattatg accatatcat
     5701 gagtctggac ttggttcgcg agacgtttgg caatcctcct gtctatatcg cagagagcga
     5761 agccagctgg ctctacactc ctgtcgataa tctctccggt ctccctcgcc acgatgatat
     5821 ggcagatgtg gtcacaaaac ctgcagaaca cacctttgtc tttcacgaag aataccaact
     5881 agaggaattt cgttttaagg ttctaccgac cccagggcac tctatcggtg gtgtttccct
     5941 agtctttcct gatgctcacc tagtcttgac gggagatgct ctattccgcg aaactatcgg
     6001 acggaccgac cttccgactg gtagcatgga gcaactcctt catagtatcc agacccaact
     6061 cttcacccta ccaaactacg atgtctatcc aggacatggt ccagctacta ctatcgctca
     6121 cgaaaaggcc ttcaatccct ttttctagca agatgatgac aatcgaaatt taagtaaact
     6181 atccagcaaa tctttctatt acaaaaggca tcctatcaag gttttcacac gtgattggat
     6241 gccttttttc tgatgactag attttttgta ttaccaaata atcacgcgct cctctggtga
     6301 acgccacatt ccgtctcctt ctttgacatc ataggttgta aagaaatcgt cgaagtttgg
     6361 tacttgcaca ttgacacgga gtttggctgg tgcgtgcaca tcgacgctag ccaaaagttt
     6421 cataaattct ggtcgacctt tcatgcgcca gatgcgaccg aagttgtaga agaactcttc
     6481 tgctgagaag tctgcttctc tcttagctgc ttcaagcgct gctgcgattc ctcccaagtc
     6541 agccacgttt tctgatacag tcaatttacc gttaatggtt gctccataag aatcctgtcc
     6601 atcaaattgg tcaatgactt tttgtgtttt ctccttgaag gcagcatagt cgctctctgt
     6661 ccaccaatcc ttgaggctac cattttcgtc aaaggaagcc ccgttagtat caaaggcgtg
     6721 ggaaatttca tgggcaatca ctgccccaat accaccgtag ttagcagaag atgactgatg
     6781 caagtcatag aaaggcgcct gtaaaatggc cgctggaaag acaatcaggt tcttctgagg
     6841 attgtagtag gcattgacca tatgagcagg catgccccat tccttatagt ctacaggctg
     6901 gttccactta ctccaactgt gcttgatttc cacacgcgca aaggctagag cattctcaaa
     6961 aagactggca gtttcattca ctaccttatc cttgtaacgt gcaggcaatt cttctggata
     7021 gccaatataa ggtttgatca cattgagctt cacgatagcc tgtttacagg tttctggagt
     7081 gagccagtca ttcttaagca gacgctcctt atagacatca atcatggttg ccactttttt
     7141 ctccacatcc gccttggctt ctggagagaa cttctcacgg gcgtaccaaa gacccagggc
     7201 ttgcttgaaa ggttcttgtg ctagatgata agctgctttg accttatctt ttgcctctgg
     7261 aactccagaa agggcacggc tgtaggcacc agacaaaaca cggatatcct ctgttaaata
     7321 gctggttgaa agattgacaa cactcaaaat caaggttgct ttaaggagag accaggcttc
     7381 ctcactgtag aattgctctg ctgcttgcca gaaacgttcc tcgtctacaa taaccttgtc
     7441 tggtaattgc ccaataactg ctttgaagaa gtcatccaaa ggtagggcag gcgcgaattt
     7501 cttaaaatct tcgtaagaat atggatgata gagtttagca tattctgaac tttcttcatt
     7561 agagagcacc actgccgcaa ctcggcggtc caattcaagt cttttttcta gcaagtcttc
     7621 aatttcttca tcagagaaat cataagcctt gaggagattt gcgctgcttt ctttccaaag
     7681 agtcaagagc tcttcgcgct gaggatgttc ttctgcatag taggtcgtat ctggcaagat
     7741 tgtgcttgga gcgctagccc atagaacatt gattctagca tccataaagt ctggcgatac
     7801 accaaaagga aggaagtttg gttttcctgc aagctcaaac tctgctagtt tagctgtaaa
     7861 atccgcaaaa gtttccaatt cttggaattc tttaaggagt ggtaagacag gtgtgatacc
     7921 gtcagcttct ctcttgtcaa aatcacgaac taggcggtgg tatttgacaa agttttccaa
     7981 gatagcatcc tcaggcactt cttcacctgc taaccacttg tctgttgtcg ccagcatcag
     8041 gtcttcaatt tcctggtcta aatcaacaaa acctccagtt tgagacttat ctgctgggat
     8101 ttcagctgtc tgttgccatt ctccattgat agcatcataa aaatcatctt gataacgtgt
     8161 catcttgttc tcgctttcat ttgtatttgc atttatctta acaaaaatca ctagggaatg
     8221 caattaataa ccatttaact attatttttt agctattata aaaaat
//
LOCUS       DAVKEV010000066         8059 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVKEV010000066 DAVKEV010000000
VERSION     DAVKEV010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8059
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.066"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            43..1470
                     /gene="galT"
                     /locus_tag="VWZ68_001921"
     CDS             43..1470
                     /gene="galT"
                     /locus_tag="VWZ68_001921"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU9372903.1"
                     /translation="MYNEIDKIYVKNRVLALIGEEGIDRISDENDLKQIKDYLVEIAL
                     KNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISPQEAVEEFYKLSKDSDY
                     IKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKLVKATNYPKCLLCMENE
                     GYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIFLNSQHVPMAITSKTFE
                     QLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPMEKAKFESEFCFKDFED
                     VNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEVDIIAMTEDVPHHTVTP
                     IARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKENIGLIEVMGLAILPPRL
                     KPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVNSVVQHEAGQVFARVLE
                     DAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            1483..2493
                     /gene="galE"
                     /locus_tag="VWZ68_001922"
     CDS             1483..2493
                     /gene="galE"
                     /locus_tag="VWZ68_001922"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU9372904.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSKLVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNIFE
                     SVNKIPIPYKIVPRRSGDVATYYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            2657..3316
                     /locus_tag="VWZ68_001923"
     CDS             2657..3316
                     /locus_tag="VWZ68_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEU9372905.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3341..4408
                     /locus_tag="VWZ68_001924"
     CDS             3341..4408
                     /locus_tag="VWZ68_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9372906.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            4512..5522
                     /locus_tag="VWZ68_001925"
     CDS             4512..5522
                     /locus_tag="VWZ68_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9372907.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5534..7225
                     /locus_tag="VWZ68_001926"
     CDS             5534..7225
                     /locus_tag="VWZ68_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9372908.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7228..7938
                     /locus_tag="VWZ68_001927"
     CDS             7228..7938
                     /locus_tag="VWZ68_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU9372909.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2710 a         1125 c         1593 g         2631 t
ORIGIN      
        1 acaattattg ataattttgt tgatagagta attgaatacg gaatgtataa tgaaattgac
       61 aaaatatatg tgaaaaatag agtactagcg ttaataggtg aggagggaat tgatcgcatt
      121 tccgatgaaa atgacctgaa acaaataaaa gattacttag tggaaatcgc cttaaaaaac
      181 ggtaaaatta aagatttaat cgaggaaaag gaatgtttag gagcagagtt aatgaatttc
      241 atagttcctt tacctagtcg attaaatgat attttttgga gttcatatga tatatcacct
      301 caagaagcag ttgaagagtt ttataagtta agtaaagata gtgattatat taaaacttct
      361 gctattgcta agaatattga gtttcgagca tcaactaaat acggagagct agagattacg
      421 ataaatttgt caaaacccga aaaagatcca aaaacaattg ctgctgaaaa attagtaaaa
      481 gcaactaatt atcccaaatg tttactatgt atggaaaatg aaggatatca ggggcgaata
      541 aattatccag cacgttcgaa tcatagaatt attcggttga aacttggtga cgaagtatgg
      601 ggattccagt attctcccta ctcatacttt aatgagcatg cgatattttt gaatagtcaa
      661 catgtaccaa tggctattac ctctaaaaca tttgaacaat tattggagat tgttgatatt
      721 ttgccaggat attttgctgg ttcaaattct gatcttccta tctcaggagg ctccattctt
      781 agtcataacc actaccaggg agggaaacat attttcccaa tggaaaaagc aaaatttgag
      841 agtgaatttt gttttaaaga ctttgaggat gttaatgctg gtattgtaaa atggccaatg
      901 tcagtaatta ggttacaaag tgaaaataaa aatcgcttgt tagatttagc tactaaaatt
      961 ctaaataagt ggagagaata ttcagattta gaagtagaca tcattgctat gactgaagat
     1021 gtcccacacc atacggtgac tcctattgct cgtaaagtgg acgggagata cgaattagat
     1081 attgttctaa gagataatca tactactgaa caatacccag atggtgtttt ccatcctcat
     1141 caagatgtac aacatattaa aaaggaaaat atcgggttaa tcgaagtgat gggacttgcg
     1201 atattaccac ctcgtttgaa accagagtta gaagaagttg gaaaatatct tttaggagag
     1261 gataatgcaa ttgcggatta tcatttagaa tgggccgacc aattgaaaga aaaatatcct
     1321 cgcattaata aagaagaggt taatagcgta gttcaacacg aagcaggaca agtgtttgcg
     1381 agagttctgg aagatgcagg agtttataag aatacaccgt ctgggcatga agcgtttatg
     1441 agatttgtta agtcggttgg aattaattag gaggaaaccc agatggcaat attggtaaca
     1501 ggcggagctg gttatattgg tagccatacc gtagtagaat tactaaattt aggaaaggaa
     1561 gttatcattg tcgacaacct ttcgaactct agcaaattgg tgctagaccg tattgaagca
     1621 attacaggaa tacgtcccgt gttttacgaa ttagatgttt gtgataaaca agcattgaga
     1681 aaggtatttg aacaagaatc gattgatgct gcaattcatt ttgcaggtta taaagctgtc
     1741 ggagaatccg tgcaaaagcc tgtgatgtac tacaaaaata atattatgag tacattggca
     1801 cttgttgaag tgatgtcaga atttaatgtt aaaaagattg tcttttcttc aagtgcgact
     1861 gtatatggaa ttaacaatca gtcacctcta attgagacga tgcaaacaag tgcgacaaat
     1921 ccttatgggt atacgaaagt gatgcttgag caaattttaa aagatgttca tgtggcagat
     1981 tcagaatgga gtattgcgtt gcttcgttat ttcaatccaa ttggtgctca tgagtctggt
     2041 ttgattgggg aagatccctc aggaattcct aacaacttga tgccttatat tgcacaagta
     2101 gcggtaggta agctatcaga gctaagtgtg ttcggaaatg attatgatac gcttgatggt
     2161 actggtgtgc gtgattatat ccatgtagta gatttagcaa taggacatat aaaagcttta
     2221 gaaaaagtat ctgaaaaaac agatgtttat atctataacc taggctcggg agaaggcact
     2281 agtgtattac aacttgtaaa tatatttgaa agtgttaata agatccctat tccttataaa
     2341 atagttccaa gacgttcagg agacgttgca acttattatg caaatgcaga caaagcatat
     2401 aaggaattaa attggaggac aacaaaatcg attgaagaca tgtgtagaga tacatggaat
     2461 tggcaatcaa aaaatcccaa tggctataat tgatgatact gtctatatga gtgctgtatt
     2521 ttggaaaaat tacttaacct tttaatgaaa gataaattaa aaaaaatgtt tgacagcgct
     2581 tgacaaagga aacggtttca ttgtataatg taaacacaat gacaccgatg tcaaatataa
     2641 aaaagaaggt ctttatatga aaaacttaac aaaaattaag ttcaaagaaa atggggaatt
     2701 taatcatttc cctgggaata cagttgtagc aaatctttat actaaacaag atttgatgga
     2761 agttgttgat attattcaat cacgttatag agaattacca tttatcgata agtttacttt
     2821 aactccaagg aattctattc acatgactgt aattgaattg ttgtgccatg aaaatcgtga
     2881 aacggagttt tggagcagta atcttcctct agatacacct ttacaggaaa tacatgatta
     2941 ctttgctaaa caacttgaaa tttttccatt gttggatgaa gaaattcata tgcgtataac
     3001 tgaaatggga aaacaaaaca tactagttga acctgcagat gaagcttctg caaagagatt
     3061 agaagaaatt cgtacttatg tctcagaaaa agcaggtgtt tgtttcccta atcatgatag
     3121 atatcaattc catatttcaa ttgggtatct tcggattcct ctaaccgaag aggaggaaga
     3181 agagtttact aaagtcagag cagaattaac tgaaatttta ttagagaaga ttccaactat
     3241 tactgtaaac cgtattgact atactgtatt tgaagatatg agacaatttg ttccatatca
     3301 cgaaaaattt aaataaaata ataaaaaagg agaacttatc atgaaaaaaa tgaaagtttg
     3361 gtctactgta cttgcaacgg gagttgctct tactacactt gctgcttgct ctggaggttc
     3421 aaattctacg actgcttctt catctgaaga aaaagctgat aaaagtcaag aattagttat
     3481 ctattcgaac tcagtctcaa atggtcgtgg tgattggtta actgctaaag caaaagaagc
     3541 tggttttaat ataaaaatgg ttgatatcgc tggcgctcaa ttagcagacc gtgttattgc
     3601 tgagaagaat aatgcagttg cagatatggt atttggaatt ggtgctgttg actcaaataa
     3661 aattagagat caaaaattac tagtacagta caagcctaaa tggttagata aaattgatca
     3721 atctttatca gataaagata attattataa tcctgtgatt gttcaaccat tagttttaat
     3781 tggggcgcct gatgtaaaag aaatgcctaa agattggact gaattaggta gtaagtataa
     3841 aggtaaatat tcaatttatg gtcttcaagg tggtacagga cgggcaattc tagcaagtat
     3901 cttagttcgt tacctggatg aaaaaggaga tttaggcgta tcagaaaaag gatgggaagt
     3961 tgcaaaagaa tactttgcaa atgcctatac tcttcaaaaa ggtgaaagct cagttgttaa
     4021 agcgttagat aaagaaagcc caattcaata cggtatgatc tggggttctg gagcgttaat
     4081 cggacaaaaa gaacaaaatg ttgaattcaa agttatgact cctgagattg gtgtaccatt
     4141 tgtaactgaa caaactatgg ttttaagcac tagtaaaaaa caagcgttag ctaaagaatt
     4201 tattgattgg tttggtcaat cagaaattca agtagaatat agtaaaaaat ttggatctat
     4261 tcctgcaaat aaagatgccc taaaagagtt acctgaagat acgaaaaaat ttgttgatca
     4321 agtgaaacca caaaatattg actgggaagc tgttggaaag catttggatg aatgggtaga
     4381 aaaagctgaa ttagaatacg taaaataaga aataagagtt attttttatg tccaagtctc
     4441 tctattattt ctaaatttaa ggaagaaata aagagaggct tttggtttta gtaatagagg
     4501 gagttagtga gatgattaaa tttgataata ttcaaattaa atatggtgat tttgttgcaa
     4561 ttgataatct gaatttagat atacatgaag gggaattctt tacatttctt gggccttcag
     4621 gatgtggtaa atcaactact ttgagagcat tggtaggttt tttagatcca tcatcaggaa
     4681 gtattgaagt taatggaaca gatgtcactc atttggaacc tgaaaagcgt gggattggta
     4741 ttgtatttca atcttatgcg ctatttccaa ctatgactgt ttttgataat attgcatttg
     4801 gtttaaaagt taagaaggta gctccagatg ttattaaagc taaagtatca gcagtggcag
     4861 caaaaattaa gatctctgat caacagttac agcgtaatgt atcagaatta tctgggggtc
     4921 aacaacaaag ggtagcattg gctcgtgctc tggttcttga acctaaaatt ctttgtctag
     4981 atgaaccatt gtcaaacctt gacgcaaaat tacgtgtaga tttgagaaaa gagttgaaaa
     5041 gacttcaaaa agagttaggt attactactt tatatgttac tcatgatcaa gaggaagcct
     5101 tgactttatc tgatagaatt gcagtcttta acaatggata catcgaacag gtcggtacac
     5161 cagtagagat ttatcataat tctcaaactg aatttgtatg tgattttatt ggagatatta
     5221 atgttttgac cgatgaaaca gtccacgaag tattattgaa aaatacaagc gttttcttag
     5281 aggataaaaa aggatacatt cgattagaga aagttcgatt caatcgtgaa actgaacaag
     5341 attttattct aaaagggaca attattgatg ttgagttttc tggagttaca attcactata
     5401 caataaaagt ttctgaaagt cagattctta atgtaacaag tattgatagt caggctgcta
     5461 ttagatctgt cggagaaagt gtggaattat ttatcacacc atcagacgtt ctgcaatttt
     5521 aaggaggtgc agtatgcgtc ataaattaaa tttaaaagat tggcttattc gtttagggtt
     5581 aatctggttc ttagtaacat ttattattta tccaaacttt gatctagtag tgaatgtatt
     5641 tgtaaaagga ggagaatttt cccttgatgc tgtacatcgt gttctaaaat ctcagagggc
     5701 acttcagagt attatgaaca gttttaagtt agcattttca ctcattatta cagttaatgt
     5761 cgtaggtatt ctttgtgttc tatttacaga gtactttgat attaaaggtg ctaaaatttt
     5821 aaaattaggt tatatgacct ctttaattta tggaggagtg gttttagcga ctggatataa
     5881 atttgtctat ggtccttatg gattgattac aaaattttta caaaatgtta tcccttcttt
     5941 agactctaac tggtttattg ggtatggtgc agtcttattc attatgacat tttcaggaac
     6001 tgctaatcat acattgtttt taacaaatac aattcgaagc gttgactatc acactattga
     6061 ggctgctcga aatatgggag caaaaccatt tactgttttc cgaaaagtag tgttaccaac
     6121 cttaattcca actctatttg cacttactat tatggttttt cttagtggtt tatctgcagt
     6181 agcagcaccc atgattgttg gtggtaaaga atttcaaact ataaatccaa tgattattac
     6241 atttgcaggg atggggaatt ctcgtgattt agctgcctta cttgcaatta ttttaggtat
     6301 tgcaactaca attttgctta ctatcatgaa taagatagaa aaaggtggaa attatatttc
     6361 tatctctaag actaaagcgc ctcttaaaaa acaaaaaatt gcgtctaagc cttggaatat
     6421 cattgctcac attgtagcat atggattgtt cacagttttc atgcttccac taatttttat
     6481 agtattatac tcatttacag atccagttgc aattcaaaca ggtaacttaa cattatcaaa
     6541 ctttacttta gaaaattatc gcttattctt tagtaatagt gcggcattct ctccattctt
     6601 ggtcagcttt atttattcta ttattgctgc gacaacagca acaattctcg cagttgtatt
     6661 tgctcgtgtt gtcagaaaac ataaatctcg ttttgatttc ttatttgaat atggtgctct
     6721 acttccttgg ttactaccaa gtacactttt agcagtaagt ttattattta cttttaatca
     6781 gccacaattt cttgttttga atcagatttt ggtaggtagt ttggtaattc tacttattgc
     6841 atatatagtt gtaaaaatcc cattttctta tagaatggta cgtgctattt tatttagtgt
     6901 tgatgatgag atggaagatg cagcaagaag tatgggtgct tcaccttttt atactatgat
     6961 gaaggttatc attccattta ttttaccggt tgttctctct gttattgctt taaactttaa
     7021 ctctttatta actgacttcg acttatctgt attcctttac catcccctag ctcaaccatt
     7081 aggtattacg attcgatctg caggtgatga aacagcaaca tctaatgcac aagctctggt
     7141 atttgtttat acaattgttc tgatgattat ttctggaacg gtattatact tcacacaaag
     7201 accggggcgt aaagtaagga aataatcatg acagccacta gtcttgggtt atcaaatatt
     7261 gaaatagttg tcaggattgt tttatcagta gtcattggta gtataattgg tttagagaga
     7321 gggagcaaat cccagcctgc aggcatccga acttatagta ttgtttgtct agctgcatgt
     7381 ttgattatga tgacgaatga atacgtatct tataaatttg ggacaggaga tcctacacga
     7441 ttaggagctc aagttatatc aggtgtgggt tttctaggcg ctggaacgat tcttattaca
     7501 gataagaaga aaattacagg tctgacaact gcagcaggca tttgggcttc ggcaggaatt
     7561 ggattagcta ttggagtagg tttttatgag ggagctcttt tagtagccat ttctgtttgg
     7621 ggtgtgatat ccatgttcca accactaaaa aaatatctgc aaaatcgttc taaaatgatt
     7681 gaattgtata tagtagttaa atctacagaa gcctataatc gtgtattggt ttattgtgca
     7741 gaaaatggta tcagaatgac cgattcaaga acagcgtttg gagatgttaa ttctgacaga
     7801 attgaatact ttgatgttcc ggacaaaaaa atagcgtcat ttattactct ggaattatca
     7861 ggtagatttg aacatcttcg actgatggaa gaaattgcta atattgtagg tgttatttat
     7921 gtcgaagaaa ttagctgaaa tttagtaaac aaagggacag atgtttttgt ccttttgttt
     7981 tttagatgtt ttaatcatct aatttttgag tagatttttg ctcagaggtt tttatgaaag
     8041 attataaaat caattttga
//
LOCUS       DAVKEV010000067         7773 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVKEV010000067 DAVKEV010000000
VERSION     DAVKEV010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7773
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.067"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(173..1588)
                     /locus_tag="VWZ68_001928"
     CDS             complement(173..1588)
                     /locus_tag="VWZ68_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU9372910.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAKLLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1601..3439)
                     /locus_tag="VWZ68_001929"
     CDS             complement(1601..3439)
                     /locus_tag="VWZ68_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU9372911.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVIPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     DVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDESVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3457..4299)
                     /locus_tag="VWZ68_001930"
     CDS             complement(3457..4299)
                     /locus_tag="VWZ68_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU9372912.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLT
                     KNLD"
     gene            complement(4599..7277)
                     /locus_tag="VWZ68_001931"
     CDS             complement(4599..7277)
                     /locus_tag="VWZ68_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU9372913.1"
                     /translation="MAVFVSLDGIVVEVLDVFSSFDGDSEFFLCKRLKDKSQFVMERS
                     RFEEMFQLQSSHLTTQEKLQLFTSVFAGRYDVYAKNFINEQGKIQYFPSYDYGWKQLP
                     PEKRSFQTLTNSVLKSHFRGETAIGIFPMHLDDSCHFLVLDFDEGDWKEAGLTIRRIA
                     RERQMEAHLEISRSGHGLHIWFFFEEAIPSREARLFGKKLIELAMQESMQLSFDSFDR
                     MFPNQDVLPKGGFGNLIALPFQGEAYHQGRTVFVDEQFQPYEDQWRYLQEIQRVSTAK
                     VALLIQEELGKQELDKGLKIVLSNMIQLEKSSVTPKTLFFLKNMASFSNPEFYLKQAM
                     RQPTYQIPERMYLFGESDHYLWLPRGLLYPLQDKFKQVVVEDRRKVQRSISVEFKGEL
                     TFEQELALSDMTSKENGLLHAETGFGKTVLGAALISERKTKTIILVHNKQLLDQWLDR
                     LNCFLTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKLVDVVMIQSLFKLENSQSL
                     LDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPERKNGHEPIVFQRIGEILH
                     TADKRETDFKRQLQLRFTSFGHLEIEKTKASNFIQLSDWIATDSARNQLILKDILAQV
                     AEGRNILVLVNRIQQIDVFEKLLKEKEVDDCYIISGKTKVRERTSLLETLEQLDKGFV
                     LLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIHRNYKDKSLVRIFDYVDIH
                     VPYLEKMFQKRQVAYRKMDYRAIEGEEKQFVYVDSRYEKVLIEDLAGERQECLLILPY
                     VHQTKLMNFLKEFRISQIEICIPETVANKAWLDQLKSQKIKVSFTQSKIVTPILLVNK
                     TIVWYDAMPLLGKVDEMTILRLESASIVSELVAGLR"
     gene            7526..7735
                     /locus_tag="VWZ68_001932"
                     /pseudo
     CDS             7526..7735
                     /locus_tag="VWZ68_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2566 a         1606 c         1083 g         2518 t
ORIGIN      
        1 ccaatctatc ctaagttaac tatttataat cggctctctg taacaaaatt aaattaatta
       61 atccccctat aaaataaaga ggtttagaat ttgatgtctt ccaaacctct ttatttcata
      121 ttcaatgaga tgttgcctta accgtgataa tatctaatca tcaataaaca aactatttga
      181 ataaggattc tccatttgat tcaatcactc ctttatacca agtaaaggac attttcttat
      241 atcgattgaa tgtgccattt ccatcatcat ttcgatcaac ataaatgaga ccgtacctct
      301 tagaaagctg tgcagtggac atagaaacgc agtcaataca tccccaagac gtatagccca
      361 taatttccac accatcttgt agagcttcag ctacttgcaa taaatgttct ttcatatact
      421 gaattctata atcatcttgg actgttaagt tattaaattc atcttttatt agttgatctt
      481 tagcacctaa tccgttttcc actataaata atggaatttg ataacggtca taatatctat
      541 ttaaaattat acgtagtcca attggatcaa tttgccatcc ccactcagaa gactctaaat
      601 aaggatttac taagccacca ataatattcc cttctcctga attatactgt gttggaagag
      661 cagattgagt cacactcatg taatagctaa aggataaaaa atctacggta taatttttta
      721 ataactttgc atcttcagct gcaaactcta tgttaatgtc attttcctta aaatatcttt
      781 ttgcataatt cggataataa cctctaacat gcacatctga aaatagataa tttagattct
      841 catactcatg agtcgcccat acatcttttg gatttggagt cattggataa gctggcatag
      901 ctaataccat acaccccacc ttaaactctg aattaatctc acgagcaatt tttgtaacca
      961 aactcgaggc gactaattca tgatgtatag cttgatataa ttcttgtttc gaaagattct
     1021 ccttaggtat atctattcct ccactagtaa acggtaattc caaaacagag tttacttcgt
     1081 taaatgtaag ccaatattta actttatctt tatacctttc taaaactgtt cgagcaaatt
     1141 tttcataaaa atgaatcatt ctcctatcaa tccatccatg atattttctt gctaaatata
     1201 atggagtctc atagtgtgaa agagttacaa gtggttctat cccgtgagca tgtagttcat
     1261 caaacaattc atcataatat ttcaacccag cttcgttagg ttcttcctca tctccttttg
     1321 gaaaaattct actccatgca atagaagtac gaaaaacatt aaagcccatt tcagaaaaca
     1381 aggatatatc ttccttatat ttatgataaa aatcaatacc tatcaatttt aagttatctt
     1441 ctgtaggatt ttctgttgct tctcctaatc cacctttggg taacacatcc tgaactgata
     1501 agcccttacc atcttcatta tatgctccct ctacttgatt agctgcaaca gctccacccc
     1561 aaagaaaatc atctggaaaa atggtcataa ctttcctcca ttataatatt accagtaatt
     1621 ccttagaatg ctcgattgtc tgattattag gtaatactaa tacatctaga aaatcattgg
     1681 tattcgttac aattactggt gtaactgttt cgtagccttt agtcttgatt aaattcaagt
     1741 ccatttcaaa aatcaactga tttttgaaaa ctctgtctcc ttcttctaca tgactaataa
     1801 aaccttgacc ttttagctca acagtatcta atccaatatg aattagtaac tcaacactct
     1861 catcactctt caatccaatt gcgtgcttag tcggaaaaat atttgtaatt ttcccatcaa
     1921 atggtgcata aaccttacct tcacttggaa taatcgctac tccgtctcca attagtttat
     1981 ctgaaaatgt tttatcctgg acatcgctta acggaatgat ttctcctgat ataggagaaa
     2041 atatcatttt tttatttgaa actccagctt taacttctaa attgctagaa ctctcttctt
     2101 catcgattcc aaatatataa gctaatacaa aggtaataac aaccgaaata accgccacaa
     2161 ttaaagcatt tacaatattt gatggtacat cagaataaat aaattgaggc aacgctatca
     2221 aagatgggac agcaaataga tacgctttaa cactagtaag acctgcaaat aatcccgcta
     2281 atccaccacc aatcatagct gcataaagcg gttttttata ttttaaagtc acaccatata
     2341 atgcaggttc ggtaatccct gcaagtaagg ctgagaaacc tgctgcaaaa gcaatttgtt
     2401 ttgtattatt atttttactc tttaatgcaa cagccatcga agcagcccct tgagctaagt
     2461 ttgaccctaa cattgctgga agaattaata cgtctggagt agcaatagat gccgccaaaa
     2521 aaataggtgc aaaagcccaa tgcattccag tcataacaat aaatggcata atagcaccaa
     2581 gaatagctaa tgtaagccat ccagctacat catacatttg cccaactaga tttgataatc
     2641 cttcaccaac aattactcca ataggcccga ctacaactaa ggcaatacag cttgatacta
     2701 ataatactag cgtaggttgc aaaaaactct tagtaacagc tggtgttaat ttagcaatca
     2761 ttttttcaat atatttcatc aaccaaacca taataagaat tggaacgact gacgaaccat
     2821 aactagctgg tatcacaggt acaccaaata aactaagagg attccctgat tgcaccattt
     2881 gaacaaaatt tggatggaga agtacacctg ctacagacat agctaatgta gatgttactt
     2941 ttaatttttg tgatgcagaa taagctaata acagcggtaa gaaataatat ggagcatccc
     3001 caaaaaatgt caaaaaagca atagtctgag aatctgattg caatatacca agcattggta
     3061 aaataattac caagactttc agcatacctc cccctaacat tgctggaatg attggagtca
     3121 tggaaccagc gatatactca atgattcttt ctaaaatatt ccctttgtgc ccttgaacaa
     3181 ctgaatcgga ttcaaaattg ccaagtttaa cgaattcttt ataataatta gctacatcat
     3241 taccaagtat aatttgatat tgtccattct ttttcataat acctattaca cctggtatct
     3301 tcttcacatc atcatcattg actaaatttt catcttttaa ttctaatctt aaacgtgtta
     3361 cacaatgggt aactctattg acattttttt cacctccaat tacatcgagg attttttgta
     3421 ccttatcttt ataactcatg gtattctcct attctattaa tctaaatttt ttgttaagcg
     3481 acgaatatga gccatcaaat aaactaattc actagaagtc agcaaataat tgtactcagt
     3541 ttgtataaac attgccacct gttcaccaca ttcatattct ctaggatatt tatttttcat
     3601 taatgctaac aagtcttcat catcatcatc gtcacaataa gttgtatttt caaccaagcg
     3661 atgggcaaat aattttatat gagttatgaa tctataataa tcaatagaat cttggttaaa
     3721 ctcagtacaa tagaaatctt gaatgatttt ctcaattccc ataattattt cagtgatttt
     3781 atacgactct tgaaaattat tttctaaatt agcattaaca aaatgtagcg ctatgaatgc
     3841 agcttcgtca attggaagtt caatacctaa ctcttttttt attatttgta aagccctttt
     3901 cccaagctca aattcttctt tataatattt cgagatttcc cagcgtaggg gattcgaaat
     3961 aataactcct tctttataac gttctatact cgaagaaata tgatccgtta gatttatata
     4021 gataatctca tcaaaattat tacctaatgt tattttacct agattaatta ttttttcggt
     4081 gatgtacacc aactccaaag gaacgttaat aaacatctct gtaaaacggg tcatattatc
     4141 tctatttttg agaaaaaaac ttttctcaat atcaattgga tttactttat ctccaatttt
     4201 tcttccaaaa gctattcccc ttccaaaaag aagaatatcg atatcttttt tactttgcgc
     4261 aattacggca ttgtggttta gtattcgttt tatgatcata aaatttccct tttaaaataa
     4321 aaggaaccta cttaaaaaca tcaagaaact tcttctgatg tgattaaata ggttcctgct
     4381 cacttgtatt agtgataaca tccttttatt tcaattttta atggtgacat gaagcttaaa
     4441 taattaataa ctctgtaacc attttcattt taagatattt caatctattt gtcaagtact
     4501 tgtagaaatt tttttatttt gtgtgattcg aatgtgataa tggcaacagt ctcactaaag
     4561 aaatgaaaat catacataga aatttttaaa aattttctct atcgtaaacc tgccactagt
     4621 tcagaaacta tactagctga ttccaaacgt aatatggtca tctcatctac cttccctaat
     4681 aatggcattg catcatacca aacaatagtc ttattcacca aaagaatagg cgttactatt
     4741 tttgattgag taaaagacac tttaattttc tggctcttca actggtctag ccatgcttta
     4801 tttgcaaccg tctctggtat acatatctca atttgactaa tcctaaattc ttttagaaaa
     4861 ttcatcagtt ttgtctggtg cacataaggt aaaataagca gacattcctg tctttcccct
     4921 gctaagtcct ctatcaacac cttctcatat ctactatcaa cataaacgaa ttgtttctcc
     4981 tcaccctcaa tggcacgata atccatcttt cgataagcta cttgtcgttt ctgaaacatc
     5041 ttttctaaat aaggaacatg aatatccaca taatcgaaaa tacgcaccaa agacttatcc
     5101 ttgtagtttc tatgaatccg acctgcatac tgaattaaat tatttttcca agaaaagggt
     5161 gctgccaaga taagcgtgtc caactgaggt aagtcaaaac cttcgccaat gtattttcca
     5221 gtagacaaca aaacaaaccc tttatctaac tgttctaacg tctccagtaa actcgttctt
     5281 tctcggactt tggtttttcc gctaataatg taacagtcat caacctcttt ctctttcaat
     5341 aacttttcaa agacatctat ctgttgaatt cgattaacta aaaccaagat attccgtcct
     5401 tctgccactt gggctagaat atccttgaga atcaactgat tcctcgctga gtctgtagca
     5461 atccaatcac tgagctgtat aaaattactt gctttggtct tttcaatctc caaatgacca
     5521 aaagaagtga atcttaattg caattgccgt ttaaaatccg tttccctctt atcagcagta
     5581 tggagtatct caccaattct ctgaaaaaca ataggctcat gaccattctt acgctcaggc
     5641 gtagccgtca aaccgtaaag atacttccct ctaaactgag caacaacttt ttcaaacatc
     5701 aaggcagaga catgatgaca ctcatccaca atcatcatct catactcatc caaaagactt
     5761 tgactatttt ccaacttaaa tagagattga atcataacga catcaaccag tttactcagc
     5821 catttcttag tcccaccgta ctgtccaaca tagccgatta ccttttcacg acctgatgcc
     5881 gtataacgga tagcctcctc ctcttcgaaa gtcaaaaagc agtttaagcg atctagccat
     5941 tggtctaaga gttgcttatt atggactaga ataattgttt ttgttttccg ttcagagata
     6001 agagcagcac ctaaaacggt cttcccaaaa ccagtctccg catgaagtaa accattttct
     6061 ttagaagtca tatctgacag ggctaactct tgctcaaaag tgagttctcc cttaaattcc
     6121 acgctaatag acctttgtac ctttctccta tcttccacaa ctacctgctt aaatttatct
     6181 tgcaatggat acagcaaacc tcttggcaac cataaataat gatcggattc tccaaataaa
     6241 tacattctct caggaatttg ataggttggc tgtcgcatag cctgctttaa ataaaattcg
     6301 ggattagaaa atgaagccat atttttcaag aaaaacagtg tcttgggtgt cacagacgat
     6361 ttttcaagtt ggatcatatt ggataagacg atcttcaacc ccttgtccaa ttcttgcttg
     6421 cctaactctt cttggattaa cagtgccact ttagcagttg aaaccctctg aatttcttgt
     6481 agatacctcc attggtcttc ataaggctga aactgttcat ccacaaagac cgttcgccct
     6541 tgatggtaag cttctccttg aaaaggcaag gcaatcaaat ttccaaatcc ccccttagga
     6601 aggacatcct gatttggaaa catgcgatca aaagaatcaa aggacagttg catactttcc
     6661 tgcattgcca gttctatcag tttctttcca aacaagcgag cctctcgact cggaatcgct
     6721 tcctcaaaga agaaccaaat atggagtccg tgacccgaac gagaaatctc taaatgggct
     6781 tccatctggc gttccctggc tattcttcga atggttaaac cagcttcttt ccaatctcct
     6841 tcatcaaaat ccagtaccaa aaaatgacag ctatcatcta agtgcatagg aaagataccg
     6901 atagctgtct ccccacgaaa atgagatttc aaaacggagt tcgtcaatgt ctggaaactc
     6961 cgtttttcag gtggcaactg cttccaacca taatcatagg aaggaaaata ctgaattttc
     7021 ccttgttcat tgataaaatt cttagcataa acatcataac gtccagcaaa cacggaggta
     7081 aacaattgta atttttcttg cgtcgtcaag tgactacttt gaagttggaa catctcctcg
     7141 aaccgagagc gttccataac aaactgactc ttgtctttaa gacgtttaca caagaaaaac
     7201 tcactatccc catcaaaaga agaaaagaca tcaagcactt ctaccacaat tccatccaaa
     7261 gacacaaaaa cagccataag agtcacctcc ttgattccta taggctgatt ataacaagaa
     7321 tagctgaaat tgtacacgaa aataaaatcc gaatagcact cattttgtat gcgactaata
     7381 gtccatctcg ctccggaatg tacgaggtaa atagagttta aacgagcagt ctataaaatt
     7441 caaaaaacgc atattaccaa ggttgttttg aactacaccc caaaagttag acagaaaaaa
     7501 tctaactttt tggggtgttt ttattatgaa attaacttat gatgataaag ttcagatcta
     7561 tgaacttaga aaacaaggat atatcttaga gaagctttca aataaatttg ggataaataa
     7621 ttctaatctt aggtacatga ttaaattgat tgatcgttac ggaatagagt tcgtcaaaaa
     7681 aggaaaaaat cgttactatt ctcctgattt aaaacaagaa atgattcata aagtctgaca
     7741 tgaaggctgg actaaagata gagtttctct tga
//
LOCUS       DAVKEV010000068         7645 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVKEV010000068 DAVKEV010000000
VERSION     DAVKEV010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7645
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.068"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(1..846)
                     /locus_tag="VWZ68_001933"
     CDS             complement(1..846)
                     /locus_tag="VWZ68_001933"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEU9372914.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKACAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            1102..2129
                     /locus_tag="VWZ68_001934"
                     /pseudo
     CDS             1102..2129
                     /locus_tag="VWZ68_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(2430..4319)
                     /locus_tag="VWZ68_001935"
     CDS             complement(2430..4319)
                     /locus_tag="VWZ68_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEU9372915.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGTEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKEQSKQLLTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFERDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLLGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            4457..6022
                     /locus_tag="VWZ68_001936"
     CDS             4457..6022
                     /locus_tag="VWZ68_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU9372916.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYANAKSLDDFNGAKITSQQGVYLYD
                     LIAQITGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMVQVEPGF
                     KTGEEDTAIAIGLRKDDTRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTITGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWILNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            6022..6762
                     /locus_tag="VWZ68_001937"
     CDS             6022..6762
                     /locus_tag="VWZ68_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9372917.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(6871..7086)
                     /locus_tag="VWZ68_001938"
     CDS             complement(6871..7086)
                     /locus_tag="VWZ68_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372918.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
BASE COUNT         2417 a         1703 c         1355 g         2170 t
ORIGIN      
        1 ttatacaaat aaacggacaa aactgtaaag tagcaaaaca ctaccaagca cgatacggta
       61 tttaccaaaa agggtgaagt cgtgtttttt cacatagctg gtcaagaagc gaatagccac
      121 catgctgacc gcaaaagcta ctcccatcgc gaccaagagc aaaaacaatt gcccaaagct
      181 caagagttct ccggctttca caaatttgaa aatctttaag gcactagctc caaacataac
      241 gggaatccca agatagaagg taaattctgt cacaactgaa cgactggttc catttaacaa
      301 accaccgaca atcgttgcac ctgaacggct agtccctggt aaaagagcaa gaacttggaa
      361 gagtccgata tagaaagcgg tcgtataagg aagcttgtcc aactctgtta cacttggctc
      421 gatagcacac gctttattgc gcttttccaa atagatgaag gcaaccccgt agataatcaa
      481 catgagagca actgaaacca tgttatggaa gtgggtatca aaccaatcat caaatttaaa
      541 gacaccaagt aaaggtaaag tagcaatcaa gaccttcaac catagtctcc aagtcttacg
      601 aacttcctgt ttgtccttag tcggtttaaa aggattgagc ttgttaaaat aaatcaccat
      661 aactgctaaa atagcaccaa gctgaatcac gacattaaac atggacataa aggcttcatt
      721 ttgattttgg tattggataa actcctctgc taaaatcaag tgacctgtac tggaaatcgg
      781 caaccattcc gtaattcctt caacaatccc gaagaagata gattttaaaa tttcaataag
      841 atacatatat ttctccttat attatattta acgcagttag ctactgccaa agcccaagtg
      901 gtatacttgg aataagccac tgtggattag ttcatttcct ccaatcgctt gacgatttcc
      961 gaaaggatct aaccacagct ttttgtttca attggtaatg agtttgataa cgcatagacg
     1021 ttttatctcg tctaaggtaa caaggcaaaa agttcgtgga taaccaagta gacttgaaat
     1081 actatatctg gaggtactcc catgctttat gtgggcattg atgtcgctaa aaataaacac
     1141 gatgttacag ccttgaatgt tcgaggaaaa ctgttcttaa accactcact ttttcaaata
     1201 ataaagctgg ttttgaacta ttagatctgt ctcttcgaca gctcaaccaa gactgtctca
     1261 tcgctcttga agataccgga cattatgcct ttaatctact gaacttcctg catgaacaag
     1321 gatataaagt ttacacctac actcctttgc tcatcaagga atttgccaaa tcattatcac
     1381 ttcgcaagac taaaacggat aagaaagacg ctcatggcat cgctcttaaa cttctttctg
     1441 accccaatcg tgaacaattt caacacgata atcggcaagt agaactaaaa atactggcta
     1501 gacatattca tcgtctcaag aaaaaacagt ctgattggaa agtacaatac actcgttgtc
     1561 ttgatatcat ctttcctgag ttggataaaa tcgttggaaa gcattcagaa tatacctacc
     1621 aactcttgac atgctaccct aatcctcaga aaaggcttga ggcaggattt gataagctga
     1681 tagaaattaa gcgattgacc gcttctaaaa ttcaggatat cctctcagtc gcacctcgtt
     1741 ctatcggaac aacatctcct gctcgtgaat tcgaaatcat cgaaaacatc aaacattaca
     1801 agaggctcat tgacaaggcg gaaaaatgtg tcaatgactt gatggctgag ttcaactcgg
     1861 tcatcacgac ggttactggg attgggaatc gtttaggggc ggtcatttta gccgagattc
     1921 aaaatattca tgcctttgat aatcctgctc aattacaagc tttcgctgga ctggattctt
     1981 ctatttatca gtcaggtcag attgatttag ctggaagaat ggtcaaacgg ggttctcctc
     2041 atctgcggtg ggcactcata caagctgcca aagcatgcgc tcgcttttca cctgctttta
     2101 aggcctatct taagactaag ttagaataag aaaaacatta caatgtagcc atcatccacc
     2161 ttgcaaaaaa acttatccga accctgtttt atatcctaaa aaagagctgc catttgacga
     2221 acaaaaagtg atgtaatttc tgaaatcaac acaggattac ctttgaaaaa atggactttt
     2281 tcaagggctt tttgccgtgc tctaaaatca tcgccaaatc atcaaattga aataagaaat
     2341 agtttagata aaattattga cttttcttat agtttgtctt tcttctatct tccattatat
     2401 catacttttt cagtctatgg tagctctctt taaaaggctc cgatactgcc gccacctccg
     2461 cctccagaga agccaccgcc agaacttcca cttccagaag atacggagta ggtacttgct
     2521 gtatttgcga cactagcata atggctcatt tgcgcgcttg aatgataaaa catactgtgc
     2581 cagccataag ctacatagag attgatatct ggattttcaa cttgaatctg atgaaccttc
     2641 atcaaatgac taaccttgtc cgcatagcca agtaaggttg catagaccaa gagacgattc
     2701 caaacaacaa tactttccaa ttcagcctta tccagtcgtg caatctcacg taacatattt
     2761 tcaaaactgg tccagagata gtagacctca gctcccgctt catttagaac accatcacga
     2821 ttatctagtc gaagcttcca ataatagaaa acagacaaaa ctaaccctag aaaaccaagt
     2881 attggcaaag ggaggtaaag atagccatga acgtctaaac tgtacaagaa caaaccaaat
     2941 ccgataaata ggggcaggat agtcaaggca cccataccca cttgcaaggc cttttcccca
     3001 ccagttaaag gacgataata atctgggagc ccccagaagg aaactcgttt tctcactcct
     3061 tcttgcatct ggttcaatac ctcttcaaaa gaagatttga gttgaagccc tcttgcttga
     3121 atccgttttt catcagaaac tttggctcta cgataaagac tatcagatac cttgtaatcc
     3181 gcaaacaaat tggaaagagt ttcttctttt ttacctgaaa aggctagatt tagacagtct
     3241 ctctcaaagc ttgacaaacc atcttctttt actagcctca aaccaactgc atctccttct
     3301 gaaatgatag agacattccc acggtctatc acatctagca aggtagcttg aataagttga
     3361 tcaaaggtga attttccagc tcccttgacc aagggactca cttcctccaa ggaggtcgag
     3421 tagactgctt ctgataaaac cataggctct aattccattg gtggttcata gagacgatga
     3481 tttttggcat atttgactga aggagtggtc tttcttctat aaataaaata gaagcagaca
     3541 ctcaataaca aggagatgga aaggatcgaa gggaggaccc aagtaagtag ttgtttactt
     3601 tgctcttttt ctctaacaat cgagtcttct atcttattaa actcttctaa tcgattccct
     3661 ttcaatccct gatccctagc gctagcaaaa tcggtccgag gccaataggc atgcaactca
     3721 actccacgct tagccggaag attgtctaaa cggatagtat aatcaaggtt actcttttca
     3781 atcgttccct ctctaaaaag tttccctgta tggaaaaaga gtttttcagt ccccttgtct
     3841 ccccttacat gaaattcaaa cttttcaata gactctgaac tatctgtcag aggttgccaa
     3901 tttaattcag cgatatcatc ataaaggaaa agtaaatttt ttaagttcca gacgaggtca
     3961 acttcaacta tgtcgccctc ctgacctgga ttatagactc tcacagtata accatccgct
     4021 tcttctgtta cttcgctagt cacatctgct agttctgcac cgtttttcgc ggcctgaatc
     4081 tttggatgag ggtcaatgtc aaacccgcta ggcatcttac cagcacgtcc aagtcccacg
     4141 atttggccct taaagtcctc ctcaaactgg taaactatct tctgtctaaa ctctgccgta
     4201 ttatctgcat gaatatacaa atccccttga taagagttta tcttgaaatc aatggcaaaa
     4261 acagagagtg gaagaaggca aaacaagcct aacaccagta agaaaaaagt ttttttcatc
     4321 aactaagccc cctttttatc tttcttatca ttatagcatt ttttcgtaag taaaggctta
     4381 cttatgttga aaaattacgc atttttcgat aaaataggag acagttattt tttaatagat
     4441 cagaatagga gaaatcatga gaaaaatata cttatctatt ttcacaagtc tcttgctgat
     4501 gctaggactt gtcaatgttg ctcaagccga tgaatattta cgcatcggga tggaagcagc
     4561 atatgctccc tttaactgga cccaggatga tgatagcaac ggagctgtca aaatcgatgg
     4621 gaccaatcag tatgccaacg gatacgatgt tcaaatcgcc aagaaaatcg ctaaggactt
     4681 aggtaaagaa cctttggttg ttaaaaccaa gtgggaaggt ctagtccctg cccttacttc
     4741 tggtaagatt gacatgatta tcgcaggtat gagtccaact gcagaacgca aacaagaaat
     4801 tgccttttcg agcagttact acactagcga accagttcta ctggtcaaaa aagattctgc
     4861 ctatgcaaat gctaaatctt tggatgactt taatggtgcg aaaatcactt ctcaacaagg
     4921 tgtctacctt tatgacttga ttgcacaaat cacaggtgct aaaaaagaaa cagccatggg
     4981 agacttcgct caaatgcgcc aagctcttga ggctggtgtc atcgacgcct atgtttctga
     5041 acgcccagaa gctctgactg ccgaagccgc taactctaag ttcaagatgg tccaagtaga
     5101 accaggtttc aaaactgggg aagaagatac agctatcgcc attggacttc gtaaagatga
     5161 cactcgtatt agccaaatca atgccagcat tgaaaccatt tcaaaggacg accaagttgc
     5221 cctgatggat cgtatgatca aggaacaacc tgccgaagct acaacaactg aagagactag
     5281 cagtagtttc tttagccaag ttgctaaaat tctttctgaa aactggcaac aactcttgcg
     5341 tggtgctggt atcactcttt taatctctat cgtcggaacc atcacaggtc tcattattgg
     5401 acttgccatt ggtgttttcc gtactgctcc tctctctgaa aacaaagcca tttacggcct
     5461 acaaaaacta gtcggctgga ttctcaacgt ctacattgaa attttccgtg gtacgccaat
     5521 gattgttcaa tcgatggtta tctactatgg aactgcccaa gctttcggga tcaaccttga
     5581 ccgtacactg gctgctatct tcatcgtttc aatcaatacc ggtgcctaca tgactgaaat
     5641 cgtccgtggt ggtatcctag cagttgacaa gggacaattt gaagctgcga ctgctcttgg
     5701 tatgacccat aaccagacca tgcgtaagat tgtcctacct caggtagtcc gtaacatcct
     5761 acctgcaact ggtaatgaat ttgtcatcaa tatcaaagat acatctgtat tgaacgttat
     5821 ctctgttgtc gaactttatt tctcaggaaa taccgtggca acacaaacct atcaatactt
     5881 ccagacattt acaatcatcg ccgtgattta ctttgtcctc accttcaccg taacacgtat
     5941 cctacgattt atcgagcgcc gaatggacat ggatacctat actacaggtg ctaaccaaat
     6001 gcaaacggag gatttgaaat aatgacacaa gcaatccttg aaattaaaca cctcaaaaaa
     6061 tcctatggac aaaacgaagt gctaaaagac atttcactca ctgtccacaa gggagaggtc
     6121 atctctatca tcggaagctc tggaagcgga aaatcgacct tcctacgctc cattaaccta
     6181 cttgaaacac caactgatgg acaaatcctt tatcatggac aaaacgtcct cgaaaaaggc
     6241 tatgacctca cgcaataccg tgaaaagttg gggatggttt tccaatcctt taacctcttt
     6301 gaaaatctca atgttcttga aaacacaatc gtcgctcaga caactgtcct aaaacgcgaa
     6361 cgcacagaag ctgaaaagat tgccaaagaa aacctggaaa aggtcggcat gggagaacgc
     6421 tactggcaag ccaaaccaaa acaactctca ggtggtcaaa aacaacgtgt ggccatcgct
     6481 cgtgccctct ccatgaatcc ggacgctatt ctctttgatg aaccaacatc agctctcgat
     6541 ccagaaatgg ttggagaagt cctcaaaatc atgcaggacc tggctcagga aggcttgacc
     6601 atgattgtcg taacccatga aatggaattt gcccgtgatg tctctcaccg tgttatcttt
     6661 atggataagg gcgtgatcgc tgaagaaggt aaaccagaag acctcttcac caatcctaaa
     6721 gaagaccgaa caaaagagtt ccttcaacgc tatctcaaat aaaaagaaaa ggctgcatca
     6781 accgtgcagt ctttttgctg tcctcaaaat gaaaaggcag attctctatc tctactactt
     6841 gaaggtcaag aatccgccgt tatccaaaga ttaatcttca aatttttcat aatttttttc
     6901 atagaaatca attaggccta gggctgtttc aaatgaaata ttttttactt ttgcacgacc
     6961 ctgcgccaga gcaatgatag acatttcacg cgcattcgtt tctttagaga tacggtagcc
     7021 tgtgattttc ttatcacgaa cccagccaac aactgattct actttttcaa agtttgactt
     7081 agccatgttt ttctcctatt ttcttcttta taatatttaa ttgtatacgt ttttactact
     7141 tttgtcaata aaaaaacatg tattcaacga aaataattag ttcagaattt tagcttcaga
     7201 attttcttac ttcctttttg aatccgataa tatataggtt ttactagtct ctacaccata
     7261 aatatttgct aataaaaata ctgtattatt accctcttaa ggtgcgaaat tattcaagtt
     7321 cttaaaaaat gcttctctat ttccgtaaga tagcttattt cttcgattta agaactgaag
     7381 atgatagttc taacctttag aaatccaagc cttcactagc tcaaaaactc ctatctttct
     7441 tcctcaataa atcatctgag agataggtat tccttatgtc cttcaaattc atcactcctt
     7501 tggatattga ggtgctagcc tagaagcaga cacccgatta tctaaaccat ccttaataaa
     7561 gatgacaaga cagataagct cagttaatta cttatatatc tttttaatat ggtatatttg
     7621 tcaacaaaaa gaaatcaaat catac
//
LOCUS       DAVKEV010000069         7545 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVKEV010000069 DAVKEV010000000
VERSION     DAVKEV010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7545
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.069"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(109..1275)
                     /gene="recA"
                     /locus_tag="VWZ68_001939"
     CDS             complement(109..1275)
                     /gene="recA"
                     /locus_tag="VWZ68_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEU9372919.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(1330..2586)
                     /locus_tag="VWZ68_001940"
     CDS             complement(1330..2586)
                     /locus_tag="VWZ68_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEU9372920.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(2671..3687)
                     /locus_tag="VWZ68_001941"
     CDS             complement(2671..3687)
                     /locus_tag="VWZ68_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEU9372921.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(3695..4213)
                     /locus_tag="VWZ68_001942"
     CDS             complement(3695..4213)
                     /locus_tag="VWZ68_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9372922.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(4203..4646)
                     /gene="tsaE"
                     /locus_tag="VWZ68_001943"
     CDS             complement(4203..4646)
                     /gene="tsaE"
                     /locus_tag="VWZ68_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEU9372923.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(4732..5352)
                     /locus_tag="VWZ68_001944"
     CDS             complement(4732..5352)
                     /locus_tag="VWZ68_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372924.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(5735..6598)
                     /locus_tag="VWZ68_001945"
     CDS             complement(5735..6598)
                     /locus_tag="VWZ68_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9372925.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEVKSNLSNFKHLSARLLDDRNYDDLEYLYKIEVERS
                     TFLTLEDRTYLEWIKSIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            7064..7288
                     /gene="pneA1"
                     /locus_tag="VWZ68_001946"
     CDS             7064..7288
                     /gene="pneA1"
                     /locus_tag="VWZ68_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="HEU9372926.1"
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIIL
                     KSAAASSKVCISAAVSGIGGLVSYNNDCLG"
     gene            7295..7483
                     /gene="pneA2"
                     /locus_tag="VWZ68_001947"
     CDS             7295..7483
                     /gene="pneA2"
                     /locus_tag="VWZ68_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="HEU9372927.1"
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFI
                     ASYLGSAQTRCGKDNKKK"
BASE COUNT         2290 a         1604 c         1251 g         2400 t
ORIGIN      
        1 ctaataaagt tgttcatatc ttatttcaag ctactatata taatatataa tctaaaaact
       61 tgaatcaaaa atcgaaaaag tagcggattt ctccactgct ttaacagctt attcttcaat
      121 ttcgatttca agttcatcgc ctaagtcaag cggaacttct tcattcactg cttcttcttt
      181 ctttggctca tcttttttgt tttcagtatc ttgttctgaa acttcttctc catcaatcaa
      241 gccaaattta gaacggactt gcttatcaat ttcatcaaag atttctgggt gctctgccaa
      301 gtatttctta gcattctcag aaccttgccc aattttttca tctttgtaag aataccaagc
      361 ccctgctttt ttgataatat ccaaatcgct tgcaatcttc aaaagctcac cagtcttaga
      421 aattccttct ccgtacataa tttcaactac ggcttcctta aacggtggag ctaccttatt
      481 ttttacaacc ttaatcttag tttctttacc gacattggtt tctttttgat caccagttcc
      541 cttaatttgt gtattaccac gaacatccaa gcggactgaa gcatagaatt tcaaagcacg
      601 tccgcccggt gttgtttctg gatttccaaa catcactcca actttttcac gcaattggtt
      661 gataaaaatg gcaattgttt tggttttatt gatagaggcg ccaagtttac gcatggcctg
      721 gctcatcata cgagcctgca aaccaacatg gctatctccg atatctccat caatttccgc
      781 acgaggaaca agggcagcaa ctgagtcgac tacgacaaga tcaactgcac ctgagtcaat
      841 caattttccc gcaatctcaa gaccttgctc tcctgagtct ggttgagaca agagcaattc
      901 gtcaatattg acaccaaggg ccgcagcata agctggatca agggcatgtt ccgcatcgat
      961 aaaggcagca atcccacctt ctttttgcgc ttgtgcaact gcatgaaggg caaccgttgt
     1021 cttaccagat gactctgggc catagatttc gatgatacgt cccttaggat aaccacctga
     1081 gccaagggca atgtcaagag ctaaagaacc tgagctcatc acttgcacct tttgctccgc
     1141 acgttcaccc aaacgcatga ttgatccttt accaaagtct ttctcaatca atttaagagc
     1201 gtcattcaag gccttttcac gttctgcccc aaattttttt gaaatttctt ctaatttttt
     1261 tggttttttc gccattctat tctcctacat tctaatgatc ctcagaccta tctactatta
     1321 tatcaaaagt tagtcactta ataaagcctt gcgaactagg ttaaaggcat gcataaccgc
     1381 aatgtgacgt acatctgctc ggcttctgcc tccaatatta accttgataa cctcagttcc
     1441 ttgatcttgc gccaagccta tgaagactgt cccaactggg tgtccttcta ggctatctgg
     1501 tcctgccact ccagtcaaac taattccaaa atcagactgg gtcttgcttc gtgcctgctc
     1561 agccatcttc tgagctgtaa attcagacac cacaccatgt tcttccaaat tcttggcagg
     1621 aatatccaac atccttgatt tttcctccaa gctataggtc acaaaaccac cctcaaatat
     1681 acttgaaact ccagaaaaat tcgccacggt agcttggaaa agacctgccg tcaaactctc
     1741 tgcagccgcg atggttttcc cttgcctttt cagttcttct accacaatgc tggctaaact
     1801 agtttcttcc ccataaccat agcaaaagtc tcgtaaagaa attccttcga aagtctggca
     1861 gtccaagatt tgattttcca agatatccag cgcttgattc gcctcttctt gactgctagc
     1921 ctttgttgac agacgtagag tgacttctcc tgtcttggca taaggggcca aggtaggatc
     1981 gatctgatta tcaattaaat cagccaaaat cgtaaccaac tggctctcgc caatcccaaa
     2041 gaaacgaaga actcgggaat acagcttgct ccctgtcatc aacttgggta gaagttggtt
     2101 taagaccatg ggtttcaatt cacttggcgg acctggaagg acgacatagg tcactccgtc
     2161 tacttctaat tttcctccaa cagccagtcc tgtttcgttt ggcagtggaa tcgctccttc
     2221 tacaatttga gcttgtcttt cgttattcgg tgttcgggca tagtctggtc gcagggcaaa
     2281 aaagatatcc aacttctcct gagcctgagg atcaaagact aatgctttcc ctaaaaattt
     2341 agctagggtt tgtttggtta ggtcgtcctc agttggcccc aaaccgcctg tcaaaatcac
     2401 cagactgcta cgttgactgg caatctcaag caaagacaag agacgaactt cattgtctcc
     2461 tacagccgtc tgaaaatata catctacccc aatctcagct agtttttccg acaaaaactg
     2521 ggcattggtg ttgacaatct gtcctgtcaa aatctctgtt ccaacagcaa tgatttctgc
     2581 tttcatgttt cctcctacct atctattcgt atttttttga aaaaatcgca ggaattttcc
     2641 tacgattgat ttttttattt gtatcaaaag ttaattatct tcatcaccaa caggtgctct
     2701 gccaaataaa tcttcaaata aaaccgcatt ggtttcaagc tgagtaactt cttcttgtcc
     2761 caaagaacgt cggagtatat tttgcatttc caacatatgt gctctcgaaa caatctggta
     2821 agaaacacct tgaagtatct ctccttcacc ctgcaactgc tgagtttcaa tggttttaaa
     2881 tgaatcttta tagcctagca agttagggat actttttgca gacaaatcaa tattggtctg
     2941 catattgtca ctcaaagctt ttagaatctc ttgataatga ccaatgctat ttaaactgag
     3001 agctttttcc atgacttttt gaataacttc acgttgacgt ttttgacgac cataatcccc
     3061 ctcaggatct tggtaacgca ttcgtgcata gactagggct tcttctcccc caatatgttg
     3121 ctccccaaca ccgatagaaa tggtattaaa ttcttcttgg tcactgatag aaattgggaa
     3181 acctaggata ttattgactg taatacctcc tactgcatcc actaattttt gcaaccctct
     3241 catattgacc atcacatagc gatcaatatg gatattcatc attttttgaa tggtttctat
     3301 agcaagctct gctccaccat ctgcatatgc tgagttcagt ttcgcttcat gagcctgacc
     3361 attccctgat tcaatgcgcg tcagaatatc ccgctctaaa ctcatcattg ttgttttttt
     3421 cgttttagga ttcactgtca tcaagatcat gctatcactt ctaccgaccc aagtttcagt
     3481 tcgttcaaca tttccggtgt ccactcccat taacagaatg gttagaggtt cagtcgcttc
     3541 aataaccttg gtttcttcac cgattttttt ataggtttta gctaaggttt ctgtcccttg
     3601 ttgataaata gtataagcaa aaacacctac tcctactaca gttacagaaa gtaaagctag
     3661 caccattcca ataatttttt taaccatatt tctactaacc tatcagttta cccatcaagt
     3721 aaacatcgat aaatttccct tcttctatat atgccccacg ctcttggcta ccttcaatga
     3781 caaagccatg cttttgataa agatggactg ctgcttgatt acgagtttgg acagtcagtt
     3841 ggagacgacg cagaatgcca cttgcttgtg cccactctat cgcttcttct agcaacaaac
     3901 ttcccaagcc attattccaa tatctttttc caatcacaat gaagagatct ccaatatgac
     3961 ggactctctt acgctgatca gctgtaatat ttacaatacc agcaattttg ccatttaaga
     4021 atgcaagtaa ggttatctga ttgtccgaac tagcttgctt gttgaggaat atttccatct
     4081 cctcactagt caagagaata ccatctccgt ctaggctggt aaagtctgtc tccaaactca
     4141 cacgatttaa aaaggccact aattcagctg catctttggg ctctgcttcc ctaatgagca
     4201 attcatactc catattgaag ctcctctaac aatttctcag cacgcaaacc ctttgcctga
     4261 aaatttaaac ggcgtccatc tgcttctttt agaatttcca attctaaata agcatctggc
     4321 aaggcatctc ctaagagatt tccccactca ataacagtca cgccgccacc aaagataaac
     4381 tcatccaagt cgatagaatc agcatctcct tcaatacgat aaacatctag gtgataaagt
     4441 ggaagtcgac cttcatactc tctcacgata gtataggtgg gacttttaat catttgagaa
     4501 atctgtaatc cttttgcaag tcctttagta aaggtcgttt tacctgcacc cagttctcca
     4561 gttaagatta aaacatcatt ctttgctaat agatggccca aacgctcccc taaggcttgc
     4621 aactcttctt cattttttgt gtacatactc ttattatacc aaaaactttt cttttgtgtc
     4681 tattttccta ctaaacttat catcataaca tccataaaaa acaggctttc tctaaaagaa
     4741 aatgagcgta acaatgacca atacaagatc tcggaaaata tgaccataaa aggaaacttc
     4801 cttcttaacc gaatttggga caagataggc tgcaaaaaac aagcccagtc caatataaat
     4861 cagaagtgag acaatggtca ttggatttct taagaaaaga agtgttgcta aaatagtcac
     4921 caacactgtc ttttttctgt ccagcatagc aagaaaatcg cgcacgtatt ttttcaaggg
     4981 taaaaaaatc agcaaatcta gcccaaatag gaaaaagaag gatggcaata aaaagtcaac
     5041 taattcttgc tgcagcgtat ttttgatgaa caagttatct gacaaaacaa gaacagctcc
     5101 taacaaatta attaagagta acatactgta aaaaagcttc accgacttct tactggctag
     5161 gacactatgg acttcttgct tacgggtata aagataattt actccagcac agattcctga
     5221 aacgaaaacc atgcttccga tgaaaaaagc tgtactttgt ttaaaggaca agatgcattc
     5281 cttccatagg aaacagctac tcaaactgat ttgaattaaa gctaacaaaa ataagattct
     5341 cattgatttc atcttctctc tcccttccta ccaatcatta tactaggaga aaagagagaa
     5401 ctgtttctaa tcttctcaaa tgtctcttta agacgctaaa caaacactag agactaatac
     5461 tcaatgaaaa tcaaagatca aactaggtag ctagccacag gttgctcaaa acagtgtttt
     5521 gagattgcag atagagctga cgtgatttga agagattttc gaagaatata aatttgaaat
     5581 catgaaaatc cgtcaaacgg gtgattgttt tgtctcgcac ctcacggagc gagacggact
     5641 cagagtcaca taattataag gctgatagta ttaatctaac tatcagcctt acaggttatt
     5701 taacgtttca gaaaaactat aatgtcaaga ttaactaaac agtatctagt tccttcaaat
     5761 aattttctat cttcatcaac attaaaggat tgttataaat cttacataac tctcttgctt
     5821 ctatataata atttttgact tgttctctgt ctagaaattt ggctccagca tttcctacaa
     5881 gaataagtag aggagccaat tggtagcttg tctgtctttg tttacagagt tcaatcgttt
     5941 caagagcttc ttggatggct tcattatatt tttcctttga tactaggtag tgagcgtagt
     6001 tgtaacgaac tctgatgtag ccaaataaaa actcttgatg gtccaaattt tttgtctgat
     6061 acaactctat taaatgagag tagtttgcct catattcttg ttcacgaccc actaaggaat
     6121 agaaattaga tagagtattc aacgccttta aataaatcag agtatttgaa gagactttta
     6181 ataatatatt ttccaatgac gaaattgcct cacacttact gtcatattga tagaagtcaa
     6241 ttatagattt aatccattca aggtaagttc ggtcttctaa tgttagaaaa gtgcttcgtt
     6301 ctacctctat tttataaaga tattctaaat cgtcataatt tctgtcatct aataggcgag
     6361 cagatagatg tttgaaatta gagaggttag acttaacttc gatttgttca ttgaaaaagt
     6421 aatccaaagg gacttcaagt cgttgagaga gtttgaataa caagtctgcg gagggaataa
     6481 aatgacctct ttcaatttta ctaatctggc tttgttcaca aattccttct gcaagagttt
     6541 gttgggagag tctcaactct tttcttttca atctgaattt ctctgcgagt gtattcatta
     6601 aagataataa accttcctat ttgcttaatt tcattataaa gtttttagtt caaaatagca
     6661 agttaaagga ataaataatt ctttatggta ataaacaaaa aaaaaaagtt aaaaattaca
     6721 taaaaatact tgactaaata aaatatatct gttagaataa aaacaaggaa aaagaaaggg
     6781 gtttcattgc atgagaaaaa aacgtggaat taaaaaatta gttacatttg cattgctagg
     6841 tgtttttatg tttagtaata caattcctta ccaacagttt attcagaaga ataaacaatt
     6901 ggagattcga gtgcaatcgc aaaagaagtc caatggtctt gatgttggga aggcggatta
     6961 aaacccgata ttttgcacga gaatgagaga attataattt atctgaaaaa acgaaaaata
     7021 tagagcaact tatttaactt tttataagga ggagttatta cttatgacca actttaattc
     7081 aaacgaaaaa ttttgtggaa aaagtttaaa atcattgtct gctgatgaaa tgagtttaat
     7141 ttatggtgca tctgatggtg cagagccacg ttggacgcct actcctatta ttttgaaatc
     7201 agctgcagct agctcgaaag tatgcattag tgcagctgtt tctggtattg gggggctagt
     7261 tagctacaat aatgattgtt tggggtaaat taaaatgaaa aatgattttg taattggaaa
     7321 gagtttgaaa gaattatctc ttgaagaaat gcaattggtt tatggtggca cagatggtgc
     7381 tgaccctaga tcaacaatta tatgttctgc tacattaagt tttattgcat catatttggg
     7441 gtcagctcag actcgttgtg gcaaagacaa caagaaaaaa taaaatattc aattttaaaa
     7501 ataaaagttg ctctttattt tcctctctcg taactaataa ttttg
//
LOCUS       DAVKEV010000070         7233 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVKEV010000070 DAVKEV010000000
VERSION     DAVKEV010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7233
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.070"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..177
                     /locus_tag="VWZ68_001948"
     CDS             <1..177
                     /locus_tag="VWZ68_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372928.1"
                     /translation="AEALLEKVTDSSIRQNAVETLTGLKSSLLLGTKDNNTISAEVDS
                     LLALLKESQPTPIQ"
     gene            387..3506
                     /gene="phtE"
                     /locus_tag="VWZ68_001949"
     CDS             387..3506
                     /gene="phtE"
                     /locus_tag="VWZ68_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEU9372929.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQISQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLKEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            3732..4292
                     /locus_tag="VWZ68_001950"
                     /pseudo
     CDS             3732..4292
                     /locus_tag="VWZ68_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            4397..4745
                     /locus_tag="VWZ68_001951"
                     /pseudo
     CDS             4397..4745
                     /locus_tag="VWZ68_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(5016..5237)
                     /locus_tag="VWZ68_001952"
     CDS             complement(5016..5237)
                     /locus_tag="VWZ68_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372930.1"
                     /translation="MDLFQELICLVQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            5202..5831
                     /locus_tag="VWZ68_001953"
     CDS             5202..5831
                     /locus_tag="VWZ68_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372931.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSANSKDKTALLESTKAILVLNHQIQSKVSASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            complement(5867..7090)
                     /gene="pepT"
                     /locus_tag="VWZ68_001954"
     CDS             complement(5867..7090)
                     /gene="pepT"
                     /locus_tag="VWZ68_001954"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEU9372932.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
BASE COUNT         2585 a         1256 c         1379 g         2013 t
ORIGIN      
        1 gcggaggcct tgctagaaaa agtaacagat tctagtatta gacaaaatgc tgtggagaca
       61 ttgactggtc taaaaagtag tcttcttctc ggaacgaaag ataataacac tatttcagca
      121 gaagtagata gtctcttggc tttgttaaaa gaaagtcaac cgactcctat acagtagtaa
      181 aatgaatgga gcatatttta tggagaagta acctttcgtg ttacttctct tttttagaaa
      241 aacgtaacag aaacttgaca aaagtaattt taaatagtaa actatttact ggttaattaa
      301 atggttaaat aaccggttta gaaaactatt taataaagta aaagaagttg agaaaaaact
      361 tcatcattta ttgaaatgag ggatttatga aattcagtaa aaaatatata gcagctggat
      421 cagctgttat cgtatccttg agtctatgtg cctatgcact aaaccagcat cgttcgcagg
      481 aaaataagga caataatcgt gtctcttatg tagatggcag ccagtcaagt cagaaaagtg
      541 aaaacttgac accagaccag attagccaga aagaaggaat tcaggccgag caaattgtaa
      601 tcaaaattac agatcagggc tatgtaacgt cacacggtga ccactatcat tactataatg
      661 ggaaagttcc ttatgatgcc ctctttagtg aagaactctt gatgaaggat ccaaactatc
      721 aacttaaaga cgctgatatt gtcaatgaag tcaagggtgg ttatatcatc aaggtcgatg
      781 gaaaatatta tgtctacctg aaagatgcag ctcatgctga taatgttcga actaaagatg
      841 aaatcaatcg tcaaaaacaa gaacatgtca aagataatga gaaggttaac tctaatgttg
      901 ctgtagcaag gtctcaggga cgatatacga caaatgatgg ttatgtcttt aatccagctg
      961 atattatcga agatacgggt aatgcttata tcgttcctca tggaggtcac tatcactaca
     1021 ttcccaaaag cgatttatct gctagtgaat tagcagcagc taaagcacat ctggctggaa
     1081 aaaatatgca accgagtcag ttaagctatt cttcaacagc tagtgacaat aacacgcaat
     1141 ctgtagcaaa aggatcaact agcaagccag caaataaatc tgaaaatctc cagagtcttt
     1201 tgaaggaact ctatgattca cctagcgccc aacgttacag tgaatcagat ggcctggtct
     1261 ttgaccctgc taagattatc agtcgtacac caaatggagt tgcgattccg catggcgacc
     1321 attaccactt tattccttac agcaagcttt ctgccttaga agaaaagatt gccagaatgg
     1381 tgcctatcag tggaactggt tctacagttt ctacaaatgc aaaacctaat gaagtagtgt
     1441 ctagtctagg cagtctttca agcaatcctt cttctttaac gacaagtaag gagctctctt
     1501 cagcatctga tggttatatt tttaatccaa aagatatcgt tgaagaaacg gctacagctt
     1561 atattgtaag acatggtgat catttccatt acattccaaa atcaaatcaa attgggcaac
     1621 cgactcttcc aaacaatagt ctagcaacac cttctccatc tcttccaatc aatccaggaa
     1681 cttcacatga gaaacatgaa gaagatggat acggatttga tgctaatcgt attatcgctg
     1741 aagatgaatc aggttttgtc atgagtcacg gagaccacaa tcattatttc ttcaagaagg
     1801 acttgacaga agagcaaatt aaggctgcgc aaaaacattt aaaggaagtt aaaactagtc
     1861 ataatggatt agattctttg tcatctcatg aacaggatta tccaagtaat gccaaagaaa
     1921 tgaaagattt agataaaaaa atcgaagaaa aaattgctgg cattatgaaa caatatggtg
     1981 tcaaacgtga aagtattgtc gtgaataaag aaaaaaatgc gattatttat ccgcatggag
     2041 atcaccatca tgcagatccg attgatgaac ataaaccggt tggaattggt cattctcaca
     2101 gtaactatga actgtttaaa cccgaagaag gagttgctaa aaaagaaggg aataaagttt
     2161 atactggaga agaattaacg aatgttgtta atttgttaaa aaatagtacg tttaataatc
     2221 aaaactttac tctagccaat ggtcaaaaac gcgtttcttt tagttttccg cctgaattgg
     2281 agaaaaaatt aggtatcaat atgctagtaa aattaataac accagatgga aaagtattgg
     2341 agaaagtatc tggtaaagta tttggagaag gagtagggaa tattgcaaac tttgaattag
     2401 atcaacctta tttaccagga caaacattta agtatactat cgcttcaaaa gattatccag
     2461 aagtaagtta tgatggtaca tttacagttc caacctcttt agcttacaaa atggccagtc
     2521 aaacgatttt ctatcctttc catgcagggg atacttattt aagagtgaac cctcaatttg
     2581 cagtgcctaa aggaactgat gctttagtca gagtgtttga tgaatttcat ggaaatgctt
     2641 atttagaaaa taactataaa gttggtgaaa tcaaattacc gattccgaaa ttaaaccaag
     2701 gaacaaccag aacggccgga aataaaattc ctgtaacctt catggcaaat gcttatttgg
     2761 acaatcaatc gacttatatt gtggaagtac ctatcttgga aaaagaaaat caaactgata
     2821 aaccaagtat tctaccacaa tttaaaagga ataaagcaca agaaaactca aaacttgatg
     2881 aaaaggtaga agaaccaaag actagtgaga aggtagaaaa agaaaaactt tctgaaactg
     2941 ggaatagtac tagtaattca acgttagaag aagttcctac agtggatcct gtacaagaaa
     3001 aagtagcaaa atttgctgaa agttatggga tgaagctaga aaatgtcttg tttaatatgg
     3061 acggaacaat tgaattatat ttaccatcgg gagaagtcat taaaaagaat atggcagatt
     3121 ttacaggaga agcacctcaa ggaaatggtg aaaataaacc atctgaaaat ggaaaagtat
     3181 ctactggaac agttgagaac caaccaacag aaaataaacc agcagattct ttaccagagg
     3241 caccaaacga aaaacctgta aaaccagaaa actcaacgga taatggaatg ttgaatccag
     3301 aagggaatgt ggggagtgac cctatgttag atccagcatt agaggaagct ccagcagtag
     3361 atcctgtaca agaaaaatta gaaaaattta cagctagtta cggattaggc ttagatagtg
     3421 ttatattcaa tatggatgga acgattgaat taagattgcc aagtggagaa gtgataaaaa
     3481 agaatttatc tgatctcata gcgtaaggaa tagcagtaga aaaagtctga atcaaaaatg
     3541 aagttctctc aaaagttaga aataaaactc tgactttggg agaatttcat tttattatta
     3601 atatataaaa tttcttgaca tacaacttaa aaagaggtgg aatatttact agttaattaa
     3661 ttggttaatt aatttctata atcatttaat aatgaagaca tcatataaat aattatagaa
     3721 atgaggtaat tatgaaattt aaaaagaaat atatagcagc tggatctgtt gttatccttt
     3781 ccttaagtct gtgtgtttat gctctgaacc aacatagcta acaggccaat acagataaaa
     3841 atcgtgtttc atatgtaaac agtaataaag acactaagaa gactgaaaat ttgactccag
     3901 actaggttag tcaaaaagaa ggaattcaag caaaacaaat tgttattaag attacagatc
     3961 aaggttatgt aacttctcat ggcgatcatt atcactacta taatggtaaa gttccttttg
     4021 atgcgctctt tagtgaagag ccattaatga aagcccccaa ctatcagccg aaagatcaag
     4081 atattgtcag ttaggttaag ggaggatata ttattaaggt agatggaaag tattatgttt
     4141 accttaaaga tcaagctcat gcagaaaatg tacgaacaaa agatgaaatc aatcgccaaa
     4201 aacaagaaca tggtaaagac gataaaggag ctagtgcaga agtatctgta gcaaaattac
     4261 agggacgtta tactaccgat gatggttata tatagtgagt tgaatttaga atagcacatc
     4321 atagtttcta aatcattgtt agaaattact ttaaaatccc cttatcaatt tgctcatatt
     4381 ctatttcaat ctactaatag taccacatgg tggtcactat catttcattc ctgagagtga
     4441 cttgtcggca ggtgaattag cagccacata tgtctttaac cctaatgata ttgtcagaga
     4501 tataggtgat gcttatatag taagacatgg ggaacactat cactatattc ctaagtcatc
     4561 tcttaacaat cccccatcac actctaacac ggaagaggta ggaagttctt ctagttctgt
     4621 attaagtaat ccgtcactac atgtccacca tgaggaagaa gatggtcatg gtttttgatg
     4681 ccaatcgaat tataagtgaa gattcagaag gttttgtgat tcctcatggc gaccacaatc
     4741 actacatcaa ggttcaaact aagggatatg aagcggcttt gaaaaacaag attccatccc
     4801 tgcaatccaa ctatcaacct ggaacttttg atgagaaggc agtcttggca aaagtagatc
     4861 aacttctagc tgatagcaga agcatctaca aagacagatt gagttagctt taggtcagtt
     4921 tactgaaagt ttgaaaaaaa taaaagttag ttgattgatt acttctctaa attttgggca
     4981 cactaaaaag aggtcttgac acctaaactt taaaattaaa gcatattgaa tccgtgctgc
     5041 tgtgcgaagc gaatagcgtc ttggacgaac attgtcttat ctggatttct tatttctgta
     5101 aggccttgta atcttggatt ataactctcc tgttttagga gtacatggta gatagcaacc
     5161 aataatctgc gacagatagc aaggaagaag tagaaagtct tttgaacaag gcaaatcaac
     5221 tcttggaaca aatccatgaa gaaggaatca gacaatcctt ggcagaagaa gtagaaaatc
     5281 taaaagctgc cacaaacaag gctgatgcag acttggatga agtaaacagt caggtaaaag
     5341 atgttttgac tcgtatcgct agcgcccttc aacaagaaaa ggaaaatgct gagcaagatt
     5401 ctcagacact tgtactctat caaaaactct acgatattct catgtcgctt cactcttatt
     5461 tagaaagtaa taatggatct gatgcggact ttgataaggt ggatgcatta ttagatcaac
     5521 tttctgctaa tagtaaagac aaaacagctt tacttgaatc gacaaaagct attctagttt
     5581 tgaatcatca aatccagtca aaagttagcg caagtgaaga aacaagtcca gcaagaaatg
     5641 ctgaagcaaa tagtgataac accagtgctg agaaccaacc aaacgcaact gcagaatcta
     5701 acattgaaac tgctagcgac gaaaacaaac caagcaatac aagagattct aaacctgctg
     5761 aatcaacttc agaaaatgaa acaacagaat cttctacaac tactggaaat caagaaaaac
     5821 cagtagaata aaaagaaagg cgaagtagct gagccacctc gtctttttag cctttataag
     5881 ctacgatgcc aatgatggta tcaactgcac gttccatagt ctgaaggcta acgtattcaa
     5941 aacgtccgtg catattttcg ccacctgcaa agatattcgg agttgggatt cccataaagg
     6001 aaatcttaga gccgtctgtt ccaccccgga ttggttcgat aataggcgtg atacctagat
     6061 cttccataac ggctttagca atggtaattg gagtcatatc tttttcaatg acttctttca
     6121 tattgtagta ctggtctgtc aagttgagag tgacacggtc gctcccaagt tcttcattca
     6181 tcttatcagc gatagattgc atggatgctt tacgcgcttc aaaggcatct ttttcaaaat
     6241 cacgaatgat gtagcttgca cgcacctcct caacactacc tgtcacatcc attagatggt
     6301 aaaaaccttg gtaaccttca gttaactcag gtcggtcatt ttctggaagt tgattatgaa
     6361 aatcaattgc tagctgaagg gcattgacca tctgcccttt ggcagtacca gggtggacat
     6421 tacggccttg gaaatgcaat tcagcaccag cggctgagaa agtctcgtac tgaagttcac
     6481 ctagtggacc accatcaaca gtgtaggcaa aatccacatc aaaatcttct gcatcaaatt
     6541 tattggcacc aacaccgatt tcttcatctg gaccaaaacc aacacgaatc tcacagtgct
     6601 taatttcagg atgagcagtt agatattcaa tggctgtcat aatttcagca attcctgact
     6661 tgtcatcagc acctagcaag gttgttccat ctgttgtgat gagtgtttgt cctggatatt
     6721 tttcaagact cttgaagtcg gctggatcga gtttgaaacc agaattccct agttcaatca
     6781 caccaccatc gtagttttca attacctgtg gattgactcc ttcagcatta aaatcagcag
     6841 tatccatgtg cgatataaaa ccaatcttac gtgttaaaga cggatcgttg gctggcaagg
     6901 ttccaatagc aaaaccattc ggtagatagt aaacattttg cagtccaaca cgtttcattt
     6961 caggaattag gacatttgtt gcgaagtcaa cctgactctg tgtacttgga gtagtagtag
     7021 agtgttcatc agagcgcgtg ttgaccttaa cgtaggttaa gaagcggtcc aagagatttg
     7081 gataagtcat aaaaaaactc cttttttatc ataaaataga atacaaaact tcggaaaaat
     7141 atgatttgag aaattttatg aattttgaaa aaatataata attcaaattc agaagacttt
     7201 caaaagaaat tttcgagcga ttagaataaa tat
//
LOCUS       DAVKEV010000071         7171 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVKEV010000071 DAVKEV010000000
VERSION     DAVKEV010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7171
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.071"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..595
                     /locus_tag="VWZ68_001955"
                     /pseudo
     CDS             1..595
                     /locus_tag="VWZ68_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            719..2025
                     /locus_tag="VWZ68_001956"
                     /pseudo
     CDS             719..2025
                     /locus_tag="VWZ68_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(2213..3775)
                     /gene="guaA"
                     /locus_tag="VWZ68_001957"
     CDS             complement(2213..3775)
                     /gene="guaA"
                     /locus_tag="VWZ68_001957"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEU9372933.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3917..4615
                     /locus_tag="VWZ68_001958"
     CDS             3917..4615
                     /locus_tag="VWZ68_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9372934.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERHVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4658..5554)
                     /locus_tag="VWZ68_001959"
     CDS             complement(4658..5554)
                     /locus_tag="VWZ68_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU9372935.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQTDIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5563..6498)
                     /locus_tag="VWZ68_001960"
     CDS             complement(5563..6498)
                     /locus_tag="VWZ68_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEU9372936.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLSQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6495..>7171)
                     /locus_tag="VWZ68_001961"
     CDS             complement(6495..>7171)
                     /locus_tag="VWZ68_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="proteinase"
                     /protein_id="HEU9372937.1"
                     /translation="RKLNETFYIETLGMKALLEESAFLSLGDQTGLEKLVLEEAPSMR
                     TRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQNGYAFEIFSPEDDLILIH
                     AEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDIESFLESSEIGASLDFIP
                     AQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYFIPKSEKFFLCKDRNNVE
                     LWFEEV"
BASE COUNT         2257 a         1542 c         1298 g         2074 t
ORIGIN      
        1 aacaaaacca agaaaagttg atagagatag acttaaaaac tatcttactg acaatccaga
       61 cgcttatttg actgaaatag cttctgaatt tggctgtcat ccaactacca tccactatgc
      121 gctcaaagct atgggctaca ctcgaaaaaa aagaaccaca cctactatga acaagagcca
      181 gaaaaagtag ccttatttct taagaatttt aatagtttaa agcacctagc acctgtttag
      241 attgatgaaa caggattcga tacttatttt tatcgagaat atggtcgctc attaaaaggt
      301 cagttaataa gaggcaaagt atctggaaga agatatcaga gaatttcttt ggttgcaggt
      361 ctaacaaatg aatggtgagt taatcgctcc aatgacttac gaagagacga tgacgagcga
      421 cttttttgaa gcttggtttc agaagtttct cttaccaaca ttaaccacac catcagttat
      481 tattatggat aatgcaagat tccatagaat gggtaagtta gaactcttgt gtgaagagtt
      541 tgggtataaa cttttacctc ttcctcccta ctcacctgag tacaatccta ttgaggctct
      601 ataatatttg tagtgggtaa atcccctatg gatattatgg agcctatttt tgtgtagaaa
      661 aaaagtccca taagatctat aatgaaaagc gatcaaacaa ctcattagaa agattcatat
      721 ggaacaatta cattttatca caaaattact agacattaaa gaccctaata tccagatttt
      781 agacatcatc aataaggata cacacaagga aatcatcgcc aaactggact acgacgcccc
      841 atcttgccct gagtgcggaa gtcaaatgaa gaaatatgac tttcaaaaac cttctaaaat
      901 tccttatctt gaaacgactg gtatgccttc tagaattctc cttagaaaac gccgtttcaa
      961 gtgctatcac tgttcaaaaa tgatggttgc tgagactccc ctggtaaaga agaatcacca
     1021 aatccctcgt atcatcaacc aaaaaattgc tcaaaagtta attgaaaaga tttctatgac
     1081 tgatattgcc catcagcttt ccatctcaac ttcaactgtt attcgtaagc tcaatgattt
     1141 tcactttaaa catgattttt cgcgtcttcc tgagattatg tcttgggatg agtatgcttt
     1201 tacaaaggga aagatgagct tcattgcgca agattttgaa aagctcgata tcatcactgt
     1261 tcttgagggt agaacacaag ctatcattcg aaatcacttt cttcgctacg atagagttgt
     1321 ccgatgtcgc gtcaaaatta ttactatgga tatgtttagc ccttactatg acttagctag
     1381 acagcttcgc tttcaaattt ctaggctcag gctgaaacag tctcccagac tgtttcactc
     1441 ccgaatgcta aaatcgttct tgatcgcttt cacattgtgc aacatcttag ccgtgctatg
     1501 agtcgtgtgc atgttcaaat catgaatcag tttcatcgaa aatcccatga atacaaggct
     1561 atcaagcgct actggaagct catacaacag gatagccgta aactgagtga taagcgtttt
     1621 tatcgtccta cttttcgtat gcacttaacc aataaagaga ttttagacaa gcttttgagc
     1681 tattcggaag acttgaaaca ccactatcag ctctatcagc tcttgctttt tcacttccag
     1741 aataaggaac cagagaaatt tttcggactt attgaggaca atctgaagca ggttcatcct
     1801 atttttcaga ctgtctttaa aaccttcctc aaagataaag aaaagattat caacgccctt
     1861 caactaccct attcaaacgc caaattggaa gcgaccaata atctcatcaa acttatcaag
     1921 cacaatgcct ttggttttcg gaactttgaa aacttcaaaa aacggatttt tatcgctctg
     1981 aatatcaaaa aagaaaggac gaaatttgtc ctttctcgat cttagctttt cttcaaccca
     2041 ctacagttga caaagagcct gaaaactacg gtctaatttt ttgtccaaat gtaaaccact
     2101 tggaactatt attcaattta ttctttttag caaatgttcc cgttttaatc ccagttacag
     2161 tttttaatcc tttgtaaccg ttgattttac aaagctttta atttttttgc gattactccc
     2221 actcaactgt tgcaggtggt ttacttgtaa tatcgtagac gatacggtta acatgatcca
     2281 cttcatttac gatacgtact gagatttttt gaagtacttc ccatggaatt ttggcaaaat
     2341 cagcagtcat accatcgata gaagtgatag cacggattgc aatcgtgtag tcatacgtac
     2401 gaccgtcacc cataacaccg actgaacgaa cgcctgtgtt aacagtgaag tattgccaaa
     2461 tatcgcggtc aagtccagct ttagcgattt cttcacgaag aatagcgtct gattcacgaa
     2521 cggtttcaag tttctcttca gtgatttcac ccatgacacg gatagcaagt cctggtcctg
     2581 ggaatggttg gcgccatacg atatggtctg gcataccaag ctctgtacca agagcacgaa
     2641 cttcatcctt gtaaagagta ttgagtggtt caatcaattc aaactgcata tcttctggaa
     2701 gaccacccac gttgtggtgt gacttgatag tttgagctgt atccgtacca gactcgataa
     2761 catctgtata taaagtacct tgagcaagga atttcacatc tttgagcttg cttgcttcgt
     2821 catcgaatac atagacaaac tcgttaccga tgattttacg tttttgttca gggtcagaaa
     2881 cgccagcaag tttgtcaagg aaacgtttag cagcgtctgc tttgacgata ttcaaaccaa
     2941 acttaccacc gagcatgtcc ataacttgat cagcttcgcc tttacgaaga agaccgtggt
     3001 ccacgaagat acagatcaat tgatcgccaa tcgctttttg gagaagaacc ccaacgacag
     3061 atgagtcaac accacctgat agaccaagaa ggacacgttt atcaccgacg gtttcacgaa
     3121 tttttttgat ctgcatgtca atgaaattat ccattgacca gtcaccttta gccttacaaa
     3181 tgttaagggc aaagttacga aggatatcat ttccgtatac agaatgacga acttctgggt
     3241 ggaattggat accgtaaatg tgtttatctg ggttttcgat ggctgcgtat gggcagtcag
     3301 ctgatgtacc tgtacgaaca aagtcagcag gaatctcagt aaccgcatca ccatggctca
     3361 tcaaaacagt ctgttcatca ggtgttgatt caaaaagcgc tgatggtgtg tgagttaggg
     3421 ttgattgacc gtattcacga tttccagcat cacctgcagg aacaactttt cctccaagtt
     3481 tatgggtcaa taactgcata ccataacaga ttcccaaaat tggaattccg agttcgaaga
     3541 tttctgggtc aatatcaaat gaaccatctt catatacaga atttggacca cctgatagaa
     3601 taattcctac aggattgact tcacgaactt cagcagctga aattttatgg ctttttagtt
     3661 ctgaaaaaac accaatctca cggatacggc gtgaaatcag ctggttgtac tggctaccat
     3721 agtccaatac gatgattttt tctacatctt gcaaatcagt tgaaatgttg ctcatctttt
     3781 tcctttctca aaagaaatat cttttctcaa tattctatca caaataaggg cgaattacca
     3841 actaaacaag gcgaagtttg actttttcta gtttattggg gtacaataga gaaaagatag
     3901 aaatgaagtg aaaaatatgc tacctgctta tatgaaaatc catgatcaga taaaaaagga
     3961 tattgacgag caccgttggg ctattggtga gaggcttccc agtgaaagag atttagctga
     4021 gcagtttgcg gtcagtcgca tgaccctccg ccaagccgta tctctattag tcgaagaagg
     4081 cgtcttagag cgccatgtag gaagcggcac ctttgtttcc agtactcgag tacaagaaaa
     4141 gatgcgaggg acaaccagtt ttactgaaat tgtcaaatcc caaggtaaag ttccctctag
     4201 ccagctcatt tcctacaaaa aaaccattcc caatgagcaa gaagttgcca agctaggaat
     4261 ttttccaacg gacaatatta tccgaatgga gcgggtccgc tatgccgacc aagttcccct
     4321 agtttatgaa gttgcttcta ttcctgaaaa attcattaag gactttaaaa aagaagaaat
     4381 caccagtcat ttcttccaaa ccttgcaaaa acatggctat cgtatcggca aatctcaaca
     4441 gaccatctat gctcgccttg ctaaagaaaa gattgcccac tatttggaag ttgaaaaagg
     4501 acatgctatt cttggattga cccaggtttc ctacctagaa gatggtactg cttttgaata
     4561 cgtaaaaagt caatatgtag gcgaacgctt tgaattttat cttgaaaata attagattac
     4621 cacgcaaaaa ctctctgtca cggacaaaga gtctttttta tttttctaag aataaatctt
     4681 tcaaagaaat caaagttaca gcaaacaata tcattgccat accaagaaaa tcaatgggat
     4741 aaaattgttc attcattatt aagaaggcaa agaaaatcgc cgatattggc tcaattgaag
     4801 ccaacaagct tgacttgacc ggtcctatca gactggctcc tttaaggaaa gctgtatagg
     4861 caaagacagt cccgataagg ataatgcctg caaacgcaag gagaaaatca agactagtcg
     4921 ggatatcggt ctgtagaacc cctgtaaaag gaagggcgac caaacctgct atgaccattc
     4981 ccacaccaat gaccaagctg ctcccccact ttttaatcaa ggctatgggt aaaatgatat
     5041 acagagcata agtcaaggca gaaaagagac cccagaacag accagcaggt gtcatggata
     5101 actggtccaa ctgcccatgt gttgcgatca ggaaggttcc tccgatggcg aatatgatgg
     5161 aaactatctc tcccagtgtc ggtgccaccc tatccttgat acagctataa attaaaattc
     5221 cgacaggaca aacatactga agcaccgtcg ctgttcccgc attggtctcc tgaatagcag
     5281 acagataggc gaattggttg agaaaaagac caatcagagc aaaaataaga agagacagca
     5341 aactctttct atcctttaaa aagaccagta ttttatcctt tgcagtagca taagccaaga
     5401 gcatgagaat tccaccagcg attaaaagac gcaagttggt caagaccaga gccgaaattc
     5461 cgtgtgccat taggtattgg ccactcgttc ctgacaaccc ccaagcaata ccagccacaa
     5521 ctgttagtaa agtccctttt aaactatttg acatgtctct ccttactctt ctttgcgaat
     5581 caagttcatc acttgattgc ggtctaatat ccattgagct ctctcgtcct tttcataggt
     5641 acgattcgat aggaaaatag tggcttcttg cttctgacga ttccacatga taaaggtacc
     5701 tgtatagccc gtatggtcta gccaatctcc ttccaaattc catgctaaag aacgttcctt
     5761 gtcatccaaa ggagaaaaat tttgacttaa gtctcttgca aaatcatctg ctaaatagtg
     5821 ttctaaaaag atttgtaaat cctttatagt cgaaaataaa ccagcgctcc cagcatgtct
     5881 acccaggaga cgagccttgg gatcatgcac tatgcctgcc tctacacctc taactgttgg
     5941 aacagcaagc tcaactggcc caaacttggt ttccgtcatt ccccaaggtt tccagacttg
     6001 atcctttaaa atcacatcca aatcttgatt aaaaattctt tccaaaataa agcccaacag
     6061 caaaaaatgg acatccgaat aaagaaaggc tggctgactt cgtctgttga gatgaaacat
     6121 cgcttccttt aattcagggg ctgttaaaag atcacgatta ggaataaaag gatcaaggtc
     6181 tgttgcatga gtcaagagct ggcgaatagt gatgtctgga taatcactct caggtaaaaa
     6241 atctattacc agtctatcaa tatctaattg acctatttcc cacaagaagg tacaaactgt
     6301 gccaacccca acaaccttgc tgacactagc taggtcataa actagtcctg cctcagtctg
     6361 caagccatgc tctgggtcac tctggcctaa atagaactct gtccattgat tgtccttaaa
     6421 atacgcaaaa gaggctccgg gataaattcc tgcctcgatt tgttcttcta tttttttaat
     6481 aatcttggtc cacttcatac ttcttcaaac cacaattcaa cattatttct atctttacaa
     6541 aggaagaatt tttcagactt aggaataaaa tattcagtag actcaaactt ctggcgaaga
     6601 cttgctatgt ctaattcatt gaccaagaac ttgagcatag ataagtccca ggtaaccgta
     6661 ttgtccacag tcaaatcctg cccctgagct ggaataaaat caagggatgc cccaatttca
     6721 gatgattcca agaaactttc gatatcagtt gggagatgta attccataga aatctcaaat
     6781 ttacttaaag aaattgatgc caaatctgtt tgaaattcag gcttttctcc tacttctact
     6841 agacttgctc tgtcatcttc cgcatgaatc aaaatcaaat catcttctgg tgagaaaatt
     6901 tcaaaagcgt agccattttg acctttatat aatcgatgaa tcgaatctgt tttagataag
     6961 attccttcaa tttctaaggg attttccacc ttgacaatca atctagctag tttttttctt
     7021 ccctctacct tacgagtacg catactggga gcttcttcta aaaccagctt ttcaagaccc
     7081 gtttggtcac ctagtgacag aaaggccgat tcttctaaca aggccttcat tccaagggtt
     7141 tcaatataaa atgtttcatt taattttcta t
//
LOCUS       DAVKEV010000072         7103 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVKEV010000072 DAVKEV010000000
VERSION     DAVKEV010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7103
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.072"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(81..248)
                     /locus_tag="VWZ68_001962"
     CDS             complement(81..248)
                     /locus_tag="VWZ68_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372938.1"
                     /translation="MSLIYSSAKKDFLYWNVLIFIMELPNDVKVQFYELRKKVQSFNQ
                     LSKRFGMDVSG"
     gene            complement(415..486)
                     /locus_tag="VWZ68_001963"
     tRNA            complement(415..486)
                     /locus_tag="VWZ68_001963"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(451..453),aa:Arg,seq:cct)
     gene            complement(528..875)
                     /gene="rplS"
                     /locus_tag="VWZ68_001964"
     CDS             complement(528..875)
                     /gene="rplS"
                     /locus_tag="VWZ68_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEU9372939.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(994..1323)
                     /gene="crcB"
                     /locus_tag="VWZ68_001965"
     CDS             complement(994..1323)
                     /gene="crcB"
                     /locus_tag="VWZ68_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU9372940.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(1317..1691)
                     /gene="crcB"
                     /locus_tag="VWZ68_001966"
     CDS             complement(1317..1691)
                     /gene="crcB"
                     /locus_tag="VWZ68_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU9372941.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(1688..1954)
                     /locus_tag="VWZ68_001967"
     CDS             complement(1688..1954)
                     /locus_tag="VWZ68_001967"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEU9372942.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(2070..2513)
                     /locus_tag="VWZ68_001968"
     CDS             complement(2070..2513)
                     /locus_tag="VWZ68_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEU9372943.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSIGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVV"
     gene            2617..3552
                     /locus_tag="VWZ68_001969"
     CDS             2617..3552
                     /locus_tag="VWZ68_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEU9372944.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3606..3890
                     /locus_tag="VWZ68_001970"
     CDS             3606..3890
                     /locus_tag="VWZ68_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEU9372945.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(3947..4165)
                     /locus_tag="VWZ68_001971"
     CDS             complement(3947..4165)
                     /locus_tag="VWZ68_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372946.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETKPTDESGT"
     gene            complement(4162..5192)
                     /locus_tag="VWZ68_001972"
                     /pseudo
     CDS             complement(4162..5192)
                     /locus_tag="VWZ68_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            5534..6880
                     /gene="gdhA"
                     /locus_tag="VWZ68_001973"
     CDS             5534..6880
                     /gene="gdhA"
                     /locus_tag="VWZ68_001973"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEU9372947.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSNLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGVV"
BASE COUNT         2204 a         1480 c         1286 g         2133 t
ORIGIN      
        1 taattcagtg gaatagtaac gattcttccc ttttttaacg ctctctgttc aataacgatc
       61 aattcacctt gtcacatacc ttagccagaa acatccatac caaatctttt tgaaagctga
      121 ttaaagcttt gtactttctt tctaagttca tagaactgaa ccttaacgtc atttggcaat
      181 tccataataa aaataaggac attccaataa aggaagtcct ttttagcact actataaatc
      241 aaagacattt ttatgatcca ttttattcta taatcattga ccaaaatata atttttggtc
      301 aaaatttggt caaaaaaatt aaaaatgcta aattattttt aaaaatgaac ttgagaaaat
      361 tgccttcaaa taaacatttt gaattttctt tgtctttctt tacattacta aaaatgcccc
      421 ctgcaggaat cgaacctgca actactcctt aggagggagt tgttatatcc attgaactaa
      481 gggagctaga taaaaactct gctgaaaagc agagtttttt agtcgaatta acgacggatt
      541 tctttgatac gagctgcttt accttgaaga gcacgcaagt agtacaattt cgcacgacgt
      601 actttaccgt aacgaacaac ttcgattttt tcaacacgtg gagtgtggat tgggaagata
      661 cgctcaacac ctacaccgtt agagatttta cgaactgtgt agttttctga gattccagca
      721 cctttacgtg cgataacaac accttcaaaa atctggatac gttcacggtt accttcgaca
      781 actttcgcgt gtacacgaac agtgtcacca ggacggaatg atgggatatc tgtacgaagt
      841 tgaccttcag tcaagctttg gattaatgga ttcattttat tctcctatct ttgtcaatct
      901 tgaggaaatt tcctcagcgg ataaactgta tttttgtgcg tccatcacac acaagataca
      961 gtctaccaaa ttttcacaaa aaagtaaaga aatttatagc aaaattccta aaaaaatcgc
     1021 aaccaaacca cctatgtaag tcaaagtcag gtaagaataa aagaccttct tatcacttaa
     1081 cagtctttga agttcgtcat tcaaggtcga aaaagttgtt aaaccgccac aaaatcctgt
     1141 tgctagaata gcatatactt ccttagactc tacatgattg tagaatactc caattaaaaa
     1201 acaacctaaa agattagcta tgagcgttcc gagtggcaat ttagaagctt gattgtagcg
     1261 ggaaaagaaa taccgtacga gtgctcccaa gccacaggcg attgcaagat agacgattac
     1321 catttcttcc tccctagaaa ataagctaag agtaggcctc caccgatgct caaaagcaaa
     1381 tacaggacta aactaagata acgccctgta tcaagcagct tcacagtatc aagcattagg
     1441 ctggaaaaag ttgttaaacc tccgcaaaaa cccgtcccca gtgctaaaat caagccctta
     1501 ctagtcccct tatagaccag atagcccttg acaagaaaaa tcaagcagaa aattcccaga
     1561 tagttgacaa agagagtgcc ccaaggaaag tctggactgg ctggtaacca ggtggaaact
     1621 agatatcgga caagtccgcc caacatagca gctagaaaaa ttcctagcgg ataaaattgt
     1681 tcttttttca tttgatattt tgatcctgat aatcacgcga acgtttgagt atgtccgaaa
     1741 aagtcgctac aatagtctcc tgatagcgct tgtcctctac acgactccta accttttcaa
     1801 aaataacttc ttctctctta gtatctaaaa tcggtttacc tgaagctttc ttataagcaa
     1861 ccaccccctc aactaaatgc attcgttctt ctaacagttt gacaatttgg tcatcgattt
     1921 gatcgatttc ttgacgaata atatctaaat ccatacagtc tcctccttta tttgaattat
     1981 tgtatcaaaa agccatcaat taggctagta aaatcccaac tctcgataag aaaaatgcac
     2041 tgattgatta catcagcgca cttttatgct tatactactt tagcaaccaa ttcttctgcg
     2101 aattgttcca agcgttcaat atcttcttcc tcggcagaaa gatcaacttt aacacactct
     2161 gaaccttttt ctgctcctat tgacacaaag acacggtcaa agtcatcaac agccttacag
     2221 aattcatcgt agaaggtatc tcctgagccg accactccgt agattttgcc attcaagttg
     2281 agatctgcta ggtcttcgta gaagtccatc atctcatctg gcaattcacc atcaccataa
     2341 gtataggtcg caacgatagc gatgtctgct tccaagaagt ctgaagcgtc aacagttgta
     2401 cattcatcaa catcaacatc caagcccaag tcacgtaatt tgtctgctac aatatctgca
     2461 atttcttcgg tattaccggt catactggca aatacaattt ttgctaatgc catatcgtcc
     2521 tcctcaattt atctttctcc attatatcac atctttttca ttttaaaaat aaaaattctt
     2581 gtgctacaat gaaatgagaa agaattgagg ttatttatgg agatttgcca acaaatttta
     2641 gaaaaaatta aagaatacga caccattatc attcatcgtc atatgaaacc agaccctgat
     2701 gccttgggaa gtcaggtggg attgaaagcc ttgctggaac atcatttccc agaaaaaacc
     2761 atcaaagccg tcggttttga tgaaccaact cttacttgga tggctgagat ggatcttgtt
     2821 gaagatagag cctaccaagg cgcacttgtc atcgtctgtg atacagctaa tactgctcgt
     2881 atcgatgata agcgctatag tcaaggtgat tttctcatta agattgacca ccatccaaat
     2941 gatgatgtat acggtgacct gtcttgggtc gatactagtt caagtagcgc tagcgagatg
     3001 attaccctat ttgcccaaac aacccaacta gccttggcag atcgcgatgc tgagttgctc
     3061 tttgcaggaa ttgtcggtga tacaggtcgc ttcctctacc cttctaccac tgcacggact
     3121 cttcgcctgg ctgcttattt gagagaacat aactttgact ttgcggctct cactcgcaaa
     3181 atggacacta tgagctacaa aattgctaaa ctgcaaggct acatctacga ccatctggaa
     3241 gtggatgaaa atggtgctgc tcgcgttatc ctgagtcaag aagtcttgaa acaatacaat
     3301 gtaaccgatg ctgaaactgc agccattgtc ggtgcacctg gacgcattga cagagtgagt
     3361 ctctggggaa tttttgtcga acaggctgat ggccactacc gagttcgctt acgcagtaaa
     3421 atccatccta tcaatgaaat cgccaaggag catgatggtg gaggccaccc tctagcaagt
     3481 ggtgctaatt cctatagcct agaagaaaac gaaatcatct accaaaagtt aaaaaacttg
     3541 cttaaaaact gataaaatac ttgccaaact tttcagaatc tgatagacta gtatggtaac
     3601 aatctatggc tcgcaaagag accatggcag aaaggaaata ttgcaaaatg aaaaaagata
     3661 tccatccaga atatcgccca gttgtcttca tggacacaac tactggttac caattcctta
     3721 gcggttcaac aaaacgctct aacgaaacag ttgagttcga aggcgaaact tacccattga
     3781 tccgtgtgga aatttcatca gactcacacc cattctacac tggacgtcaa aagttcactc
     3841 aagcagatgg acgcgtggat cgtttcaaca aaaaatacgg tctcaaataa tgataagaga
     3901 acagtttcgg ctgttctttt ttgtttcttg aaatcaactg ctgttttcat gttccagact
     3961 catctgtagg tttggtttcc atgctactag gcaggaagga aatagctgtt tcaacacgtc
     4021 cataatgagc tgtactattg tcacgaacca cactttcatt gatggtccaa gtggaattca
     4081 ttttcttaaa agcttctcgg actttttcca aatctttgga ggcaatggcc tgctctaagg
     4141 tttcaaaacg aggacttata ctcatctgct ttcacaaagc attctagtcc atctccgatt
     4201 aacgatgggc tttatcacct ccttctccag tccttgtatg atatcttaaa gttgattcat
     4261 gacatcttcc aaagtttgaa aggctttatt tttaaatcca cgtttacgaa tctctttcca
     4321 cacttgttca atggggttca tctctggtgt gtacggagga ataaatgcaa agccaatatt
     4381 agtcggaatc tttaaggtac ttgatttatg ccatatagca ttgtccataa cgagtaaaag
     4441 ataatcatct ggataagctt gtgaaagctc ttctaaaaag gcgttcatcc actcagtatt
     4501 acatccacca gctcttaaga aaaatgattc gcctgtatgg gcatcaacag ctccataaca
     4561 atagcgaaat tctcgtatat agtgactatg gacatgtgga cctactccta ttggagacca
     4621 acaagatccc agtttactga ttctaccgaa accagcctca tcttggtaca tcgagcgaac
     4681 cttatgaaaa ggtctactgg ttttaaagcg ctttcttttc ttcttgaatt gagattttat
     4741 ttttagacgc gacaatggtt tgagcgtctg ctttcttagg atgttctgga cgtggcataa
     4801 tatttcgcca accatggcgc ttcaacagtt gatagaaggc atcacgtgtg taggaacgat
     4861 ataagcctga aataaggtat tgtaacaaat tctcctgcct ctgtagcctt caaatggcgg
     4921 gcaagaaagg ctttctcttc ctcaactgtc atatatgcat ggttacgacc accacgtgtt
     4981 tcttgaagga gagagtcgag tccgaactcc tcatattttt ttacatttcg ccaaatcgtt
     5041 gtttgattac agtctaaaag ctctataatc tctttataag atttgcccat cagacgaaat
     5101 agaacgattt gaaggcgttt atgatattta gctgtacgag agtcttttaa aagtgttttg
     5161 atggcttgga tttcttcttt agttgatttc atatcactat tatataatgc tttttgattt
     5221 tagtctggta taaatattgc tttcctccaa aatggtcata attttactag caaatctaac
     5281 atatcacgga taaattaaca agtgatttct gaattgctaa acattttctt ttcttatagc
     5341 ataccatact ttaagatttt gtctttgaga aagatatttc caagaaaaac gttcgttttt
     5401 ttatctattt tcaaaaaaaa ccaaaaactg aattgaaaga atttttagaa aatttctgtt
     5461 ttttctttac agtgaaaaaa aattctgcta taatgtctta tgtaataaaa tatgacaata
     5521 aaaggagaac gatatgacat ctgctaaaga atatatccaa agcgtgtttg aaactgtaaa
     5581 agctcgtaac gggcacgagg ctgaattcct ccaagctgtt gaagaatttt tcaacacttt
     5641 ggaacctgta tttgaaaaac accctgagta tatcgaagaa aatatcttgg cacgtattac
     5701 tgagcctgag cgcgtgattt ctttccgtgt tccttgggtt gaccgtgatg gaaaagttca
     5761 agtaaaccgc ggctaccgtg ttcaattcaa ctcagctgtt ggaccataca aaggtggact
     5821 tcgtttccac ccaactgtaa accaagggat cttgaaattc ctcggatttg aacaaatctt
     5881 taaaaatgtc ttgactggac ttcctatcgg tggaggtaaa ggtggatcag acttcgatcc
     5941 taaaggtaaa acagatgctg aagtgatgcg cttctgccaa agcttcatga ctgaattgca
     6001 aaaacacatc ggaccatcac ttgacgtacc tgctggtgat atcggtgttg gtggacgtga
     6061 aattggttac ctttacggtc aatacaaacg tcttaaccaa tttgatgctg gtgtcttgac
     6121 tggtaaacct cttggatttg gtggtagctt gattcgtcca gaagcaactg gttacggttt
     6181 ggtttactat actgaagaaa tgctcaaagc taacggtaac agctttgctg gtaagaaagt
     6241 cgttatttca ggttctggta acgttgctca atacgctctt caaaaagcaa ccgaacttgg
     6301 tgcaacagtt atctctgttt ctgactcaaa cggctatgtt atcgatgaaa acggtatcga
     6361 cttcgatctt ttggttgatg ttaaagaaaa acgtcgcgct cgtttgactg agtatgcagc
     6421 tgagaaagca actgctactt atcatgaagg ttctgtatgg acttacgctg gaaactatga
     6481 cattgcgctt ccatgtgcta ctcaaaacga aatcaacggt gaagcagcta aacgtttggt
     6541 tgctcaaggc gttatctgtg tatctgaagg tgccaacatg ccaagcaacc ttgatgccat
     6601 caaagtttac aaagaaaatg gtatcttcta cggacctgcc aaagctgcca acgctggtgg
     6661 tgtagccgtt tcagcccttg aaatgagcca aaacagcctt cgcctctcat ggactcgtga
     6721 agaagttgat ggacgtctca aagacatcat gaccaacatc tttaacacag ctaaaacaac
     6781 ttcagaaaca tatggtcttg ataaagacta ccttgcagga gctaacattg ctgcctttga
     6841 aaatgtagca aacgctatga ttgcacaagg cgtggtataa aaaaaaatta cggaaactga
     6901 ctacccagac gggtagccag ttttttcaat tcctaaaatt taagattcta atacccttta
     6961 tgcaaaaata tagaattcta cctttttctt tatataggct aatgttttta atatatttat
     7021 tgtctatttt tgaaaagaca ataaaactat tctactatag attatcattt cccacaattc
     7081 ataactcaaa cctaatattt tgt
//
LOCUS       DAVKEV010000073         6842 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVKEV010000073 DAVKEV010000000
VERSION     DAVKEV010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6842
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.073"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            94..6513
                     /locus_tag="VWZ68_001974"
     CDS             94..6513
                     /locus_tag="VWZ68_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU9372948.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     AENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKEENSNK
                     SQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGSKAIKELSSLKNTKVLYTYDRIF
                     NGGAIETTQDNLNKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFG
                     KNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAF
                     NYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSY
                     KMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAG
                     IPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFD
                     KVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKI
                     AVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQV
                     FSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKE
                     IDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKST
                     YGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTAR
                     PMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLK
                     EIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVP
                     EIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEME
                     ALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIP
                     GTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSGSKIA
                     NIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHF
                     IRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQ
                     FEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTY
                     HKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQ
                     GRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKGMISY
                     YLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKEKSSF
                     TIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAYEDES
                     ALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEIKATK
                     YDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDDRIKAETKIRMPEKNKETKAEY
                     PYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKV
                     TTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLM
                     SALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEA
                     IKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVN
                     ESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYL
                     QTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFD
                     GEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSE
                     LKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYV
                     INLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDH
                     SQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLG
                     LKKKNQD"
BASE COUNT         2709 a          920 c         1327 g         1886 t
ORIGIN      
        1 tagataatac ttagtaaaac tttttataac aaaggctagc aaagttaaag tttattatct
       61 attggaagtt atataaatat gtaaggaatt aaaatgaaaa aaagtacagt attgtcatta
      121 accacagctg cagttatttt agcagcctat gcccctaatg aggtagtctt agcagacaca
      181 tctagctctg aagatgcttt aagcatctct gataaagaaa aagtagcaga aaataaagag
      241 aaacataaag atattcataa tgctatagaa acttcaaagg atactgaaga aaagaaaaca
      301 acaattattg aggaaaaaga agttgttagt aaaaatcctg tgatagacac taaaactagc
      361 aatgaagaag caaaaatcaa agaagaaaat tccaataaat cccaaggaga tcatacggac
      421 tcatttgtga ataaaaacac agaaaatccc aaaaaagaag ataaagttgt ctatattgct
      481 gaatttaaag ataaggaatc tggatcaaaa gcaatcaagg aactatccag tcttaagaat
      541 acaaaagttt tatatactta tgatagaatt tttaacggtg gtgctattga aacaactcaa
      601 gataatctga ataaaattaa acaaatagaa ggtattacat cggttgaaag ggcacaaaaa
      661 gtccaaccca tgatgaatca tgccagaaag gaaattggag ttgaggaagc tattgattac
      721 ctaaagtcta tcaatgctcc gtttgggaaa aattttgatg gtagaggtat ggtcatttca
      781 aatatcgata ctggaacaga ttataggcat aaggctatga gaatcgatga tgatgccaaa
      841 gcctcaatga gatttaaaaa agaagactta aaaggaactg ataaaaatta ttggttgagt
      901 gataaaatcc ctcatgcgtt caattattat aatggtggca aaatcactgt agaaaaatat
      961 gatgatggaa gggattattt tgacccacat gggatgcata ttgcagggat tcttgctgga
     1021 aatgatactg aacaagatat caaaaacttt aacggcatag atggaattgc acctaatgca
     1081 caaattttct cttacaaaat gtattctgac gcaggatctg ggtttgcggg tgatgaaaca
     1141 atgtttcatg ctattgaaga ttctatcaaa cacaacgttg atgttgtttc ggtatcatct
     1201 ggttttacag gaacaggtct tgtaggtgag aaatattggc aagctattag ggcattaaga
     1261 aaagcaggca ttccaatggt tgtcgctacg ggtaactatg cgacttctgc ttcaagttct
     1321 tcatgggatt tagtagcaaa taatcatctg aaaatgaccg acactggaaa tgtaacacga
     1381 actgcagcac atgaagatgc gatagcggtc gcttctgcta aaaatcaaac agttgagttt
     1441 gataaagtta acataggtgg agaaagtttt aaatacagaa atataggggc ctttttcgat
     1501 aagaataaaa tcacaacaaa tgaagatgga acaaaagctc ctagtaaatt aaaatttgta
     1561 tatataggca aggggcaaga ccaagatttg ataggtttgg atcttagggg caaaattgca
     1621 gtaatggata gaatttatac aaaggattta aaaaatgctt ttaaaaaagc tatggataag
     1681 ggtgcacgcg ccattatggt tgtaaatact gtaaattact acaatagaga taattggaca
     1741 gagcttccag ctatgggata tgaagcggat gaaggtacta aaagtcaagt gttttcaatt
     1801 tcaggagatg atggtgtaaa gctatggaac atgattaatc ctaataaaaa aactgaagtc
     1861 aaaagaaata ataaagaaga ttttaaagat aaattggagc aatactatcc aattgatatg
     1921 gaaagtttta attccaacaa accgaatgta ggtgacgaaa aagagattga ctttaagttt
     1981 gcacctgaca cagacaaaga actttataaa gaagatatca tcgttccagc aggatctaca
     2041 tcttgggggc caagaataga tttactttta aaacccgatg tttcagcacc tggtaaaaat
     2101 attaaatcca cgcttaatgt tattaatggc aaatcaactt atggctatat gtcaggaact
     2161 agtatggcga ctccaatcgt ggcagcttct actgttttga ttagacctaa attaaaggaa
     2221 atgcttgaaa gacctgtatt gaaaaatctt aagggagatg acaaaataga tcttacaagt
     2281 cttacaaaaa ttgccctaca aaatactgcg cgacctatga tggatgcaac ttcttggaaa
     2341 gaaaaaagtc aatactttgc atcacctaga caacagggag caggcctaat taatgtggcc
     2401 aatgctttga gaaatgaagt tgtagcaact ttcaaaaaca ctgattctaa aggtttggta
     2461 aactcatatg gttccatttc tcttaaagaa ataaaaggtg ataaaaaata ctttacaatc
     2521 aagcttcaca atacatcaaa cagacctttg acttttaaag tttcagcatc agcgataact
     2581 acagattctc taactgacag attaaaactt gatgaaacat ataaagatga aaaatctcca
     2641 gatggtaagc aaattgttcc agaaattcac ccagaaaaag tcaaaggagc aaatatcaca
     2701 tttgagcatg atactttcac tataggcgca aattctagct ttgatttgaa tgcggttata
     2761 aatgttggag aggccaaaaa caaaaataaa tttgtagaat catttattca ttttgagtca
     2821 gtggaagaaa tggaagctct aaactccaac gggaagaaaa taaacttcca accttctttg
     2881 tcgatgcctc taatgggatt tgctgggaat tggaaccacg aaccaatcct tgataaatgg
     2941 gcttgggaag aagggtcaag atcaaaaaca ctgggaggtt atgatgatga tggtaaaccg
     3001 aaaattccag gaaccttaaa taagggaatt ggtggagaac atggtataga taaatttaat
     3061 ccagcaggag ttatacaaaa tagaaaagat aaaaatacaa catccctgga tcaaaatcca
     3121 gaattatttg ctttcaataa ccaagggatc aacgctccat catcaagtgg ttctaagatt
     3181 gctaacattt atcctttaga ttcaaatgga aatcctcaag atgctcaact tgaaagagga
     3241 ttaacacctt ctccacttgt attaagaagt gcagaagaag gattgatttc aatagtaaat
     3301 acaaataaag agggagaaaa tcaaagagac ttaaaagtca tttcgagaga acactttatt
     3361 agaggaattt taaattctaa aagcaatgat gcaaagggaa tcaaatcatc taaactaaaa
     3421 gtttggggtg acttgaagtg ggatggactc atctataatc ctagaggtag agaagaaaat
     3481 gcaccagaaa gtaaggataa tcaagatcct gctactaaga taagaggtca atttgaaccg
     3541 attgcagaag gtcaatattt ctataaattt aaatatagat taactaaaga ttacccatgg
     3601 caggtttcct atattcctgt aaaaattgat aacaccgccc ctaagattgt ttcggttgat
     3661 ttttcaaatc ctgaaaaaat taagttgatt acaaaggata cttatcataa ggtaaaagat
     3721 cagtataaga atgaaacgct atttgcgaga gatcaaaaag aacatcctga aaaatttgac
     3781 gagattgcga acgaagtttg gtatgctggc gccgctcttg ttaatgaaga tggagaggtt
     3841 gaaaaaaatc ttgaagtaac ttacgcaggt gagggtcaag gaagaaatag aaaacttgac
     3901 aaagacggaa ataccattta tgaaattaaa ggtgcgggag atttaagggg aaaaatcatt
     3961 gaagtcattg cattagatgg ttctagcaat ttcacaaaga ttcatagaat taaatttgct
     4021 aatcaggctg atgaaaaggg gatgatttcc tattatctag tagatcctga tcaagattca
     4081 tctaaatatc aaaagcttgg cgagattgca gaatctaaat ttaaaaattt aggaaatgga
     4141 aaagagggta gtctaaaaaa agatacaact ggggtagaac atcatcatca agaaaatgaa
     4201 gagtctatta aagaaaaatc tagttttact attgatagaa atatttcaac aattagagac
     4261 tttgaaaata aagacctaaa gaaactcatt aaaaagaaat ataaggaaga agacgacttt
     4321 gtaactggtg gaaaaagaac agtagaactt gattataaat atgacgataa aggaaatata
     4381 actgcctatg aagatgaaag tgctctagaa tatgaaactg aaaaatttga cgaaataaaa
     4441 tcaaaaattt atggtgttct aagcccatct aaagatggac actttgaaat tcttggaaag
     4501 ataagcaatg tttctaaaaa tgccaaggta tattatggaa ataactataa atttatagaa
     4561 atcaaagcga ctaagtatga ctcacattca aaaacgatga catttgattt atacgctaat
     4621 attaatgata ttgtggatgg attagctttt gctggagata tgcggttttt tgttaaagat
     4681 gatgatcgaa taaaagctga aactaaaatt agaatgcctg aaaaaaataa ggaaactaaa
     4741 gcagaatatc cctatgtatc aagttatggg aatgtaatcg aattaggaga aggagatctt
     4801 tcaaagaaca aaccagacaa tttaactaaa atggaatctg gtaaaatcta ttctgattca
     4861 gaaaaacaac aatatctgtt aaaggataac atcattctaa gaaaaggcta tgcactaaaa
     4921 gtgactacct ataatcctgg aaaaacggat atgttagaag ggaatggagt ctatagcaag
     4981 gaagatatag caaaaataca aaaggccaat cctaatctaa gagtcctttc agaaacaaca
     5041 atttatgctg atagtagaaa tgttgaagat ggaagaagta cccaagctgt attaatgtcg
     5101 gctttggacg gctttaacat tataaggtat caagtgttta catttaaaat gaacgataaa
     5161 ggggaagcta tcgataaaga cggaaatctt gtgacagatt cttctaaact tgtattattt
     5221 ggtaaggatg ataaagaata cactggagag gataagtcca atgtagaagc tataaaagaa
     5281 gatggctcca tgttatttat tgataccaaa ccagtaaacc tttcaatgga taagaactac
     5341 tttaatccat ctaaatctaa taaaatttat gtacgaaatc cagaatttta tttaagaggt
     5401 aagatttctg ataagggtgg ttttaactgg gaattgagag ttaatgaatc ggttgtagat
     5461 aattatttaa tctacggaga tttacacatt gataacacta gagattttaa tattaagttg
     5521 aatgttaaag acggtgacat catggactgg ggaatgaaag actataaagc aaacggattt
     5581 ccagataagg taacagatat ggatggaaat gtttatcttc aaactggcta tagcgatttg
     5641 aatgctaaag cagttggagt ccactatcag tttttatatg ataatgttaa acccgaagta
     5701 aacattgatc ctaagggaaa tactagtatc gaatatgctg atggaaaatc tgtagtcttt
     5761 aacatcaatg ataaaagaaa taatggattc gatggtgaga ttcaagaaca acatatttat
     5821 gtaaatggaa aagaatatac atcatttgat gatattaaac aaataacaga caagacacta
     5881 aacattaaga ttgttgtaaa agattttgca agaaatacaa ccgtaaaaga attcatttta
     5941 aataaagata cgggagaggt aagtgaatta aaacctcata gggtaactgt gaccattcaa
     6001 aatggaaaag aaatgagttc aacgatagtg tcggaagaag attttatttt acctgtttat
     6061 aagggtgaat tagaaaaagg ataccaattt gatggttggg aaatttctgg tttcgaaggt
     6121 aaaaaagacg ctggctatgt tattaatcta tcaaaagata cctttataaa acctgtattc
     6181 aagaaaatag aggagaaaaa ggaggaagaa aataaaccta cttttgatgt atcgaaaaag
     6241 aaagataacc cacaagtaaa ccatagtcaa ttaaatgaaa gtcacagaaa agaggattta
     6301 caaagagaag atcattcaca aaaatctgat tcaactaagg atgttacagc tacagttctt
     6361 gataaaaaca atatcagtag taaatcaact actaacaatc ctaataagtt gccaaaaact
     6421 ggaacagcaa gcggagccca gacactatta gctgccggaa taatgtttat agtaggaatt
     6481 tttcttggat tgaagaaaaa aaatcaagat taagataaaa gctatagaaa aaaatggttt
     6541 atgtactgag attagatagt gaggtgatga catagttttg tgaaaacagc catttataac
     6601 tcaattattt agtttacttc actattgata ctatttggag ttattaatgg acttagttta
     6661 gataactaat gaattgattg aaagggttag tattgacaat attggtcata ttgattagaa
     6721 aatagagtct atcaaaattt aaaggctaat agaggtgatg agacaatttc ggctctttgt
     6781 caactgtagt gggttgaagt cagctaagct cgagaaagga caaattttgt cctttctttt
     6841 tt
//
LOCUS       DAVKEV010000074         6726 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVKEV010000074 DAVKEV010000000
VERSION     DAVKEV010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6726
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.074"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..334
                     /locus_tag="VWZ68_001975"
                     /pseudo
     CDS             1..334
                     /locus_tag="VWZ68_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            501..701
                     /locus_tag="VWZ68_001976"
     CDS             501..701
                     /locus_tag="VWZ68_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372949.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            726..1142
                     /locus_tag="VWZ68_001977"
     CDS             726..1142
                     /locus_tag="VWZ68_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372950.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLDVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1373..2080
                     /gene="ccdA2"
                     /locus_tag="VWZ68_001978"
     CDS             1373..2080
                     /gene="ccdA2"
                     /locus_tag="VWZ68_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU9372951.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2091..2648
                     /gene="sdbB"
                     /locus_tag="VWZ68_001979"
     CDS             2091..2648
                     /gene="sdbB"
                     /locus_tag="VWZ68_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEU9372952.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2769..4160
                     /locus_tag="VWZ68_001980"
     CDS             2769..4160
                     /locus_tag="VWZ68_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEU9372953.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAEMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4303..5220
                     /gene="adcAII"
                     /locus_tag="VWZ68_001981"
     CDS             4303..5220
                     /gene="adcAII"
                     /locus_tag="VWZ68_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEU9372954.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5228..>6726
                     /locus_tag="VWZ68_001982"
     CDS             5228..>6726
                     /locus_tag="VWZ68_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU9372955.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITYRTVNGVAVPHGDHYHFIPYSQLSPLEEKLA
                     RMIAVKGQNGAVLPGMHYLKPAPKPQVQPSTEKKQTDFAVEQVVRKVGEGYVVEIAGV
                     SHYVFAKDLAKDKIDAIENLLSKKTQETHALVAKKENVAPRDQEFYDKAYNLLTQAHK
                     VLSENKGRTSDFQALDKLAERLNNESSNKVKLVDDLLAFLAPITHPERLG"
BASE COUNT         2080 a         1217 c         1410 g         2019 t
ORIGIN      
        1 aaccacacct actatgaaca agacccagaa aaagtagcct tatttcttaa gaattttaat
       61 agtttaaagc acctagcacc tgtttagatt gacgaaacag gattcgatac ttatttttat
      121 cgagaatatg gtcgctcatt aaaaggtcag ttaagaagag gcaaagtatc tggaagaaga
      181 tatcagagaa tttctttggt tgcaggtcta acaaatgaat ggtgagttaa tcgctccaat
      241 gacttacgaa gagacgatga cgagcgactt ttttgaagta tggtttcaga aatttctctt
      301 accaacatta accacaccat cggttattat agtaaaatgg aataagaaca ggacaaatcg
      361 atcaggacag taaaatcgaa ttctaacaat gttttagaag tctatatgta ctattctagt
      421 ttcaatatac cataactgct cctagtcaac ctgcaagtcc tgtcccagct ccaagctcag
      481 ctccgactca agatcctaga gtggtagcaa gcgcttcggc tagctcaacg agcacacaag
      541 ctcaagagca agttgacaag tctgaacttc gtgccttgag tcaagagtta gaccaacgct
      601 tgaaagcttt ggcaacagta tctgatccaa aaatcgatgc aaccaaggct gtcctcctag
      661 atgctcaaaa agctccggaa gatagtgcct tgacagagta aggtctgcat actgcagtag
      721 agtctgtgaa ggctgccttg gactctctca aagatgtgaa agcaaatgct agcgacagca
      781 agcctgcaca ggacaagaag gatgcaaaac aaggaacgga agatagtaag gattcagata
      841 agatgactga aacaaactca gttccggcag gagtgattgt ggtcagtcta cttgccctcc
      901 tagacgtgat tgccttctgg ctgattcgcc gtaagaaaga gtcagaaatc cagcaattaa
      961 gcacggaatt gatcaaggtt ctaggacagc tagatgcaga aaaagcggat aaaaaagtcc
     1021 ttgccaaagc ccaaaacctt ctccaagaaa cccttgattt cgtgaaagaa gaaaatggct
     1081 cagcagagac agaaactaaa ctagtagagg agcttaaagc aatccttgac aaactcaagt
     1141 aaaacatgat ttatgaaatg tcagacctaa aagacatttt cgttcacaaa agcagtgacg
     1201 agtaatcctt gtcgttgctt tttggctatt ttgggggata agatccgcct tgactagcaa
     1261 aagaaaagat tggtccaata gtgcccgata cgattttgcg tagcagaaag cttacaaata
     1321 aaattgaata tagtaaaata ggattagaat tattaagaaa gttggttctt tattggaaac
     1381 gatagtattt ttaatctctg tttttctagc aggtgtttta tccttttttt ctccttgtat
     1441 ttttcctctt ctgccagtct atgctgggat tttattggat gatcaagaaa gtgcaaaaag
     1501 cttttctttg tttgggagaa aggttctctg gtcaggcttg attcgaacac tttgctttat
     1561 cgctggtatc tctctcattt tctttattct aggctttggt gctggttact ttggtcatat
     1621 tctctatgca aattggtttc gatatgtcat gggagctatt attatcattt tgggtcttca
     1681 ccagatggaa atttttcatt tgaagaaatt agaagttcaa aaaagtttta cctttaaaaa
     1741 atcagattct aatcgttatt ggtcagcttt tttacttggt attaccttta gctttggttg
     1801 gacaccttgt attggtccag ttttaagttc tgttttagca cttgcggctt ctggaggcaa
     1861 tggtgcttgg caaggagcga tttatactct catttacact ctgggcatgg cccttccttt
     1921 cttggtcttg gcactagctt caggtctagt catgccatat tttagtaaaa tcaagcgtca
     1981 tatgatgcta ctaaagaaaa ttggtggttt cctcattgtt ttaatgggaa ttttgttact
     2041 attaggacaa gtaaatgttc tagctggaat ttttgaataa aggaggacaa atgaaaaaag
     2101 taatgtttgc tggcttaagt ctcttgtcat tagttgtatt gatggcctgt ggtgaggaag
     2161 aaactaaaaa gactcaagca gcacaacagc caaaacaaca aacgactgta caacaaattg
     2221 ctgttggaaa agatgctcca gacttcacat tgcaatccat ggatggcaaa gaagttaagt
     2281 tatctgattt taagggtaaa aaggtttact tgaagttttg ggcttcatgg tgtggtccat
     2341 gcaagaaaag tatgccagag ttgatggaac tagcggcgaa accagatcgt gatttcgaaa
     2401 ttcttactgt cattgcacca ggaattcaag gtgaaaaaac tgttgagcaa ttcccacaat
     2461 ggttccagga acaaggatat aaggatatcc cagttcttta tgataccaaa gcaaccacct
     2521 tccaagctta tcaaattcga agcattccta cagaatattt aattgatagc caaggaaaga
     2581 ttggaaagat tcaatttggt gctatcagta atgcggatgc agaagcagca tttaaagaaa
     2641 tgaactagaa tcgataaaat ctgattacaa gatgtagtca gattttttta gaaaaacatt
     2701 ttataaatat tcacatatct cctatattta tggtaaaata gaattatcag tttattttgg
     2761 agtcaaagat gaatatattt agaacaaaga atgttagttt agataaaaca gagatgcata
     2821 ggcatttgaa gttatgggat ttgattttgc tgggtatcgg agccatggta gggacaggcg
     2881 tctttacaat cacaggtact gcagctgcaa cacttgctgg cccagcccta gtgatttcaa
     2941 tcgttatttc tgccttgtgt gtgggattat cagccctctt ttttgcagaa tttgcctcgc
     3001 gagtacccgc tacaggaggt gcctatagtt acctctatgc tatcttagga gaattccctg
     3061 cctggttggc tggttggtta accatgatgg agttcatgac agccatatca ggcgtagctt
     3121 cgggttgggc agcttatttt aaaggcttgc tctctcaata cgggatagcc tttcctcagg
     3181 ctttaaatgg tacctttaat cctcaagcag ggacatttgt tgatttattg cctattcttg
     3241 tcttggtctt ggtgacttcg cttgttttac taaatgccaa ggcagcctta cgctttaatt
     3301 cgattctagt tattttgaaa ttttccgctt tagctctctt tgttttagta ggaatttgga
     3361 atattaagtt tgataattgg agcaattttg ctccttacgg ttttggacaa atctatggag
     3421 ctagcactgg tattatggct ggtgcgtcct tgatgttctt cggttttttg ggatttgaat
     3481 ccatctctat ggctgtagat gaagtcaaga ctcctcaaaa aaatattcct agagggattg
     3541 tcttatcgct ttctatcgta accattctct atgccttggt gacccttgtt ttgactggtg
     3601 tggttcacta tagtcattta aatgtcgatg atgccgttgc ctttgccctt cgtagtgttg
     3661 ggattagttg ggcagccaac tatgtgtcat tagtggctat cttgaccttg attacagttt
     3721 gtatttcgat gacctatgcc ctatcgcgta tgatttacag tttagcacgt gacggcttag
     3781 tgcctgctgc ctttaaggaa ctgacgaaga ctagcaagat accaaagaat gctactatct
     3841 tgacaggtct agcttcagca gtagcagcag aaatgttccc actagccagt attgcagcct
     3901 ttttaaatat ttgtacctta gcctacttga tcatgctggc ttatggtctg attcgcttac
     3961 ggaaagaaaa aggaatgccc aaagctgggg aatttaaaac accattggta cctctgttac
     4021 caattttatc gatcatcatt tgtttatcct tcatgttaca gtataatatg aacacctgga
     4081 ttgctttcct agttgcgttg ttagtaggaa gtattattta cttcacttat ggctataagc
     4141 attctaccat agaagaataa agtgaaagtc tattgagttg ttgacactca gtagattttt
     4201 atatgtgaaa gaaatttcaa attttttcta aaaatatctt gacagattaa attttcagga
     4261 gtagaatatt tactagttaa ttaaatggtt aaggagttgt tcatgaagaa acaaaattta
     4321 tttttagtcc tgttaagtgt ctttcttttg tgtttggggg cttgtggtca aaaggaaagt
     4381 cagacaggaa aggggatgaa aattgtgacc agtttttatc ctatctacgc tatggttaag
     4441 gaagtatctg gtgacttgaa tgatgttcgg atgattcagt caagtagtgg gattcactcc
     4501 tttgaacctt cggcaaatga tatcgcagcc atctatgatg cagatgtctt tgtttaccat
     4561 tctcatacac tcgaatcttg ggcaggaagt ctggatccaa atctaaaaaa atccaaagtg
     4621 aaggtcttag aggcttctga gggaatgacc ttggaacgtg tccctggact agaggatgtg
     4681 gaagcagggg atggagttga tgaaaaaacg ctctatgacc ctcacacatg gctagatcct
     4741 gaaaaagctg gagaagaagc ccaaattatc gctgataaac tttcagaggt ggatagtgag
     4801 cataaagaga cttatcaaaa aaatgcgcaa gcctttatca aaaaagctca ggaattgact
     4861 aagaaattcc aaccaaaatt tgaaaaagcg actcagaaaa catttgtaac acaacataca
     4921 gccttttctt atctagcgaa gagatttggg cttaatcaac ttggtattgc aggtatctct
     4981 cctgaacaag aaccaagtcc acgacaacta acagaaattc aggaatttgt taagacctat
     5041 aaggttaaaa cgatttttac agaaagtaac gcttcttcaa aagtagctga aactcttgtc
     5101 aaatcaacag gtgtgggtct taaaactctg aatcctttag agtcagaccc acaaaatgac
     5161 aagacctatt tagaaaatct tgaagaaaat atgagtattc tagcagaaga attaaagtga
     5221 ggaaagaatg aaaatcaata aaaaatatct agcaggttca gtggcagtcc ttgccctaag
     5281 tgtttgttcc tatgaacttg gtcgtcacca agctggtcag gttaagaaag agtctaatcg
     5341 agtttcttat atagatggtg atcaggctgg tcaaaaggca gaaaatttga caccagatga
     5401 agtcagtaag agagagggga tcaacgccga acaaattgtt atcaagatta cggatcaagg
     5461 ttatgtgacc tctcatggag accattatca ttactataat ggcaaggttc cttatgatgc
     5521 catcatcagt gaagaacttc tcatgaaaga tccgaattat cagttgaagg attcagacat
     5581 tgtcaatgaa atcaagggtg gctatgtgat taaggtagac ggaaaatact atgtttacct
     5641 taaagatgca gcccatgcgg acaatattcg gacaaaagaa gagattaaac gtcagaagca
     5701 ggaacgcagt cataatcaca actcaagagc agataatgct gttgctgcag ccagagccca
     5761 aggacgttat acaacggatg atgggtatat cttcaatgca tctgatatca ttgaggacac
     5821 gggtgatgct tatattgtcc ctcacggcaa tcacttccac tatattccta agagtgattt
     5881 gtctgccagt gaattagctg ctgcccaagc ctattggaat gggaagcagg gatctcgtcc
     5941 ttcttcaagt tctagtcata atgcaaatcc agctcaacca agattgtcag agaaccacaa
     6001 tctgactgtc actccaactt atcatcaaaa tcaaggggaa aacatttcaa gccttttacg
     6061 tgaattgtat gctaaaccct tatcagaacg ccatgtagaa tctgatggcc tagtatttga
     6121 tccggcacaa ataacatatc gtacagtcaa tggtgttgct gtaccgcacg gagaccatta
     6181 tcactttatt ccttattcac aactgtcacc tttggaagaa aaattggctc gtatgattgc
     6241 tgttaaggga caaaatggtg cagtcttgcc aggaatgcat tatttgaaac cagcaccaaa
     6301 accgcaagtt caaccatcaa ctgagaaaaa acaaactgat tttgcagtag aacaggttgt
     6361 tagaaaagtt ggagaaggct atgttgtgga aattgctggt gtcagtcact atgtttttgc
     6421 taaagacttg gctaaggata agattgatgc tattgaaaat ctcttgtcta agaaaactca
     6481 agagacacat gctctagttg ctaaaaaaga aaatgtcgct cctcgtgacc aagaatttta
     6541 tgataaagct tacaatctgt taacccaggc tcataaagtc ttgtctgaaa ataaaggtcg
     6601 tacttctgat ttccaagcct tagacaaatt agcagaacgc ttgaataatg aatcttctaa
     6661 taaagtaaaa ttggtagatg atttattggc attcctagca ccaattaccc acccagaacg
     6721 ccttgg
//
LOCUS       DAVKEV010000075         6654 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVKEV010000075 DAVKEV010000000
VERSION     DAVKEV010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6654
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.075"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..524
                     /locus_tag="VWZ68_001983"
                     /pseudo
     CDS             1..524
                     /locus_tag="VWZ68_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822207.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            452..904
                     /locus_tag="VWZ68_001984"
     CDS             452..904
                     /locus_tag="VWZ68_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372956.1"
                     /translation="MEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYSDYS
                     KDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQVVIM
                     ESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            1723..2082
                     /locus_tag="VWZ68_001985"
     CDS             1723..2082
                     /locus_tag="VWZ68_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372957.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIAE
                     VNQVQSLSRGFREKYMR"
     gene            2092..2457
                     /locus_tag="VWZ68_001986"
     CDS             2092..2457
                     /locus_tag="VWZ68_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEU9372958.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSRLISQEQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSH"
     gene            2444..4294
                     /locus_tag="VWZ68_001987"
     CDS             2444..4294
                     /locus_tag="VWZ68_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEU9372959.1"
                     /translation="MVVTKHFATHGKKYRRRLIKYILNPDKTDNLKLVSDFGMSNYLD
                     FPSYEEMVEMYNVNFTNNDKLYEYRNDRQEKHQQNIHAHHLIQSFSPEDNLTPEEINR
                     IGYETIMELTGGRFRFIVATHTDKDHIHNHILINAIDCNSDKKLIWNYALERNLRMIS
                     DRISKMAGAKIIEKRFSYRDYQKYRATSHKFELKQRLYFLMQQSKSFDDFLEKAEQLH
                     VHIDFSQKHSRFMMTDRAMTKPIRGRQLSKRDLYDEDFFRMHFTKQEIASRLEFLLNC
                     VNSLEGLLTKSKELNLTIDLKQKNVIFILEENGKQFSLSHKKISDEKLYDVNFFQDYF
                     KNKEVGVSEGIENLQAQYRAFQEERDKEKVSTEEIEEAFETFKEKRDAVHEFEVKLTE
                     HQIEKLVDEGIYIKVSFGINQSGLIFIPNYQLDIMEEENQKKYKVYIRETTSYFVYNK
                     EHSDKNQYIKGRTLIRQLTNDSRVIPYRRPTVERLQEKISEISLLIELTETDKKYQDI
                     KDNLVSEIAELDIKLTQTNEKIATLNKMAEVLINSKSEGSGSQKLARHEFSKLNMTES
                     TTLEQVNEELLKLQQEFGNVLDEYEKTIRKLGQLFKVFDECINKEIMNEI"
     gene            4550..5982
                     /locus_tag="VWZ68_001988"
                     /pseudo
     CDS             4550..5982
                     /locus_tag="VWZ68_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886556.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(6220..6354)
                     /locus_tag="VWZ68_001989"
                     /pseudo
     CDS             complement(6220..6354)
                     /locus_tag="VWZ68_001989"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT         2318 a         1055 c         1302 g         1979 t
ORIGIN      
        1 ttctagttca aaagaatata ttagttttct tatgttagca gaggcaatca taaaaaatgg
       61 aatagaaata gttgtagtaa ctgatcataa tactaccaaa ggtattaaaa agttacaaat
      121 ggcagtctca atcataatga aaaattatcc gatttatgat atacatcctc atattttaca
      181 tggagtagaa attagtgcag cagataaatt gcatattgta tgtatatatg attatgaaca
      241 agaatcatgg gttaatcaat ggttaagtga aaatattata agtgagaaag atggaagtta
      301 tcaacattca ctgactataa tgaaggattt caataatcaa aaaatagtta actatattgc
      361 tcatttcaat agttatgaca ttttgaaaaa aggttctcac ttatcaggtg catataaacg
      421 aaaaattttt tctaaagaaa atacacgatt tttggagttt aatattaact cgaaagaatc
      481 ttcgcaacaa cttgatattc tctataaaga agttggtgta ttaagtttgg gacaaaaagt
      541 tgtagccatg cttgattttt tattagcata tagtgactat tctaaagact tcagaccatt
      601 gattattgat cagcctgaag acaatctaga caatcgttat atttacaggc atttagttca
      661 gcagtttaga gatgtgaaag ctcaacgtca aattatttta gcaacacata atgctacaat
      721 tgtaacaaat tctatgacag atcaagttgt tattatggag tcagatggag ttaacggatg
      781 gattgaatca cagggatatg ttagtgaaaa atatataaaa aatcatatca tcaatcaatt
      841 agagggagga aaagattcct tcaagcataa aatgtctata tatgagacgg ctttatcaga
      901 gtagagtcag aaaaagtagg ttagaaattt agcctacttt tttctttgtt cgacaggcat
      961 agtgtacatc tgaggtccaa gtcctctgtg gatatttgct gcagatgaaa ccaatagcga
     1021 ctcctaagcc tgaatatcgt gaggtagggg ggataggaag gaattagcga aatcaaggtt
     1081 ctacaaacag aatcgtgact tgaagccata tatagcggat gaggaactct aaaatccaaa
     1141 taggtgtcgt aacctatata cgtaaattac gagagtaaac taggaaagat gtacggctta
     1201 ttccgtgagc gtttaggacg tagtacaacg aatcatggga gtcagctgaa cacatagtat
     1261 tgaagaaatt tctgtaatgg aaatggagcg aagaagtgaa caattaaatg aatacctctc
     1321 taattaaatt tgtcaattct aattcctggt atgaaaagac agtgacctaa aaatgtaaac
     1381 gatgggagct gatcataaat ataggacggt acatgcagtg gtgttagaga ttagtcccta
     1441 cttgatttgt gataacttcc ccaactttct tctgctatac ttttctcaac ttttaaaaat
     1501 ccaactaaga attttacctg ggagtttggg ggcgtagcca ccaagttatc ttatggttag
     1561 ctgtcaaaac tggaaggttt tggttagctg gcgatatgat tttttgggta ttgtgaccac
     1621 aatgcctgag ctcgcaaaga ccgaacaagg actttaagaa atttcccgta tgacacacgg
     1681 ggtcggggtt tacccgagaa aggatgaaag tgaggaaaag agatgtctga acagtaccgt
     1741 gacattcgaa aagaggtaaa tctaaccgca gatgagctaa aacagattga aaaaatgatg
     1801 gaggttgata attatcgtca cttttcacca ttcgtcaggg ataaaatttt gatgactgat
     1861 gacaaacagt tagctgccaa agaatggttt tccctttggc agtctcaaaa gtttgaacag
     1921 atcagtcgag atgtgcattt ggttttgatt atcgcaagag agaatcacca agtgactcaa
     1981 gaacacgtgt caatcttatt gacctgcgtt caagaattga ttgcggaagt caatcaagta
     2041 cagtcactca gtcgtgggtt tcgtgaaaaa tacatgagat aggaggctac tatggtttat
     2101 cgttatcgta ccaatctcaa aaaagtattt ctaacagatt cagaattaca ccaattgaat
     2161 gaacggattg ctaagagcaa ttgtcaaaat ttttcagtct atgccagaaa agttttgctt
     2221 aatcccaata tgtcatttgt cacgattaac acggatactt atgaccagtt agtttttgaa
     2281 ttgagacgga tcggaaataa cattaatcaa attgcgcgtg ctatcaatca aagccgtctg
     2341 atttctcagg aacagttaca agaattgagt aaaggagtcg gagagttgat caaggaagtg
     2401 gacaaagaat ttcaagtgga agtgaaaaga ttgaaggagt ttcatggtag tcactaagca
     2461 ttttgcgaca cacggaaaaa aatatcgtag gcgtttaatt aagtatatcc tcaatcctga
     2521 taaaacggac aatttgaaat tagtatctga ttttggtatg agcaattact tagactttcc
     2581 tagctatgaa gaaatggtag aaatgtacaa tgtcaacttt accaataatg acaagttgta
     2641 cgaatacaga aatgaccgac aagaaaaaca ccaacaaaat attcatgccc atcacctcat
     2701 tcaatcattt tctcctgaag ataatctgac acctgaagaa attaaccgca ttggttatga
     2761 gaccattatg gaattaacag gaggccgttt tcgtttcatc gtagcgactc atacagacaa
     2821 agatcatatt cataatcaca tcttaatcaa cgccattgac tgtaattcag ataaaaagtt
     2881 gatatggaat tatgccttgg aacgaaacct tcgtatgatt tcagaccgca tttctaaaat
     2941 ggctggggcg aaaattattg aaaagcgttt ctcttaccgt gactatcaaa aatatagagc
     3001 gactagccat aagtttgaac taaagcaacg tctttatttt ttgatgcagc agtcaaaatc
     3061 ctttgatgat tttttagaaa aagcagagca attacatgtt catattgatt ttagtcagaa
     3121 gcatagtcga ttcatgatga cggatcgggc aatgacaaaa ccaattcgag gacgtcaact
     3181 cagtaaacga gatttatatg atgaagattt ttttagaatg cattttacca agcaagagat
     3241 tgcaagtcgt ttagaatttt tgttgaactg tgtcaattct ttagaagggt tactaacaaa
     3301 atcaaaagaa ttgaatctaa ccattgactt aaaacaaaaa aatgtaatct ttatacttga
     3361 agaaaatgga aagcaattca gtctgagtca taaaaaaata agtgatgaga aattatatga
     3421 tgtcaatttt tttcaagatt attttaaaaa taaggaagta ggtgtttcag aaggaataga
     3481 aaatctacag gcacagtacc gtgcttttca agaagaacga gataaggaga aggtatctac
     3541 tgaagaaatt gaggaagcct ttgagacatt taaggaaaaa cgagatgccg ttcatgaatt
     3601 tgaagtaaaa cttacagaac accaaattga gaagttagtt gatgagggga tttatatcaa
     3661 agtgtccttt ggtataaatc agagtggtct tattttcatt cctaactatc aactggatat
     3721 tatggaagaa gaaaatcaga aaaaatataa agtctacatt cgtgagacaa cctcatattt
     3781 tgtctataac aaagaacatt cggataagaa tcagtatatc aaagggagaa ccttgattag
     3841 gcagctaacc aacgatagtc gagtaatacc atacagaaga ccgactgttg aaagacttca
     3901 agaaaagatt tctgagatta gcctcttgat tgagttaact gagacagata agaaatacca
     3961 agacattaaa gacaacttgg tttccgaaat agcagagcta gatataaaac tgactcaaac
     4021 aaatgaaaaa attgccacct taaataagat ggcggaagta cttatcaatt ctaagagtga
     4081 aggttcgggt agccaaaaac tagctaggca tgaattttct aaattgaaca tgacagaatc
     4141 aacaacttta gaacaagtca atgaagaact tttgaagtta caacaggaat ttggtaatgt
     4201 tcttgatgag tatgagaaaa caataagaaa gcttggacaa ttatttaagg tttttgatga
     4261 gtgtatcaat aaagaaatta tgaatgaaat ataaatcaga ctgaagacaa actcaaattt
     4321 ttttggatat cttttctgtt tatggttgcc aatatcggtt taacttctaa aacaaacatt
     4381 aataaaaatg cattcaaaga cgattttacc tattttacga ttacgcttcg accccaaatc
     4441 attaaagttg tctatgctct atcattgcat cactggactt gtcaagagtt aagataattc
     4501 ggagtccact gaaaaagtca tcgtatgatg gtatactaaa gatgaggtga tggtatgctt
     4561 gataatcgat gttagtccct attctactct gtgtgatatt gttgttccca aaactcattt
     4621 tttacgacag ctaatggaac tctgtgattt tagttttatt tatgacgagc tggaaaagaa
     4681 ttatcaacct gacttcggat gtcgttccta ctctctcctt atcatgatgt tcaagtatct
     4741 cttattaaaa gacatctata agttgtccga tgtggatgtg gtggagcgct ccttttctgg
     4801 tatgaccttc aaatacttcc ttggtctagc tcctgttatt gaaccgtcct cattgactaa
     4861 attccgaaaa cttcggaaca aagatgaacg attacttgat ttgctcatcg ctaaatctgt
     4921 tcagattgcg atagagctcg gtctgattaa aagtaacatt ctcattgtgg atgcgactca
     4981 taccaaagtt cattacaatc acaagaaacc tcaagaagtc ctccgagaac gctcaaaagc
     5041 cttgcgtaaa acgatttatc agtattcgga atatatcaag gcagaatttc ctagtaagcc
     5101 tcaggaagat actctagtag ctgaattaag atatacacaa gaagtaatat cagtccttga
     5161 gaagcatgac gaattgactg gaataccagc tatctcacaa aattcaatta ccttaaagaa
     5221 gctgtagagg atgacttaga gcacttggaa tcctctgtca aagaagaagc aagaattgga
     5281 cataagtcag ccgatagttc cttttacggg tacaaagagc attttgccat gaccgatgaa
     5341 cggattatta ctgcctgtgt ggtgacatcg ggtgaaaaaa gtgatggtcc tgttttagaa
     5401 gaactctatc acaaatctaa ggataatggc gtgacgattg aagctattgt tggagatagg
     5461 gcctactctg ggaaggataa tatgcaattt accaagaaag aacgtgtgca ttgagtcgct
     5521 aggccatatc caactatttc aaaaggcttt cgtaggaagg aagatgagtt tttctataac
     5581 aaggacgcag gtctctttgt ttgtccagaa gggcatatgg cactaaagaa ggaaaagaca
     5641 ggaagaagga cggctcagga aacccactat tttgacatca agcactgtca aatatgccct
     5701 tcaaaagtgg gctgttataa agaaggggct aagtctaaga cttatttgat accccttaag
     5761 agcgatgaac atattttcca gaagaggttt caggaagcgc cctattttaa agaaaaggcc
     5821 aaacatcgct acaagataga agccaaaaat gcggaacttg aaaacagaca tggtcttaat
     5881 gtagctagag caccaggtct tttaaacatg gagttacaag ccgccacaac catatttgtg
     5941 gttaatatga agaggattat aactctaata aaccaaaaat aaggaaaagc aaagaggaat
     6001 ctatccaagc aggagataga tccctctttt ttcattttag ttgaactgta gagcttactt
     6061 tttcagtgga ctcgatgatt agtgactatt tttttcaaac tctattagtt attggtaccc
     6121 taatgccgaa tggagatatt taggattgta atagatttca atatatttaa agatttcgtt
     6181 caatagttgc gaaattggca tcattgacaa gttctctttt tatgttttgt aaaaggattc
     6241 catgggtgca ttatcatatg gattgccttt tcgactcagg ctagacttgc atcttttctg
     6301 tttaaggagt tcttgaaatc tagctccagt atattgagat ccttgatcgg tatggccgac
     6361 tagttcttat ttgagatttt ctctatgata agcttgattg aaaacattcg ttaccaactt
     6421 atcttgcatt cgatttccca ttgcctaacc aacaattttt ctgctataaa catatatata
     6481 atgataaata aagagtacct gcttttgtcg gaatataagt taaatccccc agccagattt
     6541 catttttacc ttttgtttga aaacactgat taatcaaatt gggtcgtgtt aatgaggaat
     6601 gccgacggct atagtacttg tatttatagc ggattccttt agcatagaga caaa
//
LOCUS       DAVKEV010000076         6208 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVKEV010000076 DAVKEV010000000
VERSION     DAVKEV010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6208
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.076"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            63..1817
                     /locus_tag="VWZ68_001990"
     CDS             63..1817
                     /locus_tag="VWZ68_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9372960.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNINNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            1801..3522
                     /locus_tag="VWZ68_001991"
     CDS             1801..3522
                     /locus_tag="VWZ68_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9372961.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDVK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            3533..4117
                     /locus_tag="VWZ68_001992"
     CDS             3533..4117
                     /locus_tag="VWZ68_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU9372962.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            4117..4812
                     /locus_tag="VWZ68_001993"
     CDS             4117..4812
                     /locus_tag="VWZ68_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU9372963.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKIAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            4800..6164
                     /locus_tag="VWZ68_001994"
     CDS             4800..6164
                     /locus_tag="VWZ68_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9372964.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGSGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDESSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         2253 a          793 c         1162 g         2000 t
ORIGIN      
        1 tagatattat caattaagcg aatttatatc taaaagggat attaaagaaa ggagatatgc
       61 ttatgaagat ttacaaaaaa ctatttgctt atgtccaaga taagaaatat cttggggttt
      121 tggccataat tttttctgct atatctgctc tacttacagt atatggatat tatttaatct
      181 acaaatttct agataagtta ataattaatt caaatttatc cggtgcagag agtatagcat
      241 taaaatctgt tattacacta acaagtggag cgatatttta ttttgtctca ggaatgtttt
      301 cacacatctt gggatttagg cttgaaacaa atttaagaaa aaggggaatt gatggcttag
      361 agaaagcaag ttttaggttc tttgacttaa atccatctgg tcaaataaga aagatcatag
      421 atgataatgc agcacaaact catcaggtgg tagcacacat gattcccgat agttctcagg
      481 caataatcac acccgtactt gtacttgcac ttggctttat agtaagtata agagttggca
      541 taattttgct tgctcttact ataattggcg gcttaatttt aggggcaatg atgggcgagc
      601 aagaatttat gaagatatac caagaatccc tatctaaact aagtgctgaa actgttgagt
      661 acgtgagagg aatgcaagtt gtaaaaatat ttaaagcaaa tgtagagtct tttaaaagct
      721 tttataaggc gataaaagat tactcaaagt atgcttatga ttattcccta tcttgtaaaa
      781 ggccttatgt tttgtatcaa tggttatttt ttggactgat tgcaatttta attattccta
      841 tagtttattt tatgactagc ttagctagcg caaaggtgat tttacttgag cttatcatga
      901 ttttattttt atcaggagtt ctctttgttt cattcatgag aatgatgtgg tactccatgt
      961 atatttctca aggaaattat gcagtagata ctttagaggc gctttacgaa gatatgcaaa
     1021 aagacaaatt agtgcatggt aatatcaata attttaaaaa ctataatata gaatttgaga
     1081 atgttagctt tgcttataat gataaagctg tcattgaaaa tttatccttt aatttagaag
     1141 aaggaaagtc ctacgcactt gtcggttcat ctggatcagg caaatcaaca gtagcaaaac
     1201 ttatatcagg tttttataat gttaataaag gaagcataaa gataggcggg atagcaataa
     1261 gtgaatattc tgacgaagcc ttaattaaag ccatttcctt tgtttttcaa gattcaaaat
     1321 tattcaagaa gagcatttat gataatgtag ctttagctaa taaagatgcg acgaaagatg
     1381 acgttatgag agccttaaaa ttagcaggat gcgatttaat attagacaaa ttcccagaaa
     1441 gagaaaatac aatcataggc tcaaaaggtg tttatttatc cggtggagaa aaacaaagaa
     1501 ttgcaattgc tagagcaatt ttaaaggatt ccaaaattat tattatggat gaagcatcag
     1561 catctattga cccagataac gagtttgaat tgcaaaaagc ttttaaaaat cttatgaagg
     1621 ataaaacagt tatcatgatt gcacacaggc tatctacaat taaagacctt gatgaaatta
     1681 ttgtcatgga tagtggaaaa attatagaaa gagggtctga caaagaatta atgtcaaaag
     1741 atacaaggta taagagcctg caagagatgt ttaacagtgc gaatgaatgg agggtttcaa
     1801 atgaaagagt tttataaaaa aagatttgct cttacagatg gaggagcaag aaatttaagt
     1861 aaagcaacac tggcttcatt tttcgtttat tgtataaaca tgcttcctgc catattactt
     1921 atgatttttg ctcaggaagt tttggaaaat atgggcaaaa gcaatggctt ttatatagta
     1981 ttctcagttt tgactttgat agcaatgtat attttgcttt ctatcgaata cgataaatta
     2041 tataacacaa cctatcaaga aagtgcagat ttaagaataa ggacagcgga gaatttatca
     2101 aaattacctc tatcttactt ttctaaacat gacatttccg acatttcaca aacaatcatg
     2161 gctgatattg aaggcataga gcatgcaatg agccactcaa taccaaaggt gggcggcatg
     2221 gtactgtttt tcccattaat atctgtaatg atgctagcgg gcaatgtcaa gatgggttta
     2281 gctgtaatta ttccatctat tttaagcttt atatttatac ctttatctaa aaaatatcag
     2341 gttaatggac agaatagata ttatgatgtc ttaagaaaaa actcagaaag ctttcaagaa
     2401 aatatcgaaa tgcaaatgga gattaaagca tataatttat cgaaggatat taaagatgac
     2461 ttatataaaa aaatggaaga tagtgagaga gtacacttaa aggcggaagt aactacaatt
     2521 ttaactttgt ctatatcttc aatatttagc tttatatctc ttgctgttgt gatatttgtc
     2581 ggcgtaaatc taattattaa taaagagata aattctctct accttatagg atatttacta
     2641 gctgctatga agataaaaga ctctttagat gcatctaaag agggcttgat ggaaatattt
     2701 tatttatcgc ccaaaataga aagattaaaa gaaattcaaa atcaagattt acaagaaggc
     2761 gatgactata gcttaaaaaa atttgatatt gatctaaaag atgttgagtt tgcctacaat
     2821 aaagacgcaa aagttttaaa tggtgtaagt tttaaagcta agcagggaga ggtcactgct
     2881 ttggtaggtg caagtggctg cggtaaaaca actatcttga aacttatatc aagactttat
     2941 gattatgaca agggacaaat cttaatcgat gtcaaagata taaaagaaat atcaacagaa
     3001 tctctttttg ataaggtctc tatagttttc caagatgtgg ttctctttaa tcaaagcgtt
     3061 atggaaaata ttagaatcgg aaagcaagat gcaagtgacg aagaggttaa aagagcagca
     3121 aaacttgcaa attgcacaga ttttatagaa aaaatggata aaggtttcga tacagttatt
     3181 ggtgagaacg gagctgagct atcaggagga gaaagacaaa gattatcaat agccagagcc
     3241 ttcttaaaag atgcgccgat attgatctta gatgagataa cagcaagcct tgatgttaac
     3301 aacgagaaaa agattcaaga gtctttaaat aatttagtta aagataaaac tgttgtaatc
     3361 atttcacata gaatgaaatc catagaaaat gcagacaaga tagtagttct tcaaaacgga
     3421 agagtagaaa gcgaaggtaa gcatgaagag cttttacaaa aatcaaaaat ttacaaaaat
     3481 ttaatagaaa agacaaaaat ggcagaagaa tttatttatt aggaggacta caatggataa
     3541 taaaaaatta aaagtaaaag atttagtaag tatcggtgtt tttggcgtaa tttattttgc
     3601 cttcatgttt ggagttggta tgatgggctt gattccaata ttgttcttaa tatacccgac
     3661 agtattagcc atagttgcag gaactgttgt tatgttattt atggctaagg ttcaaaagcc
     3721 atgggcacta tttatatttg gtatgatatc accacttgtg atgtttgcag ctggtcatac
     3781 ctacgtagtt gtggttttat cacttatagt aatgataata gcagaattaa ttagaaagat
     3841 tggtaattat aattcattta aatacaatat gctttcttat gcaatcttca gcacatggat
     3901 atgtagctct ttaatgcaaa tgcttttagc aaaagaaaaa tatatggagt ggtctttgat
     3961 gacgatggga aaagattatg ttgatgtatt agaaaagtta ataacttatc ctcacatggc
     4021 tttagtagcc ttaggtgctt tcttaggagg aattcttgga gcatatatag gcaaggctct
     4081 attgaaaaaa cactttgaaa aagcaggcat cgtataatgc ctactttttc ttcaaatgct
     4141 ccctttaatc ccaatccgat ctctaagata ttagtcgtat ttatcacagg cttaactgtt
     4201 atgcatagca taaacatccg ttttgagctg gcaattgttt gtcttattgg tattttgctt
     4261 tatttgaatg gatacaaaaa aacacttttc aaatggatta tattgtgtgg gatactttac
     4321 tccttgccta attttatggt gttatctgaa ttaaacccta tagttaagat gtttttgagt
     4381 atacctattg ttattagaat gtttatttta ccatttatgg cagcaagctt tatgataaag
     4441 acctcggatg taggcgcaat aatttcatcg atggataagc ttaagatttc aaagaatgta
     4501 tccataccta ttgcggttat gtttagattc ttcccatctt ttaaggagga gaagaaaaac
     4561 atcaaaatag ctatgagagt aagagggata aattttaaaa acccagtcaa atatcttgaa
     4621 tatgtttctg tgccactact cattatatca tctaatatat cagatgacat tgcaaaagcg
     4681 gcagaaacaa aggcaataga aaatccaatt gccaagacca gatacattcg cgtaaagata
     4741 cagctaattg attttgttta tgttttagcg gttgctggac ttattgtggg aggcttaata
     4801 tggttgaaat aaaaaattta agtcttgatt atggtgaaga gcatatatta gatgatatat
     4861 cactatccat agccgaggga gagtgcgtgc tatttacagg aaaaagtgga agtggtaagt
     4921 catctttaat aaattcaatc aatggactag ctgtaaggta tgataacgca aagacaaagg
     4981 gcgaaataat tattgatggt aagaatataa aaaatttgga actttatcaa atctcaatgc
     5041 ttgtttcaac tgtttttcaa aatcctaaga catatttttt taatgtcaat acgacattag
     5101 aattattatt ttatttggaa aatatcggtc ttgcaagaga agagatggac aggcgtttga
     5161 aggatatgct tgagatattc ccgataaaaa atcttttgaa cagaaatata tttaatctat
     5221 ccggcggtga aaaacaaatt ctttgcattg cagcttctta tatagcaggt acaaagatta
     5281 tagttatgga tgagtcttca tcgaatttag atattaaaag cataagtgtt ttggcaaaga
     5341 tgctaaagat attaaaagag aaaggcataa gcataattgt tgcagagcat agaatttatt
     5401 atttgatgga catagttgac cgtgtatttt taatagataa aggaaagctt aaaaaaactt
     5461 atactagaag tgaattttta aagctagata aaaatgaatt aaatgcttta agtttaagag
     5521 ataaagaatt aagtaaatta aaagttcctt atttaaaaga aggtggagag tatcagataa
     5581 aaaatcttag ctacaaattt actgatgatg agtgtttaag cttaaaagat atttcgttca
     5641 agcttgggaa aatttatggc ataataggat ccaacggacg aggaaaatca acgcttttaa
     5701 gatgtttaat aggtcttgag aaaaaatcaa aagaagaaat ttattttaag ggagagaagc
     5761 tatctaaaaa agaaagactc aaaaactctt cacttgttat gcaagatgta aatcatcaat
     5821 tattcacaga tgaagtattc aacgagctta gattaggagt aaagaatttt gatgaagaaa
     5881 aggcgaaaat cattttaaaa gatttaggcc tggacgaatt tattgaaagg catccgatga
     5941 gtttatcagg agggcaaaag caaaggcttg caatagcatc tgttatgtgc aagaattctc
     6001 catttgtctt ttttgacgaa ccttcaagtg gtatggatta ttccaatatg ataaaaatat
     6061 ctgaactgat taataagtat aaaaccatgg ataaaataat ttttattgtt tcccatgata
     6121 tagaattttt aaatgaagtg gcagatgaaa tttttgaatt gtaaaataga gtctgttaaa
     6181 catgtctata gaactggtaa attgtcta
//
LOCUS       DAVKEV010000077         6107 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVKEV010000077 DAVKEV010000000
VERSION     DAVKEV010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6107
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.077"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(112..387)
                     /locus_tag="VWZ68_001995"
     CDS             complement(112..387)
                     /locus_tag="VWZ68_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEU9372965.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(494..1333)
                     /locus_tag="VWZ68_001996"
     CDS             complement(494..1333)
                     /locus_tag="VWZ68_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU9372966.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1475..2323
                     /locus_tag="VWZ68_001997"
     CDS             1475..2323
                     /locus_tag="VWZ68_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU9372967.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2416..3333)
                     /locus_tag="VWZ68_001998"
     CDS             complement(2416..3333)
                     /locus_tag="VWZ68_001998"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEU9372968.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3679..3887
                     /locus_tag="VWZ68_001999"
                     /pseudo
     CDS             3679..3887
                     /locus_tag="VWZ68_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4197..4490)
                     /gene="rpmA"
                     /locus_tag="VWZ68_002000"
     CDS             complement(4197..4490)
                     /gene="rpmA"
                     /locus_tag="VWZ68_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEU9372969.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4507..4851)
                     /locus_tag="VWZ68_002001"
     CDS             complement(4507..4851)
                     /locus_tag="VWZ68_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEU9372970.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4867..5181)
                     /gene="rplU"
                     /locus_tag="VWZ68_002002"
     CDS             complement(4867..5181)
                     /gene="rplU"
                     /locus_tag="VWZ68_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEU9372971.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5217..5304)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5369..6067)
                     /locus_tag="VWZ68_002003"
     CDS             complement(5369..6067)
                     /locus_tag="VWZ68_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEU9372972.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
BASE COUNT         1863 a         1249 c         1021 g         1974 t
ORIGIN      
        1 aatattttcg gaacattcaa ctttttaact ctatttatta ctagatttca taattaaaaa
       61 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
      121 agcgtcttta agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat
      181 ttctttacca gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt
      241 accaaaaccg atcaactgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa
      301 tacagcttca actgctgctg ctgagtcttt cttagttaat tctgtagctt ctgctacttt
      361 agcgatcaaa tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac
      421 aaatataatc atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat
      481 tttatttatt tttttaggag tggtaacgta tcaaaatagc ccaagcgttc tcacccgtgt
      541 gagtttgaat aatggaaccc gtttccaaaa cagaaattgg cttttcaaca taagcttgta
      601 agctttcttt catctctttt gcccaatcat cactaccaga atatgaaatt ccaatctctg
      661 ctacagcacg ttcagaaagc gatgttatca actcatctaa ccatttttta aatgttttag
      721 ttccacgacc tttaaccatt ggctgcaatt catggtcttt catttgcatg acaacacgga
      781 tattgagaag agagctcaac aagccagtta cacggctaat tcgtccacct ttgacaagat
      841 tttccaaagt tgaaacacca atataaagct ctgtatggtt tttaacctct tctacatgag
      901 ataaaattgc ctccatatct ttaccttctt gagctaactt cgcagcctca acaacttgga
      961 atttcagggc ttggtcagtg aaggaactat caacaacagt cacatctgca gtagataggc
     1021 tagcaccttg gcgtgctgct tctaccgtac ccgaaagagc atgggacata tgaatagcaa
     1081 gaatctggcc accatctttg cataggtctt caaaaatctc agcaaagaca cctacaggtg
     1141 gctgacttgt tttcggaaga ttcttacttt cttgcatcaa ctgaagaaat ttaccttctt
     1201 ctttcaaatc cgcatcagaa taaacaacat tatcaatcat tacagataat ggaacaattg
     1261 taatatctaa ttgctttact agttcaggtt caatagtaac agatgaatcg gttacaatct
     1321 taatttttgt catagtatca atctttctat tttaggattc agattggttt ccttacttct
     1381 aattatatca aaaaaaagat taaaaatcct aatggagtca atcaaatttt ccgtaaaatt
     1441 tgatataatc aacttataag aaaagaggtg tcctatgatt aaaaaaattt accccatttt
     1501 taccatttta ctaggtgctg ctatttatgc ttttggactg acttattttg tagttcccca
     1561 tcatctcttt gaaggagggg cgacaggcat taccctcatc accttttatc tttttaaaat
     1621 ccctgtttcc ctcatgaacc tgctgattaa tattcccctt ttcatcctag cttggaagat
     1681 ctttggagcc aaatccctct attctagttt actaggaacc ttagctttgt ccgcctggtt
     1741 agcttttttt gagcatattc cccttcatat tgatcttcaa ggtgatttac taatcacagc
     1801 ccttatagcg ggaatcctat tgggaattgg ccttggaatt atttttaatg ctggaggtac
     1861 aactggcgga actgatattc tagctcgtat tctcaacaaa tacactcata tatccatagg
     1921 aaaactgctc tttatcttag atttttgtat tctcatgttg attctcctaa tcttcaagga
     1981 tttgagattg gtttcctaca cgcttttgtt tgattttatt gtttctcgtg ttattgattt
     2041 gattggtgaa ggaggatatg ccggcaaagg ctttatgatt atcacaaaac gtcctgacca
     2101 acttgctaag gcgattaatg atgacctcgg aagaggtgtt acttttattt ctggtcaagg
     2161 ctactatagt aaagaaaatt tgaaaatcat ctactgtatt gtcggaagaa atgaaattgt
     2221 gaaaacgaag gaaatgattc atcgaatcga tcctcaagcc tttataacta ttacagaagc
     2281 ccatgaaatc ctaggagaag gcttcacctt tgaaaaagaa taaaaagagg taatgtcgtg
     2341 acctcaaaag ttagactaaa tcatctatct tttgggttac agacaacctc ttttttgttt
     2401 tatttactca agctcttaag accaattccg agttacttct tcatcagcct ttaactgatc
     2461 cactaattgg tcaactgagt caaatttggt catatcacga atgcgatcaa gccaataaac
     2521 catgacggtt tccccataaa tatcttgatt aaaatcaaaa atattgactt caaaacgtgc
     2581 ttcttctcca tcaaaggtca catttttccc gacactagcc atagcacgat acttctgtct
     2641 ttgaatctca acatcaacga cataaacgcc atctgctggc atataagtac ggtctaaaag
     2701 cactaaattc gctgtcggat aaccaattgt acgaccacga gcattaccat gaactaccat
     2761 acctcttgat ggaagcggtg cccccaaaag ttttcctgct tctttcacat ttccatctaa
     2821 aatagcttga cggatacgag ttgaactaat ctttcctttc tcatcttcta caggtggaac
     2881 aatgataact tctccatcaa agtaatcctt taaatcttct gctgtttttt tgtcagaacc
     2941 aaatgtataa tcaaaacctg caacaataat tttggcattc atagccttga tataagttgc
     3001 aaagaattct tgtgcagtaa gactagcgaa ttgactacta aaatcaagga gatataattc
     3061 ttctacacct tcgcgcttta attttctttc acgttcagca gggttcaaaa tatgcaaaaa
     3121 caaatctgga tgataaggct ctaaagcgat ctttggagat tcattaaagg tcataacgac
     3181 gataggtaat aaatcctttc tcgcagcctt gttggcaaca cgaaataatt cttgatgccc
     3241 cttatgtatg ccatcaaaat agccgagaac aacgactgaa tcagatggtg tgccaatatc
     3301 tttttggttt tttataggaa tagtaataat cataaaataa ttatatcata gcgatagcta
     3361 tttctggaac agaaaatctg aaatgttgtt tttttcacat gaagtgtacc tgttttcaaa
     3421 aagcacttta ttctatcgtt gcttaactat gaactttgca atattcttct caaaaacttg
     3481 taggacatct tcaaaatttt gcaaggagtg attagacttg ttcggtaacc ataaagtgtc
     3541 atactatgtt atgtatgaaa aagcaatgca actaactcct gagaacttta aattactaat
     3601 tggtgccgaa aaggtagaat ttagaatcga ggtacaccta tggctgtaaa atttacaaaa
     3661 tgagacaact tgggcaagat gtttgaagaa tttcctaaac tcccatctag tgtgcttcag
     3721 actaggctat ttttctctcc atctgttagc ttggattctc agaccgtttc agctaaagaa
     3781 tatcttttcc cttatcagaa ggaacggctc aagccattca gacaagtgaa gggacgacaa
     3841 gccaatattt gaaaccagat agcagttctt atagtcaatt gaaataaaat ctgaagaaat
     3901 cgagtaggaa actcatatca atttttaaca gtgttctatt ccagattcat actcaatgaa
     3961 aattaaagtg caaactagga agttagccgc aggctgtact tgagtacggc aaggtgaaat
     4021 tgacgtggtt tgaatttgat tttcgaagag tatcaatcca ctatacatat taaaaagtat
     4081 gggtatcaaa ataaaaaaca ggctctccga aaactcggaa agccttattt taagctgttt
     4141 ctagcttcct cacctttaca tttcaaggtt cgggataaaa ggttcaatgg acctttttat
     4201 ttagcgattg ggtaaacaga aacttgtttt ttatcgcgtc ctttacgttc aaagcgtact
     4261 acgccttcaa ctttagcgaa caaagtatcg tctccaccac gaccaacgtt tacacctgga
     4321 tagatgtgtg taccacgttg acggtaaagg attgatccac ctgttacagt ttgtccgtca
     4381 gctgctttag ctccaagacg ttttgcttgt gaatcacgtc cgtttgatgt agaacctcca
     4441 ccttttttgt gggcgaaaag ttgcaagttg ttaagagtca tttttaacat aatgttttcc
     4501 tccgtgttag ttttctgtga taactctggt ttggacgaac tcagaatagt tctccgataa
     4561 gtttgccata cctaagaaaa atgattcaaa gaataactgg gtcatttctc tctggtgtga
     4621 aggaagatct tttggtattt caaccatcag atagccacct tcatcttcgt ttaattctag
     4681 gattggttca tagcctgcaa atttctcaat agaattgata aagttaatgg caagcgtaga
     4741 aaccgatgca cacacgacat ctaagccgta ttcgccactc tcggcgtgtc cagtaatttc
     4801 cgcactcctc agctcgccat cttcggctct ctcaaagact gcctgtatca tgtgttctcc
     4861 ttaaaattaa gcgttgattg cgttgatgac aacttttgta tatggttgac ggtgaccttg
     4921 tttacggtgg ctaccttttt taggtttgta cttgtaagta accactttct tttgttttcc
     4981 ttgtttttca acagttccaa ctacagtagc tccagcaaca agtggagttc cgacaacagt
     5041 gttttcacca ccaacaagaa caacttcgtt aaaagtaact tcttgaccag cttcaacgtt
     5101 caatttttca acgtaaactg cttgaccaac ttcaacttta acttgttttc cgccagtttt
     5161 gataattgcg tatgtgctca ttatgcacct cctatgattt ttatgggttt ccccgatttt
     5221 ttgtgaagac tcgcctagca tcgtgggacg aaccacttaa acttgaataa tcaagcaacg
     5281 atgttcgtgc ggttgcacag gatcgtgcat agtcaactct tcaagtatag catatctcct
     5341 attttcttac aagtaataac acctaaaatc aagctttttc ttttactttt ttctgccaag
     5401 aggcaaaaag catgctgagg taaaaaacgc tcatcataat aggaacacca agaatggtct
     5461 tttcatgata gaaaatcgtc aaataggctg aaaagacaac gccaaggaca aaactactaa
     5521 gcaggctaac aaatatgaat ccttcacgca aaaaaggagt gtgcttggtt cggaaataat
     5581 ctccaaaagc cagcatggtc cgtttgatat tccctgtcat aaaagcgtta ttataggcaa
     5641 tacccgacac ttctccaaaa gcagttgtca ccagtcccat acagaaggcc aagggcggca
     5701 ctagatagat attatccaca gtttgcggca caaaagcaat aatgattgat aagattgcca
     5761 agggaatcaa ggacagaata ggttttttca caattctcaa tttttcctta taaatcgtta
     5821 ataaaaagac tcccatcata aacgctagca aggtgagaac cttgtcccta acatccgaaa
     5881 cattattttt aattaattct actgaaagaa agacaacatt tccagtttgt ccagctacaa
     5941 gggtattccc gcgaacaata aaagtgtaag catccacata tccagcacaa aacgtcaaaa
     6001 aaagtgctaa ccttttagac tgacgtgata tttttcttat aggtaataac ctcattttac
     6061 ctcccattgt attttctctt agaaatattg taccattttc tttctaa
//
LOCUS       DAVKEV010000078         6062 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVKEV010000078 DAVKEV010000000
VERSION     DAVKEV010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6062
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.078"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            67..309
                     /locus_tag="VWZ68_002004"
     CDS             67..309
                     /locus_tag="VWZ68_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEU9372973.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            311..565
                     /locus_tag="VWZ68_002005"
     CDS             311..565
                     /locus_tag="VWZ68_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU9372974.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHWRDIY"
     gene            612..1264
                     /locus_tag="VWZ68_002006"
                     /pseudo
     CDS             612..1264
                     /locus_tag="VWZ68_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
     gene            complement(1524..2510)
                     /locus_tag="VWZ68_002007"
     CDS             complement(1524..2510)
                     /locus_tag="VWZ68_002007"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEU9372975.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            2704..5172
                     /gene="gyrA"
                     /locus_tag="VWZ68_002008"
     CDS             2704..5172
                     /gene="gyrA"
                     /locus_tag="VWZ68_002008"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEU9372976.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            5172..5915
                     /gene="srtA"
                     /locus_tag="VWZ68_002009"
     CDS             5172..5915
                     /gene="srtA"
                     /locus_tag="VWZ68_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEU9372977.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKEIKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         1916 a          989 c         1315 g         1842 t
ORIGIN      
        1 tttatattga ctgaacacct aaaaagtaat acaatggtgt taccattaaa aaagggagca
       61 caaaagatga ctactattac attaaaagtt tctgaagctg ataaaacatt tatgaaagca
      121 atggctaagt ttgaaggagt ttccctttcg gaacttattc gcaccaaaac tcttgaagcc
      181 ctagaagatg aatacgatgc tcgtgtggca gatttagcct atcaagagta tttagaagac
      241 ttggaaaaag gagttgaacc cattacttgg gaagaaatga tgcatgattt aggcttgaag
      301 gatgaataat ttgtataaat tagttccaac aagacgtttt atcaagcaat tgaaaaaatt
      361 ggaccgttat acgcagaagc taattacaaa ctatttacaa accaatgttt tggaagaccc
      421 aagacgacac ggaaaggctt tggttggtaa tcgcgttggt caatggcgct atagaattgg
      481 taattatcga gttatcgtac aaattgtaga tgatgaatta gttgttgcta ctctagaagt
      541 tggtcattgg agagatattt attgaattaa agctgagtaa taacagtata gaaagtaagg
      601 atagtaaaaa tttgaataaa aaatggttat ttgcagatta ttatgatata acaattattt
      661 tacttgcttt aatctctgtt attctggtat tacttggatt tgctgagatg attgatttgg
      721 acaatccgcc ttatagtatt attgatttag taatctgggg tgtttttgta attgattata
      781 gttggcgctt ttttattact aaaagaaaat ggcgctttat tcttgaaaat atttttgatt
      841 tattgactat tctcccttta aatgctattt ttacagtgtt tcgattagga cgtatcttcc
      901 gcttagcaag gctgacaaaa ttactgaaac tgactcgttt acttagaata attggactta
      961 caggtaaatt agaaagaaaa attagtagat tcttacgaac aaatggattg atttatatct
     1021 tgtatgttaa tatctttatt gttctagtag ggagttcgat tttatccgtt gttgaagaaa
     1081 aatccttctc agatagtctt tggtgggctc ttgtgacagt aactactgtt ggttatggtg
     1141 atattgttcc agtttccctt tttgggaaga cgaattatcg agccaaagaa tattaataga
     1201 gaaacaatcc gagaagatag aagaactgca tcggatgata caagatttgc ttgaaaaaac
     1261 ataataaaaa taaagatgag acaaagtttg agttgaggag aaatcaagta agttttgaca
     1321 caatagaacg catattatca ggtataaaaa cttgatacta tgcgttttat agagaaatga
     1381 aataaaatct gaacaaatca attaggaatt taaagcattt tataacaacg ttttagagta
     1441 atggggggct atttcaactt caacctacta taatacagaa aaaaacaact ccctgataat
     1501 tcaaggagtt gtctatagtt aaattagttt ttagaagctt cttggaattc tgggtttttc
     1561 catgcttcgt caatgatagc ttgcaattct ttagcagatg cttgcatttt ttgagtttct
     1621 gcgtcgttca atgggatatt tactggacga acaataccat gtgcaccaac aacagctggt
     1681 tgaccgataa agacgttctc aactccgtat tgaccttctt ggaatactga aagtggaagt
     1741 actgcatttt catcgtcaag gattgcttta gtgatacgag caagggctac tgcgataccg
     1801 tagtatgttg cacctttttt gttgatgatt gtgtaggctg catcacgaac accttcgaac
     1861 aattcaatca attcagcttc ttgaacattt tgagtatctt taaggaattc ttcaaggttt
     1921 acaccagcga tgttagcgtg tgaccaaaca gcgaactcag agtcaccgtg ttcacccatg
     1981 atgtaggcgt gaactgaacg agcatctacg tccaattttt cagcaagtgc ttgacggaaa
     2041 cgagctgagt caagtgaagt acctgaaccg ataacgcgtt ctttagggaa accagagaat
     2101 ttccaagttg agtaagtcaa aacgtcaact gggttagcag caacaaggaa gatacctttg
     2161 aaacctgatt caacaacttg agttacgatt gatttgttga tagcaaggtt tttacctaca
     2221 aggtcaagac gagtttcacc tggtttttga ggcgcacctg cagtgatcac aacaaggtca
     2281 gcgtctgcac agtcagagta ttgagctgca tagatttttt taggtgaagt gaaggcaagg
     2341 gcgtgactaa ggtcaagcgc atcaccaaca gctttttcat gcaattgtgg aatttcgata
     2401 attccaagct cttgtgcaat tccttggtta acaagtgcaa aagcgtaaga tgaacctaca
     2461 gcaccatcac cgacaaggat aacttttttg tgttgtttag ttgaagtcat tgttttaaac
     2521 atctccttaa ttttattagg ggattttccc tagacaactt cattctatca cttttaaaaa
     2581 actttgtcac gaatatgcct tatagttctc gatgtaaacg ttttagtggt ttagaggctg
     2641 aaatagatgg gaatttatgg tataatgttg ttacttacta attgtgaaat gaggcattta
     2701 ttaatgcagg ataaaaattt agtgaatgtc aatctgacaa aggagatgaa ggcaagtttt
     2761 atcgactacg ccatgagtgt tatcgtagcg cgagctcttc ctgatgttcg agatggctta
     2821 aaacctgttc accgtcgcat tctttacgga atgaatgaat tgggtgtgac cccagacaaa
     2881 ccccataaaa aatctgctcg tattacaggg gatgtcatgg gtaaatatca cccacacggg
     2941 gattcctcta tttatgaagc catggtccgt atggctcaat ggtggagcta ccgttacatg
     3001 cttgtagatg gtcatgggaa ttttggttcc atggatggag atagtgctgc cgctcaacgt
     3061 tataccgagg cacgtatgag caagattgct ctggaaatgc ttcgtgatat caacaaaaat
     3121 acagttgatt tcgttgataa ctatgatgcc aatgaacggg aacccttggt cttgccagcg
     3181 cgttttccaa accttttggt taatggagca actggtatcg cggttgggat ggcaaccaat
     3241 attccacctc ataatctggg tgaaaccatt gatgcagtga agttggtcat ggataatcct
     3301 gaagtgacta ccaaggactt gatggaagtc ttgcctggac cagattttcc aactggtgct
     3361 cttgtcatgg ggaaatcagg tatccataag gcttatgaaa caggtaaagg ttcgattgtc
     3421 ctacgttctc gtacagagat tgaaacgact aagactggtc gtgagcgcat cgttgtaaca
     3481 gaatttcctt acatggtcaa taaaaccaag gtgcatgagc atattgttcg cttggttcag
     3541 gaaaaacgca ttgagggtat cacagcagta cgtgatgagt caaaccgtga aggtgttcga
     3601 tttgttattg aagtcaagcg cgacgcctca gccaatgtta ttctcaataa cctcttcaaa
     3661 atgacccaaa tgcaaaccaa ttttggtttc aatatgctcg ctatccaaaa tggtataccg
     3721 aaaattttgt ctcttcgtca gattttggat gcttatatcg agcaccaaaa agaagtggtt
     3781 gttcgtcgta cacgttttga taaggaaaaa gcggaagcgc gcgctcatat cttagaaggt
     3841 ctcttgattg cgctagacca tatcgacgaa gtgattcgta tcatccgtgc tagtgaaacg
     3901 gatgcggaag ctcaagctga gttgatgagc aagtttaagc tttctgaacg tcaaagtcaa
     3961 gctatccttg atatgcgtct tcgtcgtttg acaggtttgg aacgcgataa gattcaatct
     4021 gagtatgatg acctcttggc tctgattgcg gatttagcag atattcttgc taagcctgaa
     4081 cgtgtttctc aaattatcaa agacgaattg gatgaagtta aacgtaaatt ttctgataag
     4141 cgccgtacag agttgatgat tggacaggtc ttgagtctcg aggatgagga cttgattgaa
     4201 gaatcggatg tcttgattac cctttctaac agaggctaca ttaagcgttt ggatcaggac
     4261 gagttcactg ctcaaaaacg tgggggtcgt ggtgtccaag gaacgggagt gaaagatgat
     4321 gactttgttc gtgagttagt gtcaactagc acccatgatc atctgctctt cttcacaaac
     4381 aagggacgtg tctatcgtct taaaggttat gaaattcctg agtatggtcg gactgccaaa
     4441 gggctaccag tagtcaatct cttgaaattg gatgaagacg aaagtattca gacggttatc
     4501 aatgttgagt ctgatcgcag tgatgatgct tatctcttct ttacaacccg tcacggtatt
     4561 gtgaagagaa ctagtgttaa ggagtttgcc aatattcgtc aaaatggtct caaagcgctg
     4621 aatttaaagg atgaagatga gttaatcaat gtcttgttgg cagaaggaga tatggatatt
     4681 atcattggta ccaagtttgg ttatgcagtt cgctttaatc aatcagccgt tcgtggtatg
     4741 agtcgtatcg ccactggtgt gaaaggtgtt aaccttcgtg aaggagacac agttgttggt
     4801 gccagcttga ttactgatca agatgaggtt cttattatca cagaaaaagg atatggtaag
     4861 cgtacagtcg ctactgaata cccaacaaaa ggtcgtggtg gtaagggaat gcagacagct
     4921 aaaattaccg aaaaaaatgg cttgctggcc ggtcttatga ctgttcaagg ggatgaggat
     4981 ttgatgatta tcactgatac aggtgtcatg attcgaacca atcttgccaa tatttcacaa
     5041 acaggacgtg caactatggg agttaaagta atgcgcctgg atcaagatgc tcagatagtg
     5101 actttcacaa cggttgcggt ggcagaaaaa gaagaagttg ggacagaaaa cgaaacagaa
     5161 ggtgaagcat aatgtctcaa aaaaataata aaaagaaaaa caagcgaaaa aatctgctga
     5221 caaatatcct agcaggattt ctgatattac tgtcactggc tttgattttt aatactcaaa
     5281 ttcgaaatat tttcatagtc tggaatacca ataagtatca agttagccag gtatcaaaag
     5341 aaaaattaga agaaaatcag gatacagaag gcaattttga ctttgattct gtcaaagcta
     5401 tctcttcgga agctgttcta acttctcaat gggatgctca aaaattacca gttattgggg
     5461 gaattgcaat tcctgaattg gaaatgaatt tgccgatttt taaaggactt gataatgtta
     5521 atctcttcta cggagctggt acaatgaaac gcgagcaagt aatgggagaa ggaaattata
     5581 gtctagctag tcaccatatc tttggtgttg ataatgctaa taaaatgtta ttttctcctt
     5641 tagataatgc taaaaatggc atgaagattt atctaactga taaaaataaa gtttatactt
     5701 atgaaatacg tgaagtcaaa cgtgtgacac cagatcgtgt tgatgaagtt gatgatagag
     5761 atggggtcaa tgaaatcaca ttagtaacct gtgaagacct tgctgctaca gaacgtatta
     5821 ttgtcaaagg tgatttgaaa gaaataaaag attattcaca aacatctgat gaaatcctaa
     5881 cagctttcaa tcaaccatat aaacaatttt attaatacaa atcagtgaaa tcatggattt
     5941 cactgatttt ttaagatttt cataaaaata tagtaaaatg aaataagaat aggactaatc
     6001 gttcaggaca gtcaaatcga tttctaacaa tgttttagaa gtagaggtgt actattctag
     6061 tt
//
LOCUS       DAVKEV010000079         6004 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVKEV010000079 DAVKEV010000000
VERSION     DAVKEV010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6004
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.079"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..1708
                     /gene="lanM"
                     /locus_tag="VWZ68_002010"
     CDS             <1..1708
                     /gene="lanM"
                     /locus_tag="VWZ68_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type 2 lantipeptide synthetase LanM"
                     /protein_id="HEU9372978.1"
                     /translation="IRLYSEYAKNSEWYKFAEGSFEIFRKHPQRINFKKDFSRILEPF
                     IINLLKLINNYLENKEYEWIDKNGNIFSSLVFYLEDLIYPWIVKPLVLEINSLREKGL
                     LEGESEQQRYKYFITLFDKEENILNFYNKYPVLLRQISESCLRFYTYFIEILSNLEND
                     FSVLEEELGLRGKLNDIKFGKGDTHSQGKTVLILFFDDAKIVYKPKNLIINNSLNTIA
                     EYIRKVDEKIRIRIPRTIAYSDHSYEEFIDYLPLEQKKNLPEYYYNFGVLLAFIYLFN
                     GSDIHFENLISYGDMPVIIDFETMLQQPLFDDKTGQSLLDTLFHRVTRTLLLPTEGVK
                     REDGLDVEMSALTGNFKKDAFNGQVLINLNTDKVKFDIGKIDFEGGKNLPVRDGDIEF
                     DKYIKDFKKGFRDFYLIFEELNKTEEFKMLLKANLYGLKTRVLFRDTNSYASVLSFLY
                     HPDFYEEMLDREKALENLWSNKFSNQGIVASECEQMRLLDIPIFYTDTNINEIYDDFG
                     NHFISLHQFSGYDYFMKYLPNNNLENLEKQLDIIEIYFPSFDQRKKGYKLNLSNRKKT
                     PK"
     gene            1758..2768
                     /locus_tag="VWZ68_002011"
     CDS             1758..2768
                     /locus_tag="VWZ68_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin formation protein"
                     /protein_id="HEU9372979.1"
                     /translation="MVINNIYDEYPIWSIPVNFKGSKWCLEQTGNDMYRGRAGILLFM
                     YYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKTTFGLTGDIGYFIVLSIIEDYDTNTLA
                     CLNYIKSVLTELEKTDFASVSNKSDYINGLLPLINTLVRYYRRGIEKERVLRLVLSLG
                     DTLYNDVSERDNSNFGYSFGHGLSGVIFTLKNIYKVTRLKKYKELILQLVPREKIKIH
                     SLKWCSGEFGTLVNHPQSVPEGIVASLDNDTFCHGSMAIINFYIDYMKEMDTSMELES
                     LLCSVVMNKSKEGEYRIVQTSNFPDFSLYTGVTGIAYTFLRYIALNQNDKKIVIPSLL
                     EI"
     gene            3118..3822
                     /locus_tag="VWZ68_002012"
     CDS             3118..3822
                     /locus_tag="VWZ68_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HEU9372980.1"
                     /translation="MNKIFIYAGVRNHNSKTLEYTKRLSSIISSRNNVDISFRTPFNS
                     ELEISNSDSEELFKKGIDRQSNADDGGVIKKELLESDIIIISSPVYLQNVSVDTKNFI
                     ERIGGWSHLFRLAGKFVVTLDVAESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKD
                     IAEAQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKMYWEKKRL
                     FEANSLEEWYYVENIK"
     gene            3803..4732
                     /locus_tag="VWZ68_002013"
     CDS             3803..4732
                     /locus_tag="VWZ68_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HEU9372981.1"
                     /translation="MLKILNNSVIYLCLIPLLFLLLIIFPNDSLIYYFRLILISLISI
                     TLHELGHFLVGRCLSYKLEMLATPFFFYFRKKIYFKFPVLLAFGYCQMSNRNITNEKN
                     SDRNLVFYFFGGGGANLIVAILALLGFVPYASEFFILNIILFLVTVCLPIDGTDGNAI
                     REIVLYSKDSKTYQRFFANSLYNNPYITIDDFAKLTSKEKSFFSKFEKCLINLYFEVK
                     GEGSAFTIANHEVFDSNIQENIIHEYYKLLHKSSDWIIPQNLSLEEVVFTLSNYIYSK
                     NNKYLEKIKYLKKLVDFRQEEIIDFILNKEEVL"
     gene            4729..>6004
                     /locus_tag="VWZ68_002014"
     CDS             4729..>6004
                     /locus_tag="VWZ68_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEU9372982.1"
                     /translation="MKIPMIYQMENSECGLACCAMILNYFKYEISLNELREIYPSSRS
                     GYSLLSISKVLGDFNISSHAFKASVRDLKPLSFPLICFWESSHFIILEKISKNKFYIL
                     DPAKGRQRMSISEFERHYSNIILTFKKLDSFMSRKDNKKSPVLKYFFKYRNKLGILFF
                     VTALLYVIQSLVPIANRYIIDTNFKDDSYSSRMLFTILFIFTVSFSLMYLLRQIYVAS
                     LKYIMDKEISYDFMKHLIYLPYSFYEKRTLGDILFRANSIVYIREILSNNFIAAILDL
                     LMIVVYAVVLFSFSKYMVIFLISLSLALSIVMYPIIKISKNLIDKNIKEKVNVQNITS
                     EVISKNSDIKLTGEEEFWINKWDNFNTKQLIIGRKLDIHLSIVSSITNVLQIILPVLT
                     LIVGVNIKTFEQLTLGQIVAISTVSPYFISPII"
BASE COUNT         2162 a          712 c         1006 g         2124 t
ORIGIN      
        1 gataagacta tattcagaat atgccaaaaa ttcggaatgg tataaatttg cggagggttc
       61 atttgaaata tttagaaaac atccccaaag aattaatttt aagaaagatt tttctagaat
      121 tttggaaccc tttattatta atttgcttaa attaatcaat aattatctag agaataaaga
      181 atacgagtgg attgacaaga atggaaatat tttttcctct ctagtatttt atttagaaga
      241 tttaatctat ccttggattg ttaaaccttt ggttttagag ataaattcat tgcgtgaaaa
      301 aggtttactt gaaggggaat cggagcagca acggtacaaa tattttataa cattgtttga
      361 caaggaagag aatatattaa atttttataa caaatatccc gttttactga ggcaaatatc
      421 ggagtcttgt cttcggttct atacttattt tatagaaatt ttatcaaatt tagaaaatga
      481 ttttagtgtg ctagaagaag aattagggct aagggggaaa ttaaatgata taaaatttgg
      541 aaagggtgat acacacagcc aaggaaaaac tgttttgata ctcttctttg atgacgcgaa
      601 aattgtttac aagcctaaaa atttaataat caataactca ctaaatacta ttgctgagta
      661 tatccgaaag gttgatgaaa aaattaggat aagaatacct cgaactattg cttattcgga
      721 tcacagctat gaagaattta ttgattatct acctctagag caaaagaaaa atttacctga
      781 atattattat aattttggtg tgcttttagc atttatatat ttatttaatg ggagtgatat
      841 acattttgaa aatttaattt cctatggaga tatgcctgta ataatagact ttgaaacaat
      901 gttacagcaa cctctatttg atgataaaac tggtcagagt ttgctggata ccctgtttca
      961 cagggtgact cgaactttgc ttcttccaac agagggagta aaaagggagg atggtcttga
     1021 tgttgagatg agtgctctta caggaaattt taagaaggat gcttttaatg gtcaagtttt
     1081 aattaattta aatactgata aggtaaagtt tgatattggg aaaattgatt ttgaaggtgg
     1141 gaaaaacctg cctgttcggg atggtgatat agaatttgat aagtatataa aagatttcaa
     1201 aaaaggtttt agggattttt atctgatatt tgaagagtta aataaaacag aagaatttaa
     1261 aatgctatta aaagcaaact tgtatggttt aaagacaagg gtacttttta gagacacaaa
     1321 tagctatgct tcagtactat cttttttata tcatcctgat ttttatgaag aaatgttaga
     1381 tagagaaaaa gcattggaaa atctctggag caataagttt tctaatcaag gtattgtagc
     1441 aagcgaatgt gaacaaatga ggttattaga tattccgatt ttttatacag atacaaatat
     1501 caatgaaatc tacgatgatt ttggaaatca ttttatttcc ctacatcaat tttctggata
     1561 tgactatttt atgaaatatt tacctaataa taatttggaa aatttagaaa agcaacttga
     1621 tatcattgaa atttattttc caagctttga tcagcgaaaa aaaggatata aattaaactt
     1681 atctaataga aaaaaaactc ccaaatgaaa gtttagttac tattctgcat aatgaagtag
     1741 aaaatattgc agactctttg gttattaata atatttatga cgaatatcca atttggagta
     1801 tacctgttaa ttttaaaggt tctaaatggt gtcttgaaca aacgggtaat gatatgtata
     1861 ggggtagagc tggaatatta ctgtttatgt actatgtaaa attattgaaa gataaatcat
     1921 catatactca actgtacaat aaaatgttat ctgcaattcc gccatctgtt tctttatcta
     1981 agaccacatt tggtttaact ggggatatag gatatttcat tgttctatcc attatagagg
     2041 attacgatac aaatactctc gcatgcttaa attatataaa gagtgtttta actgagcttg
     2101 aaaagactga ttttgcaagt gtttcaaaca agtctgacta tattaatggt cttctacctt
     2161 taattaatac actggtaaga tattatagga gaggaataga gaaggaacgt gttctaaggc
     2221 tagtattaag tttaggtgat acgctatata atgatgtaag cgagagagat aatagtaatt
     2281 ttggatatag ttttggccat ggactatcag gtgtaatttt tacattaaaa aatatttata
     2341 aagtgacaag acttaaaaaa tataaagaat taattttaca actagttcct agggagaaaa
     2401 tcaaaattca ttctttgaag tggtgtagtg gagaatttgg gacattagtt aatcatcccc
     2461 aaagtgttcc agagggaatt gtagctagtt tagataatga tacattttgc catggaagta
     2521 tggccataat aaatttttac atcgactaca tgaaagaaat ggatactagt atggaattgg
     2581 agtctttatt gtgtagtgtt gtaatgaata aatcaaaaga aggagagtat cgtatcgtcc
     2641 aaacaagcaa tttcccagat ttttctttgt atacaggtgt gactggtatt gcttatactt
     2701 ttttaaggta tatcgcactg aatcagaatg acaaaaagat agttatcccc tcattacttg
     2761 aaatctagct taatttatag ttttgtttct aaaatagagg tgtccactca ttaagcaata
     2821 taaaaatacc aagattgact agtttaatat gtaattctat aaaatatttt taatagtgta
     2881 gcttttcatt gagataataa tataataaag aaaagttcta ttctaattgc taaacggctt
     2941 gaggtatatg ctactgttat agaaatgatt ttaaactaaa atcaaaatta ctccaaaaat
     3001 agtattgatt ttggtttaat acaaaacata tgtaataatg tgagtcaaca aaagtctgtt
     3061 tttgtaccat actatcttga aaaatctact aaattcaaat tgagaggatg aattaaaatg
     3121 aataaaatat ttatatatgc aggagtgcga aatcataact ctaagacttt agagtatact
     3181 aagagacttt caagtatcat ttctagtaga aataatgttg atatatcttt caggacacct
     3241 ttcaattcag agctagaaat atctaattct gattcagaag agttgtttaa gaaaggaatt
     3301 gataggcaaa gtaatgctga tgatggaggt gttataaaaa aagagttatt agagtctgat
     3361 attataatta tctcttctcc tgtatattta caaaacgtat ctgtggacac aaaaaacttt
     3421 attgaaagga ttggggggtg gagccatctt tttcgattag ctggaaagtt tgttgtaaca
     3481 ttagatgttg ctgagagtaa cggctctgat aatgtgtcag aatatcttag agatatattt
     3541 tcatatatgg gaggacagat attacaccaa gtttcaatta ccaattcact caaagatatt
     3601 gcagaggctc agttgatgga ggcaacttat aaaattgaag atgtacttga agggaaaatt
     3661 aagtacaaaa caacggatta tcaagaaaga gcttaccaga cattaaaatt aattttagaa
     3721 aattatgatt ccgaacattt tgagaagatg tattgggaga aaaaacgcct ttttgaagct
     3781 aatagtttag aggaatggta ttatgttgaa aatattaaat aactctgtca tatatttatg
     3841 tttgattccg ttattgttcc tattattgat aatttttcca aatgattcat taatctatta
     3901 ttttcgattg attttaattt cgttaatatc aattacatta catgaactag gtcatttttt
     3961 agtgggaaga tgtttatctt ataaactaga gatgcttgct actccctttt tcttctattt
     4021 cagaaaaaaa atatatttca aatttccagt gttattagca ttcggttatt gtcaaatgag
     4081 taatagaaac attactaatg aaaaaaatag tgataggaat ttggtgttct acttctttgg
     4141 gggaggtgga gctaacctaa ttgtcgcaat attagcactt ttgggatttg tgccgtacgc
     4201 atcagaattt tttattttga atataattct ttttctagtt acggtatgtt taccaattga
     4261 tggaacagat ggcaatgcta ttagagagat agttttgtat tcaaaagatt caaaaacata
     4321 tcagagattc tttgcgaaca gtctctataa taatccttat ataacaatcg acgattttgc
     4381 aaaattaacc tctaaagaaa aatctttttt ttcaaaattt gaaaaatgtt tgataaacct
     4441 ttactttgaa gtgaaaggtg aagggtcagc atttacaatt gctaatcatg aagtttttga
     4501 ttcaaatatt caggaaaata ttatccatga gtactataaa ttactacata aatcttctga
     4561 ttggattatt ccacagaact tatctttaga agaagttgtt tttaccttgt caaactatat
     4621 ttactcgaaa aataataaat atttagaaaa gattaagtat ctaaagaaat tagtagattt
     4681 tagacaagaa gaaattatcg actttatttt gaacaaggag gaagtattgt gaaaattcca
     4741 atgatatatc aaatggaaaa ttcagaatgt ggattagcat gctgtgccat gatattgaac
     4801 tattttaaat atgagatttc tttaaatgaa ctacgtgaaa tctacccatc atccagatct
     4861 ggatattctc tcctatctat aagtaaagtt ttaggagatt ttaatataag ttctcatgct
     4921 tttaaagctt cggtaagaga tttaaaaccg ctcagtttcc cactcatttg cttctgggag
     4981 agttctcatt ttattattct tgaaaaaatt agtaaaaaca agttttatat tttagatcct
     5041 gcaaaaggca ggcagagaat gtcaataagt gaatttgaaa ggcattattc aaatatcatt
     5101 ttaacattta aaaagttaga tagctttatg tctcgtaaag ataataagaa gtcgcctgtt
     5161 ttaaagtatt tttttaagta taggaataag ctagggattt tattttttgt aacagcatta
     5221 ttgtatgtaa tacaatcatt agtacctata gctaatagat acataattga cacgaatttc
     5281 aaggacgatt cgtattcgtc tagaatgtta tttactatat tatttatatt tactgtttca
     5341 ttctcactaa tgtatttatt aagacagata tatgttgcat ccttaaaata tataatggat
     5401 aaagagatta gctatgattt tatgaaacat ttgatatatt taccttacag tttttatgaa
     5461 aaacgtactt taggggatat actttttaga gctaactcta ttgtttatat aagagaaata
     5521 ctatcaaata attttatagc agctatactt gatttgttaa tgattgtggt ttatgctgtg
     5581 gttttattta gcttttctaa gtacatggta atctttttaa tatcactaag tctagctcta
     5641 tctattgtaa tgtatccaat cataaaaatc tcaaaaaatt taattgataa aaatataaaa
     5701 gaaaaggtta atgttcaaaa tattacttcc gaagtaattt ctaaaaatag tgatattaag
     5761 ctaactggag aagaggaatt ttggattaac aaatgggata attttaatac aaaacagctc
     5821 atcataggtc gaaaacttga tatacattta tcaattgtta gtagtataac gaatgtttta
     5881 caaattattc tccctgtttt gacccttatt gtaggtgtaa atataaaaac attcgaacaa
     5941 ttgacgttag gacaaattgt agcaataagt acagtctcac catactttat ttctcctata
     6001 attt
//
LOCUS       DAVKEV010000080         5939 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVKEV010000080 DAVKEV010000000
VERSION     DAVKEV010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5939
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.080"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            411..632
                     /locus_tag="VWZ68_002015"
                     /pseudo
     CDS             411..632
                     /locus_tag="VWZ68_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(919..1401)
                     /locus_tag="VWZ68_002016"
     CDS             complement(919..1401)
                     /locus_tag="VWZ68_002016"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEU9372983.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(1496..2980)
                     /locus_tag="VWZ68_002017"
     CDS             complement(1496..2980)
                     /locus_tag="VWZ68_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEU9372984.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQLAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3133..4740
                     /locus_tag="VWZ68_002018"
     CDS             3133..4740
                     /locus_tag="VWZ68_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEU9372985.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDELIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            4905..5072
                     /locus_tag="VWZ68_002019"
     CDS             4905..5072
                     /locus_tag="VWZ68_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEU9372986.1"
                     /translation="MKKRILSAGLTFTSALLLAACDQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(5065..5586)
                     /locus_tag="VWZ68_002020"
                     /pseudo
     CDS             complement(5065..5586)
                     /locus_tag="VWZ68_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1752 a         1117 c         1322 g         1748 t
ORIGIN      
        1 aactggttcc ttttgaggta cgacgggcat gtcgtatagt aggttgaaac tagaatagta
       61 cacatctact tctaaaacat ttttagaaat cgatttgact gtcctgatcg atttgtcctg
      121 ttcttatttc attttactat atatctgagg tgtaagtcct cggtgggcac ctgttaccgg
      181 tgaacccaat agcgattccc aagcctgact atcgtgaggt agcggattaa aacggtctgg
      241 ggatagaccg ttttaagtct gacgctggaa ataagaatcg tcagaggaag ggatagcgaa
      301 ctcgtggctc tacgaacagg aacgtgatag taaggcgtat atagcggata agggggcctc
      361 aaactctaaa gtccaaaaag gtagtcgtaa cctatatgcg taaatcacga gagcaactga
      421 atttgtccat tcgaggatgg ataaactatt tttcattggg aaatatgaaa agtatagtca
      481 ccagcataga tgagcgtttg catactcgcc tacgagtgat tatctggaag caatggaaga
      541 agaaatcgag acgattatgg ggattgctta agttaggggt tcctaaatgg atagcagata
      601 aggtatctgg ctggggcgac cactatcaat tatagtaaaa tgaaataaga atagaacaaa
      661 tcgatcagga tagtcaaatc gatttctaac aatgttttag aagcagaggt gaactattct
      721 agtttcaatc cactatagta gctcagaagt cggtacttaa acgtgctata tcaaaaccag
      781 tccttgaaaa acgtggattg gtttcgtgtt tggattatta ccttgaacga catgcgttaa
      841 aaagttagtt gaaccgccgt atgccgaacg gtacgtacgg tggtgtgaga ggggctagag
      901 attatcccct actcgatttt aaatcacatg acgttcaaag gcatcatctg aaatcccttg
      961 ttccaagatg agttttgccc attctttagc agagaagagg ctgtggtcct tgtagtttcc
     1021 gcaagattcg atggttgtcc ctgggacatc ttcccaagta gtagtttcag cgatttcctt
     1081 gagcgaatcc ttgataacag ctgcgatttt agcactggtg tgacgtcccc acataatcat
     1141 gtggaagcct gtgcggcaac caaatggtga acagtcaatc atgccgtcaa tgcgggtacg
     1201 gatgagtttg gctaagaggt gctcgatagt gtgaaggccg gcagtaggga tagagtcttc
     1261 gtttggttgc accaagcgaa tatcataatt ggagatgatg tctccttttg gtcctgtttc
     1321 ttccccaatc aagcgaacat agggtgcttt gacaatggtg tggtcaagtt caaaactttc
     1381 gacaataact tcttttgaca tggtaaatcc tttcagtttt cttctctcat tatatcataa
     1441 aggttgctcc tgagacagag agaaaacctc tccgaggctg gagaggttga aatctttact
     1501 tacgatataa gcggtcgtat tggtagtatg ggtcaaaggt tacgttgata cccagtttac
     1561 gaaggacatt cttgtcttca tcagtcaaga tgatggttga gtgggcttcg cttcctttga
     1621 ggttgccgag ttcttccata gcgcgggcag catcaggatt ttctgtagct gtgatagcaa
     1681 gtgcaatcag gatttcattt gaatgaaggc gtggattgcg gctaccgaga tgatcgattt
     1741 taagaccttg gattggctta acaacttcag gctcgattag ttttacttct ttagcgatgt
     1801 cagctgattt tttgatggcg ttgatcaagg cagcggctgt aggcccaaag agttctgagt
     1861 tcttaccagt gacgatttcc ccatttggca attcaaaggc tagggctggt ccaccagttt
     1921 cttctgcttt ttggcgcgca acgacagcaa ccttacggtc tgcaggtgtg ataccgaggt
     1981 cgttcatgag caactcaatt ttcttgacgg cagcttcgcc aactttttca gctttgaagt
     2041 caagaactgt ttgatagtaa cggcggatga tttcttgttt agaagcttcg acagcagcct
     2101 cgtcatctgt aatagcgaaa ccaaccatgt tgacacccat atctgtcggt gaagcgtatg
     2161 gtgattttcc gagaatacgt tccaacatgc gcttgagcac tgggaagatt tcgatatcac
     2221 ggttgtagtt gacagtggtt tctccatagg tttgaagatg gaaggggtca atcatgttga
     2281 catcatcaag gtcagctgtg gcagcttcat aagccaagtt aactggatga tgaaggggaa
     2341 gattccaaac agggaaggtt tcaaatttag cgtagccaga cttgatgcca ttgatttggt
     2401 cgtggtacat attggacata cacgttgcca attttccaga accgggtcca ggagcggtta
     2461 cgacaatcaa gttgcgactg gttttgatgt agtcgttttt gcccatgcct tctggggaaa
     2521 tgatgtgatc catatccgtc ggatatcctt tgattggata atgaagataa gaatcaattc
     2581 cgtttttctc aagttggttg cggaaggcat ctgcagcgag ttggccagcg tattgtgtaa
     2641 tgacaacgga accaacaaaa atccctaatt cattgaattt gtcaatcaaa cgaagaactt
     2701 cttggtcata agaaatgcct aagtcgccac gtgctttgga atgttcaatg ttgctagcat
     2761 taatggcaat cacaacctca acctgctctt tcaattcttg caagagcttg attttgttgt
     2821 caggttcata accaggaagg acacgagcag cgtggaaatc ttctaacatt ttaccgccaa
     2881 actctaagta gagcttgccg tcaaattggt taatgcgctc taagatgtgg tcgcgttgta
     2941 aattcaaata ctgttcagaa ctaaaagctt gttttttcat ttttttacct ctggattcta
     3001 ttataataaa aaattggaag ttaggaaact acggagctaa aaaagaaatt aaaaagatta
     3061 agcaaacgct tgcacaaaat tttaaaaagt gctatcatat actatagatt attaaaataa
     3121 tgaggtaaac agatgcaaga aaaatggtgg cataatgccg tagtctatca agtctatcca
     3181 aagagtttta tggatagtaa tggagatgga gttggtgatt tgccaggtat taccagtaag
     3241 ttggactatc tagctaagct aggaatcaca gcgatttggc tttctcccgt ttatgacagc
     3301 cctatggatg ataatggcta tgatattgct gattatcaag cgattgcggc tatttttgga
     3361 accatggagg acatggatga actgattgca gaagctaaga agcgtgatat ccgtatcatc
     3421 atggacttgg tggtcaatca tacctcggat gagcatgcct ggtttgtaga ggcctgtgaa
     3481 aatcctaata gccctgagcg agactactat atctggcggg atgagcctaa cgatttagat
     3541 tctatcttta gtgggtctgc ttgggaatac gatgaaaagt caggtcaata ctatctccac
     3601 tttttcagca agaaacagcc ggatctcaac tgggaaaatg aaaaacttcg ccagaaaatt
     3661 tatgagatga tgaacttctg gattgataag ggtattggtg gtttccgtat ggatgttatt
     3721 gacatgattg gcaaaattcc tgacgagaag gtagtcaata atggtcctat gctccatccc
     3781 tatctcaagg aaatgaatca ggcgaccttt ggagataagg atctcttgac agtaggggag
     3841 acttggggag caacgccaga gattgccaaa ctctactctg atccaaaggg gcaagaattg
     3901 tctatggtct tccagtttga acatatcggt cttcagtatc aggaaggtca acctaaatgg
     3961 cactatcaaa aagagctgaa tatcgctaag ttaaaagaaa tcttcaacaa atggcagaca
     4021 gagttaggag ttgaggacgg ctggaattcc ctcttctgga acaaccatga cctccctcgt
     4081 attgtctcaa tctggggaaa tgaccaagaa taccgcgaaa aatctgccaa agcctttgca
     4141 atcttacttc atctcatgag aggaactcct tatatctacc aaggtgagga gattgggatg
     4201 accaactatc cgtttgaaac actggatcaa gtagaagata ttgaatctct caactatgcg
     4261 cgtgaggctc ttgaaaaagg tgttccgatt gaagaaatca tggacagtat ccgtgttatt
     4321 ggacgtgaca atgcccgtac ccctatgcaa tgggacgaga gcaaaaacgc tggtttctca
     4381 acaggtcaac cttggttggc agttaatcca aattacgaga tgatcaacgt ccaagaagcg
     4441 ctggcaaatc cagattctat tttctatacc tatcagaaac tggtccaaat tcgcaaggag
     4501 aatagctggc taattcgagc tgactttgaa ttgcttgata cggctgataa ggtctttgct
     4561 tatatacgta aggatggcga ccgtcgcttc ctagttgtgg ctaacttgtc caatgaagag
     4621 caagacttga cagtagaagg aaaagtcaaa tctgtcttga ttgaaaacac cctagctcaa
     4681 gaagtctttg aaaaacaaat cttagttcca tgggatgctt tctgtgtgga attactataa
     4741 atattttttg cagaaaaatt taaaattgaa atcgtataaa aacaagggag gactgtataa
     4801 aaggcagaaa tcctttgttt tttataacca aggtttataa accttcattc tcgaaattca
     4861 attaacttta caaattccca ctattaagga gaaagaagac gaacataaag aagcgtatcc
     4921 ttagtgcagg cctgactttt acatctgctt tgcttttagc tgcttgcgac caatcaggtt
     4981 cagatacaaa aacttactca tcaaccttta gtggaaatcc aactacattt aactatctat
     5041 tagactatta cgctgataat atagtcaatt gaaacaagaa caagacaaaa gagcctcata
     5101 aaaggtattg caacttggta ataccttttt gaggtgcttt ttgatatgag cccatgtttt
     5161 ctcaatagga ttgtactcag gtgagtaggg aggaagaggt aaaagtttat gcccaaactc
     5221 ttcgcataaa agttctagct tccccattct atggaatctt gcattatcca taataataac
     5281 cgatggtgtg gttaatgttg gtaagaaaaa cttctgaaac catacttcaa aaaagtcgct
     5341 cgtcatcatc tcttcgtaag tcattggagc gattaattca ccatttgtta gacctgcaac
     5401 caaagaaatc ctctgatatc ttcttccaga tactttgcct cttcttaact gaccttttaa
     5461 tgagcgacca tattctcgat aaaaataagt atcgaatcct gtttcatcaa tctaaacagg
     5521 tgctaggtgc tttaaactat taaaattctt aagaaataag gctacttttt ctgggtcttg
     5581 ttcataatta gattgaaact agagtagtag acctctgctt ctaaaacatt gttagaaatc
     5641 gatttgactg tcctgatcga tttgtcatgt tcttatttca ttttactata tttttgtttc
     5701 gcgggaagtc tactaagata cttaaagatg cagatagtaa aaaaaatgtg tcaatcgaaa
     5761 gtgattatgt ccccaaaaaa tggagagttt gagggcaatt attttgattt catttgacac
     5821 gaggaaccct tgaagctgtt ttgttagcta aaccaaggct agtcttagcc ttggctcgcc
     5881 agcctaacag ctccaagcct cttatcaaat gaaatacttg tcttacactc ctcactttc
//
LOCUS       DAVKEV010000081         5905 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVKEV010000081 DAVKEV010000000
VERSION     DAVKEV010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5905
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.081"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            109..1809
                     /locus_tag="VWZ68_002021"
     CDS             109..1809
                     /locus_tag="VWZ68_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEU9372987.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            1802..2278
                     /gene="ilvN"
                     /locus_tag="VWZ68_002022"
     CDS             1802..2278
                     /gene="ilvN"
                     /locus_tag="VWZ68_002022"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEU9372988.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            2344..3366
                     /gene="ilvC"
                     /locus_tag="VWZ68_002023"
     CDS             2344..3366
                     /gene="ilvC"
                     /locus_tag="VWZ68_002023"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU9372989.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            3473..3709
                     /locus_tag="VWZ68_002024"
     CDS             3473..3709
                     /locus_tag="VWZ68_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9372990.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMNFEQFFKLAQI
                     SREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            3947..4303
                     /locus_tag="VWZ68_002025"
     CDS             3947..4303
                     /locus_tag="VWZ68_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU9372991.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            4353..5603
                     /gene="ilvA"
                     /locus_tag="VWZ68_002026"
     CDS             4353..5603
                     /gene="ilvA"
                     /locus_tag="VWZ68_002026"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEU9372992.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
BASE COUNT         1822 a         1002 c         1348 g         1733 t
ORIGIN      
        1 taaacgttaa aatagaaaat tcagaaaatt tcttctttta tcttgaaaaa ttttgaaaaa
       61 atggtatgat agtaacaagt tatttttaag aggaaagaaa ggggaacaat ggagaaaatc
      121 agtttagaat ctcctaagac ggggtcggac ctagttttgg aaacacttcg tgatttagga
      181 gttgatacca tctttggtta tcctggtggt gcggttttgc ctttttatga tgcgatatat
      241 aattttaaag gcattcgcca cattctaggg cgccatgagc aaggttgttt gcatgaagct
      301 gaaggttatg ccaaatcaac tggaaagttg ggtgttgccg tcgtcactag tggaccagga
      361 gcaacaaatg ccattacagg gattgcggat gccatgagcg atagcgttcc ccttttggtc
      421 tttacaggtc aggtggcgcg agcagggatt gggaaggatg cctttcagga ggcagacatc
      481 gtgggaatta ccatgccaat cactaagtac aattaccaag ttcgtgagac agctgatatt
      541 ccgcgtatca ttacggaagc tgtccatatc gcaactacag gccgtccagg gccagttgta
      601 attgacctac caaaagatat atctgcttta gaaacagact tcatttattc accagaagtg
      661 aatttaccaa gttatcagcc gactcttgag ccgaatgata tgcaaatcaa gaaaatcttg
      721 aagcaattgt ccaaggctaa aaagccagtc ttgttagctg gtggtggaat tagttatgct
      781 gaggctgcta cggaactaaa tgaatttgca gaacgctatc aaattccagt ggtaaccagt
      841 cttttgggac aaggaacgat tgcaacgagt cacccactct ttcttggaat gggaggcatg
      901 cacgggtcat tcgcagcaaa tattgccatg acggaagcgg actttatgat tagtattggt
      961 tctcgtttcg atgaccgttt gacggggaat cctaagactt tcgctaagaa tgctaaggtt
     1021 gcccacattg atattgaccc agctgagatt ggcaagatta tcagtgcaga cattcctgta
     1081 gttggagatg ctaagaaggc cttgcaaatg ttgctagcag aaccaacagt tcacaacaac
     1141 actgaaaagt ggattgagaa agtcactaaa gacaagaatc gtgttcgttc ttatgacaag
     1201 aaagagcgtg tggttcaacc gcaagcagtt attgaacgaa ttggtgaatt gacgaatgga
     1261 gatgccattg tggtaacaga cgttggtcaa caccaaatgt ggacagctca gtattatccc
     1321 taccaaaatg aacgtcagtt agtgacttca ggtggtttgg gaacaatggg ctttggaatt
     1381 ccagcagcaa tcggtgctaa aattgctaac ccagataagg aagtagtctt gtttgttggg
     1441 gatggtggtt tccaaatgac caaccaggag ttggctattt tgaatattta caaggtgcca
     1501 atcaaggtgg ttatgctgaa caatcattca cttggaatgg ttcgccagtg gcaggaatcc
     1561 ttctatgaag gcagaacatc agagtcggtc tttgataccc ttcctgattt ccaattgatg
     1621 gcgcaggctt atggtattaa aaactataag tttgataatc ctgagacctt ggctcaagac
     1681 cttgaagtca tcactgagga tgttcctatg ctaattgagg tagatatttc tcgtaaggaa
     1741 caggtgttac caatggtacc ggctggtaag agtaatcatg agatgttggg ggtgcagttc
     1801 catgcgtaga atgttaacag caaaactaca aaatcgttca ggagtcctca atcgctttac
     1861 aggtgtccta tctcgtcgtc aggttaatat tgaaagcatc tctgttggag caacagaaga
     1921 tccgaatgta tcgcgtatca ctattattat tgatgttgct tctcatgatg aagtggagca
     1981 aatcatcaaa cagctcaatc gtcagattga tgtgattcgc attcgagata ttacagacaa
     2041 gcctcatttg gagcgcgagg tgattttggt taagatgtca gcgccagctg agaagagagc
     2101 tgagatttta gcgattattc aacctttccg tgcaacagtg gtagacgtag cgccaagctc
     2161 gattaccatt cagatgacgg gaaatgcaga aaagagcgaa gccctattgc gagtcattcg
     2221 cccatacggt attcgcaata ttgctcgaac gggtgcaact ggatttaccc gcgattaaaa
     2281 atccaactta aatttattaa accagcctaa aaggcaataa ataatagaaa agagagaaaa
     2341 gctatgacag ttcaaatgga atatgaaaaa gatgttaaag tagcagcact tgacggtaaa
     2401 aaaatcgccg ttatcggtta tggttcacaa ggacatgcgc atgctcaaaa cttgcgtgat
     2461 tcaggtcgtg acgttattat cggtgtacgt ccaggtaaat cttttgataa agcaaaagaa
     2521 gatggatttg atacttacac agtagcagaa gctactaagt tggctgatgt tatcatgatc
     2581 ttggcgccag acgaaattca acaagaattg tacgaagcag aaatcgctcc aaacttggaa
     2641 gctggaaacg cagttggatt tgcccatggt ttcaacatcc actttgaatt tatcaaagtt
     2701 cctgcggatg tagatgtctt catgtgtgct cctaaaggac caggacactt ggtacgtcgt
     2761 acttacgaag aaggatttgg tgttccagct ctttatgcag tataccaaga tgcaacagga
     2821 aatgctaaaa acattgctat ggactggtgt aaaggtgttg gagcggctcg tgtaggtctt
     2881 cttgaaacaa cttacaaaga agaaactgaa gaagatttgt ttggtgaaca agctgtactt
     2941 tgtggtggtt tgactgccct tatcgaagca ggtttcgaag tcttgacaga agcaggttac
     3001 gctccagaat tggcttactt tgaagttctt cacgaaatga aattgatcgt tgacttgatc
     3061 tacgaaggtg gattcaagaa aatgcgtcaa tctatttcaa acactgctga atacggtgac
     3121 tatgtatcag gtccacgtgt aatcactgaa caagttaaag aaaatatgaa ggctgtcttg
     3181 gcagacatcc aaaatggtaa atttgcaaat gactttgtaa atgactataa agctggacgt
     3241 ccaaaattga ctgcttaccg tgaacaagca gctaaccttg aaattgaaaa agttggtgca
     3301 gaattgcgta aagcaatgcc attcgttggt aaaaacgacg atgatgcatt caaaatctat
     3361 aactaattag aaatatatag cgctggagat gattttatga aaaagattat gagaaaaact
     3421 gcatcgttat tattggttct agttgtataa tgtaattaca ccgtcggtaa tagtgctagc
     3481 agaccaaaat aaagcagatt ggtcgtatga tgaaaatgct gtaattaaca tttatgatga
     3541 tgctaatttt gaagatggta ggttgcatat gaactttgaa caattcttca aattggcaca
     3601 aatatctaga gaagaaggtc ttgaaattca ttctccgttt gagagagctg gtgcgactaa
     3661 atctgctcgt tatatagcga aatggatttt gagaaataaa aaacattaac aaatatagtt
     3721 ggtaaatcat taggacctaa atcagctgtt agattcggag aagctttatc ctatattgaa
     3781 ggtcctcttc gcagaataaa tgagacgata gatggcggtt tatatcaaat agagcaaatt
     3841 attgcatctg gattgaaaga atcgggttta aatgactgga ctgcgaaaac tttagcttca
     3901 gctattcgtg ggatattaga tgtacttatt taggggttga aatcatatga atattaccaa
     3961 tttgttttct atcaagacag gatgtgatga aactgatagg caactgcaaa aactattttt
     4021 tcagttggat ttacaattgg gagaattgac agatcaacta agaaaattag attctaattt
     4081 tgttcctcgt agtcaatttg tagacacgtt ggatttgaat gatgtagaat ataaagaaat
     4141 tttaaactat tttatcttcc atcgtaatga tagtgaagaa agtttggtag aatggttata
     4201 tgattggatt tccacaaatc gttatgaact tcctaaagag ttttcgattc gtatggctca
     4261 taaataccat gaaagtgtta ctgaagtttt cggagatgaa taactaaaaa acagtcatta
     4321 gtgactgttt tttatagaaa aagaggtttt atatgttaag ttcaaaagat ataatcaagg
     4381 ctcacaaggt cttgaacggt gtggttgtga atactccact ggattacgat cattatttat
     4441 cggagaagta tggtgctaag atttatttga aaaaagaaaa tgcccagcgt gttcgctcct
     4501 ttaaaattcg tggtgcctat tatgccattt cccagctcag caaggaagaa cgtgaacgtg
     4561 gggtagtctg cgcttctgcg ggaaatcatg cgcagggagt agcctatact tgtaatgaaa
     4621 tgaaaattcc tgctactatc tttatgccca ttactacgcc acaacaaaag attggtcagg
     4681 ttcgcttttt tggtggggat tttgtaacta ttaaactagt tggagatacc tttgatgcct
     4741 cagccaaagc agctcaagaa tttacagtct ctgaaaatcg tacctttatt gatccttttg
     4801 atgatgctca tgttcaagca ggtcaaggaa cagttgctta tgagatttta gaagaagctc
     4861 gaaaagaatc gattgatttt gatgctgtct tggttcctgt tggtggtggc ggtctcattg
     4921 ccggggtttc tacctatatc aaggaaacaa gtccagagat tgaggttatc ggagtagagg
     4981 cgaatggagc gcgttccatg aaagctgcct ttgaggctgg aggtccagtc aaactcaagg
     5041 aaattgataa atttgcggat gggattgctg tgcaaaaggt aggtcagttg acctatgaag
     5101 caactcgtca acatattcaa actttggtag gtgtcgatga gggattgatt tctgaaacct
     5161 tgattgacct ttactctaag caagggatag tcgcagaacc tgctggagca gctagtatcg
     5221 cctctttaga ggttttagct gaatatatta aggggaaaac catttgttgt atcatttctg
     5281 gaggaaataa tgatatcaac cgtatgccag aaatggaaga gcgtgccttg atttatgatg
     5341 gtatcaaaca ttactttgtg gtcaatttcc cacaacgtcc aggagctttg cgtgagtttg
     5401 taaatgatat cctggggcca aatgatgata tcacacgttt tgagtatatc aaacgagcta
     5461 gcaagggaac aggcccagta ttaattggga tcgctttagc agataagcat gattatgcag
     5521 gtttgattcg tagaatggaa ggttttgatc cagcttatat taacttaaat ggtaatgaaa
     5581 cgctttataa tatgcttgtc tgaggactaa taaaaaaata tcatattatt tgtacaactg
     5641 atgtatatgt gctataatga agatgaagaa aggggacgat tcctatggtt ttagaaaact
     5701 tatcgtgcaa ttcttacttc tgttcattat agcacttatg atgtttggct cagatttcca
     5761 tccttcattt tgatttccta tctattgaca agcatagtca cactgtcttt aatactcttc
     5821 gaaaatctct tcaaaccacg ttagctctat ctgcaacctc aaaacagtgt tttgagcaac
     5881 ttgcggctag cttcctagtt tgctc
//
LOCUS       DAVKEV010000082         5208 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVKEV010000082 DAVKEV010000000
VERSION     DAVKEV010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5208
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.082"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(434..1162)
                     /locus_tag="VWZ68_002027"
     CDS             complement(434..1162)
                     /locus_tag="VWZ68_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9372993.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1320..2729
                     /locus_tag="VWZ68_002028"
     CDS             1320..2729
                     /locus_tag="VWZ68_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU9372994.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWLERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2747..4042
                     /locus_tag="VWZ68_002029"
     CDS             2747..4042
                     /locus_tag="VWZ68_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9372995.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            4047..4355
                     /locus_tag="VWZ68_002030"
     CDS             4047..4355
                     /locus_tag="VWZ68_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9372996.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4352..4660
                     /locus_tag="VWZ68_002031"
     CDS             4352..4660
                     /locus_tag="VWZ68_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9372997.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEVHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1772 a          866 c          938 g         1632 t
ORIGIN      
        1 aaaataaaat ttttttaaat gattatgatt cagaatttat ttaatatatt aaaagaagat
       61 atgaacaaat aaattgggag attgaaattc atttctagca atttgttaga agtcacagtc
      121 tactattcta acatcagtat actatatgtg ttacaagaaa agactcaaaa acttctcgtc
      181 agtgtaagaa tatttgaaac actatttaaa actaaataac tataagaagt agatcaggtg
      241 aacaatttca gtacctactc tataagctat acgaagatat ttttcaacat gatggataaa
      301 acgatcactc ttttaaagcc atcttattta gaaaagagaa accatttaag catagatggg
      361 accttcttgc cctgttttaa atttttctta aactagagtc tgtaaaagat tggcttcatt
      421 ttcacatttt ctcctaggag gaatgtcgta atgcaaaaga attaaattca aataaatcat
      481 agcgatgacg actaatcgag tactcaaacg gagttccgtt atccaaataa gccacttgtt
      541 ctacttcaaa taccggttcc gttggaagga gctgcaagta atgttgctca ttttctgaac
      601 tagaagaagc tcgcaagatt tttgtagcac tggcaatatg caatcctaac tttccttcaa
      661 tgtaattgta aatcgatttt tgtaaaatat cttcagtaat acctggaata acatcagtac
      721 tcatataagt ttgttccaga acataaggtt taccgtcaat aatacgcaga cggtaaatat
      781 tataaactgg actctgcaaa gcgacctgta gtttttctgc taaaaattca tttgcaaatt
      841 ctaatttgaa gtgaataatc ctcgagtcaa ttgtagaatg agcatcttca gatatttttg
      901 tcagtccccg gatatctctt tctggaacga ttaattttct ttttgagctg ccacgagaga
      961 gaacaaaggt tccctgccca cgttttctaa aaattaagcc ctcagaaact aacaagtcta
     1021 aagctttttt gatcgtcatt cgactacagg caaactgttt agctaatgtc atttcatcag
     1081 gcaattgttc gttcatggta tatttattac aaagaatctt ttcacgaatc tcattgtaaa
     1141 taaataaata ttttgtactc atttaatctg gttctctcta taatattcta atagtagtat
     1201 aacaaagttc aagaaatgag gcaaacacaa gatatgtatc aacaattttt aaaaatgtct
     1261 agacaaattt taaaattatg ctatacttta tgtatagaat aatagaaagg aggttgagca
     1321 tgaaaaaaaa gttagtattt cctaatctat tttggtgggg agctgcttct agcggacctc
     1381 agacagaagg tcaatatgga aaagtacatg aaaatgtgat ggactactgg ttcaaaacgc
     1441 atccagaaga ttttttcgat aatgtcggac ctcttgtagc cagtaacttt tttcatactt
     1501 acaccgaaga tttccacttg atgaaggaaa ttggagttaa ttctttccgc acttccatcc
     1561 aatggagtcg actcatcaag aatttagaga caggtgagcc tgatccaaaa ggtattgctt
     1621 tctacaatgc catcattgaa gaagctaaaa agaaccagat ggatcttgtg atgaatttac
     1681 atcattttga tttaccagtg gaacttcttc aaaaatacgg tggttgggaa agcaaacatg
     1741 tagtggagtt attcgtgaag tttgccaaga ctgctttcac atgctttgga gataaggttc
     1801 attactggac aactttcaat gagccaatgg tcattccaga agcaggatac ttatatgctt
     1861 tccattatcc aaatctaaaa ggaaagggaa aagaggccgt acaagtcatc tataatctaa
     1921 accttgctag tgcaaaagtg attcaactat atcgctcatt agaacttgat ggaaagattg
     1981 ggattatttt aaacttgaca cctgcttatc caagaagtaa ttctccagaa gacttagaag
     2041 caagtcgatt tacagatgac ttctttaaca aagtcttctt gaatccagct gttaaaggaa
     2101 ctttcccaga aagattggta aaacagctag agagagatgg cgtgttatgg agtcataccg
     2161 aaaaagagct tcaactgatg aaatcaaata cggttgattt tcttggagta aactactacc
     2221 atccaaaacg tgttcaagca caagcaaatc ctgaagaata tcagacgccc tggatgccag
     2281 accaatactt caaagagtat gaatggctgg agcgtcgcat gaatccatat cgtggttggg
     2341 aaatttttcc gaaagccatt tatgatattg ctatgattgt gaaggaagaa tatggtaata
     2401 tcccatggtt tatcagtgaa aacggaatgg gtgttgaaaa cgaagcacgg tttatcgatg
     2461 aaaatggagt tatcgatgac gtgtatcgta ttgaatttta tgaagaacat ttaagatggc
     2521 tacataaagc cattgaagag ggaagtcact gttttggata ccacgcttgg accgcatttg
     2581 attgctggtc ttggaataat gcatataaga atcgttacgg atttatctcc gttgatttag
     2641 aaacgcaaaa gagaaccatc aagagctcag gaagatggta tcgcaaagta agtgacaata
     2701 acggttttga agtagaaatt gaggagtaaa gagaggagat attcatatga aaaactcaaa
     2761 atttatagac caatttgcca cctttgctgg taaactaggg aaccaaattc atttaaaaac
     2821 cctaagagat gcattcgtaa cagtaatgcc attatatatt ttggcaggtt taatcgttct
     2881 tttgaacaac acggtattta agtggatttt ccaaggggat acattaacaa gattccaata
     2941 ttggggaata acaattgcaa acggtacttt aagtatttca ggtatgatta ttgctgtaat
     3001 ggttggttat ttcttagcta aaaacagaga tttcgaaaac ccgttagcag catcaatgct
     3061 atcattagtt tctttaattg tgatgatgcc aaatacagtt tctgtagttc ctgacggagc
     3121 aaaagatgcg gtaaacattt caggtgttct ttcattcaac aacacaggta caggcgcaat
     3181 gttcgccggg gttatcgtag cgattattgc aacagaatta ttcattgaat tatcaaacgt
     3241 taaagcttta caaatgaacc ttggtgaaaa tattccacca gctgttagta gatcatttag
     3301 cgtattactt ccagtcatga ccgtcatctc cttatttggg gttgtttcag cattattatt
     3361 caatataact ggaatgaact taatctcaat cattacaatc tttattcaag aaccaattcg
     3421 tcatattggt acaagcttaa tcggggtcat tattatttac tctttaggaa atatgttatg
     3481 gctatttggt attcaccaag cagttattta cagtgccatc ctagaaccat tactattaat
     3541 taacattact gaaaacatca ctgcagcaaa taatggacaa gccattccac acatcatcaa
     3601 cctatcacaa atacaaacat tcgctttaat gggtggtagt ggatctacat tatgtttatt
     3661 aatagcaaca ttcttagtga gtcgcaatgc tgtctctaaa aacgtggcta aattatcttt
     3721 tggacctggt atcttcaata tcaatgaacc agtattattc ggttacccaa tcgtttataa
     3781 catttcatta gctattccat ttatcacagt tccagtcctt ggtattttaa tcagctactt
     3841 agcaacagtt acaggattca tgagtcctgc atttatacaa gttccttgga ctacaccagt
     3901 attcttaaat gcatggttag caacagcagg ggacgtgaga gcagttctag ttcaattcat
     3961 catctttgca cttggagttc ttctatacat tccatttatc aaagttaatg acaaagttgt
     4021 tgaacaagaa atggaaggtt aagattatga aacaaatttt attagtatgt aatgcgggaa
     4081 tgtcgacaag tatgcttgtt aaaaaaatgc aacaaagtgc gactgaacgt gggattgaaa
     4141 tttctatcca agcaaaatca atgacagagg cgaaaaagaa tatccatgaa gcagatgtca
     4201 ttctaattgg gccacaaatt cgttatgagt tacttgctgt gaaagaaatt gcaggaaata
     4261 tccctgtaga taccattgat atgcgggatt acggaatgat gaatggagca aaagttctgg
     4321 aacaagcact tgcatggata ggagaaataa gatgacagaa gaaatggaat atatctgttt
     4381 tcagctcatt gccaatagtg gagcagccaa atcatccttt attgaagcca tccaactagc
     4441 taaggcagga aatttaaaag aagcgaaaat taaagttgaa gaagcggaag actccttagt
     4501 agaagtgcac aagattcact ctaatctcat acaaaaagaa gctactggag aaaaaatagg
     4561 attctccttg ctatttatgc atgcagaaga ccaaatggct tcaacggaga ttattcagtt
     4621 gctatctaaa gaattcatcg atctctatca aaataaatag gaacactgtc gttcccatct
     4681 gtctttatta atgacggcta cattgtagga acctccaaaa gttggacaaa atgattgaaa
     4741 ggattggatc ctgcattaca caagatccaa tccttttctt ttactctagt ttttataata
     4801 tgttgaatct agaatagtcc actgtagttt ctaaaaaatt gctggaaatg gatgttaagc
     4861 tccaatttat ttgtttatat cttatttcag tttactatac tagcttatta ttctagtgaa
     4921 aaattgaatg agccactatt tatttaatat gtatgatgag ggaatgactc aaaaacttct
     4981 tgtcgatata agaatatctg agatagtatt ttaaaacgaa aggattataa aagctcattt
     5041 ccttcgcact tattttatag agatctatca ttatactctt tagaaatcaa aaagcaacac
     5101 accttgtcat cgttttctcg tttgctcttt gattttaatt gggccttagt aaatactact
     5161 cttaaattaa actatagtga attgaaataa gatgtgaaca actctatc
//
LOCUS       DAVKEV010000083         5188 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVKEV010000083 DAVKEV010000000
VERSION     DAVKEV010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5188
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.083"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            109..504
                     /locus_tag="VWZ68_002032"
     CDS             109..504
                     /locus_tag="VWZ68_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEU9372998.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            515..886
                     /locus_tag="VWZ68_002033"
     CDS             515..886
                     /locus_tag="VWZ68_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEU9372999.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHTNLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            896..3139
                     /locus_tag="VWZ68_002034"
     CDS             896..3139
                     /locus_tag="VWZ68_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU9373000.1"
                     /translation="MTEIVKASLENGIQKIRIRSEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQTLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            3346..5121
                     /gene="spxB"
                     /locus_tag="VWZ68_002035"
     CDS             3346..5121
                     /gene="spxB"
                     /locus_tag="VWZ68_002035"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEU9373001.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
BASE COUNT         1540 a          983 c         1195 g         1470 t
ORIGIN      
        1 taaaattcta tttttcgaag aaaatattat ttctataatt gacaaatgta gattttaaga
       61 gtatactgat gagtgtaatt gacaaatgta gattttggag gtatggtaat gcagatttca
      121 gatgcagaat ggcaggtcat gaagattatt tggatgcagg gggagcagac cagtacagat
      181 ttgattaggg ttttggcaga gcggtttgac tggtccaagt ccacggttca gacacttttg
      241 gctcgtctgg ttgagaaaga gtgtttgact cggaaaaaag aaggcaagtc ctttgtttat
      301 tcagcccttt taactctaga ccaaagtcgg gatttacttg tccaagatat caaagacaag
      361 gtttgttccc gtaggattag gaatttgttg gctgacttga ttgtagaatg tgaatttact
      421 cagactgact tggaagactt ggaagctgtg atttcagaga agaaatcaag tgctgtaaca
      481 gaagtaagat gtaattgtat gtaaaggaga cgtcatgtta aatagtattg taaccattat
      541 ttgtattgcc cttatcgcgt ttatcttgtt ttggtttttc aaaaagcctg aaaaatctgg
      601 acaaaaagcc cagcaaaaaa acggatacca agagattcga gtggaagtca tgggaggcta
      661 tactcctgag ttgattgtcc tcaagaaatc agtgccagcc cgcattgtct ttgaccgcaa
      721 ggatccttca ccatgtctgg atcaaattgt ttttccagat tttggtgtac atacgaacct
      781 gccaatgggg gaagagtatg tagtggaaat cacgcctgaa caggctggag aatttggctt
      841 tgcttgtggt atgaacatga tgcacggcaa gatgattgta gagtaggtgg agactatgac
      901 agaaattgtg aaagcaagct tagaaaatgg cattcaaaaa atccgtatcc gatctgaaaa
      961 aggctatcat ccagcccata tccagcttca aaagggaatt ccagctgaga ttacctttca
     1021 tcgtgctact ccttcaaact gttataagga aattctgttt gaagaagaag gtatcttgga
     1081 accaatcggc gtagatgagg agaaagtcat tcgttttaca cctcaagaat tagggcgaca
     1141 tgaattttct tgtggcatga agatgcaaaa gggaagctat acagtcgttg agaagactcg
     1201 aaaatctcta tctctcctgc aacgtttttg gattactagt atctttactg tgcctcttgt
     1261 gattctcatg attgggatgt tgacaggtag cattagtcat caagtcatgc attggggaac
     1321 ctttctagca acaacgccta ttatgttagt tgcaggtaag ccatatatcc agagtgcttg
     1381 ggccagtttt aaaaagcaca atgccaacat ggataccttg gttgcgctgg gaactctagt
     1441 ggcttatttc tatagcctag ttgctctctt tgctggtctc cctgtttact tcgaaagtgc
     1501 tggatttatc ctctttttcg ttcttttggg agcagttttt gaggaaaaaa tgagaaaaaa
     1561 tacgtcccaa gctgtggaga aattactgga cttgcaagct aaaaccgcag aagtcttgag
     1621 tgatgatagt tatgtccaag ttcctttgga acaagtcaag gtaggcgacc tgattcgagt
     1681 gcgtcccggt gaaaagattg ctgttgatgg tgtcgtagta gaaggtgtct ctagtattga
     1741 cgaatccatg gtgacaggtg agagtctgcc tgtggacaag acagttggag atactgtcat
     1801 tggctcaacc atcaatcata gtggaacgct tgtctttaga gcagaaaaag ttggctcaga
     1861 gactgttttg gctcagattg tggattttgt gaagaaagct cagacaagtc gtgcgccgat
     1921 tcaggacttg acggataaga tttcagggat ttttgtccca gtagttgtca ttttaggaat
     1981 catgaccttt tgggtttggt tcgtcttgct cagggatagt gtggttgtgc ttggagctag
     2041 ctttgtgtcc tctcttctct acggagtggc ggttttgatt atcgcctgtc cttgtgcctt
     2101 gggacttgca acaccgacag cccttatggt ggggacagga cgtagtgcca agatgggggt
     2161 tctcctcaaa aatggaactg tcttacagga aatccagaaa gttcaaaccc ttgtctttga
     2221 taagaccggg actttgacgg aagggaaacc tgtggtaaca gatgtcatcg gcgacgaagt
     2281 agaagtgttt gggttggcag cctccttgga agatgcttct caacacccac tggctgaggc
     2341 tatcgttaag cgagcgagtg aagctggact tgagtttcaa actgttgaaa attttcagac
     2401 cttgcacggg aaaggtgttt cagggcgaat caatggaaaa caagttttac ttggaaatgc
     2461 taaaatgctg gatggcatgg atatttctaa tacttatcaa gataaactag aagaactaga
     2521 aaaagaagct aagacagttg tgttcttagc tgttgacaat gaaatcaaag gcttgcttgc
     2581 tttgcaagat attcctaagg aaaatgctaa gctagccatc agtcagctaa aaaaacgtgg
     2641 tctccgaaca gtcatgctga caggagacaa tgctggtgtg gcgcgtgcta ttgcagatca
     2701 aatcggaatt gaagaggtca ttgcaggcgt cttgccagaa gaaaaagccc atgaaatcca
     2761 taaactgcaa cagtcaggga aagtagcctt tgttggggac ggtatcaatg acgctcctgc
     2821 ccttagtgta gcagatgtgg gaattgctat gggtgctgga acagatatcg ccatcgagtc
     2881 agcagatttg gtgttgacaa ccaataatct tttaggagtg gttcgtgcct ttgatatgag
     2941 taagaaaacc tttcatcgaa ttctactcaa tcttttctgg gcttttatct acaatgttgt
     3001 cggaattccg attgcagcag gagtcttttc aggtgttgga ctggctctca acccagaatt
     3061 ggcaggtcta gccatggcct ttagttctgt atctgttctg accagttccc ttctgttaaa
     3121 ttttagtaaa atagactaaa agtaatgact agatttcttt gttataaaac agaaacgaca
     3181 acactttcaa aactgtatta gaatagagaa tagagagttt tgagcagatt tttagaaaag
     3241 tcagcataaa tatgatacag tggaatagta aaaatttgga gaacgtttcc aattctatgt
     3301 aatcgtattc tccaagttta aaaaaattga aggagagtta tcattatgac tcaagggaaa
     3361 attactgcat ctgcagcaat gcttaacgta ttgaaaacat ggggcgtaga tacaatctac
     3421 ggtatcccat caggaacact cagctcattg atggatgctt tggctgaaga caaagatatc
     3481 cgtttcttac aagttcgcca cgaagagaca ggtgctcttg cagcggttat gcaagctaaa
     3541 ttcggcggct caatcggggt tgcagttggt tcaggtggtc caggtgcgac tcacttgatt
     3601 aacggtgttt acgatgcagc tatggataac actccattcc tagcgatcct tggatcacgt
     3661 ccagttaacg aattgaacat ggatgctttc caagagctta atcaaaaccc aatgtacaac
     3721 ggtatcgctg tttacaacaa acgtgtagct tacgctgagc aattgccaaa agtaattgac
     3781 gaagcctgcc gtgctgcagt ttctaaaaaa ggtccagctg ttgttgaaat tccagtaaac
     3841 ttcggtttcc aagaaatcga tgaaaactca tactacggtt caggttcata cgaacgctca
     3901 ttcatcgctc ctgctttgaa cgaagttgaa atcgacaaag ctgttgaaat cttgaacaat
     3961 gctgaacgcc cagttatcta tgctggattt ggtggtgtta aagctggtga agtgattact
     4021 gaattgtcac gtaaaatcaa agcaccaatc atcacaactg gtaaaaactt tgaagctttc
     4081 gaatggaact atgaaggttt gacaggttct gcttaccgtg ttggttggaa accagccaac
     4141 gaagtggtct ttgaagcaga cacagttctt ttccttggtt caaacttccc attcgctgaa
     4201 gtttacgaag cattcaagaa cactgaaaaa tttatccaag tcgatatcga cccttacaaa
     4261 cttggtaaac gtcatgctct tgacgcttca atccttggtg atgctggtca agcagctaaa
     4321 gctatccttg acaaagtaaa cccagttgaa tcaactccat ggtggcgtgc aaacgttaag
     4381 aacaaccaaa actggcgtga ttacatgaac aaactcgaag gtaaaactga gggtgaattg
     4441 caattgtatc aagtttacaa tgcaatcaac aaacatgctg atcaagacgc tatctactca
     4501 atcgacgtag gtaacactac tcaaacatct actcgtcacc ttcacatgac acctaagaac
     4561 atgtggcgta catctccact ctttgcgaca atgggtattg cccttcctgg tggtatcgct
     4621 gctaagaaag acaatccaga tcgccaagta tggaacatca tgggtgacgg agcattcaac
     4681 atgtgctacc cagacgttat cacaaacgtt caatacgacc ttccagttat caaccttgtc
     4741 ttctcaaatg ctgagtacgg cttcatcaag aacaaatacg aagatacaaa caaacacttg
     4801 tttggtgtag acttcacaaa cgctgactac gctaaaattg cggaagctca aggagctgtt
     4861 ggattcacag ttgaccgtat cgaagacatc gatgcagttg ttgcagaagc tgttaaattg
     4921 aacaaagaag gtaaaactgt tgtcatcgat gctcgcatca ctcaacaccg tccacttcca
     4981 gtagaagtac ttgaattgga tccaaaactt cactcagaag aagctatcaa agccttcaag
     5041 gaaaaatacg aagcagaaga actcgtacca ttccgtctct tcttggaaga agaaggattg
     5101 caatcacgcg caattaaata attcctctcg ccgaaaatca aatatgaaac ttgtagactt
     5161 tattctttga ttttcataga gcagaact
//
LOCUS       DAVKEV010000084         4399 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVKEV010000084 DAVKEV010000000
VERSION     DAVKEV010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4399
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.084"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            71..163
                     /locus_tag="VWZ68_002036"
                     /pseudo
     CDS             71..163
                     /locus_tag="VWZ68_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(589..786)
                     /locus_tag="VWZ68_002037"
     CDS             complement(589..786)
                     /locus_tag="VWZ68_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9373002.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
     gene            complement(771..1049)
                     /locus_tag="VWZ68_002038"
     CDS             complement(771..1049)
                     /locus_tag="VWZ68_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEU9373003.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            complement(1088..1873)
                     /locus_tag="VWZ68_002039"
     CDS             complement(1088..1873)
                     /locus_tag="VWZ68_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9373004.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            complement(1875..2693)
                     /locus_tag="VWZ68_002040"
     CDS             complement(1875..2693)
                     /locus_tag="VWZ68_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEU9373005.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            complement(2695..3687)
                     /locus_tag="VWZ68_002041"
     CDS             complement(2695..3687)
                     /locus_tag="VWZ68_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9373006.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
BASE COUNT         1483 a          927 c          757 g         1232 t
ORIGIN      
        1 gtatatcatt taaaaaaatt taagtcaaaa aaattaacat tagttaattt attttttagc
       61 acacattaaa aaataagatt agtactcaat gaaaatcaaa gagcaaacta ggaaactagc
      121 cgcagattgc tcaaaacagt gttttgaggt tgtagatgga actgacgtag tcagctcaaa
      181 acactgtttt gaggttgtgg atagaactga cgaagtcagt aaccatacgc acggcaaggc
      241 gacgttgacg tggtttgaag agattttcga agagtataag tccaaaactt tcgttaaccg
      301 ggatacatta taagcacatt cataccatca aaaatagtag caataaactt gaacaactac
      361 cagaaacacg aaaacaggca taattgataa aatattagcg ctattaaaca atataaataa
      421 ccgctaagag taaggcttaa cggttatctt ctacctatct attttttcaa atcctcagtc
      481 gtttatctac ctataaccta ggctttacga gtgccttgct ctaccaacta agctaaatcg
      541 gcgattacac ttacagtata gcactctgag aatagatgtc aagtaatatt attcaagctt
      601 tttaatcaaa atctgacaag gattttgcgg attccatagt tgaggaaaaa tctctaactt
      661 tttaaagcca agacctcgat aaaagtcatt tgttcgatca taatctttat tagaaccttc
      721 tgccactgtt ttgacctgca gataaccaac ttttttacga gcttcactct ctaaagtagc
      781 aagcaattgg ctcccaattt ttctaccttg ataagctttt ttacgccgag acaatcaatc
      841 tctgcacaat cttcactcga ataggataag cttacaaatc tagtcaaatc actctcctga
      901 taggcggtcc aaacttgcag tgtcgtggtt ccttctatat aggcttgtgt gctttctggg
      961 attccaaacc attctggcaa atccttcaaa acctcagcga caactgcctt tttttgattt
     1021 tcatccttga cttcttcaat tacaaacatc ataagtttct ttcttgattt tagtcttact
     1081 ttagctttta cgaacccgca ctttcgtagg aatctaagcc cttatcccaa agtttaaggg
     1141 aaataacaaa gaaaaccaga gaaatcaaca tcaaacctcc tacgttaaag aacacatcct
     1201 tttcctgtaa gaaatagcta gctggatagt aggctgtaaa ggcgaaaggc acgataaagc
     1261 taatcaacca acgaagaaga gaattgtaaa tagaaatcgg atacttagca aagtcattga
     1321 acatatagaa gatgtaaatc atggcgcctg actgcttagt ccaaaaggcg atactggctg
     1381 ttgcgatttt aagagaagta taaatcaagg tcgcaaaagg aatacaaact aggaaaagca
     1441 ggaattttgg aagagtccaa acaatgctgg tcactgttgt tcccaataaa ataccaccga
     1501 ctaagagttc acccaaggca tcaatctgaa aggtttcaac taggatgtga aagagaggat
     1561 tgatgggacg agtcagatac ttgtcaaact ccccttttcg gactaggcgt tgccctagtg
     1621 cccagagatt gtcaaaaaag agatggtcca ttcccttggg aatcaaggaa aatccataaa
     1681 tgaaagctat ctcttgaaag gtccagcctt ctaggaatgg aatatgttga aagatgacat
     1741 tgagaaacaa gagattcaag ccttgagtca gaaagactcc caagacacca accacaaaat
     1801 ctaccttata ttccatgatt tgtttgatgt attgtctgat aaaaatcaga tgcattcgtt
     1861 gatatttttt catactaacc tccttgaatg gtgataaagg actggacccg tttccaaatt
     1921 aactgagaca atcccaccat cactaagagc cagaagaact gcaaaaggag tgcctgaaga
     1981 atctgactgg catcgtattt tccaacaatg atcataactg gagtataaat caaggatgaa
     2041 aaaggcaaaa aggagagaat atctgaaaca acctttggaa aaaatgccaa gggaatcaaa
     2101 ctccccgaca taaaagccac tatggaagtc ttaagtaggt tggaacccca aagattttta
     2161 aacacaaagg ctgaaaatcc aaagcaaata ttaaagaaaa agttaatcag ataggcgagc
     2221 gttaagctaa aaagataaat gacagttaat cctagcacct ctacaatacc ttgacccgat
     2281 atgattttca tcaagacaat gacacttaaa aatggaaggc caacgctgat aaaaatcaac
     2341 cacttggaac caagctcggt gaaaagatag gaggccgcaa aatgcactgg tcgcaacaaa
     2401 cgcatgataa tggagccatc cttgacctcc tccccaatca taaaggacga atcggatcta
     2461 gtcagaagat tggtcacaaa actcatgatg atgtagaggg tgatatccgc catactgaag
     2521 ccctgaatca aagactcttg cgaagaatca aagacagcct tccagagata aaaggccaca
     2581 aaagccccca tgacatcgcc aatccgatag agaataaagt tgactcggta agtaatcaac
     2641 tcctgaaccc ctgcattgat aaagggttta taacgtctcc ataatttgat catcctagag
     2701 ctcctttcgg tagaagcgac ggataatatc ctcaatatcc gtatccacca tcttcaaatc
     2761 gcggatttca aaatcagaca gggtttgctt gataatgtca gctgactggt agcgagaact
     2821 atcaaattca atgttgaggc tgtttccttg tctatcaatg gtcatatcag acagaccttc
     2881 atagtgagag acgagatgac tttgacctgg tagcagttca aaagagagag tcttcatctt
     2941 accaaaggtc tccttgagtt ggctcaccgt tccatcaaaa atctcttgcc ccttgtcaat
     3001 catgaaaatc cgatcacaaa gttgctcaat atcactcaaa tcgtgagtgg tcaaaagaat
     3061 ggtagtttct tcctcttgat tgatctgagt aattgcccga cgaatattat ccttaaccga
     3121 aacgtccaaa ccaatggtcg gctcatctaa aaaaagaacc ttgggattgt ggagcaagga
     3181 ggccgcaata tccgcccgca tccgttgtcc cagtgaaaga gtccgcacgg gatccttgat
     3241 aaagtccttc aaatccaaga cttcattcaa aaagtccatg cgcttatgaa agagcgagtt
     3301 tggcacatca taaatctctt ttaagacagt gtaggtctct tgcagagcca aatcccacca
     3361 tagctgggtg cgttgtccaa agactacgcc aatatctttg acataatctt gccgattgtc
     3421 ctggggaatc ttgccgttaa tccgacaaaa accagatgtt ggtttcaaaa ttcctgtcag
     3481 cattttaatg gttgtcgact tcccagcacc atttgccccg ataaatccta aaatctgccc
     3541 ttttggaacc tcaaaggtca aatccttgac cgcttcaaag gtctgctttt caggatgaat
     3601 aaaggagcgc aaagccccct tcaagcccgg ttccttaaca gtcttcacaa aatttttctg
     3661 aagatgttcc acttctatca ttgccatatc tatctcccta tcgtaaggaa tagcaacatt
     3721 gtgtttttaa ctacaaatat tctaaatcct tgctttctac accttctaca ttttattact
     3781 acaaaaggct ttataccaac ctattatagt ccaataaaaa acgaaatgca agcgtttgcc
     3841 tatggattgt gaaattagga tttctctcat aaaataatac ttttaatcaa aaattctgtt
     3901 taatagttta aattaccaac ctactcatct tctcaccaga gggcggtatt aactttgatc
     3961 ataaaatcgg atactccctc tatccagaaa atatgctcag aatgattgtc tctaaacaat
     4021 acctgctctt ttacctcatt catgaaaaag aagtccatac cctgagaatt atcaactcac
     4081 gcatcgacta cctaaaccaa ctcgaccacc tctttcgtac atgtaggaaa ctattttcct
     4141 cacaaataat ctcattataa aatccaataa atttttttag ctcacttgaa tattttcttt
     4201 gtatcgtttt atcagcttca atctgatcta gacttgttac cttggaacga cttgaaataa
     4261 cctttataaa ataacactta aggctttcat catctcgtat aaatttttca atagtgatat
     4321 aaaaagcttt catattctgt ttgtaatcag atatcaattg attaatttta tcattctgat
     4381 gaagattcga taccataat
//
LOCUS       DAVKEV010000085         4346 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVKEV010000085 DAVKEV010000000
VERSION     DAVKEV010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4346
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.085"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            24..1049
                     /locus_tag="VWZ68_002042"
     CDS             24..1049
                     /locus_tag="VWZ68_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU9373007.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1039..2046
                     /locus_tag="VWZ68_002043"
     CDS             1039..2046
                     /locus_tag="VWZ68_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9373008.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            2046..3053
                     /locus_tag="VWZ68_002044"
     CDS             2046..3053
                     /locus_tag="VWZ68_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9373009.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFVLLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLADPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            3053..3847
                     /locus_tag="VWZ68_002045"
     CDS             3053..3847
                     /locus_tag="VWZ68_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9373010.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
BASE COUNT         1576 a          633 c          740 g         1397 t
ORIGIN      
        1 tgaaatatgt ttaaggagtt tttatgaaaa acaaattttt tctaatagct attttagcta
       61 tgtgtatagt ttttagcgct tgttcttcta attctgttaa aaatgaagaa aatacttcta
      121 aagagcatgc gcctgataaa atagttttag atcatgcttt cggtcaaact atattagata
      181 aaaaacctga aagagttgca actattgctt ggggaaatca tgatgtagca ttagctttag
      241 gaatagttcc tgttggattt tcaaaagcaa attacggtgt aagtgctgat aaaggagttt
      301 taccatggac agaagaaaaa atcaaagaac taaatggtaa agctaaccta tttgacgatt
      361 tggatggact taactttgaa gcaatatcaa attctaaacc agatgttatc ttagcaggtt
      421 attctggtat aactaaagaa gattatgaca ctctatcaaa aattgctcct gtagcagcat
      481 acaaatctaa accttggcaa actttatgga gagatatgat taaaattgat tcaaaagcct
      541 taggtatgga aaaagaaggt gatgagttaa tcaaaaatac tgaagctcgt atatccaaag
      601 aattagaaaa acatccagaa atcaaaggaa aaatcaaagg aaaaaaagta ttatttacta
      661 tgattaatgc tgcagataca tcaaaattct ggatttatac tagcaaagat ccaagagcaa
      721 attatttaac agatttaggt ctagttttcc ctgaatcatt aaaagaattt gagagtgaag
      781 atagttttgc aaaggaaatt tctgcagaag aagcaaataa gataaatgat gctgatgtaa
      841 tcataactta tggtgatgat aaaactcttg aagctttaca aaaagatcct cttttaggta
      901 aaataaatgc aattaaaaat ggtgccgttg ctgtaattcc agataataca ccgttagcag
      961 cctcatgcac tccaacacca ctttcaataa actatactat tgaagaatac ctaaatcttt
     1021 taggaaatgc atgcaaaaat gcgaaataaa aaacaaataa acctaggcat aatttttgta
     1081 atctgcctag gtcttcttat tacaatattt ttgtcattaa agcttggaac aaaagaaatt
     1141 aatatcagag attttttagc agcttttgga atgggtaata caaatgatga ttttattaaa
     1201 tcaattatat ataaaagaat acctagaact atttttgcaa ttttagcagg ttctagtctt
     1261 gccataagcg gtgtattgat gcaatcagtt actagaaacc caatagctga tccaggtata
     1321 ctcggtataa acacaggagc aagtcttagt gtagtaattg gtctttcttt tttaggaatt
     1381 tcatcaagca taagccatat aagttttgca atcattggtg gcttagtaag tgcaattttt
     1441 gtatacgcga ttgctgtaag cggaaaagca ggccttaccc ctataaaact tgccttatca
     1501 ggaacttgtg ttagtatggc tttaagcagt tttgtaagtt ttttaatttt accgaataat
     1561 aacgtcttag acaaatttag attttggcaa ataggtagcc ttggagcagc tacattatct
     1621 tctatatcta cactactacc ttttataatt ttaggtcact tgatagctat atttatttca
     1681 tcagatttaa acgctttagc tatgggtgat gaaatggctg ttggtcttgg agttaatgtt
     1741 aataggataa gatcacttgc aataattgca agtgtgcttt tatgttcaag tattactgca
     1801 attggtggac ctattggctt cgtaggtctt atagttcctc acttttgtgg cttatttata
     1861 agcaaagata tacgcacaat gaccatttct tcatctttta taggtgcaga gctcttgctt
     1921 atatgtgata taatcggccg tatgttaggt aaaccaggtg aaattgaagt agggataatt
     1981 actgcaataa tcgggggtcc agtacttatt tatgtaacta tgaaaaatag aggggttaat
     2041 aactaatgca aaatttaatt ataggtattc aaaaaagaaa aaatagaata acactatttt
     2101 cctcactatt tttattaata ataatcagtc tatcattttt cgttttactt atcggagatg
     2161 aaagttattc tttttcaact ttgattaaag tcttaaatag tgaaactgtt cctggagcta
     2221 gtttttcgat tatggaaatt agattaccaa aattattagc aggaattata gctggctggt
     2281 cttttggatt ggcaggattt atctttcaaa ctatgttaag aaatcctctt gcaagtcctg
     2341 atataatcgg tgtcacaagt tcttcatcta ttgcagcggt cttttgcata ttggtattaa
     2401 aaacaaatag tttaactact ggaattattt caataacttg tggactaaca tcatctttaa
     2461 tattattttt actagctaaa aaagatggtt tttcagcagc aagactgata atattaggca
     2521 ttggttttca agctgtcaca agagcaggca cctcattttt attgttgaaa gtagcaagat
     2581 atgaattaca agaagttatg agatggctca gtggctcttt atcttttaca aagttagatg
     2641 acatacctct tgttctaata gtaagtatta ttgctactat attagtttta ttttttaata
     2701 aaagactaga aattattgaa cttggtgaag aaatagcaat cggacttgga gcaaatcccg
     2761 agctttcaag gcttgtttta attttttgcg ctgtatcttt aactgctttt tctacttcaa
     2821 ttacaggacc aatagcttgt atatcttttt tagctgatcc catagcctta aatattggca
     2881 agaaaagaag cccaatatta gctggattgg ttggaatttt actagttttg ttatcagaca
     2941 tattctctca aaatatttta ccagctagat atccagtagg tgttgtaact ggcttgttag
     3001 gttcaccata cttaatatat ttactaataa aaatgaacag gaggaatata taatgaaagg
     3061 tctgtggtca aataatctta cctgcggtta tgatgaaaaa ataatcttgg aaaatataaa
     3121 tataaaaata cctgaagaaa aaatatcagt tattattggg tcaaatggtt gtgggaaatc
     3181 aacactcatt aaaaccttgt ctcgacttat aaagccatta gagggagaag tattgcttga
     3241 taataaatca attaattctt ataaagaaaa agatttagca aaacacatag ctatattacc
     3301 tcaatctcca ataatccctg aatcaataac agtagctgat cttgtaagcc gtggtcgttt
     3361 cccctacaga aagcctttta agagtcttgg aaaagatgac cttgaaataa taaacagatc
     3421 aatggttaag gccaatgttg aagatctagc aaataaccta gttgaagaac tttctggggg
     3481 tcaaaggcaa agagtatgga tagctctagc cctagcccaa gatacaagta tcctactttt
     3541 agatgagcca actacttact tggatatctc atatcaaata gaactattag acctcttgac
     3601 tgatctaaac caaaaatata agacaaccat ttgcatgatt ttgcacgata taaatctaac
     3661 agcaagatac gctgattacc tatttgcaat taaagaaggt aaacttgttg cagagggaaa
     3721 gcctgaagat atactaaatg ataaactagt taaagatatc tttaatcttg aagcaaaaat
     3781 tatacgtgac cctatttcca attcgcctct aatgattcct attggcaagc accatgttag
     3841 ctcttaataa ttgaatattg gaattcattt aaaagtcgca aattttgaac tgaccctcaa
     3901 aagttaggcc aaaaaactaa ctaaaggagg tcagtttttt aatggcaaat acagcacaga
     3961 atttaagata aaattagtaa aagaatatca tgaatgaaaa ataggatata gagaataaca
     4021 gcaatattaa aaagatcagg actgataata aacaaaaaga aagtacaacg actagttcaa
     4081 aagctaaaac ttcaagtaaa aagttattca agaaaatcta gaaaatactc atcctacaaa
     4141 ggacaggtag gaaaaatatc agacaacaaa ataaaaagaa atatttatta ccgaaaaaaa
     4201 ggggaaatcg agtcaagtac caacaggctc atctattcca aaaagatatt tactcgatgg
     4261 aaaaactcct agaattagtg ctacaaatat tgacaatggt atcttaggtt actacgaaga
     4321 tatagatgat aaaaattata gagttt
//
LOCUS       DAVKEV010000086         4011 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVKEV010000086 DAVKEV010000000
VERSION     DAVKEV010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4011
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.086"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(146..1207)
                     /gene="dinB"
                     /locus_tag="VWZ68_002046"
     CDS             complement(146..1207)
                     /gene="dinB"
                     /locus_tag="VWZ68_002046"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEU9373011.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            1556..3880
                     /gene="pflB"
                     /locus_tag="VWZ68_002047"
     CDS             1556..3880
                     /gene="pflB"
                     /locus_tag="VWZ68_002047"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEU9373012.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
BASE COUNT         1207 a          846 c          777 g         1181 t
ORIGIN      
        1 aaaaaccttg aaggggcaac tcttcaaggt tttatactct tagaaaatct cttcaaaccg
       61 cgtcagcttt atctgcaacc tcaaaacagt gttttgagca gcctgcggct agcttcctag
      121 tttgctcttt gattttcatt gagctttaaa atccagtcag ggtaatcccc aataggcgga
      181 cacctctttc tttctcgctt aattcttcat agagttgcag ggctatttgg cttatctgac
      241 tagcatcttg tgttttttga gcaagacttt ttcgtttggt aagagttgaa aagtcctcgt
      301 agcggatttt caaaatgaca atttttccag ctttttcttg ttgatgtaga ttgagagcga
      361 ctttttctga tagaagagtc agctcttttt tgatatcttc ctcagcaagg agaatcttcc
      421 cgtaggtttt ctccttgccg attgatttac ggatgcgatt ggatttgact ggagagttgt
      481 gaatgccacg agcctttcga tacagatcat agcctagtct accaaaacgg tctattaggg
      541 ttacctcagg aacttcaagt aaatcagcac cagtaaaaac gcccatttga tgaagacgtt
      601 ctactgtctt ttttcctact ccatgaaatt tggaaatatc catttgtttg agaaaatcct
      661 cagcctgttc aggtagaatc actgtcaaac catgtggttt ttgataatca ctcgccattt
      721 tagctaagaa tttgttgtaa gaaacgcctg cggaagcagt tagatggagt tcttgccaga
      781 tatctttttg aatgaggcga gcaattttga ccgctgactt gataccgagt ttattttctg
      841 tcacatccaa ataggcttcg tcaatgctca tgggttcaat caaatctgta tagcgcttaa
      901 aaatagctcg aatctggagt cccacagact tgtatttctc ataattccct gagataaaga
      961 cagcctgggg acaacgttca taagcttcct tggaactcat ggcagaatgg acaccaaaag
     1021 ctcttgcctc ataactacag gtagaaacga ctccccgtcc acctgtttgc cgagggtcgc
     1081 ttccaataat gacaggtttt cctctgagtt taggattatc cctgatttcc actgcagcaa
     1141 aaaaggcatc catgtcaata tggatgattt ttcttgacaa atcatttaac aaaggaaaaa
     1201 tcaacatgcc tagcaccttt ttatactctt cgaaaatctc ttcaaaccac gtcagctcta
     1261 tctgcaacct caaaacagtg ttttgagcaa tctgcggcta gcttcctagt ttgcttttcg
     1321 atttccattg agtgttactg cttattttct tttattatac ccttttttct gaaaaaaaga
     1381 aaaaaggact ttattttttc aaaaatataa tacagtttga aataaaatat agactgtttt
     1441 agaaaagaaa gtgtaaaaat agggaatttt cacttgttga aatcggttac tatatggtat
     1501 acttgtctta tgaatgtaac agatgactgt tactagaaaa aaagaggaca ttaatatggt
     1561 tgttaagaca gttgttgaag cacaagatat ttttgacaaa gcttgggaag gcttcaaagg
     1621 cgtagattgg aaagaaaaag caagtgtatc acgatttgta caagctaact acacacctta
     1681 tgatggagac gaaagcttcc ttgcaggacc aacagagcgt tcacttcaca tcaagaaaat
     1741 tgtagaagaa actaaagcac actacgaaga aactcgtttc ccaatggaca ctcgtccaac
     1801 atctatcgct gatatccctg ctggatttat cgacaaagaa aatgaagtta tctttggtat
     1861 ccaaaatgat gaactcttca aattgaactt catgccaaaa ggtggtatcc gtatggctga
     1921 aactacttta aaagaaaatg gatacgaacc agacccagct gttcacgaaa tcttcactaa
     1981 atatgtaaca acagttaacg acggtatttt ccgtgcctac acttcaaata ttcgtcgcgc
     2041 tcgtcatgca cacactgtaa ctggtcttcc agatgcatac tcacgcggac gtatcatcgg
     2101 tgtttacgca cgtcttgctc tttacggtgc agactacttg atgcaagaaa aagtaaacga
     2161 ctggaatgca atcaaagaaa tcgatgaaga aacaatccgt cttcgtgaag aagtaaacct
     2221 tcaataccaa gcattgcaac aagttgttcg cctgggtgac ctttacgggg ttgatgttcg
     2281 caaaccagcg atgaacgtga aagaagcaat ccaatgggtt aacattgctt tcatggctgt
     2341 ctgccgtgtg attaacggtg ctgctacatc tctaggtcgt gtaccaatcg tattggacat
     2401 ctttgcagaa cgtgaccttg ctcgtggtac atttactgaa tcagaaatcc aagaattcgt
     2461 tgatgatttc gttatgaaac ttcgtacagt taaatttgct cgtacaaaag cttatgacca
     2521 attgtactca ggtgacccaa cctttatcac aacttctatg gctggtatgg gtaacgacgg
     2581 tcgtcaccgt gttactaaga tggactaccg tttcttgaac acacttgaca acatcggtaa
     2641 ctcaccagaa ccaaacttga cagttctttg gactgacaaa ttgccataca acttccgtcg
     2701 ctactgtatg cacatgagcc acaaacactc ttctatccaa tacgaaggtg taacaacaat
     2761 ggctaaagac ggatatggtg aaatgagctg tatctcatgc tgtgtgtctc cacttgatcc
     2821 agaaaatgaa gaacaacgcc acaacatcca gtacttcggt gctcgtgtaa acgttcttaa
     2881 agcccttctt actggtttga atggtggtta cgacgatgtt cacaaagact acaaagtatt
     2941 tgatatcgaa ccaatccgtg acgaagttct tgaattcgaa tcagttaaag cgaactttga
     3001 aaaatctctt gactggttga ctgacactta cgtagatgcc ttgaacatca tccactacat
     3061 gactgataga tacaactacg aagctgttca aatggccttc ttgccaacta aacaacgtgc
     3121 caacatggga ttcggtatct gtggatttgc taacactgtt gatacattgt cagctatcaa
     3181 atacgctaca gttaaaccaa tccgtgacga agatggctac atctacgatt acgaaacaat
     3241 cggtgactac ccacgctggg gtgaagatga cccacgttca aacgaattgg cagaatggtt
     3301 gatcgaagct tacacaactc gtctacgtag ccacaaacta tacaaagacg cagaagctac
     3361 agtatcactt ttgacaatca catctaacgt tgcttactct aaacaaactg gtaactcacc
     3421 agttcacaaa ggtgtatacc tcaacgaaga tggttctgtg aacttgtcta aacttgaatt
     3481 cttctcacca ggtgctaacc catctaacaa agctaaaggt ggttggttgc aaaacttgaa
     3541 ctcactttct agccttgact ttagttatgc agctgacggt atctcattga ctacacaagt
     3601 atcacctcgc gctcttggta agactcgtga tgaacaagtt gataacttgg taacaatcct
     3661 tgatggttac ttcgaaaacg gtggacaaca cgttaacttg aacgttatgg acttgaacga
     3721 tgtttacgaa aaaatcatgt caggcgaaga cgttatcgta cgtatctctg gatactgtgt
     3781 aaacactaaa tacctcactc cagaacaaaa aactgaattg acacaacgtg tcttccacga
     3841 agttctttca atggatgacg ccttggatgc attgagctaa tcaagttcgg ctctttgtca
     3901 actgcagtgg gttgaagtcg gctaagctcg agaaaggaca aaattcgtcc tttctttttt
     3961 gatgttcaga gcgataaaaa tccttttttt gaagttttca aagttccgaa a
//
LOCUS       DAVKEV010000087         3965 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVKEV010000087 DAVKEV010000000
VERSION     DAVKEV010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3965
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.087"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..823)
                     /locus_tag="VWZ68_002048"
     CDS             complement(<1..823)
                     /locus_tag="VWZ68_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU9373013.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFATKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVD"
     gene            1447..1629
                     /locus_tag="VWZ68_002049"
     CDS             1447..1629
                     /locus_tag="VWZ68_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU9373014.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            1639..2004
                     /locus_tag="VWZ68_002050"
     CDS             1639..2004
                     /locus_tag="VWZ68_002050"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU9373015.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            2001..3179
                     /locus_tag="VWZ68_002051"
     CDS             2001..3179
                     /locus_tag="VWZ68_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU9373016.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     "
     gene            3348..3900
                     /locus_tag="VWZ68_002052"
                     /pseudo
     CDS             3348..3900
                     /locus_tag="VWZ68_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1436 a          656 c          689 g         1184 t
ORIGIN      
        1 catccacagc cgccttgtag cagttggtta ctgttgatac gtagtgaata gacttcatac
       61 gtccttcgat ttttagactg tccacaccat tttcaatcat atctggaata tggtcaatca
      121 tagacatgtc aacggctgac attgaaaatt cttctggaat ctcaccctgc aaactcttac
      181 gttctttccc aaatggcata tcgtaaaggt cgtatttcca acggcatgac tgagaacatc
      241 caccacggtt ggcatcacgc atactcatgt ggtttgaaag agtacaacgt ccagagtatg
      301 aaatacacat agctccatgg acaaaggctt caatttcaac atctgtacgt ttgcggattt
      361 cagctaattc ttccattgaa acctcacgcg ctaaaacgac acgagtcaag cctagctctt
      421 tccagaactc aagggtttca tagttagtgg cactggcttg ggtagaaagg tggatttcaa
      481 ggcctggtgc ttcagtcgct gcaatcataa tcaaggctgg gtcagatacg ataactgctg
      541 caatcccgat atcacgcagt ttacggaacc actcaccagc accagcttca tttccttcgt
      601 gcataaccat attagccgct acatagacct tggcaccata cttggtcgca aactgcacgc
      661 cttcttccat ctgttcgaaa gtaaagtttc ccgcacggct acgaagacca taggcctgac
      721 caccgataaa gacagcatct gctccatact gaacagctac ctttagcttc tctaaagtcc
      781 ctgcaggtga taaaacctca ggacgtttta atgtttttgt catgatttct cctatttgca
      841 atataaaagt ttgacatttt tccttctcat tttatagtaa ataaaggata aaatcaagcc
      901 tagacggatt gttttgacaa ttctaatctt ttagactttg cataataact attaaacagt
      961 cgaaaattac cccagtttta acaagtagtc aaaaagtcta aaaaagtaaa aaccagtatc
     1021 ccaagatact gactcgtaaa aatatataaa ttagtcctta gatgactact cccactctgt
     1081 tgctcctata atggaaaagg attgatacag tctagaatat cgctttttta tttattattc
     1141 tgatataaaa ctgttagaat tgattttttg ttttataccc aaatatgaat agagacgtag
     1201 ctaataagtt gaataacata tttggaaaaa tgagaaatag caatattact agaactttta
     1261 gaaacaatca atatttaaaa agaaaaaagc tcaaagaatt tattaaacca tgttataata
     1321 gatatagcta taattttatt tataacaaga ggatagaaat gaccgaatta gaaagaaaaa
     1381 atcgaaaaat tagctaagaa atattctgat aacttaaaca tcaaagttca agagagagtt
     1441 cgtgaaatgg caaatgataa taagagccat tatttgatat acagagtttt aggtatttca
     1501 tttgaagaag gagaaaatat cgatttgtat caaaataaag gtcgtttttt atacaaatat
     1561 gctggttcat ttttagaaga agctgcagta ctatccttta acgaaaaatt tggtacagaa
     1621 aatacttaaa aagttaacat tcctaattct gaaagtacaa aacctaagac ttttgaaatt
     1681 gattgtttag tcggagaaaa acacgcatac gaaataaaat ggtgggatgc aactacagat
     1741 ggagaccata taactaaaga acacactaga ataaaagtta ttcataacaa aggatatata
     1801 ccaattcggt taatgttcta ctatccaaat agaactcaag ctataaaaat tcagcaaact
     1861 ttagaaacat tgtataacgg tattggaggg aaatattatt atggagattc tgcctgggaa
     1921 catttaagag cagtgaccgg tattgattta cttagtattc taacagatat tgcaaataaa
     1981 aaaacagggg taaaatcaaa atgacagtat taaaaggaga taacttagaa atattaaaaa
     2041 ctattgaatc ctcaagtatt gatttaatct atatggaccc tcctttcttt acacagaaaa
     2101 cccaaaaatt atctaataac aaaaatatta tgtattcatt cgaagatacg tggacttcga
     2161 ttgaggatta caaagaattt ttgtctgtaa gattagaaga atgcaaaaga gtgctaaaaa
     2221 atagtggcag tattttcgtt cattgtgata aaattgcaaa tcatcatatt agattaattt
     2281 tagataatat ctttggagca gatatgtttc aaagcgaaat tatatggaac tataaacgat
     2341 ggtctaattc aaaaaaggga ttattgaaca atcatcaaaa catttacttt tattcaaagt
     2401 caaaagattt taaatttaat acaattttta cagagtattc ttctactaca aatatcgacc
     2461 aaatactagt ggaacgaaaa cgagatggaa actctaaaac tatatataaa gttgataata
     2521 atggtaacta tattctagca aaagagaaaa atggagttcc cctttcagat gtttggaata
     2581 taccatttct taatccaaaa gctaaagaaa gagtaggtta tcctacacaa aaacctattc
     2641 tgttattaga acaaattata aagattgcta ctgataaaaa tgatatagtt ttagacccgt
     2701 tctgtggaag cggaactact ttagtagcct ccaagatttt gaatagaaat tatatgggga
     2761 ttgatttatc tgaggaagct atcaatataa ctcagcaacg tctggaaaat gttataaaaa
     2821 caagttcaaa tttattgaat aaaggaatcg aagcatatag aaccaaaact gaggaagagg
     2881 aaaacattct taaattatta caggcaaaaa ttgttcaaag aaataaagga attgatggtt
     2941 ttttacctaa acattttcaa aaaaaaccga tacctataaa aattcaaaaa aataatgaat
     3001 gtctgaatga gagtatctct ttattacaga atgctataaa ctccaaaaaa cttgattttg
     3061 gagtagttat aaaaactcat tcagataatt tattatttga ttttgatacg attcctgaaa
     3121 atataatagt agttgaccat tttgaactta caatcgaaaa atggttaagt aaaagttaac
     3181 agttactata gtttgcaaat tatttacaga aagaacaaga attcctagga gattattctg
     3241 gctatgttca ttgtgacatg ttgcggcagt aacttaggac tttagtcctc tagttctgcc
     3301 tatgcgatag cagtccaaag tttaggagta aggcgacgct aagcttggta aactgcgaac
     3361 agctagaagc ttatcgtcaa ctggaagaag ctgcacttgt tggatgttgg gcgcatgtga
     3421 gaaggaagtt ttttgaagcg acccccaagc aagcagataa atcatcctta ggagctaaag
     3481 gtttagctta ttgtgatcag ttattttcct tggaaagaga ctgggaggct ttgccagctg
     3541 atgaacgact acagaaacgt caagaacatc tccaacccct aatggaagac ttctttgctt
     3601 ggtgccgccg tcagtcagtt ttagcaggtt caaaactagg aagggcaatt gaatacagcc
     3661 tcaagtataa agaaaccttt aagaccattt taaaagacgg acatctggtc ctttccaata
     3721 atctagctga acgcgccatt aaatcattgg ttatgggacg gagtaaaaga gtccagtgga
     3781 ctcttttagc ctgagctcag tttaaaaaag cgagggtggt tattttctca aagttttgaa
     3841 ggagctaaag caagagctat tattatgagt ttgttggaaa cagctaaacg tcatcaatta
     3901 tagtgcgttg aatctataac agtacgcatc gactgctaaa atatttctat aaatcaattt
     3961 tcctt
//
LOCUS       DAVKEV010000088         3890 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVKEV010000088 DAVKEV010000000
VERSION     DAVKEV010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3890
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.088"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(126..758)
                     /locus_tag="VWZ68_002053"
     CDS             complement(126..758)
                     /locus_tag="VWZ68_002053"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEU9373017.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKDDQENWQEG"
     gene            complement(792..1493)
                     /gene="pyrF"
                     /locus_tag="VWZ68_002054"
     CDS             complement(792..1493)
                     /gene="pyrF"
                     /locus_tag="VWZ68_002054"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEU9373018.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            1814..1906
                     /locus_tag="VWZ68_002055"
                     /pseudo
     CDS             1814..1906
                     /locus_tag="VWZ68_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2228..2941)
                     /locus_tag="VWZ68_002056"
     CDS             complement(2228..2941)
                     /locus_tag="VWZ68_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9373019.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNETLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(2934..3767)
                     /locus_tag="VWZ68_002057"
     CDS             complement(2934..3767)
                     /locus_tag="VWZ68_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9373020.1"
                     /translation="MIEVSHLSKSFGDKIALNDISFTVKEGQIFGFLGPSGSGKTTTI
                     NILTGQLLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMSLYNNLLFYSKFY
                     NISKLRVDNLLKRVGLYDSCKMVAGKLSTGMRQRMLLARALINKPAVLFLDEPTSGLD
                     PTTSRTIHELILELKTAGTTIFLTTHDMNEATLLCDYVALLNKGKLVEQGAPSELIQR
                     YNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLEDIFITLTGGKLN
                     A"
BASE COUNT         1220 a          785 c          654 g         1231 t
ORIGIN      
        1 catattacat tttcattata tcaataaaag aaagcgttgt caattatttt atttaaaata
       61 ttgtcatatt ttaaataaaa tggtaaaaga ggctcggtag cctcgtctct ctttatctta
      121 ctgacctaac cttcttgcca attttcttgg tcgtctttaa agcgttttag aagatcaagg
      181 ccctctggcg tgatgtaacc ttcttcttgg gctagatgga taagctcgct atagtttgaa
      241 agcgtcacaa gtttaacacc agcatctgca aagttcttat ctgcttttgg caattggtag
      301 ctgaaaatcg ctacaactcc aagcacatct gctccttctc gcttggctgc tgctacagct
      361 tcaagaactg aaccacccgt tgaaataagg tcttcaacca ctaccatttt ttgaccttga
      421 gctacgcgac cttcgatttg attaccagct ccatggtctt ttggtttgct acggatgtag
      481 gcaaaaggca agtccatctt atcagcaata atggctccgt gtggaatccc tgctgttgca
      541 gttcctgcaa tcacttctac ttcaggaaag gcttctttga tagcttccac aaaaccattt
      601 tcaattaggg tacgagtttc tggataggct agtgtcacac gattatcagt gtaaatcggt
      661 gacttgatac cagatgccca agtgaagggt tcctctggtt tgaggtaaac ggcttggatt
      721 ttcaagaggt ggctagcgat atctttagca agtgtcatgg tattctcctt ttatttttct
      781 aatctagttc tttaattcca gtcctgtgtc cattcatcct tgatggcatg ataagctgca
      841 acaggatcct cagcttgggt aatgggacgt cccactacga tatagtcact gccgatttga
      901 taggcatcag caggtgtcat gactcgtttt tgatctccaa ctgcaacacc agctggacga
      961 atccctggtg tcagacagat aaaatctgga ttggtagcct gcttgatgac ttgtacttcc
     1021 tgagccgagc aaacaacacc atccaagcca gcttcagctg tcttcttggc atagtgaatc
     1081 acagactctt gcagactggt ttggatattt tgaaactcct gcatctgagc ttctgacgtt
     1141 gatgtgagct gagttacagc gatcaatttg gcttgacttc caagaccttc acgcgcagcc
     1201 ttcatcatct ctacaccacc agccgcatga acattggtca tatccacacc aagctgagat
     1261 aggatcttca ttgctgactt gactgtatta ggaatgtcat gaagtttgag atccaaaaag
     1321 acactatgac ccaaaccttt taagtaggac acaatctcag gccccgctgc gtaataaagc
     1381 tccatcccta ccttgagata aaggctttct tctgctggga aaagagctaa aaattccttg
     1441 accgcctcaa aactaggaaa atcaagagca atgattggac gatgttctcg cataggtttc
     1501 tccttttacc tttactagtg agagagtctg gccaacagaa gccacgaaaa aaggaacctg
     1561 ccaacagcaa ggttccacga aaaatgggta gtctccaccc tttcaccgtc taaccttagc
     1621 tgcctctctg gactgcttta aaggtttttt actattctat tatttctact agcacttgtc
     1681 aagtaaaaac atggtcacgt atgtgttgac tgctattgaa cacctcacaa gactctttcc
     1741 aaaagaatag ttaaagactt tcacttagga cagagaaaaa gagtttgctt gttacccttt
     1801 aattgaacaa atgggaattc tgttttattt tgcggatgcc tattcatctt ggcaaagggg
     1861 aagtaatgag aatgcgaatg gacttcttcg tgagtatttt cttaaaccga tttggcaaca
     1921 attaccgaaa aaatccttaa tggtgctttg ctagcttatt aatcaccgtc cccaaaaata
     1981 cttggattac aagacaggtt ttgaagcact tatagaggag atttaaaaat gttgcatttt
     2041 ttattgcaat ttatcagtta tcttatcacc caaaacttct gcaattagta tgagcactat
     2101 tgttattttt cttttttcgt acactcaaat caaaatatag caataagact attctgtaga
     2161 attgctgtca aaaagatcag ttcatttttc cttcccactt gtgtttataa tcattaaaat
     2221 aactcaatta agaaattttc tttttcctaa tagttatcgt aattaaagtt aatagaagaa
     2281 caatccaaat aagtagtgtt agattaggaa ttagagtttc attccatgaa aatccctccc
     2341 attttgtgaa aaacttagta aacagtccca taaaactata atctgttatc ttcgcaactg
     2401 tcttatccaa accagatagc atcggtaaga aagcaactaa aatcatagca ggaagactga
     2461 taacctgagc tactacttgg ctcttcgcgg ttaaacctat caataaatag aataaaatga
     2521 tggataaaga ggttagaaga acgattgtaa tataattaaa agtatgtaca attgtaactc
     2581 ctaaaataag aggagtagtt cccataatca caaaagttag caaaaaagga agaaacatcg
     2641 ttgataaaat gtattcggat cctttaacac cactcaacag aagagtttgt aaattgtact
     2701 tttctttttc ttcagacaag ataatagtta taggacttcc aacagccaaa gccaaagaaa
     2761 aaggtaaaca catcatcaaa agaactaatg cctgttgatc gttgaccttc ccctgtgttt
     2821 ccataagata tttataaaaa tatgtgaaag caaaaggcac taaaacttgc aataaaatac
     2881 tcttattgga aaggataatt tgacaacgca accataccaa agccagaaac cgtttaagca
     2941 tttagctttc ctcctgttaa tgtgataaaa atatcttcta aagtaggctc acatgaatga
     3001 attgaaaaaa tattttccag atcagcctga gatacctgtt ctagtgatgt aaaatcaaaa
     3061 gttatctgat tcccattata atctgtaacc ttaatctttt tatctttatt atatctttga
     3121 atgagttcag aaggagctcc ttgctcaact aatttccctt tatttaataa ggcaacataa
     3181 tcacataaaa gagttgcttc attcatatca tgagtcgtta gaaaaatcgt tgtccctgct
     3241 gttttcaatt ctaaaattaa ctcatgaatt gttcgagaag ttgtgggatc tagacctgag
     3301 gtcggttcat ccagaaagag tacagcgggt ttgttgataa gagctcgtgc taaaagcatt
     3361 cgttgcctca ttccagtgga taattttcct gctaccatct tgcaactatc atataatcct
     3421 actcgcttta acaaattatc aacacgtaat ttactaatat tataaaattt actataaaaa
     3481 agaagattgt tatacagaga cattttctca taaaatccac ttgtatcgct aaccaatcca
     3541 attctcttta attcaccgct tgttaaattt tgagattttt gtcccaaaat aatagattgt
     3601 cctttatcgg caaggagctg cccagtcaga atattaatcg ttgtggtctt tccagaacca
     3661 gatggtccta aaaatccaaa aatctgacct tctttaacag tgaaacttat atcatttaaa
     3721 gctattttat caccaaaact ttttgataaa tggctaactt caatcatact cattgcccct
     3781 cctttatatt ctacattttt acttaacatc tatttactta gctttatcaa ataaacgtct
     3841 taaaaaaaaa caataacatt aagcatataa ccgttagcaa gattgtttca
//
LOCUS       DAVKEV010000089         3823 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVKEV010000089 DAVKEV010000000
VERSION     DAVKEV010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3823
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.089"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            148..375
                     /locus_tag="VWZ68_002058"
     CDS             148..375
                     /locus_tag="VWZ68_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9373021.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            663..3560
                     /gene="nanA"
                     /locus_tag="VWZ68_002059"
     CDS             663..3560
                     /gene="nanA"
                     /locus_tag="VWZ68_002059"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEU9373022.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKEAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1315 a          631 c          856 g         1021 t
ORIGIN      
        1 tgaggtataa taaatttact aacacttata aaaagtgata gaatctatct ttatgtatat
       61 ttaaagatag attgctgtaa aaatagtagt agctatgcga aataacagat agagagaagg
      121 gattgaagct tagaaaaggg gaataatatg atatttaagg cattcaagac aaaaaagcag
      181 agaaaaagac aagttgaact acttttgaca gtttttttcg acagttttct gattgattta
      241 tttcttcact tatttgggat tgtccccttt aagctggata agattctgat tgtgagcttg
      301 attatatttc ccattatttc tacaagtatt tatgcttatg aaaagctatt tgaaaaagtg
      361 ttcgataagg attgagcagg aagtatggta taaatagcat aagctgatgt ccatcatttg
      421 cttataaaga gatattttag tttaattgca gcggtgtcct ggtagataaa ctagattggc
      481 aggagtctga ttggagaaag gagaggggaa aattggcacc aatttgagat agtttgttta
      541 gttcattttt gtcatttaaa tgaactgtag taaaagaaag ttaataaaag acaaactaag
      601 tgcattttct ggagtaaatg tcttatttca gaaatcggga tatagatata gagaggatca
      661 gtatgaatcg gagtgttcaa gaacgtaagt gtcgttatag cattaggaaa ctatcggtag
      721 gagcggtttc tatgattgta ggagcagtgg tatttggaac gtctcctgtt ttagctcaag
      781 aaggggcaag tgagcaacct ctggcaaatg aaactcaact ttcgggggag agctcaaccc
      841 taactgatac agaaaagagc cagccttctt cagagactga actttctggc aataagcaag
      901 aacaagaaag gaaagataag caagaagaaa aaattccaag agattactat gcacgagatt
      961 tggaaaatgt cgaaacagtg atagaaaaag aagatgttga aaccaatgct tcaaatggtc
     1021 agagagttga tttatcaagt gaactagata aactaaagaa acttgaaaac gcaacagttc
     1081 acatggagtt taagccagat gccaaggccc cagcattcta taatctcttt tctgtgtcaa
     1141 gtgctactaa aaaagatgag tacttcacta tggcagttta caataatact gctactctag
     1201 aggggcgtgg ttcggatggg aaacagtttt acaataatta caacgatgca cccttaaaag
     1261 ttaaaccagg tcagtggaat tctgtgactt tcacagttga aaaaccgaca gcagaattgc
     1321 caaatggtcg agttcgcctg tatgttaatg gtgttttatc tcgaacaagt ctgaaatctg
     1381 gcaatttcat taaagatatg ccagatgtaa cgcatgtgca aatcggagca accaagcgtg
     1441 ccaacaatac ggtttggggg tcaaatctac agattcggaa tctcactgtg tataatcgtg
     1501 ctttaacacc agaagaggta caaaaacgta gtcaactttt taaacgctca gatttagaaa
     1561 aaaaactacc tgaaggagcg gctttaacag agaaaacgga catattcgaa agcgggcgta
     1621 acggtaaacc aaataaagat ggaatcaaga gttatcgtat tccagcactt ctcaagacag
     1681 ataaaggaac tttgatcgca ggtgcagatg aacgccgtct ccattcgagt gactggggtg
     1741 atatcggtat ggtcatcaga cgtagtgaag ataatggtaa aacttggggt gaccgagtaa
     1801 ccattaccaa cttacgtgac aatccaaaag cttctgaccc atcgatcggt tcaccagtga
     1861 atatcgatat ggtgttggtt caagatcctg aaaccaaacg aatcttttct atctatgaca
     1921 tgttcccaga agggaaggga atctttggaa tgtcttcaca aaaagaagaa gcctacaaag
     1981 aaatcgatgg aaaaacctat caaatcctct atcgtgaggg agaaaaggaa gcttatacca
     2041 ttcgagaaaa tggtactgtc tatacaccag atggtaaggc gacagactat cgcgttgttg
     2101 tagatcctgt taaaccagcc tatagcgaca agggtgatct atacaagggt gaccaattac
     2161 taggaaatat ctacttcaca acaaacaaaa cttctccatt tagaattgcc aaggatagct
     2221 atctatggat gtcctacagt gatgacgacg ggaagacatg gtcagcgcct caagatatta
     2281 ctccgatggt caaagccgat tggatgaaat tcttgggtgt aggtcctgga acaggaattg
     2341 tacttcggaa tgggcctcac aagggacgga ttttgatacc ggtttatacg actaataatg
     2401 tatctcactt aaatggctcg caatcttctc gtgtcatcta ttcagatgat catggaaaaa
     2461 cttggcatgc tggagaagcg gtcaacgata accgtcaggt agacggtcaa aagatccact
     2521 cttctacgat gaacaataaa cgtgcgcaaa atacagaatc aacggtggta caactaaaca
     2581 atggagatgt taaactcttt atgcgtggtt tgactggaga tcttcaggtt gctacaagta
     2641 aagacggagg agtgacttgg gagaaggata tcaaacgtta tccacaggtt aaagatgtct
     2701 atgttcaaat gtctgctatc catacgatgc acgaaggaaa agaatacatc atcctcagta
     2761 atgcaggtgg accgaaacgt gaaaatggga tggtccactt ggcacgtgtc gaagaaaatg
     2821 gtgagttgac ttggctcaaa cacaatccaa ttcaaaaagg agagtttgcc tataattcgc
     2881 tccaagaatt aggaaatggg gagtatggca tcttgtatga acatactgaa aaaggacaaa
     2941 atgcctatac cctatcattt agaaaattta attgggaatt tttgagcaaa aatctgattt
     3001 ctcctaccga agcgaaagtg aagcgaacta gagagatggg caaaggagag atgggcaaag
     3061 gagttattgg cttggagttc gactcagaag tattggtcaa caaggctcca acccttcaat
     3121 tggcaaatgg taaaacagcg actttcctaa cccagtatga tagcaagacc ttgttgtttg
     3181 cagtagataa ggaagatatc ggacaggaaa ttattggtat agctaaagga agcatcgaaa
     3241 gtatgcataa tcttcctgta aatctagcag gtgccagagt tcctggcgga gtaaatggta
     3301 gcaaagcagc ggtgcatgaa gttccagaat ttacaggggg agttaatggt acagagccag
     3361 ctgttcatga aatcgcagag tataagggat ctgattcgct tgtaactctt actacaaaag
     3421 aagattatac ttacaaagct cctcttgctc agcaggcact tcctgaaaca ggaaacaagg
     3481 agagtgacct cctagcttca ctaggactaa cagctttctt ccttggtctg tttacgctag
     3541 ggaaaaagag agaacaataa gagaagaatt ctaaacattt gattttgtaa aaatagaagg
     3601 agatagcagg tttttaagcc tgctatcttt ttttgatgac attcaggctg atacgaaatc
     3661 ataagaggtc tgaaactact ttcagagtag tctgttctat aaaatatagt agattgaaat
     3721 aagatgtgaa caactctatc aggaaagtca aattaattta tagaaaaatt ttagcagtca
     3781 aggtgtactg ttataaattc aatatattat acgactatta acc
//
LOCUS       DAVKEV010000090         3124 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVKEV010000090 DAVKEV010000000
VERSION     DAVKEV010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3124
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.090"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            33..446
                     /gene="ndk"
                     /locus_tag="VWZ68_002060"
     CDS             33..446
                     /gene="ndk"
                     /locus_tag="VWZ68_002060"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEU9373023.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(1392..2024)
                     /locus_tag="VWZ68_002061"
     CDS             complement(1392..2024)
                     /locus_tag="VWZ68_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9373024.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLVYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(2026..2793)
                     /locus_tag="VWZ68_002062"
     CDS             complement(2026..2793)
                     /locus_tag="VWZ68_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9373025.1"
                     /translation="MSQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRISSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     IGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            complement(2844..>3124)
                     /locus_tag="VWZ68_002063"
     CDS             complement(2844..>3124)
                     /locus_tag="VWZ68_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9373026.1"
                     /translation="LNMLQLEYKNEQSWDSFIDNVNLIELEERIQTTIGIKQINTHNI
                     ITIAREGYSQNYLPNTSENTYNSLQVSLVGVLLLFISMVNILWAKKSK"
BASE COUNT          988 a          594 c          531 g         1011 t
ORIGIN      
        1 ataaaagaaa gaagctgaca aaggagacgg gtatggaaca aacattcttt atcatcaaac
       61 cagatggtgt aaaaagaggg ctagtgggtg aagtgttaaa gcgcatcgaa caacgtggat
      121 ttacaatcga aaaattggag tttcgttcac aggtttcaga agagttgatt gaccagcact
      181 atcaggactt ggttggtcag agtttttacc caccgattcg tgaattcatg acttcaggtc
      241 cagttcttgt gggtgtcatt tctggtccca aagtaatcga aacttggcgg accatgatgg
      301 gtgcaactcg tccagaagaa gctttaccag gcactattcg aggtgatttt gcaaaagctg
      361 ctggagaaaa tgagattatc caaaatgttg tacatggttc agattcagaa gagtcagcta
      421 agcgagaaat tgctctttgg ttttaagagt ggattggctc aatcaattgg ttaaaagctc
      481 atttgaatag aaagtatagt caattagttt aagacatgac gcatgatatc aaacttttta
      541 gtttttgata tggtgcgttt tttgattaag tgactattag tttgtctcgc tccgttaggt
      601 gcgagacaaa aaaaacaccc gctatgcggg tgtgcgtcga aggttatacc aaaaaaactc
      661 catacgcgat acaataaagg tgttcaatcc aattgtaaag cgaaaggaga aaaatatggc
      721 acaaaaggtt cttttatcct gttcttgttt caattgacta tatttctata ctttttcttc
      781 ctttctctgt gaaaatcgca agtttttccc accttttctc aatactgaaa caacatcttt
      841 ccagaacttc aataatttct ttttgtgtta aatcattatt taactaaatc tttggaggca
      901 atacgttttc aaagctactt ttttaccata ggttttgagc cttcaacaca gattactaag
      961 ccaaaaatgc tctaaatttt tgaaattcta acaaattcca ctcaacttta tcatcatctt
     1021 tgactttcac aatatcttcc tcaaaataac atggaataaa gatagttttc ttttaaaacg
     1081 gttgtaggag gaaaatctct cctacactat tattgattct gagagaaaat tgcaaaatat
     1141 catctaccaa actttcaatt attaagattt tttgcagttt atctgaatta gaatcgcaag
     1201 gcttctcaat aatataattg tcgaattttt tcattctaac ttcctctcca ttatttcttc
     1261 ctttatcaag aaaaagttac ctcaatatta ataaagtaca attctaaatt aagtacaatt
     1321 ctaaattaac tccaattctt gattcatgat aatatttcag taactcatcg tgcaattaaa
     1381 aacaaggatt tttatttcag atgatccatc gtgaacactt catcagccat ctcccaaatt
     1441 gccggattat gtgttgcgat aatgattagc ctattatcat ctcgaagaga tagcaaaatc
     1501 tccataatca actgagaggt tgctgggtct attgaagctg ttggctcatc tgccagaata
     1561 aagggtggat tctttaagat aatttttgcc aaggcaaccc gttgcgattc tccgcccgat
     1621 aactcaaaga tgcgcttatc taggtcaaga taaaccaggc cgacctgttc taaagcctgc
     1681 ttctgcctca accgctgttc cgaccgactc aacttttgac caatgagacc tagcttaagg
     1741 ttttcttcaa tactttggtt ttcaattaag ccaaagttct ggaagaggta gcccaattcg
     1801 tgacggaaaa aatcacttga tttataattg gccaagtctt tacctcggta aaaaatcgtc
     1861 ccatcataag gttctaattt cccaatcatg ttcatcaagg ttgtttttcc gctaccactt
     1921 gaaccaatta aggcatagac ttttccagcc tcaaatgtca ttgaaagatt cgaaaataac
     1981 tctcgttctc caaaagattt actcacctgt ttaagttcaa tcatattaac ctcccttcaa
     2041 aacaagcatg gacatcttgt tttctttctg catttggaca tgtaactgta aaagagatag
     2101 accagtaaag agtaacaaga ctaagaaagc aactcctatc tctacctgaa gaaatacact
     2161 cgcaacaaat cccagtaaaa acacacccag ttgagcaaag agataagtgc gatggatttc
     2221 taagaacctg agacctgcaa tgcgtttgat aaaaatggca cgtctaaatt cttcaaagta
     2281 gagcctattc atagtgttaa acaacaagat tgaagttgca atcccaagca cagctcctgc
     2341 tagcattacc caacgttccc tctggatatt atccaataat gtgatgtagt tgtggtaacc
     2401 tgtttgcatt tctgagaccc aattttcaat gccttgtctc tggataagct cctgggcatc
     2461 agacaattga ttaaagagaa cgtagttctg tactgcgtct atccaaaaca aaatggactg
     2521 tggaccagtt gattggggtg ttataacaat gatgattgga tctttcaaaa actgctggta
     2581 agaaataggg gtcgtattat acacaaaacg atcctgacct gattctaaat aacctaccgt
     2641 agcagtcatt tgctgtcgtt catcttgact agatatgcga ctggttaagt cgtcttcaaa
     2701 aacagattta taatgttctt cctctgaacg gaggtgttca ggcagcaata agacaaactc
     2761 ccctacatca aggtgattca tcttttgact cattttagtt gaactgtagg acttactttt
     2821 tcagagggct ccaaatttta ttttcattta ctttttttag cccataaaat atttaccata
     2881 cttataaaaa gtagtaatac tccaactaaa ctgacttgta atgaattata tgtattttct
     2941 gaagtgttag gtaaataatt ttgagagtac ccttctcggg caatagtaat aatattgtgt
     3001 gtgtttattt gtttaattcc aatagtagtt tgaattctct cttccaactc aattaaatta
     3061 acattatcta tgaaactatc ccaactttgt tcatttttat attctaattg taacatattc
     3121 aaat
//
LOCUS       DAVKEV010000091         3042 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVKEV010000091 DAVKEV010000000
VERSION     DAVKEV010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3042
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.091"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..534)
                     /locus_tag="VWZ68_002064"
     CDS             complement(<1..534)
                     /locus_tag="VWZ68_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9373027.1"
                     /translation="MENFGAVLKDIRISKNFRLKDLSCNEISESTISRFENGITKLSI
                     NHFYILLNRLGISFSEFEELVHCYYSKKECLFEELEHAVNSSDIFLLQELVDKIELKQ
                     KQEKSLCNYHIKLIAEQQINRLANLPYNSSKCNELIKYLLSVDTWMEYELKLFYNSVF
                     FMNTRTISLLYRIVIKKT"
     gene            628..1848
                     /locus_tag="VWZ68_002065"
     CDS             628..1848
                     /locus_tag="VWZ68_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="caspase family protein"
                     /protein_id="HEU9373028.1"
                     /translation="MKKILLSTVALLSLVASLLANNPVSAQESSSQATYSKSSGSWIK
                     SGNRWWYKHSDGSYTTNGWEKINGTWYYFDSEGWMKTGWIKEYGKWYYLDDSGAMKTG
                     WCLVSGSWYYLNSSGVMQTGLQTINGKQYYLAAGGAMQTGWHNIGDDTYFFANSGENQ
                     NINRRALVLGETSTRAVPIADVNAMEKVFNNQNFSEVVRFPDRTKSEIIAKMQELFES
                     SSEGDVNYLYFTCHGGRDGRIYIGSDGLAFSGWELASVLKQYKGKFVVMLDCCHAGTI
                     ISKDNTGEGNEGASTEYFDLDEFVSGFSNMDGNEKSGEMIDSKFLVLCSSRGAEYSSG
                     GSLSLATKYWSLGSGWNPLQNSQAYLAADQNNNRRITLNELYTYSREQVLKQNSNQHI
                     EVYPDNSQFVLFKK"
     gene            1861..3042
                     /locus_tag="VWZ68_002066"
     CDS             1861..3042
                     /locus_tag="VWZ68_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU9373029.1"
                     /translation="MKVSKKITLFSLSFAGFVLLTLPQAGKAFELKEDWAFKGGIRYE
                     NGKVSKINNGYEVNIKVLDLPSTSAIEWTVRLNGEKQNTNFLAEERTVSKTEDKGRFL
                     HFYIPYGYRGDIVVEAKSGNEVKTWSTKVVDDVYSDSAKSGYFILDGEQILESSWDSV
                     NESYIATLPTVTSGKTVVAWREKGTLNLIKPGRIARQYNSSGSYVELSPIFETASWLK
                     SNQNWYYQKQGQLVQNSWIKDQGSWYFMDDEGVMFNQTWLHQGGSWYAFKSSGAMISA
                     DWLYDNGSWYYLKDSGSMVTGWLKNGGSWYYLNKSGSMATGWIKDSGTWYYLKNSGSM
                     ATGWVKDSGSWYYLKNSGSMATGWVKDNGKWYYLASSGNMLRNTRTPDGYYVDGSGAW
                     K"
BASE COUNT         1026 a          421 c          623 g          972 t
ORIGIN      
        1 tgtttttttg attactattc tatatagtaa gctaatggtt ctagtattca taaaaaacac
       61 tgaattatag aaaagtttta gttcatactc catccaagta tctacagaaa gcagatattt
      121 tattaattca ttacatttag atgaattata aggaaggttt gcaagacgat taatctgttg
      181 ttcagcaatc aattttatgt gataattgca taaacttttt tcttgctttt gttttaactc
      241 tattttatcc actaattctt gaagtaaaaa tatatctgaa gaatttacag catgttctaa
      301 ttcttcaaaa agacattctt ttttggaata ataacaatga actaattctt caaattctga
      361 aaatgatatt ccaagacggt ttaacagaat ataaaaatga ttaatagata attttgtaat
      421 gccattttcg aaacgagaaa tagttgattc actaatttca ttacatgata aatctttaag
      481 gcgaaaattt tttgaaatac gaatatcctt taaaactgct ccgaaatttt ccataatgtt
      541 cctcttccat ttctgcaaaa aataaaacgc ttgtttttta tttatgatat gattatacaa
      601 aaataaaata gaaaggacaa taatatcatg aaaaaaattt tattgtcaac agttgcttta
      661 ttaagcttag tagcatctct gctagcaaat aatccagttt ctgctcaaga atcatcctct
      721 caagcaactt atagtaagtc aagtggaagt tggataaaat ctggtaaccg ttggtggtat
      781 aagcattctg atggttctta tactacaaat ggatgggaaa aaataaatgg tacctggtac
      841 tattttgata gtgaaggttg gatgaagaca ggttggatta aagaatatgg gaaatggtat
      901 tacctagatg atagtggtgc tatgaaaact ggatggtgtt tggtttctgg tagctggtat
      961 tatttaaata gtagcggtgt aatgcaaacg ggactacaga ctatcaatgg aaaacaatat
     1021 tatttagctg ccggcggtgc tatgcagaca ggttggcaca atatcggaga tgatacctat
     1081 ttctttgcta atagtgggga aaatcaaaat atcaatcgtc gtgctttagt tcttggtgaa
     1141 acatcaacga gagcagtacc tattgcagat gttaatgcta tggaaaaggt ttttaataac
     1201 caaaacttta gtgaagttgt tcgtttccca gatagaacaa aatccgagat aattgcaaaa
     1261 atgcaagagc tttttgaatc ttctagcgaa ggcgatgtga actatcttta ctttacttgt
     1321 catggaggaa gagatggaag aatctatatt ggtagtgatg gcctagcatt ttctggttgg
     1381 gaattggcgt ccgttttgaa acaatacaaa ggtaagtttg ttgttatgct ggattgttgt
     1441 catgctggaa caattatttc taaagataat acaggtgaag gcaatgaagg agcctctacg
     1501 gaatattttg atttagatga atttgtatca ggattttcta atatggatgg taacgaaaaa
     1561 tcaggtgaga tgattgactc taaattttta gtattatgct catcaagagg tgcagaatac
     1621 tctagtggtg gatcattaag tttagcgact aaatattggt ctttaggttc aggatggaat
     1681 cctctacaga attcacaagc atatttagca gcagaccaaa ataataatcg cagaatcaca
     1741 ttaaatgaat tgtatacata ctctcgtgaa caagttttga aacaaaattc taaccagcat
     1801 attgaagttt atcctgacaa cagtcaattt gtgttattta agaaataagg gggcaataaa
     1861 atgaaagtat caaaaaaaat tacactattt agtttgtctt ttgcaggttt tgttttattg
     1921 actttacctc aagcaggaaa ggcttttgaa cttaaagaag actgggcatt taaaggtggc
     1981 attcgatacg agaatgggaa agtcagcaaa attaataatg gatatgaagt aaatattaaa
     2041 gtgttagatt tacctagtac tagcgcaatc gaatggacag ttagattgaa tggagaaaag
     2101 caaaatacta acttcttagc ggaggaaaga actgtatcta aaactgaaga taagggacgt
     2161 ttcttgcact tttatatccc ctatggatat cgtggggata ttgtagtaga ggctaagagt
     2221 ggaaacgaag tgaagacttg gtctactaag gtagttgacg atgtttattc agattctgct
     2281 aagagtggct actttattct cgatggggaa caaatcttag aaagttcatg ggattccgta
     2341 aatgagtctt atattgcaac gcttccaact gtaacatcag gaaaaactgt tgttgcttgg
     2401 cgtgaaaaag gaactcttaa tttaattaaa ccaggaagaa ttgctcggca atataatagc
     2461 agtggatcat atgtagaact ttctccaatc tttgaaactg ctagttggct aaaatcaaac
     2521 caaaactggt actatcaaaa acaaggtcaa ttagttcaaa attcttggat caaggatcag
     2581 ggaagctggt actttatgga tgatgaaggg gttatgttta atcaaacatg gctacaccaa
     2641 ggtggaagct ggtatgcctt taagtcatca ggagccatga tttcagctga ttggttgtat
     2701 gataatggtt cttggtatta cctaaaggac tcaggttcta tggtaacagg atggcttaaa
     2761 aatggaggct cttggtatta cctaaacaag tcaggttcaa tggctacagg ttggattaaa
     2821 gatagtggaa cttggtatta tctaaagaat tcaggctcta tggcgacagg ctgggtgaaa
     2881 gatagtggct cttggtatta tctaaagaac tcaggttcaa tggcaacagg ttgggtcaaa
     2941 gataatggta agtggtacta tctcgcatca tctggtaata tgcttcgcaa tacacgcaca
     3001 ccagatggct attatgtaga tggcagtggc gcttggaaat aa
//
LOCUS       DAVKEV010000092         2958 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVKEV010000092 DAVKEV010000000
VERSION     DAVKEV010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2958
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.092"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(27..1382)
                     /gene="rlmD"
                     /locus_tag="VWZ68_002067"
     CDS             complement(27..1382)
                     /gene="rlmD"
                     /locus_tag="VWZ68_002067"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU9373030.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1420..2196
                     /gene="recX"
                     /locus_tag="VWZ68_002068"
     CDS             1420..2196
                     /gene="recX"
                     /locus_tag="VWZ68_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEU9373031.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDENIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2285..2818
                     /locus_tag="VWZ68_002069"
     CDS             2285..2818
                     /locus_tag="VWZ68_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEU9373032.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
BASE COUNT          951 a          540 c          532 g          935 t
ORIGIN      
        1 cttttcaaac tttgtcaact acttttttaa acttttttta ttaattttac aacagcttca
       61 gttcgagctg tatgtgggaa catatcgacc gactggatat aatgaagatc atagacttct
      121 actaagcgta ccaaatcacg agccaaggtc gaaacattac aagaaatata aaccattttt
      181 tctggtacat aagtaagaat agtatctaat aacttatcat ccagacctgt acgtggtggg
      241 tcaacaatca aagcatctgc tcggtagcct tccttgtacc aacgaggaat aatctcttct
      301 gccgttccag cttcataatg agtattgtca aatcccattc ttttagcatt tcgcttggca
      361 tcttcaatag cttctggaat aatatccata cctctgagtg tttttacttt ctttgcaaag
      421 gcaaatccaa tcgttccaac tccacaataa gcgtcaatca aatggtcttc tttatcaaca
      481 tccagcgctt ttactgcttc gctatagagg acttctgttt gctcaggatt tagttgataa
      541 aaagctcgag gggatagtga aaattcataa ttgagtacac cttcttgaat actctcttgc
      601 ccccagataa tctctgtctt ttcaccatat atctcactgg ttttagctgt atttgtatta
      661 acagctactg tcacaacttc tgggaaatct ttaaccaact cttttaccaa ttgagttaaa
      721 ttaagctggc ggtttgtaac aataataatc tgaacctgtc cggtctttct cgcgcgtcgg
      781 accataatag tacggacacc tagaactttt ctctcatccg tgattggaat ctggtgataa
      841 gtaagtaatt ctgctaagcg attagcaatc acttgggttt ccttatcttg taccaggcag
      901 tctttcaact ctactaaata gtgagagttt tgtgcatata agcccgcctt gacctgattt
      961 ttaaattttc gagtctgaaa ttgtaactta gctctgtaat attttggttc ctgcattcca
     1021 atagttggac gaatttcata attttcatat cctgcaggag caaatttttt cagcgcttga
     1081 tgaagtaagt ccgtcttgaa ctccagctgc ttatcataat gcaggtgcat gatttggcag
     1141 cctccgcatt cattataaat agtacaagat ggcacaattc gaaatttaga cttcttgttg
     1201 accttcagta attttgcttc aacaaagttg cgtctaatag aagtaatctg acaatagata
     1261 tcttcgcctt tgagagctcc aggtacaaag actaatgttt tttggtaaaa gccgattccc
     1321 tcaccattaa ttcccatgcg tttgattttt aatggtattt tttgtttcac tttcagattc
     1381 atacccctat cttatcacat tttgagttat aatagagcta tgaaaatcac aaaacttgaa
     1441 aagaaaaaaa gactctatct gatggagctt gataatggcg acaaatgcta tatcaccgaa
     1501 gatacaattg ttcgttttat gttatcgaga gataaggtga taagcgaaga ggaattgaaa
     1561 gagattcaag actttgctca attttcttat ggtaagaatc tggccctcta ccacttatcc
     1621 tttaaagcac gcactgaaaa agaagtcaga gaatatctga aaaaatacga tattgatgaa
     1681 aacatcgttt ctcaagttat tgctaatctt aaagaagata agtggattaa tgatggtcag
     1741 tacgcttatg ctatcatcaa taccaatcaa ctttcaggag acaagggtcc ttatgtgctg
     1801 actcagaaac tagctcaaaa agggatttca aaatctacta tagaagagaa cttgaaagaa
     1861 tttgattttt ctgaagttgc tcaacgtgta gccaataaac tattgaaaaa atatgaggga
     1921 aaacttccag ctcgtgccct gcaagataag attatccaga acttgactaa caagggcttc
     1981 tcttattctg atgctaaaat tgcctttgac gacttagata gccaagttga ccaagaaacg
     2041 actcaagaac tcatcttcaa ggaacttgat aagcaatata ctaagtatgc tcgaaagtat
     2101 gaaggatacg aactgaagca gcgtttaact caagttttag cacgaaaggg ctacgatttt
     2161 tcggatatag caagcgctct tagagaatat ctttaatatt tccaagtgaa attcacagat
     2221 tttaggtaat tttatggtac aatagtaaat gataaactta taaattgtag aaagttggtt
     2281 agttatgaag cttccaaaag aaggcgactt tattacaatt caaagttata agcatgatgg
     2341 gagtctccac cgaacttggc gggacaccat ggtactaaaa acaacagaaa acgccattat
     2401 tggtgtcaac gatcatacac ttgttaccga aagtgatggt cgtcgttggg tcactcgaga
     2461 accggctatt gtttactttc acaagaaata ttggtttaat atcattgcca tgattcgtga
     2521 taatggaact tcttactatt gcaatatggc tagcccctac tatctggatg aagaagcact
     2581 gaagtatatt gattacgatt tggatgttaa aatttttaca gatggggaaa aacgtctctt
     2641 ggacgttgaa gagtacgagc gtcacaaacg caaaatgaat tattctgatg acttggacta
     2701 tattttaaaa gaacatgtca aaattcttgt tgattggatt aacaatggac gtggtccttt
     2761 ctcagaagcc tatgtaaaca tttggtacaa gcgctatgta gaactaaaga atcggtaaag
     2821 ttgtcaaagg tcaggaacaa aatcctgacc tttttttggt agtataaaat aaattgtgta
     2881 aacacaaaaa ggaataaatc tattatagca gagttacaac acattactag aaagagattt
     2941 atgcaaaatt cgtaaaat
//
LOCUS       DAVKEV010000093         2942 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVKEV010000093 DAVKEV010000000
VERSION     DAVKEV010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2942
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.093"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            129..359
                     /locus_tag="VWZ68_002070"
     CDS             129..359
                     /locus_tag="VWZ68_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEU9373033.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            588..2846
                     /locus_tag="VWZ68_002071"
     CDS             588..2846
                     /locus_tag="VWZ68_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU9373034.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKTEVKSSEKEK"
BASE COUNT          937 a          608 c          599 g          798 t
ORIGIN      
        1 aaatttttta tccaatttat ttaaaaatct ttaaactagc agaattaacg agaaatctta
       61 gttttttcta gtcaagttgg cctcctttat ggtaaaatag taacgataag aaatgaagga
      121 gaatcaaaat ggaatcacat ttggttagaa tcatcaaccg ccttgaagca atggcaaacg
      181 atggcggaaa tttaaaacgt aattttgaac gcgaaggagt tgttgttgca gaagttgcgt
      241 acagccacga cgaagaaaac ggcccaatct ttacccttcg tgacgtagaa gatcgcgaaa
      301 cgtatacgtt tgatagcatt gacttaatcg caatggaaat ttacgaactt ctctactaat
      361 ctaaaacaag ctgggattgt ccctgcatgt ctaagtaaaa tcctttttgt ctcacaaata
      421 ggattttttt atagtccaaa ttcacaaaaa ttttcattgt aacaacttct caaagcttca
      481 atctttttac ttgctttaca ccccaatcct gttataatga gagtatagaa tttgactatt
      541 tttgaccttt aaacaagtca ggctaaagaa agaaatgagg tagatgtatg ctttgtcaaa
      601 actgtaaaat taacgactca acaattcatc tttacaccaa tctcaatgga aaacaaaaac
      661 aaattgacct ctgtcaaaac tgctataaga ttatcaaaac agatcctaac aatagcctct
      721 tcaaaggtat gacggatctg aacaatcgtg acttcgatcc ctttggtgat ttcttcaatg
      781 atctaaacaa tttcagacct tctagcaata ctcctcctat tcccccaacc caatcaggtg
      841 gaggttacgg tggaaacggc ggttatggtt cccaaaatcg tggatctgct caaactccgc
      901 cacctagcca agaaaaaggc ctgctggaag aatttggtat taatgtaact gaaattgccc
      961 gtcgtggaga cattgacccc gttattgggc gcgacgatga gattatccgt gtcatcgaga
     1021 ttctcaatcg tagaaccaag aataatcctg tccttatcgg tgaacctggt gtcggaaaaa
     1081 cggccgttgt cgaaggtcta gctcagaaaa ttgtcgatgg cgatgtgcca cataaactcc
     1141 aaggtaaaca agtcatccgt ctggatgtgg ttagcttagt tcaaggaacg gggattcgag
     1201 gacaatttga agaacgcatg caaaaactca tggaagaaat tcgcaaacgt gaagacatca
     1261 tcctctttat cgatgaaatc catgaaattg ttggtgctgg ttctgcgagt gatggtaata
     1321 tggacgcagg aaatatcctc aagccagccc ttgctcgtgg agaactgcaa ctagtcggtg
     1381 ctactaccct caatgaatac cgtatcattg aaaaggatgc tgccctcgag cgtcgtatgc
     1441 agcctgttaa agtcgatgaa ccaacggtgg atgaaacaat cactattctc aaagggattc
     1501 aaaagaaata cgaagattac caccacgttc aatataccga tgctgcgatt gaagcagctg
     1561 caactctttc caatcgctac atccaagatc gcttcttgcc tgacaaggcc attgacctcc
     1621 tagatgaagc tggttctaag atgaacttga ccttgaattt tgtggatcct aaagtaattg
     1681 atcagcgctt gattgaggct gaaaatctca agtctcaagc tacacgagaa gaagattttg
     1741 agaaggcggc ctacttccgc gaccagattg ccaagtataa ggaaatgcaa aagaaaaaga
     1801 tcacagacca ggatactcct atcatcagcg agaaaactat tgagcacatt atcgagcaga
     1861 aaaccaatat ccctgttggt gatttgaaag agaaagaaca atctcaactc atccatctag
     1921 ccgaagatct caagtctcat gttattggcc aagatgatgc agtcgataag attgccaagg
     1981 ctattcgccg taatcgtgtc ggacttggta cccctaaccg cccaatcgga agcttcctct
     2041 tcgttgggcc aactggtgtc ggcaagacag aactttccaa acaactggct atcgaacttt
     2101 ttggttctgc tgatagtatg attcgctttg atatgagtga atacatggaa aaacatagtg
     2161 tggctaagtt ggtcggcgct cctccaggtt atgttggcta tgatgaggct ggtcaattaa
     2221 ctgaaaaagt tcgccacaat ccatattctc tcatccttct cgatgaagtg gaaaaagctc
     2281 acccagatgt tatgcacatg tttcttcaag tcttggacga tggtcgtttg acagacgggc
     2341 aaggacgcac cgttagcttc aaggatgcta tcattatcat gacctcaaat gcaggtacag
     2401 gaaagaccga agctagcgtt ggatttggtg ctgctagaga aggacgtacc aattctgtcc
     2461 tcggtgaact cggtaacttc tttagcccag agtttatgaa ccgttttgat ggcattatcg
     2521 aatttaaggc tctcagcaag gataacctcc ttcagattgt cgagctcatg ctagcagatg
     2581 ttaacaagcg cctctctagc aacaacattc gtttggatgt aactgataag gtcaaggaaa
     2641 agttggttga cctaggttat gatccaaaaa tgggagcacg cccacttcgt cggactattc
     2701 aagactatat tgaggacaca atcactgact actaccttga aaatccaagc gaaaaagatc
     2761 tcaaagcagt tatgactagc aagggaaaca ttcagattaa atctgccaaa aaaactgaag
     2821 ttaaaagttc tgaaaaagaa aaataaatcc tataaaaaaa gagtagaaaa tgaaattttt
     2881 ctgcttcttt ttttactaaa ataactgtaa tttcttgaca gcttgccctt tgtccattat
     2941 ga
//
LOCUS       DAVKEV010000094         2830 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVKEV010000094 DAVKEV010000000
VERSION     DAVKEV010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.094"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..143)
                     /locus_tag="VWZ68_002072"
     CDS             complement(<1..143)
                     /locus_tag="VWZ68_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9373035.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     GKEA"
     gene            348..536
                     /locus_tag="VWZ68_002073"
     CDS             348..536
                     /locus_tag="VWZ68_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEU9373036.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            693..1058
                     /locus_tag="VWZ68_002074"
     CDS             693..1058
                     /locus_tag="VWZ68_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU9373037.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            1061..2728
                     /locus_tag="VWZ68_002075"
     CDS             1061..2728
                     /locus_tag="VWZ68_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEU9373038.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
BASE COUNT          901 a          516 c          624 g          789 t
ORIGIN      
        1 gcttcttttc ctttctgttg ataggctagt agcagacgat tgatttgtct ttcagaaaga
       61 ttgagttcga cacaggcccg tttctttgtt ttctttcctt gggctatagc ttttatcaca
      121 agatattttt tcgtttcatt catattcagt tggatccttt tcatatgact attctaccaa
      181 atgtgacatt ttcacgttcg atttactaaa gacattatca cattcgaatc acaacacaaa
      241 taaaaaatct tccaattccc ttgcaaaaaa caagaaagtg tgataacata gtacggtatg
      301 tggtgctagc acatccgcta tattagatct aataggagga aaacacaatg gctaaagtat
      361 gttactttac aggtcgtaag actgtatcag gaaacaaccg ttcacacgcg atgaaccaaa
      421 caaaacgtgc cgtaaaacca aaccttcaaa aagttactgt tcttatcgat ggtaaaccta
      481 aaaaagtttg ggcttcagct cgtgctttga aatcaggtaa agttgaacgc gtttaataat
      541 aaaagcaaag gagaccttag ggtctttttt cttttattgt gggtataaca tcgtttgaaa
      601 aatagagtaa atatccgctg atacatcatt ctgcttttac acttgggctg aaatatgata
      661 aaatagagta tcaactagtt gaggtaaaaa ggatgactgt aaaaattaat acaaaagatg
      721 gtcaaatcga actaacagat gaagtgattg caaccgtcgt aggtggagca gcaactgaga
      781 tttttggtgt ggtcggtatg gctagtaaaa atgccctcaa agataatttc caagccctgc
      841 taggtaagga aaattattct aaaggtgtcg tcgtaaaggc agccgaagat ggcagtattg
      901 cagttgatgt atataccgtg ttaagctacg gaacaaagat tagtgaagtg tcaaaaaaca
      961 ttcaagagcg tgttgccttt agcttggaaa accagcttgg aattactgct cagactgtaa
     1021 atgtctacat tcaaaatatc aaagttgtag gagaataacc gtgtcaaaga ttactactag
     1081 cttatttcaa gaaatggtgc aggctgcatc aactcgcttg aataagcaag ctgaatatgt
     1141 caattcatta aacgtctttc cagttccaga tggagatact gggacaaata tgggaatgac
     1201 cattgaaaat ggtgctaaag aagttgcaga caagccagct tctacagttg gagaagtagc
     1261 gagcattctt gccaaagggc ttttgatggg tgcgcgtggg aactcaggag tgattacatc
     1321 tcagcttttc cgtggatttt cccaagctat caaggataaa gacgagttaa caggtcaaga
     1381 cttggctctg gccttccaat caggtgtgga agttgcctat aaggcagtga tgaaacctgt
     1441 tgaaggaacg attttgacag tttctcgtgg agctgctatc ggtgctaaga aaaaagctga
     1501 gcaaacagat gatactgttg aagtcatgcg cgcagccttg gaaggtgcta aaacagctct
     1561 agctaaaaca ccagacatgc ttccagtatt gaaagaagtt ggcgttgtgg actcaggtgg
     1621 tcaaggattg gtcttcatct acgaaggttt cctttcagcc cttactggcg aatatattgc
     1681 atctgaggac tttgtagcga ctcctgccaa catgagtgag atgatcaatg tagagcatca
     1741 taagtctgta gctggtcacg tagcgactga ggacatcacg tttggttact gtactgaaat
     1801 catggtagct cttaagcaag gtccaaccta tgctaaagat tttgactacg atgaattccg
     1861 taactacttg gatgagcttg gggattctct cctcgttgtt aacgatgatg aaattgtcaa
     1921 agtccatgtt catacagaag atccaggact tgttatgcaa gaaggtctca aatatggtag
     1981 cttggtcaag gtaaaagttg acaatatgcg taaccaacac gaagcacagg ttgagaaaga
     2041 agctactcaa gttatcaagt cggctgaaga aaaagagtat gctttgattg ctgtggtggc
     2101 tggtaaaggt ctagcagata tcttctgttc tcaaggcgtg gattatgtta tcgaaggcgg
     2161 tcaaaccatg aacccttcaa cagaagactt tatcaaggct gttgaacagg tcaatgcccg
     2221 taacatcatc ttcttgccaa acaacaagaa catcttcatg gcagctcaat ctgcggcaga
     2281 agttttggag caaccagcag tagtggtaga ggctcgcact cttcctcaag gtatgacaag
     2341 tcttcttgcc tttgatccaa gcaagtccat tgaagaaaac caagagcgta tgacagctgc
     2401 tcttagcgat gtcgttagcg gaagcgtcac aacagccgtg cgtgatacaa cgatcgatgg
     2461 cttagaaatc catgaaaacg ataatctagg tatggtggat ggaaaaattc ttgtgtcaaa
     2521 ccctgatatg caccaaacat tgactgaaac cttgaaacat atgttggatg aagacagtga
     2581 aatcgtaacc ttctatgtcg gtgaagacgg aagcgaagaa cttgccaatg aaatcgctca
     2641 agaaatcgta gaagaattcg aagacgttga agtcgagatt caccaaggtc aacaacctgt
     2701 ttacccatac ctatttagtg tggaataaga ttaatgaagg actgagaaat cagttctttt
     2761 ttctttttta gtaaatgaaa tcggtatctt tttaataaaa acaaaaataa cattcataaa
     2821 taaacgttaa
//
LOCUS       DAVKEV010000095         2593 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVKEV010000095 DAVKEV010000000
VERSION     DAVKEV010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2593
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.095"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..448)
                     /locus_tag="VWZ68_002076"
     CDS             complement(<1..448)
                     /locus_tag="VWZ68_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9373039.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQ"
     gene            complement(462..1175)
                     /locus_tag="VWZ68_002077"
     CDS             complement(462..1175)
                     /locus_tag="VWZ68_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEU9373040.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1635..2015)
                     /locus_tag="VWZ68_002078"
     CDS             complement(1635..2015)
                     /locus_tag="VWZ68_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEU9373041.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQTQLAELEINK"
     gene            complement(2432..2584)
                     /locus_tag="VWZ68_002079"
     CDS             complement(2432..2584)
                     /locus_tag="VWZ68_002079"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9373042.1"
                     /translation="MLEKVTDSSIRQNAVETLTGLKSSLLLGTKDNNTISAEVDSLLA
                     LLKESK"
BASE COUNT          840 a          505 c          396 g          852 t
ORIGIN      
        1 cttggtgtaa aatcgctctt tttaaaggat aatactcttt aatattatta actttttgtt
       61 cgtaggcata ttttgctaca tgatctaggt atatatcaaa aaagtcatga ggaaaatctc
      121 ccatacagcc attacgattc atattgaggc tatattttcg attagtaaga taattcggaa
      181 atatatttcc tattactcta agattatcta cttgtgaatc ccttctccca atataatccc
      241 cttctttgac taatgatgga gatttccaag taaaaattaa atcgccagag aaatttttct
      301 tatcaaaaaa cttaaaaaga gattgataaa tactatttgc taattgacaa gtgtcagatg
      361 taaattcata attaacagct tcattaaaat caacttcaga catttcaatg tactcttcaa
      421 tagtaatatt agcttttttt gtagtcatta gctaatctcc tttaaaatgt gatcttttca
      481 agaatatttt tatctaaaca atccagcaag tcttggtaag aatagacttc gtaagtcggc
      541 tgggcttgtg tgtgattttc gaggtgatga ggattatacc agatagtgtc aatccccgca
      601 ttattgccac cttgaatgtc ggcggttaga gaatctccaa tcatcagcgt cttttcttta
      661 ctaaatccag caatttgctg gccaatcttt tcataaaaga gagcatccgg cttttgagtt
      721 tgcaactgtt ctgagataaa gacttgattg aaataaggtg ctagaccaga ttgagccaaa
      781 cgtcctgtct gaatggcagt aatgccattt gtcgcagcat acaagtcata atcacgctca
      841 atgaggctgt ccaagagatc atgagcgccc gatagtgttt gtccctgctg ggcgaggtaa
      901 aattggtaac gctgggcaag aaaactaccg tctttttcct gtccaaaatg agaaaataaa
      961 cgagaaaagc gcgtgttaac cagctcttgt ttactgattt tcttcagctc caagtctttc
     1021 cagagagcct tgttcatagg aacgtaataa tctttataag cctgaatatc cgcaactcct
     1081 tcttctttta gaagttgggt caaagccaca tcctcagcag catcaaaatc aagaagagtg
     1141 tggtcgaggt cgaagagtag aaatttgtag aacaatttga ggttttcctt tctgaaaatt
     1201 cattaaaaac attatatcat aaagcacctc atacaattaa ctaatttaat cacttaaaaa
     1261 aaattcgaac actttctata caactgacag ctcaaatctt tcagaataga acaatactaa
     1321 ctatcgagca cccccgtctt cataaatata tgtgtaattc tagacctaga attcctataa
     1381 actaaatgct ttcatactct tccaagtaat tgattgcctt aaattttaat ttttgaagga
     1441 ttctaaagct agaatagccc catcacaatc agttttgatt gattcacaat ttagaaacac
     1501 tatagtttca ctcctgttaa aataaaaagg aactgcataa agcaatccct ttctaatttt
     1561 gaaatcattt acttaacatt ttatagttga gataatcaat agcttaccta taaaaagagt
     1621 tatagtaaaa ttccttattt attgatttca agctccgcta actgtgtttg aataactgac
     1681 agttctgcac cagcctgcag aagagcagct gcattatagg caccttctac aattggaacc
     1741 ctgttgatga tgatactttt atcactgaaa tcagtcacca tttttaagtt cattttagca
     1801 gaacctaggt caaaaaaggc aagtaaagta tctgctggat tttcggaaac aaccctatct
     1861 acttgatcaa aactcgttcc aattcctccg ccctcggttc ctcctacata agtaatcgga
     1921 acatctttag ctactttact aatcagttca acaacacctt ctgcaatgtg tttggaatgt
     1981 gaaacgataa caagaccaat accaatactt tccatcaaac caccccagtt tctaaaatag
     2041 cagtaaagag taatcctgat gagaatgatc caggatcaat atgtccaaga aaccatatgc
     2101 tcctaagaca agagccaaca gactggtcat caataatagt attgttcttt ttttcatcat
     2161 tactccttaa ctagtgttta actgattaat tagccagtaa atagtttatc tttatttaca
     2221 ctatctgtta agatatagta aaataagaac aggacagtca aatcgatttc taacaatgtt
     2281 ttagaagtag aggtatacta ttctagtttc aatctactat attttgcaca ttttcatgaa
     2341 aaaaatgaga actagaactc acattctgct ctcatttttc gttttcccgt tctcctatcc
     2401 tgtttttagg agttagaaaa tgctgctacc tttacttact ctcctttaat aaagccaaga
     2461 gactatctac ttctgctgaa atagtgttat tatctttcgt tccgagaaga agactacttt
     2521 ttagaccagt caatgtctcc acagcatttt gtctaatact agaatctgtt actttttcta
     2581 gcaaggcctc cgc
//
LOCUS       DAVKEV010000096         2221 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVKEV010000096 DAVKEV010000000
VERSION     DAVKEV010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2221
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.096"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            40..491
                     /locus_tag="VWZ68_002080"
                     /pseudo
     CDS             40..491
                     /locus_tag="VWZ68_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            656..955
                     /locus_tag="VWZ68_002081"
     CDS             656..955
                     /locus_tag="VWZ68_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEU9373043.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            complement(1064..2221)
                     /locus_tag="VWZ68_002082"
                     /pseudo
     CDS             complement(1064..2221)
                     /locus_tag="VWZ68_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          687 a          430 c          379 g          725 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagt gaatacagac tatattactc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gaaaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact cctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tcaaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattggcta atactcttcg aaaataaaat tcaaatcacg taagcgtcgc cttaccgtac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgttataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcaactag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag acctctgttg atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataaca aaacgcatag
     1021 tagcaagagt tttgtactga ccccaaaaag ttagacaaat aatttatccg aaggatttag
     1081 ttctgtattg cacaaggcta agtcctttta gttttacctt aattcgttta ttgttgtagt
     1141 aatcaatata gtctacaata gcttgttcca attgattaag tgatttaaat gttttctcat
     1201 agccataaaa catttccgat ttcagaatcc caaagaagga ctccatcata ccgttgtctt
     1261 ggctgtttcc cttacgtgac atggatgctt gaattccctt accctcaaga aactgatgat
     1321 aagaatcgtg ttgatattgc cagccttggt cactatggag aatcgtattc tcgtagtgct
     1381 tctctgtgaa tgcctgttcc aacattgttt gtacttgttc taagttgggt gaagttgaaa
     1441 gattataggc gataatttcg ctattaaagc catctaaaac tggtgataag taaagctttt
     1501 gagtacttgc tggaatggca aattctgtca catctgtata gcactttccc attgttttag
     1561 agccttcaaa ttggccttga atgagattct ctgccttctt gccaacgtct cctttatgag
     1621 aagaatattt tcgtttctgt cgcattttag cttgtaaatt gagtactttc atcaagcctt
     1681 gaactctttt atgatttacc agataaccac gatttcttag ttctaaataa atccgacgat
     1741 aagcataatt tcccttgtgt tcgataaaaa tggattgaat ttcagcttta agctcttggt
     1801 ccttatctgt tttgtctagc tgtttcaagt gatagtagta ggtcgaacga gctagtttaa
     1861 tggattttag aagaagaact aacgaaaact cagtcattaa ttcttgaaca atttctgtct
     1921 ttcttctttc tctttttcct ccttcaatcg gagttctctt aactttttta ggatggcatt
     1981 ctccgctctc aggtactctc ccttttgttt tctcaacaat agtatacccg tttttcctgt
     2041 attgtgctag ccagttaaga agtatcgtac gacttgggag gccgtattca agagaaactc
     2101 tatctttagt ccagccttca tgtcagactt tatgaatcat ttcttgtttt aaatcaggag
     2161 aatagtaacg attttttcct tttttgacga actctattcc gtaacgatca atcaatttaa
     2221 t
//
LOCUS       DAVKEV010000097         2082 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVKEV010000097 DAVKEV010000000
VERSION     DAVKEV010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2082
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.097"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..654
                     /locus_tag="VWZ68_002083"
     CDS             <1..654
                     /locus_tag="VWZ68_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9373044.1"
                     /translation="LKGINVTIKKGETVAIVGESGSGKSTLAKILLGLLEPNIGSIEV
                     DGVEKEEIGQTLYRKIFGAVLQNSTLSYGTLRENLTFGHFVSDEELMTNLNSIGLSNV
                     VKSLPLGLETIIAEEGNNFSGGQQQMILLARCLLSKPSVVVLDEATSSLDNLSQQITT
                     SYLSEIGTTKILIAHRLDTIKSADKILVMHNGEIVEIGTHRELLELGGIYKQLYSNN"
     gene            678..>2082
                     /locus_tag="VWZ68_002084"
     CDS             678..>2082
                     /locus_tag="VWZ68_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU9373045.1"
                     /translation="MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSES
                     FSESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDI
                     VNSESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVTGGG
                     ESYKLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIIS
                     DIQDRLGHGTAVVAQIVGDDNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDG
                     NDIINLSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSN
                     QSDLLKLISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPA
                     GSTLSLSELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYK
                     LKDQPYNYMFVKKFWKKH"
BASE COUNT          782 a          255 c          390 g          655 t
ORIGIN      
        1 ttgaaaggaa taaatgttac tattaaaaaa ggagaaactg ttgctattgt tggagaatca
       61 ggttcaggta agagtacatt agctaaaatt ttattaggtt tattagaacc taatattggt
      121 tcaatagaag ttgatggagt agaaaaagaa gaaattggtc aaacattgta tagaaagatt
      181 tttggagcag tgttacaaaa ttcaacccta agttatggta ccttaagaga gaatttgaca
      241 tttggacact ttgtttcaga tgaagaatta atgacaaatc taaattcaat tggtcttagc
      301 aatgtagtta aatctttacc tcttggatta gagacaatca tcgctgaaga aggtaataac
      361 ttttctggag ggcagcagca aatgatactt ttagctcgtt gtcttttgtc gaaaccttcg
      421 gtagttgttt tggacgaagc aacaagtagt ttagataatt tatctcaaca aattacaact
      481 tcttacttaa gtgaaatcgg taccactaag attttaattg cccatcgact agatactatc
      541 aagtctgcag ataagatctt agtaatgcat aatggtgaaa ttgtagagat tgggacccat
      601 agagaacttc ttgaactagg aggcatttat aagcaattgt attcaaataa ttagtttttg
      661 attaaaaggg taaatttatg aagattatga aaaaaaaata ttggacttta gcgatattat
      721 tcttttgttt gttcaataat tctgttactg ctcaagaaat acctaaaaat cttgatggca
      781 atataactca cactcagact agcgaaagtt tttctgaatc tgatgaaaaa caggttgact
      841 attctaataa aaatcaagaa gaagtagacc aaaataaatt tcgtattcaa atcgataaga
      901 cagaattatt tgtaacaaca gataaacatt tagaaaaaaa ctgttgtaaa ttggaacttg
      961 aaccacaaat aaataacgat attgttaact ctgaaagtaa taatttacta ggcgaagata
     1021 atttagataa taaaattaag gaaaatgttt ctcatctaga taatagagga ggaaatatag
     1081 agcatgacaa agataactta gaatcgtcga ttgtaagaaa atatgaatgg gatatagata
     1141 aagttactgg tggaggcgaa agttataaat tatattctaa aagtaattct aaagtttcaa
     1201 ttgctatttt agattcagga gtcgatttac aaaatactgg attactgaaa aatctttcaa
     1261 atcactcaaa aaactatgtc cccaataaag gatatttagg aaaagaggag ggagaggaag
     1321 gaataatatc agatattcaa gatagattag gtcatggtac ggctgttgta gctcaaattg
     1381 taggggatga caatattaat ggagtaaatc ctcacgttaa tattaacgtc tatagaatat
     1441 ttggtaagtc gtcagctagt ccagattgga ttgtaaaagc aatttttgat gctgtagatg
     1501 atggcaatga tattatcaat cttagtactg gacaatattt aatgattgat ggagaatatg
     1561 aggacggaac aaatgatttt gaaacatttt tgaagtataa aaaggctatt gattacgcga
     1621 atcaaaaagg agtaattata gtagctgcat tagggaatga ctccctaaat gtatcaaatc
     1681 agtcagattt attgaaactt attagttcac gcaaaaaagt aagaaaacca ggattagtag
     1741 ttgatgttcc aagttatttc tcatctacaa tttcggtcgg aggcatagat cgcttaggta
     1801 atttatcaga ttttagcaat aaaggggatt ctgatgcaat atatgcgcct gcaggctcaa
     1861 cattatctct ttcagaatta ggacttaata actttattaa tgcagaaaaa tataaagaag
     1921 attggatttt ttcggcaaca ctaggaggat atacgtatct ttatggaaac tcatttgctg
     1981 ctcctaaagt ttctggtgcg attgcaatga ttattgataa atacaaatta aaagatcagc
     2041 cctataatta tatgtttgta aaaaaattct ggaagaaaca tt
//
LOCUS       DAVKEV010000098         1923 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVKEV010000098 DAVKEV010000000
VERSION     DAVKEV010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1923
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.098"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>1923
                     /locus_tag="VWZ68_002085"
     rRNA            <1..>1923
                     /locus_tag="VWZ68_002085"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          570 a          378 c          562 g          413 t
ORIGIN      
        1 cctgttaccc acatctgtta aggatgtgag gaggaagacg cagtgaactg aaacatctaa
       61 gtagctgcag gaagagaaag caaaagcgat tgccttagta gcggcgagcg aaacggcaga
      121 agggcaaacc gaagagttta ctcttcgggg ttgtaggact gcaatgtgga ctcaaagatt
      181 atagaagaat gatttgggaa gatcagccaa agagagtaat agcctcgtat ttaaaatagt
      241 ctttgtacct agcagtatcc tgagtacggc gggacacgtg aaatcccgtc ggaatctggg
      301 aggaccatct cccaacccta aatactccct agtgaccgat agtgaaccag taccgtgagg
      361 gaaaggtgaa aagcaccccg ggaggggagt gaaatagaac ctgaaaccgt gtgcctacaa
      421 caagttcgag cccgttaatg ggtgagagcg tgccttttgt agaatgaacc ggcgagttac
      481 gttatgatgc gaggttaagt tgaagagacg gagccgtagg gaaaccgagt ctgaataggg
      541 cgccttagta tcatgacgta gacccgaaac catgtgacct acccatgagc aggttgaagg
      601 tgcggtaaga cgcactggag gaccgaacca gggcacgttg aaaagtgctt ggatgacttg
      661 tgggtagcgg agaaattcca aacgaacttg gagatagctg gttctctccg aaatagcttt
      721 agggctagcg tcgacattag agattcttgg aggtagagca ctgtttgggt gaggggtcca
      781 tcccggatta ccaatctcag ataaactccg aatgccaatg aattatggtc ggcagtcaga
      841 ctgcgagtgc taagatccgt agtcgaaagg gaaacagccc agaccaccag ctaaggtccc
      901 aaaataattg ttaagtggaa aaggatgtgg ggttgcacag acaactagga tgttagctta
      961 gaagcagcta ttcattcaaa gagtgcgtaa tagctcacta gtcgagtgac cctgcgccga
     1021 aaatgtaccg gggctaaaac aatttaccga agctgtggat acctttatag gtatggtagg
     1081 agagcgttct atgtgtgatg aaggtatacc gtgaggagtg ctggaacgca tagaagtgag
     1141 aatgccggta tgagtagcga aagacaggtg agaatcctgt ccaccgtaag actaaggttt
     1201 ccaggggaag gctcgtccgc cctgggttag tcgggaccta aggagagacc gaaaggtgta
     1261 tccgatggac aacaggttga tattcctgta ctagagtatg tagtgatgga gggacgcagt
     1321 aggctaacta aagcagacga ttggaagagt ctgtctaagc agtgaggtgt gaattgagtc
     1381 aaatgcttaa ttctataaca ttgagctgtg atggggagcg aagtttagta gcgaagttag
     1441 tgacgtcaca ctgccaagaa aagcttctag cgtttaaaca tactctaccc gtaccgcaaa
     1501 ccgacacagg tagtcgaggc gagtagcctc aggtgagcga gagaactctc gttaaggaac
     1561 tcggcaaaat gaccccgtaa cttcgggaga aggggtgctg actttaagtc agccgcagtg
     1621 aataggccca agcaactgtt tatcaaaaac acagctctct gctaaatcgt aagatgatgt
     1681 atagggggtg acgcctgccc ggtgctggaa ggttaagagg agtgcttagc gtaagcgaag
     1741 gtatgaattg aagccccagt aaacggcggc cgtaactata acggtcctaa ggtagcgaaa
     1801 ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa tgatttgggc actgtctcaa
     1861 cgagagactc ggtgaaattt tagtacctgt gaagatgcag gttacccgcg acaggacgga
     1921 aag
//
LOCUS       DAVKEV010000099         1855 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVKEV010000099 DAVKEV010000000
VERSION     DAVKEV010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1855
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.099"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            16..88
                     /locus_tag="VWZ68_002086"
     tRNA            16..88
                     /locus_tag="VWZ68_002086"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:49..51,aa:Asp,seq:gtc)
     gene            113..185
                     /locus_tag="VWZ68_002087"
     tRNA            113..185
                     /locus_tag="VWZ68_002087"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:146..148,aa:Lys,seq:ttt)
     gene            191..272
                     /locus_tag="VWZ68_002088"
     tRNA            191..272
                     /locus_tag="VWZ68_002088"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:225..227,aa:Leu,seq:tag)
     gene            291..363
                     /locus_tag="VWZ68_002089"
     tRNA            291..363
                     /locus_tag="VWZ68_002089"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:324..326,aa:Thr,seq:tgt)
     gene            386..457
                     /locus_tag="VWZ68_002090"
     tRNA            386..457
                     /locus_tag="VWZ68_002090"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:418..420,aa:Gly,seq:gcc)
     gene            465..550
                     /locus_tag="VWZ68_002091"
     tRNA            465..550
                     /locus_tag="VWZ68_002091"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:499..501,aa:Leu,seq:taa)
     gene            560..633
                     /locus_tag="VWZ68_002092"
     tRNA            560..633
                     /locus_tag="VWZ68_002092"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:594..596,aa:Arg,seq:acg)
     gene            649..722
                     /locus_tag="VWZ68_002093"
     tRNA            649..722
                     /locus_tag="VWZ68_002093"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:683..685,aa:Pro,seq:tgg)
     gene            728..801
                     /locus_tag="VWZ68_002094"
     tRNA            728..801
                     /locus_tag="VWZ68_002094"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:762..764,aa:Met,seq:cat)
     gene            815..888
                     /locus_tag="VWZ68_002095"
     tRNA            815..888
                     /locus_tag="VWZ68_002095"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:849..851,aa:Ile,seq:cat)
     gene            899..988
                     /locus_tag="VWZ68_002096"
     tRNA            899..988
                     /locus_tag="VWZ68_002096"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:935..937,aa:Ser,seq:tga)
     gene            999..1072
                     /locus_tag="VWZ68_002097"
     tRNA            999..1072
                     /locus_tag="VWZ68_002097"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1033..1035,aa:Met,seq:cat)
     gene            1076..1148
                     /locus_tag="VWZ68_002098"
     tRNA            1076..1148
                     /locus_tag="VWZ68_002098"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1109..1111,aa:Phe,seq:gaa)
     gene            1168..1238
                     /locus_tag="VWZ68_002099"
     tRNA            1168..1238
                     /locus_tag="VWZ68_002099"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1200..1202,aa:Gly,seq:tcc)
     gene            1274..1347
                     /locus_tag="VWZ68_002100"
     tRNA            1274..1347
                     /locus_tag="VWZ68_002100"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1308..1310,aa:Ile,seq:gat)
     gene            1354..1441
                     /locus_tag="VWZ68_002101"
     tRNA            1354..1441
                     /locus_tag="VWZ68_002101"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1388..1390,aa:Ser,seq:gct)
     gene            complement(1574..>1855)
                     /locus_tag="VWZ68_002102"
     CDS             complement(1574..>1855)
                     /locus_tag="VWZ68_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9373046.1"
                     /translation="KEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYS
                     NAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT          437 a          386 c          490 g          542 t
ORIGIN      
        1 ccgttaactc ccaaaggtcc cgtagtgtag cggttatcac gtcgccctgt cacggcgaag
       61 atcgcgggtt cgattcccgt cgggaccgtt taaggtaacg caagttattt tagactcgtt
      121 agctcagttg gtagagcaat tgacttttaa tcaatgggtc actggttcga gcccagtacg
      181 ggtcatatat gcgggtttgg cggaattggc agacgcacca gatttaggat ctggcgctta
      241 acggcgtggg ggttcaagtc ccttaacccg cattaagata taacaaatga gccggcttag
      301 ctcagttggt agagcatctg atttgtaatc agagggtcgc gtgttcaagt catgtagccg
      361 gcatttttag atagaagaaa acagtgcgaa cgtagttcag tggtagaaca ccaccttgcc
      421 aaggtggggg tcgcgggttc gaatcccgtc gttcgcttag agaggccggg gtggcggaac
      481 tggcagacgc acaggactta aaatcctgcg attggtaacg atcgtaccgg ttcgattccg
      541 gtcctcggca taatatggag cacccttagc tcaactggat agagtacctg actacgaatc
      601 aggcggttag aggttcgact cctctagggt gcatttttct atttaactcg ggaagtagct
      661 cagcttggta gagtacttgg tttgggacca aggtgtcgca ggttcgaatc ctgtcttccc
      721 gattcatggc ggtgtagctc agctggctag agcgtccggt tcatacccgg gaggtcgggg
      781 gttcgatccc cttcgccgct ataatgatct tgtcggacct ttagctcagc tggttagagc
      841 tctcggctca taaccgagtg gtcgtaggtt caagtcctac aaggtccatt tgaatattgg
      901 aggattaccc aagtccggct gaagggaacg gtcttgaaaa ccgtcaggcg tgtaaaagcg
      961 tgcgtgggtt cgaatcccac atcctccttt tatattaacg cgggatggag cagctcggta
     1021 gctcgtcggg ctcataaccc gaaggtcgta ggttcaaatc ctgctcccgc aataaggctc
     1081 ggtagctcag ttggtagagc aatggattga agctccatgt gtcggcggtt cgattccgtc
     1141 tcgcgccatt ttattgatag tatttatgcg ggtgtagttt agtggtaaaa ctacagcctt
     1201 ccaagctgtt gtcgcgagtt cgattctcgt cacccgcttt gaactttgtt caaattacca
     1261 agttttttaa cttgggcgcg tagctcaggt ggttagagcg cacgcctgat aagcgtgagg
     1321 tcggtggttc gagtccactc gtgcccatta attggagaat tactcaagag gctgaagagg
     1381 acggtttgct aaatcgttag gtcgggtaac tggcgcaagg gttcgaatcc cttattctcc
     1441 gttttaatga gagtttgtaa ctctcttttt tatttttaga gacaataaag cttcagatcc
     1501 gtaaaactta attgaattac taatctgaag ttatttttag gctctttgtc aactgtagtg
     1561 ggttgaaaaa aagctaagct cgagaaagga caaattttgt cctttctttt ttgatgttca
     1621 aagcgataaa aatccttttt ttgaagtttt caaagttccg aaatccaaag gcgtttcgtt
     1681 tgataagttt gatgagatta tttgtcgctt ccagtttggc gttagaatag tgtagttgaa
     1741 gggcgttgac aatcttttct ttatctttga ggaaggtttt aaagacagtc tgaaaaatag
     1801 gatgaacctg cttcagattg tcctcaataa gcccgaaaaa tttctctggt tcctt
//
LOCUS       DAVKEV010000100         1777 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVKEV010000100 DAVKEV010000000
VERSION     DAVKEV010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1777
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.100"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(615..1595)
                     /locus_tag="VWZ68_002103"
     CDS             complement(615..1595)
                     /locus_tag="VWZ68_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEU9373047.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDDFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKKGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT          555 a          372 c          331 g          519 t
ORIGIN      
        1 tttcaaaaaa ttcttttata taataatgtc cttgaaagta gtttcagctg aacatttata
       61 gtccataaaa agaaaacaga aactcatctg tttttatact caatgaaaat caaagagcaa
      121 actaagaagc tagccgcatg atgctcaaaa cactgttttg aggttgtaga taagactgac
      181 aaagtcagct caaaacaccg ttttgaggtg gcagatagaa ctgacgaagt cagtaacata
      241 tatacggcaa ggcgaagctg acgtggtttg aagagatttt tgaaaagtat taacacctac
      301 agacaagcct aacgatagca agaactaccc tactcgatag gtatcggctt ttgctttctg
      361 aaaaaaatta ttttaagcaa tttgacaaat ctagcaacaa aaaattctat aaatataata
      421 gattgaaact agaatagtac acctctactt ctaaaacatt gttagaaatc gatttgactc
      481 tcctgatcga tttgtcctgt tcttgtttca ttttactata tttccatgat aaaacgcata
      541 gtatcaagtt ttcttaatcc cctgatacta tgcgtgtttg taatttttaa gattttgtgc
      601 ttagagtcga ctccttattt tagatattta aaaggaatct cacttccaca gagccagttg
      661 tagacttggt cattgacaaa tacattcatg gcttcgtgag catactcagg catgatgcga
      721 taggttttat cgcaggtcag acgattataa atcgcaaact gggtaatggg atagcaaaca
      781 tcgtcgtcca agcccgtaat catcttaacc tcaccttgga tacgatgggc aagatttttg
      841 acatcgatat aggcaagggt cgccatgatt tcctcctctg tttcatggaa ggggtcgtga
      901 aacttgaaat aacggaaaag ttcgtcgtaa gcctcgctag tattaccaat ctcaatcacc
      961 cgtctgaagt ctgacaagaa gggataaatg gcaactgttt tctgaattcg aggattgagc
     1021 gctgctgcaa ctagagctag agcccctcct tgtgaggcac catagctaga aagacgcttc
     1081 tcatcaacct gagacagact agcaacaatt tcgaccaact ggtaaatatc cagataaaca
     1141 tccttataaa agaggtggtc ccgaccttcc acagcaccac ggataatatg ccccttcacg
     1201 gtatttccta aaggagaacg caagccgtct tgtgagtaac ctgactggcc ccgcacatcc
     1261 atggaaacaa caccgtaacc agctacggtg aagcccagca tgtcggccca gtcccagcca
     1321 cgtcccatat aaccatgaaa atggaagatt agtggaacct tctcctcact ctttggaaga
     1381 acaatgcgtg catagacctt tcctttcttg cttccttcaa atgttaactc atagcacttg
     1441 acttgaggaa tgtggaaatc tctttcctcc aagtggtagg atggaagcgt ggaaacattt
     1501 ttcacttccc catcccagaa atcatcaaag tcttccggaa cctcatccct tcctctatag
     1561 gtcttaattt cttctagcaa agctggattt ttcatagcat gctcctttta ttttgtaatc
     1621 gttaccacaa ctgtagcata tctatgtaat caatgcaaga aagaagggta aatagaaagt
     1681 gaatttagat tctttacttt taggatgatg ggctgaaagt agttttagaa acgaaaaaag
     1741 agcatttcgc tctctcttct gtttatacta gtttttt
//
LOCUS       DAVKEV010000101         1692 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVKEV010000101 DAVKEV010000000
VERSION     DAVKEV010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.101"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..103)
                     /locus_tag="VWZ68_002104"
     rRNA            complement(<1..103)
                     /locus_tag="VWZ68_002104"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            complement(228..300)
                     /locus_tag="VWZ68_002105"
     tRNA            complement(228..300)
                     /locus_tag="VWZ68_002105"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(265..267),aa:Ala,seq:tgc)
     gene            complement(352..>1692)
                     /locus_tag="VWZ68_002106"
     rRNA            complement(352..>1692)
                     /locus_tag="VWZ68_002106"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          373 a          512 c          361 g          446 t
ORIGIN      
        1 atcatcgctt acttacagct acccaaggca tatcgtcgtt tgtcacgtcc ttcgtcggct
       61 cctagtgcca aggcatccac cgtgcgccct tattaactta accttatttt ctgacctttc
      121 agtcataaac tcttattaat actacagcgt tttcggttta ttttcttgtt actatttgat
      181 atagatattc aattttcaat gtgcattact tggtgatctc tcaccaatgg agcctagcgg
      241 gatcgaaccg ctgacctcct gcgtgcaaag caggcgctct cccagctgag ctaaggcccc
      301 acaagacctc tcaagactaa acaagaccaa tgcgcagttc cttatcctta gaaaggaggt
      361 gatccagccg caccttccga tacggctacc ttgttacgac ttcaccccaa tcatctatcc
      421 caccttaggc ggctggctcc ttacggttac ctcaccgact tcgggtgtta caaactctcg
      481 tggtgtgacg ggcggtgtgt acaaggcccg ggaacgtatt caccgcggcg tgctgatccg
      541 cgattactag cgattccgac ttcatgtagg cgagttgcag cctacaatcc gaactgagac
      601 tggctttaag agattagctt gccgtcaccg gcttgcgact cgttgtacca gccattgtag
      661 cacgtgtgta gcccaggtca taaggggcat gatgatttga cgtcatcccc accttcctcc
      721 ggtttattac cggcagtctc gctagagtgc ccaactaaat gatggcaact aacaataggg
      781 gttgcgctcg ttgcgggact taacccaaca tctcacgaca cgagctgacg acaaccatgc
      841 accacctgtc acctctgtcc cgaaggaaaa ctctatctct agagcggtca gagggatgtc
      901 aagacctggt aaggttcttc gcgttgcttc gaattaaacc acatgctcca ccgcttgtgc
      961 gggcccccgt caattccttt gagtttcaac cttgcggtcg tactccccag gcggagtgct
     1021 taatgcgtta gctacggcac taaaccccgg aaagggtcta acacctagca ctcatcgttt
     1081 acagcgtgga ctaccagggt atctaatcct gtttgctccc cacgctttcg agcctcagcg
     1141 tcagttacaa gccagagagc cgctttcgcc accggtgttc ctccatatat ctacgcattt
     1201 caccgctaca catggaattc cactctcccc tcttgcactc aagttaaaca gtttccaaag
     1261 cctactatgg ttaagccaca gcctttaact tcagacttat ctaaccgcct gcgctcgctt
     1321 tacgcccaat aaatccggac aacgctcggg acctacgtat taccgcggct gctggcacgt
     1381 agttagccgt ccctttctgg taagataccg tcacagtgtg aactttccac tctcacactc
     1441 gttcttctct tacaacagag ctttacgatc cgaaaacctt cttcactcac gcggcgttgc
     1501 tcggtcagac ttccgtccat tgccgaagat tccctactgc tgcctcccgt aggagtctgg
     1561 gccgtgtctc agtcccagtg tggccgatca ccctctcagg tcggctatgt atcgtcgcct
     1621 tggtgagccc ttaccccacc aactagctaa tacaacgcag gtccatctgg tagtgatgca
     1681 agtgcacctt tt
//
LOCUS       DAVKEV010000102         1653 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVKEV010000102 DAVKEV010000000
VERSION     DAVKEV010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1653
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.102"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(616..1608)
                     /locus_tag="VWZ68_002107"
     CDS             complement(616..1608)
                     /locus_tag="VWZ68_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9373048.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
BASE COUNT          558 a          280 c          206 g          609 t
ORIGIN      
        1 catatgattc tttctaatga gttgttttgt cgcttttcat tataggtcat atgggacttt
       61 ttttctacac aaaataggct ccataatatc tatagtggat ttacccacta caaatattat
      121 agaacccaaa aatgctctga aacactgatt tcaaggcatt ttttgttagt ttaaaattac
      181 tcccattctt cttttccaaa catacaatat atccaaaacc attcaaaata ctagattcta
      241 ttttttataa tatcactaaa tccacctaat tataggacgt tttcagattt ttagtcccgt
      301 cccagtccca gtaccggaga aatattgttt taatataata tctctttttg tcttctaagc
      361 tcttaaaagc aaaagaacaa gtaaagagtc aagacaagga taaaaagtcc atattagggc
      421 aaataaaaag ctttaagaca gatgacaaat ctaagtcaaa taagaaagac catagcaaag
      481 gtgcagagag ataaatattg gcggtcttcg gactgccttt atttttttat ccatttttca
      541 aatcaaattt attcagacta tatatgcaca tatacactta aattcatata aaaacatggc
      601 ttgtaaaaaa ttactttaat cacaataatc gcatttaaaa ttgtgatgtt tgcaagctaa
      661 attacggact tcacttggaa gttttccctt gtatctttta taatagatag aaaatttgct
      721 ggcagatgaa tatccaacag attctgctat ctcttttata ggtagttcag tgtttaaaag
      781 aagagtttca gctacattca ttctttttct ttgagtgtac tctgtaatgc tttgacaata
      841 tttttcctta aataaatttt ttaatttagt accactcatt ttagatattt tttcaagcgt
      901 gccttgattt acattcgttg caaaatgatc atctaagaat cttgctacat cttcaagtgc
      961 tttatcatca tcaatttcaa ttttatattt ttttctattt aagtatgtgt caattactat
     1021 acttatccat tcatttgcct ttgctttaaa gaaaaaatca gcggcaggag cgtccatctt
     1081 acaatttaat atttccattg ccactctttc taaggccttt gtaagtatta tttgattcgg
     1141 ttgaagcaag gttgaataaa aagattctgg attaatgtta atagatgcta aatgtttttc
     1201 tattagctct tttttaaaac caatggaaac agcaagataa caacaattct cgtgtaataa
     1261 aaaaacaaaa tcatctttta tattatcaaa atcaaaagta cataaagagt ttgcggtaat
     1321 agtttgatac ggattaaact tttctccgtt tgcactgaca atgtaacttg aataaattga
     1381 aacatagtct gacatactat aagtgctatt ttgaactact tcctctttga tataaaaatc
     1441 atgtatatcg ataatgaagc tgcctccttc ataaaaccaa tataggcctt ctgcataagt
     1501 tgaattctct tttttccaac aaaatgtatg acctgcactt gaatacttct cattgttttt
     1561 acattcatct actttcatat aatcttttac aaaatcataa tatgacataa cacactatcc
     1621 cttttagaca atattccaat tagccttatt aat
//
LOCUS       DAVKEV010000103         1478 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVKEV010000103 DAVKEV010000000
VERSION     DAVKEV010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1478
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.103"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            48..779
                     /locus_tag="VWZ68_002108"
     CDS             48..779
                     /locus_tag="VWZ68_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9373049.1"
                     /translation="MVNNVAVKVSNLSKEFLLGQDKTVSILKDISLSVNYGEFVSILG
                     VSGSGKSTLLSCLSSLSEPTSGEVVINGVNPYTLKEGKLAKFRRQDIAIIFQNYNLVP
                     ALPVLENVTLPLRLSGKSVDSNKVKKMLDSLNFKAELSSLVATLSGGEQQKVAITRAI
                     IADSKIIFADEPTGALDSVSRKLIFETLRNLASQGKCVLMVTHDIELASKTDRALILK
                     DGKISRQIIKPSADELYQALESSKD"
     gene            797..>1478
                     /locus_tag="VWZ68_002109"
     CDS             797..>1478
                     /locus_tag="VWZ68_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-carotene 15,15'-monooxygenase"
                     /protein_id="HEU9373050.1"
                     /translation="MLKLIIYQFQYSKRQWLGTIPLLFVSSLIVGTSLFGIASSIKTA
                     NINASQLFQMLIIFGGTTLFFLISNNIRLLIDIFKKDYQLWTILGASRTQLSLLVSGQ
                     FYLMAVIVSSIGTILSFIMADSYYKFLQNLLGRDELPDLVITANIQSILLSIFIVPTI
                     VGIGAYFYSSRILKISSILKPKKKKRKVTVTGFVNISVRLFLWLLCIGSIVSAGFIRN
                     KEIIEKQSS"
BASE COUNT          515 a          216 c          252 g          495 t
ORIGIN      
        1 attgtataat taaatcaaag atgacactgg aatcaggagg atttattatg gttaataatg
       61 tagctgttaa agtctcaaac ctttcaaaag aatttttgtt agggcaagac aaaactgtct
      121 ctattttgaa agatatttcc ttatctgtca attatgggga atttgtatca atacttggtg
      181 tcagtggttc tggaaagtct actttgctaa gttgcttatc aagtttatct gaaccaacaa
      241 gtggcgaagt tgttatcaat ggtgtaaatc catatacctt aaaagaaggg aagcttgcta
      301 aatttagaag acaagatatt gcaataattt ttcaaaacta taatctggta cctgctctac
      361 ctgtactaga aaatgttaca cttcctctga gactatcagg aaagagtgtt gatagcaata
      421 aagtaaaaaa aatgttggat agtttgaatt ttaaagcaga actatcatca ttagttgcta
      481 ccttatcagg tggagaacag caaaaagtgg ctattactcg tgcaataata gctgatagta
      541 aaattatttt tgctgatgag ccaacaggag ctctggacag cgtctcaaga aaacttatat
      601 ttgaaacact tcgtaattta gcgagtcaag gaaaatgtgt tcttatggtc actcatgata
      661 ttgagttggc ttcaaaaact gacagagcac tcattttaaa agacggaaaa atatctcgac
      721 aaattattaa accttcagct gatgagctct accaagcact tgaaagtagt aaagattaat
      781 ttgaggagga tttattatgc taaaattaat catttaccaa tttcagtact caaaaagaca
      841 atggttagga acaataccat tactatttgt atctagcctg attgttggaa catctttatt
      901 tggtattgct agttcaatca agactgctaa tattaacgct tcacaacttt ttcaaatgct
      961 aataattttt ggcgggacta ctctattttt ccttatttca aataatataa gactgctaat
     1021 agatatcttt aaaaaggatt accaattatg gactatctta ggcgcaagca gaactcagct
     1081 atctttatta gtatctggac agttttattt aatggcagtg attgttagta gtattggtac
     1141 aatactttca tttatcatgg cagatagtta ttacaaattt ttacaaaatt tattaggaag
     1201 agatgagtta cctgatttag ttattacagc caacattcaa tcaattttat tgagtatttt
     1261 tatagtccca acaattgtcg ggataggggc ttacttttat tcaagtcgaa tacttaaaat
     1321 atcatcaata ttaaaaccaa aaaagaaaaa aagaaaagtt acagtaactg gatttgttaa
     1381 catctctgtt cgtttattcc tatggctact atgtataggt tctattgttt cagcaggttt
     1441 tatcagaaac aaagaaataa ttgaaaaaca gtcaagca
//
LOCUS       DAVKEV010000104         1430 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVKEV010000104 DAVKEV010000000
VERSION     DAVKEV010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1430
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.104"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..647
                     /locus_tag="VWZ68_002110"
                     /pseudo
     CDS             1..647
                     /locus_tag="VWZ68_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(682..1430)
                     /locus_tag="VWZ68_002111"
                     /pseudo
     CDS             complement(682..1430)
                     /locus_tag="VWZ68_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          440 a          244 c          289 g          457 t
ORIGIN      
        1 ctatcttact gacaatccag acgcttattt gactgaaata gcttctgaat ttggctgtca
       61 tccaactacc atccactatg cgctcaaagc tatgggctac actcgaaaaa aagaaccaca
      121 cctactatga acaagaccca gaaaaagtag ccttatttct taaaaatttt aatagtttaa
      181 agcacctagc acctgtttat attgatgaaa caggattcga tacttatttt tatcgagaat
      241 atggtcgctc attaaaaggt cagttaataa gaggtaaagt atctggaaga agatatcaga
      301 ggatttcttt ggttgcaggt ctaacaaatg gtgagttaat cgctccaatg acttacgaag
      361 agatggtgac gagcgacttt tttgaagctt ggtttcagaa gtttctctta ccaacattaa
      421 ccacaccatc ggttattatt atggataatg caagattcca tagaatgggt aagttagaac
      481 ttttatgcga ggagtttggg cataaacttt tacctcttcc tccctactca cctgagtaca
      541 atcctattga gaaaacatgg gcttatatca aaaagaacct caaaaaggta ttaccaagtt
      601 gcaatacctt ttacgaggct cttttctctt gttcttgttt caattgacta tattagaggc
      661 gagacatttt tcggttcttt gtcaactgta gtgggttgaa gaaagcgaag atctagaaag
      721 gacaaatttc gtcctttctt ttttgaagtt ttcaaagttc ctaaaaccaa aggcattgtg
      781 cttgataagt ttgatgagat tattggtggc ttccagtttg gcgttggaat aaggtaattg
      841 aagggcgttg acgattttct ctttatcttt gaggaaggtt ttaaacagag tctgaaaaag
      901 aggtggaaaa gcaagagctg atagagatta tagctgatag agattatagt ggtgtttcaa
      961 gtcttcgaat agctcaaaag tttatctaga atttctttat tagtcaagtg catacgaaaa
     1021 gtagggcgat aaaatcgttt atcactcagt ttctgactat cttgttgaat gagctccagt
     1081 agcgcttgat agccttgtat tcatgggatt tcggatgatg gcttgtgttc tgctctcaag
     1141 aacagttatg atattgagct tatcaaagtc ctgagcaata aagctcatct ctatctcccg
     1201 attgaaacag tcactcccca gactgtttca acgtcctagg acataatctc aggaagacgc
     1261 gaaaaatcat gctcaaagtg aaaatcattg atcttgcgaa tgacagttga agttgaaata
     1321 gacaactgat gatcaatgtc ggtcatagaa atcttttcaa ttaacttttg agcaatcttt
     1381 tggttgataa tacgagggat ttggtgattc ttcttgacga tagaagtttc
//
LOCUS       DAVKEV010000105         1387 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVKEV010000105 DAVKEV010000000
VERSION     DAVKEV010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1387
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.105"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..272
                     /locus_tag="VWZ68_002112"
     CDS             <1..272
                     /locus_tag="VWZ68_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HEU9373051.1"
                     /translation="EESIKQLQNQKRQLKKKLNEQERKARNKRLIEKGAVFESIFEES
                     IDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKDEIT"
     gene            582..>1387
                     /locus_tag="VWZ68_002113"
     CDS             582..>1387
                     /locus_tag="VWZ68_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HEU9373052.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDRSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKVLNKNGKPKTRKVELTTWNDTGNVEQWRENFSDLCNKYLERAGAEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNQLVKTI"
BASE COUNT          652 a          178 c          243 g          314 t
ORIGIN      
        1 aagaagaaag cattaagcaa ttacaaaatc aaaaaagaca gttgaagaaa aaacttaatg
       61 aacaagaaag aaaagcaaga aacaaaagac ttatagaaaa aggtgcagtg tttgaaagta
      121 tttttgaaga aagtattgat ttaacaaaag atgaatttta taagttaata aaaacgttaa
      181 atgatgaaga aataagatta aacataatgg aaattttaga agaaagaata gatgataatg
      241 tagaaaaatc atctaaagat gaaataacat aattgtccct tggttacaag ggcgcaatta
      301 tacaccctaa agggtgcttg cgtcctgcgg agtcaaaccc ttgcagggag caacaaccat
      361 tcgcttttta aaagtcaagg gtaaataaac tcgctaaggc tcgcccttga cttttaaaat
      421 ttgaaatgaa agtaacaatt aagccgacat actgaaacaa caaaaattaa ttcagtagtc
      481 ggcttttttt attctatcat ttcaaaacgc tcattcacaa agaggatata aaaaaactat
      541 taagcctcca cctaaaacaa caaagaaagg aagtgataaa aatggcagac agttttcatt
      601 tttcagtaaa cataatatca agaggaaaag gcaaaagtgc agtagcaagt gcagcatata
      661 taagtggaga aaaaataaaa aatgaatggg acggagtaac ccatgactac acaagaaaag
      721 aaaaaatatt agtaaaaaat ataatattgc ctgatcatat accaaaagaa tttaatgata
      781 ggtctacctt atggaataaa gtagaaatgg cagaaaaaaa ttctaatgca caactagcaa
      841 gacaattcat aataggacta ccaaaagagt tatctttaag tgaaaataaa aacctggttg
      901 aaagatatat aaaagaaaat ttaacatcac aaggaatgat agtagattat gcaattcatg
      961 atgagagtca agataaaaat ggaaatatcc attgtcatat aatgaccata atgcgaccaa
     1021 taaacgaaaa aggagagttc ttagccaagt caaaaaaaga atatatccta gatgaaaaag
     1081 gagaaaaagt attaaacaaa aatggaaaac caaagacaag aaaagtagaa ctaacaacct
     1141 ggaacgatac aggcaatgta gaacaatgga gagaaaattt ttcagatctt tgtaacaaat
     1201 atttagaaag agcaggagca gaaaaaagag tagaccatag gagttttaaa agacaaaatt
     1261 cagattatct accgacaatc catttaggat cagcagcaag tgcaatggaa agaaagggaa
     1321 tagaaactga caagggaaac tataatagag aaataagaaa atataatcaa cttgtaaaaa
     1381 caataaa
//
LOCUS       DAVKEV010000106         1335 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVKEV010000106 DAVKEV010000000
VERSION     DAVKEV010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1335
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.106"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            237..577
                     /gene="tnpB"
                     /locus_tag="VWZ68_002114"
                     /pseudo
     CDS             237..577
                     /gene="tnpB"
                     /locus_tag="VWZ68_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(610..1335)
                     /locus_tag="VWZ68_002115"
                     /pseudo
     CDS             complement(610..1335)
                     /locus_tag="VWZ68_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          405 a          272 c          239 g          419 t
ORIGIN      
        1 aacaccccaa aagttagatt ttttctgtct aactttttgg aaggcagttc attctacacc
       61 cactattatg cgtttttatc attttgaaat ctactgctaa tcaatgaaga agcaaagatc
      121 aaactaggca gctagttaca agttacgtaa gcgcgtcata acaaggtatc tatcctaatt
      181 ccccaacttc cagtatacta gataaaaaat aattatcgga ggaaaggtat tgtactatga
      241 taattcaact aagtgattta ggtcaagttc accttgtttg tagcaagata gatatgaggc
      301 agggaataga ctcattagcc tatgtagtta aaacccactt tgaattggat cctttctccg
      361 gtcaagtctt tctcttttgt ggtggacgta aagaccgctt taaagccctt tactgggatg
      421 gtcaaggatt ttggctacta tataaacgct ttgagaacgg cagactgact tggcccaata
      481 cagaaaagga tgtcaaagct ctcacacctg aacaagtaga ctggcttatg acgggctttt
      541 ctatcactcc aaaaataaat ccatcagaaa gtcgtgattt ctattgaaat gaggactttc
      601 tttttatact catctgcttt caaaaagcat tctattccat ctccgattaa cgatggactt
      661 tatcacctcc ttctccagtc cttgtataac atcttggagt tgattcatga catcttccaa
      721 agttcgaaag gctttattct taaatccacg tttacgaatc tctttcaaca attgttcaat
      781 ggggttcatc tctggtgtgt atggaggaat aaatgcaaag ccaatattag tcggaatctt
      841 taaggtactt gatttatgcc atacagcatt gtccataacg agtaaaagat aatcatctgg
      901 ataagcttgt gaaagctctt ctaaaaaggc gttcatccac tcagtattac atccaccagc
      961 tattaagaaa aatgattcgc ctgtataggc atcaacagct ccataacaat agcgaaattc
     1021 tcgtatatag tgactatgga catgtagacc tactcctatt ggagaccaac aagatcccag
     1081 tttactgatt ctaccgaaac cagcctcatc ttggtacatc aagcaaacct tatgaaaacg
     1141 tctactggtt ttaaagcgct ttcttttctt cttgaattga gattttattt ttagacgcga
     1201 caatggtttg agcgtctgct ttcttaggat gttctggacg tggcataata tttcgccaac
     1261 catggcgctt caacagttga tagaaggcat cacgtgtgta ggaacgacct aactcctttt
     1321 tataagcctg aaata
//
LOCUS       DAVKEV010000107         1312 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVKEV010000107 DAVKEV010000000
VERSION     DAVKEV010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1312
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.107"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..160
                     /locus_tag="VWZ68_002116"
     CDS             <1..160
                     /locus_tag="VWZ68_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9373053.1"
                     /translation="ELGIDLSIEIDKLIKQGEKPSVIAQIKKFQDQVNKDNEYREMMK
                     NKKMDQER"
     gene            234..407
                     /locus_tag="VWZ68_002117"
     CDS             234..407
                     /locus_tag="VWZ68_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9373054.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            593..1120
                     /locus_tag="VWZ68_002118"
     CDS             593..1120
                     /locus_tag="VWZ68_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEU9373055.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            1247..>1312
                     /locus_tag="VWZ68_002119"
     CDS             1247..>1312
                     /locus_tag="VWZ68_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEU9373056.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRI"
BASE COUNT          693 a          176 c          204 g          239 t
ORIGIN      
        1 agaacttggt atagatttat ccatagaaat agataagcta ataaaacagg gagaaaaacc
       61 aagtgtaata gcacagatta aaaagttcca agaccaagtc aataaagata atgaatacag
      121 agaaatgatg aaaaacaaga aaatggatca agaaagataa gacctggtaa aaatatctta
      181 tccaagctat aatatgacca aacaactaaa gtcagatcta ggaggtaata gagatgaata
      241 aaaggcaaga gctaatagat gaactcataa aagcaaatga agatggaaca tacaaaacct
      301 ataaaagcac agaagaaata aaagcaatga acaatgaaga aatacagatt atatattcca
      361 acatgaaaaa ctatctatca gacaaaagaa cacacataaa ctattaaagg tggaaaggta
      421 gtgtaagcta tttttaaaag tataaaaggt acaaagacct aagaaatata taaaaacatc
      481 aaaataaagt attccaccac caagaacaat aaaataaaaa caagcaaagg gaagtataga
      541 aaaattaaaa cctatacttc ccttttttaa ttcaaacaaa ggagagaaaa gcatgataaa
      601 cgaagaaata agcaaggaag caggtcaagc agcacaaacc ataatatcat acacaataaa
      661 ggcaacaaaa gaatcaatca atttagaaaa agaaataaga aaaaagatga atgaaacttt
      721 agaaaaagca aatggaaact taaaaagtct tatgggcgat gaaatgaaaa taaaagatct
      781 ctacaagaaa ggacaactag aaaatataag catagatcaa atcgacctca aagacttaaa
      841 aaaagaacta aacaaacttg gagtaagttt ctcagtaatg aaaaacaaag aaagcaaaaa
      901 ctatgaaata ttcttccaag ccaaagacat aaaagtaatg gaatatgcct ttaagcaagt
      961 catagccaag gaaaataaaa aagaaaaaga aagtatccta aaacaaataa agaaatacaa
     1021 agacctatcc aaaaacaaag ataagacaaa agaaaaagga aaaaggaaag taaaagaaaa
     1081 agtaaaacca aacaaaaaag atatgaccag agaaatctaa agggagtaac gaaaagttac
     1141 acccttaaat aaccataata acaagacttc cgaaaaacag aagtccagaa ttccgaaaat
     1201 cggaaatcaa gaatttcgat tatcgaaaat caagaaagga gcagatatgg caacaaacaa
     1261 aagatactat tggataaaat taaaagaaga atttttcaca gacaaaagga ta
//
LOCUS       DAVKEV010000108         1301 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVKEV010000108 DAVKEV010000000
VERSION     DAVKEV010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1301
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.108"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..213)
                     /locus_tag="VWZ68_002120"
     CDS             complement(<1..213)
                     /locus_tag="VWZ68_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9373057.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     GKEAFRHGHGNRNRKPKHAIPDEIKER"
     gene            377..529
                     /gene="rpmG"
                     /locus_tag="VWZ68_002121"
     CDS             377..529
                     /gene="rpmG"
                     /locus_tag="VWZ68_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU9373058.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            539..715
                     /gene="secE"
                     /locus_tag="VWZ68_002122"
     CDS             539..715
                     /gene="secE"
                     /locus_tag="VWZ68_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEU9373059.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            770..>1301
                     /gene="nusG"
                     /locus_tag="VWZ68_002123"
     CDS             770..>1301
                     /gene="nusG"
                     /locus_tag="VWZ68_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEU9373060.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT          410 a          204 c          258 g          429 t
ORIGIN      
        1 acgttctttg atttcatcag ggattgcatg ttttggtttt cgatttctgt ttccgtgtcc
       61 gtgtctgaag gcttcttttc ctttctgttg ataggctagt aacagacgat tgatttgtct
      121 ttcagaaaga ttgagttcga cacaggcccg tttctttgtt ttctttcctt gggctatagc
      181 ttttatcaca agatattttt tcgtttcatt catattcagt tggatccttt tcatatgact
      241 attctaccaa atgggacatt ttcacgttcg atttactaaa gacattatca cattcgaatc
      301 acaatagtca atctatttcg ctaagatgct tgtcaaagcc tagctttctt gttataatgg
      361 ataagatgga ggcgttatgg cactaaaaaa agcaagccta gcttgtgcgg tttgtggttc
      421 gagaaactat tcaatcaaga tcagcggaaa ccccaagcct acacgactag aagtaaataa
      481 attttgtaag cattgtggca agtacactac acacagagaa acgagatagg agagagcgat
      541 gcgttttatt ggagatattt ttagacttct taaagacaca acgtggccaa ctcgcaagga
      601 aagctggaga gattttcgtt ctatcatgga atacacagct ttctttgtag taattattta
      661 catttttgac cagttgattg tttcaggttt gattcgattt attaacattt tttagaagat
      721 tagtggagtt aattacacta gaaatcttct atttatgaaa ggaaatatca tggatagttt
      781 tgataaaggg tggtttgttt tacaaactta ttctggttat gaaaataagg tgaaagaaaa
      841 tctattacaa cgtgcacaaa cctacaatat gttggataat attctacgcg ttgaaattcc
      901 aacacaaaca gtgcaagttg aaaaaaatgg aaagagaaaa gaagtagaag aaaatcgctt
      961 tccaggttat gttcttgtag aaatggtcat gacagatgaa gcttggtttg ttgttcgaaa
     1021 cacaccaaat gttacaggat ttgtcggatc acacgggaac agatcaaaac caactccatt
     1081 attggaacaa gaaattcgtg acattttggt atctatggga caaactgttc aagaatttga
     1141 tttcgatgtt gagattggtc aaactgtacg tattattgat ggtgcttttg cagactacac
     1201 tggtaagatt acagaaattg ataataacaa agtgaaaatg attatctcta tgtttggtaa
     1261 tgacacagtt gcagaagtaa acctaaacca aatcgcagaa t
//
LOCUS       DAVKEV010000109         1259 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVKEV010000109 DAVKEV010000000
VERSION     DAVKEV010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1259
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.109"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            3..287
                     /locus_tag="VWZ68_002124"
     CDS             3..287
                     /locus_tag="VWZ68_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9373061.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDIEKL
                     LDSKELTHFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            280..837
                     /locus_tag="VWZ68_002125"
     CDS             280..837
                     /locus_tag="VWZ68_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEU9373062.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVGGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNTHEELWLNNHVANMNKQPPLSLCESLYSFENLTVL
                     VVPIEYVLGMKMMSIREQDLKDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVLLEG
                     FSYAYGMDWLEKFFKENQDKLREFY"
BASE COUNT          439 a          208 c          213 g          399 t
ORIGIN      
        1 caatggattg gtacgattat atgatacagg catccaaaca atcacaattc aacgcaagcc
       61 attggtttcg ctatttgcga aaagttattt ttgaagacta ttcttattta acaaaccaag
      121 atatagaaaa gttgctagac tccaaagaac taacccattt tcaaaaaatt agcttgaagt
      181 atgcctttca agagcatact ccaactcata aatatgtgat ttcattaaat aaacctgcta
      241 agttaaccaa tgttcaaaaa ttgatggaga aatacaagca tggataaaat gaaaccggtc
      301 ttccaagcac taaataagga attaattcag gaaaatctga ctttaacaat tatctgtgtc
      361 ggtggttatg tcttagaata tcatggtttg cgtgccacac aagatgttga tgctttttat
      421 gaccaaaatc agaaaatcaa tgaaattatt gctcgtgtag gaaaacagtt taatcttaac
      481 acccacgaag agttatggct caacaatcat gttgcaaata tgaacaaaca acctccctta
      541 agtttatgcg aatccttgta ctcatttgag aatctgaccg ttttagtagt ccctattgag
      601 tatgtgttag gaatgaagat gatgagtatc agagagcagg atttgaaaga tattggtgca
      661 attattaaat acaaaaactt tcattcacca ttcgatacct ttaaatattt aaaagacatg
      721 ggatttgata ctattgacct ctctgttcta ttagaaggtt ttagttatgc ttatggtatg
      781 gattggttag aaaaattttt taaagaaaat caagataaac ttcgcgaatt ttattaacag
      841 tatcaaacaa gatgattgtc aattagccag tcgtcttgtt tttatgatga aatgaaataa
      901 aatcggaaca aatcacttag agaattccag tcaatttcta gcactgtttg agacgtttca
      961 gcggactata gcaaaatgaa ataagaatag gacaaatcga tcaggacagt caaatcgatt
     1021 tctaagaatg ttttagaagt aaaggtgtac tattctactt tcaatctatt atatttcaga
     1081 ttcggtccac tattccttcc caaaaacatt gcatattgcg ccgaaggaat tgctcatact
     1141 atcccaagca caaaaccctc agtcgtttga ccgagggttc ctttttatta ttcaagaact
     1201 tgaggctcta taatatttgt agtgggtaaa tcccctatgg atattatgga gcctatttt
//
LOCUS       DAVKEV010000110         1172 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVKEV010000110 DAVKEV010000000
VERSION     DAVKEV010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1172
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.110"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(40..756)
                     /locus_tag="VWZ68_002126"
     CDS             complement(40..756)
                     /locus_tag="VWZ68_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9373063.1"
                     /translation="MKKYFISGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNGATWREEALKELPDYFNTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(760..1071)
                     /locus_tag="VWZ68_002127"
     CDS             complement(760..1071)
                     /locus_tag="VWZ68_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9373064.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
BASE COUNT          350 a          231 c          168 g          423 t
ORIGIN      
        1 agattttcat cttataccat ttccagcaat acaagtagct catagaaaat aagcgagcca
       61 ctcattcatt agactagcga tttctttagg tgcttgagta taaagctcat ggccaaagtt
      121 ttctaaaaaa atagtattaa aatagtctgg caattctttt agggcttcct ctctccatgt
      181 agctccatta ggatagcgag gactaataaa caaggtatct cccacttctc tcttaaaagc
      241 ttgtattttt ctccgtaggc ggagtatcgc ttctatattt tcataattta tagccaactc
      301 atatctatta tactcaacat tccagtgata ggactgtctt acagctttct ccatattttc
      361 tgaccaatgc tttgcttcgg acttctcttt agaaataaga agagctaagt ccgaaacaat
      421 ttgagatttg atataatttt tagtttcctc taactctgta tccaaaggta aaatcttatc
      481 taaatctaga tagccaccat ccaaaagaat cagtttcttt acttcttcaa attccgatgc
      541 gaaataacga gctaaatctc ctccaagaga atggcctatc agacagatag attcttcctc
      601 tacaatctca tttttaaacc atgatttcaa ttctgtttca tctcgaagat gcttttcata
      661 tggatttaga aaatagacct gcgaatctag ttcttgaaaa aaatccttgc tatgataggc
      721 attgcttccc aaaccgctaa taaaatattt tttcattctc tacttaatac tatgcttatt
      781 catcttttgt tcaaagatag ttgtgataat ctgacgcaat tcttcgcgtt ctttttctgg
      841 aatctcacca cttgtttgag ctacagcgta gagttcaggg tattcaattg aaatgcgttt
      901 aatcgtacgt gttgtagcat gttttctgac aaaaaacggg attcgcttaa tcaagtcttg
      961 tggtactagc gccagaatct tctcagtagt ttctttgtca ctaatattag acattgtaag
     1021 ccttttctta atcatttcct gttctttttc tgtaaaatct tttaattcca ttcgattagt
     1081 cctcctattt tctctaagtt aaattatgta ctaatacaga tgaaactaca aagaataaac
     1141 tttaagaaat cttctcactg ataagatttt ag
//
LOCUS       DAVKEV010000111         1058 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVKEV010000111 DAVKEV010000000
VERSION     DAVKEV010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1058
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.111"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..559
                     /locus_tag="VWZ68_002128"
     CDS             <1..559
                     /locus_tag="VWZ68_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9373065.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIIFKVDLLFQKVSQLFE"
     gene            complement(513..>1058)
                     /locus_tag="VWZ68_002129"
     CDS             complement(513..>1058)
                     /locus_tag="VWZ68_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9373066.1"
                     /translation="IPMNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKP
                     LEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGF
                     IFQLTPFESSEIISKFLLFNLSSPLFYKQLKALTKLSGQALYNIPKTTLSELLIPLAP
                     FEEQELITQKVEKLFEKVNQL"
BASE COUNT          381 a          168 c          155 g          354 t
ORIGIN      
        1 gaacaaagac gaaacaacct cttatcctat atatgaaatc ccagaagcat ggagatatat
       61 taaatttgct agcctagtta acttcagaat aggaaaaact cctccacgca gtgaagctac
      121 tttttgggga actgaaatac cttgggtatc tatatcagat atgcctatat ctggttatgt
      181 aactaatacg agagaatcta tttctaaatt agcattaaaa tcaaagaaaa tagacatttc
      241 acctaaagga actttattaa tgagttttaa attatctatt ggaaaagttg ccatattgga
      301 tattcctgcc actcataatg aagccattat atcgatattc ccctatgcta ataaagaaaa
      361 tattatcaga gattacttaa tgatattttt gccacttatc tctactttag gtgattcaaa
      421 agatgctatc aaagggaaaa cattaaatag taccagtatc tccgaattat taatccctat
      481 ttctaatcat gaagagatga aaagaatcat tttcaaagtt gatttacttt ttcaaaaagt
      541 ttctcaactt tttgagtaat aagttcctgt tcctcaaaag gagctaacgg aattaatagc
      601 tcgctcagtg tagttttagg aatattatat aaagcttgac ctgatagttt agttaatgct
      661 ttcaattgtt tataaaataa cggagaggac aagttaaata atagaaattt tgaaataatc
      721 tctgaacttt cgaatggtgt taattggaaa ataaatccac cagccacaac accatcatag
      781 tctttatcga ttcttgcaaa ctttccaata tgttctaaag aggttgatac aggtgttatt
      841 agctgattat gttttaaata aacttgctca gaggagatga attgtgtatc aatgtagtaa
      901 tcgttatcca acagagaaaa ttctaaaggc ttaatattac caccacgtat aattctaaca
      961 cctttattat taatgcttaa atcgcccttc ttgtaagaaa gacctgtatt cattgaaaaa
     1021 atatctttta tttttataac aacccaattc ataggtat
//
LOCUS       DAVKEV010000112          998 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVKEV010000112 DAVKEV010000000
VERSION     DAVKEV010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..998
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.112"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>998
                     /locus_tag="VWZ68_002130"
     CDS             <1..>998
                     /locus_tag="VWZ68_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU9373067.1"
                     /translation="KLLDIKDPNIQILDIIKKDTHKEIIAKLDYDAPSCPECGNQLKK
                     YDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQIPRIINQKI
                     AQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYAFTKGKMSF
                     IAQDFNNLNIITVLKGRTQAVIRNHFLKYDRAVRCRVKIITMDMFSPYYDLARQLFPC
                     AKIVLDRFHIVQHLSRAMSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDSRKLSDKRF
                     YRPTFRMHLTNKEILDKLLSYSQDLKHHYQLYQLLLFHFQNKKPEKFFGLIEDNLK"
BASE COUNT          323 a          213 c          164 g          298 t
ORIGIN      
        1 aaaattacta gacattaaag accctaatat ccagatttta gacatcatca agaaggatac
       61 acacaaggaa atcatcgcca aactggacta cgacgcccca tcttgccctg agtgcggaaa
      121 ccaattgaag aaatatgact ttcaaaaacc ttctaaaatt ccttatcttg aaacgactgg
      181 tatgcctact agaattctcc ttagaaagcg tcgattcaag tgctatcact gttcaaaaat
      241 gatggtcgct gaaacttcta tcgtcaagaa gaatcaccaa atccctcgta tcatcaacca
      301 aaagattgct caaaagttaa ttgaaaagat ttctatgact gatattgccc atcagctttc
      361 catctcaact tcaactgtta ttcgtaagct caatgacttt cactttaaac atgatttttc
      421 ttgtcttcct gagattatgt cttgggatga gtatgctttt acaaaaggaa agatgagctt
      481 cattgcgcaa gattttaaca atctcaatat catcactgtt cttaagggaa gaacacaagc
      541 tgtcatccga aatcactttc ttaaatatga tagagccgtc cgatgtcgcg tcaaaatcat
      601 tactatggat atgtttagtc cttactatga tttagctaga caacttttcc cgtgtgctaa
      661 aatcgtgttg gatcgctttc acattgtaca acatcttagc cgtgctatga gtcgtgtgcg
      721 tgttcaaatc atgaatcagt ttcatcgaaa atcccatgaa tacaaggcta tcaagcgcta
      781 ctggaagctc atacaacagg atagccgtaa actgagtgat aagcgatttt atcgtcctac
      841 ttttcgtatg cacttaacca ataaagagat tttagacaag cttttgagct attcacaaga
      901 cttgaaacac cactatcagc tctatcaact cttgctgttt cactttcaga ataagaaacc
      961 ggagaaattt ttcggactca ttgaggacaa tctaaagc
//
LOCUS       DAVKEV010000113          877 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVKEV010000113 DAVKEV010000000
VERSION     DAVKEV010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..877
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.113"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            97..552
                     /locus_tag="VWZ68_002131"
     CDS             97..552
                     /locus_tag="VWZ68_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9373068.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKMPLLKN"
     gene            549..695
                     /locus_tag="VWZ68_002132"
     CDS             549..695
                     /locus_tag="VWZ68_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9373069.1"
                     /translation="MKEANKNHPAGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVT
                     KYAR"
BASE COUNT          322 a          129 c          161 g          265 t
ORIGIN      
        1 tttttatgtg cagagttata gtggcttgat gctgggaaag tacactgtga ctgctaaaac
       61 attcctagaa gttgctttga tttacctaat ctatttatgc aaattttatg ttattttact
      121 ataacagttg ttgctaagcc aaataatagt ggggaagttc atttagacgt aagcattgaa
      181 gataatcagg gaggtagtgg gcataatttc agttctgttt caagtagctc acaaacagct
      241 aaatatgaag aaactggtta taataacaat tcatcattat atataacgat tgataaaacg
      301 tctgatgcaa cagctctttt gaaattaaag ttgaataatg ttgataatca acctgctact
      361 gaagttccta gttcaggaat tactgtaaaa ttaaatgcta aagataatgc tggaaactgg
      421 acaagtgctt cgaataaaaa agaaataaca gtaaaaattg tttctgctaa accgacatat
      481 ccagacaaaa tcttagtgaa aaatcctgat aatataaaag atacagaaaa aatgccatta
      541 ttgaaaaatt gaaagaggca aataaaaatc atccagcagg agctccaacc tttgctaaag
      601 gtgaaggaga gcatgcaaat gatattgtag caacttattc agatggtaca acttattatg
      661 taccgttaaa tgatgtgaca aaatatgcga ggtagtggct gtaccactca cttattcacc
      721 tccccgtgat ttgtagtagt gataggcttt ctcactatta ttataaaaca aaataaagat
      781 cacaacactt tttcattctg tgttgtgcct tgagtgaaac gaaaggaatg aattataaat
      841 atgaaaagta tagtcactag catagatgag cgcttgc
//
LOCUS       DAVKEV010000114          866 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVKEV010000114 DAVKEV010000000
VERSION     DAVKEV010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..866
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.114"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(1..265)
                     /locus_tag="VWZ68_002133"
                     /pseudo
     CDS             complement(1..265)
                     /locus_tag="VWZ68_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(500..811)
                     /locus_tag="VWZ68_002134"
     CDS             complement(500..811)
                     /locus_tag="VWZ68_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9373070.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCSFCFSRFNPGCQNHKERYF
                     K"
BASE COUNT          275 a          171 c          138 g          282 t
ORIGIN      
        1 catccacagc cgccttgtag cagttggtta ctgttgatac gtagtgaata gacttcatac
       61 gtccttcgat ttttagactg tccacaccat tttcaatcat atctggaatg tggtcaatca
      121 tagacatgtc aacggctgac attgaaaatt cttctggaat ctcaccctgc aaactcttac
      181 gttctttccc aaatggcata tcgtaaaggt cgtatttcca acggcatgac tgagaacatc
      241 caccacggtt ggcatcacgc atactctaga cgcaattcta atcttttaga ctttgcataa
      301 taactgttaa acagttgaaa attaacccag ttttaacaag tagtcaaaat accagataaa
      361 ggaaaaaagt ctttaaaatc ttaaaaacgc atagtatcag gtattgaaca atcttgatat
      421 tatgcgtttt attgtgggaa gatttacttc attttctctt ggaattgagt tttctcctac
      481 ttcaaaacta gatgatttgc tatttaaaat agcgttcctt atgattttgg caacctggat
      541 taaagcgaga aaaacaaaag gagcaactta aactttcttt atattgctta tatgttagta
      601 gttttagaca aacaccacat aaaataggct tatcctgtat caaagataag ggatacggct
      661 caaaagggtg attttctaat gaatcatgac accgataaca agcatagtac tttttacaat
      721 catagcattg taaagcaata atatccaact tgctatggta atgaatgcat cttgtttgct
      781 tatccactaa gaaaccctgt gcctctatca tttccttttc ctttcttaag cacgaactgt
      841 gacgctggtt ccatcttcct tataaa
//
LOCUS       DAVKEV010000115          838 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVKEV010000115 DAVKEV010000000
VERSION     DAVKEV010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.115"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..792
                     /locus_tag="VWZ68_002135"
     CDS             <1..792
                     /locus_tag="VWZ68_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY-like element IS1202 family transposase"
                     /protein_id="HEU9373071.1"
                     /translation="FDKQETLNAYYHVLEQILANHGIPLQMKTDKRTVFTYQASNSKK
                     MEDDTYTQFGYACHQLGILLETTSIPQAKGRVERLNQTLQSRLPIELERNKIHTLEEA
                     NTFLLSYIQTFNEQFGNKTKLSVFEEAPNPSERNLILARLAERVVDSGHHIRFQNRCY
                     IPTEQGKEVYFIRKTKALVLKAFDGDIYLNIADKIYHTKELLDHELYSKNFEQEPEQK
                     KERRKYIPPQTHPWKLTSFKQYLHKNKKDYEEFTSEEIHSPQLQV"
BASE COUNT          299 a          200 c          136 g          203 t
ORIGIN      
        1 tttgacaaac aagagacctt gaatgcctac taccatgtcc tcgaacaaat cttagccaat
       61 cacggcattc cccttcaaat gaaaactgat aagagaacgg tctttaccta tcaagcatcc
      121 aactctaaga aaatggagga cgacacctat acacaatttg gatacgcctg tcaccaacta
      181 gggattctcc ttgagaccac ctctatccct caagctaaag ggagggtcga aagactcaat
      241 cagacactac aatcacgcct gcctatcgaa ctggaacgaa acaagattca tacattggaa
      301 gaagccaata ctttccttct ttcctacatc caaaccttta atgaacagtt tggaaataag
      361 acaaaactct ctgtttttga ggaggctcct aacccctctg aacggaatct cattctagct
      421 agactggcgg agagagtcgt cgatagtgga caccatatcc gattccaaaa ccgttgctat
      481 attcctaccg aacaaggaaa agaagtctat ttcatcagaa agacgaaagc attagttcta
      541 aaagcatttg atggtgacat ctacctcaat atcgctgaca aaatctatca cacaaaggag
      601 ctactagatc atgaactcta ttcgaaaaac tttgaacaag aaccagaaca aaaaaaagaa
      661 agacgcaagt atatccctcc acaaacccat ccgtggaaac tcacatcttt caaacaatac
      721 cttcataaaa acaaaaagga ttatgaagag tttactagtg aggagattca ttctcctcaa
      781 ctacaagtat aatctatttt tcgctaaatg ggaagctttt ccttaaagga agtcactc
//
LOCUS       DAVKEV010000116          806 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVKEV010000116 DAVKEV010000000
VERSION     DAVKEV010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..806
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.116"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>806
                     /gene="phtD"
                     /locus_tag="VWZ68_002136"
     CDS             <1..>806
                     /gene="phtD"
                     /locus_tag="VWZ68_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEU9373072.1"
                     /translation="YTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHS
                     HWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPL
                     DRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYV
                     EHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPNEEKPQTEKPEEDKEHDEVSEP
                     THPESDEKENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSV"
BASE COUNT          285 a          160 c          180 g          181 t
ORIGIN      
        1 tacactgatg atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt
       61 tatatctttg atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat
      121 atgacccata gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc
      181 caggcttatg ctaaagagaa aggtttgacc cctccttcga cagaccatca ggattcagga
      241 aatactgagg caaaaggagc agaagctatc tacaaccgcg tgaaagcagc taagaaggtg
      301 ccacttgatc gtatgcctta caatcttcaa tatactgtag aagtcaaaaa cggtagttta
      361 atcatacctc attatgacca ttaccataac atcaaatttg agtggtttga cgaaggcctt
      421 tatgaggcac ctaaggggta tactcttgag gatcttttgg cgactgtcaa gtactatgtc
      481 gaacatccaa acgaacgtcc gcattcagat aatggttttg gtaacgctag cgaccatgtt
      541 caaagaaaca aaaatggtca agctgatacc aatcaaacgg aaaaaccaaa cgaggagaaa
      601 cctcagacag aaaaacctga ggaagataag gaacatgatg aagtaagtga gccaactcac
      661 cctgaatctg atgaaaaaga gaatcacgct ggtttaaatc cttcagcaga taatctttat
      721 aaaccaagca ctgatacgga agagacagag gaagaagctg aagatactac agatgaggct
      781 gaaattcctc aagtagagca ttctgt
//
LOCUS       DAVKEV010000117          797 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVKEV010000117 DAVKEV010000000
VERSION     DAVKEV010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..797
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.117"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..796
                     /locus_tag="VWZ68_002137"
     rRNA            <1..796
                     /locus_tag="VWZ68_002137"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          204 a          174 c          243 g          176 t
ORIGIN      
        1 cacatgtaca ggataggtag gagtctaaga gatcgggacg ccagtttcga aggagacgct
       61 gttgggatac tacccttgtg ttatggccac tctaacccag ataggtgatc cctatcggag
      121 acagtgtctg acgggcagtt tgactggggc ggtcgcctcc taaaaggtaa cggaggcgcc
      181 caaaggttcc ctcagaatgg ttggaaatca ttcgcagagt gtaaaggtat aagggagctt
      241 gactgcgaga gctacaactc gagcagggac gaaagtcggg cttagtgatc cggtggttcc
      301 gtatggaagg gccatcgctc aacggataaa agctaccctg gggataacag gcttatctcc
      361 cccaagagtt cacatcgacg gggaggtttg gcacctcgat gtcggctcgt cgcatcctgg
      421 ggctgtagtc ggtcccaagg gttgggctgt tcgcccatta aagcggcacg cgagctgggt
      481 tcagaacgtc gtgagacagt tcggtcccta tccgtcgcgg gcgtaggaaa tttgagagga
      541 tctgctccta gtacgagagg accagagtgg acttaccgct ggtgtaccag ttgtcttgcc
      601 aaaggcatcg ctgggtagct atgtagggaa gggataaacg ctgaaagcat ctaagtgtga
      661 aacccacctc aagatgagat ttcccatgat tatatatcag taagagccct gagagatgat
      721 caggtagata ggttagaagt ggaagtgtgg cgacacatgt agcggactaa tactaatagc
      781 tcgaggactt atccaaa
//
LOCUS       DAVKEV010000118          791 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVKEV010000118 DAVKEV010000000
VERSION     DAVKEV010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.118"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(50..>791)
                     /locus_tag="VWZ68_002138"
     CDS             complement(50..>791)
                     /locus_tag="VWZ68_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HEU9373073.1"
                     /translation="LEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDNWTSNLQ
                     NPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFMENRLKE
                     FFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVITLDTSIY
                     TNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSIVFFPVG
                     AYIKSNHSNLHRNDFMREVYLWTKNLTY"
BASE COUNT          263 a          136 c           98 g          294 t
ORIGIN      
        1 ttatccagaa tttgagtagt tttatttcct aaatattcct taactttatc taatatgtca
       61 agttttttgt ccacaaatat acctcccgca taaaatcatt acgatgtaaa tttgaatgat
      121 tgctttttat ataagctcct acaggaaaaa acactatact gctattttga gttaaccttg
      181 gaagcgaaac tttcatttta tacttgtcat gttcataaca ggtattacca tagagaatag
      241 tactataacg ctctttacta cttgaattta acgttgtaat aatatgcgga acaaaccata
      301 atgtattggt gtatattgat gtgtctaacg tgataacctg ctgctcattc acctcactaa
      361 cattaactgg gctagtaatc atataggcag aaaatgaagt aattgcacta cctggttcta
      421 ttattgtagt cacagtacta tcaatatcgt actttttata gatttccata agtgatagaa
      481 aaaattcttt caaacgattt tccataaata atttcataaa accgcctcca agatttattt
      541 ctctaacctc tctaagttta ttaatttctt gtaacttaaa taatatttta tctaacttaa
      601 caataaattt atcatctttt tctccaaaat gaaaatgcag tcgtgtaatt aaaggatttt
      661 gtaaattact agtccaatta tcactgcaaa tatttattcc aaatcgactc atacgattat
      721 taagttcatc tggctccgtt actcttattc caacagattc ttttggggaa aattgttgaa
      781 gatgttccaa a
//
LOCUS       DAVKEV010000119          737 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVKEV010000119 DAVKEV010000000
VERSION     DAVKEV010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..737
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.119"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            224..442
                     /locus_tag="VWZ68_002139"
     CDS             224..442
                     /locus_tag="VWZ68_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9373074.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
BASE COUNT          326 a           85 c          124 g          202 t
ORIGIN      
        1 cagacgatag aaattaaaaa ctctatcgtc ttttttatac tcaaaattag gaggtaaaaa
       61 tggtaaggat aagaggtccc acttaaaaca atttatggca aaataaggac ggaataacac
      121 aacaaattct ctaaaacaaa tcactaaatc aatgtaagat tgaatgaaat caatatttat
      181 gctataatta aataaatcta atgaagaaaa aaagagggat attatggcac ttaactataa
      241 accattatgg atacagttag caaaaaaagg actaaagaaa acagatgtaa tagctatggc
      301 aggacttaca acaaatgtta tggcacaaat gggaaaggat aaaccaatta catttaagaa
      361 tttagaaaga atatgtaagg ctttatcttg cactcctaat gatattatta gttttgaaga
      421 taattttagt gacgaggaat agaaaatgac tttaaggaca gaagatcaag ttagggatta
      481 tgcaagagaa gtataggctt taatgaagtt gaagaaaaca tcaatcaagg tactggtcaa
      541 ataactactt ttaatcaatt aggcttcaag ggatattcag ataagccaga tggttggtat
      601 ttacctaaaa atatgaatga tgtagcaata atccttgaaa caaaatcaga agaaagagat
      661 attagcaaac aaatttttat tgatgagtta atgaaaaata tagacataat ttaactaaaa
      721 ataaaaacta gatcctt
//
LOCUS       DAVKEV010000120          701 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVKEV010000120 DAVKEV010000000
VERSION     DAVKEV010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..701
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.120"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            315..614
                     /locus_tag="VWZ68_002140"
     CDS             315..614
                     /locus_tag="VWZ68_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEU9373075.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT          265 a          131 c          117 g          188 t
ORIGIN      
        1 aatagacaac tatttatcca aaaatagata gatgtaacat gtttgcaaac aaagcatacg
       61 aacctttagt aaaatcattt ccatgaaact agaatagagc cctcttagca aaaatcatta
      121 ttttaattta tttctaatca ctccttgaca taaataactc tcaccaataa aagactatgt
      181 cttaaaaaaa tggtataata aaatcaatac ttgggcttga tggctatgct actaataaca
      241 attaggagag aaaatcaggc acttgttaac aacaaggatt atccccttga gatgaaagga
      301 actttagaaa tcttatgatg aacatgcaaa acatgatgcg tcaagcacaa aaacttcaaa
      361 aacaaatgga acaaagccaa gctgaacttg ctgctatgca atttgttggc aaatctgctc
      421 aagatcttgt ccaagcgacc ttaactggcg ataagaaagt tgtcagcatt gatttcaatc
      481 cagctgtcgt tgacccagag gaccttgaga ctctttctga tatgaccgtt caagccatca
      541 actctgctct tgaacaaatc gatgaaacta ccaagaaaaa actgggtgct ttcgctggga
      601 aattaccttt ctaaaaacaa ggagctagaa caatgcttgt cgataacaaa ggctaagaaa
      661 ggtgcaaaaa tgactctata atatttgtag tgggtaaatc c
//
LOCUS       DAVKEV010000121          701 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVKEV010000121 DAVKEV010000000
VERSION     DAVKEV010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..701
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.121"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            231..>701
                     /locus_tag="VWZ68_002141"
     CDS             231..>701
                     /locus_tag="VWZ68_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEU9373076.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKP"
BASE COUNT          254 a          116 c          150 g          181 t
ORIGIN      
        1 taccttagtc aagaattaga tgtttcacta tgtttgagta agttgatgat ttcatttgat
       61 aacaggtttg aaactgttag gctaggtggc caaggctaat catagccttg gtttagctga
      121 aaaaacaggt tcaagggttc ctgttgtcaa atgaaatgtg atttaaggta taagaaaaca
      181 cctctgtgct atacttgttg ttcaccacaa acacaaggaa aggcacagag atgcaagaac
      241 attatacccc aaaagggaaa catttgacaa tagataaccg tcgcttgatt gagcggtgga
      301 agaatgaaaa taagtccaat cgtgaaattg caggcttgtt aggaaaggcg cctcaaacga
      361 ttcataatga agtcaaaaga ggtacaactt tacaacaagt gagaaaaggg ctatacaaaa
      421 aggtctattc tgccgattac gcacaaactg tttaccaatt caatcgaaaa cggtcggtga
      481 aaaagttaat tttaacaaag gaaatcagag agaagatctt acactatcat aagcaaaaat
      541 tttcgcctga aatgatggtt aacaagaagc aagtgaaagt tggtatttca accatctact
      601 actggtttca taatggtcat ttaggattga cgaaggccga catgctttat cccagaaaaa
      661 ggaaaggtgt caagaagcaa gctagtccga actttaagcc g
//
LOCUS       DAVKEV010000122          642 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVKEV010000122 DAVKEV010000000
VERSION     DAVKEV010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..642
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.122"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            105..584
                     /locus_tag="VWZ68_002142"
     CDS             105..584
                     /locus_tag="VWZ68_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU9373077.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGELSHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          242 a           82 c          149 g          169 t
ORIGIN      
        1 gcctctcttt tttgtgcagt ttaggagcta aagggaacag aatggagaaa atggaacaaa
       61 tgtgttttct aatctgttag actgtatcta gaaaggggaa aattatgatt aaagaattgt
      121 atgaagaagt ccaagggact gtgtataagt gtagaaatga atattacctt catttatggg
      181 aattatcgga ttgggaccaa gaaggcatgc tctgcttaca tgaattgatt agtagagaag
      241 aaggactggt agacgatatt ccacgtttaa ggaaatattt caaaaccaag tttcgaaatc
      301 gaattttaga ctatatccgt aagcaggaaa gtcagaagcg tagatacgat aaagaaccct
      361 atgaagaagt gggtgagctc agtcatcgta taagtgaggg gggtctctgg ctagatgatt
      421 attatctctt tcatgaaaca ctaagagatt atagaaacaa acaaagtaaa gagaaacaag
      481 aagaactaga acgtgtctta agcaatgaac gatttcgagg gcgtcaaaga gtattaagag
      541 acttacgcat tgtgtttaag gagtttacta tccgtaccca ctaggaagtc atgcaaaaaa
      601 aatgaaaaaa attagaaaaa gtagttgaca aagtttgaaa ag
//
LOCUS       DAVKEV010000123          636 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVKEV010000123 DAVKEV010000000
VERSION     DAVKEV010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..636
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.123"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..513
                     /locus_tag="VWZ68_002143"
                     /pseudo
     CDS             1..513
                     /locus_tag="VWZ68_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          239 a          108 c          115 g          174 t
ORIGIN      
        1 taaaccacca agtaaaagga acaaaaccaa gaaaagttga tagagataga cttaaaaact
       61 atcttactga caatccagac gcttatttga ctgaaatagc ttctgaattt ggctgtcatc
      121 caactaccat ccactatgcg ttcaaagcta tgggctacac tcgaaaaaaa gaaccacacc
      181 tactatgaac aagacccaga aaaagtagcc ttatttctta agaattttaa tagattaaag
      241 cacctagcac ctgtttagat tgacgaaaca ggattcgata cttattttta tcgagaatat
      301 ggtcgctcat taaaaggtca gttaagaaga ggcaaagtat ctggaagaag atatcagagg
      361 atttctttgg ttgcaggtct aacaaatggt gagttaatcg ctccaataac ttacgaagag
      421 acgatgacga gcgacttttt tgaagtatgg tttcagaaat ttctcttacc aacattaaac
      481 acaccatcgg ttattatagt aaaacgaaat aagaatagga caaatcgatc aggacagtaa
      541 aatcgaattc taacaatgtt ttagaagtag atgtgtacta ttctagtttc aatctactat
      601 attatggata atgcaagatt ccatagaatg gggaag
//
LOCUS       DAVKEV010000124          620 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVKEV010000124 DAVKEV010000000
VERSION     DAVKEV010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..620
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.124"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..612)
                     /locus_tag="VWZ68_002144"
     CDS             complement(<1..612)
                     /locus_tag="VWZ68_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase"
                     /protein_id="HEU9373078.1"
                     /translation="MFHLSEWKRNEEFDFFNKMDVPYLSMSSRIEVTQAINFHKKHSI
                     SLYAIISWCVMSAINSIPELLMDTDGKIVWQYNQRGCSFTTLTSEDKLNFSSFTMGDN
                     LIEFVSAFNINKQKAEEGQKPNIDKNNIAYLSCVPWIDFLHVSTPMNLSKIDTVPRIT
                     WGKVIQENQRYFCTVNLQINHGMGDGLHVSNFFVLLQRFVNKIN"
BASE COUNT          209 a          111 c           83 g          217 t
ORIGIN      
        1 atttatttta tttacaaacc tttgcaataa cacaaaaaaa ttagatacgt gtaatccatc
       61 tcccattcca tgattaattt gtaaattcac tgtacaaaaa tatctttggt tctcttgaat
      121 aacttttccc cacgttattc gaggaactgt atcaattttt gaaagattca taggagtgct
      181 tacatgtaaa aaatcaatcc atggaacaca agaaagataa gcaatgttat tcttgtcaat
      241 atttggtttt tgcccttctt ctgccttctg tttatttatg ttgaacgcag aaacaaattc
      301 aattaaatta tctcccatcg taaatgaaga aaaattaagc ttatcttccg atgtaagggt
      361 agtgaaagaa caacctcttt gattgtattg ccagacaatc tttccgtcgg tatccattag
      421 taattctgga atagaattta ttgcactcat aacacaccac gatattatgg cataaagtga
      481 tatcgaatgt tttttatgaa aattgatagc ctgcgttact tctattcgtg aactcataga
      541 taaataagga acatccattt tattgaaaaa gtcaaattct tcattccttt tccactctga
      601 taaatgaaaa attccatccc
//
LOCUS       DAVKEV010000125          613 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVKEV010000125 DAVKEV010000000
VERSION     DAVKEV010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..613
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.125"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(29..601)
                     /locus_tag="VWZ68_002145"
     CDS             complement(29..601)
                     /locus_tag="VWZ68_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9373079.1"
                     /translation="MFLIKFLMRIFPTENYVINTGFWNLLSNPSYLKSIQTSMSMGVT
                     LISGFILYTQNMYSFMNTANGVNEARASFIAYMSAPIILIITSSISLTILSSNKDIED
                     IKQLKTLGVSRLQLFKIRIGEAIIHSVLILLVSVIFNLIILILVSIIGQFLGRSLVDI
                     SGFWQPSLIVISLLVIFYSITKGFYLFQDR"
BASE COUNT          234 a           91 c           83 g          205 t
ORIGIN      
        1 ttctttttgg ttcagtaact attccaattt atctatcttg aaataaataa aatccctttg
       61 taatactata aaaaataact aacaaagaaa taactataag actcggttgc cagaaacctg
      121 atatatctac taaactacga cctaaaaatt ggccaataat gctaactaaa attaaaataa
      181 ttaaattgaa aattactgac actaataaaa ttaacaccga atgtattatt gcctcgccta
      241 tacgtatttt aaaaagttgt aatcttgaca ctcccagtgt ctttaactgt ttaatgtcct
      301 caatatcttt attagaagat aaaattgtaa gagaaataga actagtaata atcagaataa
      361 ttggtgcaga catataagca ataaaggaag ctcttgcttc gtttactccg tttgctgtat
      421 tcatgaatga atacatattt tgggtgtaaa gaataaaccc agaaatgaga gttactccca
      481 tgctcattga agtttgtata cttttcaaat agctaggatt ggatagtaga ttccaaaagc
      541 ctgtattaat tacataattt tcagttggaa atatcctcat taaaaatttt attagaaaca
      601 tttgaattga tgg
//
LOCUS       DAVKEV010000126          544 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVKEV010000126 DAVKEV010000000
VERSION     DAVKEV010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..544
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.126"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>544
                     /locus_tag="VWZ68_002146"
     CDS             <1..>544
                     /locus_tag="VWZ68_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9373080.1"
                     /translation="SEKVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNH
                     SYRFLCSPIITDDFLNTKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMS
                     AIKLCLEILNSIFFKKKIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYN
                     VFMMEPNRADLTLQKTDFKIV"
BASE COUNT          203 a           62 c           88 g          191 t
ORIGIN      
        1 tcagaaaaag tattaaacaa ttcttttaat tttacgagta aagaatttaa tgatttaatt
       61 aataacgaaa attatttatt cgaatatgca tgtagaatta gagaggaatg gagaaaaaaa
      121 tgctttaatc attcttatcg ttttctatgc tcacctataa ttacagatga ttttcttaac
      181 acgaagacat tgagaagtag ccaaattgaa tataaatatg agcgatattt atcgaaaagt
      241 tcgataggcg atagagcggt tgatggcttt gtttccttca atactttaac agctaatggt
      301 atgtctgcta ttaaactatg tcttgagata ttaaactcta ttttcttcaa gaagaagatt
      361 gatttattat attcaaccgg atattatgaa acaagatttt tattaaataa tcttgctaaa
      421 tcaggtatta gttgctatga ggtaagtaat tgtgaattgg ataaagataa attttataat
      481 gtattcatga tggaacccaa tcgagccgat ttaacattac aaaaaactga tttcaagata
      541 gtag
//
LOCUS       DAVKEV010000127          452 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVKEV010000127 DAVKEV010000000
VERSION     DAVKEV010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.127"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..452
                     /locus_tag="VWZ68_002147"
                     /pseudo
     CDS             1..452
                     /locus_tag="VWZ68_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          166 a           90 c           73 g          123 t
ORIGIN      
        1 tcttcttcta aaagccatta aactagctcg ttcgacctac tactatcact tgaaacagct
       61 agacaaaaca gataaggacc aagagcttaa agctgaaatt caatccatct ttatcgaaca
      121 caagggaaat tatgcttatc gtcggattta tttagaacta agaaatcgtg gttatctggt
      181 aaatcataaa agagttcaac acttgatgaa gtactcaatt tacaagctaa aacgcgacag
      241 aaacgaaaat attcttctca taaaggagac gttggcaaga aagcagagaa tctcattcaa
      301 ggccaatttg aaggctctaa aacaatggaa cagtgctaca cagatgtgac tgaatttgcc
      361 attccagtaa gtactcaaaa gctttactta tcaccagttt tagatggctt taatagcgaa
      421 attatcgcct ataatctttc aacttcaccc aa
//
LOCUS       DAVKEV010000128          442 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVKEV010000128 DAVKEV010000000
VERSION     DAVKEV010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.128"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(1..442)
                     /locus_tag="VWZ68_002148"
                     /pseudo
     CDS             complement(1..442)
                     /locus_tag="VWZ68_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          123 a           75 c           83 g          161 t
ORIGIN      
        1 ttaggcgaac aagaaagatt ataggcgata atttcgctgt taaagccatc taaaactggt
       61 gataagtaaa gcttttgagt acttgctgga atggcaaatt ctgtcacatc tgtgtagcac
      121 tgttccattg ttttagagcc ttcaaattgg ccttgaatga gattctctgc cttcttacca
      181 acgtctcctt tattttcgtt tctgtcgcat tttagcttgt aaattgagta ctttcatcaa
      241 gccttgaact cttttatgat ttaccaaata agcacgattt cttagttcta aatgaataca
      301 gcgataagca taatttccct tgtgttcgat aaaaatggat tgaatttcag ctttaagctc
      361 ttggtcctta tctgttttgt ctagctgttt caagtgatag tagtaggtcg aacaagctag
      421 tttaatggat tttagaagaa ga
//
LOCUS       DAVKEV010000129          379 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVKEV010000129 DAVKEV010000000
VERSION     DAVKEV010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..379
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.129"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..345)
                     /locus_tag="VWZ68_002149"
     CDS             complement(<1..345)
                     /locus_tag="VWZ68_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HEU9373081.1"
                     /translation="MWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVVSYD
                     DAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELLTIK
                     VPQPVQSGDMVRA"
BASE COUNT          101 a           88 c           77 g          113 t
ORIGIN      
        1 tgcacgaacc atgtctcctg attgaacggg ttgtgggact ttaatagtca atagttccat
       61 tggatttgga gcgcggtcga ttttattgcc tttggcatca tgcaaatctt caatataggt
      121 ttcaaaatga cggaaacctg gaccataaaa ctcaacttgg tccccttcgt taatgacgtt
      181 tcgttgacga atggttgctg tttgtgccgc atcatcataa gaaaccactt cagcgacaaa
      241 cttgtactca ggaattttac ggcgagcacc aaacaactgc tcattttcag atggtatacc
      301 gtagtagaaa cctgttgcca attcacgttg ggcaaccttc cacatctcgt ccaccaagtc
      361 ttgtttgata gcttcaaac
//
LOCUS       DAVKEV010000130          334 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVKEV010000130 DAVKEV010000000
VERSION     DAVKEV010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.130"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>334
                     /locus_tag="VWZ68_002150"
     CDS             <1..>334
                     /locus_tag="VWZ68_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEU9373082.1"
                     /translation="ETYKPNVLHFCELLAEEEGIKLSDTTVRKILYKKNILSPKSHRK
                     TKKRVRKQAKLNLNQPLDNPILPTAKDFLEDPKKVHPSRPRKKFAGELIQMDASPHAW
                     FGPETTNL"
BASE COUNT          130 a           76 c           55 g           73 t
ORIGIN      
        1 atgaaacata taaaccaaat gtccttcatt tctgtgaatt actagctgaa gaagagggaa
       61 ttaagctctc tgatacaact gttagaaaaa tactctataa gaaaaacatc ctttctccta
      121 agtctcacag aaagacaaag aagagagtaa gaaaacaagc taaactgaac ctgaatcaac
      181 ccctagacaa tccaatctta ccgacggcta aagacttcct ggaagaccct aaaaaggtac
      241 atcctagtag acccagaaag aaatttgctg gagaactcat tcaaatggat gccagccctc
      301 atgcctggtt tggaccagaa accaccaact taca
//
LOCUS       DAVKEV010000131          306 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00074582
            SAMN33606193-rid17945753.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVKEV010000131 DAVKEV010000000
VERSION     DAVKEV010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606193
            Sequence Read Archive: SRR23727536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722578.1
            Genome Coverage       :: 137x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:11:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,969
            CDSs (with protein)               :: 1,969
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 72 of 134
            Pseudo Genes (incomplete)         :: 60 of 134
            Pseudo Genes (internal stop)      :: 36 of 134
            Pseudo Genes (multiple problems)  :: 28 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606193-rid17945753.denovo.131"
                     /strain="AUSMDU00074582"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            145..>306
                     /locus_tag="VWZ68_002151"
     rRNA            145..>306
                     /locus_tag="VWZ68_002151"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          102 a           55 c           85 g           64 t
ORIGIN      
        1 tcgcttgaga gaagcaagtg acaaagacct ttgaaaactg aacaagacga accaatgtgc
       61 agggcgctac aacataagtt gtagtactga acaatgaaaa aacaataaat ctgtcagtga
      121 cagaaatgag tgagaactca aacttttaat gagagtttga tcctggctca ggacgaacgc
      181 tggcggcgtg cctaatacat gcaagtagaa cgctgaagga ggagcttgct tctctggatg
      241 agttgcgaac gggtgagtaa cgcgtaggta acctgcctgg tagcggggga taactattgg
      301 aaacga
//
